@prefix :        <https://toxbank-dev.in-silico.ch/0/> .
@prefix dc:      <http://purl.org/dc/elements/1.1/> .
@prefix rdfs:    <http://www.w3.org/2000/01/rdf-schema#> .
@prefix tb:      <http://onto.toxbank.net/api/> .
@prefix foaf:    <http://xmlns.com/foaf/0.1/> .
@prefix isa:     <http://onto.toxbank.net/isa/> .
@prefix owl:     <http://www.w3.org/2002/07/owl#> .
@prefix xsd:     <http://www.w3.org/2001/XMLSchema#> .
@prefix rdf:     <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dcterms:  <http://purl.org/dc/terms/> .

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      a       owl:ObjectProperty ;
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:MN264
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.109" ;
      isa:hasInputNode :MN2131 ;
      isa:hasOutputNode :MN1446 ;
      isa:hasStudy :S2 .

:MN2016
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.38:out:0" ;
      isa:hasMaterial :M2335 ;
      isa:hasStudy :S2 .

:MN1906
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.0.2.7:in:0" ;
      isa:hasMaterial :M2418 ;
      isa:hasStudy :S2 .

:OE3192
      a       isa:OntologyEntry .

:FV3340
      a       isa:FactorValue .

:DAN518
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.28" ;
      isa:hasInputNode :MN1510 ;
      isa:hasOutputNode :DN2067 ;
      isa:hasStudy :S2 .

:FV2634
      a       isa:FactorValue .

:M3650
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.07-aliquot9" .

:MN2160
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.9:out:0" ;
      isa:hasMaterial :M2291 ;
      isa:hasStudy :S2 .

:M2918
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.07-aliquot5" .

:D3700
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3934" ;
      isa:hasFactorValue :FV3703 , :FV3702 ;
      dcterms:title "SCAN:MEXP:3934" .

:D3127
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC5_Carbon_0.10_Internal_2_1.txt" ;
      dcterms:title "JIC5_Carbon_0.10_Internal_2_1.txt" .

:MN118
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.34" ;
      isa:hasInputNode :MN1697 ;
      isa:hasOutputNode :MN1599 ;
      isa:hasProtocolApplication
              :PA2560 ;
      isa:hasStudy :S2 .

:MN991
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.68" ;
      isa:hasInputNode :MN1572 ;
      isa:hasOutputNode :MN2104 ;
      isa:hasProtocolApplication
              :PA3931 ;
      isa:hasStudy :S2 .

:MN1331
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.19:out:0" ;
      isa:hasMaterial :M2463 ;
      isa:hasStudy :S2 .

:A1158
      a       isa:Assay .

:A1212
      a       isa:Assay .

:MN1995
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.14:out:0" ;
      isa:hasMaterial :M2446 ;
      isa:hasStudy :S2 .

:MN1086
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.10" ;
      isa:hasInputNode :MN2181 ;
      isa:hasOutputNode :MN2183 ;
      isa:hasStudy :S2 .

:MN195
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.80" ;
      isa:hasInputNode :MN2127 ;
      isa:hasOutputNode :MN1997 ;
      isa:hasProtocolApplication
              :PA2767 ;
      isa:hasStudy :S2 .

:D3670
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3929" ;
      isa:hasFactorValue :FV3672 , :FV3673 ;
      dcterms:title "SCAN:MEXP:3929" .

:DN1890
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.21:out:0" ;
      isa:hasData :D3670 ;
      isa:hasStudy :S2 .

:PA2546
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1110 .

:PA3845
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN263
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.9" ;
      isa:hasInputNode :MN1746 ;
      isa:hasOutputNode :MN1382 ;
      isa:hasStudy :S2 .

:PA2833
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2264
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.C-0.1-aliquot2" .

:FV3678
      a       isa:FactorValue .

:DN2019
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.2:out:0" ;
      isa:hasData :D2612 ;
      isa:hasStudy :S2 .

:PA2256
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:MN117
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.39" ;
      isa:hasInputNode :MN2177 ;
      isa:hasOutputNode :MN2136 ;
      isa:hasProtocolApplication
              :PA2557 ;
      isa:hasStudy :S2 .

:OE3805
      a       isa:OntologyEntry .

:PA3491
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN911
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.97" ;
      isa:hasInputNode :MN1464 ;
      isa:hasOutputNode :MN1361 ;
      isa:hasStudy :S2 .

:FV2709
      a       isa:FactorValue .

:MN1996
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.51:out:0" ;
      isa:hasMaterial :M2380 ;
      isa:hasStudy :S2 .

:MN1087
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.11" ;
      isa:hasInputNode :MN2116 ;
      isa:hasOutputNode :MN1482 ;
      isa:hasStudy :S2 .

:A1159
      a       isa:Assay .

:A1211
      a       isa:Assay .

:MN262
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.1" ;
      isa:hasInputNode :MN1596 ;
      isa:hasOutputNode :MN1375 ;
      isa:hasStudy :S2 .

:MN192
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.33" ;
      isa:hasInputNode :MN1326 ;
      isa:hasOutputNode :MN1873 ;
      isa:hasProtocolApplication
              :PA2761 ;
      isa:hasStudy :S2 .

:MN1904
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.96:out:0" ;
      isa:hasMaterial :M3458 ;
      isa:hasStudy :S2 .

:FV3342
      a       isa:FactorValue .

:M2263
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.C-0.1-aliquot2" .

:MN89
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.29" ;
      isa:hasInputNode :MN1502 ;
      isa:hasOutputNode :MN1962 ;
      isa:hasProtocolApplication
              :PA2476 ;
      isa:hasStudy :S2 .

:MN1088
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.12" ;
      isa:hasInputNode :MN1694 ;
      isa:hasOutputNode :MN2017 ;
      isa:hasStudy :S2 .

:D3068
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC106_GlucoseO2_0.20_External_1_1.txt" ;
      dcterms:title "JIC106_GlucoseO2_0.20_External_1_1.txt" .

:A1210
      a       isa:Assay .

:D3129
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC64_Nitrogen_0.07_External_1_2.txt" ;
      dcterms:title "JIC64_Nitrogen_0.07_External_1_2.txt" .

:DN1811
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.13:out:0" ;
      isa:hasData :D3545 ;
      isa:hasStudy :S2 .

:MN116
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.38" ;
      isa:hasInputNode :MN1364 ;
      isa:hasOutputNode :MN1522 ;
      isa:hasProtocolApplication
              :PA2554 ;
      isa:hasStudy :S2 .

:MN910
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.89" ;
      isa:hasInputNode :MN1810 ;
      isa:hasOutputNode :MN1533 ;
      isa:hasStudy :S2 .

:MN2013
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.12:out:0" ;
      isa:hasMaterial :M2545 ;
      isa:hasStudy :S1 .

:MN261
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.0" ;
      isa:hasInputNode :MN1933 ;
      isa:hasOutputNode :MN1473 ;
      isa:hasStudy :S2 .

:MN193
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.30" ;
      isa:hasInputNode :MN1448 ;
      isa:hasOutputNode :MN1892 ;
      isa:hasProtocolApplication
              :PA2763 ;
      isa:hasStudy :S2 .

:MN1997
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.80:out:0" ;
      isa:hasMaterial :M2769 ;
      isa:hasStudy :S2 .

:DN1669
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.8:out:0" ;
      isa:hasData :D3209 ;
      isa:hasStudy :S2 .

:MN1998
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.46:out:0" ;
      isa:hasMaterial :M2339 ;
      isa:hasStudy :S2 .

:MN1903
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.46:out:0" ;
      isa:hasMaterial :M2278 ;
      isa:hasStudy :S2 .

:FV3341
      a       isa:FactorValue .

:M2998
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC54_GlucoseO2_0.20_Internal_3_1" .

:PA2541
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1110 .

:A1217
      a       isa:Assay .

:DPN411
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.2" ;
      isa:hasInputNode :DN1816 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN1081
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.16" ;
      isa:hasInputNode :MN1869 ;
      isa:hasOutputNode :MN1587 ;
      isa:hasStudy :S2 .

:D3275
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_raw_data:a_microarray.NZ_4hrs_Drug_Sample_1_Labelled_Hyb11_Scan11" ;
      dcterms:title "NZ_4hrs_Drug_Sample_1_Labelled_Hyb11_Scan11" .

:MN198
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.34" ;
      isa:hasInputNode :MN1599 ;
      isa:hasOutputNode :MN1505 ;
      isa:hasProtocolApplication
              :PA2774 ;
      isa:hasStudy :S2 .

:MN268
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.5" ;
      isa:hasInputNode :MN1596 ;
      isa:hasOutputNode :MN1375 ;
      isa:hasStudy :S2 .

:MN115
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.8" ;
      isa:hasInputNode :MN2144 ;
      isa:hasOutputNode :MN1861 ;
      isa:hasProtocolApplication
              :PA2551 ;
      isa:hasStudy :S1 .

:MN1334
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.153:out:0" ;
      isa:hasMaterial :M2810 ;
      isa:hasStudy :S2 .

:DN1812
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.82:out:0" ;
      isa:hasData :D3009 ;
      isa:hasStudy :S2 .

:A1153
      a       isa:Assay .

:PA3420
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:M2269
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.C-0.07-aliquot3" .

:MN1448
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.30:out:0" ;
      isa:hasMaterial :M2526 ;
      isa:hasStudy :S2 .

:M2636
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3912" .

:M2914
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC93_Ethanol_0.07_External_3_1" .

:PA3848
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN1769
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.41:out:0" ;
      isa:hasMaterial :M2308 ;
      isa:hasStudy :S2 .

:MN1902
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.90:out:0" ;
      isa:hasMaterial :M2230 ;
      isa:hasStudy :S2 .

:M3051
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC37_Ethanol_0.07_Internal_1_2" .

:DPN344
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.29" ;
      isa:hasInputNode :DN1641 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:A1216
      a       isa:Assay .

:DAN512
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.25" ;
      isa:hasInputNode :MN2162 ;
      isa:hasOutputNode :DN1899 ;
      isa:hasStudy :S2 .

:D3062
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC38_Ethanol_0.07_Internal_2_1.txt" ;
      dcterms:title "JIC38_Ethanol_0.07_Internal_2_1.txt" .

:DN2012
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.7:out:0" ;
      isa:hasData :D3305 ;
      isa:hasStudy :S1 .

:MN1082
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.17" ;
      isa:hasInputNode :MN1854 ;
      isa:hasOutputNode :MN2145 ;
      isa:hasStudy :S2 .

:DPN412
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.3" ;
      isa:hasInputNode :DN1817 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN199
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.35" ;
      isa:hasInputNode :MN1607 ;
      isa:hasOutputNode :MN1684 ;
      isa:hasProtocolApplication
              :PA2776 ;
      isa:hasStudy :S2 .

:PA2259
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN114
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.11" ;
      isa:hasInputNode :MN1704 ;
      isa:hasOutputNode :MN1994 ;
      isa:hasProtocolApplication
              :PA2549 ;
      isa:hasStudy :S1 .

:MN1335
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.128:in:0" ;
      isa:hasMaterial :M3821 ;
      isa:hasStudy :S2 .

:MN267
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.6" ;
      isa:hasInputNode :MN1514 ;
      isa:hasOutputNode :MN2010 ;
      isa:hasStudy :S2 .

:A1154
      a       isa:Assay .

:MN2164
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.80:out:0" ;
      isa:hasMaterial :M2245 ;
      isa:hasStudy :S2 .

:D3338
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_2hrs_Vehicle_Sample_2_Labelled_Hyb10_Scan10" ;
      isa:hasFactorValue :FV3340 , :FV3341 , :FV3342 ;
      dcterms:title "NZ_2hrs_Vehicle_Sample_2_Labelled_Hyb10_Scan10" .

:MN2011
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.47:out:0" ;
      isa:hasMaterial :M2275 ;
      isa:hasStudy :S2 .

:PA3909
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:M2913
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.07-aliquot6" .

:MN1449
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.10:out:0" ;
      isa:hasMaterial :M2430 ;
      isa:hasStudy :S1 .

:OE3195
      a       isa:OntologyEntry .

:PA3849
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DPN142
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.9" ;
      isa:hasInputNode :DN1757 ;
      isa:hasOutputNode :DN1527 ;
      isa:hasStudy :S2 .

:MN1083
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.18" ;
      isa:hasInputNode :MN1374 ;
      isa:hasOutputNode :MN1735 ;
      isa:hasStudy :S2 .

:MN1992
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.42:out:0" ;
      isa:hasMaterial :M3421 ;
      isa:hasStudy :S2 .

:A1215
      a       isa:Assay .

:MN266
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.7" ;
      isa:hasInputNode :MN1911 ;
      isa:hasOutputNode :MN2101 ;
      isa:hasStudy :S2 .

:DPN347
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.34" ;
      isa:hasInputNode :DN1658 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN196
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.36" ;
      isa:hasInputNode :MN1612 ;
      isa:hasOutputNode :MN1414 ;
      isa:hasProtocolApplication
              :PA2770 ;
      isa:hasStudy :S2 .

:DN2015
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.17:out:0" ;
      isa:hasData :D3557 ;
      isa:hasStudy :S2 .

:MN2223
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.77:out:0" ;
      isa:hasMaterial :M2783 ;
      isa:hasStudy :S2 .

:PA3422
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN2010
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.6:out:0" ;
      isa:hasMaterial :M2905 ;
      isa:hasStudy :S2 .

:MN1332
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.2:out:0" ;
      isa:hasMaterial :M3502 ;
      isa:hasStudy :S2 .

:A1155
      a       isa:Assay .

:D3277
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_4hrs_Drug_Sample_1_Labelled_Hyb11_Scan11" ;
      isa:hasFactorValue :FV3279 , :FV3280 , :FV3281 ;
      dcterms:title "NZ_4hrs_Drug_Sample_1_Labelled_Hyb11_Scan11" .

:MN113
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.9" ;
      isa:hasInputNode :MN1560 ;
      isa:hasOutputNode :MN2064 ;
      isa:hasProtocolApplication
              :PA2546 ;
      isa:hasStudy :S1 .

:MN1445
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.97:in:0" ;
      isa:hasMaterial :M3785 ;
      isa:hasStudy :S2 .

:M2917
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC91_Ethanol_0.07_External_1_3" .

:M2916
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC94_Ethanol_0.10_External_1_1" .

:M3656
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.07-aliquot8" .

:FV3346
      a       isa:FactorValue .

:PA2830
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2267
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.C-0.07-aliquot1" .

:FV3677
      a       isa:FactorValue .

:M2529
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.P-0.1-aliquot4" .

:M2993
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC101_GlucoseO2_0.07_External_2_1" .

:DAN516
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.27" ;
      isa:hasInputNode :MN1725 ;
      isa:hasOutputNode :DN1778 ;
      isa:hasStudy :S2 .

:DN2014
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.3:out:0" ;
      isa:hasData :D3277 ;
      isa:hasStudy :S1 .

:DAN514
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.26" ;
      isa:hasInputNode :MN1886 ;
      isa:hasOutputNode :DN1320 ;
      isa:hasStudy :S2 .

:MN265
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.8" ;
      isa:hasInputNode :MN1914 ;
      isa:hasOutputNode :MN2057 ;
      isa:hasStudy :S2 .

:DPN410
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.1" ;
      isa:hasInputNode :DN2135 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN197
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.37" ;
      isa:hasInputNode :MN1316 ;
      isa:hasOutputNode :MN1385 ;
      isa:hasProtocolApplication
              :PA2772 ;
      isa:hasStudy :S2 .

:DPN143
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.8" ;
      isa:hasInputNode :DN2128 ;
      isa:hasOutputNode :DN2043 ;
      isa:hasStudy :S2 .

:PA2544
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1102 .

:MN1993
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.75:out:0" ;
      isa:hasMaterial :M3172 ;
      isa:hasStudy :S2 .

:MN112
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.12" ;
      isa:hasInputNode :MN1704 ;
      isa:hasOutputNode :MN2013 ;
      isa:hasProtocolApplication
              :PA2544 ;
      isa:hasStudy :S1 .

:MN1084
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1350 ;
      isa:hasOutputNode :MN1353 ;
      isa:hasStudy :S2 .

:MN2224
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.31:out:0" ;
      isa:hasMaterial :M2529 ;
      isa:hasStudy :S2 .

:DPN346
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.30" ;
      isa:hasInputNode :DN1978 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:A1156
      a       isa:Assay .

:A1214
      a       isa:Assay .

:MN2162
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

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      a       isa:MaterialNode ;
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      isa:hasMaterial :M2902 ;
      isa:hasStudy :S2 .

:M2266
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.C-0.07-aliquot1" .

:OE3197
      a       isa:OntologyEntry .

:M2915
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.1-aliquot4" .

:FV3345
      a       isa:FactorValue .

:M2379
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.2-aliquot7" .

:D3706
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3932" ;
      isa:hasFactorValue :FV3709 , :FV3708 ;
      dcterms:title "SCAN:MEXP:3932" .

:FV2633
      a       isa:FactorValue .

:PA2781
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:OE3570
      a       isa:OntologyEntry .

:FV3682
      a       isa:FactorValue .

:DN2032
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.16:out:0" ;
      isa:hasData :D3560 ;
      isa:hasStudy :S2 .

:MN1090
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.14" ;
      isa:hasInputNode :MN2214 ;
      isa:hasOutputNode :MN1462 ;
      isa:hasStudy :S2 .

:MN905
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.146" ;
      isa:hasInputNode :MN1384 ;
      isa:hasOutputNode :MN1893 ;
      isa:hasProtocolApplication
              :PA3905 ;
      isa:hasStudy :S2 .

:FV2597
      a       isa:FactorValue .

:M3433
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_proteome.S-0.2" .

:DPN352
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.31" ;
      isa:hasInputNode :DN2001 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DPN703
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.23" ;
      isa:hasInputNode :DN2132 ;
      isa:hasOutputNode :DN1447 ;
      isa:hasStudy :S2 .

:FV3806
      a       isa:FactorValue .

:DPN926
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.100" ;
      isa:hasInputNode :DN1877 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:OE2708
      a       isa:OntologyEntry .

:D3284
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_2hrs_Drug_Sample_1_Labelled_Hyb7_Scan7" ;
      isa:hasFactorValue :FV3288 , :FV3287 , :FV3286 ;
      dcterms:title "NZ_2hrs_Drug_Sample_1_Labelled_Hyb7_Scan7" .

:MN999
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.43" ;
      isa:hasInputNode :MN1646 ;
      isa:hasOutputNode :MN1340 ;
      isa:hasStudy :S2 .

:MN1777
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.35:out:0" ;
      isa:hasMaterial :M3768 ;
      isa:hasStudy :S2 .

:MN2222
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.84:out:0" ;
      isa:hasMaterial :M3902 ;
      isa:hasStudy :S2 .

:DAN520
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.29" ;
      isa:hasInputNode :MN2070 ;
      isa:hasOutputNode :DN1641 ;
      isa:hasStudy :S2 .

isa:MaterialNode
      rdfs:subClassOf isa:Node .

:M2850
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3922" .

:FV3683
      a       isa:FactorValue .

:MN906
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.87" ;
      isa:hasInputNode :MN1656 ;
      isa:hasOutputNode :MN2088 ;
      isa:hasStudy :S2 .

:DN2020
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.106:out:0" ;
      isa:hasData :D3823 ;
      isa:hasStudy :S2 .

:FV2598
      a       isa:FactorValue .

:M2910
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC41_Ethanol_0.10_Internal_2_1" .

:PA2772
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:PA3497
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:FV3807
      a       isa:FactorValue .

:PA3412
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:DPN353
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.39" ;
      isa:hasInputNode :DN1722 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:OE3349
      a       isa:OntologyEntry .

:DN1899
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.25:out:0" ;
      isa:hasData :D3059 ;
      isa:hasStudy :S2 .

:MN1776
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.30:out:0" ;
      isa:hasMaterial :M2330 ;
      isa:hasStudy :S2 .

:MN998
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.42" ;
      isa:hasInputNode :MN1646 ;
      isa:hasOutputNode :MN1340 ;
      isa:hasStudy :S2 .

:M3337
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC81_Phosphate_0.20_External_3_1" .

:MN2221
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.31:out:0" ;
      isa:hasMaterial :M3267 ;
      isa:hasStudy :S2 .

:MN907
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.147" ;
      isa:hasInputNode :MN1384 ;
      isa:hasOutputNode :MN1926 ;
      isa:hasProtocolApplication
              :PA3907 ;
      isa:hasStudy :S2 .

:M2911
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.1-aliquot3" .

:DPN701
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.22" ;
      isa:hasInputNode :DN1403 ;
      isa:hasOutputNode :DN2150 ;
      isa:hasStudy :S2 .

:OE3231
      a       isa:OntologyEntry .

isa:OntologyEntry
      rdfs:subClassOf isa:Annotatable .

:OE2706
      a       isa:OntologyEntry .

:DN1345
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.32:out:0" ;
      isa:hasData :D3745 ;
      isa:hasStudy :S2 .

:MN2220
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.46:out:0" ;
      isa:hasMaterial :M2338 ;
      isa:hasStudy :S2 .

:DPN928
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.101" ;
      isa:hasInputNode :DN2035 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DN2035
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.101:out:0" ;
      isa:hasData :D3843 ;
      isa:hasStudy :S2 .

:M3336
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC80_Phosphate_0.20_External_2_1" .

:MN997
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.45" ;
      isa:hasInputNode :MN1761 ;
      isa:hasOutputNode :MN1620 ;
      isa:hasStudy :S2 .

:MN189
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.38" ;
      isa:hasInputNode :MN1522 ;
      isa:hasOutputNode :MN1315 ;
      isa:hasProtocolApplication
              :PA2755 ;
      isa:hasStudy :S2 .

:DN1896
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.7:out:0" ;
      isa:hasData :D2639 ;
      isa:hasStudy :S2 .

:MN1779
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.67:out:0" ;
      isa:hasMaterial :M2754 ;
      isa:hasStudy :S2 .

:MN908
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.88" ;
      isa:hasInputNode :MN2125 ;
      isa:hasOutputNode :MN1550 ;
      isa:hasStudy :S2 .

:PA3639
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:M3434
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_proteome.JC_S-0.2" .

:M2912
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC42_Ethanol_0.10_Internal_3_1" .

:MN1668
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.37:out:0" ;
      isa:hasMaterial :M2570 ;
      isa:hasStudy :S2 .

:PA2774
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:PA3414
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN1667
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.34:out:0" ;
      isa:hasMaterial :M3238 ;
      isa:hasStudy :S2 .

:PA3499
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:DN1451
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.9:out:0" ;
      isa:hasData :D3328 ;
      isa:hasStudy :S1 .

:MN996
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.44" ;
      isa:hasInputNode :MN2108 ;
      isa:hasOutputNode :MN1660 ;
      isa:hasStudy :S2 .

:M3335
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC79_Phosphate_0.20_External_1_1" .

:PA2551
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1110 .

:DN1897
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.107:out:0" ;
      isa:hasData :D3855 ;
      isa:hasStudy :S2 .

:MN188
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.67" ;
      isa:hasInputNode :MN2056 ;
      isa:hasOutputNode :MN1779 ;
      isa:hasProtocolApplication
              :PA2752 ;
      isa:hasStudy :S2 .

:PA2485
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:MN1909
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.43:out:0" ;
      isa:hasMaterial :M2299 ;
      isa:hasStudy :S2 .

:FV3802
      a       isa:FactorValue .

:FV3742
      a       isa:FactorValue .

:DN1809
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.0:out:0" ;
      isa:hasData :D3214 ;
      isa:hasStudy :S2 .

:M3437
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_proteome.JC_P-0.2" .

:OE3576
      a       isa:OntologyEntry .

:MN1988
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.0:out:0" ;
      isa:hasMaterial :M2388 ;
      isa:hasStudy :S1 .

:DPN661
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.36" ;
      isa:hasInputNode :DN2161 ;
      isa:hasOutputNode :DN1928 ;
      isa:hasStudy :S2 .

:MN900
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.85" ;
      isa:hasInputNode :MN1889 ;
      isa:hasOutputNode :MN1731 ;
      isa:hasStudy :S2 .

:MN271
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.104" ;
      isa:hasInputNode :MN1541 ;
      isa:hasOutputNode :MN2107 ;
      isa:hasStudy :S2 .

:MN1773
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.51:out:0" ;
      isa:hasMaterial :M3818 ;
      isa:hasStudy :S2 .

:MN995
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.47" ;
      isa:hasInputNode :MN1971 ;
      isa:hasOutputNode :MN2069 ;
      isa:hasStudy :S2 .

:A1220
      a       isa:Assay .

:MN2098
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.30:out:0" ;
      isa:hasMaterial :M3265 ;
      isa:hasStudy :S2 .

:MN1553
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.13:out:0" ;
      isa:hasMaterial :M2442 ;
      isa:hasStudy :S2 .

:M2260
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.07-aliquot7" .

:DN1347
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.31:out:0" ;
      isa:hasData :D3740 ;
      isa:hasStudy :S2 .

:PA2776
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:DPN662
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.39" ;
      isa:hasInputNode :DN1338 ;
      isa:hasOutputNode :DN2008 ;
      isa:hasStudy :S2 .

:M3436
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_proteome.P-0.2" .

:M2854
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3919" .

:DAN820
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.100" ;
      isa:hasInputNode :MN1442 ;
      isa:hasOutputNode :DN1877 ;
      isa:hasStudy :S2 .

:DN1808
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.24:out:0" ;
      isa:hasData :D3706 ;
      isa:hasStudy :S2 .

:MN902
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.83" ;
      isa:hasInputNode :MN2200 ;
      isa:hasOutputNode :MN1408 ;
      isa:hasStudy :S2 .

:MN901
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.84" ;
      isa:hasInputNode :MN2222 ;
      isa:hasOutputNode :MN1805 ;
      isa:hasStudy :S2 .

:A1149
      a       isa:Assay .

:MN1772
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.8:out:0" ;
      isa:hasMaterial :M3510 ;
      isa:hasStudy :S2 .

:MN272
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.101" ;
      isa:hasInputNode :MN1452 ;
      isa:hasOutputNode :MN2033 ;
      isa:hasStudy :S2 .

:PA3493
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN994
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.46" ;
      isa:hasInputNode :MN1998 ;
      isa:hasOutputNode :MN1764 ;
      isa:hasStudy :S2 .

:OE3688
      a       isa:OntologyEntry .

:D3057
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC37_Ethanol_0.07_Internal_1_3.txt" ;
      dcterms:title "JIC37_Ethanol_0.07_Internal_1_3.txt" .

:MN2097
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.13:out:0" ;
      isa:hasMaterial :M2856 ;
      isa:hasStudy :S2 .

:MN1665
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.1:out:0" ;
      isa:hasMaterial :M2664 ;
      isa:hasStudy :S2 .

:A1221
      a       isa:Assay .

:M2261
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.P-0.07-aliquot7" .

:MN1552
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.6:out:0" ;
      isa:hasMaterial :M2258 ;
      isa:hasStudy :S2 .

isa:Study
      rdfs:subClassOf isa:HASREFERENCES .

:PA3416
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

isa:hasSampleField
      a       owl:FunctionalProperty , owl:DatatypeProperty ;
      rdfs:domain isa:Node .

:DN1662
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.80:out:0" ;
      isa:hasData :D3019 ;
      isa:hasStudy :S2 .

:OE2997
      a       isa:OntologyEntry .

:M2748
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.C-0.1-aliquot6" .

:MN903
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.82" ;
      isa:hasInputNode :MN1627 ;
      isa:hasOutputNode :MN1880 ;
      isa:hasStudy :S2 .

:DN2030
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.5:out:0" ;
      isa:hasData :D3230 ;
      isa:hasStudy :S2 .

:M3439
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_proteome.Pool3" .

:MN993
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      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.2:out:0" ;
      isa:hasMaterial :M2662 ;
      isa:hasStudy :S2 .

:PA3850
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DPN425
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.65" ;
      isa:hasInputNode :DN1410 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:M3121
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC55_Carbon_0.07_External_1_1" .

:PA2316
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2481
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.P-0.07-aliquot4" .

:A1163
      a       isa:Assay .

:D3687
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3933" ;
      isa:hasFactorValue :FV3690 , :FV3689 ;
      dcterms:title "SCAN:MEXP:3933" .

:M3903
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.G-0.2-aliquot5" .

:OE3076
      a       isa:OntologyEntry .

:D3609
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3943" ;
      isa:hasFactorValue :FV3612 , :FV3611 ;
      dcterms:title "SCAN:MEXP:3943" .

:M3193
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC58_Carbon_0.10_External_1_1" .

:MN70
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.0.2.8" ;
      isa:hasInputNode :MN1649 ;
      isa:hasOutputNode :MN1836 ;
      isa:hasProtocolApplication
              :PA2420 ;
      isa:hasStudy :S2 .

:MN1869
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.16:out:0" ;
      isa:hasMaterial :M2523 ;
      isa:hasStudy :S2 .

:FV2641
      a       isa:FactorValue .

:M2760
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3940" .

:M3266
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC10_Nitrogen_0.07_Internal_1_3" .

:DN1771
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.56:out:0" ;
      isa:hasData :D3137 ;
      isa:hasStudy :S2 .

:PA3795
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN2178
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.40:out:0" ;
      isa:hasMaterial :M3211 ;
      isa:hasStudy :S2 .

:M2480
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.P-0.07-aliquot4" .

:DAN484
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.17" ;
      isa:hasInputNode :MN1313 ;
      isa:hasOutputNode :DN1488 ;
      isa:hasStudy :S2 .

:A1164
      a       isa:Assay .

:OE3138
      a       isa:OntologyEntry .

:MN1430
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.118:out:0" ;
      isa:hasMaterial :M3488 ;
      isa:hasStudy :S2 .

:M3902
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.G-0.2-aliquot6" .

:M2539
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:labelled_extract:a_microarray.NZ_0hrs_Sample_2_Labelled" .

:OE3135
      a       isa:OntologyEntry .

:MN1866
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.3:out:0" ;
      isa:hasMaterial :M2404 ;
      isa:hasStudy :S1 .

:MN71
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.12" ;
      isa:hasInputNode :MN2207 ;
      isa:hasOutputNode :MN2024 ;
      isa:hasProtocolApplication
              :PA2423 ;
      isa:hasStudy :S1 .

:M2483
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.P-0.1-aliquot1" .

:DPN427
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.66" ;
      isa:hasInputNode :DN1847 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:PA2686
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN1326
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.33:out:0" ;
      isa:hasMaterial :M2535 ;
      isa:hasStudy :S2 .

:A1161
      a       isa:Assay .

:MN1431
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.135:in:0" ;
      isa:hasMaterial :M3837 ;
      isa:hasStudy :S2 .

