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-%dl
- %dt
- [
- %a{ :name => "maunz08b" }
- 1
- ]
- %dd
- A. Maunz and C. Helma.
- Prediction of toxic effects of pharmaceutical agents.
- In K. V. Balakin, editor,
- %em
- Pharmaceutical Data Mining: Approaches
- and Applications for Drug Discovery
- , New York, 2009. J. Wiley & Sons, Inc.
- [ 
- %a{ :href => "http://www.in-silico.de/articles/chapter_mh.pdf" }
- \.pdf
- \ ]
- %dt
- [
- %a{ :name => "maunz09a" }
- 2
- ]
- %dd
- A. Maunz, C. Helma, and S. Kramer.
- Large-scale graph mining using backbone refinement classes.
- In
- %em
- Proceedings of the 15th ACM SIGKDD International Conference
- on Knowledge Discovery and Data Mining (KDD-09)
- , page in press, 2009.
- [ 
- %a{ :href => "http://www.maunz.de/ls_graph_mining_using_bbrcs.pdf" }
- \.pdf
- \ ]
- %dt
- [
- %a{ :name => "hammann09a" }
- 3
- ]
- %dd
- F. Hammann, H. Gutmann, U. Jecklin, A. Maunz, C. Helma, and J. Drewe.
- Development of decision tree models for substrates, inhibitors and
- inducers of P-glycoprotein.
- %em
- Current Drug Metabolism
- , 10:339-46, 2009.
- %dt
- [
- %a{ :name => "hammann09b" }
- 4
- ]
- %dd
- Felix Hammann, Heike Gutmann, Ulli Baumann, Christoph Helma, and Juergen Drewe.
- Classification of cytochrome p(450) activities using machine learning
- methods.
- %em
- Molecular pharmaceutics
- , 6:1920-6, 2009.
- %dt
- [
- %a{ :name => "maunz08a" }
- 5
- ]
- %dd
- A. Maunz and C. Helma.
- Prediction of chemical toxicity with local support vector regression
- and activity-specific kernels.
- %em
- SAR QSAR Environ. Res.
- , 19:413-431, 2008.
- [ 
- %a{ :href => "http://www.in-silico.de/articles/mh_tf.pdf" }
- \.pdf
- \ ]
- %dt
- [
- %a{ :name => "benigni07" }
- 6
- ]
- %dd
- R. Benigni, T. I. Netzeva, E. Benfenati, C. Bossa, R. Franke, C. Helma,
- E. Hulzebos, C. Marchant, A. Richard, Y.-T. Woo, and C. Yang.
- The expanding role of predictive toxicology: an update on the (Q)SAR
- models for mutagens and carcinogens.
- %em
- J Environ Sci Health C Environ Carcinog Ecotoxicol Rev.
- ,
- 25:53-97, 2007.
- %dt
- [
- %a{ :name => "helma06a" }
- 7
- ]
- %dd
- C. Helma.
- Lazy structure-activity relationships (
- %tt
- lazar
- ) for the
- prediction of rodent carcinogenicity and
- %em
- Salmonella
- mutagenicity.
- %em
- Molecular Diversity
- , 10:147-158, 2006.
- [ 
- %a{ :href => "http://www.in-silico.de/articles/modi020905.pdf" }
- \.pdf
- \ ]
- %dt
- [
- %a{ :name => "helma06b" }
- 8
- ]
- %dd
- C. Helma and J. Kazius.
- Artificial intelligence and data mining for toxicity prediction.
- %em
- Current Computer-Aided Drug Design
- , 2:1-19, 2006.
- [ 
- %a{ :href => "http://www.in-silico.de/articles/helma_kazius_ccadd.pdf" }
- \.pdf
- \ ]
- %dt
- [
- %a{ :name => "vracko06" }
- 9
- ]
- %dd
- M. Vracko, V. Bandelj, P. Barbieri, E. Benfenati, Q. Chaudhry, M. Cronin,
- J. Devillers, A. Gallegos, G. Gini, P. Gramatica, C. Helma, D. Neagu,
- T. Netzeva, M. Pavan, G. Patlevicz, M. Randic, I. Tsakovska, and A. Worth.
- Validation of counter propagation neural network models for
- predictive toxicology according to the OECD principles. A case study.
- %em
- SAR QSAR Environ. Res.
- , 17:265-84, 2006.
- %dt
- [
- %a{ :name => "helma05a" }
- 10
- ]
- %dd
- C. Helma.
- %em
- Predictive Toxicology
- \.
- CRC Press, Boca Raton, 2005.
- %dt
- [
- %a{ :name => "helma05b" }
- 11
- ]
- %dd
- C. Helma.
- %tt
- lazar:
- Lazy Structure - Activity Relationships for toxicity
- prediction.
- In C. Helma, editor,
- %em
- Predictive Toxicology
- , pages 479-499. CRC
- Press, Boca Raton, 2005.
- %dt
- [
- %a{ :name => "helma05c" }
- 12
- ]
- %dd
- C. Helma.
- %em
- In Silico
- predictive toxicology: The state-of-the-art and
- strategies to predict human health effects.
- %em
- Current Opinions in Drug Discovery & Development
- , 8:27-31,
- 2005.
- [ 
- %a{ :href => "http://www.in-silico.de/articles/helma_coddd.pdf" }
- \.pdf
- \ ]
- %dt
- [
- %a{ :name => "helma05d" }
- 13
- ]
- %dd
- C. Helma.
- A brief introduction to predictive toxicology.
- In C. Helma, editor,
- %em
- Predictive Toxicology
- \. CRC Press, Boca
- Raton, 2005.
- %dt
- [
- %a{ :name => "kramer05" }
- 14
- ]
- %dd
- S. Kramer and C. Helma.
- Machine learning and data mining.
- In C. Helma, editor,
- %em
- Predictive Toxicology
- , pages 223-254. CRC
- Press, Boca Raton, 2005.
- %dt
- [
- %a{ :name => "helma04a" }
- 15
- ]
- %dd
- C. Helma, T. Kramer, S. Kramer, and L. DeRaedt.
- Data Mining and Machine Learning techniques for the
- identification of mutagenicity inducing substructures and
- Structure-Activity Relationships of noncongeneric compounds.
