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-{
- "uuid": "IUC5-6bdaad41-66c2-4d24-99ee-8d579243ddd9",
- "owner": {
- "substance": {
- "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
- },
- "company": {
- "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
- "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
- }
- },
- "citation": {
- "title": "Thurnherr, T. et al.",
- "year": "2011",
- "owner": ""
- },
- "protocol": {
- "topcategory": "TOX",
- "category": {
- "code": "TO_GENETIC_IN_VITRO_SECTION",
- "term": "http://www.bioassayontology.org/bao#BAO_0002167",
- "title": "7.6.1 Genetic toxicity in vitro"
- },
- "endpoint": "Exp Supporting Genetic toxicity in vitro.008",
- "guideline": [
- null
- ]
- },
- "parameters": {
- "Metabolic activation system": null,
- "Species": "human pulmonary epithelial cell line A549",
- "Target gene": null,
- "Type of genotoxicity": "chromosome and DNA damage",
- "Type of study": "Micronucleus test in vitro (MNvit) and Comet assay in vitro"
- },
- "reliability": {
- "r_isRobustStudy": "false",
- "r_isUsedforClassification": "false",
- "r_isUsedforMSDS": "false",
- "r_purposeFlag": "supporting study",
- "r_studyResultType": "experimental result",
- "r_value": "other:"
- },
- "interpretation": {
- "result": null
- },
- "effects": [
- {
- "endpoint": "GENOTOXICITY",
- "conditions": {
- "Metabolic activation": "without",
- "Species": "A549"
- },
- "result": {
- "unit": null,
- "textValue": "negative"
- }
- },
- {
- "endpoint": "GENOTOXICITY",
- "conditions": {
- "Metabolic activation": "without",
- "Species": "A549"
- },
- "result": {
- "unit": null,
- "textValue": "negative"
- }
- }
- ]
-}