:M3901
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.G-0.07-aliquot1" .

:M2389
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:hybridization:a_microarray.NZ_0hrs_Sample_1_Labelled_Hyb1" .

:M3752
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:source:culture12" .

:OE3187
      a       isa:OntologyEntry .

:OE3074
      a       isa:OntologyEntry .

:MN1867
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.117:out:0" ;
      isa:hasMaterial :M3494 ;
      isa:hasStudy :S2 .

isa:Data
      rdfs:subClassOf isa:Accessible .

:M2762
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3941" .

:MN72
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.11" ;
      isa:hasInputNode :MN1766 ;
      isa:hasOutputNode :MN2113 ;
      isa:hasProtocolApplication
              :PA2426 ;
      isa:hasStudy :S1 .

:DAN486
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.18" ;
      isa:hasInputNode :MN2153 ;
      isa:hasOutputNode :DN1579 ;
      isa:hasStudy :S2 .

:PA3797
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:D3070
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC80_Phosphate_0.20_External_2_1.txt" ;
      dcterms:title "JIC80_Phosphate_0.20_External_2_1.txt" .

:A1162
      a       isa:Assay .

:MN259
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.2" ;
      isa:hasInputNode :MN1468 ;
      isa:hasOutputNode :MN1782 ;
      isa:hasStudy :S2 .

:MN1432
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.17:out:0" ;
      isa:hasMaterial :M2454 ;
      isa:hasStudy :S2 .

:DPN429
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.67" ;
      isa:hasInputNode :DN2184 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN73
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.10" ;
      isa:hasInputNode :MN1449 ;
      isa:hasOutputNode :MN1642 ;
      isa:hasProtocolApplication
              :PA2429 ;
      isa:hasStudy :S1 .

:FV3221
      a       isa:FactorValue .

:MN1329
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.56:out:0" ;
      isa:hasMaterial :M3476 ;
      isa:hasStudy :S2 .

:DAN247
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.11" ;
      isa:hasInputNode :MN2113 ;
      isa:hasOutputNode :DN2159 ;
      isa:hasStudy :S1 .

:PA3792
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:PA3559
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1106 .

:MN1079
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.85" ;
      isa:hasInputNode :MN1367 ;
      isa:hasOutputNode :MN1404 ;
      isa:hasProtocolApplication
              :PA3973 ;
      isa:hasStudy :S2 .

:DAN620
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.23" ;
      isa:hasInputNode :MN1832 ;
      isa:hasOutputNode :DN2132 ;
      isa:hasStudy :S2 .

:MN74
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.10" ;
      isa:hasInputNode :MN1536 ;
      isa:hasOutputNode :MN1863 ;
      isa:hasProtocolApplication
              :PA2432 ;
      isa:hasStudy :S2 .

:M2484
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.P-0.1-aliquot1" .

:M2534
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.P-0.2-aliquot2" .

:FV3220
      a       isa:FactorValue .

:OE2630
      a       isa:OntologyEntry .

:D3605
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3944" ;
      isa:hasFactorValue :FV3608 , :FV3607 ;
      dcterms:title "SCAN:MEXP:3944" .

:PA2932
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1102 .

:M3750
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.N-0.2-aliquot9" .

isa:Node
      rdfs:subClassOf isa:GraphElement .

:OE3707
      a       isa:OntologyEntry .

:D3137
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC3_Carbon_0.07_Internal_3_1.txt" ;
      dcterms:title "JIC3_Carbon_0.07_Internal_3_1.txt" .

:PA2265
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:DAN248
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.10" ;
      isa:hasInputNode :MN1642 ;
      isa:hasOutputNode :DN1796 ;
      isa:hasStudy :S1 .

:M2383
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.C-0.07-aliquot8" .

:A1160
      a       isa:Assay .

:M3126
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC5_Carbon_0.10_Internal_2_1" .

:DAN488
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.15" ;
      isa:hasInputNode :MN1844 ;
      isa:hasOutputNode :DN1730 ;
      isa:hasStudy :S2 .

:OE3071
      a       isa:OntologyEntry .

:M2487
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.P-0.07-aliquot2" .

:MN75
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.11" ;
      isa:hasInputNode :MN1950 ;
      isa:hasOutputNode :MN1729 ;
      isa:hasProtocolApplication
              :PA2435 ;
      isa:hasStudy :S2 .

:M2535
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.P-0.2-aliquot2" .

:M2386
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.C-0.07-aliquot9" .

:D3134
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC66_Nitrogen_0.07_External_3_1.txt" ;
      dcterms:title "JIC66_Nitrogen_0.07_External_3_1.txt" .

:DAN245
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.13" ;
      isa:hasInputNode :MN1835 ;
      isa:hasOutputNode :DN1739 ;
      isa:hasStudy :S1 .

:MN1077
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.84" ;
      isa:hasInputNode :MN1509 ;
      isa:hasOutputNode :MN1649 ;
      isa:hasProtocolApplication
              :PA3972 ;
      isa:hasStudy :S2 .

:PA2262
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:PA3794
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:OE3811
      a       isa:OntologyEntry .

:PA2538
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1110 .

:M2486
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.P-0.07-aliquot2" .

:DAN509
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.24" ;
      isa:hasInputNode :MN1337 ;
      isa:hasOutputNode :DN2123 ;
      isa:hasStudy :S2 .

:MN76
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.12" ;
      isa:hasInputNode :MN1415 ;
      isa:hasOutputNode :MN1647 ;
      isa:hasProtocolApplication
              :PA2438 ;
      isa:hasStudy :S2 .

:PA2930
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1102 .

:M2385
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.07-aliquot9" .

:DAN246
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.12" ;
      isa:hasInputNode :MN2024 ;
      isa:hasOutputNode :DN1639 ;
      isa:hasStudy :S1 .

:MN870
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.154" ;
      isa:hasInputNode :MN1381 ;
      isa:hasOutputNode :MN2018 ;
      isa:hasProtocolApplication
              :PA3888 ;
      isa:hasStudy :S2 .

:DN2008
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.39:out:0" ;
      isa:hasData :D3609 ;
      isa:hasStudy :S2 .

:MN1078
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.17" ;
      isa:hasInputNode :MN1814 ;
      isa:hasOutputNode :MN1322 ;
      isa:hasStudy :S2 .

:PA2313
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M3046
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC37_Ethanol_0.07_Internal_1_1" .

:MN2215
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.57:out:0" ;
      isa:hasMaterial :M3829 ;
      isa:hasStudy :S2 .

:DN1991
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.4:out:0" ;
      isa:hasData :D3270 ;
      isa:hasStudy :S1 .

:MN2026
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.82:out:0" ;
      isa:hasMaterial :M2822 ;
      isa:hasStudy :S2 .

:MN1075
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.15" ;
      isa:hasInputNode :MN1814 ;
      isa:hasOutputNode :MN1322 ;
      isa:hasStudy :S2 .

:MN250
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.110" ;
      isa:hasInputNode :MN1664 ;
      isa:hasOutputNode :MN1378 ;
      isa:hasStudy :S2 .

:FV2648
      a       isa:FactorValue .

:PA2268
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:DPN134
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.2" ;
      isa:hasInputNode :DN2019 ;
      isa:hasOutputNode :DN1759 ;
      isa:hasStudy :S2 .

:MN105
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.30" ;
      isa:hasInputNode :MN1828 ;
      isa:hasOutputNode :MN1448 ;
      isa:hasProtocolApplication
              :PA2524 ;
      isa:hasStudy :S2 .

:M2909
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.1-aliquot2" .

:MN2171
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.39:out:0" ;
      isa:hasMaterial :M2758 ;
      isa:hasStudy :S2 .

:M2275
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.S-0.2-aliquot4" .

:D3715
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3935" ;
      isa:hasFactorValue :FV3717 , :FV3718 ;
      dcterms:title "SCAN:MEXP:3935" .

:MN1438
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.107:out:0" ;
      isa:hasMaterial :M2914 ;
      isa:hasStudy :S2 .

:MN77
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.13" ;
      isa:hasInputNode :MN1553 ;
      isa:hasOutputNode :MN1651 ;
      isa:hasProtocolApplication
              :PA2441 ;
      isa:hasStudy :S2 .

:M2985
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.E-0.1-aliquot2" .

:DAN508
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.23" ;
      isa:hasInputNode :MN1623 ;
      isa:hasOutputNode :DN1673 ;
      isa:hasStudy :S2 .

:M2489
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.P-0.07-aliquot3" .

:FV3330
      a       isa:FactorValue .

:OE3182
      a       isa:OntologyEntry .

:PA2536
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1102 .

:A1222
      a       isa:Assay .

:D3680
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3927" ;
      isa:hasFactorValue :FV3682 , :FV3683 ;
      dcterms:title "SCAN:MEXP:3927" .

:MN1985
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.0:out:0" ;
      isa:hasMaterial :M3504 ;
      isa:hasStudy :S2 .

:MN2025
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.45:out:0" ;
      isa:hasMaterial :M3427 ;
      isa:hasStudy :S2 .

:MN1076
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.83" ;
      isa:hasInputNode :MN1509 ;
      isa:hasOutputNode :MN1499 ;
      isa:hasProtocolApplication
              :PA3971 ;
      isa:hasStudy :S2 .

:PA2823
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2908
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC91_Ethanol_0.07_External_1_2" .

:D3601
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3939" ;
      isa:hasFactorValue :FV3604 , :FV3603 ;
      dcterms:title "SCAN:MEXP:3939" .

:MN104
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.16" ;
      isa:hasInputNode :MN1433 ;
      isa:hasOutputNode :MN1869 ;
      isa:hasProtocolApplication
              :PA2521 ;
      isa:hasStudy :S2 .

:DPN135
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.5" ;
      isa:hasInputNode :DN1748 ;
      isa:hasOutputNode :DN1531 ;
      isa:hasStudy :S2 .

:MN78
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.14" ;
      isa:hasInputNode :MN1685 ;
      isa:hasOutputNode :MN1995 ;
      isa:hasProtocolApplication
              :PA2444 ;
      isa:hasStudy :S2 .

:FV3530
      a       isa:FactorValue .

:M3419
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.2-aliquot3" .

:A1225
      a       isa:Assay .

:DN2005
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.59:out:0" ;
      isa:hasData :D3149 ;
      isa:hasStudy :S2 .

:MN1073
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.16" ;
      isa:hasInputNode :MN1814 ;
      isa:hasOutputNode :MN1322 ;
      isa:hasStudy :S2 .

:A1169
      a       isa:Assay .

:DN1678
      a       isa:DataNode ;
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      a       isa:MaterialNode ;
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      isa:hasMaterial :M2394 ;
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:FV2659
      a       isa:FactorValue .

:MN306
      a       isa:MaterialProcessing ;
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              :PA2977 ;
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      a       isa:Material ;
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:PA3790
      a       isa:ProtocolApplication ;
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      a       isa:MaterialNode ;
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isa:hasInputNode
      a       owl:ObjectProperty ;
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:MN107
      a       isa:MaterialProcessing ;
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              :PA2530 ;
      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1631 ;
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              :PA2447 ;
      isa:hasStudy :S2 .

:DAN506
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN1740 ;
      isa:hasOutputNode :DN2218 ;
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      a       isa:MaterialNode ;
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      a       isa:MaterialProcessing ;
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      isa:hasProtocolApplication
              :PA3970 ;
      isa:hasStudy :S2 .

:OE3701
      a       isa:OntologyEntry .

:MN2027
      a       isa:MaterialNode ;
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      a       isa:DataNode ;
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      isa:hasData :D3826 ;
      isa:hasStudy :S2 .

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      a       isa:Material ;
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:MN2172
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2720 ;
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      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.100" ;
      isa:hasInputNode :MN1421 ;
      isa:hasOutputNode :MN1496 ;
      isa:hasProtocolApplication
              :PA2980 ;
      isa:hasStudy :S2 .

:D3078
      a       isa:Data ;
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      dcterms:title "JIC108_GlucoseO2_0.20_External_3_1.txt" .

:MN106
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.31" ;
      isa:hasInputNode :MN1853 ;
      isa:hasOutputNode :MN2224 ;
      isa:hasProtocolApplication
              :PA2527 ;
      isa:hasStudy :S2 .

:D3139
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC65_Nitrogen_0.07_External_2_1.txt" ;
      dcterms:title "JIC65_Nitrogen_0.07_External_2_1.txt" .

:M2988
      a       isa:Material ;
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:M2276
      a       isa:Material ;
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:MN308
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1696 ;
      isa:hasOutputNode :MN2193 ;
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              :PA2983 ;
      isa:hasStudy :S2 .

:M2905
      a       isa:Material ;
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:PA2821
      a       isa:ProtocolApplication ;
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:MN2219
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.22:out:0" ;
      isa:hasMaterial :M2722 ;
      isa:hasStudy :S2 .

:M3417
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.2-aliquot4" .

:FV2647
      a       isa:FactorValue .

:MN2022
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.8:out:0" ;
      isa:hasMaterial :M2816 ;
      isa:hasStudy :S2 .

:PA3410
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN2175
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.6:out:0" ;
      isa:hasMaterial :M2543 ;
      isa:hasStudy :S1 .

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      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.92:out:0" ;
      isa:hasMaterial :M2522 ;
      isa:hasStudy :S2 .

:D3289
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_raw_data:a_microarray.NZ_1hrs_Drug_Sample_1_Labelled_Hyb3_Scan3" ;
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:DN1802
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.20:out:0" ;
      isa:hasData :D3664 ;
      isa:hasStudy :S2 .

:MN101
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.12" ;
      isa:hasInputNode :MN1677 ;
      isa:hasOutputNode :MN1694 ;
      isa:hasProtocolApplication
              :PA2512 ;
      isa:hasStudy :S2 .

:MN1071
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.88" ;
      isa:hasInputNode :MN1367 ;
      isa:hasOutputNode :MN1784 ;
      isa:hasProtocolApplication
              :PA3968 ;
      isa:hasStudy :S2 .

:DPN421
      a       isa:DataProcessing ;
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      isa:hasInputNode :DN1523 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:A1227
      a       isa:Assay .

:M2590
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.S-0.1-aliquot5" .

:A1167
      a       isa:Assay .

:MN2211
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.89:out:0" ;
      isa:hasMaterial :M2840 ;
      isa:hasStudy :S2 .

:D3075
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC81_Phosphate_0.20_External_3_1.txt" ;
      dcterms:title "JIC81_Phosphate_0.20_External_3_1.txt" .

:M2981
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:E-0.1-aliquot1" .

:MN9  a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.24" ;
      isa:hasInputNode :MN1999 ;
      isa:hasOutputNode :MN1882 ;
      isa:hasProtocolApplication
              :PA2238 ;
      isa:hasStudy :S2 .

:M2904
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.S-0.1-aliquot6" .

:FV3689
      a       isa:FactorValue .

:M3644
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.1-aliquot8" .

:FV3533
      a       isa:FactorValue .

:M2279
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.S-0.2-aliquot3" .

:MN1648
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.26:out:0" ;
      isa:hasMaterial :M2796 ;
      isa:hasStudy :S2 .

:MN1321
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.1:out:0" ;
      isa:hasMaterial :M2921 ;
      isa:hasStudy :S1 .

:MN2021
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2511 ;
      isa:hasStudy :S2 .

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      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.49:out:0" ;
      isa:hasMaterial :M3796 ;
      isa:hasStudy :S2 .

:DN1803
      a       isa:DataNode ;
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      isa:hasData :D3581 ;
      isa:hasStudy :S2 .

:MN305
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1590 ;
      isa:hasOutputNode :MN1670 ;
      isa:hasProtocolApplication
              :PA2974 ;
      isa:hasStudy :S2 .

:MN1434
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.7:out:0" ;
      isa:hasMaterial :M2539 ;
      isa:hasStudy :S1 .

:FV3607
      a       isa:FactorValue .

:A1226
      a       isa:Assay .

:DPN358
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.36" ;
      isa:hasInputNode :DN1865 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DN2039
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.102:out:0" ;
      isa:hasData :D3839 ;
      isa:hasStudy :S2 .

:MN1072
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.89" ;
      isa:hasInputNode :MN1367 ;
      isa:hasOutputNode :MN1650 ;
      isa:hasProtocolApplication
              :PA3969 ;
      isa:hasStudy :S2 .

:DPN131
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.3" ;
      isa:hasInputNode :DN1425 ;
      isa:hasOutputNode :DN1325 ;
      isa:hasStudy :S2 .

:MN100
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.13" ;
      isa:hasInputNode :MN1486 ;
      isa:hasOutputNode :MN2021 ;
      isa:hasProtocolApplication
              :PA2509 ;
      isa:hasStudy :S2 .

:MN1981
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.5:out:0" ;
      isa:hasMaterial :M2397 ;
      isa:hasStudy :S1 .

:MN2212
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.37:out:0" ;
      isa:hasMaterial :M3763 ;
      isa:hasStudy :S2 .

:A1168
      a       isa:Assay .

:M2982
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.E-0.1-aliquot1" .

:PA2319
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:FV3534
      a       isa:FactorValue .

:M2903
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.S-0.2-aliquot5" .

:OE3185
      a       isa:OntologyEntry .

:MN1649
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.84:out:0" ;
      isa:hasMaterial :M2421 ;
      isa:hasStudy :S2 .

:M2278
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.S-0.2-aliquot3" .

:MN256
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.100" ;
      isa:hasInputNode :MN1440 ;
      isa:hasOutputNode :MN1442 ;
      isa:hasStudy :S2 .

:FV3608
      a       isa:FactorValue .

:MN103
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.17" ;
      isa:hasInputNode :MN1584 ;
      isa:hasOutputNode :MN1854 ;
      isa:hasProtocolApplication
              :PA2518 ;
      isa:hasStudy :S2 .

:MN1322
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.13:out:0" ;
      isa:hasMaterial :M3617 ;
      isa:hasStudy :S2 .

:A1165
      a       isa:Assay .

:MN2177
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.39:out:0" ;
      isa:hasMaterial :M2558 ;
      isa:hasStudy :S2 .

:M2592
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3916" .

:MN2024
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.12:out:0" ;
      isa:hasMaterial :M2425 ;
      isa:hasStudy :S1 .

:D3073
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC107_GlucoseO2_0.20_External_2_1.txt" ;
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:DN2001
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.31:out:0" ;
      isa:hasData :D3094 ;
      isa:hasStudy :S2 .

:DPN423
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.64" ;
      isa:hasInputNode :DN2170 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:A1229
      a       isa:Assay .

:MN7  a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.29" ;
      isa:hasInputNode :MN1742 ;
      isa:hasOutputNode :MN1878 ;
      isa:hasProtocolApplication
              :PA2232 ;
      isa:hasStudy :S2 .

:FV2642
      a       isa:FactorValue .

:FV3332
      a       isa:FactorValue .

:PA2792
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:DPN710
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.27" ;
      isa:hasInputNode :DN1678 ;
      isa:hasOutputNode :DN1539 ;
      isa:hasStudy :S2 .

:OE3079
      a       isa:OntologyEntry .

:M2902
      a       isa:Material ;
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:D3799
      a       isa:Data ;
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      isa:hasFactorValue :FV3802 , :FV3801 ;
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:MN102
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.18" ;
      isa:hasInputNode :MN2065 ;
      isa:hasOutputNode :MN1374 ;
      isa:hasProtocolApplication
              :PA2515 ;
      isa:hasStudy :S2 .

:MN1436
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.129:out:0" ;
      isa:hasMaterial :M2876 ;
      isa:hasStudy :S2 .

:A1166
      a       isa:Assay .

:D3326
      a       isa:Data ;
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:MN2176
      a       isa:MaterialNode ;
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      isa:hasMaterial :M3685 ;
      isa:hasStudy :S2 .

:MN2023
      a       isa:MaterialNode ;
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      isa:hasMaterial :M3842 ;
      isa:hasStudy :S2 .

:PA2530
      a       isa:ProtocolApplication ;
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:DPN356
      a       isa:DataProcessing ;
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      isa:hasInputNode :DN1973 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN1070
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1367 ;
      isa:hasOutputNode :MN1953 ;
      isa:hasProtocolApplication
              :PA3967 ;
      isa:hasStudy :S2 .

:A1228
      a       isa:Assay .

:MN2214
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2508 ;
      isa:hasStudy :S2 .

:DN2037
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.40:out:0" ;
      isa:hasData :D3569 ;
      isa:hasStudy :S2 .

:MN1758
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.39:out:0" ;
      isa:hasMaterial :M2315 ;
      isa:hasStudy :S2 .

:FV3331
      a       isa:FactorValue .

:MN8  a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.23" ;
      isa:hasInputNode :MN2104 ;
      isa:hasOutputNode :MN1350 ;
      isa:hasProtocolApplication
              :PA2235 ;
      isa:hasStudy :S2 .

:M2871
      a       isa:Material ;
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:M2984
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:E-0.1-aliquot2" .

:FV2654
      a       isa:FactorValue .

:D3209
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC88_Sulphate_0.20_External_1_1.txt" ;
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:OE3245
      a       isa:OntologyEntry .

:M2901
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.1-aliquot5" .

:MN1437
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.35:out:0" ;
      isa:hasMaterial :M3235 ;
      isa:hasStudy :S2 .

:D3328
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_4hrs_Drug_Sample_2_Labelled_Hyb12_Scan12" ;
      isa:hasFactorValue :FV3331 , :FV3332 , :FV3330 ;
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:PA3626
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:M3423
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.1-aliquot2" .

:MN1657
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.16:out:0" ;
      isa:hasMaterial :M2451 ;
      isa:hasStudy :S2 .

:FV3696
      a       isa:FactorValue .

:DPN713
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.26" ;
      isa:hasInputNode :DN1716 ;
      isa:hasOutputNode :DN1797 ;
      isa:hasStudy :S2 .

:FV3603
      a       isa:FactorValue .

:MN1768
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.61:out:0" ;
      isa:hasMaterial :M3859 ;
      isa:hasStudy :S2 .

:FV2587
      a       isa:FactorValue .

:MN6  a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.28" ;
      isa:hasInputNode :MN1902 ;
      isa:hasOutputNode :MN1687 ;
      isa:hasProtocolApplication
              :PA2229 ;
      isa:hasStudy :S2 .

:DPN366
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.42" ;
      isa:hasInputNode :DN1645 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1572 ;
      isa:hasOutputNode :MN1677 ;
      isa:hasProtocolApplication
              :PA3925 ;
      isa:hasStudy :S2 .

:DN1884
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.6:out:0" ;
      isa:hasData :D3311 ;
      isa:hasStudy :S1 .

:MN1080
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.15" ;
      isa:hasInputNode :MN1330 ;
      isa:hasOutputNode :MN1460 ;
      isa:hasStudy :S2 .

:DN1673
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.23:out:0" ;
      isa:hasData :D3031 ;
      isa:hasStudy :S2 .

:D3298
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_1hrs_Drug_Sample_2_Labelled_Hyb4_Scan4" ;
      isa:hasFactorValue :FV3300 , :FV3302 , :FV3301 ;
      dcterms:title "NZ_1hrs_Drug_Sample_2_Labelled_Hyb4_Scan4" .

:DN1333
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.6:out:0" ;
      isa:hasData :D2643 ;
      isa:hasStudy :S2 .

:D3203
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC85_Sulphate_0.10_External_1_1.txt" ;
      dcterms:title "JIC85_Sulphate_0.10_External_1_1.txt" .

isa:DataNode
      rdfs:subClassOf isa:Node .

:MN1656
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.87:out:0" ;
      isa:hasMaterial :M3906 ;
      isa:hasStudy :S2 .

:MN301
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.106" ;
      isa:hasInputNode :MN1941 ;
      isa:hasOutputNode :MN1732 ;
      isa:hasProtocolApplication
              :PA2963 ;
      isa:hasStudy :S2 .

:FV3697
      a       isa:FactorValue .

:M2900
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.S-0.2-aliquot6" .

:PA2786
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2860
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3917" .

:OE3561
      a       isa:OntologyEntry .

:MN1767
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.36:out:0" ;
      isa:hasMaterial :M2353 ;
      isa:hasStudy :S2 .

:MN5  a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.27" ;
      isa:hasInputNode :MN1650 ;
      isa:hasOutputNode :MN2190 ;
      isa:hasProtocolApplication
              :PA2226 ;
      isa:hasStudy :S2 .

:MN984
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1572 ;
      isa:hasOutputNode :MN1958 ;
      isa:hasProtocolApplication
              :PA3924 ;
      isa:hasStudy :S2 .

:MN1766
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2427 ;
      isa:hasStudy :S1 .

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      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.4:out:0" ;
      isa:hasData :D3268 ;
      isa:hasStudy :S1 .

:D2655
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3916" ;
      dcterms:title "SCAN:MEXP:3916" .

:MN879
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.107" ;
      isa:hasInputNode :MN1363 ;
      isa:hasOutputNode :MN1801 ;
      isa:hasStudy :S2 .

:PA3402
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:PA2473
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:MN300
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.107" ;
      isa:hasInputNode :MN1707 ;
      isa:hasOutputNode :MN1363 ;
      isa:hasProtocolApplication
              :PA2960 ;
      isa:hasStudy :S2 .

:MN1655
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.4:out:0" ;
      isa:hasMaterial :M2927 ;
      isa:hasStudy :S1 .

:M3421
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.1-aliquot1" .

:MN1659
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.40:out:0" ;
      isa:hasMaterial :M2294 ;
      isa:hasStudy :S2 .

:MN639
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.9" ;
      isa:hasInputNode :MN1921 ;
      isa:hasOutputNode :MN1560 ;
      isa:hasProtocolApplication
              :PA3550 ;
      isa:hasStudy :S1 .

:M2863
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.G-0.2-aliquot2" .

:DAN618
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.9" ;
      isa:hasInputNode :MN2202 ;
      isa:hasOutputNode :DN1940 ;
      isa:hasStudy :S2 .

:MN987
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.78" ;
      isa:hasInputNode :MN1509 ;
      isa:hasOutputNode :MN1999 ;
      isa:hasProtocolApplication
              :PA3927 ;
      isa:hasStudy :S2 .

:MN1765
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.7:out:0" ;
      isa:hasMaterial :M2804 ;
      isa:hasStudy :S2 .

:D3296
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_raw_data:a_microarray.NZ_1hrs_Drug_Sample_2_Labelled_Hyb4_Scan4" ;
      dcterms:title "NZ_1hrs_Drug_Sample_2_Labelled_Hyb4_Scan4" .

:MN2210
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.79:out:0" ;
      isa:hasMaterial :M2242 ;
      isa:hasStudy :S2 .

:DPN364
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.43" ;
      isa:hasInputNode :DN1699 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:FV3604
      a       isa:FactorValue .

:DPN654
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.45" ;
      isa:hasInputNode :DN1688 ;
      isa:hasOutputNode :DN2079 ;
      isa:hasStudy :S2 .

:PA2784
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

isa:hasProperty
      a       owl:ObjectProperty ;
      rdfs:domain isa:PropertyValue ;
      rdfs:range isa:Property .

:DN2043
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.8:out:0" ;
      isa:hasData :D2657 ;
      isa:hasStudy :S2 .

:M2862
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:G-0.2-aliquot2" .

:MN1979
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.13:out:0" ;
      isa:hasMaterial :M2460 ;
      isa:hasStudy :S1 .

:FV2586
      a       isa:FactorValue .

:D2657
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3916" ;
      isa:hasFactorValue :FV2660 , :FV2659 ;
      dcterms:title "SCAN:MEXP:3916" .

:DAN619
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.8" ;
      isa:hasInputNode :MN1772 ;
      isa:hasOutputNode :DN1669 ;
      isa:hasStudy :S2 .

:MN986
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.77" ;
      isa:hasInputNode :MN1509 ;
      isa:hasOutputNode :MN1888 ;
      isa:hasProtocolApplication
              :PA3926 ;
      isa:hasStudy :S2 .

:MN1764
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.46:out:0" ;
      isa:hasMaterial :M3793 ;
      isa:hasStudy :S2 .

:PA2740
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:D3206
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC86_Sulphate_0.10_External_2_1.txt" ;
      dcterms:title "JIC86_Sulphate_0.10_External_2_1.txt" .

:MN637
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.8" ;
      isa:hasInputNode :MN1355 ;
      isa:hasOutputNode :MN2144 ;
      isa:hasProtocolApplication
              :PA3547 ;
      isa:hasStudy :S1 .

:PA3400
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

isa:hasOwner
      a       owl:AnnotationProperty ;
      rdfs:range isa:Contact .

:M3427
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.1-aliquot4" .

:DN2195
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.69:out:0" ;
      isa:hasData :D3189 ;
      isa:hasStudy :S2 .

:M2865
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:G-0.2-aliquot1" .

:PA2789
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2270
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.C-0.07-aliquot3" .

:MN1652
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.8:out:0" ;
      isa:hasMaterial :M2592 ;
      isa:hasStudy :S2 .

:MN108
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.33" ;
      isa:hasInputNode :MN2049 ;
      isa:hasOutputNode :MN1326 ;
      isa:hasProtocolApplication
              :PA2533 ;
      isa:hasStudy :S2 .

:MN981
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.50" ;
      isa:hasInputNode :MN2047 ;
      isa:hasOutputNode :MN2133 ;
      isa:hasStudy :S2 .

:DPN362
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.38" ;
      isa:hasInputNode :DN1986 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:A1230
      a       isa:Assay .

:OE3566
      a       isa:OntologyEntry .

:MN2029
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.36:out:0" ;
      isa:hasMaterial :M3766 ;
      isa:hasStudy :S2 .

:MN1763
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.53:out:0" ;
      isa:hasMaterial :M3468 ;
      isa:hasStudy :S2 .

:PA2476
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:OE3190
      a       isa:OntologyEntry .

:MN1977
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.8:out:0" ;
      isa:hasMaterial :M2385 ;
      isa:hasStudy :S2 .

:PA3406
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:OE3299
      a       isa:OntologyEntry .

:DPN126
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.1" ;
      isa:hasInputNode :DN1691 ;
      isa:hasOutputNode :DN2100 ;
      isa:hasStudy :S2 .

:MN1651
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.13:out:0" ;
      isa:hasMaterial :M2443 ;
      isa:hasStudy :S2 .

:PA2826
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:D3200
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC71_Nitrogen_0.20_External_2_1.txt" ;
      dcterms:title "JIC71_Nitrogen_0.20_External_2_1.txt" .

:MN980
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.59" ;
      isa:hasInputNode :MN1718 ;
      isa:hasOutputNode :MN1895 ;
      isa:hasStudy :S2 .

:DPN716
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.25" ;
      isa:hasInputNode :DN1591 ;
      isa:hasOutputNode :DN1327 ;
      isa:hasStudy :S2 .

