diff options
Diffstat (limited to 'data/GENOTOX_data_and_dictionary.csv')
| -rw-r--r-- | data/GENOTOX_data_and_dictionary.csv | 1084 |
1 files changed, 542 insertions, 542 deletions
diff --git a/data/GENOTOX_data_and_dictionary.csv b/data/GENOTOX_data_and_dictionary.csv index 067e05a..ef17b51 100644 --- a/data/GENOTOX_data_and_dictionary.csv +++ b/data/GENOTOX_data_and_dictionary.csv @@ -124,21 +124,21 @@ "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Wistar","6","Male","oral: gavage","12","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Wistar","6","Male","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","mammalian germ cell cytogenetic assay","in vivo","Equivalent or similar to","OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)","Yes","Acceptable","House mouse (as animal)","NMRI","7","Male","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5?S,6S,6?R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6?-[(2S)-butan-2-yl]-20,20b-dihydroxy-5?,6,8,19-tetramethyl-17-oxo-5?,6,6?,10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2?-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","chromosome aberration assay","in vivo","Equivalent or similar to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","Yes","Acceptable","House mouse (as animal)","CD-1","","Male","Not reported","24","h","yes","not applicable","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is part of a mixture or forumlation","Avermectin B1a","265-610-3","65195-55-3","(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Abamectin (Avermectin B1a)","C48H72O14","CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C","InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1","organic","compound","PubChem isomeric SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","chromosome aberration assay","in vivo","Equivalent or similar to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","Yes","Acceptable","House mouse (as animal)","CD-1","","Male","Not reported","24","h","yes","not applicable","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: The Netherlands","Acequinocyl (Revised addendum)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" @@ -348,22 +348,22 @@ "Amisulbrom","","348635-87-0","single chemical entity","Component is identical to the substance","Amisulbrom","","348635-87-0","3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide","Amisulbrom","C13H13BrFN5O4S2","CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br","InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","single cell gel/comet assay in mammalian cells for detection of DNA damage","in vivo","Equivalent or similar to","OECD Guideline 489","Yes","Acceptable","Rat (as animal)","Wistar","4","Female","oral: gavage","24","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Amisulbrom","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom","41736","2014","doi:10.2903/j.efsa.2014.3237" "Amisulbrom","","348635-87-0","single chemical entity","Component is identical to the substance","Amisulbrom","","348635-87-0","3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide","Amisulbrom","C13H13BrFN5O4S2","CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br","InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","6","Male","intraperitoneal","24","h","yes","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Amisulbrom","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom","41736","2014","doi:10.2903/j.efsa.2014.3237" "Amisulbrom","","348635-87-0","single chemical entity","Component is identical to the substance","Amisulbrom","","348635-87-0","3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide","Amisulbrom","C13H13BrFN5O4S2","CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br","InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","Yes","Acceptable","House mouse (as animal)","CD-1","6","Male","oral: gavage","24","h","yes","not applicable","Negative","","no evidence","RMS: The United Kingdom","Amisulbrom","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom","41736","2014","doi:10.2903/j.efsa.2014.3237" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" "Azimsulfuron","601-676-5","120162-55-2","single chemical entity","Component is identical to the substance","Azimsulfuron","601-676-5","120162-55-2","N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","Azimsulfuron","C13H16N10O5S","Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3","InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)","organic","compound","Other","Other","DNA damage and/or repair","DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro","in vitro","According to","OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)","No","Acceptable","Rat (as animal)","hepatocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Sweden - CoRMS: Slovenia","Azimsulfuron (Corrigendum)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron","40263","2010","doi:10.2903/j.efsa.2010.1554" "Azimsulfuron","601-676-5","120162-55-2","single chemical entity","Component is a metabolite of the substance","N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","","","N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","Not in list","C12H14N10O5S","Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3","InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Sweden - CoRMS: Slovenia","Azimsulfuron (Corrigendum)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron","40263","2010","doi:10.2903/j.efsa.2010.1554" "Azimsulfuron","601-676-5","120162-55-2","single chemical entity","Component is a metabolite of the substance","N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","","","N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide","Not in list","C12H14N10O5S","Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3","InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Sweden - CoRMS: Slovenia","Azimsulfuron (Corrigendum)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron","40263","2010","doi:10.2903/j.efsa.2010.1554" @@ -586,21 +586,21 @@ "Bitertanol","259-513-5","55179-31-2","single chemical entity","Component is identical to the substance","Bitertanol","259-513-5","55179-31-2","1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol","Bitertanol","C20H23N3O2","CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3","InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3","organic","compound","Other","Other","chromosome aberration","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Sordaria brevicollis (as organism)","Not reported","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Bitertanol","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol","40476","2010","doi:10.2903/j.efsa.2010.1850" "Bitertanol","259-513-5","55179-31-2","single chemical entity","Component is identical to the substance","Bitertanol","259-513-5","55179-31-2","1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol","Bitertanol","C20H23N3O2","CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3","InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","Yes","Acceptable","House mouse (as animal)","NMRI","","Male/Female","oral: gavage","6","h","no data","not applicable","Negative","","no evidence","RMS: The United Kingdom","Bitertanol","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol","40476","2010","doi:10.2903/j.efsa.2010.1850" "Bitertanol","259-513-5","55179-31-2","single chemical entity","Component is identical to the substance","Bitertanol","259-513-5","55179-31-2","1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol","Bitertanol","C20H23N3O2","CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3","InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3","organic","compound","Other","Other","chromosome aberration","dominant lethal assay","in vivo","According to","OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)","No","Acceptable","House mouse (as animal)","NMRI","50","Male","oral: unspecified","","","yes","not applicable","Negative","","","RMS: The United Kingdom","Bitertanol","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol","40476","2010","doi:10.2903/j.efsa.2010.1850" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" -"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3?,4?-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" +"Bixafen","","581809-46-3","single chemical entity","Component is identical to the substance","Bixafen","","581809-46-3","N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Bixafen","C18H12Cl2F3N3O","FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1","InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Bixafen","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen","41218","2012","doi:10.2903/j.efsa.2012.2917" "Bromadiolone","249-205-9","28772-56-7","single chemical entity","Component is identical to the substance","Bromadiolone","249-205-9","28772-56-7","3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O","InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Sweden","Bromadiolone","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone","40464","2010","doi:10.2903/j.efsa.2010.1783" "Bromadiolone","249-205-9","28772-56-7","single chemical entity","Component is identical to the substance","Bromadiolone","249-205-9","28772-56-7","3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- @@ -911,32 +911,32 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","sister chromatid exchange assay in mammalian cells","in vivo","No guideline available","Not reported","Not applicable","Acceptable","House mouse (as animal)","B6C3F1","4","Male","intraperitoneal","23","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" "8-Hydroxyquinoline","205-711-1","148-24-3","single chemical entity","Component is identical to the substance","8-Hydroxyquinoline","205-711-1","148-24-3","Quinolin-8-ol","Not in list","C9H7NO","C1=CC2=C(C(=C1)O)N=CC=C2","InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","sister chromatid exchange assay in mammalian cells","in vivo","No guideline available","Not reported","Not applicable","Acceptable","House mouse (as animal)","B6C3F1","4","Male","intraperitoneal","42","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Spain","8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline","40571","2011","doi:10.2903/j.efsa.2011.1964" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6?-(butan-2-yl)-19,21b-dihydroxy-5?,10,12,20-tetramethyl-1-oxo-3,4,5?,6?,8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2?-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" -"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5?S,6R,6?R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6?-[(2S)-butan-2-yl]-19,19b-dihydroxy-5?,6,7,18-tetramethyl-16-oxo-5?,6,6?,9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2?