- %em
- J. Chem. Inf. Comput. Sci.
- , 44:1402-1411, 2004.
- [ 
- %a{ :href => "http://pubs3.acs.org/acs/journals/doilookup?in_doi=10.1021/ci034254q" }
- http
- \ ]
- %dt
- [
- %a{ :name => "helma04b" }
- 16
- ]
- %dd
- C. Helma.
- Data mining and knowledge discovery in predictive toxicology.
- %em
- SAR QSAR Environ. Res.
- , 15:367-383, 2004.
- %dt
- [
- %a{ :name => "helma03a" }
- 17
- ]
- %dd
- C. Helma and S. Kramer.
- A survey of the Predictive Toxicology Challenge.
- %em
- Bioinformatics
- , 19:1179-1182, 2003.
- [ 
- %a{ :href => "http://bioinformatics.oxfordjournals.org/cgi/content/abstract/19/10/1179" }
- http
- \ ]
- %dt
- [
- %a{ :name => "helma03b" }
- 18
- ]
- %dd
- C. Helma, S. Kramer, and L. DeRaedt.
- The molecular feature miner MolFea.
- In M. Hicks and C. Kettner, editors,
- %em
- Proceedings of the
- Beilstein Workshop 2002: Molecular Informatics: Confronting Complexity
- ,
- pages 79-93. Beilstein Institut, Frankfurt, 2003.
- %dt
- [
- %a{ :name => "toivonen03" }
- 19
- ]
- %dd
- H. Toivonen, A. Srinivasan, R. D. King, S. Kramer, and C. Helma.
- Statistical evaluation of the Predictive Toxicology Challenge
- 2000-2001.
- %em
- Bioinformatics
- , 19:1183-1193, 2003.
- [ 
- %a{ :href => "http://bioinformatics.oxfordjournals.org/cgi/content/abstract/19/10/1183" }
- http
- \ ]
- %dt
- [
- %a{ :name => "helma02a" }
- 20
- ]
- %dd
- C. Helma.
- Data mining in toxicology.
- In J.P.V. Heuvel, W.F. Greenlee, G.H. Perdew, and W.B. Mattes,
- editors,
- %em
- Comprehensive Toxicology Vol XX. Cellular and Molecular
- Toxicology
- , pages 611-624. Elsevier, 2002.
- %dt
- [
- %a{ :name => "kassie02" }
- 21
- ]
- %dd
- F. Kassie, S. Rabot, M. Uhl, W. Huber, H.M. Qin, C. Helma, R. Schulte-Hermann,
- and S. Knasmüller.
- Chemoprotective effects of garden cress (lepidium sativum) and its
- constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced
- genotoxic effects and colonicneoplastic lesions.
- %em
- Carcinogenesis
- , 23:1155-1161, 2002.
- %dt
- [
- %a{ :name => "kramer02" }
- 22
- ]
- %dd
- S. Kramer, E. Frank, and C. Helma.
- Fragment generation and Support Vector Machines for inducing
- SARs.
- %em
- SAR and QSAR in Environmental Research
- , 13:509-523, 2002.
- %dt
- [
- %a{ :name => "gottmann01" }
- 23
- ]
- %dd
- E. Gottmann, S. Kramer, B. Pfahringer, and C. Helma.
- Data quality in predictive toxicology: Reproducibility of rodent
- carcinogenicity experiments.
- %em
- Environ. Health Perspect.
- , 109:509-514, 2001.
- [ 
- %a{ :href => "http://www.ehponline.org/members/2001/109p509-514gottmann/gottmann-full.html" }
- \.html
- \ ]
- %dt
- [
- %a{ :name => "helma01b" }
- 24
- ]
- %dd
- C. Helma, R.D. King, S. Kramer, and A. Srinivasan.
- The Predictive Toxicology Challenge 2000-2001.
- %em
- Bioinformatics
- , 17:107-108, 2001.
- [ 
- %a{ :href => "http://bioinformatics.oupjournals.org/cgi/reprint/17/1/107.pdf" }
- \.pdf
- \ ]
- %dt
- [
- %a{ :name => "kramer01e" }
- 25
- ]
- %dd
- S. Kramer, L. De Raedt, and C. Helma.
- Molecular feature mining in HIV data.
- In
- %em
- Proceedings of the Seventh ACM SIGKDD International
- Conference on Knowledge Discovery and Data Mining (KDD-01)
- , pages 136-143,
- 2001.
- %dt
- [
- %a{ :name => "helma00a" }
- 26
- ]
- %dd
- C. Helma, S. Kramer, B. Pfahringer, and E. Gottmann.
- Data quality in predictive toxicology: Identification of chemical
- structures and calculation of chemical properties.
- %em
- Environ. Health Perspect.
- , 108:1029-1033, 2000.
- [ 
- %a{ :href => "http://ehpnet1.niehs.nih.gov/docs/2000/108p1029-1033helma/abstract.html" }
- \.html
- \ ]
- %dt
- [
- %a{ :name => "helma00b" }
- 27
- ]
- %dd
- C. Helma, E. Gottmann, and S. Kramer.
- Knowledge discovery and data mining in toxicology.
- %em
- Stat Methods Med Res.
- , 9:329-358, 2000.
- [ 
- %a{ :href => "http://www.in-silico.de/articles/smmr.pdf" }
- \.pdf
- \ ]
- %dt
- [
- %a{ :name => "helma00c" }
- 28
- ]
- %dd
- C. Helma, S. Kramer, and B. Pfahringer.
- Carcinogenicity prediction for noncongeneric compounds: Experiments
- with the Machine Learning Program SRT and various sets of chemical
- descriptors.
- In
- %em
- Molecular Modelling and Prediction of Bioactivity
- , page 464,
- 2000.
- %dt
- [
- %a{ :name => "helma00d" }
- 29
- ]
- %dd
- C. Helma and M. Uhl.
- A public domain image analysis program for the single cell gel
- electrophoresis (comet) assay.
- %em
- Mutation Res.
- , 466:9-15, 2000.
