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+{
+ "uuid": "IUC5-6bdaad41-66c2-4d24-99ee-8d579243ddd9",
+ "owner": {
+ "substance": {
+ "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
+ },
+ "company": {
+ "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
+ "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
+ }
+ },
+ "citation": {
+ "title": "Thurnherr, T. et al.",
+ "year": "2011",
+ "owner": ""
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "TO_GENETIC_IN_VITRO_SECTION",
+ "term": "http://www.bioassayontology.org/bao#BAO_0002167",
+ "title": "7.6.1 Genetic toxicity in vitro"
+ },
+ "endpoint": "Exp Supporting Genetic toxicity in vitro.008",
+ "guideline": [
+ null
+ ]
+ },
+ "parameters": {
+ "Metabolic activation system": null,
+ "Species": "human pulmonary epithelial cell line A549",
+ "Target gene": null,
+ "Type of genotoxicity": "chromosome and DNA damage",
+ "Type of study": "Micronucleus test in vitro (MNvit) and Comet assay in vitro"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": "supporting study",
+ "r_studyResultType": "experimental result",
+ "r_value": "other:"
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "GENOTOXICITY",
+ "conditions": {
+ "Metabolic activation": "without",
+ "Species": "A549"
+ },
+ "result": {
+ "unit": null,
+ "textValue": "negative"
+ }
+ },
+ {
+ "endpoint": "GENOTOXICITY",
+ "conditions": {
+ "Metabolic activation": "without",
+ "Species": "A549"
+ },
+ "result": {
+ "unit": null,
+ "textValue": "negative"
+ }
+ }
+ ]
+}