-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","mixture or formulation","Component is identical to the substance","Abamectin","","71751-41-2","(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside","Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)","C49H74O14","CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C","InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-","organic","representative compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" +"Abamectin","","71751-41-2","single chemical entity","Component is a metabolite of the substance","[8,9-Z]-isomer of avermectin B1a","","","{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside","Avermectin B1a, delta-8,9 isomer","C47H70O14","CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O","InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Abamectin","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi","39658","2008","doi:10.2903/j.efsa.2008.147r" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" "Acequinocyl","","57960-19-7","single chemical entity","Component is identical to the substance","Acequinocyl","","57960-19-7","3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate","Acequinocyl","C24H32O4","CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O","InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Acequinocyl (Revised version of September 2007)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.","41396","2013","doi:10.2903/j.efsa.2013.3212" @@ -1497,41 +1497,41 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "L-ascorbic acid","200-066-2","50-81-7","single chemical entity","Component is identical to the substance","L-ascorbic acid","200-066-2","50-81-7","(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one","L-ascorbic acid","C6H8O6","C(C(C1C(=C(C(=O)O1)O)O)O)O","InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","sister chromatid exchange assay in mammalian cells","in vivo","No guideline available","Not reported","Not applicable","Acceptable","Hamster (as animal)","Not reported","","No data","Not reported","","","no data","not applicable","Negative","","","RMS: The Netherlands","L-ascorbic acid","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid","41389","2013","doi: 10.2903/j.efsa.2013.3197" "L-ascorbic acid","200-066-2","50-81-7","single chemical entity","Component is identical to the substance","L-ascorbic acid","200-066-2","50-81-7","(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one","L-ascorbic acid","C6H8O6","C(C(C1C(=C(C(=O)O1)O)O)O)O","InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No data","Acceptable","House mouse (as animal)","CD-1","","No data","Not reported","","","no data","not applicable","Negative","","","RMS: The Netherlands","L-ascorbic acid","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid","41389","2013","doi: 10.2903/j.efsa.2013.3197" "L-ascorbic acid","200-066-2","50-81-7","single chemical entity","Component is identical to the substance","L-ascorbic acid","200-066-2","50-81-7","(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one","L-ascorbic acid","C6H8O6","C(C(C1C(=C(C(=O)O1)O)O)O)O","InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No data","Acceptable","House mouse (as animal)","B6C3F1","","No data","Not reported","","","no data","not applicable","Negative","","","RMS: The Netherlands","L-ascorbic acid","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid","41389","2013","doi: 10.2903/j.efsa.2013.3197" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","72","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" -"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b?c?]difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Trifolio-M GmbH source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: microorganisms or derived from microorganisms","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Sipcam S.p.A source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Azadirachtin","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","72","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" +"Azadirachtin A","","11141-17-6","complex product: derived from botanical sources","Component is the active ingredient of the mixture or formulation","Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)","","","methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate","Not in list","C35H44O16","C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C","InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Azadirachtin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin","40619","2011","doi:10.2903/j.efsa.2011.1858" "Benfluralin","217-465-2","1861-40-1","single chemical entity","Component is identical to the substance","Benfluralin","217-465-2","1861-40-1","N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline","Benfluralin","C13H16F3N3O4","CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]","InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Belgium","Benfluralin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin","39657","2008","doi:10.2903/j.efsa.2008.127r" "Benfluralin","217-465-2","1861-40-1","single chemical entity","Component is identical to the substance","Benfluralin","217-465-2","1861-40-1","N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline","Benfluralin","C13H16F3N3O4","CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]","InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Belgium","Benfluralin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin","39657","2008","doi:10.2903/j.efsa.2008.127r" "Benfluralin","217-465-2","1861-40-1","single chemical entity","Component is identical to the substance","Benfluralin","217-465-2","1861-40-1","N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline","Benfluralin","C13H16F3N3O4","CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]","InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Belgium","Benfluralin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin","39657","2008","doi:10.2903/j.efsa.2008.127r" @@ -2333,20 +2333,20 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","2-chlorobenzenesulfonamide","230-156-7","6961-82-6","2-chlorobenzenesulfonamide","Not in list","C6H6ClNO2S","C1=CC=C(C(=C1)S(=O)(=O)N)Cl","InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" "Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","2-chlorobenzenesulfonamide","230-156-7","6961-82-6","2-chlorobenzenesulfonamide","Not in list","C6H6ClNO2S","C1=CC=C(C(=C1)S(=O)(=O)N)Cl","InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" "Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","2-chlorobenzenesulfonamide","230-156-7","6961-82-6","2-chlorobenzenesulfonamide","Not in list","C6H6ClNO2S","C1=CC=C(C(=C1)S(=O)(=O)N)Cl","InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" -"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N?-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" +"Chlorsulfuron","265-268-5","64902-72-3","single chemical entity","Component is a metabolite of the substance","N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide","","","N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid","Not in list","C9H10ClN5O4S","O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl","InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Chlorsulfuron","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron","39878","2009","doi:10.2903/j.efsa.2009.201r" "Clopyralid","216-935-4","1702-17-6","single chemical entity","Component is identical to the substance","Clopyralid","216-935-4","1702-17-6","3,6-dichloropyridine-2-carboxylic acid","Clopyralid","C6H3Cl2NO2","C1=CC(=NC(=C1Cl)C(=O)O)Cl","InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Clopyralid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid","38740","2006","doi: 10.2903/j.efsa.2006.50r" "Clopyralid","216-935-4","1702-17-6","single chemical entity","Component is identical to the substance","Clopyralid","216-935-4","1702-17-6","3,6-dichloropyridine-2-carboxylic acid","Clopyralid","C6H3Cl2NO2","C1=CC(=NC(=C1Cl)C(=O)O)Cl","InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Clopyralid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid","38740","2006","doi: 10.2903/j.efsa.2006.50r" "Clopyralid","216-935-4","1702-17-6","single chemical entity","Component is identical to the substance","Clopyralid","216-935-4","1702-17-6","3,6-dichloropyridine-2-carboxylic acid","Clopyralid","C6H3Cl2NO2","C1=CC(=NC(=C1Cl)C(=O)O)Cl","InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Clopyralid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid","38740","2006","doi: 10.2903/j.efsa.2006.50r" @@ -2674,28 +2674,28 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Cymoxanil","261-043-0","57966-95-7","single chemical entity","Component is identical to the substance","Cymoxanil","261-043-0","57966-95-7","(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide","Cymoxanil","C7H10N4O3","CCNC(=O)NC(=O)/C(=N/OC)/C#N","InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+","organic","representative isomer","PubChem isomeric SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Crj:CD(SD)","5","Male","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Austria","Cymoxanil","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil","39738","2008","doi:10.2903/j.efsa.2008.167r" "Cymoxanil","261-043-0","57966-95-7","single chemical entity","Component is identical to the substance","Cymoxanil","261-043-0","57966-95-7","(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide","Cymoxanil","C7H10N4O3","CCNC(=O)NC(=O)/C(=N/OC)/C#N","InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+","organic","representative isomer","PubChem isomeric SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Crj:CD(SD)","5","Male","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Austria","Cymoxanil","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil","39738","2008","doi:10.2903/j.efsa.2008.167r" "Cymoxanil","261-043-0","57966-95-7","single chemical entity","Component is identical to the substance","Cymoxanil","261-043-0","57966-95-7","(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide","Cymoxanil","C7H10N4O3","CCNC(=O)NC(=O)/C(=N/OC)/C#N","InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+","organic","representative isomer","PubChem isomeric SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","Equivalent or similar to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","Yes","Acceptable","Rat (as animal)","Crj:CD(SD)","5","Male","oral: gavage","2","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Austria","Cymoxanil","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil","39738","2008","doi:10.2903/j.efsa.2008.167r" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","no information","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","without","Ambiguous","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","with","Ambiguous","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","","Male","oral: unspecified","4","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","","Male","oral: unspecified","12","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","dominant lethal