- [ 
- %a{ :href => "http://www.in-silico.de/articles/comet.pdf" }
- \.pdf
- \ ]
- %dt
- [
- %a{ :name => "helma00e" }
- 30
- ]
- %dd
- C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
- The application of machine learning algorithms to detect chemical
- properties responsible for carcinogenicity.
- In K. Gundertofte and F.S. Jorgensen, editors,
- %em
- Molecular
- Modeling and Prediction of Bioactivity
- , pages 464-466, New York, 2000.
- Kluwer Academic/Plenum Publishers.
- %dt
- [
- %a{ :name => "helma00f" }
- 31
- ]
- %dd
- C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
- Artificial Intelligence Methoden zur Vorhersage der
- Kanzerogenität organischer Verbindungen.
- In H. Schöffl, H. Spielmann, and H.A. Tritthart, editors,
- %em
- Ersatz- und Ergänzungsmethoden zu Tierversuchen: Forschung ohne
- Tierversuche
- , pages 128-134, Wien-New York, 2000. Springer Verlag.
- %dt
- [
- %a{ :name => "uhl00" }
- 32
- ]
- %dd
- M. Uhl, C. Helma, and S. Knasmüller.
- Evaluation of the single cell gel electrophoretic assay with human
- hepatoma (HepG2) cells.
- %em
- Mutation Res.
- , 468:213-225, 2000.
- %dt
- [
- %a{ :name => "helma99a" }
- 33
- ]
- %dd
- C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
- Data quality issues in toxicological knowledge discovery.
- In
- %em
- Predictive Toxicology of Chemicals: Experiences and Impact of
- AI Tools
- , pages 8-11, Menlo Park, California, 1999. AAAI Press.
- %dt
- [
- %a{ :name => "pfahringer99" }
- 34
- ]
- %dd
- B. Pfahringer, E. Gottmann, C. Helma, and S. Kramer.
- Efficiency/representational issues in toxicological knowledge
- discovery.
- In
- %em
- Predictive Toxicology of Chemicals: Experiences and Impact of
- AI Tools
- , pages 86-89, Menlo Park, California, 1999. AAAI Press.
- %dt
- [
- %a{ :name => "uhl99" }
- 35
- ]
- %dd
- M. Uhl, C. Helma, and S. Knasmüller.
- Single-cell gel electrophoresis assays with human-derived hepatoma
- (HepG2) cells.
- %em
- Mutation Res.
- , 441:215-224, 1999.
- %dt
- [
- %a{ :name => "helma98a" }
- 36
- ]
- %dd
- C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
- The application of machine learning algorithms to detect chemical
- properties responsible for carcinogenicity.
- In
- %em
- Molecular Modelling and Prediction of Bioactivity.
- Proceedings of the 12th European Symposium on Quantitative Structure-Activity
- Relationships
- , 1998.
- %dt
- [
- %a{ :name => "helma98b" }
- 37
- ]
- %dd
- C. Helma, P. Eckl, E. Gottmann, F. Kassie, W. Rodinger, H. Steinkellner,
- C. Windpassinger, R. Schulte-Hermann, and S. Knasmüller.
- Genotoxic and ecotoxic effects of groundwaters and their relation to
- routinely measured chemical parameters.
- %em
- Environ. Sci. Technol.
- , 32:1799-1805, 1998.
- %dt
- [
- %a{ :name => "knasmueller98" }
- 38
- ]
- %dd
- S. Knasmüller, C. Helma, P. Eckl, E. Gottmann, H. Steinkellner, F. Kassie,
- T. Haider, W. Parzefall, and R. Schulte-Hermann.
- Investigations on genotoxic effects of groundwater from the
- Mitterndorfer Senke from the vicinity of Wiener Neustadt.
- %em
- Wiener Klinische Wochenschrift
- , 110:824-833, 1998.
- %dt
- [
- %a{ :name => "kramer98" }
- 39
- ]
- %dd
- S. Kramer, B. Pfahringer, and C. Helma.
- Stochastic propositionalization of non-determinate background
- knowledge.
- In
- %em
- Proceedings of the 8th International Workshop on Inductive
- Logic Programming (ILP-98)
- , pages 80-94, Berlin Heidelberg New York, 1998.
- Springer.
- %dt
- [
- %a{ :name => "steinkellner98" }
- 40
- ]
- %dd
- H. Steinkellner, M.S. Kong, C. Helma, S. Ecker, T.H. Ma, O. Horak, M. Kundi,
- and S. Knasmüller.
- Genotoxic effects of heavy metals: Comparative investigation with
- plant bioassays.
- %em
- Environ. Mol. Mutagen.
- , 31:183-191, 1998.
- %dt
- [
- %a{ :name => "helma97a" }
- 41
- ]
- %dd
- C. Helma and S. Knasmüller.
- Die Belastung von Gewässern mit gentoxischen Substanzen
- IIa: Die Quellen gentoxischer Kontaminationen (Industrielle
- Emissionen).
- %em
- UWSF-Z.Umweltchem.Ökotox.
- , 9:41-48, 1997.
- %dt
- [
- %a{ :name => "helma97b" }
- 42
- ]
- %dd
- C. Helma and S. Knasmüller.
- Die Belastung von Gewässern mit gentoxischen Substanzen
- IIb: Die Quellen gentoxischer Kontaminationen (Nichtindustrielle
- Emissionen).
- %em
- UWSF-Z.Umweltchem.Ökotox.
- , 9:163-168, 1997.
- %dt
- [
- %a{ :name => "helma97c" }
- 43
- ]
- %dd
- C. Helma.
- Die Situation der Chlorchemie in Östereich: Chlorhältige
- Pflanzenschutz- Holzschutz und Wasserdesinfektionsmittel - Entwicklungen im
- Zeitraum 1993 bis 1997.
- Technical report, Gesellschaft Österreichischer Chemiker, 1997.
- %dt
- [
- %a{ :name => "knasmueller97" }
- 44
- ]
- %dd
- S. Knasmüller, W. Parzefall, C. Helma, F. Kassie, S. Ecker, and
- R. Schulte-Hermann.
- Toxic effects of griseofulvin: Disease models, mechanisms, and risk
- assessment.
- %em
- Critical Reviews in Toxicology
- , 27:495-537, 1997.
