in silico toxicology gmbh
in silico toxicology is a research oriented company focussing on the development of
open source
predictive toxicology software and services. We are specialized in developing and applying advanced
data mining algorithms for complex chemical and biological data.
lazar
is our free webservice for toxicity predictions. Other developments had to be abandoned due to the lack of funding for maintenance and development.
Webservices
lazar
(Lazy Structure- Activity Relationships) makes toxicity predictions for chemical structures. It
uses an automated and reproducible read across algorithm and shows rationales for predictions, applicability domain estimations and validation results in a clear
graphical interface.
Batch predictions are available on request.
nano-lazar
is a proof-of-concept application for read-across predictions of nanoparticle toxicities. The application was developed for the
eNanoMapper project, and will not be maintained.
PubChem read across predicts potential gene/protein targets of chemical structures. This is a quick prototype, that will not be maintained.
Source code for our projects and publications.
Please head to Google scholar.
EU Projects
- eNanoMapper
- A Database and Ontology Framework for Nanomaterials Design and Safety Assessment
- ToxBank
- Supporting integrated data analysis and servicing of alternative testing methods in toxicology (WP leader)
- ModNanoTox
- Modelling toxicity behaviour of engineered nanoparticles (WP leader)
- OpenTox
- An open source predictive toxicology framework (scientific leader, WP leader)
- Sens-it-iv
- Novel testing strategies for in vitro assessment of allergens (WP leader)
- Scarlet
- Workshop on in silico methods for carcinogenicity and mutagenicity
Awards
- Research Price for Alternative Methods to Animal Experiments (German Federal Ministry on Consumer Protection, Food and Agriculture, 2005)
- Research Prize for Cancer Research without Animal Experiments (Doctors Against Animal Experiments, 2006)
Contact
in silico toxicology gmbh
Rastatterstrasse 41
CH-4057 Basel, Switzerland
Email:helma@in-silico.ch
Phone: +41-774339164
© in silico toxicology gmbh 2004-2020