assay","in vivo","Equivalent or similar to","OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)","Yes","Acceptable","House mouse (as animal)","CD-1","105","Male","oral: gavage","5","D","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","no information","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","without","Ambiguous","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","with","Ambiguous","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","C57BL","10","Male/Female","oral: unspecified","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","","Male","oral: unspecified","4","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","","Male","oral: unspecified","12","h","yes","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","dominant lethal assay","in vivo","Equivalent or similar to","OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)","Yes","Acceptable","House mouse (as animal)","CD-1","105","Male","oral: gavage","5","D","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" "Diquat","220-433-0","85-00-7","single chemical entity","Component is a metabolite of the substance","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","","","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","Not in list","C8H9N2O","O=C1NCC[n+]2ccccc12","InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" "Diquat","220-433-0","85-00-7","single chemical entity","Component is a metabolite of the substance","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","","","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","Not in list","C8H9N2O","O=C1NCC[n+]2ccccc12","InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" "Diquat","220-433-0","85-00-7","single chemical entity","Component is a metabolite of the substance","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","","","1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium","Not in list","C8H9N2O","O=C1NCC[n+]2ccccc12","InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1","organic","compound","Other","Other","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" @@ -2924,18 +2924,18 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Cyflufenamid","","180409-60-3","single chemical entity","Component is identical to the substance","Cyflufenamid","","180409-60-3","N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide","Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer","C20H17F5N2O2","C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F","InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is identical to the substance","Cyflufenamid","","180409-60-3","N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide","Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer","C20H17F5N2O2","C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F","InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","4","Male","oral: gavage","2","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is identical to the substance","Cyflufenamid","","180409-60-3","N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide","Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer","C20H17F5N2O2","C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F","InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","4","Male","oral: gavage","14","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" -"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N?-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" +"Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C12H11F5N2O","N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F","InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C8H5F5N2","Fc1c(C(=N)N)c(ccc1F)C(F)(F)F","InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C8H5F5N2","Fc1c(C(=N)N)c(ccc1F)C(F)(F)F","InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","CM891","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" "Cyflufenamid","","180409-60-3","single chemical entity","Component is a metabolite of the substance","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","","","2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide","Not in list","C8H5F5N2","Fc1c(C(=N)N)c(ccc1F)C(F)(F)F","InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Cyflufenamid","2006","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance cyflufenamid","39962","2009","doi:10.2903/j.efsa.2009.258r" @@ -3330,28 +3330,28 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is identical to the substance","Etofenprox","407-980-2","80844-07-1","1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene","Etofenprox","C25H28O3","CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" "Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is identical to the substance","Etofenprox","407-980-2","80844-07-1","1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene","Etofenprox","C25H28O3","CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" "Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is identical to the substance","Etofenprox","407-980-2","80844-07-1","1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene","Etofenprox","C25H28O3","CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","CM871","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","CM871","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP67","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP67","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" -"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C(c)(c)COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","CM871","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","CM871","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP67","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP67","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","without","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" +"Etofenprox","407-980-2","80844-07-1","single chemical entity","Component is a metabolite of the substance","2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate","","117252-00-3","[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate","Not in list","C25H26O4","CCOC1=CC=C(C=C1)C¿¿COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3","InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","with","Negative","","","RMS: Italy","Etofenprox","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox","39904","2009","doi:10.2903/j.efsa.2009.213r" "Dimoxystrobin","","149961-52-4","single chemical entity","Component is identical to the substance","Dimoxystrobin","","149961-52-4","(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide","Dimoxystrobin","C19H22N2O3","CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC","InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Dimoxystrobin","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin","38595","2005","doi:10.2903/j.efsa.2005.46r" "Dimoxystrobin","","149961-52-4","single chemical entity","Component is identical to the substance","Dimoxystrobin","","149961-52-4","(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide","Dimoxystrobin","C19H22N2O3","CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC","InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Dimoxystrobin","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin","38595","2005","doi:10.2903/j.efsa.2005.46r" "Dimoxystrobin","","149961-52-4","single chemical entity","Component is identical to the substance","Dimoxystrobin","","149961-52-4","(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide","Dimoxystrobin","C19H22N2O3","CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC","InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-","organic","compound","PubChem isomeric SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Dimoxystrobin","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin","38595","2005","doi:10.2903/j.efsa.2005.46r" @@ -3799,7 +3799,7 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Bispyribac-sodium","","125401-92-5","single chemical entity","Component is a metabolite of the substance","benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt","","","sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate","Not in list","C18H15N4NaO8","[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O","InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","no data","with","Negative","","","RMS: Italy","Bispyribac-Sodium","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)","40476","2010","doi:10.2903/j.efsa.2010.1692" "Bispyribac-sodium","","125401-92-5","single chemical entity","Component is a metabolite of the substance","benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt","","","sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate","Not in list","C18H15N4NaO8","[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O","InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","no data","with","Negative","","","RMS: Italy","Bispyribac-Sodium","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)","40476","2010","doi:10.2903/j.efsa.2010.1692" "Bispyribac-sodium","","125401-92-5","single chemical entity","Component is a metabolite of the substance","benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt","","","sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate","Not in list","C18H15N4NaO8","[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O","InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","no data","with","Negative","","","RMS: Italy","Bispyribac-Sodium","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)","40476","2010","doi:10.2903/j.efsa.2010.1692" -"Benthiavalicarb-isopropyl","","177406-68-7","single chemical entity","Component is a metabolite of the substance","6,6'-difluoro-2,2'-dibenzothiazole","","","6,6?-difluoro-2,2?