- %dt
- [
- %a{ :name => "kramer97a" }
- 45
- ]
- %dd
- S. Kramer, B. Pfahringer, and C. Helma.
- Mining for causes of cancer: Machine learning experiments at various
- levels of detail.
- In
- %em
- Proceedings of the Third International Conference on
- Knowledge Discovery and Data Mining (KDD-97)
- , Menlo Park, CA, 1997. AAAI
- Press.
- %dt
- [
- %a{ :name => "helma96a" }
- 46
- ]
- %dd
- C. Helma, V. Mersch-Sundermann, V.S. Houk, U. Glasbrenner, C. Klein,
- L. Wenquing, K. Fekadu, R. Schulte-Hermann, and S. Knasmüller.
- Comparative evaluation of four bacterial assays for the detection of
- genotoxic effects in water samples.
- %em
- Environ. Sci. Technol.
- , 30:897-907, 1996.
- %dt
- [
- %a{ :name => "helma95" }
- 47
- ]
- %dd
- C. Helma, L. Kronberg, T.H. Ma, and S. Knasmüller.
- Genotoxic effects of the chlorinated hydroxyfuranones
- 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone and
- 3,4-dichloro-5-hydroxy-2[5H]-furanone in
- %i
- Tradescantia
- micronucleus assays.
- %em
- Mutation Res.
- , 346:181-186, 1995.
- %dt
- [
- %a{ :name => "helma95b" }
- 48
- ]
- %dd
- C. Helma.
- Erfahrungen mit dem Einsatz biologischer Mutationstests zur
- Verfahrensoptimierung und Umweltkontrolle.
- In
- %em
- Handbuch der Umwelttechnik 1995
- , pages 266-267. Wien, 1995.
- %dt
- [
- %a{ :name => "helma95c" }
- 49
- ]
- %dd
- C. Helma.
- Detection of genotoxic contaminations in water.
- In M. Guminska and J. Miedzobrodzki, editors,
- %em
- Molecular Biology
- for Environment and Man
- , pages 99-111. 1995.
- %dt
- [
- %a{ :name => "helma94a" }
- 50
- ]
- %dd
- C. Helma, R. Sommer, R. Schulte-Hermann, and S. Knasmüller.
- Enhanced clastogenicity of contaminated ground water following UV
- irradiation detected by the
- %em
- Tradescantia
- micronucleus assay.
- %em
- Mutation Res.
- , 323:93-98, 1994.
- %dt
- [
- %a{ :name => "helma94b" }
- 51
- ]
- %dd
- C. Helma, S. Knasmüller, and R. Schulte-Hermann.
- Die Belastung von Wässern mit gentoxischen Substanzen I. Methoden
- zur Prüfung der Gentoxizität.
- %em
- UWSF-Z.Umweltchem.Ökotox.
- , 6:277-288, 1994.
- %dt
- [
- %a{ :name => "helma94c" }
- 52
- ]
- %dd
- C. Helma, S. Knasmüller, and R. Schulte-Hermann.
- Biologische Tests zur Prüfung der Gentoxizität:
- Einsatzmöglichkeiten zur Verfahrensoptimierung und Emissionskontrolle.
- In Brandl et al., editor,
- %em
- Ecoinforma 94. Bd 9, Kanzerogenese
- durch Umweltchemikalien
- , pages 497-512. Wien, 1994.
- %dt
- [
- %a{ :name => "fassold93" }
- 53
- ]
- %dd
- E. Fassold, C. Helma, S. Knasmüller, and R. Sattelberger.
- Die Situation der Chlorchemie in Östereich, 8. Teil:
- Chlorhältige Pflanzenschutz- Holzschutz und Wasserdesinfektionsmittel.
- Technical report, Gesellschaft Österreichischer Chemiker, 1993.
- %dt
- [
- %a{ :name => "helma92" }
- 54
- ]
- %dd
- C. Helma et.al.
- Abfallarme Großküche.
- Technical report, Österreichisches Ökologie Institut, 1992.
- %dt
- [
- %a{ :name => "helma91" }
- 55
- ]
- %dd
- C. Helma et.al.
- Ausstieg aus der Müllverbrennung.
- Technical report, Österreichisches Ökologie Institut, 1991.
+%dt
+ [
+ %a{:name => "suenderhof10"}> 1
+ ]
+%dd
+ Claudia Suenderhauf, Felix Hammann, Andreas Maunz, Christoph Helma, and Jo¿rg
+ Huwyler.
+ Combinatorial qsar modeling of human intestinal absorption.
+ = succeed "," do
+ %em Molecular Pharmaceutics
+ 8(1):213-224, 2011.
+ [ 
+ %a{:href => "http://dx.doi.org/10.1021/mp100279d"}> DOI
+ \ |
+ %a{:href => "http://pubs.acs.org/doi/abs/10.1021/mp100279d"} http
+  ]
+%dt
+ [
+ %a{:name => "maunz10a"}> 2
+ ]
+%dd
+ Andreas Maunz, Christoph Helma, and Stefan Kramer.
+ Efficient mining for structurally diverse subgraph patterns in large
+ molecular databases.
+ = succeed "," do
+ %em Machine Learning
+ pages 1-26, 2010.
+ [ 
+ %a{:href => "http://dx.doi.org/10.1007/s10994-010-5187-6"}> http
+ \ ]
+%dt
+ [
+ %a{:name => "hardy10"}> 3
+ ]
+%dd
+ Barry Hardy, Nicki Douglas, Christoph Helma, Micha Rautenberg, Nina Jeliazkova,
+ Vedrin Jeliazkov, Ivelina Nikolova, Romualdo Benigni, Olga Tcheremenskaia,
+ Stefan Kramer, Tobias Girschick, Fabian Buchwald, Joerg Wicker, Andreas
+ Karwath, Martin Gutlein, Andreas Maunz, Haralambos Sarimveis, Georgia
+ Melagraki, Antreas Afantitis, Pantelis Sopasakis, David Gallagher, Vladimir
+ Poroikov, Dmitry Filimonov, Alexey Zakharov, Alexey Lagunin, Tatyana
+ Gloriozova, Sergey Novikov, Natalia Skvortsova, Dmitry Druzhilovsky, Sunil
+ Chawla, Indira Ghosh, Surajit Ray, Hitesh Patel, and Sylvia Escher.