:A1231
      a       isa:Assay .

:DN1676
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.5:out:0" ;
      isa:hasData :D3318 ;
      isa:hasStudy :S1 .

:MN109
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.10" ;
      isa:hasInputNode :MN1704 ;
      isa:hasOutputNode :MN2203 ;
      isa:hasProtocolApplication
              :PA2536 ;
      isa:hasStudy :S1 .

:D2651
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3915" ;
      isa:hasFactorValue :FV2654 , :FV2653 ;
      dcterms:title "SCAN:MEXP:3915" .

:MN1762
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.11:out:0" ;
      isa:hasMaterial :M3397 ;
      isa:hasStudy :S2 .

:DN1338
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.39:out:0" ;
      isa:hasData :D3378 ;
      isa:hasStudy :S2 .

:OE3564
      a       isa:OntologyEntry .

:MN1976
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.158:out:0" ;
      isa:hasMaterial :M2865 ;
      isa:hasStudy :S2 .

:FV3690
      a       isa:FactorValue .

:M3425
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.1-aliquot3" .

:MN1654
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.39:out:0" ;
      isa:hasMaterial :M3750 ;
      isa:hasStudy :S2 .

:A1232
      a       isa:Assay .

:DPN129
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.0" ;
      isa:hasInputNode :DN1756 ;
      isa:hasOutputNode :DN2078 ;
      isa:hasStudy :S2 .

:MN1541
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.103:out:0" ;
      isa:hasMaterial :M2906 ;
      isa:hasStudy :S2 .

:DPN360
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.37" ;
      isa:hasInputNode :DN1453 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DPN719
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.24" ;
      isa:hasInputNode :DN1690 ;
      isa:hasOutputNode :DN1808 ;
      isa:hasStudy :S2 .

:MN2180
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.66:out:0" ;
      isa:hasMaterial :M3183 ;
      isa:hasStudy :S2 .

:M2272
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.C-0.07-aliquot2" .

:MN983
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.74" ;
      isa:hasInputNode :MN1509 ;
      isa:hasOutputNode :MN1672 ;
      isa:hasProtocolApplication
              :PA3922 ;
      isa:hasStudy :S2 .

:MN1761
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.45:out:0" ;
      isa:hasMaterial :M2336 ;
      isa:hasStudy :S2 .

:DPN650
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.40" ;
      isa:hasInputNode :DN1324 ;
      isa:hasOutputNode :DN2037 ;
      isa:hasStudy :S2 .

:M3638
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.1-aliquot9" .

:M2866
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.G-0.2-aliquot1" .

:FV3600
      a       isa:FactorValue .

:OE3297
      a       isa:OntologyEntry .

:MN1653
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.100:out:0" ;
      isa:hasMaterial :M2575 ;
      isa:hasStudy :S2 .

:M2273
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.C-0.07-aliquot2" .

:MN1540
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.25:out:0" ;
      isa:hasMaterial :M2487 ;
      isa:hasStudy :S2 .

:MN2181
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.10:out:0" ;
      isa:hasMaterial :M2502 ;
      isa:hasStudy :S2 .

:PA3404
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:A1233
      a       isa:Assay .

:MN1760
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.64:out:0" ;
      isa:hasMaterial :M3474 ;
      isa:hasStudy :S2 .

:MN260
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.3" ;
      isa:hasInputNode :MN1575 ;
      isa:hasOutputNode :MN1568 ;
      isa:hasStudy :S2 .

:D3291
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_1hrs_Drug_Sample_1_Labelled_Hyb3_Scan3" ;
      isa:hasFactorValue :FV3293 , :FV3294 , :FV3295 ;
      dcterms:title "NZ_1hrs_Drug_Sample_1_Labelled_Hyb3_Scan3" .

:PA2479
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:MN1974
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.62:out:0" ;
      isa:hasMaterial :M2350 ;
      isa:hasStudy :S2 .

:MN982
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.70" ;
      isa:hasInputNode :MN1572 ;
      isa:hasOutputNode :MN2206 ;
      isa:hasProtocolApplication
              :PA3920 ;
      isa:hasStudy :S2 .

:OE3676
      a       isa:OntologyEntry .

:MN872
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.152" ;
      isa:hasInputNode :MN1381 ;
      isa:hasOutputNode :MN1968 ;
      isa:hasProtocolApplication
              :PA3890 ;
      isa:hasStudy :S2 .

:MN1872
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.99:out:0" ;
      isa:hasMaterial :M2945 ;
      isa:hasStudy :S2 .

:DAN611
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.2" ;
      isa:hasInputNode :MN1332 ;
      isa:hasOutputNode :DN1816 ;
      isa:hasStudy :S2 .

:PA2936
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1102 .

:DAN814
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.102" ;
      isa:hasInputNode :MN2086 ;
      isa:hasOutputNode :DN2039 ;
      isa:hasStudy :S2 .

:PA2693
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DPN659
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.38" ;
      isa:hasInputNode :DN1705 ;
      isa:hasOutputNode :DN1791 ;
      isa:hasStudy :S2 .

:M2756
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3946" .

:M2869
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.E-0.07-aliquot1" .

:OE3130
      a       isa:OntologyEntry .

:DPN932
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.103" ;
      isa:hasInputNode :DN1524 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:M2542
      a       isa:Material ;
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      a       isa:ProtocolApplication ;
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      a       isa:FactorValue .

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      a       isa:OntologyEntry .

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              :PA3928 ;
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      a       isa:ProtocolApplication ;
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      a       isa:ProtocolApplication ;
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      a       isa:ProtocolApplication ;
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      a       isa:Material ;
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      a       isa:DataNode ;
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:M3265
      a       isa:Material ;
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      a       isa:Material ;
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      a       isa:ProtocolApplication ;
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:PA2678
      a       isa:ProtocolApplication ;
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      a       isa:Data ;
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      a       isa:OntologyEntry .

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      a       isa:Material ;
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:M3180
      a       isa:Material ;
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      a       isa:Material ;
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      a       isa:Material ;
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      a       isa:ProtocolApplication ;
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:A1170
      a       isa:Assay .

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:PA2715
      a       isa:ProtocolApplication ;
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      a       isa:Material ;
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:PA3713
      a       isa:ProtocolApplication ;
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      a       isa:MaterialNode ;
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      a       isa:MaterialNode ;
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:OE3105
      a       isa:OntologyEntry .

:A1171
      a       isa:Assay .

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      a       isa:MaterialNode ;
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:M3785
      a       isa:Material ;
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:M2305
      a       isa:Material ;
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      a       isa:MaterialNode ;
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:FV3280
      a       isa:FactorValue .

:DAN476
      a       isa:DataAcquisition ;
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:OE3610
      a       isa:OntologyEntry .

:M3819
      a       isa:Material ;
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:OE3824
      a       isa:OntologyEntry .

:MN1398
      a       isa:MaterialNode ;
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      a       isa:MaterialNode ;
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:MN700
      a       isa:MaterialProcessing ;
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              :PA3674 ;
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:D3149
      a       isa:Data ;
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:A1172
      a       isa:Assay .

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      a       isa:FactorValue .

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      a       isa:FactorValue .

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      a       isa:OntologyEntry .

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      a       isa:Assay .

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      a       isa:Data ;
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              :PA3684 ;
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              :PA2289 ;
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      a       isa:OntologyEntry .

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      a       isa:Assay .

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      a       isa:MaterialProcessing ;
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              :PA3679 ;
      isa:hasStudy :S2 .

:A1287
      a       isa:Assay .

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      a       isa:MaterialNode ;
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      a       isa:MaterialNode ;
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      a       isa:MaterialNode ;
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      a       isa:DataNode ;
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      a       isa:Material ;
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:PA2719
      a       isa:ProtocolApplication ;
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:M3183
      a       isa:Material ;
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:OE3100
      a       isa:OntologyEntry .

:M2248
      a       isa:Material ;
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      a       isa:MaterialNode ;
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      a       isa:Material ;
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:M3788
      a       isa:Material ;
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:MN25
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1554 ;
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              :PA2286 ;
      isa:hasStudy :S2 .

:MN2143
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:A1175
      a       isa:Assay .

:MN1465
      a       isa:MaterialNode ;
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      isa:hasMaterial :M3945 ;
      isa:hasStudy :S2 .

:MN29
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1833 ;
      isa:hasProtocolApplication
              :PA2298 ;
      isa:hasStudy :S2 .

:D2878
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_raw_data:a_microarray.NZ_4hrs_Vehicle_Sample_2_Labelled_Hyb14_Scan14" ;
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:FV3727
      a       isa:FactorValue .

:D3144
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC64_Nitrogen_0.07_External_1_1.txt" ;
      dcterms:title "JIC64_Nitrogen_0.07_External_1_1.txt" .

:PA2676
      a       isa:ProtocolApplication ;
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:DN2159
      a       isa:DataNode ;
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      isa:hasData :D2882 ;
      isa:hasStudy :S1 .

:DN1539
      a       isa:DataNode ;
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      isa:hasData :D3687 ;
      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1576 ;
      isa:hasProtocolApplication
              :PA2610 ;
      isa:hasStudy :S2 .

:A1288
      a       isa:Assay .

:M3077
      a       isa:Material ;
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:D2701
      a       isa:Data ;
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:M2309
      a       isa:Material ;
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:FV3596
      a       isa:FactorValue .

:M3789
      a       isa:Material ;
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:M2501
      a       isa:Material ;
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:MN28
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN2060 ;
      isa:hasProtocolApplication
              :PA2295 ;
      isa:hasStudy :S2 .

:PA2963
      a       isa:ProtocolApplication ;
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:MN706
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN2176 ;
      isa:hasOutputNode :MN2070 ;
      isa:hasStudy :S2 .

:D3652
      a       isa:Data ;
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      isa:hasFactorValue :FV3655 , :FV3654 ;
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:MN2142
      a       isa:MaterialNode ;
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:A1176
      a       isa:Assay .

:MN1313
      a       isa:MaterialNode ;
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:FV3728
      a       isa:FactorValue .

:MN1466
      a       isa:MaterialNode ;
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:MN132
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1933 ;
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              :PA2607 ;
      isa:hasStudy :S2 .

:DPN438
      a       isa:DataProcessing ;
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      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

isa:DataAcquisition
      rdfs:subClassOf isa:Processing .

:A1289
      a       isa:Assay .

:MN1394
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2401 ;
      isa:hasStudy :S1 .

:FV3595
      a       isa:FactorValue .

:MN27
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1982 ;
      isa:hasOutputNode :MN1659 ;
      isa:hasProtocolApplication
              :PA2292 ;
      isa:hasStudy :S2 .

:M2502
      a       isa:Material ;
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:M2246
      a       isa:Material ;
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:MN1528
      a       isa:MaterialNode ;
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:M2245
      a       isa:Material ;
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:M2507
      a       isa:Material ;
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:MN1745
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:DAN538
      a       isa:DataAcquisition ;
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      isa:hasOutputNode :DN1372 ;
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:MN2036
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:DPN435
      a       isa:DataProcessing ;
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      isa:hasOutputNode :DN1379 ;
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:MN2201
      a       isa:MaterialNode ;
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:M3188
      a       isa:Material ;
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:DPN321
      a       isa:DataProcessing ;
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      isa:hasStudy :S2 .

:MN244
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1436 ;
      isa:hasOutputNode :MN2038 ;
      isa:hasProtocolApplication
              :PA2875 ;
      isa:hasStudy :S2 .

:A1282
      a       isa:Assay .

:M2939
      a       isa:Material ;
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:D2989
      a       isa:Data ;
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:MN2141
      a       isa:MaterialNode ;
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:MN139
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1429 ;
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              :PA2635 ;
      isa:hasStudy :S2 .

:A1177
      a       isa:Assay .

:M2508
      a       isa:Material ;
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:M2937
      a       isa:Material ;
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:OE3066
      a       isa:OntologyEntry .

:PA3825
      a       isa:ProtocolApplication ;
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:DAN537
      a       isa:DataAcquisition ;
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      isa:hasStudy :S2 .

:M3409
      a       isa:Material ;
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:MN1746
      a       isa:MaterialNode ;
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:MN2202
      a       isa:MaterialNode ;
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:A1178
      a       isa:Assay .

:DAN536
      a       isa:DataAcquisition ;
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:MN243
      a       isa:MaterialProcessing ;
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              :PA2872 ;
      isa:hasStudy :S2 .

:PA2566
      a       isa:ProtocolApplication ;
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:A1283
      a       isa:Assay .

:PA2235
      a       isa:ProtocolApplication ;
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:M2505
      a       isa:Material ;
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:M3632
      a       isa:Material ;
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:M2243
      a       isa:Material ;
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:OE3069
      a       isa:OntologyEntry .

:FV3592
      a       isa:FactorValue .

:MN1747
      a       isa:MaterialNode ;
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:MN242
      a       isa:MaterialProcessing ;
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              :PA2870 ;
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:MN931
      a       isa:MaterialProcessing ;
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:MN1391
      a       isa:MaterialNode ;
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:MN2034
      a       isa:MaterialNode ;
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:DN1838
      a       isa:DataNode ;
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      isa:hasStudy :S2 .

:MN137
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1794 ;
      isa:hasOutputNode :MN1468 ;
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              :PA2626 ;
      isa:hasStudy :S2 .

:MN1469
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2356 ;
      isa:hasStudy :S1 .

:D2986
      a       isa:Data ;
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:M2242
      a       isa:Material ;
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:PA2960
      a       isa:ProtocolApplication ;
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:FV3591
      a       isa:FactorValue .

:M3072
      a       isa:Material ;
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:DAN539
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN1684 ;
      isa:hasOutputNode :DN1918 ;
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:MN241
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1464 ;
      isa:hasProtocolApplication
              :PA2867 ;
      isa:hasStudy :S2 .

:MN2200
      a       isa:MaterialNode ;
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:A1285
      a       isa:Assay .

:MN2033
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:MN136
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1573 ;
      isa:hasOutputNode :MN1388 ;
      isa:hasProtocolApplication
              :PA2624 ;
      isa:hasStudy :S2 .

:MN1749
      a       isa:MaterialNode ;
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:PA2607
      a       isa:ProtocolApplication ;
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:D3725
      a       isa:Data ;
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:D3311
      a       isa:Data ;
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:OE3827
      a       isa:OntologyEntry .

:PA2459
      a       isa:ProtocolApplication ;
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:MN240
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              :PA2864 ;
      isa:hasStudy :S2 .

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      isa:hasData :D2705 ;
      isa:hasStudy :S2 .

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      isa:hasOutputNode :DN1379 ;
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      a       isa:ProtocolApplication ;
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      a       isa:Material ;
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isa:hasAccessionID
      a       owl:FunctionalProperty , owl:DatatypeProperty ;
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      a       isa:Material ;
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      a       isa:OntologyEntry .

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      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1417 ;
      isa:hasOutputNode :MN1549 ;
      isa:hasStudy :S2 .

:M2477
      a       isa:Material ;
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:PA2232
      a       isa:ProtocolApplication ;
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:A1280
      a       isa:Assay .

:DN1834
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.40:out:0" ;
      isa:hasData :D3146 ;
      isa:hasStudy :S2 .

:DPN327
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      isa:hasInputNode :DN1673 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN2203
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.10:out:0" ;
      isa:hasMaterial :M2537 ;
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:MN2038
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2877 ;
      isa:hasStudy :S2 .

:M3407
      a       isa:Material ;
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isa:Processing
      rdfs:subClassOf isa:GraphElement .

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      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN2189 ;
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:M3496
      a       isa:Material ;
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:A1281
      a       isa:Assay .

:DN1980
      a       isa:DataNode ;
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      isa:hasData :D3370 ;
      isa:hasStudy :S2 .

:PA2456
      a       isa:ProtocolApplication ;
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:D3044
      a       isa:Data ;
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:MN590
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1894 ;
      isa:hasOutputNode :MN2177 ;
      isa:hasProtocolApplication
              :PA3461 ;
      isa:hasStudy :S2 .

:DAN540
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN1414 ;
      isa:hasOutputNode :DN2161 ;
      isa:hasStudy :S2 .

:MN1963
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.127:out:0" ;
      isa:hasMaterial :M3873 ;
      isa:hasStudy :S2 .

:D3034
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC48_GlucoseO2_0.07_Internal_3_1.txt" ;
      dcterms:title "JIC48_GlucoseO2_0.07_Internal_3_1.txt" .

:M3494
      a       isa:Material ;
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:DN1323
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.12:out:0" ;
      isa:hasData :D2890 ;
      isa:hasStudy :S2 .

:M2726
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3932" .

isa:PropertyValue
      rdfs:subClassOf isa:FreeTextTerm .

:M3413
      a       isa:Material ;
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:OE3552
      a       isa:OntologyEntry .

:MN925
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1792 ;
      isa:hasOutputNode :MN1951 ;
      isa:hasStudy :S2 .

:M3627
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:source:culture3" .

:MN1962
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.29:out:0" ;
      isa:hasMaterial :M2478 ;
      isa:hasStudy :S2 .

:MN591
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN2063 ;
      isa:hasProtocolApplication
              :PA3463 ;
      isa:hasStudy :S2 .

:A1306
      a       isa:Assay .

:PA2467
      a       isa:ProtocolApplication ;
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:MN1689
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.1:out:0" ;
      isa:hasMaterial :M2392 ;
      isa:hasStudy :S1 .

:OE3329
      a       isa:OntologyEntry .

:PA2812
      a       isa:ProtocolApplication ;
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:DN1324
      a       isa:DataNode ;
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      isa:hasData :D3368 ;
      isa:hasStudy :S2 .

isa:hasAssayFields
      a       owl:DatatypeProperty ;
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:FV3612
      a       isa:FactorValue .

:OE3285
      a       isa:OntologyEntry .

:PA2752
      a       isa:ProtocolApplication ;
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:DN2051
      a       isa:DataNode ;
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      isa:hasData :D3539 ;
      isa:hasStudy :S2 .

:OE2583
      a       isa:OntologyEntry .

:M2664
      a       isa:Material ;
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:MN1813
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2704 ;
      isa:hasStudy :S2 .

:FV2617
      a       isa:FactorValue .

:DN2055
      a       isa:DataNode ;
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      isa:hasData :D3525 ;
      isa:hasStudy :S2 .

:MN1751
      a       isa:MaterialNode ;
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      isa:hasMaterial :M3141 ;
      isa:hasStudy :S2 .

:DN1984
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.90:out:0" ;
      isa:hasData :D3042 ;
      isa:hasStudy :S2 .

:A1303
      a       isa:Assay .

:M3492
      a       isa:Material ;
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:DN1325
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.3:out:0" ;
      isa:hasData :D2603 ;
      isa:hasStudy :S2 .

:D3036
      a       isa:Data ;
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:PA2572
      a       isa:ProtocolApplication ;
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:M2724
      a       isa:Material ;
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:M2877
      a       isa:Material ;
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:M2931
      a       isa:Material ;
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:FV3611
      a       isa:FactorValue .

:MN927
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1549 ;
      isa:hasOutputNode :MN1855 ;
      isa:hasStudy :S2 .

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      a       isa:Material ;
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:MN1966
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2370 ;
      isa:hasStudy :S2 .

:DN2054
      a       isa:DataNode ;
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      isa:hasData :D3052 ;
      isa:hasStudy :S2 .

:A1304
      a       isa:Assay .

:PA3471
      a       isa:ProtocolApplication ;
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:FV2616
      a       isa:FactorValue .

:MN1750
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2246 ;
      isa:hasStudy :S2 .

:PA2465
      a       isa:ProtocolApplication ;
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:OE2698
      a       isa:OntologyEntry .

:MN1810
      a       isa:MaterialNode ;
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      isa:hasMaterial :M3910 ;
      isa:hasStudy :S2 .

:MN1687
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.28:out:0" ;
      isa:hasMaterial :M2231 ;
      isa:hasStudy :S2 .

:DN1688
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.45:out:0" ;
      isa:hasData :D3364 ;
      isa:hasStudy :S2 .

:M2876
      a       isa:Material ;
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:OE2585
      a       isa:OntologyEntry .

:M2662
      a       isa:Material ;
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:MN1965
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.23:out:0" ;
      isa:hasMaterial :M2492 ;
      isa:hasStudy :S2 .

:DN1472
      a       isa:DataNode ;
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      isa:hasData :D3065 ;
      isa:hasStudy :S2 .

:DN1986
      a       isa:DataNode ;
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      isa:hasData :D3119 ;
      isa:hasStudy :S2 .

:PA2817
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M3490
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:S-0.2-aliquot3" .

:PA2462
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:MN594
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.26" ;
      isa:hasInputNode :MN1428 ;
      isa:hasOutputNode :MN1949 ;
      isa:hasProtocolApplication
              :PA3469 ;
      isa:hasStudy :S2 .

:PA2574
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN929
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1929 ;
      isa:hasOutputNode :MN1754 ;
      isa:hasStudy :S2 .

:M2696
      a       isa:Material ;
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:MN1968
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.152:out:0" ;
      isa:hasMaterial :M2839 ;
      isa:hasStudy :S2 .

:A1309
      a       isa:Assay .

:DN1829
      a       isa:DataNode ;
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      isa:hasData :D3001 ;
      isa:hasStudy :S2 .

:D3318
      a       isa:Data ;
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:M2933
      a       isa:Material ;
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:RS1097
      a       isa:ReferenceSources ;
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      dcterms:description "Unit Ontology" ;
      dcterms:hasVersion "v 1.26" ;
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:DN1320
      a       isa:DataNode ;
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      isa:hasData :D3044 ;
      isa:hasStudy :S2 .

:PA2226
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:D2645
      a       isa:Data ;
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      isa:hasFactorValue :FV2648 , :FV2647 ;
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:MN595
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1708 ;
      isa:hasOutputNode :MN1481 ;
      isa:hasProtocolApplication
              :PA3471 ;
      isa:hasStudy :S2 .

:MN1752
      a       isa:MaterialNode ;
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      isa:hasMaterial :M3870 ;
      isa:hasStudy :S2 .

:PA3473
      a       isa:ProtocolApplication ;
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:PA3828
      a       isa:ProtocolApplication ;
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:M2874
      a       isa:Material ;
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:MN1967
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:RS1096
      a       isa:ReferenceSources ;
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      dcterms:description "Phenotypic qualities (properties)" ;
      dcterms:hasVersion "v 1.26" ;
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:PA2819
      a       isa:ProtocolApplication ;
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:DN1474
      a       isa:DataNode ;
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      isa:hasData :D3343 ;
      isa:hasStudy :S1 .

:D3316
      a       isa:Data ;
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:DN1602
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.21:out:0" ;
      isa:hasData :D3615 ;
      isa:hasStudy :S2 .

:MN592
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1960 ;
      isa:hasOutputNode :MN1516 ;
      isa:hasProtocolApplication
              :PA3465 ;
      isa:hasStudy :S2 .

:MN868
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1734 ;
      isa:hasProtocolApplication
              :PA3887 ;
      isa:hasStudy :S2 .

:MN1755
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2803 ;
      isa:hasStudy :S2 .

:M3625
      a       isa:Material ;
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:M2694
      a       isa:Material ;
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:MN869
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1603 ;
      isa:hasOutputNode :MN1780 ;
      isa:hasStudy :S2 .

:M2873
      a       isa:Material ;
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:M3411
      a       isa:Material ;
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:DAN841
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN1378 ;
      isa:hasOutputNode :DN2165 ;
      isa:hasStudy :S2 .

:M2935
      a       isa:Material ;
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:PA2229
      a       isa:ProtocolApplication ;
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:M2728
      a       isa:Material ;
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:OE3327
      a       isa:OntologyEntry .

:D3039
      a       isa:Data ;
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:OE2619
      a       isa:OntologyEntry .

:PA3475
      a       isa:ProtocolApplication ;
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:DN1987
      a       isa:DataNode ;
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      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.47:out:0" ;
      isa:hasData :D3531 ;
      isa:hasStudy :S2 .

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      a       isa:MaterialNode ;
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      isa:hasMaterial :M3072 ;
      isa:hasStudy :S2 .

:MN593
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1763 ;
      isa:hasOutputNode :MN1789 ;
      isa:hasProtocolApplication
              :PA3467 ;
      isa:hasStudy :S2 .

:D2643
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3914" ;
      dcterms:title "SCAN:MEXP:3914" .

:MN867
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.75" ;
      isa:hasInputNode :MN1603 ;
      isa:hasOutputNode :MN1993 ;
      isa:hasStudy :S2 .

:MN1969
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:A1308
      a       isa:Assay .

:MN21
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.47" ;
      isa:hasInputNode :MN2011 ;
      isa:hasOutputNode :MN1617 ;
      isa:hasProtocolApplication
              :PA2274 ;
      isa:hasStudy :S2 .

:FV3287
      a       isa:FactorValue .

:M2692
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:G-0.2-aliquot4" .

:MN866
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.156" ;
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      isa:hasOutputNode :MN2127 ;
      isa:hasProtocolApplication
              :PA3885 ;
      isa:hasStudy :S2 .

:DAN601
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN1795 ;
      isa:hasOutputNode :DN1439 ;
      isa:hasStudy :S2 .

:M3205
      a       isa:Material ;
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:DAN310
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.86" ;
      isa:hasInputNode :MN1713 ;
      isa:hasOutputNode :DN2084 ;
      isa:hasStudy :S2 .

:PA2759
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN598
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1578 ;
      isa:hasOutputNode :MN1502 ;
      isa:hasProtocolApplication
              :PA3477 ;
      isa:hasStudy :S2 .

:DN1476
      a       isa:DataNode ;
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      isa:hasData :D3366 ;
      isa:hasStudy :S2 .

:MN1682
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:MN1537
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:MN22
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.46" ;
      isa:hasInputNode :MN1903 ;
      isa:hasOutputNode :MN1626 ;
      isa:hasProtocolApplication
              :PA2277 ;
      isa:hasStudy :S2 .

:PA3719
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

isa:Characteristic
      rdfs:subClassOf isa:Property .

:D2649
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3915" ;
      dcterms:title "SCAN:MEXP:3915" .

:FV3286
      a       isa:FactorValue .

:MN865
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.78" ;
      isa:hasInputNode :MN2122 ;
      isa:hasOutputNode :MN1551 ;
      isa:hasStudy :S2 .

:MN1681
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.70:out:0" ;
      isa:hasMaterial :M3151 ;
      isa:hasStudy :S2 .

:OE2613
      a       isa:OntologyEntry .

:DN2165
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.110:out:0" ;
      isa:hasData :D3868 ;
      isa:hasStudy :S2 .

:PA2682
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:PA3477
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:DN1989
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.12:out:0" ;
      isa:hasData :D3548 ;
      isa:hasStudy :S2 .

:MN599
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.27" ;
      isa:hasInputNode :MN1625 ;
      isa:hasOutputNode :MN1919 ;
      isa:hasProtocolApplication
              :PA3479 ;
      isa:hasStudy :S2 .

:MN1536
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.10:out:0" ;
      isa:hasMaterial :M2433 ;
      isa:hasStudy :S2 .

:MN23
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.45" ;
      isa:hasInputNode :MN1745 ;
      isa:hasOutputNode :MN1679 ;
      isa:hasProtocolApplication
              :PA2280 ;
      isa:hasStudy :S2 .

:MN1818
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.108:out:0" ;
      isa:hasMaterial :M3498 ;
      isa:hasStudy :S2 .

:DN2168
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.19:out:0" ;
      isa:hasData :D3659 ;
      isa:hasStudy :S2 .

:MN864
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.159" ;
      isa:hasInputNode :MN1411 ;
      isa:hasOutputNode :MN1788 ;
      isa:hasProtocolApplication
              :PA3883 ;
      isa:hasStudy :S2 .

:MN596
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.24" ;
      isa:hasInputNode :MN1760 ;
      isa:hasOutputNode :MN1478 ;
      isa:hasProtocolApplication
              :PA3473 ;
      isa:hasStudy :S2 .

:MN1680
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.138:out:0" ;
      isa:hasMaterial :M2955 ;
      isa:hasStudy :S2 .

:OE3606
      a       isa:OntologyEntry .

:DN2216
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.77:out:0" ;
      isa:hasData :D3039 ;
      isa:hasStudy :S2 .

:DAN312
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.87" ;
      isa:hasInputNode :MN2088 ;
      isa:hasOutputNode :DN1507 ;
      isa:hasStudy :S2 .

:MN1535
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.20:out:0" ;
      isa:hasMaterial :M3714 ;
      isa:hasStudy :S2 .

:MN24
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.7" ;
      isa:hasInputNode :MN1600 ;
      isa:hasOutputNode :MN1547 ;
      isa:hasProtocolApplication
              :PA2283 ;
      isa:hasStudy :S2 .

:MN1819
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.44:out:0" ;
      isa:hasMaterial :M2687 ;
      isa:hasStudy :S2 .

:FV3723
      a       isa:FactorValue .

:FV3288
      a       isa:FactorValue .

:MN863
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.77" ;
      isa:hasInputNode :MN1743 ;
      isa:hasOutputNode :MN1849 ;
      isa:hasStudy :S2 .

:PA2684
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:M3202
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC64_Nitrogen_0.07_External_1_3" .

:OE2615
      a       isa:OntologyEntry .

:D3152
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC60_Carbon_0.10_External_3_1.txt" ;
      dcterms:title "JIC60_Carbon_0.10_External_3_1.txt" .

:M2691
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:source:culture18" .

:PA2352
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN597
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.23" ;
      isa:hasInputNode :MN1329 ;
      isa:hasOutputNode :MN1965 ;
      isa:hasProtocolApplication
              :PA3475 ;
      isa:hasStudy :S2 .

:DN1479
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.37:out:0" ;
      isa:hasData :D3374 ;
      isa:hasStudy :S2 .

:PA3479
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:DN2217
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.14:out:0" ;
      isa:hasData :D2991 ;
      isa:hasStudy :S2 .

:MN1534
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.24:out:0" ;
      isa:hasMaterial :M3698 ;
      isa:hasStudy :S2 .

:D3804
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3919" ;
      isa:hasFactorValue :FV3807 , :FV3806 ;
      dcterms:title "SCAN:MEXP:3919" .

:DN2161
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.36:out:0" ;
      isa:hasData :D3386 ;
      isa:hasStudy :S2 .

:FV3722
      a       isa:FactorValue .

:DPN794
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.10" ;
      isa:hasInputNode :DN1439 ;
      isa:hasOutputNode :DN1910 ;
      isa:hasStudy :S2 .

:PA2755
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:M2312
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.N-0.2-aliquot8" .

:M2722
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3928" .

:MN1533
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.89:out:0" ;
      isa:hasMaterial :M3084 ;
      isa:hasStudy :S2 .