-bibenzo[d]thiazole","Not in list","C14H6F2N2S2","Fc1ccc2nc(sc2c1)c3nc4ccc(F)cc4s3","InChI=1S/C14H6F2N2S2/c15-7-1-3-9-11(5-7)19-13(17-9)14-18-10-4-2-8(16)6-12(10)20-14/h1-6H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Positive","","","RMS: Belgium","Benthiavalicarb-isopropyl","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb","39295","2007","doi:10.2903/j.efsa.2007.107r" +"Benthiavalicarb-isopropyl","","177406-68-7","single chemical entity","Component is a metabolite of the substance","6,6'-difluoro-2,2'-dibenzothiazole","","","6,6'-difluoro-2,2'-bibenzo[d]thiazole","Not in list","C14H6F2N2S2","Fc1ccc2nc(sc2c1)c3nc4ccc(F)cc4s3","InChI=1S/C14H6F2N2S2/c15-7-1-3-9-11(5-7)19-13(17-9)14-18-10-4-2-8(16)6-12(10)20-14/h1-6H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Positive","","","RMS: Belgium","Benthiavalicarb-isopropyl","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb","39295","2007","doi:10.2903/j.efsa.2007.107r" "Clethodim","","99129-21-2","single chemical entity","Component is identical to the substance","Clethodim","","99129-21-2","2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one","Clethodim","C17H26ClNO3S","CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O","InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Clethodim","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim","40837","2011","doi:10.2903/j.efsa.2011.2417" "Clethodim","","99129-21-2","single chemical entity","Component is identical to the substance","Clethodim","","99129-21-2","2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one","Clethodim","C17H26ClNO3S","CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O","InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands","Clethodim","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim","40837","2011","doi:10.2903/j.efsa.2011.2417" "Clethodim","","99129-21-2","single chemical entity","Component is identical to the substance","Clethodim","","99129-21-2","2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one","Clethodim","C17H26ClNO3S","CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O","InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands","Clethodim","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim","40837","2011","doi:10.2903/j.efsa.2011.2417" @@ -4210,48 +4210,48 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Benalaxyl-M","","98243-83-5","single chemical entity","Component is identical to the substance","Benalaxyl-M","","98243-83-5","methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate","Benalaxyl-M","C20H23NO3","C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC","InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","intraperitoneal","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Portugal","Benalaxyl-M","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.","41368","2013","doi:10.2903/j.efsa.2013.3148" "Benalaxyl-M","","98243-83-5","single chemical entity","Component is part of a group assessment","Benalaxyl","275-728-7","71626-11-4","Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate","Benalaxyl","C20H23NO3","CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2","InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Not reported","10","Male/Female","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Portugal","Benalaxyl-M","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.","41368","2013","doi:10.2903/j.efsa.2013.3148" "Benalaxyl-M","","98243-83-5","single chemical entity","Component is part of a group assessment","Benalaxyl","275-728-7","71626-11-4","Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate","Benalaxyl","C20H23NO3","CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2","InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Not reported","10","Male/Female","intraperitoneal","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Portugal","Benalaxyl-M","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.","41368","2013","doi:10.2903/j.efsa.2013.3148" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" -"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4?-cyano-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" +"Cyantraniliprole","","736994-63-1","single chemical entity","Component is identical to the substance","Cyantraniliprole","","736994-63-1","3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Not in list","C19H14BrClN6O2","CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N","InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","20","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" "Cyantraniliprole","","736994-63-1","single chemical entity","Component is a metabolite of the substance","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","","","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","Not in list","C19H15BrClN5O4","O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC","InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" "Cyantraniliprole","","736994-63-1","single chemical entity","Component is a metabolite of the substance","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","","","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","Not in list","C19H15BrClN5O4","O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC","InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" "Cyantraniliprole","","736994-63-1","single chemical entity","Component is a metabolite of the substance","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","","","4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid","Not in list","C19H15BrClN5O4","O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC","InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom - CoRMS: France","Cyantraniliprole (Final Addendum)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole","41891","2014","doi:10.2903/j.efsa.2014.3814" @@ -4408,34 +4408,34 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Eugenol","202-589-1","97-53-0","single chemical entity","Component is identical to the substance","Eugenol","202-589-1","97-53-0","2-Methoxy-4-prop-2-enylphenol","Not in list","C10H12O2","COC1=C(C=CC(=C1)CC=C)O","InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No data","Acceptable","Human (as organism)","","","No data","oral: capsule","8","D","no data","not applicable","Negative","","","RMS: The United Kingdom","Eugenol (Final Addendum)","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol","41218","2012","doi:10.2903/j.efsa.2012.2914" "Eugenol","202-589-1","97-53-0","single chemical entity","Component is identical to the substance","Eugenol","202-589-1","97-53-0","2-Methoxy-4-prop-2-enylphenol","Not in list","C10H12O2","COC1=C(C=CC(=C1)CC=C)O","InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","chromosome aberration assay","in vivo","Equivalent or similar to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No data","Acceptable","Human (as organism)","","","No data","oral: capsule","8","D","no data","not applicable","Negative","","","RMS: The United Kingdom","Eugenol (Final Addendum)","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol","41218","2012","doi:10.2903/j.efsa.2012.2914" "Eugenol","202-589-1","97-53-0","single chemical entity","Component is identical to the substance","Eugenol","202-589-1","97-53-0","2-Methoxy-4-prop-2-enylphenol","Not in list","C10H12O2","COC1=C(C=CC(=C1)CC=C)O","InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vivo","No guideline available","Not reported","Not applicable","Acceptable","House mouse (as animal)","Not reported","","No data","intraperitoneal","","","no data","not applicable","Negative","","","RMS: The United Kingdom","Eugenol (Final Addendum)","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol","41218","2012","doi:10.2903/j.efsa.2012.2914" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" -"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4?-chloro-1-(3 chloro-2-pyridyl)-2?-methyl-6?-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" +"Chlorantraniliprole","","500008-45-7","single chemical entity","Component is identical to the substance","Chlorantraniliprole","","500008-45-7","3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide","Chlorantraniliprole (DPX E-2Y45)","C18H14BrCl2N5O2","CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br","InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","CD-1","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" "Chlorantraniliprole","","500008-45-7","single chemical entity","Component is a metabolite of the substance","2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","","","2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","Not in list","C18H12BrCl2N5O","Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O","InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" "Chlorantraniliprole","","500008-45-7","single chemical entity","Component is a metabolite of the substance","2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","","","2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","Not in list","C18H12BrCl2N5O","Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O","InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" "Chlorantraniliprole","","500008-45-7","single chemical entity","Component is a metabolite of the substance","2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","","","2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one","Not in list","C18H12BrCl2N5O","Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O","InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Ireland","Chlorantraniliprole","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.","41431","2013","doi:10.2903/j.efsa.2013.3143" @@ -5008,35 +5008,35 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Chloridazon","216-920-2","1698-60-8","single chemical entity","Component is a metabolite of the substance","5-amino-4-chloro-2-methyl-3(2H)-pyridazinone","605-639-4","17254-80-7","5-amino-4-chloro-2-methylpyridazin-3-one","Not in list","C5H6ClN3O","CN1C(=O)C(=C(C=N1)N)Cl","InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro","in vitro","According to","OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)","No","Acceptable","Rat (as animal)","hepatocytes","","","Not reported","","","yes","without","Negative","","","RMS: Germany","Chloridazon","2004","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon","39307","2007","doi:10.2903/j.efsa.2007.108r" "Chloridazon","216-920-2","1698-60-8","single chemical entity","Component is a metabolite of the substance","5-amino-4-chloro-2-methyl-3(2H)-pyridazinone","605-639-4","17254-80-7","5-amino-4-chloro-2-methylpyridazin-3-one","Not in list","C5H6ClN3O","CN1C(=O)C(=C(C=N1)N)Cl","InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Wistar","","Male","oral: unspecified","20","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Chloridazon","2004","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon","39307","2007","doi:10.2903/j.efsa.2007.108r" "Chloridazon","216-920-2","1698-60-8","single chemical entity","Component is a metabolite of the substance","5-amino-4-chloro-2-methyl-3(2H)-pyridazinone","605-639-4","17254-80-7","5-amino-4-chloro-2-methylpyridazin-3-one","Not in list","C5H6ClN3O","CN1C(=O)C(=C(C=N1)N)Cl","InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Wistar","","Male","oral: unspecified","44","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Germany","Chloridazon","2004","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon","39307","2007","doi:10.2903/j.efsa.2007.108r" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","M45","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","M45","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","M45","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","H17","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","Bacillus subtilis recombination assay","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Bacillus subtilis (as organism)","M45","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is identical to the substance","Chromafenozide","","143807-66-3","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide","Chromafenozide","C24H30N2O3","CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C","InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","intraperitoneal","24","h","yes, concurrent vehicle","not applicable","Negative","","no evidence","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" @@ -5047,30 +5047,30 @@ hydroxychromen-2-one","Bromadiolone","C30H23BrO4","C1=CC=C(C=C1)C(CC(C2=CC=C(C=C "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","without","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N?