+ Collaborative development of predictive toxicology applications.
+ = succeed "," do
+ %em Journal of Cheminformatics
+ 2:7, 2010.
+%dt
+ [
+ %a{:name => "maunz08b"}> 4
+ ]
+%dd
+ A. Maunz and C. Helma.
+ Prediction of toxic effects of pharmaceutical agents.
+ In K. V. Balakin, editor,
+ = succeed "," do
+ %em
+ Pharmaceutical Data Mining: Approaches
+ and Applications for Drug Discovery
+ New York, 2009. J. Wiley & Sons, Inc.
+ [ 
+ %a{:href => "http://www.in-silico.de/articles/chapter_mh.pdf"}> .pdf
+ \ ]
+%dt
+ [
+ %a{:name => "maunz09a"}> 5
+ ]
+%dd
+ A. Maunz, C. Helma, and S. Kramer.
+ Large-scale graph mining using backbone refinement classes.
+ In
+ = succeed "," do
+ %em
+ Proceedings of the 15th ACM SIGKDD International Conference
+ on Knowledge Discovery and Data Mining (KDD-09)
+ page in press, 2009.
+ [ 
+ %a{:href => "http://www.maunz.de/ls_graph_mining_using_bbrcs.pdf"}> .pdf
+ \ ]
+%dt
+ [
+ %a{:name => "hammann09a"}> 6
+ ]
+%dd
+ F. Hammann, H. Gutmann, U. Jecklin, A. Maunz, C. Helma, and J. Drewe.
+ Development of decision tree models for substrates, inhibitors and
+ inducers of P-glycoprotein.
+ = succeed "," do
+ %em Current Drug Metabolism
+ 10:339-46, 2009.
+%dt
+ [
+ %a{:name => "hammann09b"}> 7
+ ]
+%dd
+ Felix Hammann, Heike Gutmann, Ulli Baumann, Christoph Helma, and Juergen Drewe.
+ Classification of cytochrome p(450) activities using machine learning
+ methods.
+ = succeed "," do
+ %em Molecular pharmaceutics
+ 6:1920-6, 2009.
+%dt
+ [
+ %a{:name => "maunz08a"}> 8
+ ]
+%dd
+ A. Maunz and C. Helma.
+ Prediction of chemical toxicity with local support vector regression
+ and activity-specific kernels.
+ = succeed "," do
+ %em SAR QSAR Environ. Res.
+ 19:413-431, 2008.
+ [ 
+ %a{:href => "http://www.in-silico.de/articles/mh_tf.pdf"}> .pdf
+ \ ]
+%dt
+ [
+ %a{:name => "benigni07"}> 9
+ ]
+%dd
+ R. Benigni, T. I. Netzeva, E. Benfenati, C. Bossa, R. Franke, C. Helma,
+ E. Hulzebos, C. Marchant, A. Richard, Y.-T. Woo, and C. Yang.
+ The expanding role of predictive toxicology: an update on the (Q)SAR
+ models for mutagens and carcinogens.
+ = succeed "," do
+ %em J Environ Sci Health C Environ Carcinog Ecotoxicol Rev.
+ 25:53-97, 2007.
+%dt
+ [
+ %a{:name => "helma06a"}> 10
+ ]
+%dd
+ C. Helma.
+ Lazy structure-activity relationships (
+ %tt> lazar
+ ) for the
+ prediction of rodent carcinogenicity and
+ %em Salmonella
+ mutagenicity.
+ = succeed "," do
+ %em Molecular Diversity
+ 10:147-158, 2006.
+ [ 
+ %a{:href => "http://www.in-silico.de/articles/modi020905.pdf"}> .pdf
+ \ ]
+%dt
+ [
+ %a{:name => "helma06b"}> 11
+ ]
+%dd
+ C. Helma and J. Kazius.
+ Artificial intelligence and data mining for toxicity prediction.
+ = succeed "," do
+ %em Current Computer-Aided Drug Design
+ 2:1-19, 2006.
+ [ 
+ %a{:href => "http://www.in-silico.de/articles/helma_kazius_ccadd.pdf"}> .pdf
+ \ ]
+%dt
+ [
+ %a{:name => "vracko06"}> 12
+ ]
+%dd
+ M. Vracko, V. Bandelj, P. Barbieri, E. Benfenati, Q. Chaudhry, M. Cronin,
+ J. Devillers, A. Gallegos, G. Gini, P. Gramatica, C. Helma, D. Neagu,
+ T. Netzeva, M. Pavan, G. Patlevicz, M. Randic, I. Tsakovska, and A. Worth.
+ Validation of counter propagation neural network models for
+ predictive toxicology according to the OECD principles. A case study.
+ = succeed "," do
+ %em SAR QSAR Environ. Res.
+ 17:265-84, 2006.
+%dt
+ [
+ %a{:name => "helma05a"}> 13
+ ]
+%dd
+ C. Helma.
+ = succeed "." do
+ %em Predictive Toxicology
+ CRC Press, Boca Raton, 2005.
+%dt
+ [
+ %a{:name => "helma05b"}> 14
+ ]
+%dd
+ C. Helma.
+ %tt lazar:
+ Lazy Structure - Activity Relationships for toxicity
+ prediction.
+ In C. Helma, editor,
+ = succeed "," do
+ %em Predictive Toxicology
+ pages 479-499. CRC
+ Press, Boca Raton, 2005.
+%dt
+ [
+ %a{:name => "helma05c"}> 15
+ ]
+%dd
+ C. Helma.
+ %em In Silico
+ predictive toxicology: The state-of-the-art and
+ strategies to predict human health effects.
+ = succeed "," do
+ %em Current Opinions in Drug Discovery & Development
+ 8:27-31,
+ 2005.
+ [ 
+ %a{:href => "http://www.in-silico.de/articles/helma_coddd.pdf"}> .pdf
+ \ ]
+%dt
+ [
+ %a{:name => "helma05d"}> 16
+ ]
+%dd
+ C. Helma.
+ A brief introduction to predictive toxicology.
+ In C. Helma, editor,
+ = succeed "." do
+ %em Predictive Toxicology
+ CRC Press, Boca
+ Raton, 2005.