:DAN314
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.84" ;
      isa:hasInputNode :MN1805 ;
      isa:hasOutputNode :DN1525 ;
      isa:hasStudy :S2 .

:DPN649
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.41" ;
      isa:hasInputNode :DN1476 ;
      isa:hasOutputNode :DN1511 ;
      isa:hasStudy :S2 .

:MN1686
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.29:out:0" ;
      isa:hasMaterial :M2741 ;
      isa:hasStudy :S2 .

:DN2218
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.22:out:0" ;
      isa:hasData :D3036 ;
      isa:hasStudy :S2 .

:DN1530
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.11:out:0" ;
      isa:hasData :D2970 ;
      isa:hasStudy :S2 .

:A1301
      a       isa:Assay .

:PA2711
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN862
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.158" ;
      isa:hasInputNode :MN1411 ;
      isa:hasOutputNode :MN1976 ;
      isa:hasProtocolApplication
              :PA3881 ;
      isa:hasStudy :S2 .

:MN1460
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.15:out:0" ;
      isa:hasMaterial :M3632 ;
      isa:hasStudy :S2 .

:M2311
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.2-aliquot8" .

:M3208
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC64_Nitrogen_0.07_External_1_1" .

:DAN691
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.17" ;
      isa:hasInputNode :MN1322 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:M2394
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:labelled_extract:a_microarray.NZ_2hrs_Vehicle_Sample_1_Labelled" .

:MN1685
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.14:out:0" ;
      isa:hasMaterial :M2445 ;
      isa:hasStudy :S2 .

:A1302
      a       isa:Assay .

:PA2358
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1108 .

:MN861
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.70" ;
      isa:hasInputNode :MN2075 ;
      isa:hasOutputNode :MN1681 ;
      isa:hasStudy :S2 .

:OE3555
      a       isa:OntologyEntry .

:PA2713
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN1814
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.17:out:0" ;
      isa:hasMaterial :M3439 ;
      isa:hasStudy :S2 .

:M2720
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3929" .

:DN2163
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.95:out:0" ;
      isa:hasData :D3047 ;
      isa:hasStudy :S2 .

:M2314
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.2-aliquot9" .

:MN1684
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.35:out:0" ;
      isa:hasMaterial :M2777 ;
      isa:hasStudy :S2 .

:M2391
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:labelled_extract:a_microarray.NZ_1hrs_Drug_Sample_1_Labelled" .

:PA2757
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN860
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.73" ;
      isa:hasInputNode :MN1943 ;
      isa:hasOutputNode :MN1629 ;
      isa:hasStudy :S2 .

:DAN316
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.85" ;
      isa:hasInputNode :MN1731 ;
      isa:hasOutputNode :DN1580 ;
      isa:hasStudy :S2 .

:DN1532
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.55:out:0" ;
      isa:hasData :D3142 ;
      isa:hasStudy :S2 .

:OE3602
      a       isa:OntologyEntry .

:OE3558
      a       isa:OntologyEntry .

:PA2355
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1108 .

:MN20
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.1" ;
      isa:hasInputNode :MN1733 ;
      isa:hasOutputNode :MN1605 ;
      isa:hasProtocolApplication
              :PA2271 ;
      isa:hasStudy :S2 .

:MN1815
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.48:out:0" ;
      isa:hasMaterial :M2344 ;
      isa:hasStudy :S2 .

:OE3283
      a       isa:OntologyEntry .

:DAN318
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.82" ;
      isa:hasInputNode :MN1880 ;
      isa:hasOutputNode :DN1812 ;
      isa:hasStudy :S2 .

:D3659
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3924" ;
      isa:hasFactorValue :FV3661 , :FV3662 ;
      dcterms:title "SCAN:MEXP:3924" .

:MN1683
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.136:out:0" ;
      isa:hasMaterial :M2978 ;
      isa:hasStudy :S2 .

:M2392
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:hybridization:a_microarray.NZ_1hrs_Drug_Sample_1_Labelled_Hyb3" .

:DN1531
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.5:out:0" ;
      isa:hasData :D2620 ;
      isa:hasStudy :S2 .

:PA2680
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:DN2100
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.1:out:0" ;
      isa:hasData :D2584 ;
      isa:hasStudy :S2 .

:A1300
      a       isa:Assay .

:MN1387
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.52:out:0" ;
      isa:hasMaterial :M3819 ;
      isa:hasStudy :S2 .

:MN238
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.11" ;
      isa:hasInputNode :MN1729 ;
      isa:hasOutputNode :MN1341 ;
      isa:hasProtocolApplication
              :PA2859 ;
      isa:hasStudy :S2 .

:A1183
      a       isa:Assay .

:MN651
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.0" ;
      isa:hasInputNode :MN1458 ;
      isa:hasOutputNode :MN1988 ;
      isa:hasProtocolApplication
              :PA3573 ;
      isa:hasStudy :S1 .

:DAN463
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.46" ;
      isa:hasInputNode :MN1661 ;
      isa:hasOutputNode :DN1592 ;
      isa:hasStudy :S2 .

:M3101
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC8_Carbon_0.20_Internal_2_1" .

:M2461
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:hybridization:a_microarray.NZ_4hrs_Vehicle_Sample_2_Labelled_Hyb14" .

:FV3350
      a       isa:FactorValue .

:M2317
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.1-aliquot9" .

:MN97
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.10" ;
      isa:hasInputNode :MN1608 ;
      isa:hasOutputNode :MN2181 ;
      isa:hasProtocolApplication
              :PA2500 ;
      isa:hasStudy :S2 .

:MN1519
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.34:out:0" ;
      isa:hasMaterial :M2324 ;
      isa:hasStudy :S2 .

:D3735
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3942" ;
      isa:hasFactorValue :FV3738 , :FV3737 ;
      dcterms:title "SCAN:MEXP:3942" .

:D2991
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC23_Phosphate_0.10_Internal_2_1.txt" ;
      dcterms:title "JIC23_Phosphate_0.10_Internal_2_1.txt" .

:OE3118
      a       isa:OntologyEntry .

:MN1386
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.21:out:0" ;
      isa:hasMaterial :M3405 ;
      isa:hasStudy :S2 .

:MN712
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.15" ;
      isa:hasInputNode :MN1339 ;
      isa:hasOutputNode :MN1837 ;
      isa:hasProtocolApplication
              :PA3692 ;
      isa:hasStudy :S2 .

:A1184
      a       isa:Assay .

:MN652
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.1" ;
      isa:hasInputNode :MN1321 ;
      isa:hasOutputNode :MN2209 ;
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              :PA3574 ;
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:RS1098
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      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.64:out:0" ;
      isa:hasData :D3107 ;
      isa:hasStudy :S2 .

:M2687
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3951" .

:D3309
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_raw_data:a_microarray.NZ_1hrs_Vehicle_Sample_1_Labelled_Hyb5_Scan5" ;
      dcterms:title "NZ_1hrs_Vehicle_Sample_1_Labelled_Hyb5_Scan5" .

:M2888
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.1-aliquot6" .

:M2735
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.07-aliquot5" .

:PA3699
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DPN918
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.106" ;
      isa:hasInputNode :DN2020 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DN1699
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.43:out:0" ;
      isa:hasData :D3124 ;
      isa:hasStudy :S2 .

:DPN452
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.73" ;
      isa:hasInputNode :DN2185 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:M3482
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.1-aliquot1" .

:PA2801
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN912
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.98" ;
      isa:hasInputNode :MN2038 ;
      isa:hasOutputNode :MN1874 ;
      isa:hasStudy :S2 .

:MN1951
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.91:out:0" ;
      isa:hasMaterial :M3064 ;
      isa:hasStudy :S2 .

isa:Contact
      rdfs:subClassOf isa:Annotatable .

:OE3540
      a       isa:OntologyEntry .

:OE2596
      a       isa:OntologyEntry .

:MN913
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.95" ;
      isa:hasInputNode :MN1464 ;
      isa:hasOutputNode :MN1361 ;
      isa:hasStudy :S2 .

:M3393
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.07-aliquot1" .

:M2677
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3952" .

:MN1800
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.45:out:0" ;
      isa:hasMaterial :M3251 ;
      isa:hasStudy :S2 .

:M2738
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.2-aliquot10" .

:MN1679
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.45:out:0" ;
      isa:hasMaterial :M2282 ;
      isa:hasStudy :S2 .

:PA2763
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:M3401
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.07-aliquot4" .

:MN1677
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.72:out:0" ;
      isa:hasMaterial :M2513 ;
      isa:hasStudy :S2 .

:DN1698
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.13:out:0" ;
      isa:hasData :D3628 ;
      isa:hasStudy :S2 .

:DPN919
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.107" ;
      isa:hasInputNode :DN1897 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DN1312
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.7:out:0" ;
      isa:hasData :D3206 ;
      isa:hasStudy :S2 .

:PA3481
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN1950
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.11:out:0" ;
      isa:hasMaterial :M2436 ;
      isa:hasStudy :S2 .

:MN1801
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.107:out:0" ;
      isa:hasMaterial :M2913 ;
      isa:hasStudy :S2 .

:MN914
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.96" ;
      isa:hasInputNode :MN1464 ;
      isa:hasOutputNode :MN1361 ;
      isa:hasStudy :S2 .

:FV3624
      a       isa:FactorValue .

:D2880
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_raw_data:a_microarray.NZ_2hrs_Vehicle_Sample_2_Labelled_Hyb10_Scan10" ;
      dcterms:title "NZ_2hrs_Vehicle_Sample_2_Labelled_Hyb10_Scan10" .

:M2689
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3949" .

:M3324
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC75_Phosphate_0.07_External_3_1" .

:MN580
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.99" ;
      isa:hasInputNode :MN1954 ;
      isa:hasOutputNode :MN1872 ;
      isa:hasStudy :S2 .

:M3211
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC18_Nitrogen_0.20_Internal_3_1" .

:DAN534
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.37" ;
      isa:hasInputNode :MN1385 ;
      isa:hasOutputNode :DN1479 ;
      isa:hasStudy :S2 .

:MN1743
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.77:out:0" ;
      isa:hasMaterial :M3882 ;
      isa:hasStudy :S2 .

:DAN320
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.83" ;
      isa:hasInputNode :MN1408 ;
      isa:hasOutputNode :DN1724 ;
      isa:hasStudy :S2 .

:M2807
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_proteome.Pool1" .

:DPN342
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.28" ;
      isa:hasInputNode :DN2067 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:M2923
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:extract:a_microarray.NZ_0hrs_Sample_1_Extract" .

:PA2761
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:M2806
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_proteome.JC_C-0.2" .

:OE3278
      a       isa:OntologyEntry .

:M3395
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.1-aliquot3" .

:MN1958
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.71:out:0" ;
      isa:hasMaterial :M2498 ;
      isa:hasStudy :S2 .

:OE2594
      a       isa:OntologyEntry .

:M2671
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:S-0.2-aliquot5" .

:MN581
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.31" ;
      isa:hasInputNode :MN1888 ;
      isa:hasOutputNode :MN1853 ;
      isa:hasProtocolApplication
              :PA3443 ;
      isa:hasStudy :S2 .

:PA2563
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:M3323
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC74_Phosphate_0.07_External_2_1" .

:DAN535
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.38" ;
      isa:hasInputNode :MN1315 ;
      isa:hasOutputNode :DN1705 ;
      isa:hasStudy :S2 .

:D2631
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3912" ;
      isa:hasFactorValue :FV2634 , :FV2633 ;
      dcterms:title "SCAN:MEXP:3912" .

:MN1742
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.91:out:0" ;
      isa:hasMaterial :M2233 ;
      isa:hasStudy :S2 .

:M2808
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_proteome.8761" .

:D3386
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3944" ;
      dcterms:title "SCAN:MEXP:3944" .

:D3305
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_0hrs_Sample_2_Labelled_Hyb2_Scan2" ;
      isa:hasFactorValue :FV3307 , :FV3308 ;
      dcterms:title "NZ_0hrs_Sample_2_Labelled_Hyb2_Scan2" .

:DPN917
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.105" ;
      isa:hasInputNode :DN1990 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:PA3487
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:DN1975
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.13:out:0" ;
      isa:hasData :D2986 ;
      isa:hasStudy :S2 .

:OE3339
      a       isa:OntologyEntry .

:DPN789
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.11" ;
      isa:hasInputNode :DN1900 ;
      isa:hasOutputNode :DN1826 ;
      isa:hasStudy :S2 .

:M2739
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.C-0.2-aliquot10" .

:M2683
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3950" .

:MN1957
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.7:out:0" ;
      isa:hasMaterial :M2382 ;
      isa:hasStudy :S2 .

:MN582
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.30" ;
      isa:hasInputNode :MN1594 ;
      isa:hasOutputNode :MN1828 ;
      isa:hasProtocolApplication
              :PA3445 ;
      isa:hasStudy :S2 .

:PA2610
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN1741
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.67:out:0" ;
      isa:hasMaterial :M3871 ;
      isa:hasStudy :S2 .

:M3397
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.1-aliquot2" .

:OE2604
      a       isa:OntologyEntry .

:DAN532
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.43" ;
      isa:hasInputNode :MN1494 ;
      isa:hasOutputNode :DN1980 ;
      isa:hasStudy :S2 .

:DN1817
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.3:out:0" ;
      isa:hasData :D3226 ;
      isa:hasStudy :S2 .

:PA2450
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:OE3276
      a       isa:OntologyEntry .

:FV3347
      a       isa:FactorValue .

:M2804
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_proteome.JC_N-0.2" .

:M2921
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:extract:a_microarray.NZ_1hrs_Drug_Sample_1_Extract" .

:MN1956
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.2:out:0" ;
      isa:hasMaterial :M2829 ;
      isa:hasStudy :S2 .

:MN859
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.74" ;
      isa:hasInputNode :MN1603 ;
      isa:hasOutputNode :MN1548 ;
      isa:hasStudy :S2 .

:D3384
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3939" ;
      dcterms:title "SCAN:MEXP:3939" .

:DAN533
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.42" ;
      isa:hasInputNode :MN1947 ;
      isa:hasOutputNode :DN1972 ;
      isa:hasStudy :S2 .

:MN857
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.72" ;
      isa:hasInputNode :MN2152 ;
      isa:hasOutputNode :MN1393 ;
      isa:hasStudy :S2 .

:MN583
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.33" ;
      isa:hasInputNode :MN2126 ;
      isa:hasOutputNode :MN2049 ;
      isa:hasProtocolApplication
              :PA3447 ;
      isa:hasStudy :S2 .

:DN2068
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.42:out:0" ;
      isa:hasData :D3589 ;
      isa:hasStudy :S2 .

:DN1973
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.35:out:0" ;
      isa:hasData :D3104 ;
      isa:hasStudy :S2 .

:M3325
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC76_Phosphate_0.10_External_1_1" .

:MN1740
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.22:out:0" ;
      isa:hasMaterial :M3323 ;
      isa:hasStudy :S2 .

:PA3485
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:DN1816
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.2:out:0" ;
      isa:hasData :D3224 ;
      isa:hasStudy :S2 .

:D3049
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC79_Phosphate_0.20_External_1_1.txt" ;
      dcterms:title "JIC79_Phosphate_0.20_External_1_1.txt" .

:PA2238
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2805
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_proteome.8762" .

:M2672
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.S-0.2-aliquot5" .

:M2685
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3947" .

:MN858
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.71" ;
      isa:hasInputNode :MN2087 ;
      isa:hasOutputNode :MN1589 ;
      isa:hasStudy :S2 .

:OE3840
      a       isa:OntologyEntry .

:OE3695
      a       isa:OntologyEntry .

:MN1806
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.5:out:0" ;
      isa:hasMaterial :M2807 ;
      isa:hasStudy :S2 .

:MN11
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.26" ;
      isa:hasInputNode :MN2164 ;
      isa:hasOutputNode :MN1750 ;
      isa:hasProtocolApplication
              :PA2244 ;
      isa:hasStudy :S2 .

:OE3110
      a       isa:OntologyEntry .

:DN1693
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.35:out:0" ;
      isa:hasData :D3601 ;
      isa:hasStudy :S2 .

:DN1610
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.1:out:0" ;
      isa:hasData :D3291 ;
      isa:hasStudy :S1 .

:PA2673
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:OE2602
      a       isa:OntologyEntry .

:MN584
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.32" ;
      isa:hasInputNode :MN1404 ;
      isa:hasOutputNode :MN1702 ;
      isa:hasProtocolApplication
              :PA3449 ;
      isa:hasStudy :S2 .

:PA2721
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:DN2204
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.34:out:0" ;
      isa:hasData :D3735 ;
      isa:hasStudy :S2 .

:D3165
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC70_Nitrogen_0.20_External_1_1.txt" ;
      dcterms:title "JIC70_Nitrogen_0.20_External_1_1.txt" .

:MN1807
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.32:out:0" ;
      isa:hasMaterial :M2532 ;
      isa:hasStudy :S2 .

:D2705
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_normalized_data:a_proteome.norm1" ;
      dcterms:title "norm1" .

:MN12
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.4" ;
      isa:hasInputNode :MN1804 ;
      isa:hasOutputNode :MN2076 ;
      isa:hasProtocolApplication
              :PA2247 ;
      isa:hasStudy :S2 .

:DN1691
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.1:out:0" ;
      isa:hasData :D2582 ;
      isa:hasStudy :S2 .

:M2321
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.N-0.1-aliquot10" .

:PA2340
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN1522
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.38:out:0" ;
      isa:hasMaterial :M2556 ;
      isa:hasStudy :S2 .

:PA3692
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN585
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.35" ;
      isa:hasInputNode :MN1784 ;
      isa:hasOutputNode :MN1885 ;
      isa:hasProtocolApplication
              :PA3451 ;
      isa:hasStudy :S2 .

:OE3549
      a       isa:OntologyEntry .

:M2730
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3931" .

:M3768
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.N-0.1-aliquot8" .

:M2320
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.1-aliquot10" .

:DN1690
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.24:out:0" ;
      isa:hasData :D3517 ;
      isa:hasStudy :S2 .

:MN1526
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.58:out:0" ;
      isa:hasMaterial :M2365 ;
      isa:hasStudy :S2 .

:MN707
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.28" ;
      isa:hasInputNode :MN1881 ;
      isa:hasOutputNode :MN1510 ;
      isa:hasStudy :S2 .

:DN1978
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.30:out:0" ;
      isa:hasData :D3080 ;
      isa:hasStudy :S2 .

:FV3738
      a       isa:FactorValue .

:DAN322
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.80" ;
      isa:hasInputNode :MN2201 ;
      isa:hasOutputNode :DN1662 ;
      isa:hasStudy :S2 .

:MN586
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.34" ;
      isa:hasInputNode :MN1953 ;
      isa:hasOutputNode :MN1697 ;
      isa:hasProtocolApplication
              :PA3453 ;
      isa:hasStudy :S2 .

:MN1670
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.103:out:0" ;
      isa:hasMaterial :M2976 ;
      isa:hasStudy :S2 .

:OE3616
      a       isa:OntologyEntry .

:D3163
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC63_Carbon_0.20_External_3_1.txt" ;
      dcterms:title "JIC63_Carbon_0.20_External_3_1.txt" .

:MN1898
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.12:out:0" ;
      isa:hasMaterial :M3395 ;
      isa:hasStudy :S2 .

:DN1753
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.14:out:0" ;
      isa:hasData :D3542 ;
      isa:hasStudy :S2 .

:PA2809
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:P_1110
      a       isa:Protocol ;
      rdfs:label "EukGE-WS4"^^xsd:string ;
      isa:hasAccessionID "BII-S-2\\EukGE-WS4" ;
      dcterms:description "For each target, a hybridisation cocktail was made using the standard array recipe as described in the GeneChip �_� Expression Analysis technical manual. GeneChip �_� control oligonucleotide and 20x eukaryotic hybridisation controls were used. Hybridisation buffer was made as detailed in the GeneChip �_� manual and the BSA and herring sperm DNA was purchased from Invitrogen. The cocktail was heated to 99 C for 5mins, transferred to 45 C for 5 min and then spun for 5 min to remove any insoluble material. Affymetrix Yeast Yg_s98 S. cerevisiae arrays were pre-hybridised with 200 �_�l 1x hybridisation buffer and incubated at 45 C for 10 min. 200 �_�l of the hybridisation cocktail was loaded onto the arrays. The probe array was incubated in a rotisserie at 45 C, rotating at 60 rpm. Following hybridisation, for 16hr, chips were loaded onto a Fluidics station for washing and staining using the EukGe WS2v4 programme controlled using Microarray Suite 5 software." .

:D2707
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_derived_data:a_proteome.datatransformation1" ;
      isa:hasFactorValue :FV2710 , :FV2709 ;
      dcterms:title "datatransformation1" .

:M2681
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3953" .

:D2637
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3911" ;
      dcterms:title "SCAN:MEXP:3911" .

:MN1959
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.16:out:0" ;
      isa:hasMaterial :M2452 ;
      isa:hasStudy :S2 .

:MN10
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.25" ;
      isa:hasInputNode :MN2210 ;
      isa:hasOutputNode :MN2103 ;
      isa:hasProtocolApplication
              :PA2241 ;
      isa:hasStudy :S2 .

:PA3489
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:PA2670
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:DPN847
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.7" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1585 ;
      isa:hasStudy :S2 .

:MN587
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.37" ;
      isa:hasInputNode :MN1927 ;
      isa:hasOutputNode :MN1668 ;
      isa:hasProtocolApplication
              :PA3455 ;
      isa:hasStudy :S2 .

:DAN323
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.81" ;
      isa:hasInputNode :MN2034 ;
      isa:hasOutputNode :DN1455 ;
      isa:hasStudy :S2 .

:FV3737
      a       isa:FactorValue .

:A1310
      a       isa:Assay .

:P_1111
      a       isa:Protocol ;
      rdfs:label "growth protocol"^^xsd:string ;
      isa:hasAccessionID "BII-S-1\\growth protocol" ;
      dcterms:description """1. Biomass samples (45 ml) were taken via the sample port of the Applikon fermenters. The cells were pelleted by centrifugation for 5 min at 5000 rpm. The supernatant was removed and the RNA pellet resuspended in the residual medium to form a slurry. This was added in a dropwise manner directly into a 5 ml Teflon flask (B. Braun Biotech, Germany) containing liquid nitrogen and a 7 mm-diameter tungsten carbide ball. After allowing evaporation of the liquid nitrogen the flask was reassembled and the cells disrupted by agitation at 1500 rpm for 2 min in a Microdismembranator U (B. Braun Biotech, Germany) 

2. The frozen powder was then dissolved in 1 ml of TriZol reagent (Sigma-Aldrich, UK), vortexed for 1 min, and then kept at room temperature for a further 5min. 

3. Chloroform extraction was performed by addition of 0.2 ml chloroform, shaking vigorously or 15 s, then 5min incubation at room temperature. 

4. Following centrifugation at 12,000 rpm for 5 min, the RNA (contained in the aqueous phase) was precipitated with 0.5 vol of 2-propanol at room temperature for 15 min. 
5. After further centrifugation (12,000 rpm for 10 min at 4 C) the RNA pellet was washed twice with 70 % (v/v) ethanol, briefly air-dried, and redissolved in 0.5 ml diethyl pyrocarbonate (DEPC)-treated water. 

6. The single-stranded RNA was precipitated once more by addition of 0.5 ml of LiCl buffer (4 M LiCl, 20 mM Tris-HCl, pH 7.5, 10 mM EDTA), thus removing tRNA and DNA from the sample. 

7. After precipitation (20 C for 1h) and centrifugation (12,000 rpm, 30 min, 4 C), the RNA was washed twice in 70 % (v/v) ethanol prior to being dissolved in a minimal volume of DEPC-treated water.

 8. Total RNA quality was checked using the RNA 6000 Nano Assay, and analysed on an Agilent 2100 Bioanalyser (Agilent Technologies). RNA was quantified using the Nanodrop ultra low volume spectrophotometer (Nanodrop Technologies).""" .

:FV3732
      a       isa:FactorValue .

:PA2725
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:M2732
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.07-aliquot6" .

:M2326
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.1-aliquot8" .

:DN2062
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.20:out:0" ;
      isa:hasData :D3026 ;
      isa:hasStudy :S2 .

:OE3546
      a       isa:OntologyEntry .

:PA2343
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:OE3614
      a       isa:OntologyEntry .

:MN588
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.36" ;
      isa:hasInputNode :MN1904 ;
      isa:hasOutputNode :MN2003 ;
      isa:hasProtocolApplication
              :PA3457 ;
      isa:hasStudy :S2 .

:MN1672
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.74:out:0" ;
      isa:hasMaterial :M3482 ;
      isa:hasStudy :S2 .

:P_1112
      a       isa:Protocol ;
      rdfs:label "mRNA extraction"^^xsd:string ;
      isa:hasAccessionID "BII-S-1\\mRNA extraction" ;
      dcterms:description """1. Biomass samples (45 ml) were taken via the sample port of the Applikon fermenters. The cells were pelleted by centrifugation for 5 min at 5000 rpm. The supernatant was removed and the RNA pellet resuspended in the residual medium to form a slurry. This was added in a dropwise manner directly into a 5 ml Teflon flask (B. Braun Biotech, Germany) containing liquid nitrogen and a 7 mm-diameter tungsten carbide ball. After allowing evaporation of the liquid nitrogen the flask was reassembled and the cells disrupted by agitation at 1500 rpm for 2 min in a Microdismembranator U (B. Braun Biotech, Germany) 

2. The frozen powder was then dissolved in 1 ml of TriZol reagent (Sigma-Aldrich, UK), vortexed for 1 min, and then kept at room temperature for a further 5min. 

3. Chloroform extraction was performed by addition of 0.2 ml chloroform, shaking vigorouslyor 15 s, then 5min incubation at room temperature. 

4. Following centrifugation at 12,000 rpm for 5 min, the RNA (contained in the aqueous phase) was precipitated with 0.5 vol of 2-propanol at room temperature for 15 min. 
5. After further centrifugation (12,000 rpm for 10 min at 4 C) the RNA pellet was washed twice with 70 % (v/v) ethanol, briefly air-dried, and redissolved in 0.5 ml diethyl pyrocarbonate (DEPC)-treated water. 

6. The single-stranded RNA was precipitated once more by addition of 0.5 ml of LiCl bffer (4 M LiCl, 20 mM Tris-HCl, pH 7.5, 10 mM EDTA), thus removing tRNA and DNA from the sample. 

7. After precipitation (20 C for 1 h) and centrifugation (12,000 rpm, 30 min, 4 C), the RNA was washed twice in 70 % (v/v) ethanol prior to being dissolved in a minimal volume of DEPC-treated water.

 8. Total RNA quality was checked using the RNA 6000 Nano Assay, and analysed on an Agilent 2100 Bioanalyser (Agilent Technologies). RNA was quantified using the Nanodrop ultra low volume spectrophotometer (Nanodrop Technologies).""" .

:DN1544
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.10:out:0" ;
      isa:hasData :D3348 ;
      isa:hasStudy :S1 .

:D2639
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3911" ;
      isa:hasFactorValue :FV2642 , :FV2641 ;
      dcterms:title "SCAN:MEXP:3911" .

:OE3271
      a       isa:OntologyEntry .

:D3160
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC69_Nitrogen_0.10_External_3_1.txt" ;
      dcterms:title "JIC69_Nitrogen_0.10_External_3_1.txt" .

:ISA_1113
      a       foaf:Person , isa:Contact ;
      foaf:family_name "Leo"^^xsd:string ;
      foaf:givenname "Zeef"^^xsd:string .

:MN1895
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.59:out:0" ;
      isa:hasMaterial :M3822 ;
      isa:hasStudy :S2 .

:MN1671
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.66:out:0" ;
      isa:hasMaterial :M2733 ;
      isa:hasStudy :S2 .

:MN589
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.38" ;
      isa:hasInputNode :MN2192 ;
      isa:hasOutputNode :MN1364 ;
      isa:hasProtocolApplication
              :PA3459 ;
      isa:hasStudy :S2 .

:DN1756
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.0:out:0" ;
      isa:hasData :D2593 ;
      isa:hasStudy :S2 .

:DPN849
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.6" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1585 ;
      isa:hasStudy :S2 .

:DN1543
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.41:out:0" ;
      isa:hasData :D3144 ;
      isa:hasStudy :S2 .

:PA2767
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2324
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.N-0.07-aliquot10" .

:MN1804
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.4:out:0" ;
      isa:hasMaterial :M2248 ;
      isa:hasStudy :S2 .

:FV3295
      a       isa:FactorValue .

:M3619
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.2-aliquot10" .

:M2520
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.P-0.2-aliquot9" .

:PA2723
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN850
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.129" ;
      isa:hasInputNode :MN1335 ;
      isa:hasOutputNode :MN1436 ;
      isa:hasProtocolApplication
              :PA3875 ;
      isa:hasStudy :S2 .

:MN1894
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.99:out:0" ;
      isa:hasMaterial :M3462 ;
      isa:hasStudy :S2 .

:MN1388
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.3:out:0" ;
      isa:hasMaterial :M2625 ;
      isa:hasStudy :S2 .

:MN1521
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.108:out:0" ;
      isa:hasMaterial :M2916 ;
      isa:hasStudy :S2 .

:DAN326
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.79" ;
      isa:hasInputNode :MN1775 ;
      isa:hasOutputNode :DN1864 ;
      isa:hasStudy :S2 .

:MN1674
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.4:out:0" ;
      isa:hasMaterial :M2735 ;
      isa:hasStudy :S2 .

:DN1757
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.9:out:0" ;
      isa:hasData :D2649 ;
      isa:hasStudy :S2 .

:FV3733
      a       isa:FactorValue .

:M2733
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.C-0.07-aliquot6" .

:M2323
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.07-aliquot10" .

:DAN328
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.78" ;
      isa:hasInputNode :MN1551 ;
      isa:hasOutputNode :DN1876 ;
      isa:hasStudy :S2 .

:FV3294
      a       isa:FactorValue .

:OE3543
      a       isa:OntologyEntry .

:M3618
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.07-aliquot5" .

:MN1805
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.84:out:0" ;
      isa:hasMaterial :M2998 ;
      isa:hasStudy :S2 .

:MN1893
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.146:out:0" ;
      isa:hasMaterial :M2834 ;
      isa:hasStudy :S2 .

:PA2346
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN1389
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.19:out:0" ;
      isa:hasMaterial :M2464 ;
      isa:hasStudy :S2 .

:PA2957
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:DN1744
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.57:out:0" ;
      isa:hasData :D3132 ;
      isa:hasStudy :S2 .