-tert-butyl-N?-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" -"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N?-tert-butyl-N?-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","without","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","","","N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide","Not in list","C24H30N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes, concurrent vehicle","with","Negative","no information","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" +"Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","","","N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide","Not in list","C24H28N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C","InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","","","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","Not in list","C24H28N2O6","O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","","","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","Not in list","C24H28N2O6","O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" "Chromafenozide","","143807-66-3","single chemical entity","Component is a metabolite of the substance","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","","","3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid","Not in list","C24H28N2O6","O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C","InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Hungary","Chromafenozide","2013","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.","41621","2013","doi:10.2903/j.efsa.2013.3461" @@ -7965,23 +7965,23 @@ fluorophenyl}propanoic acid","Not in list","C13H10Cl2F3N3O3","CC1=NN(C(=O)N1C(F) "Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" "Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" "Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" -"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3?,4?,5?-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","3","Male","oral: unspecified","14","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","without","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","no data","with","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","oral: unspecified","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" +"Fluxapyroxad","","907204-31-3","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","","","3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide","Not in list","C23H20F5N3O7","Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O","InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","3","Male","oral: unspecified","14","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: The United Kingdom","BAS 700 F (Fluxapyroxad)","2011","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)","40935","2012","doi:10.2903/j.efsa.2012.2522" "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is identical to the substance","Thifensulfuron-methyl","616-673-4","79277-27-3","methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate","Thifensulfuron-methyl","C12H13N5O6S2","CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC","InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 97","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is identical to the substance","Thifensulfuron-methyl","616-673-4","79277-27-3","methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate","Thifensulfuron-methyl","C12H13N5O6S2","CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC","InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is identical to the substance","Thifensulfuron-methyl","616-673-4","79277-27-3","methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate","Thifensulfuron-methyl","C12H13N5O6S2","CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC","InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" @@ -8471,8 +8471,8 @@ fluorophenyl}propanoic acid","Not in list","C13H10Cl2F3N3O3","CC1=NN(C(=O)N1C(F) "Bromuconazole","","116255-48-2","single chemical entity","Component is a metabolite of the substance","1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole","","","1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole","Not in list","C13H11Cl2N3O","Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3","InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Belgium","Bromuconazole","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole","40417","2010","doi:10.2903/j.efsa.2010.1704" "Carbosulfan","259-565-9","55285-14-8","single chemical entity","Component is identical to the substance","Carbosulfan","259-565-9","55285-14-8","2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate","Carbosulfan","C20H32N2O3S","CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12","InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: gavage","42","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Belgium","Carbosulfan (Addendum)","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan","40122","2009","doi:10.2903/j.efsa.2009.1354" "Carbosulfan","259-565-9","55285-14-8","single chemical entity","Component is identical to the substance","Carbosulfan","259-565-9","55285-14-8","2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate","Carbosulfan","C20H32N2O3S","CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12","InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","House mouse (as animal)","ICR","10","Male/Female","oral: gavage","18","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: Belgium","Carbosulfan (Addendum)","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan","40122","2009","doi:10.2903/j.efsa.2009.1354" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","Not reported","","","Not reported","","","no data","no data","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" -"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1?,2?-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","","No data","oral: gavage","","","no data","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","Not reported","","","Not reported","","","no data","no data","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" +"Diquat","220-433-0","85-00-7","single chemical entity","Component is identical to the substance","Diquat","220-433-0","85-00-7","6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium","Diquat","C12H12N2+2","C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31","InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","","No data","oral: gavage","","","no data","not applicable","Negative","","","RMS: The United Kingdom","Diquat","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance diquat","42335","2015","doi:10.2903/j.efsa.2015.4308" "Clofentezine","277-728-2","74115-24-5","single chemical entity","Component is identical to the substance","Clofentezine","277-728-2","74115-24-5","3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine","Clofentezine","C14H8Cl2N4","Clc3ccccc3c1nnc(nn1)c2ccccc2Cl","InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Clofentezine (Addendum1)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine","40014","2009","doi:10.2903/j.efsa.2009.269r" "Clofentezine","277-728-2","74115-24-5","single chemical entity","Component is identical to the substance","Clofentezine","277-728-2","74115-24-5","3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine","Clofentezine","C14H8Cl2N4","Clc3ccccc3c1nnc(nn1)c2ccccc2Cl","InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Clofentezine (Addendum1)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine","40014","2009","doi:10.2903/j.efsa.2009.269r" "Clofentezine","277-728-2","74115-24-5","single chemical entity","Component is identical to the substance","Clofentezine","277-728-2","74115-24-5","3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine","Clofentezine","C14H8Cl2N4","Clc3ccccc3c1nnc(nn1)c2ccccc2Cl","InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Clofentezine (Addendum1)","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine","40014","2009","doi:10.2903/j.efsa.2009.269r" @@ -8816,16 +8816,16 @@ fluorophenyl}propanoic acid","Not in list","C13H10Cl2F3N3O3","CC1=NN(C(=O)N1C(F) "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","","","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","Not in list","C12H14N2O2S","CC(C)N2C(=O)SCN(c1ccccc1)C2=O","InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","","","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","Not in list","C12H14N2O2S","CC(C)N2C(=O)SCN(c1ccccc1)C2=O","InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","","","5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione","Not in list","C12H14N2O2S","CC(C)N2C(=O)SCN(c1ccccc1)C2=O","InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide","Not in list","C15H23N3O2","O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C","InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" @@ -8836,16 +8836,16 @@ fluorophenyl}propanoic acid","Not in list","C13H10Cl2F3N3O3","CC1=NN(C(=O)N1C(F) "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","1-phenyl-3-propan-2-ylurea","","19895-44-4","1-phenyl-3-propan-2-ylurea","Not in list","C10H14N2O","CC(C)NC(=O)NC1=CC=CC=C1","InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" -"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N?