+%dt
+ [
+ %a{:name => "kramer05"}> 17
+ ]
+%dd
+ S. Kramer and C. Helma.
+ Machine learning and data mining.
+ In C. Helma, editor,
+ = succeed "," do
+ %em Predictive Toxicology
+ pages 223-254. CRC
+ Press, Boca Raton, 2005.
+%dt
+ [
+ %a{:name => "helma04a"}> 18
+ ]
+%dd
+ C. Helma, T. Kramer, S. Kramer, and L. DeRaedt.
+ Data Mining and Machine Learning techniques for the
+ identification of mutagenicity inducing substructures and
+ Structure-Activity Relationships of noncongeneric compounds.
+ = succeed "," do
+ %em J. Chem. Inf. Comput. Sci.
+ 44:1402-1411, 2004.
+ [ 
+ %a{:href => "http://pubs3.acs.org/acs/journals/doilookup?in_doi=10.1021/ci034254q"}> http
+ \ ]
+%dt
+ [
+ %a{:name => "helma04b"}> 19
+ ]
+%dd
+ C. Helma.
+ Data mining and knowledge discovery in predictive toxicology.
+ = succeed "," do
+ %em SAR QSAR Environ. Res.
+ 15:367-383, 2004.
+%dt
+ [
+ %a{:name => "helma03a"}> 20
+ ]
+%dd
+ C. Helma and S. Kramer.
+ A survey of the Predictive Toxicology Challenge.
+ = succeed "," do
+ %em Bioinformatics
+ 19:1179-1182, 2003.
+ [ 
+ %a{:href => "http://bioinformatics.oxfordjournals.org/cgi/content/abstract/19/10/1179"}> http
+ \ ]
+%dt
+ [
+ %a{:name => "helma03b"}> 21
+ ]
+%dd
+ C. Helma, S. Kramer, and L. DeRaedt.
+ The molecular feature miner MolFea.
+ In M. Hicks and C. Kettner, editors,
+ = succeed "," do
+ %em
+ Proceedings of the
+ Beilstein Workshop 2002: Molecular Informatics: Confronting Complexity
+ pages 79-93. Beilstein Institut, Frankfurt, 2003.
+%dt
+ [
+ %a{:name => "toivonen03"}> 22
+ ]
+%dd
+ H. Toivonen, A. Srinivasan, R. D. King, S. Kramer, and C. Helma.
+ Statistical evaluation of the Predictive Toxicology Challenge
+ 2000-2001.
+ = succeed "," do
+ %em Bioinformatics
+ 19:1183-1193, 2003.
+ [ 
+ %a{:href => "http://bioinformatics.oxfordjournals.org/cgi/content/abstract/19/10/1183"}> http
+ \ ]
+%dt
+ [
+ %a{:name => "helma02a"}> 23
+ ]
+%dd
+ C. Helma.
+ Data mining in toxicology.
+ In J.P.V. Heuvel, W.F. Greenlee, G.H. Perdew, and W.B. Mattes,
+ editors,
+ = succeed "," do
+ %em
+ Comprehensive Toxicology Vol XX. Cellular and Molecular
+ Toxicology
+ pages 611-624. Elsevier, 2002.
+%dt
+ [
+ %a{:name => "kassie02"}> 24
+ ]
+%dd
+ F. Kassie, S. Rabot, M. Uhl, W. Huber, H.M. Qin, C. Helma, R. Schulte-Hermann,
+ and S. Knasmüller.
+ Chemoprotective effects of garden cress (lepidium sativum) and its
+ constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced
+ genotoxic effects and colonicneoplastic lesions.
+ = succeed "," do
+ %em Carcinogenesis
+ 23:1155-1161, 2002.
+%dt
+ [
+ %a{:name => "kramer02"}> 25
+ ]
+%dd
+ S. Kramer, E. Frank, and C. Helma.
+ Fragment generation and Support Vector Machines for inducing
+ SARs.
+ = succeed "," do
+ %em SAR and QSAR in Environmental Research
+ 13:509-523, 2002.
+%dt
+ [
+ %a{:name => "gottmann01"}> 26
+ ]
+%dd
+ E. Gottmann, S. Kramer, B. Pfahringer, and C. Helma.
+ Data quality in predictive toxicology: Reproducibility of rodent
+ carcinogenicity experiments.
+ = succeed "," do
+ %em Environ. Health Perspect.
+ 109:509-514, 2001.
+ [ 
+ %a{:href => "http://www.ehponline.org/members/2001/109p509-514gottmann/gottmann-full.html"}> .html
+ \ ]
+%dt
+ [
+ %a{:name => "helma01b"}> 27
+ ]
+%dd
+ C. Helma, R.D. King, S. Kramer, and A. Srinivasan.
+ The Predictive Toxicology Challenge 2000-2001.
+ = succeed "," do
+ %em Bioinformatics
+ 17:107-108, 2001.
+ [ 
+ %a{:href => "http://bioinformatics.oupjournals.org/cgi/reprint/17/1/107.pdf"}> .pdf
+ \ ]
+%dt
+ [
+ %a{:name => "kramer01e"}> 28
+ ]
+%dd
+ S. Kramer, L. De Raedt, and C. Helma.
+ Molecular feature mining in HIV data.
+ In
+ = succeed "," do
+ %em
+ Proceedings of the Seventh ACM SIGKDD International
+ Conference on Knowledge Discovery and Data Mining (KDD-01)
+ pages 136-143,
+ 2001.
+%dt
+ [
+ %a{:name => "helma00a"}> 29
+ ]
+%dd
+ C. Helma, S. Kramer, B. Pfahringer, and E. Gottmann.
+ Data quality in predictive toxicology: Identification of chemical
+ structures and calculation of chemical properties.
+ = succeed "," do
+ %em Environ. Health Perspect.
+ 108:1029-1033, 2000.
+ [ 
+ %a{:href => "http://ehpnet1.niehs.nih.gov/docs/2000/108p1029-1033helma/abstract.html"}> .html
+ \ ]
+%dt
+ [
+ %a{:name => "helma00b"}> 30
+ ]
+%dd
+ C. Helma, E. Gottmann, and S. Kramer.