:MN577
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.15" ;
      isa:hasInputNode :MN1565 , :MN1634 ;
      isa:hasOutputNode :MN1814 ;
      isa:hasProtocolApplication
              :PA3438 ;
      isa:hasStudy :S2 .

:MN1500
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.11:out:0" ;
      isa:hasMaterial :M2805 ;
      isa:hasStudy :S2 .

:PA3679
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:PA3465
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:PA2591
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:D3525
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3938" ;
      dcterms:title "SCAN:MEXP:3938" .

:MN1481
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.25:out:0" ;
      isa:hasMaterial :M2486 ;
      isa:hasStudy :S2 .

:M3167
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC46_GlucoseO2_0.07_Internal_1_1" .

:M2790
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.1-aliquot7" .

:M2454
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.N-0.1-aliquot2" .

:MN1839
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.33:out:0" ;
      isa:hasMaterial :M3409 ;
      isa:hasStudy :S2 .

:MN1405
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.10:out:0" ;
      isa:hasMaterial :M3399 ;
      isa:hasStudy :S2 .

:M3474
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.07-aliquot1" .

:MN576
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.12" ;
      isa:hasInputNode :MN1565 ;
      isa:hasOutputNode :MN1392 ;
      isa:hasProtocolApplication
              :PA3435 ;
      isa:hasStudy :S2 .

:DAN562
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.8" ;
      isa:hasInputNode :MN1652 ;
      isa:hasOutputNode :DN2128 ;
      isa:hasStudy :S2 .

:MN1482
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.11:out:0" ;
      isa:hasMaterial :M3656 ;
      isa:hasStudy :S2 .

:DAN397
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.43" ;
      isa:hasInputNode :MN1506 ;
      isa:hasOutputNode :DN1699 ;
      isa:hasStudy :S2 .

:D2595
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3908" ;
      isa:hasFactorValue :FV2597 , :FV2598 ;
      dcterms:title "SCAN:MEXP:3908" .

:M2455
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.N-0.1-aliquot2" .

:MN1725
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.27:out:0" ;
      isa:hasMaterial :M3335 ;
      isa:hasStudy :S2 .

:MN1404
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.85:out:0" ;
      isa:hasMaterial :M3450 ;
      isa:hasStudy :S2 .

:M3698
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.1-aliquot5" .

:DAN561
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.9" ;
      isa:hasInputNode :MN2000 ;
      isa:hasOutputNode :DN1757 ;
      isa:hasStudy :S2 .

:D3523
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3935" ;
      dcterms:title "SCAN:MEXP:3935" .

:PA3467
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN579
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.97" ;
      isa:hasInputNode :MN1361 ;
      isa:hasOutputNode :MN2083 ;
      isa:hasStudy :S2 .

:M3472
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.07-aliquot2" .

:MN2060
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.44:out:0" ;
      isa:hasMaterial :M2297 ;
      isa:hasStudy :S2 .

:MN720
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.26" ;
      isa:hasInputNode :MN1851 ;
      isa:hasOutputNode :MN1886 ;
      isa:hasStudy :S2 .

:MN1402
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.5:out:0" ;
      isa:hasMaterial :M3507 ;
      isa:hasStudy :S2 .

:DAN456
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.0" ;
      isa:hasInputNode :MN1380 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:PA3734
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:PA2500
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN1040
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.93" ;
      isa:hasInputNode :MN1367 ;
      isa:hasOutputNode :MN1584 ;
      isa:hasProtocolApplication
              :PA3960 ;
      isa:hasStudy :S2 .

:MN1728
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.13:out:0" ;
      isa:hasMaterial :M3257 ;
      isa:hasStudy :S2 .

:M2452
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.N-0.1-aliquot1" .

:M2810
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:G-0.1-aliquot2" .

:OE3048
      a       isa:OntologyEntry .

:PA2980
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:DN1858
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.19:out:0" ;
      isa:hasData :D3016 ;
      isa:hasStudy :S2 .

:MN1484
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.15:out:0" ;
      isa:hasMaterial :M2448 ;
      isa:hasStudy :S2 .

:MN721
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.14" ;
      isa:hasInputNode :MN1339 ;
      isa:hasOutputNode :MN1597 ;
      isa:hasProtocolApplication
              :PA3711 ;
      isa:hasStudy :S2 .

:MN578
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.98" ;
      isa:hasInputNode :MN1874 ;
      isa:hasOutputNode :MN2119 ;
      isa:hasStudy :S2 .

:MN1727
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.61:out:0" ;
      isa:hasMaterial :M2742 ;
      isa:hasStudy :S2 .

:M2811
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.G-0.1-aliquot2" .

:DPN525
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      dcterms:abstract """Background
Cell growth underlies many key cellular and developmental processes, yet a limited number of studies have been carried out on cell-growth regulation. Comprehensive studies at the transcriptional, proteomic and metabolic levels under defined controlled conditions are currently lacking.
Results
Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each functional genomic level shows clear growth-rate-associated trends and discriminates between carbon-sufficient and carbon-limited conditions. Genes consistently and significantly upregulated with increasing growth rate are frequently essential and encode evolutionarily conserved proteins of known function that participate in many protein-protein interactions. In contrast, more unknown, and fewer essential, genes are downregulated with increasing growth rate; their protein products rarely interact with one another. A large proportion of yeast genes under positive growth-rate control share orthologs with other eukaryotes, including humans. Significantly, transcription of genes encoding components of the TOR complex (a major controller of eukaryotic cell growth) is not subject to growth-rate regulation. Moreover, integrative studies reveal the extent and importance of post-transcriptional control, patterns of control of metabolic fluxes at the level of enzyme synthesis, and the relevance of specific enzymatic reactions in the control of metabolic fluxes during cell growth.
Conclusion
This work constitutes a first comprehensive systems biology study on growth-rate control in the eukaryotic cell. The results have direct implications for advanced studies on cell growth, in vivo regulation of metabolic fluxes for comprehensive metabolic engineering, and for the design of genome-scale systems biology models of the eukaryotic cell.""" ;
      dcterms:created "29 Apr 2007 20:00:00 GMT" ;
      dcterms:issued "9 Mar 2009 21:00:00 GMT" ;
      dcterms:title "Growth control of the eukaryote cell: a systems biology study in yeast" .

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:PA3949
      a       isa:ProtocolApplication ;
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              :PA3962 ;
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      a       isa:Assay .

:PA3461
      a       isa:ProtocolApplication ;
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:PA2441
      a       isa:ProtocolApplication ;
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:PA3889
      a       isa:ProtocolApplication ;
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:DAN567
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              :PA3645 ;
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:D3378
      a       isa:Data ;
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:OE3385
      a       isa:OntologyEntry .

:OE3156
      a       isa:OntologyEntry .

:DPN851
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:M2327
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      a       isa:MaterialNode ;
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      a       isa:MaterialNode ;
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      a       isa:MaterialProcessing ;
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      isa:hasProtocolApplication
              :PA3961 ;
      isa:hasStudy :S2 .

:A1266
      a       isa:Assay .

:MN1941
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:OE3847
      a       isa:OntologyEntry .

:PA3888
      a       isa:ProtocolApplication ;
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:MN685
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1348 ;
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:DPN462
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      isa:hasInputNode :DN1876 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1339 ;
      isa:hasOutputNode :MN1477 ;
      isa:hasProtocolApplication
              :PA3713 ;
      isa:hasStudy :S2 .

:MN228
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1968 ;
      isa:hasOutputNode :MN2211 ;
      isa:hasProtocolApplication
              :PA2838 ;
      isa:hasStudy :S2 .

isa:Accessible
      rdfs:subClassOf isa:Annotatable .

:M2561
      a       isa:Material ;
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:MN1837
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1339 ;
      isa:hasOutputNode :MN1898 ;
      isa:hasProtocolApplication
              :PA3900 ;
      isa:hasStudy :S2 .

:A1269
      a       isa:Assay .

:PA3463
      a       isa:ProtocolApplication ;
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:MN2122
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.78:out:0" ;
      isa:hasMaterial :M3884 ;
      isa:hasStudy :S2 .

:DAN565
      a       isa:DataAcquisition ;
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      isa:hasOutputNode :DN1333 ;
      isa:hasStudy :S2 .

dcterms:hasVersion
      a       owl:AnnotationProperty .

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      isa:hasStudy :S2 .

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      a       isa:MaterialNode ;
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      isa:hasMaterial :M2517 ;
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      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1881 ;
      isa:hasStudy :S2 .

:DN1512
      a       isa:DataNode ;
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      isa:hasData :D3380 ;
      isa:hasStudy :S2 .

:D3376
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3946" ;
      dcterms:title "SCAN:MEXP:3946" .

:MN688
      a       isa:MaterialProcessing ;
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      a       isa:MaterialProcessing ;
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              :PA2833 ;
      isa:hasStudy :S2 .

:OE3387
      a       isa:OntologyEntry .

:PA2870
      a       isa:ProtocolApplication ;
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:MN726
      a       isa:MaterialProcessing ;
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:M2562
      a       isa:Material ;
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:M2329
      a       isa:Material ;
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:MN949
      a       isa:MaterialProcessing ;
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      isa:hasStudy :S2 .

:M2791
      a       isa:Material ;
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:MN1836
      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:PA2503
      a       isa:ProtocolApplication ;
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:DPN464
      a       isa:DataProcessing ;
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      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DAN564
      a       isa:DataAcquisition ;
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      isa:hasOutputNode :DN1352 ;
      isa:hasStudy :S2 .

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      a       isa:DataNode ;
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      isa:hasData :D3511 ;
      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1674 ;
      isa:hasProtocolApplication
              :PA3963 ;
      isa:hasStudy :S2 .

:A1268
      a       isa:Assay .

:DN1511
      a       isa:DataNode ;
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      isa:hasData :D3565 ;
      isa:hasStudy :S2 .

:DAN451
      a       isa:DataAcquisition ;
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      isa:hasOutputNode :DN2099 ;
      isa:hasStudy :S2 .

:MN1375
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2899 ;
      isa:hasStudy :S2 .

:OE3306
      a       isa:OntologyEntry .

:D2593
      a       isa:Data ;
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:MN226
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN2182 ;
      isa:hasOutputNode :MN1380 ;
      isa:hasStudy :S2 .

:MN1018
      a       isa:MaterialProcessing ;
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      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasProtocolApplication
              :PA3651 ;
      isa:hasStudy :S2 .

:MN1377
      a       isa:MaterialNode ;
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:MN2129
      a       isa:MaterialNode ;
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:PA2432
      a       isa:ProtocolApplication ;
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:D3593
      a       isa:Data ;
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:DPN302
      a       isa:DataProcessing ;
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:DAN293
      a       isa:DataAcquisition ;
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      isa:hasStudy :S2 .

:A1258
      a       isa:Assay .

:D3170
      a       isa:Data ;
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:D2629
      a       isa:Data ;
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      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1998 ;
      isa:hasProtocolApplication
              :PA2337 ;
      isa:hasStudy :S2 .

:PA3957
      a       isa:ProtocolApplication ;
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:MN959
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN2087 ;
      isa:hasStudy :S2 .

:DN2071
      a       isa:DataNode ;
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      isa:hasData :D3085 ;
      isa:hasStudy :S2 .

:PA3946
      a       isa:ProtocolApplication ;
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:MN1603
      a       isa:MaterialNode ;
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:M2335
      a       isa:Material ;
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:MN1019
      a       isa:MaterialProcessing ;
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      isa:hasStudy :S2 .

:FV2892
      a       isa:FactorValue .

:MN1376
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2931 ;
      isa:hasStudy :S1 .

:MN1601
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2327 ;
      isa:hasStudy :S2 .

:OE3159
      a       isa:OntologyEntry .

:MN1017
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1777 ;
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:DPN392
      a       isa:DataProcessing ;
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      isa:hasStudy :S2 .

:A1259
      a       isa:Assay .

:DPN303
      a       isa:DataProcessing ;
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      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DN2120
      a       isa:DataNode ;
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      isa:hasData :D3090 ;
      isa:hasStudy :S2 .

:OE3532
      a       isa:OntologyEntry .

:PA3958
      a       isa:ProtocolApplication ;
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:MN41
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1761 ;
      isa:hasProtocolApplication
              :PA2334 ;
      isa:hasStudy :S2 .

:FV2893
      a       isa:FactorValue .

:DN2072
      a       isa:DataNode ;
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      isa:hasData :D3155 ;
      isa:hasStudy :S2 .

:DAN339
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN2119 ;
      isa:hasOutputNode :DN1783 ;
      isa:hasStudy :S2 .

:M2336
      a       isa:Material ;
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:MN148
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1342 ;
      isa:hasOutputNode :MN1914 ;
      isa:hasProtocolApplication
              :PA2670 ;
      isa:hasStudy :S2 .

:MN1600
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2284 ;
      isa:hasStudy :S2 .

:DPN395
      a       isa:DataProcessing ;
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      isa:hasInputNode :DN2140 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:PA3890
      a       isa:ProtocolApplication ;
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:M3013
      a       isa:Material ;
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:MN2127
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2768 ;
      isa:hasStudy :S2 .

:MN956
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1943 ;
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:MN957
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1603 ;
      isa:hasStudy :S2 .

:PA3948
      a       isa:ProtocolApplication ;
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:DN2073
      a       isa:DataNode ;
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      isa:hasData :D2972 ;
      isa:hasStudy :S2 .

:PA3959
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:M2952
      a       isa:Material ;
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:FV3630
      a       isa:FactorValue .

:FV3568
      a       isa:FactorValue .

:MN44
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1815 ;
      isa:hasOutputNode :MN1682 ;
      isa:hasProtocolApplication
              :PA2343 ;
      isa:hasStudy :S2 .

:MN1378
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2889 ;
      isa:hasStudy :S2 .

:MN149
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1624 ;
      isa:hasOutputNode :MN1746 ;
      isa:hasProtocolApplication
              :PA2673 ;
      isa:hasStudy :S2 .

:DPN394
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              :PA2841 ;
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      a       isa:ProtocolApplication ;
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      a       isa:ProtocolApplication ;
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      a       isa:Material ;
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isa:hasMaterial
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      a       isa:FactorValue .

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isa:Investigation
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      a       isa:ProtocolApplication ;
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      a       isa:ProtocolApplication ;
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:PA3892
      a       isa:ProtocolApplication ;
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:D3597
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:D3382
      a       isa:Data ;
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      a       isa:ProtocolApplication ;
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      a       isa:ProtocolApplication ;
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:OE3536
      a       isa:OntologyEntry .

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              :PA2951 ;
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              :PA3893 ;
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:M2558
      a       isa:Material ;
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dcterms:title
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      a       isa:Material ;
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      a       isa:ProtocolApplication ;
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:D3380
      a       isa:Data ;
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:OE3538
      a       isa:OntologyEntry .

:OE3852
      a       isa:OntologyEntry .

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              :PA2352 ;
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:DAN331
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              :PA3795 ;
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:D3868
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isa:DataProcessing
      rdfs:subClassOf isa:Processing .

:OE3741
      a       isa:OntologyEntry .

:M2816
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:M2899
      a       isa:Material ;
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:D3014
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:PA3950
      a       isa:ProtocolApplication ;
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:OE3002
      a       isa:OntologyEntry .

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:OE3005
      a       isa:OntologyEntry .

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      a       isa:ProtocolApplication ;
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:DAN333
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:PA3940
      a       isa:ProtocolApplication ;
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:PA3951
      a       isa:ProtocolApplication ;
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:M2897
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:M2959
      a       isa:Material ;
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      a       isa:Material ;
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:FV3636
      a       isa:FactorValue .

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:OE3641
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isa:ParameterValue
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              :PA3874 ;
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              :PA2331 ;
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      isa:hasOutputNode :MN1665 ;
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              :PA2663 ;
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:A1124
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:DAN444
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      a       isa:ProtocolApplication ;
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      a       isa:Data ;
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      a       isa:Data ;
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:A1123
      a       isa:Assay .

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      a       isa:Data ;
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      a       isa:ProtocolApplication ;
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dcterms:created
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:MN566
      a       isa:MaterialProcessing ;
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              :PA3429 ;
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:OE3037
      a       isa:OntologyEntry .

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      a       isa:OntologyEntry .

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      a       isa:ProtocolApplication ;
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      a       isa:Assay .

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      a       isa:ProtocolApplication ;
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      a       isa:Material ;
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:OE3310
      a       isa:OntologyEntry .

:PA3457
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:A1271
      a       isa:Assay .

:OE2967
      a       isa:OntologyEntry .

:DN1635
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.18:out:0" ;
      isa:hasData :D3554 ;
      isa:hasStudy :S2 .

:MN1581
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.0.2.7:out:0" ;
      isa:hasMaterial :M2419 ;
      isa:hasStudy :S2 .

:MN1937
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.2:out:0" ;
      isa:hasMaterial :M2270 ;
      isa:hasStudy :S2 .

:M2446
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.N-0.07-aliquot3" .

:M3151
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC60_Carbon_0.10_External_3_1" .

:M3466
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.2-aliquot2" .

:M2824
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:G-0.1-aliquot6" .

:OE3030
      a       isa:OntologyEntry .

:A1270
      a       isa:Assay .

:OE3746
      a       isa:OntologyEntry .

:MN560
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.19" ;
      isa:hasInputNode :MN2025 ;
      isa:hasOutputNode :MN1331 ;
      isa:hasProtocolApplication
              :PA3426 ;
      isa:hasStudy :S2 .

:DN1529
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.108:out:0" ;
      isa:hasData :D3853 ;
      isa:hasStudy :S2 .

:MN1938
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.110:out:0" ;
      isa:hasMaterial :M2953 ;
      isa:hasStudy :S2 .

:M2600
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3913" .

:PA2864
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2825
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.G-0.1-aliquot6" .

:OE3312
      a       isa:OntologyEntry .

:MN39
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.32" ;
      isa:hasInputNode :MN1343 ;
      isa:hasOutputNode :MN1776 ;
      isa:hasProtocolApplication
              :PA2328 ;
      isa:hasStudy :S2 .

:M3468
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.2-aliquot1" .

:M2553
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:hybridization:a_microarray.NZ_1hrs_Drug_Sample_2_Labelled_Hyb4" .

:FV3583
      a       isa:FactorValue .

:MN1820
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.23:out:0" ;
      isa:hasMaterial :M2493 ;
      isa:hasStudy :S2 .

:PA3899
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:D3360
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3953" ;
      dcterms:title "SCAN:MEXP:3953" .

:MN672
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.18" ;
      isa:hasInputNode :MN1735 ;
      isa:hasOutputNode :MN2153 ;
      isa:hasStudy :S2 .

:OE3518
      a       isa:OntologyEntry .

:DPN249
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.10" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1585 ;
      isa:hasStudy :S2 .

:DAN663
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.20" ;
      isa:hasInputNode :MN2036 ;
      isa:hasOutputNode :DN1913 ;
      isa:hasStudy :S2 .

:MN1930
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.47:out:0" ;
      isa:hasMaterial :M2681 ;
      isa:hasStudy :S2 .

:A1277
      a       isa:Assay .

:OE3856
      a       isa:OntologyEntry .

:MN2130
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.51:out:0" ;
      isa:hasMaterial :M2320 ;
      isa:hasStudy :S2 .

:MN1036
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.95" ;
      isa:hasInputNode :MN1367 ;
      isa:hasOutputNode :MN1406 ;
      isa:hasProtocolApplication
              :PA3956 ;
      isa:hasStudy :S2 .

:D3640
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3920" ;
      isa:hasFactorValue :FV3643 , :FV3642 ;
      dcterms:title "SCAN:MEXP:3920" .

:MN1023
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.7" ;
      isa:hasInputNode :MN1465 ;
      isa:hasOutputNode :MN1957 ;
      isa:hasProtocolApplication
              :PA3944 ;
      isa:hasStudy :S2 .

:DPN471
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.7.8.11" ;
      isa:hasInputNode :DN1585 ;
      isa:hasOutputNode :DN1399 ;
      isa:hasStudy :S2 .

:DN1591
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.25:out:0" ;
      isa:hasData :D3515 ;
      isa:hasStudy :S2 .

:M2718
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3930" .

:MN1932
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.21:out:0" ;
      isa:hasMaterial :M3254 ;
      isa:hasStudy :S2 .

:FV3584
      a       isa:FactorValue .

:DAN664
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.21" ;
      isa:hasInputNode :MN2172 ;
      isa:hasOutputNode :DN1602 ;
      isa:hasStudy :S2 .

:MN210
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.6" ;
      isa:hasInputNode :MN1487 ;
      isa:hasOutputNode :MN1500 ;
      isa:hasStudy :S2 .

:PA3390
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:DN1527
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.9:out:0" ;
      isa:hasData :D2651 ;
      isa:hasStudy :S2 .

:MN1931
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.109:out:0" ;
      isa:hasMaterial :M2956 ;
      isa:hasStudy :S2 .

:MN2131
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.109:out:0" ;
      isa:hasMaterial :M2901 ;
      isa:hasStudy :S2 .

:MN1035
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.98" ;
      isa:hasInputNode :MN1445 ;
      isa:hasOutputNode :MN2192 ;
      isa:hasProtocolApplication
              :PA3955 ;
      isa:hasStudy :S2 .

:A1276
      a       isa:Assay .

:DPN472
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.7.8.10" ;
      isa:hasInputNode :DN1585 ;
      isa:hasOutputNode :DN1399 ;
      isa:hasStudy :S2 .

dcterms:description
      a       owl:AnnotationProperty .

:MN1024
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.1" ;
      isa:hasInputNode :MN1375 ;
      isa:hasOutputNode :MN1706 ;
      isa:hasStudy :S2 .

:PA2861
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:PA2974
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN37
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.34" ;
      isa:hasInputNode :MN2188 ;
      isa:hasOutputNode :MN1519 ;
      isa:hasProtocolApplication
              :PA2322 ;
      isa:hasStudy :S2 .

:M2555
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.S-0.07-aliquot3" .

:MN1933
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.0:out:0" ;
      isa:hasMaterial :M2609 ;
      isa:hasStudy :S2 .

:OE3854
      a       isa:OntologyEntry .

:MN1021
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.32" ;
      isa:hasInputNode :MN1776 ;
      isa:hasOutputNode :MN1887 ;
      isa:hasStudy :S2 .

:MN670
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.19" ;
      isa:hasInputNode :MN1353 ;
      isa:hasOutputNode :MN1586 ;
      isa:hasStudy :S2 .

:D3362
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3951" ;
      dcterms:title "SCAN:MEXP:3951" .

:PA3897
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN211
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.5" ;
      isa:hasInputNode :MN1806 ;
      isa:hasOutputNode :MN1380 ;
      isa:hasStudy :S2 .

:DN1639
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.12:out:0" ;
      isa:hasData :D2880 ;
      isa:hasStudy :S1 .

:OE3516
      a       isa:OntologyEntry .

:A1275
      a       isa:Assay .

:MN1034
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.0" ;
      isa:hasInputNode :MN1465 ;
      isa:hasOutputNode :MN1717 ;
      isa:hasProtocolApplication
              :PA3954 ;
      isa:hasStudy :S2 .

:MN38
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.35" ;
      isa:hasInputNode :MN1383 ;
      isa:hasOutputNode :MN1601 ;
      isa:hasProtocolApplication
              :PA2325 ;
      isa:hasStudy :S2 .

:OE3140
      a       isa:OntologyEntry .

:M2716
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3935" .

:M2556
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.S-0.07-aliquot3" .

:FV2699
      a       isa:FactorValue .

:MN1934
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.155:out:0" ;
      isa:hasMaterial :M2799 ;
      isa:hasStudy :S2 .

:DN1525
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.84:out:0" ;
      isa:hasData :D2999 ;
      isa:hasStudy :S2 .

:OE2887
      a       isa:OntologyEntry .

:MN2133
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.50:out:0" ;
      isa:hasMaterial :M3817 ;
      isa:hasStudy :S2 .

:PA3896
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:PA2588
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:D3178
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC46_GlucoseO2_0.07_Internal_1_3.txt" ;
      dcterms:title "JIC46_GlucoseO2_0.07_Internal_1_3.txt" .

:MN1022
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.91" ;
      isa:hasInputNode :MN1367 ;
      isa:hasOutputNode :MN1742 ;
      isa:hasProtocolApplication
              :PA3942 ;
      isa:hasStudy :S2 .

:MN212
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.4" ;
      isa:hasInputNode :MN1806 ;
      isa:hasOutputNode :MN1380 ;
      isa:hasStudy :S2 .

:A1274
      a       isa:Assay .

:MN1033
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.97" ;
      isa:hasInputNode :MN1445 ;
      isa:hasOutputNode :MN1927 ;
      isa:hasProtocolApplication
              :PA3953 ;
      isa:hasStudy :S2 .

:DN1739
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.13:out:0" ;
      isa:hasData :D2878 ;
      isa:hasStudy :S1 .

:DPN470
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.7.8.12" ;
      isa:hasInputNode :DN1323 ;
      isa:hasOutputNode :DN1588 ;
      isa:hasStudy :S2 .

:PA3939
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN1825
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.80:out:0" ;
      isa:hasMaterial :M3898 ;
      isa:hasStudy :S2 .

:MN938
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.92" ;
      isa:hasInputNode :MN2121 ;
      isa:hasOutputNode :MN1495 ;
      isa:hasStudy :S2 .

:FV3587
      a       isa:FactorValue .

:M3798
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.N-0.1-aliquot7" .

:M3685
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.2-aliquot7" .

:OE3145
      a       isa:OntologyEntry .

:DAN440
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.4" ;
      isa:hasInputNode :MN1380 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:OE3317
      a       isa:OntologyEntry .

:MN736
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.22" ;
      isa:hasInputNode :MN1360 ;
      isa:hasOutputNode :MN2117 ;
      isa:hasProtocolApplication
              :PA3739 ;
      isa:hasStudy :S2 .

:OE3207
      a       isa:OntologyEntry .

:D3364
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3954" ;
      dcterms:title "SCAN:MEXP:3954" .

:MN213
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.90" ;
      isa:hasInputNode :MN1334 ;
      isa:hasOutputNode :MN1883 ;
      isa:hasProtocolApplication
              :PA2809 ;
      isa:hasStudy :S2 .

:MN676
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.16" ;
      isa:hasInputNode :MN1587 ;
      isa:hasOutputNode :MN1416 ;
      isa:hasStudy :S2 .

dcterms:abstract
      a       owl:AnnotationProperty .

:DPN475
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.81" ;
      isa:hasInputNode :DN1455 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DN1524
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.103:out:0" ;
      isa:hasData :D3834 ;
      isa:hasStudy :S2 .

:MN1032
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.1" ;
      isa:hasInputNode :MN1465 ;
      isa:hasOutputNode :MN1712 ;
      isa:hasProtocolApplication
              :PA3952 ;
      isa:hasStudy :S2 .

:PA3451
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN1362
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.59:out:0" ;
      isa:hasMaterial :M2379 ;
      isa:hasStudy :S2 .

:DAN667
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.16" ;
      isa:hasInputNode :MN1322 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:MN1719
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.57:out:0" ;
      isa:hasMaterial :M2347 ;
      isa:hasStudy :S2 .

:DAN669
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.10" ;
      isa:hasInputNode :MN1500 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:M2550
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:extract:a_microarray.NZ_1hrs_Vehicle_Sample_2_Extract" .

:PA3749
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN937
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.91" ;
      isa:hasInputNode :MN1498 ;
      isa:hasOutputNode :MN1792 ;
      isa:hasStudy :S2 .

:MN1824
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.81:out:0" ;
      isa:hasMaterial :M3895 ;
      isa:hasStudy :S2 .

:FV3588
      a       isa:FactorValue .

:MN738
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.21" ;
      isa:hasInputNode :MN1360 ;
      isa:hasOutputNode :MN1386 ;
      isa:hasProtocolApplication
              :PA3744 ;
      isa:hasStudy :S2 .

:M2714
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3938" .

:DN1523
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.63:out:0" ;
      isa:hasData :D3122 ;
      isa:hasStudy :S2 .

:MN1363
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.107:out:0" ;
      isa:hasMaterial :M2962 ;
      isa:hasStudy :S2 .

:MN1620
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.45:out:0" ;
      isa:hasMaterial :M3788 ;
      isa:hasStudy :S2 .

:MN214
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.91" ;
      isa:hasInputNode :MN2018 ;
      isa:hasOutputNode :MN1498 ;
      isa:hasProtocolApplication
              :PA2812 ;
      isa:hasStudy :S2 .

:DN1842
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.8:out:0" ;
      isa:hasData :D3298 ;
      isa:hasStudy :S1 .

:MN1020
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.31" ;
      isa:hasInputNode :MN1776 ;
      isa:hasOutputNode :MN1887 ;
      isa:hasStudy :S2 .

:DAN668
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.15" ;
      isa:hasInputNode :MN1322 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:MN1031
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.99" ;
      isa:hasInputNode :MN1445 ;
      isa:hasOutputNode :MN1894 ;
      isa:hasProtocolApplication
              :PA3951 ;
      isa:hasStudy :S2 .

:PA3394
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:PA3937
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:PA2703
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN1823
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.47:out:0" ;
      isa:hasMaterial :M2341 ;
      isa:hasStudy :S2 .

:MN1718
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.59:out:0" ;
      isa:hasMaterial :M2368 ;
      isa:hasStudy :S2 .

:M3796
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.N-0.2-aliquot5" .

isa:HASREFERENCES
      rdfs:subClassOf isa:Accessible .

:DN1592
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.46:out:0" ;
      isa:hasData :D3170 ;
      isa:hasStudy :S2 .

:OE3143
      a       isa:OntologyEntry .

:DN1593
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.53:out:0" ;
      isa:hasData :D3191 ;
      isa:hasStudy :S2 .

:MN674
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.17" ;
      isa:hasInputNode :MN2145 ;
      isa:hasOutputNode :MN1313 ;
      isa:hasStudy :S2 .

:MN215
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.9" ;
      isa:hasInputNode :MN1640 ;
      isa:hasOutputNode :MN1500 ;
      isa:hasStudy :S2 .

:D3366
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3947" ;
      dcterms:title "SCAN:MEXP:3947" .

:MN1621
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.31:out:0" ;
      isa:hasMaterial :M2415 ;
      isa:hasStudy :S2 .

:MN734
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.23" ;
      isa:hasInputNode :MN1360 ;
      isa:hasOutputNode :MN2137 ;
      isa:hasProtocolApplication
              :PA3734 ;
      isa:hasStudy :S2 .

:OE3319
      a       isa:OntologyEntry .

:MN1360
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.22:in:0" ;
      isa:hasMaterial :M3627 ;
      isa:hasStudy :S2 .

:DAN665
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.14" ;
      isa:hasInputNode :MN1322 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:A1279
      a       isa:Assay .

