Representational State Transfer or RESTful API is an architectural style to design webservices. 
REST uses HTTP protocol requests GET, POST, PUT, DELETE for the communication between distributed webservices.
`nano-lazar`\cite{helma_2017} as a part of the eNanoMapper analysis and modelling infrastructure is built upon the OpenTox 
web services framework following the principles of the Representational State Transfer (REST) design model.