-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" +"Buprofezin","","69327-76-0","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","","","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","Not in list","C15H23N3OS","O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C","N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Buprofezin (Additional report)","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin","40332","2010","doi:10.2903/j.efsa.2010.1624" "Carfentrazone-ethyl","603-291-8","128639-02-1","single chemical entity","Component is a metabolite of the substance","(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid","","","(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid","Not in list","C13H9ClF3N3O3","O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F","InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","5","Male","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect-toxicokinetic investigations","RMS: Belgium - CoRMS: France","Carfentrazone-ethyl","2016","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl","42612","2016","doi:10.2903/j.efsa.2016.4569" "Carfentrazone-ethyl","603-291-8","128639-02-1","single chemical entity","Component is a metabolite of the substance","(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid","","","2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid","Not in list","C12H8Cl2F3N3O3","O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F","InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian cell micronucleus test","in vitro","According to","OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Belgium - CoRMS: France","Carfentrazone-ethyl","2016","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl","42612","2016","doi:10.2903/j.efsa.2016.4569" "Carfentrazone-ethyl","603-291-8","128639-02-1","single chemical entity","Component is a metabolite of the substance","(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid","","","2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid","Not in list","C12H8Cl2F3N3O3","O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F","InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian cell micronucleus test","in vitro","According to","OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Belgium - CoRMS: France","Carfentrazone-ethyl","2016","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl","42612","2016","doi:10.2903/j.efsa.2016.4569" @@ -13597,26 +13597,26 @@ acid","Imazaquin","C17H17N3O3","CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C" "Metalaxyl-M","615-135-6","70630-17-0","single chemical entity","Component is a metabolite of the substance","N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide","","","N-(2,6-dimethylphenyl)-2-methoxyacetamide","Not in list","C11H15NO2","O=C(Nc1c(C)cccc1C)COC","InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Negative","small colonies","","RMS: Belgium - CoRMS: Greece","Metalaxyl-M","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M","42066","2015","doi:10.2903/j.efsa.2015.3999" "Metalaxyl-M","615-135-6","70630-17-0","single chemical entity","Component is a metabolite of the substance","N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide","","","N-(2,6-dimethylphenyl)-2-methoxyacetamide","Not in list","C11H15NO2","O=C(Nc1c(C)cccc1C)COC","InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Belgium - CoRMS: Greece","Metalaxyl-M","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M","42066","2015","doi:10.2903/j.efsa.2015.3999" "Metalaxyl-M","615-135-6","70630-17-0","single chemical entity","Component is a metabolite of the substance","N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide","","","N-(2,6-dimethylphenyl)-2-methoxyacetamide","Not in list","C11H15NO2","O=C(Nc1c(C)cccc1C)COC","InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Belgium - CoRMS: Greece","Metalaxyl-M","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M","42066","2015","doi:10.2903/j.efsa.2015.3999" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Tif:MAGf(SPF)","16","Male/Female","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","without","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes","with","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" @@ -13630,23 +13630,23 @@ acid","Imazaquin","C17H17N3O3","CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","Equivalent or similar to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No data","Acceptable","Rat (as animal)","Not reported","","No data","intraperitoneal","","","no data","not applicable","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","genome mutation","Drosophila SLRL test","in vivo","Equivalent or similar to","OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)","No data","Acceptable","Drosophila melanogaster (as animal)","Not reported","","Male","Not reported","3","D","no data","not applicable","Negative","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" "Imazalil","252-615-0","35554-44-0","single chemical entity","Component is identical to the substance","Imazalil","252-615-0","35554-44-0","1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole","Imazalil","C14H14Cl2N2O","C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl","InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","single cell gel/comet assay in mammalian cells for detection of DNA damage","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes","no data","Positive","","","RMS: The Netherlands - CoRMS: Spain","Imazalil","2009","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil","40256","2010","doi:10.2903/j.efsa.2010.1526" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1538","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","72","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","48","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","24","h","yes, concurrent vehicle","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-hydroxy-terbuthylazine","","","4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol","Desethyl-hydroxy-terbuthylazine","C7H13N5O","Nc1nc(NC(C)(C)C)nc(O)n1","InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-hydroxy-terbuthylazine","","","4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol","Desethyl-hydroxy-terbuthylazine","C7H13N5O","Nc1nc(NC(C)(C)C)nc(O)n1","InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 102","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-hydroxy-terbuthylazine","","","4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol","Desethyl-hydroxy-terbuthylazine","C7H13N5O","Nc1nc(NC(C)(C)C)nc(O)n1","InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" @@ -13709,16 +13709,16 @@ acid","Imazaquin","C17H17N3O3","CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" -"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N?-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" +"Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is identical to the substance","Terbuthylazine","227-637-9","5915-41-3","N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine","Terbuthylazine","C9H16ClN5","CCNc1nc(Cl)nc(NC(C)(C)C)n1","InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" "Terbuthylazine","227-637-9","5915-41-3","single chemical entity","Component is a metabolite of the substance","Desethyl-terbuthylazine","","30125-63-4","2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine","Terbuthylazine, Desethyl-","C7H12ClN5","CC(C)(C)NC1=NC(=NC(=N1)N)Cl","InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: The United Kingdom","Terbuthylazine (Additional report)","2010","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine","40553","2011","doi:10.2903/j.efsa.2011.1969" @@ -15603,14 +15603,14 @@ butanoyl]amino]propanoate","Valifenalate","C19H27ClN2O5","CC(C)[C@@H](C(=O)NC(CC "Spirodiclofen","","148477-71-8","single chemical entity","Component is identical to the substance","Spirodiclofen","","148477-71-8","3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate","Spirodiclofen","C21H24Cl2O4","O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1","InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","10","Male/Female","intraperitoneal","48","h","yes","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The Netherlands","Spirodiclofen","2004","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance spirodiclofen","40031","2009","doi:10.2903/j.efsa.2009.339r" "Spirodiclofen","","148477-71-8","single chemical entity","Component is identical to the substance","Spirodiclofen","","148477-71-8","3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate","Spirodiclofen","C21H24Cl2O4","O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1","InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","10","Male/Female","intraperitoneal","24","h","yes","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The Netherlands","Spirodiclofen","2004","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance spirodiclofen","40031","2009","doi:10.2903/j.efsa.2009.339r" "Spirodiclofen","","148477-71-8","single chemical entity","Component is identical to the substance","Spirodiclofen","","148477-71-8","3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate","Spirodiclofen","C21H24Cl2O4","O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1","InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Not reported","10","Male/Female","intraperitoneal","16","h","yes","not applicable","Negative","","direct evidence-cytotoxicity","RMS: The Netherlands","Spirodiclofen","2004","Conclusion on Pesticides Peer Review","EFSA","Peer review of the pesticide risk assessment of the active substance spirodiclofen","40031","2009","doi:10.2903/j.efsa.2009.339r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" @@ -15648,30 +15648,30 @@ butanoyl]amino]propanoate","Valifenalate","C19H27ClN2O5","CC(C)[C@@H](C(=O)NC(CC "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vivo","No guideline followed","Not reported","Not applicable","Acceptable","Rat (as animal)","Wistar","","No data","oral: feed","12","D","yes","not applicable","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vivo","No guideline followed","Not reported","Not applicable","Acceptable","Rat (as animal)","Wistar","","No data","oral: feed","12","D","yes","not applicable","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is identical to the substance","Tolylfluanid","211-986-9","731-27-1","N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline","Tolylfluanid","C10H13Cl2FN2O2S2","CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C","InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3","organic","compound","PubChem canonical SMILES","PubChem InChI","DNA damage and/or repair","other","in vivo","No guideline followed","Not reported","Not applicable","Acceptable","Rat (as animal)","Wistar","","No data","oral: feed","12","D","yes","not applicable","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N?-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(YA-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" -"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(YA-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST","","","N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide","Not in list","C9H14N2O3S","O=S(=O)(Nc1ccc(cc1)CO)N(C)C","InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","4-Hydroxymethyl-DMST-glucoside","","","N,N-dimethyl-N?-[(4-(ñ-D-glucopyranosyl)-methylphenyl]sulfamide","Not in list","C16H26N2O8S","CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2","InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" +"Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST-glucoside","","","N,N-dimethyl-N?-[[2-(ñ-D-glucopyranosyl)-4-methyl]phenyl]sulfamide","Not in list","C15H24N2O8S","CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O","InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST","","","N,N-dimethyl-N?-[(2-hydroxy-4-methyl)-phenyl]sulfamide","Not in list","C9H14N2O3S","Oc1cc(C)ccc1NS(=O)(=O)N(C)C","InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST","","","N,N-dimethyl-N?-[(2-hydroxy-4-methyl)-phenyl]sulfamide","Not in list","C9H14N2O3S","Oc1cc(C)ccc1NS(=O)(=O)N(C)C","InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" "Tolylfluanid","211-986-9","731-27-1","single chemical entity","Component is a metabolite of the substance","2-Hydroxyphenyl-DMST","","","N,N-dimethyl-N?