:DAN442
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.50" ;
      isa:hasInputNode :MN1537 ;
      isa:hasOutputNode :DN1598 ;
      isa:hasStudy :S2 .

:MN1030
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.8" ;
      isa:hasInputNode :MN1465 ;
      isa:hasOutputNode :MN1977 ;
      isa:hasProtocolApplication
              :PA3950 ;
      isa:hasStudy :S2 .

:MN2136
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.39:out:0" ;
      isa:hasMaterial :M2559 ;
      isa:hasStudy :S2 .

:M2552
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:labelled_extract:a_microarray.NZ_1hrs_Drug_Sample_2_Labelled" .

:PA3938
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN1717
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.0:out:0" ;
      isa:hasMaterial :M3393 ;
      isa:hasStudy :S2 .

:M2339
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.N-0.1-aliquot5" .

:MN939
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.90" ;
      isa:hasInputNode :MN1883 ;
      isa:hasOutputNode :MN2105 ;
      isa:hasStudy :S2 .

:M2608
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:S-0.2-aliquot8" .

:M2712
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3933" .

:DPN474
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.80" ;
      isa:hasInputNode :DN1662 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:PA2977
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN1622
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.61:out:0" ;
      isa:hasMaterial :M3101 ;
      isa:hasStudy :S2 .

:MN216
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.8" ;
      isa:hasInputNode :MN2022 ;
      isa:hasOutputNode :MN1500 ;
      isa:hasStudy :S2 .

:M2609
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.S-0.2-aliquot8" .

:OE3204
      a       isa:OntologyEntry .

:A1278
      a       isa:Assay .

:MN1361
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.97:out:0" ;
      isa:hasMaterial :M3441 ;
      isa:hasStudy :S2 .

:DAN441
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.5" ;
      isa:hasInputNode :MN1380 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:DAN666
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.13" ;
      isa:hasInputNode :MN1322 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:PA3392
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN2137
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.23:out:0" ;
      isa:hasMaterial :M3419 ;
      isa:hasStudy :S2 .

:D3184
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC56_Carbon_0.07_External_2_1.txt" ;
      dcterms:title "JIC56_Carbon_0.07_External_2_1.txt" .

:MN944
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.85" ;
      isa:hasInputNode :MN2009 ;
      isa:hasOutputNode :MN1889 ;
      isa:hasStudy :S2 .

:MN2139
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.7:out:0" ;
      isa:hasMaterial :M2581 ;
      isa:hasStudy :S2 .

:D3244
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_derived_data:a_proteome.datatransformation3" ;
      isa:hasFactorValue :FV3246 , :FV3247 ;
      dcterms:title "datatransformation3" .

:MN1367
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.95:in:0" ;
      isa:hasMaterial :M3943 ;
      isa:hasStudy :S2 .

:DN1900
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.11:out:0" ;
      isa:hasData :D3551 ;
      isa:hasStudy :S2 .

:MN1695
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.105:out:0" ;
      isa:hasMaterial :M2917 ;
      isa:hasStudy :S2 .

:PA3398
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN1612
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.36:out:0" ;
      isa:hasMaterial :M2568 ;
      isa:hasStudy :S2 .

:MN679
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.15" ;
      isa:hasInputNode :MN1460 ;
      isa:hasOutputNode :MN1844 ;
      isa:hasStudy :S2 .

:MN218
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.83" ;
      isa:hasInputNode :MN2147 ;
      isa:hasOutputNode :MN2091 ;
      isa:hasProtocolApplication
              :PA2819 ;
      isa:hasStudy :S2 .

:DPN254
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.12" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1323 ;
      isa:hasStudy :S2 .

:MN1613
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.7:out:0" ;
      isa:hasMaterial :M3505 ;
      isa:hasStudy :S2 .

:FV3642
      a       isa:FactorValue .

:MN32
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.41" ;
      isa:hasInputNode :MN1769 ;
      isa:hasOutputNode :MN2102 ;
      isa:hasProtocolApplication
              :PA2307 ;
      isa:hasStudy :S2 .

:PA3936
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:FV3272
      a       isa:FactorValue .

:OE3522
      a       isa:OntologyEntry .

:DPN313
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.15" ;
      isa:hasInputNode :DN1730 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:PA2423
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1110 .

:MN945
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.84" ;
      isa:hasInputNode :MN1508 ;
      isa:hasOutputNode :MN2222 ;
      isa:hasStudy :S2 .

:MN2138
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.42:out:0" ;
      isa:hasMaterial :M3205 ;
      isa:hasStudy :S2 .

:D2697
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_normalized_data:a_proteome.norm2" ;
      isa:hasFactorValue :FV2700 , :FV2699 ;
      dcterms:title "norm2" .

:MN1696
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.135:out:0" ;
      isa:hasMaterial :M2984 ;
      isa:hasStudy :S2 .

isa:hasData
      a       owl:FunctionalProperty , owl:ObjectProperty ;
      rdfs:domain isa:DataNode ;
      rdfs:range isa:Data .

:DPN253
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.11" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1585 ;
      isa:hasStudy :S2 .

:MN1611
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.139:out:0" ;
      isa:hasMaterial :M2952 ;
      isa:hasStudy :S2 .

:MN1366
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.25:out:0" ;
      isa:hasMaterial :M2728 ;
      isa:hasStudy :S2 .

:MN217
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.84" ;
      isa:hasInputNode :MN1813 ;
      isa:hasOutputNode :MN1508 ;
      isa:hasProtocolApplication
              :PA2817 ;
      isa:hasStudy :S2 .

:DN1520
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.28:out:0" ;
      isa:hasData :D3720 ;
      isa:hasStudy :S2 .

:FV3643
      a       isa:FactorValue .

:DN1372
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.34:out:0" ;
      isa:hasData :D3382 ;
      isa:hasStudy :S2 .

:FV3579
      a       isa:FactorValue .

isa:hasParameterValue
      a       owl:ObjectProperty ;
      rdfs:domain isa:ProtocolApplication ;
      rdfs:range isa:ParameterValue .

:PA3935
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN946
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.80" ;
      isa:hasInputNode :MN1997 ;
      isa:hasOutputNode :MN1825 ;
      isa:hasStudy :S2 .

:FV3273
      a       isa:FactorValue .

:MN31
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.42" ;
      isa:hasInputNode :MN1983 ;
      isa:hasOutputNode :MN2050 ;
      isa:hasProtocolApplication
              :PA2304 ;
      isa:hasStudy :S2 .

:DPN466
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.76" ;
      isa:hasInputNode :DN1401 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:PA2420
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1109 .

:M3389
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.07-aliquot3" .

:PA3396
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:D3581
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3951" ;
      isa:hasFactorValue :FV3583 , :FV3584 ;
      dcterms:title "SCAN:MEXP:3951" .

:M3003
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC100_GlucoseO2_0.07_External_1_1" .

:MN1697
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.34:out:0" ;
      isa:hasMaterial :M2561 ;
      isa:hasStudy :S2 .

:DPN252
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.14" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1323 ;
      isa:hasStudy :S2 .

:MN1365
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.62:out:0" ;
      isa:hasMaterial :M3858 ;
      isa:hasStudy :S2 .

:MN677
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.24" ;
      isa:hasInputNode :MN1360 ;
      isa:hasOutputNode :MN2031 ;
      isa:hasProtocolApplication
              :PA3626 ;
      isa:hasStudy :S2 .

:M3943
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:source:culture9" .

:M2347
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.2-aliquot5" .

:DN1371
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.17:out:0" ;
      isa:hasData :D3652 ;
      isa:hasStudy :S2 .

:MN1615
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.27:out:0" ;
      isa:hasMaterial :M2481 ;
      isa:hasStudy :S2 .

:PA3969
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:OE2891
      a       isa:OntologyEntry .

:MN947
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.81" ;
      isa:hasInputNode :MN1359 ;
      isa:hasOutputNode :MN1824 ;
      isa:hasStudy :S2 .

:PA3934
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DPN315
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.16" ;
      isa:hasInputNode :DN1829 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:PA3933
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:PA2369
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN219
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.82" ;
      isa:hasInputNode :MN1563 ;
      isa:hasOutputNode :MN2026 ;
      isa:hasProtocolApplication
              :PA2821 ;
      isa:hasStudy :S2 .

:DPN251
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.13" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1323 ;
      isa:hasStudy :S2 .

:MN1029
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.90" ;
      isa:hasInputNode :MN1367 ;
      isa:hasOutputNode :MN1902 ;
      isa:hasProtocolApplication
              :PA3949 ;
      isa:hasStudy :S2 .

:MN1364
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.38:out:0" ;
      isa:hasMaterial :M2555 ;
      isa:hasStudy :S2 .

isa:Protocol
      rdfs:subClassOf isa:Accessible .

:DN1370
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.58:out:0" ;
      isa:hasData :D3127 ;
      isa:hasStudy :S2 .

:OE3147
      a       isa:OntologyEntry .

:MN1614
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.79:out:0" ;
      isa:hasMaterial :M2800 ;
      isa:hasStudy :S2 .

:M2348
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.N-0.2-aliquot5" .

:D2618
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3913" ;
      dcterms:title "SCAN:MEXP:3913" .

:DN2084
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.86:out:0" ;
      isa:hasData :D2989 ;
      isa:hasStudy :S2 .

:OE3520
      a       isa:OntologyEntry .

:MN948
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.82" ;
      isa:hasInputNode :MN2026 ;
      isa:hasOutputNode :MN1627 ;
      isa:hasStudy :S2 .

:MN1039
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.2" ;
      isa:hasInputNode :MN1465 ;
      isa:hasOutputNode :MN1504 ;
      isa:hasProtocolApplication
              :PA3959 ;
      isa:hasStudy :S2 .

:D2966
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_derived_data:a_metabolome.foo_ds" ;
      isa:hasFactorValue :FV2969 , :FV2968 ;
      dcterms:title "foo_ds" .

:MN1028
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.9" ;
      isa:hasInputNode :MN1465 ;
      isa:hasOutputNode :MN1966 ;
      isa:hasProtocolApplication
              :PA3948 ;
      isa:hasStudy :S2 .

:DN1955
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.93:out:0" ;
      isa:hasData :D3073 ;
      isa:hasStudy :S2 .

:M3238
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC12_Nitrogen_0.07_Internal_3_1" .

:MN940
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.89" ;
      isa:hasInputNode :MN2211 ;
      isa:hasOutputNode :MN1810 ;
      isa:hasStudy :S2 .

:DPN258
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.16" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1323 ;
      isa:hasStudy :S2 .

:PA2426
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1110 .

:PA3932
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:PA3967
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:M2799
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:G-0.1-aliquot4" .

:M2345
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.N-0.1-aliquot7" .

:MN1617
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.47:out:0" ;
      isa:hasMaterial :M2276 ;
      isa:hasStudy :S2 .

isa:hasParameter
      a       owl:ObjectProperty ;
      rdfs:domain isa:ParameterValue ;
      rdfs:range isa:Parameter .

:MN36
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.37" ;
      isa:hasInputNode :MN2130 ;
      isa:hasOutputNode :MN1944 ;
      isa:hasProtocolApplication
              :PA2319 ;
      isa:hasStudy :S2 .

:D3189
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC59_Carbon_0.10_External_2_1.txt" ;
      dcterms:title "JIC59_Carbon_0.10_External_2_1.txt" .

:PA2363
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M3239
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC1_Carbon_0.07_Internal_1_1" .

:MN1027
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.0" ;
      isa:hasInputNode :MN1473 ;
      isa:hasOutputNode :MN1985 ;
      isa:hasStudy :S2 .

:DAN348
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.89" ;
      isa:hasInputNode :MN1533 ;
      isa:hasOutputNode :DN2071 ;
      isa:hasStudy :S2 .

:MN941
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.88" ;
      isa:hasInputNode :MN2044 ;
      isa:hasOutputNode :MN2125 ;
      isa:hasStudy :S2 .

:DPN257
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.15" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1323 ;
      isa:hasStudy :S2 .

:D2612
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3910" ;
      dcterms:title "SCAN:MEXP:3910" .

:OE3526
      a       isa:OntologyEntry .

:MN1692
      a       isa:MaterialNode ;
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      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

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      a       isa:DataNode ;
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      isa:hasData :D3102 ;
      isa:hasStudy :S2 .

:PA2577
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2545
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:extract:a_microarray.NZ_2hrs_Vehicle_Sample_2_Extract" .

:PA3968
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:RS1101
      a       isa:ReferenceSources ;
      isa:hasAccessionID "BTO" ;
      dcterms:description "BRENDA tissue / enzyme source" ;
      dcterms:hasVersion "v 1.26" ;
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:MN1616
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.2:out:0" ;
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      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1862 ;
      isa:hasProtocolApplication
              :PA2316 ;
      isa:hasStudy :S2 .

:M2233
      a       isa:Material ;
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:MN1026
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.6" ;
      isa:hasInputNode :MN1465 ;
      isa:hasOutputNode :MN2056 ;
      isa:hasProtocolApplication
              :PA3947 ;
      isa:hasStudy :S2 .

:D3585
      a       isa:Data ;
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      isa:hasFactorValue :FV3588 , :FV3587 ;
      dcterms:title "SCAN:MEXP:3949" .

:D3029
      a       isa:Data ;
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      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN2169 ;
      isa:hasProtocolApplication
              :PA3957 ;
      isa:hasStudy :S2 .

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      a       isa:MaterialNode ;
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      isa:hasMaterial :M3239 ;
      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1710 ;
      isa:hasOutputNode :MN1656 ;
      isa:hasStudy :S2 .

:PA2366
      a       isa:ProtocolApplication ;
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:D3186
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC1_Carbon_0.07_Internal_1_3.txt" ;
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:PA3930
      a       isa:ProtocolApplication ;
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:PA3965
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

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      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

isa:Design
      rdfs:subClassOf isa:FreeTextTerm .

:M3084
      a       isa:Material ;
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:RS1100
      a       isa:ReferenceSources ;
      isa:hasAccessionID "CHEBI" ;
      dcterms:description "Chemical Entities of Biological Interest" ;
      dcterms:hasVersion "v 1.26" ;
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:FV3274
      a       isa:FactorValue .

:M2230
      a       isa:Material ;
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:MN1619
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.17:out:0" ;
      isa:hasMaterial :M2373 ;
      isa:hasStudy :S2 .

:M2548
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:hybridization:a_microarray.NZ_4hrs_Drug_Sample_2_Labelled_Hyb12" .

:MN34
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1758 ;
      isa:hasProtocolApplication
              :PA2313 ;
      isa:hasStudy :S2 .

:MN1038
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.96" ;
      isa:hasInputNode :MN1445 ;
      isa:hasOutputNode :MN1904 ;
      isa:hasProtocolApplication
              :PA3958 ;
      isa:hasStudy :S2 .

:D3646
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3925" ;
      isa:hasFactorValue :FV3649 , :FV3648 ;
      dcterms:title "SCAN:MEXP:3925" .

:MN1694
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.12:out:0" ;
      isa:hasMaterial :M2514 ;
      isa:hasStudy :S2 .

:DN1488
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.17:out:0" ;
      isa:hasData :D3006 ;
      isa:hasStudy :S2 .

:MN1025
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.92" ;
      isa:hasInputNode :MN1367 ;
      isa:hasOutputNode :MN1433 ;
      isa:hasProtocolApplication
              :PA3946 ;
      isa:hasStudy :S2 .

:MN943
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN2009 ;
      isa:hasOutputNode :MN1889 ;
      isa:hasStudy :S2 .

:DPN469
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.79" ;
      isa:hasInputNode :DN1864 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:D3370
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3949" ;
      dcterms:title "SCAN:MEXP:3949" .

:DPN311
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.14" ;
      isa:hasInputNode :DN2217 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DPN255
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.17" ;
      isa:hasInputNode :DN1358 ;
      isa:hasOutputNode :DN1323 ;
      isa:hasStudy :S2 .

:OE3524
      a       isa:OntologyEntry .

:PA3966
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN830
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.61" ;
      isa:hasInputNode :MN1768 ;
      isa:hasOutputNode :MN1622 ;
      isa:hasStudy :S2 .

:D2614
      a       isa:Data ;
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      isa:hasFactorValue :FV2617 , :FV2616 ;
      dcterms:title "SCAN:MEXP:3910" .

:M2547
      a       isa:Material ;
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:MN1618
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2685 ;
      isa:hasStudy :S2 .

:M2231
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.P-0.2-aliquot6" .

:MN33
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN2046 ;
      isa:hasOutputNode :MN2208 ;
      isa:hasProtocolApplication
              :PA2310 ;
      isa:hasStudy :S2 .

:M2344
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.1-aliquot7" .

:M2236
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.07-aliquot5" .

:M2437
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.C-0.2-aliquot4" .

:M2341
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.1-aliquot6" .

:MN1508
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.84:out:0" ;
      isa:hasMaterial :M2818 ;
      isa:hasStudy :S2 .

:PA3963
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN795
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.42" ;
      isa:hasInputNode :MN1336 ;
      isa:hasOutputNode :MN1992 ;
      isa:hasProtocolApplication
              :PA3814 ;
      isa:hasStudy :S2 .

:MN152
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1617 ;
      isa:hasOutputNode :MN1930 ;
      isa:hasProtocolApplication
              :PA2680 ;
      isa:hasStudy :S2 .

:D3853
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC94_Ethanol_0.10_External_1_1.txt" ;
      dcterms:title "JIC94_Ethanol_0.10_External_1_1.txt" .

:MN831
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.60" ;
      isa:hasInputNode :MN1463 ;
      isa:hasOutputNode :MN1354 ;
      isa:hasStudy :S2 .

:M3234
      a       isa:Material ;
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:PA2360
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:DAN345
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN1855 ;
      isa:hasOutputNode :DN1726 ;
      isa:hasStudy :S2 .

:DPN699
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.21" ;
      isa:hasInputNode :DN1602 ;
      isa:hasOutputNode :DN1890 ;
      isa:hasStudy :S2 .

:M2237
      a       isa:Material ;
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:M2342
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.N-0.1-aliquot6" .

:M2436
      a       isa:Material ;
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:PA3964
      a       isa:ProtocolApplication ;
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:OE3635
      a       isa:OntologyEntry .

:DN1952
      a       isa:DataNode ;
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      isa:hasData :D3203 ;
      isa:hasStudy :S2 .

:M3235
      a       isa:Material ;
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:MN832
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1922 ;
      isa:hasOutputNode :MN1471 ;
      isa:hasStudy :S2 .

:MN153
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN2050 ;
      isa:hasOutputNode :MN1947 ;
      isa:hasProtocolApplication
              :PA2682 ;
      isa:hasStudy :S2 .

:M3008
      a       isa:Material ;
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:MN1583
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.0:out:0" ;
      isa:hasMaterial :M2389 ;
      isa:hasStudy :S1 .

:M2439
      a       isa:Material ;
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:M2234
      a       isa:Material ;
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:MN154
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN2102 ;
      isa:hasOutputNode :MN1618 ;
      isa:hasProtocolApplication
              :PA2684 ;
      isa:hasStudy :S2 .

:MN833
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1391 ;
      isa:hasOutputNode :MN2092 ;
      isa:hasProtocolApplication
              :PA3862 ;
      isa:hasStudy :S2 .

:PA3961
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:D3855
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC93_Ethanol_0.07_External_3_1.txt" ;
      dcterms:title "JIC93_Ethanol_0.07_External_3_1.txt" .

:M3236
      a       isa:Material ;
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:FV2606
      a       isa:FactorValue .

:MN797
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1567 ;
      isa:hasOutputNode :MN1400 ;
      isa:hasProtocolApplication
              :PA3816 ;
      isa:hasStudy :S2 .

:MN2065
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.94:out:0" ;
      isa:hasMaterial :M2516 ;
      isa:hasStudy :S2 .

:D3694
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3931" ;
      isa:hasFactorValue :FV3696 , :FV3697 ;
      dcterms:title "SCAN:MEXP:3931" .

:DAN343
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.93" ;
      isa:hasInputNode :MN1754 ;
      isa:hasOutputNode :DN1955 ;
      isa:hasStudy :S2 .

:MN1478
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.24:out:0" ;
      isa:hasMaterial :M2495 ;
      isa:hasStudy :S2 .

:DN1412
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.9:out:0" ;
      isa:hasData :D3326 ;
      isa:hasStudy :S1 .

:D3589
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3950" ;
      isa:hasFactorValue :FV3591 , :FV3592 ;
      dcterms:title "SCAN:MEXP:3950" .

:MN1584
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.93:out:0" ;
      isa:hasMaterial :M2519 ;
      isa:hasStudy :S2 .

:DN2118
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.31:out:0" ;
      isa:hasData :D3537 ;
      isa:hasStudy :S2 .

:M2828
      a       isa:Material ;
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:MN1509
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.82:in:0" ;
      isa:hasMaterial :M3923 ;
      isa:hasStudy :S2 .

:FV3279
      a       isa:FactorValue .

:M2945
      a       isa:Material ;
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:PA2429
      a       isa:ProtocolApplication ;
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:MN834
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1841 ;
      isa:hasStudy :S2 .

:PA3962
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN155
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN2060 ;
      isa:hasOutputNode :MN1819 ;
      isa:hasProtocolApplication
              :PA2686 ;
      isa:hasStudy :S2 .

isa:OntologyTerm
      rdfs:subClassOf isa:OntologyEntry .

:M3237
      a       isa:Material ;
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:M3089
      a       isa:Material ;
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:MN796
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1567 ;
      isa:hasOutputNode :MN2188 ;
      isa:hasProtocolApplication
              :PA3815 ;
      isa:hasStudy :S2 .

:D3026
      a       isa:Data ;
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:MN2066
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2677 ;
      isa:hasStudy :S2 .

:PA2298
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:DN1379
      a       isa:DataNode ;
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      isa:hasData :D2966 ;
      isa:hasStudy :S2 .

:PA3449
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:M2829
      a       isa:Material ;
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:MN1477
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2367 ;
      isa:hasStudy :S2 .

:MN836
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1391 ;
      isa:hasOutputNode :MN1624 ;
      isa:hasProtocolApplication
              :PA3865 ;
      isa:hasStudy :S2 .

:M3945
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:source:culture1" .

:MN1504
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.2:out:0" ;
      isa:hasMaterial :M3389 ;
      isa:hasStudy :S2 .

:MN1586
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.19:out:0" ;
      isa:hasMaterial :M3256 ;
      isa:hasStudy :S2 .

:MN2063
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.22:out:0" ;
      isa:hasMaterial :M2471 ;
      isa:hasStudy :S2 .

:DN1483
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.52:out:0" ;
      isa:hasData :D3196 ;
      isa:hasStudy :S2 .

:MN835
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.121" ;
      isa:hasInputNode :MN1391 ;
      isa:hasOutputNode :MN1342 ;
      isa:hasProtocolApplication
              :PA3864 ;
      isa:hasStudy :S2 .

:DAN341
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN2052 ;
      isa:hasOutputNode :DN1490 ;
      isa:hasStudy :S2 .

:MN156
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.43" ;
      isa:hasInputNode :MN1833 ;
      isa:hasOutputNode :MN1494 ;
      isa:hasProtocolApplication
              :PA2688 ;
      isa:hasStudy :S2 .

:MN837
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.123" ;
      isa:hasInputNode :MN1391 ;
      isa:hasOutputNode :MN1608 ;
      isa:hasProtocolApplication
              :PA3866 ;
      isa:hasStudy :S2 .

:DPN695
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.19" ;
      isa:hasInputNode :DN1555 ;
      isa:hasOutputNode :DN2168 ;
      isa:hasStudy :S2 .

:D3531
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3953" ;
      isa:hasFactorValue :FV3534 , :FV3533 ;
      dcterms:title "SCAN:MEXP:3953" .

:MN790
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.45" ;
      isa:hasInputNode :MN1336 ;
      isa:hasOutputNode :MN2025 ;
      isa:hasProtocolApplication
              :PA3803 ;
      isa:hasStudy :S2 .

:MN157
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.161" ;
      isa:hasInputNode :MN1411 ;
      isa:hasOutputNode :MN1563 ;
      isa:hasProtocolApplication
              :PA2690 ;
      isa:hasStudy :S2 .

:MN1475
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.28:out:0" ;
      isa:hasMaterial :M2714 ;
      isa:hasStudy :S2 .

:MN1502
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.29:out:0" ;
      isa:hasMaterial :M2477 ;
      isa:hasStudy :S2 .

:MN2064
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.9:out:0" ;
      isa:hasMaterial :M2548 ;
      isa:hasStudy :S1 .

:D3024
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC73_Phosphate_0.07_External_1_3.txt" ;
      dcterms:title "JIC73_Phosphate_0.07_External_1_3.txt" .

:MN1587
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.16:out:0" ;
      isa:hasMaterial :M3625 ;
      isa:hasStudy :S2 .

:M3157
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC62_Carbon_0.20_External_2_1" .

:FV2605
      a       isa:FactorValue .

:D3181
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC57_Carbon_0.07_External_3_1.txt" ;
      dcterms:title "JIC57_Carbon_0.07_External_3_1.txt" .

:DAN340
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.91" ;
      isa:hasInputNode :MN1951 ;
      isa:hasOutputNode :DN1472 ;
      isa:hasStudy :S2 .

:DPN317
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.17" ;
      isa:hasInputNode :DN1488 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

isa:hasProtocol
      a       owl:ObjectProperty ;
      rdfs:domain isa:Study ;
      rdfs:range isa:Protocol .

:PA3960
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN838
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.64" ;
      isa:hasInputNode :MN1798 ;
      isa:hasOutputNode :MN1969 ;
      isa:hasStudy :S2 .

:FV3648
      a       isa:FactorValue .

:MN1506
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.43:out:0" ;
      isa:hasMaterial :M3202 ;
      isa:hasStudy :S2 .

:MN568
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.11" ;
      isa:hasInputNode :MN1994 ;
      isa:hasOutputNode :MN1766 ;
      isa:hasProtocolApplication
              :PA3430 ;
      isa:hasStudy :S1 .

:MN793
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.43" ;
      isa:hasInputNode :MN1336 ;
      isa:hasOutputNode :MN1443 ;
      isa:hasProtocolApplication
              :PA3809 ;
      isa:hasStudy :S2 .

:MN158
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.162" ;
      isa:hasInputNode :MN1411 ;
      isa:hasOutputNode :MN2147 ;
      isa:hasProtocolApplication
              :PA2693 ;
      isa:hasStudy :S2 .

:PA3674
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN2061
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.16:out:0" ;
      isa:hasMaterial :M2846 ;
      isa:hasStudy :S2 .

:M3232
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC17_Nitrogen_0.20_Internal_2_1" .

:D3851
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC95_Ethanol_0.10_External_2_1.txt" ;
      dcterms:title "JIC95_Ethanol_0.10_External_2_1.txt" .

:PA2295
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:M2239
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.1-aliquot5" .

:MN839
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.124" ;
      isa:hasInputNode :MN1391 ;
      isa:hasOutputNode :MN2053 ;
      isa:hasProtocolApplication
              :PA3867 ;
      isa:hasStudy :S2 .

:DPN319
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.18" ;
      isa:hasInputNode :DN1579 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DPN697
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.20" ;
      isa:hasInputNode :DN1913 ;
      isa:hasOutputNode :DN1802 ;
      isa:hasStudy :S2 .

:MN1505
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.34:out:0" ;
      isa:hasMaterial :M2775 ;
      isa:hasStudy :S2 .

:MN1589
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.71:out:0" ;
      isa:hasMaterial :M3154 ;
      isa:hasStudy :S2 .

:MN1473
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.0:out:0" ;
      isa:hasMaterial :M2898 ;
      isa:hasStudy :S2 .

:MN792
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.44" ;
      isa:hasInputNode :MN1336 ;
      isa:hasOutputNode :MN1870 ;
      isa:hasProtocolApplication
              :PA3808 ;
      isa:hasStudy :S2 .

:FV3649
      a       isa:FactorValue .

:MN159
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.160" ;
      isa:hasInputNode :MN1411 ;
      isa:hasOutputNode :MN1413 ;
      isa:hasProtocolApplication
              :PA2695 ;
      isa:hasStudy :S2 .

:M3233
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC15_Nitrogen_0.10_Internal_3_1" .

:D3022
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC51_GlucoseO2_0.10_Internal_3_1.txt" ;
      dcterms:title "JIC51_GlucoseO2_0.10_Internal_3_1.txt" .

:M3454
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.2-aliquot3" .

:M2836
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_proteome.JC_S-0.1" .

:PA2853
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:OE3171
      a       isa:OntologyEntry .

:MN1925
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.34:out:0" ;
      isa:hasMaterial :M3415 ;
      isa:hasStudy :S2 .

:DAN439
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.7" ;
      isa:hasInputNode :MN1500 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:DAN708
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.2" ;
      isa:hasInputNode :MN1394 ;
      isa:hasOutputNode :DN1390 ;
      isa:hasStudy :S1 .

:M2434
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.C-0.2-aliquot3" .

:MN764
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.40" ;
      isa:hasInputNode :MN2007 ;
      isa:hasOutputNode :MN2178 ;
      isa:hasStudy :S2 .

:DPN501
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.90" ;
      isa:hasInputNode :DN1984 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DPN368
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.45" ;
      isa:hasInputNode :DN1407 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN175
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.21" ;
      isa:hasInputNode :MN1871 ;
      isa:hasOutputNode :MN2172 ;
      isa:hasProtocolApplication
              :PA2719 ;
      isa:hasStudy :S2 .

:MN1424
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.99:out:0" ;
      isa:hasMaterial :M2874 ;
      isa:hasStudy :S2 .

:MN1780
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.76:out:0" ;
      isa:hasMaterial :M3177 ;
      isa:hasStudy :S2 .

:A1130
      a       isa:Assay .

:PA3445
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:M2837
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_proteome.JC_C-0.1" .

:M3704
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.2-aliquot5" .

:MN1926
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.147:out:0" ;
      isa:hasMaterial :M2831 ;
      isa:hasStudy :S2 .

:FV3320
      a       isa:FactorValue .

:M3857
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.C-0.07-aliquot5" .

:DPN690
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.17" ;
      isa:hasInputNode :DN2015 ;
      isa:hasOutputNode :DN1371 ;
      isa:hasStudy :S2 .

:PA3751
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN765
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.50" ;
      isa:hasInputNode :MN1336 ;
      isa:hasOutputNode :MN2198 ;
      isa:hasProtocolApplication
              :PA3776 ;
      isa:hasStudy :S2 .

:MN174
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.20" ;
      isa:hasInputNode :MN1799 ;
      isa:hasOutputNode :MN2036 ;
      isa:hasProtocolApplication
              :PA2717 ;
      isa:hasStudy :S2 .

