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diff --git a/test/data/enm/study-XLSX-0768a016-0b68-4992-a896-ce2a9dadca36.json b/test/data/enm/study-XLSX-0768a016-0b68-4992-a896-ce2a9dadca36.json
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--- a/test/data/enm/study-XLSX-0768a016-0b68-4992-a896-ce2a9dadca36.json
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@@ -1,1016 +0,0 @@
-{
- "uuid": "XLSX-0768a016-0b68-4992-a896-ce2a9dadca36",
- "owner": {
- "substance": {
- "uuid": "XLSX-b4e4a8e9-6d27-3218-a243-7aa30560adb1"
- },
- "company": {
- "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
- "name": "FP7 MARINA"
- }
- },
- "citation": {
- "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
- "year": "2015",
- "owner": "P32 - KI"
- },
- "protocol": {
- "topcategory": "TOX",
- "category": {
- "code": "NPO_1709_SECTION",
- "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
- "title": "NPO_1709 LDH Release Assay"
- },
- "endpoint": "Cell viability - cell membrane damage: Lactate dehydrogenase assay (LDH) (CytoTox 96® Non-radioactive cytotoxicity assay - Promega, G1780) ",
- "guideline": [
- "Cytotoxicity using human monocyte-derived macrophages (HMDM)"
- ]
- },
- "parameters": {
- "CHMO:0002774": "N",
- "CLO_0000031": "HMDM",
- "CLO_0000031 EFO_0004443": "Karolinska University Hospital, Stockholm, Sweden - buffy coats from healthy adult blood donors ",
- "Cell culture conditions - Serum": "FBS (Gibco, 10500) ",
- "Cell culture conditions - Serum concentration in growth medium": 0.1,
- "Cell culture conditions - Serum concentration in treatment medium": "0,05%",
- "Cell line/Type - Full name": "Primary human monocyte-derived macrophages (HMDM)",
- "Dispersion agent": "water with 0,05% BSA",
- "NPO_1952": "Y",
- "NPO_1961": "Y",
- "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
- "OBI_0001911 BAO_0000114": "RPMI (Sigma, R0833)"
- },
- "reliability": {
- "r_isRobustStudy": "false",
- "r_isUsedforClassification": "false",
- "r_isUsedforMSDS": "false",
- "r_purposeFlag": null,
- "r_studyResultType": "experimental result",
- "r_value": null
- },
- "interpretation": {
- "result": null
- },
- "effects": [
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 0,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 1,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 96.376
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 5,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 95.98
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 10,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 96.507
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 25,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 94.882
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 50,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 97.985
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 75,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 96.109
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 100,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 77.37
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 0,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 1,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 103.739
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 5,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 102.574
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 10,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 102.473
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 25,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 102.827
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 50,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 102.473
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 75,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100.108
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 100,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 91.666
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 0,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 1,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100.371
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 5,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 102.324
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 10,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100.424
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 25,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 96.868
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 50,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 79.298
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 75,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 83.237
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 100,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 6,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 78.43
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 0,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 1,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 93.007
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 5,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 86.814
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 10,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 73.76
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 25,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 67.005
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 50,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 68.435
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 75,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 66.78
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 100,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 1",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 52.622
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 0,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 1,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100.652
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 5,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 97.48
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 10,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 85.023
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 25,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 74.673
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 50,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 71.709
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 75,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 72.678
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 100,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 2",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 61.105
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 0,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 100
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 1,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 118.083
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 5,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 121.026
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 10,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 139.29
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 25,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 53.388
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 50,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 53.162
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 75,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 75.72
- }
- },
- {
- "endpoint": "% cell viability",
- "conditions": {
- "Concentration": {
- "loQualifier": "=",
- "loValue": 100,
- "unit": "µg/ml"
- },
- "Replicate": "Replicate 3",
- "Time point": {
- "loQualifier": "=",
- "loValue": 24,
- "unit": "h"
- }
- },
- "result": {
- "unit": "%",
- "loValue": 43.694
- }
- }
- ]
-}
generated by cgit v1.2.3 (git 2.25.1) at 2024-04-30 16:40:01 +0000