{
  "uuid": "IUC5-6bdaad41-66c2-4d24-99ee-8d579243ddd9",
  "owner": {
    "substance": {
      "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
    },
    "company": {
      "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
      "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
    }
  },
  "citation": {
    "title": "Thurnherr, T. et al.",
    "year": "2011",
    "owner": ""
  },
  "protocol": {
    "topcategory": "TOX",
    "category": {
      "code": "TO_GENETIC_IN_VITRO_SECTION",
      "term": "http://www.bioassayontology.org/bao#BAO_0002167",
      "title": "7.6.1 Genetic toxicity in vitro"
    },
    "endpoint": "Exp Supporting Genetic toxicity in vitro.008",
    "guideline": [
      null
    ]
  },
  "parameters": {
    "Metabolic activation system": null,
    "Species": "human pulmonary epithelial cell line A549",
    "Target gene": null,
    "Type of genotoxicity": "chromosome and DNA damage",
    "Type of study": "Micronucleus test in vitro (MNvit) and Comet assay in vitro"
  },
  "reliability": {
    "r_isRobustStudy": "false",
    "r_isUsedforClassification": "false",
    "r_isUsedforMSDS": "false",
    "r_purposeFlag": "supporting study",
    "r_studyResultType": "experimental result",
    "r_value": "other:"
  },
  "interpretation": {
    "result": null
  },
  "effects": [
    {
      "endpoint": "GENOTOXICITY",
      "conditions": {
        "Metabolic activation": "without",
        "Species": "A549"
      },
      "result": {
        "unit": null,
        "textValue": "negative"
      }
    },
    {
      "endpoint": "GENOTOXICITY",
      "conditions": {
        "Metabolic activation": "without",
        "Species": "A549"
      },
      "result": {
        "unit": null,
        "textValue": "negative"
      }
    }
  ]
}