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{
"uuid": "IUC5-6bdaad41-66c2-4d24-99ee-8d579243ddd9",
"owner": {
"substance": {
"uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
},
"company": {
"uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
"name": "Ideaconsult Ltd. / Sofia / Bulgaria"
}
},
"citation": {
"title": "Thurnherr, T. et al.",
"year": "2011",
"owner": ""
},
"protocol": {
"topcategory": "TOX",
"category": {
"code": "TO_GENETIC_IN_VITRO_SECTION",
"term": "http://www.bioassayontology.org/bao#BAO_0002167",
"title": "7.6.1 Genetic toxicity in vitro"
},
"endpoint": "Exp Supporting Genetic toxicity in vitro.008",
"guideline": [
null
]
},
"parameters": {
"Metabolic activation system": null,
"Species": "human pulmonary epithelial cell line A549",
"Target gene": null,
"Type of genotoxicity": "chromosome and DNA damage",
"Type of study": "Micronucleus test in vitro (MNvit) and Comet assay in vitro"
},
"reliability": {
"r_isRobustStudy": "false",
"r_isUsedforClassification": "false",
"r_isUsedforMSDS": "false",
"r_purposeFlag": "supporting study",
"r_studyResultType": "experimental result",
"r_value": "other:"
},
"interpretation": {
"result": null
},
"effects": [
{
"endpoint": "GENOTOXICITY",
"conditions": {
"Metabolic activation": "without",
"Species": "A549"
},
"result": {
"unit": null,
"textValue": "negative"
}
},
{
"endpoint": "GENOTOXICITY",
"conditions": {
"Metabolic activation": "without",
"Species": "A549"
},
"result": {
"unit": null,
"textValue": "negative"
}
}
]
}
|