-[(2-hydroxy-4-methyl)-phenyl]sulfamide","Not in list","C9H14N2O3S","Oc1cc(C)ccc1NS(=O)(=O)N(C)C","InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Finland","Tolylfluanid","2003","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid","38463","2005","doi:10.2903/j.efsa.2005.29r" @@ -16135,31 +16135,31 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Fenpropimorph","266-719-9","67564-91-4","single chemical entity","Component is identical to the substance","Fenpropimorph","266-719-9","67564-91-4","(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine","Fenpropimorph","C20H33NO","CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1","InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male/Female","intraperitoneal","48","h","yes","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: Germany","Fenpropimorph","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph","39658","2008","doi:10.2903/j.efsa.2008.144r" "Fenpropimorph","266-719-9","67564-91-4","single chemical entity","Component is identical to the substance","Fenpropimorph","266-719-9","67564-91-4","(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine","Fenpropimorph","C20H33NO","CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1","InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male/Female","intraperitoneal","24","h","yes","not applicable","Negative","","indirect evidence-systemic toxicity","RMS: Germany","Fenpropimorph","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph","39658","2008","doi:10.2903/j.efsa.2008.144r" "Fenpropimorph","266-719-9","67564-91-4","single chemical entity","Component is identical to the substance","Fenpropimorph","266-719-9","67564-91-4","(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine","Fenpropimorph","C20H33NO","CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1","InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+","organic","compound","Other","Other","chromosome aberration","dominant lethal assay","in vivo","According to","OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)","No","Acceptable","House mouse (as animal)","NMRI","40","Male","intraperitoneal","18","D","yes, concurrent vehicle","not applicable","Negative","","","RMS: Germany","Fenpropimorph","2007","Conclusion on Pesticides Peer Review","EFSA","Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph","39658","2008","doi:10.2903/j.efsa.2008.144r" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N?-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","intraperitoneal","24","h","yes","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" -"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N?-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","lung fibroblasts (V79)","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is identical to the substance","Flubendiamide","","272451-65-7","3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide","Flubendiamide","C23H22F7IN2O4S","CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C","InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","5","Male","intraperitoneal","24","h","yes","not applicable","Negative","","direct evidence-cytotoxicity$indirect evidence-systemic toxicity","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" +"Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O4S","Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" "Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O5S","O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" "Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O5S","O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" "Flubendiamide","","272451-65-7","single chemical entity","Component is a metabolite of the substance","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","","","N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide","Not in list","C23H23F7N2O5S","O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F","InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Greece","Flubendiamide","2008","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.","41526","2013","doi:10.2903/j.efsa.2013.3298" @@ -16734,29 +16734,29 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Ferric phosphate","233-149-7","10045-86-0","single chemical entity","Component is identical to the substance","Ferric phosphate","233-149-7","10045-86-0","iron(3+);phosphate","Not in list","FePO4","[O-]P(=O)([O-])[O-].[Fe+3]","InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3","inorganic","compound","PubChem canonical SMILES","PubChem InChI","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany - CoRMS: Poland","Ferric phosphate (Final addendum to Renewal Assessment Report)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate","42033","2015","doi:10.2903/j.efsa.2015.3973" "Ferric phosphate","233-149-7","10045-86-0","single chemical entity","Component is identical to the substance","Ferric phosphate","233-149-7","10045-86-0","iron(3+);phosphate","Not in list","FePO4","[O-]P(=O)([O-])[O-].[Fe+3]","InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3","inorganic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","10","Male/Female","oral: gavage","48","h","yes","not applicable","Negative","","no evidence","RMS: Germany - CoRMS: Poland","Ferric phosphate (Final addendum to Renewal Assessment Report)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate","42033","2015","doi:10.2903/j.efsa.2015.3973" "Ferric phosphate","233-149-7","10045-86-0","single chemical entity","Component is identical to the substance","Ferric phosphate","233-149-7","10045-86-0","iron(3+);phosphate","Not in list","FePO4","[O-]P(=O)([O-])[O-].[Fe+3]","InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3","inorganic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","10","Male/Female","oral: gavage","24","h","yes","not applicable","Negative","","no evidence","RMS: Germany - CoRMS: Poland","Ferric phosphate (Final addendum to Renewal Assessment Report)","2014","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate","42033","2015","doi:10.2903/j.efsa.2015.3973" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Ambiguous","small colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Ambiguous","small colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Ambiguous","large colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Ambiguous","large colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","12","Male/Female","oral: unspecified","48","h","yes","not applicable","Negative","","no evidence","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","12","Male/Female","oral: unspecified","24","h","yes","not applicable","Negative","","no evidence","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","4","Male","oral: unspecified","16","h","yes","not applicable","Ambiguous","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","4","Male/Female","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" -"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1?-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","4","Male/Female","oral: gavage","4","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","According to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Ambiguous","small colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Ambiguous","small colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","without","Ambiguous","large colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","Equivalent or similar to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","Yes","Acceptable","House mouse (as animal)","lymphoma L5178Y cells","","","Not reported","","","yes","with","Ambiguous","large colonies","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","12","Male/Female","oral: unspecified","48","h","yes","not applicable","Negative","","no evidence","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","NMRI","12","Male/Female","oral: unspecified","24","h","yes","not applicable","Negative","","no evidence","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Sprague-Dawley","4","Male","oral: unspecified","16","h","yes","not applicable","Ambiguous","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","4","Male/Female","oral: gavage","16","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" +"Sedaxane","","874967-67-6","mixture or formulation","Component is part of a mixture or forumlation","Sedaxane","","874967-67-6","N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide","Not in list","C18H19F2N3O","FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1","InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)","organic","compound","Other","Other","DNA damage and/or repair","unscheduled DNA synthesis","in vivo","According to","OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)","No","Acceptable","Rat (as animal)","Wistar","4","Male/Female","oral: gavage","4","h","yes, concurrent vehicle","not applicable","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" "Sedaxane","","874967-67-6","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" "Sedaxane","","874967-67-6","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" "Sedaxane","","874967-67-6","single chemical entity","Component is a metabolite of the substance","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","","","3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid","Not in list","C5H4F2N2O2","FC(F)c1nncc1C(=O)O","InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: France","Sedaxane","2012","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane","41304","2013","doi:10.2903/j.efsa.2013.3057" @@ -17196,40 +17196,40 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Carbendazim","234-232-0","10605-21-7","single chemical entity","Component is part of a group but not included in the group assessment","Thiophanate-methyl","245-740-7","23564-05-8","methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate","Thiophanate-methyl","C12H14N4O4S2","COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC","InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian cell micronucleus test","in vitro","According to","OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Carbendazim, Benomyl, Thiophanate-methyl (Addendum)","2002","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim","40310","2010","doi:10.2903/j.efsa.2010.1598" "Carbendazim","234-232-0","10605-21-7","single chemical entity","Component is part of a group but not included in the group assessment","Thiophanate-methyl","245-740-7","23564-05-8","methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate","Thiophanate-methyl","C12H14N4O4S2","COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC","InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","in vitro mammalian cell micronucleus test","in vitro","According to","OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)","No","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","yes, concurrent vehicle","without","Positive","","","RMS: Germany","Carbendazim, Benomyl, Thiophanate-methyl (Addendum)","2002","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim","40310","2010","doi:10.2903/j.efsa.2010.1598" "Carbendazim","234-232-0","10605-21-7","single chemical entity","Component is part of a group but not included in the group assessment","Thiophanate-methyl","245-740-7","23564-05-8","methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate","Thiophanate-methyl","C12H14N4O4S2","COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC","InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)","organic","compound","PubChem canonical SMILES","PubChem InChI","chromosome aberration","other","in vitro","No guideline available","Not reported","Not applicable","Acceptable","Human (as organism)","lymphocytes","","","Not reported","","","no data","not applicable","Positive","","","RMS: Germany","Carbendazim, Benomyl, Thiophanate-methyl (Addendum)","2002","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim","40310","2010","doi:10.2903/j.efsa.2010.1598" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","DNA damage and/or repair","DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro","in vitro","According to","OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)","No","Acceptable","Rat (as animal)","hepatocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","48","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","24","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N?