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-!!!
-%html
- %head
- %title helma
- %body
- /
- This document was automatically generated with bibtex2html 1.96
- (see http://www.lri.fr/~filliatr/bibtex2html/),
- with the following command:
- bibtex2html -r -d -dl -nobibsource -nofooter helma.bib
- %dl
- %dt
- [
- %a{:name => "suenderhof10"}> 1
- ]
- %dd
- Claudia Suenderhauf, Felix Hammann, Andreas Maunz, Christoph Helma, and Jorg
- Huwyler.
- Combinatorial qsar modeling of human intestinal absorption.
- = succeed "," do
- %em Molecular Pharmaceutics
- 8(1):213-224, 2011.
- [ 
- %a{:href => "http://dx.doi.org/10.1021/mp100279d"}> DOI
-  |
- = succeed " |" do
- %a{:href => "http://arxiv.org/abs/http://pubs.acs.org/doi/pdf/10.1021/mp100279d"} arXiv
- = succeed " ]" do
- %a{:href => "http://pubs.acs.org/doi/abs/10.1021/mp100279d"} http
- %dt
- [
- %a{:name => "maunz10a"}> 2
- ]
- %dd
- Andreas Maunz, Christoph Helma, and Stefan Kramer.
- Efficient mining for structurally diverse subgraph patterns in large
- molecular databases.
- = succeed "," do
- %em Machine Learning
- pages 1-26, 2010.
- [ 
- %a{:href => "http://dx.doi.org/10.1007/s10994-010-5187-6"}> http
- \ ]
- %dt
- [
- %a{:name => "hardy10"}> 3
- ]
- %dd
- Barry Hardy, Nicki Douglas, Christoph Helma, Micha Rautenberg, Nina Jeliazkova,
- Vedrin Jeliazkov, Ivelina Nikolova, Romualdo Benigni, Olga Tcheremenskaia,
- Stefan Kramer, Tobias Girschick, Fabian Buchwald, Joerg Wicker, Andreas
- Karwath, Martin Gutlein, Andreas Maunz, Haralambos Sarimveis, Georgia
- Melagraki, Antreas Afantitis, Pantelis Sopasakis, David Gallagher, Vladimir
- Poroikov, Dmitry Filimonov, Alexey Zakharov, Alexey Lagunin, Tatyana
- Gloriozova, Sergey Novikov, Natalia Skvortsova, Dmitry Druzhilovsky, Sunil
- Chawla, Indira Ghosh, Surajit Ray, Hitesh Patel, and Sylvia Escher.
- Collaborative development of predictive toxicology applications.
- = succeed "," do
- %em Journal of Cheminformatics
- 2:7, 2010.
- [ 
- %a{:href => "http://www.jcheminf.com/content/2/1/7"}> http
- \ ]
- %dt
- [
- %a{:name => "maunz08b"}> 4
- ]
- %dd
- A. Maunz and C. Helma.
- Prediction of toxic effects of pharmaceutical agents.
- In K. V. Balakin, editor,
- = succeed "," do
- %em
- Pharmaceutical Data Mining: Approaches
- and Applications for Drug Discovery
- New York, 2009. J. Wiley & Sons, Inc.
- [ 
- %a{:href => "http://www.in-silico.de/articles/chapter_mh.pdf"}> .pdf
- \ ]
- %dt
- [
- %a{:name => "maunz09a"}> 5
- ]
- %dd
- A. Maunz, C. Helma, and S. Kramer.
- Large-scale graph mining using backbone refinement classes.
- In
- = succeed "," do
- %em
- Proceedings of the 15th ACM SIGKDD International Conference
- on Knowledge Discovery and Data Mining (KDD-09)
- page in press, 2009.
- [ 
- %a{:href => "http://www.maunz.de/ls_graph_mining_using_bbrcs.pdf"}> .pdf
- \ ]
- %dt
- [
- %a{:name => "hammann09a"}> 6
- ]
- %dd
- F. Hammann, H. Gutmann, U. Jecklin, A. Maunz, C. Helma, and J. Drewe.
- Development of decision tree models for substrates, inhibitors and
- inducers of P-glycoprotein.
- = succeed "," do
- %em Current Drug Metabolism
- 10:339-46, 2009.