+ Knowledge discovery and data mining in toxicology.
+ = succeed "," do
+ %em Stat Methods Med Res.
+ 9:329-358, 2000.
+ [ 
+ %a{:href => "http://www.in-silico.de/articles/smmr.pdf"}> .pdf
+ \ ]
+%dt
+ [
+ %a{:name => "helma00c"}> 31
+ ]
+%dd
+ C. Helma, S. Kramer, and B. Pfahringer.
+ Carcinogenicity prediction for noncongeneric compounds: Experiments
+ with the Machine Learning Program SRT and various sets of chemical
+ descriptors.
+ In
+ = succeed "," do
+ %em Molecular Modelling and Prediction of Bioactivity
+ page 464,
+ 2000.
+%dt
+ [
+ %a{:name => "helma00d"}> 32
+ ]
+%dd
+ C. Helma and M. Uhl.
+ A public domain image analysis program for the single cell gel
+ electrophoresis (comet) assay.
+ = succeed "," do
+ %em Mutation Res.
+ 466:9-15, 2000.
+ [ 
+ %a{:href => "http://www.in-silico.de/articles/comet.pdf"}> .pdf
+ \ ]
+%dt
+ [
+ %a{:name => "helma00e"}> 33
+ ]
+%dd
+ C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
+ The application of machine learning algorithms to detect chemical
+ properties responsible for carcinogenicity.
+ In K. Gundertofte and F.S. Jorgensen, editors,
+ = succeed "," do
+ %em
+ Molecular
+ Modeling and Prediction of Bioactivity
+ pages 464-466, New York, 2000.
+ Kluwer Academic/Plenum Publishers.
+%dt
+ [
+ %a{:name => "helma00f"}> 34
+ ]
+%dd
+ C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
+ Artificial Intelligence Methoden zur Vorhersage der
+ Kanzerogenität organischer Verbindungen.
+ In H. Schöffl, H. Spielmann, and H.A. Tritthart, editors,
+ = succeed "," do
+ %em
+ Ersatz- und Ergänzungsmethoden zu Tierversuchen: Forschung ohne
+ Tierversuche
+ pages 128-134, Wien-New York, 2000. Springer Verlag.
+%dt
+ [
+ %a{:name => "uhl00"}> 35
+ ]
+%dd
+ M. Uhl, C. Helma, and S. Knasmüller.
+ Evaluation of the single cell gel electrophoretic assay with human
+ hepatoma (HepG2) cells.
+ = succeed "," do
+ %em Mutation Res.
+ 468:213-225, 2000.
+%dt
+ [
+ %a{:name => "helma99a"}> 36
+ ]
+%dd
+ C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
+ Data quality issues in toxicological knowledge discovery.
+ In
+ = succeed "," do
+ %em
+ Predictive Toxicology of Chemicals: Experiences and Impact of
+ AI Tools
+ pages 8-11, Menlo Park, California, 1999. AAAI Press.
+%dt
+ [
+ %a{:name => "pfahringer99"}> 37
+ ]
+%dd
+ B. Pfahringer, E. Gottmann, C. Helma, and S. Kramer.
+ Efficiency/representational issues in toxicological knowledge
+ discovery.
+ In
+ = succeed "," do
+ %em
+ Predictive Toxicology of Chemicals: Experiences and Impact of
+ AI Tools
+ pages 86-89, Menlo Park, California, 1999. AAAI Press.
+%dt
+ [
+ %a{:name => "uhl99"}> 38
+ ]
+%dd
+ M. Uhl, C. Helma, and S. Knasmüller.
+ Single-cell gel electrophoresis assays with human-derived hepatoma
+ (HepG2) cells.
+ = succeed "," do
+ %em Mutation Res.
+ 441:215-224, 1999.
+%dt
+ [
+ %a{:name => "helma98a"}> 39
+ ]
+%dd
+ C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
+ The application of machine learning algorithms to detect chemical
+ properties responsible for carcinogenicity.
+ In
+ = succeed "," do
+ %em
+ Molecular Modelling and Prediction of Bioactivity.
+ Proceedings of the 12th European Symposium on Quantitative Structure-Activity
+ Relationships
+ 1998.
+%dt
+ [
+ %a{:name => "helma98b"}> 40
+ ]
+%dd
+ C. Helma, P. Eckl, E. Gottmann, F. Kassie, W. Rodinger, H. Steinkellner,
+ C. Windpassinger, R. Schulte-Hermann, and S. Knasmüller.
+ Genotoxic and ecotoxic effects of groundwaters and their relation to
+ routinely measured chemical parameters.
+ = succeed "," do
+ %em Environ. Sci. Technol.
+ 32:1799-1805, 1998.
+%dt
+ [
+ %a{:name => "knasmueller98"}> 41
+ ]
+%dd
+ S. Knasmüller, C. Helma, P. Eckl, E. Gottmann, H. Steinkellner, F. Kassie,
+ T. Haider, W. Parzefall, and R. Schulte-Hermann.
+ Investigations on genotoxic effects of groundwater from the
+ Mitterndorfer Senke from the vicinity of Wiener Neustadt.
+ = succeed "," do
+ %em Wiener Klinische Wochenschrift
+ 110:824-833, 1998.
+%dt
+ [
+ %a{:name => "kramer98"}> 42
+ ]
+%dd
+ S. Kramer, B. Pfahringer, and C. Helma.
+ Stochastic propositionalization of non-determinate background
+ knowledge.
+ In
+ = succeed "," do
+ %em
+ Proceedings of the 8th International Workshop on Inductive
+ Logic Programming (ILP-98)
+ pages 80-94, Berlin Heidelberg New York, 1998.
+ Springer.
+%dt
+ [
+ %a{:name => "steinkellner98"}> 43
+ ]
+%dd
+ H. Steinkellner, M.S. Kong, C. Helma, S. Ecker, T.H. Ma, O. Horak, M. Kundi,
+ and S. Knasmüller.
+ Genotoxic effects of heavy metals: Comparative investigation with
+ plant bioassays.
+ = succeed "," do
+ %em Environ. Mol. Mutagen.
+ 31:183-191, 1998.
+%dt
+ [
+ %a{:name => "helma97a"}> 44
+ ]
+%dd
+ C. Helma and S. Knasmüller.