-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","6","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N?-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","in vitro mammalian chromosome aberration test","in vitro","Equivalent or similar to","OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)","Yes","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","gene mutation","mammalian cell gene mutation assay","in vitro","According to","OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)","No","Acceptable","Hamster (as animal)","CHO","","","Not reported","","","yes","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","DNA damage and/or repair","DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro","in vitro","According to","OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)","No","Acceptable","Rat (as animal)","hepatocytes","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","48","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","24","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is identical to the substance","Tebufenozide","","112410-23-8","N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide","Tebufenozide","C22H28N2O2","O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1","InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)","organic","compound","Other","Other","chromosome aberration","chromosome aberration assay","in vivo","According to","OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)","No","Acceptable","Rat (as animal)","Sprague-Dawley","10","Male/Female","oral: gavage","6","h","yes","not applicable","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","","","N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide","Not in list","C22H26N2O3","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C","InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent no treatment","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent no treatment","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent no treatment","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" @@ -17240,26 +17240,26 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent no treatment","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent no treatment","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","","","4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid","Not in list","C21H24N2O4","Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C","InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent no treatment","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide","Not in list","C22H28N2O3","Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C","InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates","","","","Not in list","","","","organic","no structure","","","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","","","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","Not in list","C22H22N2O7","O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O","InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A pKM 101","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","","","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","Not in list","C22H22N2O7","O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O","InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","","","5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid","Not in list","C22H22N2O7","O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O","InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" @@ -17278,26 +17278,26 @@ ethyl carbonate","Not in list","C21H27NO5","CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3 "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","","","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","Not in list","C22H26N2O4","O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","","","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","Not in list","C22H26N2O4","O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","","","[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid","Not in list","C22H26N2O4","O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N?-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" -"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N?-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","","","N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide","Not in list","C22H28N2O3","OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C","InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Escherichia coli (as organism)","WP2 uvr A","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 100","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 1535","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" +"Tebufenozide","","112410-23-8","single chemical entity","Component is a metabolite of the substance","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","","","N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide","Not in list","C22H26N2O3","CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C","InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","According to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","No","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tebufenozide","2005","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide","40526","2010","doi:10.2903/j.efsa.2010.1871" "Tefluthrin","","79538-32-2","single chemical entity","Component is identical to the substance","Tefluthrin","","79538-32-2","2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate","Tefluthrin","C17H14ClF7O2","O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F","InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tefluthrin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin","40521","2010","doi:10.2903/j.efsa.2010.1709" "Tefluthrin","","79538-32-2","single chemical entity","Component is identical to the substance","Tefluthrin","","79538-32-2","2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate","Tefluthrin","C17H14ClF7O2","O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F","InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 1537","","","Not reported","","","yes, concurrent vehicle","without","Negative","","","RMS: Germany","Tefluthrin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin","40521","2010","doi:10.2903/j.efsa.2010.1709" "Tefluthrin","","79538-32-2","single chemical entity","Component is identical to the substance","Tefluthrin","","79538-32-2","2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate","Tefluthrin","C17H14ClF7O2","O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F","InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-","organic","compound","Other","Other","gene mutation","bacterial reverse mutation assay","in vitro","Equivalent or similar to","OECD Guideline 471 (Bacterial Reverse Mutation Assay)","Yes","Acceptable","Salmonella typhimurium (as organism)","TA 98","","","Not reported","","","yes, concurrent vehicle","with","Negative","","","RMS: Germany","Tefluthrin","2006","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin","40521","2010","doi:10.2903/j.efsa.2010.1709" @@ -18376,7 +18376,7 @@ sulfanylcarbamoyl]oxyethanimidothioate","Thiodicarb","C10H18N4O4S3","CC(=NOC(=O) "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is a metabolite of the substance","methyl 3-sulfamoylthiophene-2-carboxylate","","","methyl 3-sulfamoylthiophene-2-carboxylate","Not in list","C6H7NO4S2","O=S(N)(=O)c1ccsc1C(=O)OC","InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","48","h","yes","not applicable","Negative","","no evidence","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" "Thifensulfuron-methyl","616-673-4","79277-27-3","single chemical entity","Component is a metabolite of the substance","methyl 3-sulfamoylthiophene-2-carboxylate","","","methyl 3-sulfamoylthiophene-2-carboxylate","Not in list","C6H7NO4S2","O=S(N)(=O)c1ccsc1C(=O)OC","InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)","organic","compound","Other","Other","chromosome aberration","Mammalian erythrocyte micronucleus test","in vivo","According to","OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)","No","Acceptable","House mouse (as animal)","Swiss","10","Male/Female","oral: gavage","72","h","yes","not applicable","Negative","","no evidence","RMS: The United Kingdom","Thifensulfuron-methyl","2015","Conclusion on Pesticides Peer Review","EFSA","Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl","42208","2015","doi:10.2903/j.efsa.2015.4201" "Name","Type","Description","isNullable","isRecordUniqueIdentifier","Catalogue Code","Last update" -"GUIDELINE_QUALIFIER","Character","Indicates how strict the guideline given in the subsequent field ?Guideline? was followed or whether no guideline was used or available/required",,"FALSE",,"26/10/2015" +"GUIDELINE_QUALIFIER","Character","Indicates how strict the guideline given in the subsequent field 'Guideline' was followed or whether no guideline was used or available/required",,"FALSE",,"26/10/2015" "GENOTOXGUIDELINEFULLTXT","Character","Full description for the guideline followed",,"FALSE",,"10-27-19" "DEVIATION","Character","Indicates whether a genotoxicity study contains deviations from the standard test protocol",,"FALSE",,"26/10/2015" "GLP_COMPL","Character","Indicates whether a GLP certificate or compliance statement is available",,"FALSE",,"26/10/2015" |