- %dt
- [
- %a{:name => "hammann09b"}> 7
- ]
- %dd
- Felix Hammann, Heike Gutmann, Ulli Baumann, Christoph Helma, and Juergen Drewe.
- Classification of cytochrome p(450) activities using machine learning
- methods.
- = succeed "," do
- %em Molecular pharmaceutics
- 6:1920-6, 2009.
- %dt
- [
- %a{:name => "maunz08a"}> 8
- ]
- %dd
- A. Maunz and C. Helma.
- Prediction of chemical toxicity with local support vector regression
- and activity-specific kernels.
- = succeed "," do
- %em SAR QSAR Environ. Res.
- 19:413-431, 2008.
- [ 
- %a{:href => "http://www.in-silico.de/articles/mh_tf.pdf"}> .pdf
- \ ]
- %dt
- [
- %a{:name => "benigni07"}> 9
- ]
- %dd
- R. Benigni, T. I. Netzeva, E. Benfenati, C. Bossa, R. Franke, C. Helma,
- E. Hulzebos, C. Marchant, A. Richard, Y.-T. Woo, and C. Yang.
- The expanding role of predictive toxicology: an update on the (Q)SAR
- models for mutagens and carcinogens.
- = succeed "," do
- %em J Environ Sci Health C Environ Carcinog Ecotoxicol Rev.
- 25:53-97, 2007.
- %dt
- [
- %a{:name => "helma06a"}> 10
- ]
- %dd
- C. Helma.
- Lazy structure-activity relationships (
- %tt> lazar
- ) for the
- prediction of rodent carcinogenicity and
- %em Salmonella
- mutagenicity.
- = succeed "," do
- %em Molecular Diversity
- 10:147-158, 2006.
- [ 
- %a{:href => "http://www.in-silico.de/articles/modi020905.pdf"}> .pdf
- \ ]
- %dt
- [
- %a{:name => "helma06b"}> 11
- ]
- %dd
- C. Helma and J. Kazius.
- Artificial intelligence and data mining for toxicity prediction.
- = succeed "," do
- %em Current Computer-Aided Drug Design
- 2:1-19, 2006.
- [ 
- %a{:href => "http://www.in-silico.de/articles/helma_kazius_ccadd.pdf"}> .pdf
- \ ]
- %dt
- [
- %a{:name => "vracko06"}> 12
- ]
- %dd
- M. Vracko, V. Bandelj, P. Barbieri, E. Benfenati, Q. Chaudhry, M. Cronin,
- J. Devillers, A. Gallegos, G. Gini, P. Gramatica, C. Helma, D. Neagu,
- T. Netzeva, M. Pavan, G. Patlevicz, M. Randic, I. Tsakovska, and A. Worth.
- Validation of counter propagation neural network models for
- predictive toxicology according to the OECD principles. A case study.
- = succeed "," do
- %em SAR QSAR Environ. Res.
- 17:265-84, 2006.
- %dt
- [
- %a{:name => "helma05a"}> 13
- ]
- %dd
- C. Helma.
- = succeed "." do
- %em Predictive Toxicology
- CRC Press, Boca Raton, 2005.
- %dt
- [
- %a{:name => "helma05b"}> 14
- ]
- %dd
- C. Helma.
- %tt lazar:
- Lazy Structure - Activity Relationships for toxicity
- prediction.
- In C. Helma, editor,
- = succeed "," do
- %em Predictive Toxicology
- pages 479-499. CRC
- Press, Boca Raton, 2005.
- %dt
- [
- %a{:name => "helma05c"}> 15
- ]
- %dd
- C. Helma.
- %em In Silico
- predictive toxicology: The state-of-the-art and
- strategies to predict human health effects.
- = succeed "," do
- %em Current Opinions in Drug Discovery & Development
- 8:27-31,
- 2005.
- [ 
- %a{:href => "http://www.in-silico.de/articles/helma_coddd.pdf"}> .pdf
- \ ]
- %dt
- [
- %a{:name => "helma05d"}> 16
- ]
- %dd
- C. Helma.
- A brief introduction to predictive toxicology.
- In C. Helma, editor,
- = succeed "." do
- %em Predictive Toxicology
- CRC Press, Boca
- Raton, 2005.