+ Die Belastung von Gewässern mit gentoxischen Substanzen
+ IIa: Die Quellen gentoxischer Kontaminationen (Industrielle
+ Emissionen).
+ = succeed "," do
+ %em UWSF-Z.Umweltchem.Ökotox.
+ 9:41-48, 1997.
+%dt
+ [
+ %a{:name => "helma97b"}> 45
+ ]
+%dd
+ C. Helma and S. Knasmüller.
+ Die Belastung von Gewässern mit gentoxischen Substanzen
+ IIb: Die Quellen gentoxischer Kontaminationen (Nichtindustrielle
+ Emissionen).
+ = succeed "," do
+ %em UWSF-Z.Umweltchem.Ökotox.
+ 9:163-168, 1997.
+%dt
+ [
+ %a{:name => "helma97c"}> 46
+ ]
+%dd
+ C. Helma.
+ Die Situation der Chlorchemie in Östereich: Chlorhältige
+ Pflanzenschutz- Holzschutz und Wasserdesinfektionsmittel - Entwicklungen im
+ Zeitraum 1993 bis 1997.
+ Technical report, Gesellschaft Österreichischer Chemiker, 1997.
+%dt
+ [
+ %a{:name => "knasmueller97"}> 47
+ ]
+%dd
+ S. Knasmüller, W. Parzefall, C. Helma, F. Kassie, S. Ecker, and
+ R. Schulte-Hermann.
+ Toxic effects of griseofulvin: Disease models, mechanisms, and risk
+ assessment.
+ = succeed "," do
+ %em Critical Reviews in Toxicology
+ 27:495-537, 1997.
+%dt
+ [
+ %a{:name => "kramer97a"}> 48
+ ]
+%dd
+ S. Kramer, B. Pfahringer, and C. Helma.
+ Mining for causes of cancer: Machine learning experiments at various
+ levels of detail.
+ In
+ = succeed "," do
+ %em
+ Proceedings of the Third International Conference on
+ Knowledge Discovery and Data Mining (KDD-97)
+ Menlo Park, CA, 1997. AAAI
+ Press.
+%dt
+ [
+ %a{:name => "helma96a"}> 49
+ ]
+%dd
+ C. Helma, V. Mersch-Sundermann, V.S. Houk, U. Glasbrenner, C. Klein,
+ L. Wenquing, K. Fekadu, R. Schulte-Hermann, and S. Knasmüller.
+ Comparative evaluation of four bacterial assays for the detection of
+ genotoxic effects in water samples.
+ = succeed "," do
+ %em Environ. Sci. Technol.
+ 30:897-907, 1996.
+%dt
+ [
+ %a{:name => "helma95"}> 50
+ ]
+%dd
+ C. Helma, L. Kronberg, T.H. Ma, and S. Knasmüller.
+ Genotoxic effects of the chlorinated hydroxyfuranones
+ 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone and
+ 3,4-dichloro-5-hydroxy-2[5H]-furanone in
+ %i Tradescantia
+ micronucleus assays.
+ = succeed "," do
+ %em Mutation Res.
+ 346:181-186, 1995.
+%dt
+ [
+ %a{:name => "helma95b"}> 51
+ ]
+%dd
+ C. Helma.
+ Erfahrungen mit dem Einsatz biologischer Mutationstests zur
+ Verfahrensoptimierung und Umweltkontrolle.
+ In
+ = succeed "," do
+ %em Handbuch der Umwelttechnik 1995
+ pages 266-267. Wien, 1995.
+%dt
+ [
+ %a{:name => "helma95c"}> 52
+ ]
+%dd
+ C. Helma.
+ Detection of genotoxic contaminations in water.
+ In M. Guminska and J. Miedzobrodzki, editors,
+ = succeed "," do
+ %em
+ Molecular Biology
+ for Environment and Man
+ pages 99-111. 1995.
+%dt
+ [
+ %a{:name => "helma94a"}> 53
+ ]
+%dd
+ C. Helma, R. Sommer, R. Schulte-Hermann, and S. Knasmüller.
+ Enhanced clastogenicity of contaminated ground water following UV
+ irradiation detected by the
+ %em Tradescantia
+ micronucleus assay.
+ = succeed "," do
+ %em Mutation Res.
+ 323:93-98, 1994.
+%dt
+ [
+ %a{:name => "helma94b"}> 54
+ ]
+%dd
+ C. Helma, S. Knasmüller, and R. Schulte-Hermann.
+ Die Belastung von Wässern mit gentoxischen Substanzen I. Methoden
+ zur Prüfung der Gentoxizität.
+ = succeed "," do
+ %em UWSF-Z.Umweltchem.Ökotox.
+ 6:277-288, 1994.
+%dt
+ [
+ %a{:name => "helma94c"}> 55
+ ]
+%dd
+ C. Helma, S. Knasmüller, and R. Schulte-Hermann.
+ Biologische Tests zur Prüfung der Gentoxizität:
+ Einsatzmöglichkeiten zur Verfahrensoptimierung und Emissionskontrolle.
+ In Brandl et al., editor,
+ = succeed "," do
+ %em
+ Ecoinforma 94. Bd 9, Kanzerogenese
+ durch Umweltchemikalien
+ pages 497-512. Wien, 1994.
+%dt
+ [
+ %a{:name => "fassold93"}> 56
+ ]
+%dd
+ E. Fassold, C. Helma, S. Knasmüller, and R. Sattelberger.
+ Die Situation der Chlorchemie in Östereich, 8. Teil:
+ Chlorhältige Pflanzenschutz- Holzschutz und Wasserdesinfektionsmittel.
+ Technical report, Gesellschaft Österreichischer Chemiker, 1993.
+%dt
+ [
+ %a{:name => "helma92"}> 57
+ ]
+%dd
+ C. Helma et.al.
+ Abfallarme Großküche.
+ Technical report, Österreichisches Ökologie Institut, 1992.
+%dt
+ [
+ %a{:name => "helma91"}> 58
+ ]
+%dd
+ C. Helma et.al.
+ Ausstieg aus der Müllverbrennung.
+ Technical report, Österreichisches Ökologie Institut, 1991.