:DAN437
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.53" ;
      isa:hasInputNode :MN1643 ;
      isa:hasOutputNode :DN1593 ;
      isa:hasStudy :S2 .

:DPN500
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.1" ;
      isa:hasInputNode :DN2095 ;
      isa:hasOutputNode :DN1610 ;
      isa:hasStudy :S1 .

:MN1423
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.68:out:0" ;
      isa:hasMaterial :M2751 ;
      isa:hasStudy :S2 .

:DN1420
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.60:out:0" ;
      isa:hasData :D3099 ;
      isa:hasStudy :S2 .

:PA2928
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1102 .

:OE3020
      a       isa:OntologyEntry .

:M3452
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.2-aliquot4" .

:PA2855
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN2080
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.4:out:0" ;
      isa:hasMaterial :M3508 ;
      isa:hasStudy :S2 .

:M2410
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_proteome.N-0.1" .

:MN1923
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.130:out:0" ;
      isa:hasMaterial :M2873 ;
      isa:hasStudy :S2 .

:FV3321
      a       isa:FactorValue .

:M3858
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.C-0.2-aliquot10" .

:M2611
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3914" .

:MN551
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.13" ;
      isa:hasInputNode :MN1839 ;
      isa:hasOutputNode :MN1553 ;
      isa:hasProtocolApplication
              :PA3408 ;
      isa:hasStudy :S2 .

isa:Parameter
      rdfs:subClassOf isa:Property .

:MN1060
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.23" ;
      isa:hasInputNode :MN1350 ;
      isa:hasOutputNode :MN1353 ;
      isa:hasStudy :S2 .

:PA3754
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DAN436
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.5.6.6" ;
      isa:hasInputNode :MN1500 ;
      isa:hasOutputNode :DN1358 ;
      isa:hasStudy :S2 .

:MN762
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.56" ;
      isa:hasInputNode :MN1357 ;
      isa:hasOutputNode :MN1329 ;
      isa:hasProtocolApplication
              :PA3773 ;
      isa:hasStudy :S2 .

:MN1782
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.2:out:0" ;
      isa:hasMaterial :M2896 ;
      isa:hasStudy :S2 .

:MN173
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.29" ;
      isa:hasInputNode :MN1962 ;
      isa:hasOutputNode :MN1827 ;
      isa:hasProtocolApplication
              :PA2715 ;
      isa:hasStudy :S2 .

:A1132
      a       isa:Assay .

:PA3447
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:MN1422
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.56:out:0" ;
      isa:hasMaterial :M3136 ;
      isa:hasStudy :S2 .

:MN740
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.20" ;
      isa:hasInputNode :MN1339 ;
      isa:hasOutputNode :MN2129 ;
      isa:hasProtocolApplication
              :PA3749 ;
      isa:hasStudy :S2 .

:OE3174
      a       isa:OntologyEntry .

:M2839
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:G-0.1-aliquot1" .

:FV3322
      a       isa:FactorValue .

:OE3210
      a       isa:OntologyEntry .

:M3859
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.C-0.2-aliquot9" .

:DAN709
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.1" ;
      isa:hasInputNode :MN1689 ;
      isa:hasOutputNode :DN2095 ;
      isa:hasStudy :S1 .

:M2433
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.C-0.2-aliquot3" .

:MN550
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.7" ;
      isa:hasInputNode :MN2154 ;
      isa:hasOutputNode :MN1600 ;
      isa:hasProtocolApplication
              :PA3406 ;
      isa:hasStudy :S2 .

:PA3753
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN763
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.55" ;
      isa:hasInputNode :MN1357 ;
      isa:hasOutputNode :MN1351 ;
      isa:hasProtocolApplication
              :PA3774 ;
      isa:hasStudy :S2 .

:MN172
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.28" ;
      isa:hasInputNode :MN1939 ;
      isa:hasOutputNode :MN1475 ;
      isa:hasProtocolApplication
              :PA2713 ;
      isa:hasStudy :S2 .

:MN1421
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.134:out:0" ;
      isa:hasMaterial :M2981 ;
      isa:hasStudy :S2 .

:PA2926
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1102 .

:A1131
      a       isa:Assay .

:MN741
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.39" ;
      isa:hasInputNode :MN1654 ;
      isa:hasOutputNode :MN1774 ;
      isa:hasStudy :S2 .

:PA3816
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN1702
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.32:out:0" ;
      isa:hasMaterial :M2531 ;
      isa:hasStudy :S2 .

:M3241
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC1_Carbon_0.07_Internal_1_3" .

:MN819
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.53" ;
      isa:hasInputNode :MN1387 ;
      isa:hasOutputNode :MN1643 ;
      isa:hasStudy :S2 .

:DPN505
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.5" ;
      isa:hasInputNode :DN1570 ;
      isa:hasOutputNode :DN1676 ;
      isa:hasStudy :S1 .

:M2430
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:labelled_extract:a_microarray.NZ_2hrs_Drug_Sample_2_Labelled" .

:M2832
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.G-0.07-aliquot2" .

:OE3213
      a       isa:OntologyEntry .

:M3878
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.G-0.07-aliquot4" .

:M2288
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.C-0.2-aliquot1" .

:MN1929
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.93:out:0" ;
      isa:hasMaterial :M3916 ;
      isa:hasStudy :S2 .

:MN1429
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.4:out:0" ;
      isa:hasMaterial :M2636 ;
      isa:hasStudy :S2 .

:PA2857
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:M3450
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.2-aliquot1" .

:MN2082
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.25:out:0" ;
      isa:hasMaterial :M2787 ;
      isa:hasStudy :S2 .

:DN1585
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.6.7.6:out:0" ;
      isa:hasData :D2697 ;
      isa:hasStudy :S2 .

:MN742
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.119" ;
      isa:hasInputNode :MN1391 ;
      isa:hasOutputNode :MN2155 ;
      isa:hasProtocolApplication
              :PA3751 ;
      isa:hasStudy :S2 .

:MN553
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.15" ;
      isa:hasInputNode :MN2089 ;
      isa:hasOutputNode :MN1484 ;
      isa:hasProtocolApplication
              :PA3412 ;
      isa:hasStudy :S2 .

:D3358
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3952" ;
      dcterms:title "SCAN:MEXP:3952" .

:MN171
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.27" ;
      isa:hasInputNode :MN1615 ;
      isa:hasOutputNode :MN1663 ;
      isa:hasProtocolApplication
              :PA2711 ;
      isa:hasStudy :S2 .

:MN1062
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.4.5.12" ;
      isa:hasInputNode :MN1392 ;
      isa:hasOutputNode :MN1322 ;
      isa:hasStudy :S2 .

:A1134
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      a       isa:ProtocolApplication ;
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      a       isa:FactorValue .

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      a       isa:Data ;
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:DN2146
      a       isa:DataNode ;
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      isa:hasStudy :S2 .

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      a       isa:DataAcquisition ;
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      isa:hasStudy :S2 .

:A1234
      a       isa:Assay .

:DAN884
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN1749 ;
      isa:hasOutputNode :DN1562 ;
      isa:hasStudy :S1 .

:MN65
      a       isa:MaterialProcessing ;
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      isa:hasProtocolApplication
              :PA2405 ;
      isa:hasStudy :S2 .

isa:CharacteristicValue
      rdfs:subClassOf isa:PropertyValue .

:MN1626
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2279 ;
      isa:hasStudy :S2 .

:D3104
      a       isa:Data ;
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      a       isa:MaterialProcessing ;
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              :PA2798 ;
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      a       isa:FactorValue .

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      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:OE2656
      a       isa:OntologyEntry .

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      isa:hasStudy :S2 .

:M3038
      a       isa:Material ;
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      a       isa:MaterialNode ;
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      isa:hasMaterial :M2236 ;
      isa:hasStudy :S2 .

:A1235
      a       isa:Assay .

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      a       isa:Data ;
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      isa:hasFactorValue :FV2606 , :FV2605 ;
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:PA3924
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:OE2881
      a       isa:OntologyEntry .

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      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

:MN68
      a       isa:MaterialProcessing ;
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      isa:hasProtocolApplication
              :PA2414 ;
      isa:hasStudy :S2 .

:FV3654
      a       isa:FactorValue .

:M2976
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.E-0.07-aliquot4" .

:DAN885
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.6" ;
      isa:hasInputNode :MN2175 ;
      isa:hasOutputNode :DN1821 ;
      isa:hasStudy :S1 .

:OE3367
      a       isa:OntologyEntry .

:MN1578
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.75:out:0" ;
      isa:hasMaterial :M3478 ;
      isa:hasStudy :S2 .

:MN206
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.72" ;
      isa:hasInputNode :MN1648 ;
      isa:hasOutputNode :MN1609 ;
      isa:hasProtocolApplication
              :PA2795 ;
      isa:hasStudy :S2 .

:DAN803
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.106" ;
      isa:hasInputNode :MN1426 ;
      isa:hasOutputNode :DN2020 ;
      isa:hasStudy :S2 .

:S1   a       isa:Study ;
      isa:hasAccessionID "BII-S-2" ;
      isa:hasAssay :A1127 , :A1184 , :A1124 , :A1214 , :A1165 , :A1185 , :A1298 , :A1251 , :A1238 , :A1269 , :A1220 , :A1282 , :A1233 , :A1136 ;
      isa:hasOwner :ISA_1113 , :ISA_3982 , :ISA_3981 ;
      isa:hasProtocol :P_1106 , :P_1108 , :P_1102 , :P_1110 ;
      dcterms:created "29 Apr 2007 20:00:00 GMT" ;
      dcterms:description "Comprehensive high-throughput analyses at the levels of mRNAs, proteins, and metabolites, and studies on gene expression patterns are required for systems biology studies of cell growth [4,26-29]. Although such comprehensive data sets are lacking, many studies have pointed to a central role for the target-of-rapamycin (TOR) signal transduction pathway in growth control. TOR is a serine/threonine kinase that has been conserved from yeasts to mammals; it integrates signals from nutrients or growth factors to regulate cell growth and cell-cycle progression coordinately. Although such comprehensive data sets are lacking, many studies have pointed to a central role for the target-of-rapamycin (TOR) signal transduction pathway in growth control. TOR is a serine/threonine kinase that has been conserved from yeasts to mammals; it integrates signals from nutrients or growth factors to regulate cell growth and cell-cycle progression coordinately. The effect of rapamycin were studied as follows: a culture growing at mid-exponential phase was divided into two. Rapamycin (200 ng/ml) was added to one half, and the drug's solvent to the other, as the control. Samples were taken at 0, 1, 2 and 4 h after treatment. Gene expression at the mRNA level was investigated by transcriptome analysis using Affymetrix hybridization arrays." ;
      dcterms:title "A time course analysis of  transcription response in yeast treated with rapamycin, a specific inhibitor of the TORC1 complex: impact on yeast growth" .

:MN1355
      a       isa:MaterialNode ;
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      isa:hasStudy :S1 .

:A1236
      a       isa:Assay .

:MN2103
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2243 ;
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:DN2148
      a       isa:DataNode ;
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      isa:hasData :D3730 ;
      isa:hasStudy :S2 .

:MN277
      a       isa:MaterialProcessing ;
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      isa:hasStudy :S2 .

:D3196
      a       isa:Data ;
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      a       isa:DataAcquisition ;
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      isa:hasStudy :S2 .

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:M2975
      a       isa:Material ;
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:FV3655
      a       isa:FactorValue .

:MN67
      a       isa:MaterialProcessing ;
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              :PA2411 ;
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:MN1624
      a       isa:MaterialNode ;
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      a       isa:DataNode ;
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      isa:hasData :D3585 ;
      isa:hasStudy :S2 .

:MN278
      a       isa:MaterialProcessing ;
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              :PA2920 ;
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:D3102
      a       isa:Data ;
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      a       isa:MaterialNode ;
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      a       isa:ProtocolApplication ;
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      a       isa:MaterialProcessing ;
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              :PA2792 ;
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      a       isa:DataProcessing ;
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      isa:hasOutputNode :DN1379 ;
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:MN2102
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2309 ;
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:OE2658
      a       isa:OntologyEntry .

:MN1860
      a       isa:MaterialNode ;
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      isa:hasMaterial :M3712 ;
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:D3099
      a       isa:Data ;
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:DN2099
      a       isa:DataNode ;
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      isa:hasStudy :S2 .

:A1237
      a       isa:Assay .

:PA2411
      a       isa:ProtocolApplication ;
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      a       isa:Material ;
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:D3094
      a       isa:Data ;
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:A1125
      a       isa:Assay .

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      a       isa:OntologyEntry .

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      a       isa:DataProcessing ;
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      a       isa:MaterialProcessing ;
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      a       isa:Data ;
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:MN556
      a       isa:MaterialProcessing ;
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      isa:hasOutputNode :MN1536 ;
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              :PA3418 ;
      isa:hasStudy :S2 .

:PA2920
      a       isa:ProtocolApplication ;
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:FV3246
      a       isa:FactorValue .

:M2285
      a       isa:Material ;
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:M3861
      a       isa:Material ;
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:M2978
      a       isa:Material ;
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:MN62
      a       isa:MaterialProcessing ;
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              :PA2396 ;
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:PA3970
      a       isa:ProtocolApplication ;
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:DAN350
      a       isa:DataAcquisition ;
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:OE3665
      a       isa:OntologyEntry .

:MN971
      a       isa:MaterialProcessing ;
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      isa:hasStudy :S2 .

:A1126
      a       isa:Assay .

:D3191
      a       isa:Data ;
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:DAN376
      a       isa:DataAcquisition ;
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:MN557
      a       isa:MaterialProcessing ;
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              :PA3420 ;
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:DPN372
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:PA3663
      a       isa:ProtocolApplication ;
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      a       isa:Material ;
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:PA2393
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1110 .

:FV3247
      a       isa:FactorValue .

:FV3315
      a       isa:FactorValue .

:M3860
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.C-0.2-aliquot8" .

:MN61
      a       isa:MaterialProcessing ;
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              :PA2393 ;
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:M2404
      a       isa:Material ;
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:M3886
      a       isa:Material ;
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:DAN375
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN1681 ;
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:D3096
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:M3242
      a       isa:Material ;
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:PA3971
      a       isa:ProtocolApplication ;
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:A1127
      a       isa:Assay .

:MN823
      a       isa:MaterialProcessing ;
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              :PA3849 ;
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      a       isa:Data ;
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:D3542
      a       isa:Data ;
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      a       isa:MaterialNode ;
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:DPN728
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:MN558
      a       isa:MaterialProcessing ;
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              :PA3422 ;
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:D3615
      a       isa:Data ;
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:M3863
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:DPN684
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:MN1418
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:PA3815
      a       isa:ProtocolApplication ;
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:M2407
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_proteome.C-0.1" .

:MN64
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.3" ;
      isa:hasInputNode :MN1314 ;
      isa:hasOutputNode :MN1866 ;
      isa:hasProtocolApplication
              :PA2402 ;
      isa:hasStudy :S1 .

:MN824
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.139" ;
      isa:hasInputNode :MN1431 ;
      isa:hasOutputNode :MN1611 ;
      isa:hasProtocolApplication
              :PA3850 ;
      isa:hasStudy :S2 .

:PA3972
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:A1128
      a       isa:Assay .

:M3243
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC71_Nitrogen_0.20_External_2_1" .

:M2282
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.S-0.2-aliquot2" .

:MN1575
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.3:out:0" ;
      isa:hasMaterial :M2579 ;
      isa:hasStudy :S2 .

:M2350
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.2-aliquot10" .

:MN2076
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.4:out:0" ;
      isa:hasMaterial :M2249 ;
      isa:hasStudy :S2 .

:DAN374
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.59" ;
      isa:hasInputNode :MN1935 ;
      isa:hasOutputNode :DN2005 ;
      isa:hasStudy :S2 .

:MN559
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.18" ;
      isa:hasInputNode :MN1870 ;
      isa:hasOutputNode :MN1546 ;
      isa:hasProtocolApplication
              :PA3424 ;
      isa:hasStudy :S2 .

:DN1641
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.29:out:0" ;
      isa:hasData :D3075 ;
      isa:hasStudy :S2 .

:MN1419
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.27:out:0" ;
      isa:hasMaterial :M2793 ;
      isa:hasStudy :S2 .

:M2428
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:hybridization:a_microarray.NZ_1hrs_Vehicle_Sample_2_Labelled_Hyb6" .

:M2979
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.E-0.1-aliquot3" .

:PA3814
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:M3884
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.G-0.07-aliquot6" .

:M2406
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.1-aliquot11" .

:MN63
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.2" ;
      isa:hasInputNode :MN1917 ;
      isa:hasOutputNode :MN1394 ;
      isa:hasProtocolApplication
              :PA2399 ;
      isa:hasStudy :S1 .

:DPN507
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.99" ;
      isa:hasInputNode :DN1566 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN761
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.53" ;
      isa:hasInputNode :MN1357 ;
      isa:hasOutputNode :MN1763 ;
      isa:hasProtocolApplication
              :PA3772 ;
      isa:hasStudy :S2 .

:MN2077
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.18:out:0" ;
      isa:hasMaterial :M2458 ;
      isa:hasStudy :S2 .

:D3577
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3954" ;
      isa:hasFactorValue :FV3580 , :FV3579 ;
      dcterms:title "SCAN:MEXP:3954" .

:MN1572
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.69:in:0" ;
      isa:hasMaterial :M3921 ;
      isa:hasStudy :S2 .

:DN1368
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.0:out:0" ;
      isa:hasData :D3218 ;
      isa:hasStudy :S1 .

:M2281
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.S-0.2-aliquot2" .

:DAN355
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.61" ;
      isa:hasInputNode :MN1622 ;
      isa:hasOutputNode :DN2115 ;
      isa:hasStudy :S2 .

:MN821
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.135" ;
      isa:hasInputNode :MN1431 ;
      isa:hasOutputNode :MN1696 ;
      isa:hasProtocolApplication
              :PA3848 ;
      isa:hasStudy :S2 .

:A1129
      a       isa:Assay .

:PA3973
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN974
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.54" ;
      isa:hasInputNode :MN1595 ;
      isa:hasOutputNode :MN1387 ;
      isa:hasStudy :S2 .

:D3843
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC41_Ethanol_0.10_Internal_2_1.txt" ;
      dcterms:title "JIC41_Ethanol_0.10_Internal_2_1.txt" .

:M3248
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC69_Nitrogen_0.10_External_3_1" .

isa:Factor
      rdfs:subClassOf isa:Property .

:M2351
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.N-0.2-aliquot10" .

:M2427
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:labelled_extract:a_microarray.NZ_1hrs_Vehicle_Sample_2_Labelled" .

:D3218
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_0hrs_Sample_1_Labelled_Hyb1_Scan1" ;
      isa:hasFactorValue :FV3220 , :FV3221 ;
      dcterms:title "NZ_0hrs_Sample_1_Labelled_Hyb1_Scan1" .

:M2401
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:hybridization:a_microarray.NZ_2hrs_Drug_Sample_1_Labelled_Hyb7" .

:MN760
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.54" ;
      isa:hasInputNode :MN1357 ;
      isa:hasOutputNode :MN1960 ;
      isa:hasProtocolApplication
              :PA3770 ;
      isa:hasStudy :S2 .

:PA3760
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DAN354
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.60" ;
      isa:hasInputNode :MN1354 ;
      isa:hasOutputNode :DN1420 ;
      isa:hasStudy :S2 .

:MN1573
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.3:out:0" ;
      isa:hasMaterial :M2252 ;
      isa:hasStudy :S2 .

:DN1425
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.3:out:0" ;
      isa:hasData :D2601 ;
      isa:hasStudy :S2 .

:MN975
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.53" ;
      isa:hasInputNode :MN1595 ;
      isa:hasOutputNode :MN1387 ;
      isa:hasStudy :S2 .

:MN822
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.54" ;
      isa:hasInputNode :MN1387 ;
      isa:hasOutputNode :MN1466 ;
      isa:hasStudy :S2 .

:M3249
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC70_Nitrogen_0.20_External_1_1" .

:PA2304
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:PA2286
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:PA3974
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:PA2417
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1109 .

:M3882
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.G-0.07-aliquot5" .

:PA2795
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M2400
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:labelled_extract:a_microarray.NZ_2hrs_Drug_Sample_1_Labelled" .

:PA2396
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1110 .

:PA3438
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1104 .

:DAN357
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.64" ;
      isa:hasInputNode :MN1969 ;
      isa:hasOutputNode :DN2170 ;
      isa:hasStudy :S2 .

:D3216
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_raw_data:a_microarray.NZ_0hrs_Sample_1_Labelled_Hyb1_Scan1" ;
      dcterms:title "NZ_0hrs_Sample_1_Labelled_Hyb1_Scan1" .

:D3575
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3924" ;
      dcterms:title "SCAN:MEXP:3924" .

:PA2289
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:MN972
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.52" ;
      isa:hasInputNode :MN1595 ;
      isa:hasOutputNode :MN1387 ;
      isa:hasStudy :S2 .

:D3092
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC10_Nitrogen_0.07_Internal_1_3.txt" ;
      dcterms:title "JIC10_Nitrogen_0.07_Internal_1_3.txt" .

:DAN379
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.73" ;
      isa:hasInputNode :MN1629 ;
      isa:hasOutputNode :DN2185 ;
      isa:hasStudy :S2 .

:DAN30
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.10" ;
      isa:hasInputNode :MN2114 ;
      isa:hasOutputNode :DN1518 ;
      isa:hasStudy :S2 .

:MN164
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.163" ;
      isa:hasInputNode :MN1411 ;
      isa:hasOutputNode :MN1813 ;
      isa:hasProtocolApplication
              :PA2703 ;
      isa:hasStudy :S2 .

:DAN428
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.34" ;
      isa:hasInputNode :MN1667 ;
      isa:hasOutputNode :DN1658 ;
      isa:hasStudy :S2 .

:MN60
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.1" ;
      isa:hasInputNode :MN2209 ;
      isa:hasOutputNode :MN1689 ;
      isa:hasProtocolApplication
              :PA2390 ;
      isa:hasStudy :S1 .

:M2403
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:labelled_extract:a_microarray.NZ_4hrs_Drug_Sample_1_Labelled" .

:PA2798
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:FV3314
      a       isa:FactorValue .

:M2425
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:hybridization:a_microarray.NZ_2hrs_Vehicle_Sample_2_Labelled_Hyb10" .

:M2353
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:N-0.07-aliquot5" .

:DPN725
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.29" ;
      isa:hasInputNode :DN1561 ;
      isa:hasOutputNode :DN2090 ;
      isa:hasStudy :S2 .

:PA3762
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DPN378
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.48" ;
      isa:hasInputNode :DN2099 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN973
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.51" ;
      isa:hasInputNode :MN1996 ;
      isa:hasOutputNode :MN1773 ;
      isa:hasStudy :S2 .

:DN1940
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.9:out:0" ;
      isa:hasData :D3212 ;
      isa:hasStudy :S2 .

:M3880
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.C-0.1-aliquot7" .

:M2424
      a       isa:Material ;
      isa:hasAccessionID "BII-S-2:labelled_extract:a_microarray.NZ_2hrs_Vehicle_Sample_2_Labelled" .

:D3090
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC102_GlucoseO2_0.07_External_3_1.txt" ;
      dcterms:title "JIC102_GlucoseO2_0.07_External_3_1.txt" .

:M2354
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.N-0.07-aliquot5" .

:DPN687
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.18" ;
      isa:hasInputNode :DN1635 ;
      isa:hasOutputNode :DN1907 ;
      isa:hasStudy :S2 .

:FV3313
      a       isa:FactorValue .

:MN1911
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.7:out:0" ;
      isa:hasMaterial :M2669 ;
      isa:hasStudy :S2 .

:MN809
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.131" ;
      isa:hasInputNode :MN1335 ;
      isa:hasOutputNode :MN1590 ;
      isa:hasProtocolApplication
              :PA3832 ;
      isa:hasStudy :S2 .

:M3669
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:source:culture4" .

:OE3161
      a       isa:OntologyEntry .

:M3440
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.07-aliquot2" .

:PA2843
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:OE3223
      a       isa:OntologyEntry .

:MN608
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.42" ;
      isa:hasInputNode :MN1818 ;
      isa:hasOutputNode :MN1983 ;
      isa:hasProtocolApplication
              :PA3497 ;
      isa:hasStudy :S2 .

:DPN733
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.33" ;
      isa:hasInputNode :DN1512 ;
      isa:hasOutputNode :DN2148 ;
      isa:hasStudy :S2 .

:D3348
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_2hrs_Drug_Sample_2_Labelled_Hyb8_Scan8" ;
      isa:hasFactorValue :FV3350 , :FV3352 , :FV3351 ;
      dcterms:title "NZ_2hrs_Drug_Sample_2_Labelled_Hyb8_Scan8" .

:A1144
      a       isa:Assay .

:DPN491
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.85" ;
      isa:hasInputNode :DN1580 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DN1435
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.15:out:0" ;
      isa:hasData :D3640 ;
      isa:hasStudy :S2 .

:MN2092
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.120:out:0" ;
      isa:hasMaterial :M3486 ;
      isa:hasStudy :S2 .

:PA3435
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1104 .

:MN752
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.111" ;
      isa:hasInputNode :MN1441 ;
      isa:hasOutputNode :MN1946 ;
      isa:hasProtocolApplication
              :PA3762 ;
      isa:hasStudy :S2 .

:P_1105
      a       isa:Protocol ;
      rdfs:label "biotin labeling"^^xsd:string ;
      isa:hasAccessionID "BII-S-1\\biotin labeling" ;
      dcterms:description "This was done using Enzo BioArrayTM HighYieldTM RNA transcript labelling kit (T7) with 5 ul cDNA. The resultant cRNA was again purified using the GeneChip �_� Sample Clean Up Module. The column was eluted in the first instance using 10 �_�l RNase-free water, and for a second time using 11 ul RNase-free water. cRNA was quantified using the Nanodrop spectrophotometer. A total of 15 ug of cRNA (required for hybridisation) was fragmented. Fragmentation was carried out by using 2 ul of fragmentation buffer for every 8 ul cRNA." .

:DAN424
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.36" ;
      isa:hasInputNode :MN1891 ;
      isa:hasOutputNode :DN1865 ;
      isa:hasStudy :S2 .

:DPN511
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.9" ;
      isa:hasInputNode :DN1412 ;
      isa:hasOutputNode :DN1451 ;
      isa:hasStudy :S1 .

:MN692
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.11" ;
      isa:hasInputNode :MN1482 ;
      isa:hasOutputNode :MN1444 ;
      isa:hasStudy :S2 .

:MN1491
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.106:out:0" ;
      isa:hasMaterial :M3500 ;
      isa:hasStudy :S2 .

:MN774
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.102" ;
      isa:hasInputNode :MN1445 ;
      isa:hasOutputNode :MN1398 ;
      isa:hasProtocolApplication
              :PA3784 ;
      isa:hasStudy :S2 .

:MN1794
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.101:out:0" ;
      isa:hasMaterial :M2627 ;
      isa:hasStudy :S2 .

:MN185
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.60" ;
      isa:hasInputNode :MN1715 ;
      isa:hasOutputNode :MN1636 ;
      isa:hasProtocolApplication
              :PA2743 ;
      isa:hasStudy :S2 .

:DN1579
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.18:out:0" ;
      isa:hasData :D3011 ;
      isa:hasStudy :S2 .

:MN1912
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.8:out:0" ;
      isa:hasMaterial :M2287 ;
      isa:hasStudy :S2 .

:M2421
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.1-aliquot11" .

:M3441
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.07-aliquot1" .

:MN609
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.40" ;
      isa:hasInputNode :MN1491 ;
      isa:hasOutputNode :MN1982 ;
      isa:hasProtocolApplication
              :PA3499 ;
      isa:hasStudy :S2 .

:MN2091
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.83:out:0" ;
      isa:hasMaterial :M2820 ;
      isa:hasStudy :S2 .

:A1143
      a       isa:Assay .

:P_1104
      a       isa:Protocol ;
      rdfs:label "ITRAQ labeling"^^xsd:string ;
      isa:hasAccessionID "BII-S-1\\ITRAQ labeling" .

:MN753
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.37" ;
      isa:hasInputNode :MN2212 ;
      isa:hasOutputNode :MN2124 ;
      isa:hasStudy :S2 .

:PA3765
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DN1507
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.87:out:0" ;
      isa:hasData :D2994 ;
      isa:hasStudy :S2 .

:DPN510
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.97" ;
      isa:hasInputNode :DN2197 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN775
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.42" ;
      isa:hasInputNode :MN1340 ;
      isa:hasOutputNode :MN2138 ;
      isa:hasStudy :S2 .

:MN184
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.61" ;
      isa:hasInputNode :MN1686 ;
      isa:hasOutputNode :MN1727 ;
      isa:hasProtocolApplication
              :PA2740 ;
      isa:hasStudy :S2 .

:MN1795
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.10:out:0" ;
      isa:hasMaterial :M2858 ;
      isa:hasStudy :S2 .

:MN1492
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.26:out:0" ;
      isa:hasMaterial :M2730 ;
      isa:hasStudy :S2 .

:M2422
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_proteome.P-0.1" .

:PA3808
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DPN735
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.34" ;
      isa:hasInputNode :DN1372 ;
      isa:hasOutputNode :DN2204 ;
      isa:hasStudy :S2 .

:MN606
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.44" ;
      isa:hasInputNode :MN1867 ;
      isa:hasOutputNode :MN1868 ;
      isa:hasProtocolApplication
              :PA3493 ;
      isa:hasStudy :S2 .

:M2625
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3907" .

:M2848
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3923" .

:PA2841
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:M3442
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.E-0.07-aliquot3" .

:P_1107
      a       isa:Protocol ;
      rdfs:label "metabolite extraction"^^xsd:string ;
      isa:hasAccessionID "BII-S-1\\metabolite extraction" .

:DN1577
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.72:out:0" ;
      isa:hasData :D3158 ;
      isa:hasStudy :S2 .

:A1142
      a       isa:Assay .

:PA3764
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN776
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.101" ;
      isa:hasInputNode :MN1445 ;
      isa:hasOutputNode :MN1794 ;
      isa:hasProtocolApplication
              :PA3786 ;
      isa:hasStudy :S2 .

:DPN513
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.98" ;
      isa:hasInputNode :DN1783 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN1792
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.91:out:0" ;
      isa:hasMaterial :M3914 ;
      isa:hasStudy :S2 .

:MN187
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.68" ;
      isa:hasInputNode :MN1597 ;
      isa:hasOutputNode :MN1423 ;
      isa:hasProtocolApplication
              :PA2749 ;
      isa:hasStudy :S2 .