- %dt
- [
- %a{:name => "kramer05"}> 17
- ]
- %dd
- S. Kramer and C. Helma.
- Machine learning and data mining.
- In C. Helma, editor,
- = succeed "," do
- %em Predictive Toxicology
- pages 223-254. CRC
- Press, Boca Raton, 2005.
- %dt
- [
- %a{:name => "helma04a"}> 18
- ]
- %dd
- C. Helma, T. Kramer, S. Kramer, and L. DeRaedt.
- Data Mining and Machine Learning techniques for the
- identification of mutagenicity inducing substructures and
- Structure-Activity Relationships of noncongeneric compounds.
- = succeed "," do
- %em J. Chem. Inf. Comput. Sci.
- 44:1402-1411, 2004.
- [ 
- %a{:href => "http://pubs3.acs.org/acs/journals/doilookup?in_doi=10.1021/ci034254q"}> http
- \ ]
- %dt
- [
- %a{:name => "helma04b"}> 19
- ]
- %dd
- C. Helma.
- Data mining and knowledge discovery in predictive toxicology.
- = succeed "," do
- %em SAR QSAR Environ. Res.
- 15:367-383, 2004.
- %dt
- [
- %a{:name => "helma03a"}> 20
- ]
- %dd
- C. Helma and S. Kramer.
- A survey of the Predictive Toxicology Challenge.
- = succeed "," do
- %em Bioinformatics
- 19:1179-1182, 2003.
- [ 
- %a{:href => "http://bioinformatics.oxfordjournals.org/cgi/content/abstract/19/10/1179"}> http
- \ ]
- %dt
- [
- %a{:name => "helma03b"}> 21
- ]
- %dd
- C. Helma, S. Kramer, and L. DeRaedt.
- The molecular feature miner MolFea.
- In M. Hicks and C. Kettner, editors,
- = succeed "," do
- %em
- Proceedings of the
- Beilstein Workshop 2002: Molecular Informatics: Confronting Complexity
- pages 79-93. Beilstein Institut, Frankfurt, 2003.
- %dt
- [
- %a{:name => "toivonen03"}> 22
- ]
- %dd
- H. Toivonen, A. Srinivasan, R. D. King, S. Kramer, and C. Helma.
- Statistical evaluation of the Predictive Toxicology Challenge
- 2000-2001.
- = succeed "," do
- %em Bioinformatics
- 19:1183-1193, 2003.
- [ 
- %a{:href => "http://bioinformatics.oxfordjournals.org/cgi/content/abstract/19/10/1183"}> http
- \ ]
- %dt
- [
- %a{:name => "helma02a"}> 23
- ]
- %dd
- C. Helma.
- Data mining in toxicology.
- In J.P.V. Heuvel, W.F. Greenlee, G.H. Perdew, and W.B. Mattes,
- editors,
- = succeed "," do
- %em
- Comprehensive Toxicology Vol XX. Cellular and Molecular
- Toxicology
- pages 611-624. Elsevier, 2002.
- %dt
- [
- %a{:name => "kassie02"}> 24
- ]
- %dd
- F. Kassie, S. Rabot, M. Uhl, W. Huber, H.M. Qin, C. Helma, R. Schulte-Hermann,
- and S. Knasmüller.
- Chemoprotective effects of garden cress (lepidium sativum) and its
- constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced
- genotoxic effects and colonicneoplastic lesions.
- = succeed "," do
- %em Carcinogenesis
- 23:1155-1161, 2002.
- %dt
- [
- %a{:name => "kramer02"}> 25
- ]
- %dd
- S. Kramer, E. Frank, and C. Helma.
- Fragment generation and Support Vector Machines for inducing
- SARs.
- = succeed "," do
- %em SAR and QSAR in Environmental Research
- 13:509-523, 2002.
- %dt
- [
- %a{:name => "gottmann01"}> 26
- ]
- %dd
- E. Gottmann, S. Kramer, B. Pfahringer, and C. Helma.
- Data quality in predictive toxicology: Reproducibility of rodent
- carcinogenicity experiments.
- = succeed "," do
- %em Environ. Health Perspect.
- 109:509-514, 2001.
