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{
"uuid": "IUC5-49179f2f-867c-4e7c-8fd1-d09eb23c4c3d",
"owner": {
"substance": {
"uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
},
"company": {
"uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
"name": "Ideaconsult Ltd. / Sofia / Bulgaria"
}
},
"citation": {
"title": null,
"year": "2006",
"owner": ""
},
"protocol": {
"topcategory": "TOX",
"category": {
"code": "TO_ACUTE_ORAL_SECTION",
"term": "http://purl.enanomapper.org/onto/ENM_0000020",
"title": "7.2.1 Acute toxicity - oral"
},
"endpoint": "Acute toxicity: oral.001",
"guideline": [
"OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)"
]
},
"parameters": {
"Sex": "female",
"Species": "rat"
},
"reliability": {
"r_isRobustStudy": "false",
"r_isUsedforClassification": "false",
"r_isUsedforMSDS": "false",
"r_purposeFlag": "key study",
"r_studyResultType": "experimental result",
"r_value": "1 (reliable without restriction)"
},
"interpretation": {
"result": "practically nontoxic"
},
"effects": [
{
"endpoint": "LDLo",
"conditions": {
"Sex": "female"
},
"result": {
"unit": "mg/kg bw",
"loQualifier": ">=",
"loValue": 2000
}
},
{
"endpoint": "LD50 cut-off ",
"conditions": {
"Sex": "female"
},
"result": {
"unit": "mg/kg bw",
"loQualifier": ">=",
"loValue": 5000
}
}
]
}
|