- [ 
- %a{:href => "http://www.ehponline.org/members/2001/109p509-514gottmann/gottmann-full.html"}> .html
- \ ]
- %dt
- [
- %a{:name => "helma01b"}> 27
- ]
- %dd
- C. Helma, R.D. King, S. Kramer, and A. Srinivasan.
- The Predictive Toxicology Challenge 2000-2001.
- = succeed "," do
- %em Bioinformatics
- 17:107-108, 2001.
- [ 
- %a{:href => "http://bioinformatics.oupjournals.org/cgi/reprint/17/1/107.pdf"}> .pdf
- \ ]
- %dt
- [
- %a{:name => "kramer01e"}> 28
- ]
- %dd
- S. Kramer, L. De Raedt, and C. Helma.
- Molecular feature mining in HIV data.
- In
- = succeed "," do
- %em
- Proceedings of the Seventh ACM SIGKDD International
- Conference on Knowledge Discovery and Data Mining (KDD-01)
- pages 136-143,
- 2001.
- %dt
- [
- %a{:name => "helma00a"}> 29
- ]
- %dd
- C. Helma, S. Kramer, B. Pfahringer, and E. Gottmann.
- Data quality in predictive toxicology: Identification of chemical
- structures and calculation of chemical properties.
- = succeed "," do
- %em Environ. Health Perspect.
- 108:1029-1033, 2000.
- [ 
- %a{:href => "http://ehpnet1.niehs.nih.gov/docs/2000/108p1029-1033helma/abstract.html"}> .html
- \ ]
- %dt
- [
- %a{:name => "helma00b"}> 30
- ]
- %dd
- C. Helma, E. Gottmann, and S. Kramer.
- Knowledge discovery and data mining in toxicology.
- = succeed "," do
- %em Stat Methods Med Res.
- 9:329-358, 2000.
- [ 
- %a{:href => "http://www.in-silico.de/articles/smmr.pdf"}> .pdf
- \ ]
- %dt
- [
- %a{:name => "helma00c"}> 31
- ]
- %dd
- C. Helma, S. Kramer, and B. Pfahringer.
- Carcinogenicity prediction for noncongeneric compounds: Experiments
- with the Machine Learning Program SRT and various sets of chemical
- descriptors.
- In
- = succeed "," do
- %em Molecular Modelling and Prediction of Bioactivity
- page 464,
- 2000.
- %dt
- [
- %a{:name => "helma00d"}> 32
- ]
- %dd
- C. Helma and M. Uhl.
- A public domain image analysis program for the single cell gel
- electrophoresis (comet) assay.
- = succeed "," do
- %em Mutation Res.
- 466:9-15, 2000.
- [ 
- %a{:href => "http://www.in-silico.de/articles/comet.pdf"}> .pdf
- \ ]
- %dt
- [
- %a{:name => "helma00e"}> 33
- ]
- %dd
- C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
- The application of machine learning algorithms to detect chemical
- properties responsible for carcinogenicity.
- In K. Gundertofte and F.S. Jorgensen, editors,
- = succeed "," do
- %em
- Molecular
- Modeling and Prediction of Bioactivity
- pages 464-466, New York, 2000.
- Kluwer Academic/Plenum Publishers.
- %dt
- [
- %a{:name => "helma00f"}> 34
- ]
- %dd
- C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
- Artificial Intelligence Methoden zur Vorhersage der
- Kanzerogenität organischer Verbindungen.
- In H. Schöffl, H. Spielmann, and H.A. Tritthart, editors,
- = succeed "," do
- %em
- Ersatz- und Ergänzungsmethoden zu Tierversuchen: Forschung ohne
- Tierversuche
- pages 128-134, Wien-New York, 2000. Springer Verlag.
- %dt
- [
- %a{:name => "uhl00"}> 35
- ]
- %dd
- M. Uhl, C. Helma, and S. Knasmüller.
- Evaluation of the single cell gel electrophoretic assay with human
- hepatoma (HepG2) cells.
- = succeed "," do
- %em Mutation Res.
- 468:213-225, 2000.
- %dt
- [
- %a{:name => "helma99a"}> 36
- ]
- %dd
- C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
- Data quality issues in toxicological knowledge discovery.
- In
- = succeed "," do
- %em
- Predictive Toxicology of Chemicals: Experiences and Impact of
- AI Tools
- pages 8-11, Menlo Park, California, 1999. AAAI Press.
- %dt
- [
- %a{:name => "pfahringer99"}> 37
- ]
- %dd
- B. Pfahringer, E. Gottmann, C. Helma, and S. Kramer.
- Efficiency/representational issues in toxicological knowledge
- discovery.
- In
- = succeed "," do
- %em
- Predictive Toxicology of Chemicals: Experiences and Impact of
- AI Tools
- pages 86-89, Menlo Park, California, 1999. AAAI Press.
- %dt
- [
- %a{:name => "uhl99"}> 38
- ]
- %dd
- M. Uhl, C. Helma, and S. Knasmüller.
- Single-cell gel electrophoresis assays with human-derived hepatoma
- (HepG2) cells.
- = succeed "," do
- %em Mutation Res.
- 441:215-224, 1999.
- %dt
- [
- %a{:name => "helma98a"}> 39
- ]
- %dd
- C. Helma, E. Gottmann, S. Kramer, and B. Pfahringer.
- The application of machine learning algorithms to detect chemical
- properties responsible for carcinogenicity.
- In
- = succeed "," do
- %em
- Molecular Modelling and Prediction of Bioactivity.
- Proceedings of the 12th European Symposium on Quantitative Structure-Activity
- Relationships
- 1998.
- %dt
- [
- %a{:name => "helma98b"}> 40
- ]
- %dd
- C. Helma, P. Eckl, E. Gottmann, F. Kassie, W. Rodinger, H. Steinkellner,
- C. Windpassinger, R. Schulte-Hermann, and S. Knasmüller.
- Genotoxic and ecotoxic effects of groundwaters and their relation to
- routinely measured chemical parameters.
- = succeed "," do
- %em Environ. Sci. Technol.
- 32:1799-1805, 1998.
- %dt
- [
- %a{:name => "knasmueller98"}> 41
- ]
- %dd
- S. Knasmüller, C. Helma, P. Eckl, E. Gottmann, H. Steinkellner, F. Kassie,
- T. Haider, W. Parzefall, and R. Schulte-Hermann.
- Investigations on genotoxic effects of groundwater from the
- Mitterndorfer Senke from the vicinity of Wiener Neustadt.
- = succeed "," do
- %em Wiener Klinische Wochenschrift
- 110:824-833, 1998.
- %dt
- [
- %a{:name => "kramer98"}> 42
- ]
- %dd
- S. Kramer, B. Pfahringer, and C. Helma.
- Stochastic propositionalization of non-determinate background
- knowledge.
- In
- = succeed "," do
- %em
- Proceedings of the 8th International Workshop on Inductive
- Logic Programming (ILP-98)
- pages 80-94, Berlin Heidelberg New York, 1998.
- Springer.
- %dt
- [
- %a{:name => "steinkellner98"}> 43
- ]
- %dd
- H. Steinkellner, M.S. Kong, C. Helma, S. Ecker, T.H. Ma, O. Horak, M. Kundi,
- and S. Knasmüller.
- Genotoxic effects of heavy metals: Comparative investigation with
- plant bioassays.
- = succeed "," do
- %em Environ. Mol. Mutagen.
- 31:183-191, 1998.
- %dt
- [
- %a{:name => "helma97a"}> 44
- ]
- %dd
- C. Helma and S. Knasmüller.
- Die Belastung von Gewässern mit gentoxischen Substanzen
- IIa: Die Quellen gentoxischer Kontaminationen (Industrielle
- Emissionen).
- = succeed "," do
- %em UWSF-Z.Umweltchem.Ökotox.
- 9:41-48, 1997.
- %dt
- [
- %a{:name => "helma97b"}> 45
- ]
- %dd
- C. Helma and S. Knasmüller.
- Die Belastung von Gewässern mit gentoxischen Substanzen
- IIb: Die Quellen gentoxischer Kontaminationen (Nichtindustrielle
- Emissionen).
- = succeed "," do
- %em UWSF-Z.Umweltchem.Ökotox.
- 9:163-168, 1997.
- %dt
- [
- %a{:name => "helma97c"}> 46
- ]
- %dd
- C. Helma.
- Die Situation der Chlorchemie in Östereich: Chlorhältige
- Pflanzenschutz- Holzschutz und Wasserdesinfektionsmittel - Entwicklungen im
- Zeitraum 1993 bis 1997.
- Technical report, Gesellschaft Österreichischer Chemiker, 1997.
- %dt
- [
- %a{:name => "knasmueller97"}> 47
- ]
- %dd
- S. Knasmüller, W. Parzefall, C. Helma, F. Kassie, S. Ecker, and
- R. Schulte-Hermann.
- Toxic effects of griseofulvin: Disease models, mechanisms, and risk
- assessment.
- = succeed "," do
- %em Critical Reviews in Toxicology
- 27:495-537, 1997.
- %dt
- [
- %a{:name => "kramer97a"}> 48
- ]
- %dd
- S. Kramer, B. Pfahringer, and C. Helma.
- Mining for causes of cancer: Machine learning experiments at various
- levels of detail.
- In
- = succeed "," do
- %em
- Proceedings of the Third International Conference on
- Knowledge Discovery and Data Mining (KDD-97)
- Menlo Park, CA, 1997. AAAI
- Press.
- %dt
- [
- %a{:name => "helma96a"}> 49
- ]
- %dd
- C. Helma, V. Mersch-Sundermann, V.S. Houk, U. Glasbrenner, C. Klein,
- L. Wenquing, K. Fekadu, R. Schulte-Hermann, and S. Knasmüller.
- Comparative evaluation of four bacterial assays for the detection of
- genotoxic effects in water samples.
- = succeed "," do
- %em Environ. Sci. Technol.
- 30:897-907, 1996.
- %dt
- [
- %a{:name => "helma95"}> 50
- ]
- %dd
- C. Helma, L. Kronberg, T.H. Ma, and S. Knasmüller.
- Genotoxic effects of the chlorinated hydroxyfuranones
- 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone and
- 3,4-dichloro-5-hydroxy-2[5H]-furanone in
- %i Tradescantia
- micronucleus assays.
- = succeed "," do
- %em Mutation Res.
- 346:181-186, 1995.
- %dt
- [
- %a{:name => "helma95b"}> 51
- ]
- %dd
- C. Helma.
- Erfahrungen mit dem Einsatz biologischer Mutationstests zur
- Verfahrensoptimierung und Umweltkontrolle.
- In
- = succeed "," do
- %em Handbuch der Umwelttechnik 1995
- pages 266-267. Wien, 1995.
- %dt
- [
- %a{:name => "helma95c"}> 52
- ]
- %dd
- C. Helma.
- Detection of genotoxic contaminations in water.
- In M. Guminska and J. Miedzobrodzki, editors,
- = succeed "," do
- %em
- Molecular Biology
- for Environment and Man
- pages 99-111. 1995.
- %dt
- [
- %a{:name => "helma94a"}> 53
- ]
- %dd
- C. Helma, R. Sommer, R. Schulte-Hermann, and S. Knasmüller.
- Enhanced clastogenicity of contaminated ground water following UV
- irradiation detected by the
- %em Tradescantia
- micronucleus assay.
- = succeed "," do
- %em Mutation Res.
- 323:93-98, 1994.
- %dt
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- C. Helma, S. Knasmüller, and R. Schulte-Hermann.
- Die Belastung von Wässern mit gentoxischen Substanzen I. Methoden
- zur Prüfung der Gentoxizität.
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- 6:277-288, 1994.
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- C. Helma, S. Knasmüller, and R. Schulte-Hermann.
- Biologische Tests zur Prüfung der Gentoxizität:
- Einsatzmöglichkeiten zur Verfahrensoptimierung und Emissionskontrolle.
- In Brandl et al., editor,
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- %em
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- pages 497-512. Wien, 1994.
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- E. Fassold, C. Helma, S. Knasmüller, and R. Sattelberger.
- Die Situation der Chlorchemie in Östereich, 8. Teil:
- Chlorhältige Pflanzenschutz- Holzschutz und Wasserdesinfektionsmittel.
- Technical report, Gesellschaft Österreichischer Chemiker, 1993.
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- C. Helma et.al.
- Abfallarme Großküche.
- Technical report, Österreichisches Ökologie Institut, 1992.
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