:DAN426
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.33" ;
      isa:hasInputNode :MN1859 ;
      isa:hasOutputNode :DN1503 ;
      isa:hasStudy :S2 .

:MN750
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.38" ;
      isa:hasInputNode :MN2143 ;
      isa:hasOutputNode :MN1856 ;
      isa:hasStudy :S2 .

:OE3721
      a       isa:OntologyEntry .

:M3509
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC89_Sulphate_0.20_External_2_1" .

:PA2626
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN1914
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.8:out:0" ;
      isa:hasMaterial :M2672 ;
      isa:hasStudy :S2 .

:PA3809
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN607
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.41" ;
      isa:hasInputNode :MN1908 ;
      isa:hasOutputNode :MN1769 ;
      isa:hasProtocolApplication
              :PA3495 ;
      isa:hasStudy :S2 .

:P_1106
      a       isa:Protocol ;
      rdfs:label "biotin labeling"^^xsd:string ;
      isa:hasAccessionID "BII-S-2\\biotin labeling" ;
      dcterms:description "This was done using Enzo BioArrayTM HighYieldTM RNA transcript labelling kit (T7) with 5 ul cDNA. The resultant cRNA was again purified using the GeneChip �_� Sample Clean Up Module. The column was eluted in the first instance using 10 �_�l RNase-free water, and for a second time using 11 �_�l RNase-free water. cRNA was quantified using the Nanodrop spectrophotometer. A total of 15 ug of cRNA (required for hybridisation) was fragmented. Fragmentation was carried out by using 2 ul of fragmentation buffer for every 8 ul cRNA." .

:DAN381
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.74" ;
      isa:hasInputNode :MN1548 ;
      isa:hasOutputNode :DN1916 ;
      isa:hasStudy :S2 .

:MN1411
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.163:in:0" ;
      isa:hasMaterial :M2691 ;
      isa:hasStudy :S2 .

:MN751
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.46" ;
      isa:hasInputNode :MN1336 ;
      isa:hasOutputNode :MN2220 ;
      isa:hasProtocolApplication
              :PA3760 ;
      isa:hasStudy :S2 .

:A1141
      a       isa:Assay .

:MN2000
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.9:out:0" ;
      isa:hasMaterial :M2573 ;
      isa:hasStudy :S2 .

:DAN570
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.3" ;
      isa:hasInputNode :MN1388 ;
      isa:hasOutputNode :DN1425 ;
      isa:hasStudy :S2 .

:PA3432
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1104 .

:MN1793
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.149:out:0" ;
      isa:hasMaterial :M2779 ;
      isa:hasStudy :S2 .

:DN1658
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.34:out:0" ;
      isa:hasData :D3082 ;
      isa:hasStudy :S2 .

:MN777
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.39" ;
      isa:hasInputNode :MN1567 ;
      isa:hasOutputNode :MN1343 ;
      isa:hasProtocolApplication
              :PA3787 ;
      isa:hasStudy :S2 .

:MN186
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.69" ;
      isa:hasInputNode :MN1837 ;
      isa:hasOutputNode :MN2096 ;
      isa:hasProtocolApplication
              :PA2746 ;
      isa:hasStudy :S2 .

:MN1415
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.12:out:0" ;
      isa:hasMaterial :M2439 ;
      isa:hasStudy :S2 .

:P_1109
      a       isa:Protocol ;
      rdfs:label "protein extraction"^^xsd:string ;
      isa:hasAccessionID "BII-S-1\\protein extraction" .

:OE3012
      a       isa:OntologyEntry .

:M2846
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3926" .

:MN181
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.66" ;
      isa:hasInputNode :MN1857 ;
      isa:hasOutputNode :MN1671 ;
      isa:hasProtocolApplication
              :PA2731 ;
      isa:hasStudy :S2 .

:MN1915
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.3:out:0" ;
      isa:hasMaterial :M3501 ;
      isa:hasStudy :S2 .

:M3251
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC66_Nitrogen_0.07_External_3_1" .

:MN778
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.45" ;
      isa:hasInputNode :MN1620 ;
      isa:hasOutputNode :MN1800 ;
      isa:hasStudy :S2 .

:PA2512
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:MN1052
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.6" ;
      isa:hasInputNode :MN2010 ;
      isa:hasOutputNode :MN1852 ;
      isa:hasStudy :S2 .

:DPN515
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.95" ;
      isa:hasInputNode :DN2163 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:A1148
      a       isa:Assay .

:DAN420
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.38" ;
      isa:hasInputNode :MN1856 ;
      isa:hasOutputNode :DN1986 ;
      isa:hasStudy :S2 .

isa:Material
      rdfs:subClassOf isa:Accessible .

:DAN573
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.1" ;
      isa:hasInputNode :MN1665 ;
      isa:hasOutputNode :DN1691 ;
      isa:hasStudy :S2 .

:MN2096
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.69:out:0" ;
      isa:hasMaterial :M2748 ;
      isa:hasStudy :S2 .

:PA3431
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1106 .

:MN1790
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.0.2.6:out:0" ;
      isa:hasMaterial :M2416 ;
      isa:hasStudy :S2 .

:MN603
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.45" ;
      isa:hasInputNode :MN1430 ;
      isa:hasOutputNode :MN1745 ;
      isa:hasProtocolApplication
              :PA3487 ;
      isa:hasStudy :S2 .

:MN756
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.36" ;
      isa:hasInputNode :MN2029 ;
      isa:hasOutputNode :MN1891 ;
      isa:hasStudy :S2 .

:MN1495
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.92:out:0" ;
      isa:hasMaterial :M3913 ;
      isa:hasStudy :S2 .

:OE3227
      a       isa:OntologyEntry .

:PA3645
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN543
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.0" ;
      isa:hasInputNode :MN1717 ;
      isa:hasOutputNode :MN1470 ;
      isa:hasProtocolApplication
              :PA3392 ;
      isa:hasStudy :S2 .

:MN1414
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.36:out:0" ;
      isa:hasMaterial :M2771 ;
      isa:hasStudy :S2 .

:PA2847
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:M2299
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.S-0.1-aliquot4" .

:MN605
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.43" ;
      isa:hasInputNode :MN2166 ;
      isa:hasOutputNode :MN1909 ;
      isa:hasProtocolApplication
              :PA3491 ;
      isa:hasStudy :S2 .

:DPN894
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.110" ;
      isa:hasInputNode :DN2165 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN180
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.26" ;
      isa:hasInputNode :MN2106 ;
      isa:hasOutputNode :MN1492 ;
      isa:hasProtocolApplication
              :PA2729 ;
      isa:hasStudy :S2 .

:PA3769
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:ISA_3980
      a       foaf:Person , isa:Contact ;
      foaf:family_name "Oliver"^^xsd:string ;
      foaf:givenname "Stephen"^^xsd:string .

:MN804
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.133" ;
      isa:hasInputNode :MN1335 ;
      isa:hasOutputNode :MN1707 ;
      isa:hasProtocolApplication
              :PA3825 ;
      isa:hasStudy :S2 .

:M3250
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC65_Nitrogen_0.07_External_2_1" .

:PA2624
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN779
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.44" ;
      isa:hasInputNode :MN1660 ;
      isa:hasOutputNode :MN2110 ;
      isa:hasStudy :S2 .

:DAN361
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.62" ;
      isa:hasInputNode :MN1711 ;
      isa:hasOutputNode :DN1901 ;
      isa:hasStudy :S2 .

:PA3430
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1106 .

:M2570
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.S-0.07-aliquot2" .

:A1147
      a       isa:Assay .

:MN1051
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.9" ;
      isa:hasInputNode :MN1382 ;
      isa:hasOutputNode :MN2202 ;
      isa:hasStudy :S2 .

:MN2002
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.106:out:0" ;
      isa:hasMaterial :M2918 ;
      isa:hasStudy :S2 .

:MN757
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.48" ;
      isa:hasInputNode :MN1336 ;
      isa:hasOutputNode :MN1815 ;
      isa:hasProtocolApplication
              :PA3767 ;
      isa:hasStudy :S2 .

:MN1496
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.100:out:0" ;
      isa:hasMaterial :M2982 ;
      isa:hasStudy :S2 .

:DAN383
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.75" ;
      isa:hasInputNode :MN1993 ;
      isa:hasOutputNode :DN1356 ;
      isa:hasStudy :S2 .

:DAN572
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.2" ;
      isa:hasInputNode :MN2179 ;
      isa:hasOutputNode :DN2019 ;
      isa:hasStudy :S2 .

:MN604
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.46" ;
      isa:hasInputNode :MN2155 ;
      isa:hasOutputNode :MN1903 ;
      isa:hasProtocolApplication
              :PA3489 ;
      isa:hasStudy :S2 .

:MN542
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.1" ;
      isa:hasInputNode :MN1712 ;
      isa:hasOutputNode :MN1733 ;
      isa:hasProtocolApplication
              :PA3390 ;
      isa:hasStudy :S2 .

:MN1413
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.160:out:0" ;
      isa:hasMaterial :M2696 ;
      isa:hasStudy :S2 .

:P_1108
      a       isa:Protocol ;
      rdfs:label "growth"^^xsd:string ;
      isa:hasAccessionID "BII-S-2\\growth" ;
      dcterms:description "The culture was grown in YMB minimum media + 2% glucose + supplement to early exponential growth (OD ~0.32)" .

:M2844
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3924" .

:DPN731
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.30" ;
      isa:hasInputNode :DN1936 ;
      isa:hasOutputNode :DN1709 ;
      isa:hasStudy :S2 .

:MN1417
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.94:out:0" ;
      isa:hasMaterial :M2871 ;
      isa:hasStudy :S2 .

:OE3010
      a       isa:OntologyEntry .

:DPN681
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.16" ;
      isa:hasInputNode :DN2032 ;
      isa:hasOutputNode :DN1454 ;
      isa:hasStudy :S2 .

:ISA_3981
      a       foaf:Person , isa:Contact ;
      foaf:family_name "Juan"^^xsd:string ;
      foaf:givenname "Castrillo"^^xsd:string .

:MN1917
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.2:out:0" ;
      isa:hasMaterial :M2400 ;
      isa:hasStudy :S1 .

:MN807
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.57" ;
      isa:hasInputNode :MN2215 ;
      isa:hasOutputNode :MN2173 ;
      isa:hasStudy :S2 .

:M2571
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_transcriptome.S-0.07-aliquot2" .

:DPN517
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.96" ;
      isa:hasInputNode :DN2054 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:M3131
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC4_Carbon_0.10_Internal_1_1" .

:MN183
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.62" ;
      isa:hasInputNode :MN1377 ;
      isa:hasOutputNode :MN2112 ;
      isa:hasProtocolApplication
              :PA2737 ;
      isa:hasStudy :S2 .

:A1146
      a       isa:Assay .

:MN2003
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.36:out:0" ;
      isa:hasMaterial :M2567 ;
      isa:hasStudy :S2 .

:DAN422
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.35" ;
      isa:hasInputNode :MN1437 ;
      isa:hasOutputNode :DN1973 ;
      isa:hasStudy :S2 .

:MN541
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.2" ;
      isa:hasInputNode :MN1504 ;
      isa:hasOutputNode :MN1616 ;
      isa:hasProtocolApplication
              :PA3388 ;
      isa:hasStudy :S2 .

:ISA_3982
      a       foaf:Person , isa:Contact ;
      foaf:family_name "Oliver"^^xsd:string ;
      foaf:givenname "Stephen"^^xsd:string .

:M3253
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC68_Nitrogen_0.10_External_2_1" .

:MN1050
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.21" ;
      isa:hasInputNode :MN2074 ;
      isa:hasOutputNode :MN1860 ;
      isa:hasStudy :S2 .

:PA2845
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1103 .

:MN754
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.47" ;
      isa:hasInputNode :MN1336 ;
      isa:hasOutputNode :MN1823 ;
      isa:hasProtocolApplication
              :PA3764 ;
      isa:hasStudy :S2 .

:OE3225
      a       isa:OntologyEntry .

:MN1416
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.16:out:0" ;
      isa:hasMaterial :M3264 ;
      isa:hasStudy :S2 .

:MN806
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.130" ;
      isa:hasInputNode :MN1335 ;
      isa:hasOutputNode :MN1923 ;
      isa:hasProtocolApplication
              :PA3828 ;
      isa:hasStudy :S2 .

:M3252
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC67_Nitrogen_0.10_External_1_1" .

:DAN574
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.0" ;
      isa:hasInputNode :MN2141 ;
      isa:hasOutputNode :DN1756 ;
      isa:hasStudy :S2 .

:MN1494
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.43:out:0" ;
      isa:hasMaterial :M2689 ;
      isa:hasStudy :S2 .

:MN2004
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.6:out:0" ;
      isa:hasMaterial :M2939 ;
      isa:hasStudy :S1 .

:A1145
      a       isa:Assay .

:MN182
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.65" ;
      isa:hasInputNode :MN1674 ;
      isa:hasOutputNode :MN1967 ;
      isa:hasProtocolApplication
              :PA2734 ;
      isa:hasStudy :S2 .

:OE3726
      a       isa:OntologyEntry .

:PA3767
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN2093
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.61:out:0" ;
      isa:hasMaterial :M2314 ;
      isa:hasStudy :S2 .

:DAN385
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.76" ;
      isa:hasInputNode :MN1780 ;
      isa:hasOutputNode :DN1401 ;
      isa:hasStudy :S2 .

:MN602
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.47" ;
      isa:hasInputNode :MN2092 ;
      isa:hasOutputNode :MN2011 ;
      isa:hasProtocolApplication
              :PA3485 ;
      isa:hasStudy :S2 .

:MN755
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.110" ;
      isa:hasInputNode :MN1441 ;
      isa:hasOutputNode :MN1528 ;
      isa:hasProtocolApplication
              :PA3765 ;
      isa:hasStudy :S2 .

:MN1643
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.53:out:0" ;
      isa:hasMaterial :M3242 ;
      isa:hasStudy :S2 .

:MN1056
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.25" ;
      isa:hasInputNode :MN2103 ;
      isa:hasOutputNode :MN1830 ;
      isa:hasStudy :S2 .

:MN2110
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.44:out:0" ;
      isa:hasMaterial :M3250 ;
      isa:hasStudy :S2 .

:DN1571
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.0:out:0" ;
      isa:hasData :D3216 ;
      isa:hasStudy :S1 .

:DN1714
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.6:out:0" ;
      isa:hasData :D2645 ;
      isa:hasStudy :S2 .

:DPN499
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.2" ;
      isa:hasInputNode :DN1390 ;
      isa:hasOutputNode :DN1666 ;
      isa:hasStudy :S1 .

:A1257
      a       isa:Assay .

:DN1791
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.38:out:0" ;
      isa:hasData :D3597 ;
      isa:hasStudy :S2 .

:M2842
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3925" .

:M3448
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.2-aliquot2" .

:DPN406
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.9" ;
      isa:hasInputNode :DN1940 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN290
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.2" ;
      isa:hasInputNode :MN1720 ;
      isa:hasOutputNode :MN1956 ;
      isa:hasProtocolApplication
              :PA2942 ;
      isa:hasStudy :S2 .

:MN1849
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.77:out:0" ;
      isa:hasMaterial :M3038 ;
      isa:hasStudy :S2 .

:M2573
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:hybridization:a_transcriptome.HYB:MEXP:3915" .

:M3504
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC36_Sulphate_0.20_Internal_1_3" .

:M2780
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.G-0.07-aliquot4" .

:DN1928
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.36:out:0" ;
      isa:hasData :D3605 ;
      isa:hasStudy :S2 .

:DN1570
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.5:out:0" ;
      isa:hasData :D3316 ;
      isa:hasStudy :S1 .

:OE3169
      a       isa:OntologyEntry .

:MN1055
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.4" ;
      isa:hasInputNode :MN1375 ;
      isa:hasOutputNode :MN2080 ;
      isa:hasStudy :S2 .

:DN1916
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.74:out:0" ;
      isa:hasData :D3168 ;
      isa:hasStudy :S2 .

:MN600
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.28" ;
      isa:hasInputNode :MN1672 ;
      isa:hasOutputNode :MN1489 ;
      isa:hasProtocolApplication
              :PA3481 ;
      isa:hasStudy :S2 .

:A1256
      a       isa:Assay .

:MN2111
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.47:out:0" ;
      isa:hasMaterial :M3253 ;
      isa:hasStudy :S2 .

:DAN644
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.17" ;
      isa:hasInputNode :MN1747 ;
      isa:hasOutputNode :DN2015 ;
      isa:hasStudy :S2 .

:M3503
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC82_Sulphate_0.07_External_1_1" .

:MN1848
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.5:out:0" ;
      isa:hasMaterial :M2264 ;
      isa:hasStudy :S2 .

:M3021
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC51_GlucoseO2_0.10_Internal_3_1" .

:PA2515
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M3710
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.1-aliquot7" .

:OE3375
      a       isa:OntologyEntry .

:OE3229
      a       isa:OntologyEntry .

:MN698
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.32" ;
      isa:hasInputNode :MN1567 ;
      isa:hasOutputNode :MN2109 ;
      isa:hasProtocolApplication
              :PA3668 ;
      isa:hasStudy :S2 .

:DN1865
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.36:out:0" ;
      isa:hasData :D3109 ;
      isa:hasStudy :S2 .

:DN1913
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.20:out:0" ;
      isa:hasData :D3613 ;
      isa:hasStudy :S2 .

:MN758
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.35" ;
      isa:hasInputNode :MN1777 ;
      isa:hasOutputNode :MN1437 ;
      isa:hasStudy :S2 .

:MN2112
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.62:out:0" ;
      isa:hasMaterial :M2739 ;
      isa:hasStudy :S2 .

:MN1054
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.24" ;
      isa:hasInputNode :MN1882 ;
      isa:hasOutputNode :MN1534 ;
      isa:hasStudy :S2 .

:MN292
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.6" ;
      isa:hasInputNode :MN1790 ;
      isa:hasOutputNode :MN1487 ;
      isa:hasProtocolApplication
              :PA2944 ;
      isa:hasStudy :S2 .

:A1255
      a       isa:Assay .

:DPN497
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.3" ;
      isa:hasInputNode :DN1905 ;
      isa:hasOutputNode :DN2014 ;
      isa:hasStudy :S1 .

:M2575
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:S-0.07-aliquot5" .

:OE2652
      a       isa:OntologyEntry .

:M2782
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:G-0.07-aliquot5" .

:DPN408
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.0" ;
      isa:hasInputNode :DN1809 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DN2140
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.51:out:0" ;
      isa:hasData :D3198 ;
      isa:hasStudy :S2 .

:M2840
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.G-0.1-aliquot1" .

:MN1646
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.42:out:0" ;
      isa:hasMaterial :M2354 ;
      isa:hasStudy :S2 .

:M3502
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC83_Sulphate_0.07_External_2_1" .

:DAN888
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.4" ;
      isa:hasInputNode :MN2167 ;
      isa:hasOutputNode :DN2225 ;
      isa:hasStudy :S1 .

:MN759
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.49" ;
      isa:hasInputNode :MN1336 ;
      isa:hasOutputNode :MN1383 ;
      isa:hasProtocolApplication
              :PA3769 ;
      isa:hasStudy :S2 .

:D3343
      a       isa:Data ;
      isa:hasAccessionID "BII-S-2:microarray_normalized_data:a_microarray.NZ_4hrs_Vehicle_Sample_2_Labelled_Hyb14_Scan14" ;
      isa:hasFactorValue :FV3346 , :FV3347 , :FV3345 ;
      dcterms:title "NZ_4hrs_Vehicle_Sample_2_Labelled_Hyb14_Scan14" .

:A1254
      a       isa:Assay .

:MN2113
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.11:out:0" ;
      isa:hasMaterial :M2428 ;
      isa:hasStudy :S1 .

:MN1053
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.7" ;
      isa:hasInputNode :MN2101 ;
      isa:hasOutputNode :MN1613 ;
      isa:hasStudy :S2 .

:DN1864
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.79:out:0" ;
      isa:hasData :D3029 ;
      isa:hasStudy :S2 .

:DPN498
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.92" ;
      isa:hasInputNode :DN1490 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DAN642
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.18" ;
      isa:hasInputNode :MN1457 ;
      isa:hasOutputNode :DN1635 ;
      isa:hasStudy :S2 .

:M2576
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.S-0.07-aliquot5" .

:DPN407
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.59" ;
      isa:hasInputNode :DN2005 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN291
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.3" ;
      isa:hasInputNode :MN1720 , :MN1564 , :MN1397 ;
      isa:hasOutputNode :MN1806 ;
      isa:hasProtocolApplication
              :PA2943 ;
      isa:hasStudy :S2 .

:OE3373
      a       isa:OntologyEntry .

:M3501
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC84_Sulphate_0.07_External_3_1" .

:DAN887
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.5" ;
      isa:hasInputNode :MN1701 ;
      isa:hasOutputNode :DN1570 ;
      isa:hasStudy :S1 .

:MN1647
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.12:out:0" ;
      isa:hasMaterial :M2440 ;
      isa:hasStudy :S2 .

:FV3702
      a       isa:FactorValue .

:MN1798
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.64:out:0" ;
      isa:hasMaterial :M3857 ;
      isa:hasStudy :S2 .

:PA3875
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:DPN402
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.57" ;
      isa:hasInputNode :DN1744 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN294
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.8" ;
      isa:hasInputNode :MN1836 ;
      isa:hasOutputNode :MN2022 ;
      isa:hasProtocolApplication
              :PA2948 ;
      isa:hasStudy :S2 .

:A1253
      a       isa:Assay .

:DPN495
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.7.8.4" ;
      isa:hasInputNode :DN2225 ;
      isa:hasOutputNode :DN1991 ;
      isa:hasStudy :S1 .

:MN696
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.30" ;
      isa:hasInputNode :MN1360 ;
      isa:hasOutputNode :MN1377 ;
      isa:hasProtocolApplication
              :PA3663 ;
      isa:hasStudy :S2 .

:A1140
      a       isa:Assay .

:M3444
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.1-aliquot4" .

:M2627
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:S-0.07-aliquot6" .

:PA3919
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1109 .

:OE2650
      a       isa:OntologyEntry .

:M3508
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC82_Sulphate_0.07_External_1_2" .

:MN1845
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.58:out:0" ;
      isa:hasMaterial :M3833 ;
      isa:hasStudy :S2 .

:DN1796
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.10:out:0" ;
      isa:hasData :D2884 ;
      isa:hasStudy :S1 .

:MN1799
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.2.4.20:out:0" ;
      isa:hasMaterial :M2475 ;
      isa:hasStudy :S2 .

:MN1843
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.13:out:0" ;
      isa:hasMaterial :M3434 ;
      isa:hasStudy :S2 .

:DPN401
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.7" ;
      isa:hasInputNode :DN1312 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:DAN640
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.11" ;
      isa:hasInputNode :MN1341 ;
      isa:hasOutputNode :DN1900 ;
      isa:hasStudy :S2 .

:DN1503
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.33:out:0" ;
      isa:hasData :D3087 ;
      isa:hasStudy :S2 .

:PA3874
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:A1252
      a       isa:Assay .

:MN1640
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.9:out:0" ;
      isa:hasMaterial :M2815 ;
      isa:hasStudy :S2 .

:MN1059
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.2" ;
      isa:hasInputNode :MN1782 ;
      isa:hasOutputNode :MN1332 ;
      isa:hasStudy :S2 .

:MN1000
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.40" ;
      isa:hasInputNode :MN2157 ;
      isa:hasOutputNode :MN2007 ;
      isa:hasStudy :S2 .

:A1192
      a       isa:Assay .

:DPN496
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.91" ;
      isa:hasInputNode :DN1472 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:A1191
      a       isa:Assay .

:OE3166
      a       isa:OntologyEntry .

:OE3371
      a       isa:OntologyEntry .

:MN1844
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.15:out:0" ;
      isa:hasMaterial :M3263 ;
      isa:hasStudy :S2 .

:M2783
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.G-0.07-aliquot5" .

:M2578
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:S-0.07-aliquot7" .

:M3507
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC82_Sulphate_0.07_External_1_3" .

:M3714
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.P-0.07-aliquot6" .

:DPN404
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.8" ;
      isa:hasInputNode :DN1669 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN296
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.9" ;
      isa:hasInputNode :MN1790 , :MN1836 , :MN1581 ;
      isa:hasOutputNode :MN1640 ;
      isa:hasProtocolApplication
              :PA2950 ;
      isa:hasStudy :S2 .

:MN694
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.10" ;
      isa:hasInputNode :MN2183 ;
      isa:hasOutputNode :MN2114 ;
      isa:hasStudy :S2 .

:DN1797
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.26:out:0" ;
      isa:hasData :D3694 ;
      isa:hasStudy :S2 .

:MN1058
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.22" ;
      isa:hasInputNode :MN1350 ;
      isa:hasOutputNode :MN1353 ;
      isa:hasStudy :S2 .

:DN1716
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.6.7.26:out:0" ;
      isa:hasData :D3521 ;
      isa:hasStudy :S2 .

:OE2987
      a       isa:OntologyEntry .

:A1251
      a       isa:Assay .

:P_1103
      a       isa:Protocol ;
      rdfs:label "EukGE-WS4"^^xsd:string ;
      isa:hasAccessionID "BII-S-1\\EukGE-WS4" ;
      dcterms:description "For each target, a hybridisation cocktail was made using the standard array recipe as described in the GeneChip �_� Expression Analysis technical manual. GeneChip �_� control oligonucleotide and 20x eukaryotic hybridisation controls were used. Hybridisation buffer was made as detailed in the GeneChip �_� manual and the BSA and herring sperm DNA was purchased from Invitrogen. The cocktail was heated to 99 C for 5 min, transferred to 45 C for 5 min and then spun for 5 min to remove any insoluble material. Affymetrix Yeast Yg_s98 S. cerevisiae arrays were pre-hybridised with 200 ul 1x hybridisation buffer and incubated at 45 C for 10 min. 200 ul of the hybridisation cocktail was loaded onto the arrays. The probe array was incubated in a rotisserie at 45 C, rotating at 60 rpm. Following hybridisation, for 16 hr, chips were loaded onto a Fluidics station for washing and staining using the EukGe WS2v4 programme controlled using Microarray Suite 5 software." .

:M3446
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:P-0.1-aliquot3" .

:M2579
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_metabolome.S-0.07-aliquot7" .

:PA2518
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1107 .

:M3506
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:ms_spec:a_metabolome.JIC85_Sulphate_0.10_External_1_1" .

:PA3917
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1109 .

:FV3673
      a       isa:FactorValue .

:PA3872
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:MN295
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.7" ;
      isa:hasInputNode :MN1581 ;
      isa:hasOutputNode :MN1765 ;
      isa:hasProtocolApplication
              :PA2949 ;
      isa:hasStudy :S2 .

:MN1841
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.69:out:0" ;
      isa:hasMaterial :M3188 ;
      isa:hasStudy :S2 .

:MN693
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.29" ;
      isa:hasInputNode :MN1360 ;
      isa:hasOutputNode :MN1686 ;
      isa:hasProtocolApplication
              :PA3657 ;
      isa:hasStudy :S2 .

:A1250
      a       isa:Assay .

:DN1501
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.7.8.1:out:0" ;
      isa:hasData :D2707 ;
      isa:hasStudy :S2 .

:MN1642
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.4.6.10:out:0" ;
      isa:hasMaterial :M2431 ;
      isa:hasStudy :S1 .

:P_1102
      a       isa:Protocol ;
      rdfs:label "mRNA  extraction"^^xsd:string ;
      isa:hasAccessionID "BII-S-2\\mRNA  extraction" ;
      dcterms:description """1. Biomass samples (45ml) were taken via the sample port of the Applikon fermenters. The cells were pelleted by centrifugation for 5min at 5000 rpm. The supernatant was removed and the RNA pellet resuspended in the residual medium to form a slurry. This was added in a dropwise manner directly into a 5ml Teflon flask (B. Braun Biotech, Germany) containing liquid nitrogen and a 7 mm-diameter tungsten carbide ball. After allowing evaporation of the liquid nitrogen the flask was reassembled and the cells disrupted by agitation at 1500 rpm for 2 min in a Microdismembranator U (B. Braun Biotech, Germany) 

2. The frozen powder was then dissolved in 1 ml of TriZol reagent (Sigma-Aldrich, UK), vortexed for 1 min, and then kept at room temperature for a further 5 min. 

3. Chloroform extraction was performed by addition of 0.2 ml chloroform, shaking vigorouslyor 15 s, then 5 min incubation at room temperature. 

4. Following centrifugation at 12,000 rpm for 5 min, the RNA (contained in the aqueous phase) was precipitated with 0.5 vol of 2-propanol at room temperature for 15 min. 
5. After further centrifugation (12,000 rpm for 10 min at 4 C) the RNA pellet was washed twice with 70 % (v/v) ethanol, briefly air-dried, and redissolved in 0.5 ml diethyl pyrocarbonate (DEPC)-treated water. 

6. The single-stranded RNA was precipitated once more by addition of 0.5 ml of LiCl bffer (4 M LiCl, 20 mM Tris-HCl, pH 7.5, 10 mM EDTA), thus removing tRNA and DNA from the sample. 

7. After precipitation (20 C for 1h) and centrifugation (12,000 rpm, 30 min, 4 C), the RNA was washed twice in 70 % (v/v) ethanol prior to being dissolved in a minimal volume of DEPC-treated water.

 8. Total RNA quality was checked using the RNA 6000 Nano Assay, and analysed on an Agilent 2100 Bioanalyser (Agilent Technologies). RNA was quantified using the Nanodrop ultra low volume spectrophotometer (Nanodrop Technologies).""" .

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      a       isa:OntologyEntry .

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isa:hasProtocolApplication
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:FV3672
      a       isa:FactorValue .

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      a       isa:Material ;
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:OE3586
      a       isa:OntologyEntry .

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      a       isa:FactorValue .

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      a       isa:Material ;
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      isa:hasData :D3725 ;
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      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC16_Nitrogen_0.20_Internal_1_1.txt" ;
      dcterms:title "JIC16_Nitrogen_0.20_Internal_1_1.txt" .

:FV2968
      a       isa:FactorValue .

:OE2990
      a       isa:OntologyEntry .

:FV3708
      a       isa:FactorValue .

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      a       isa:Assay .

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              :PA3934 ;
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              :PA2934 ;
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      isa:hasMaterial :M3061 ;
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      dcterms:title "JIC91_Ethanol_0.07_External_1_1.txt" .

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      a       isa:Assay .

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              :PA3933 ;
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              :PA2936 ;
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      a       isa:OntologyEntry .

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              :PA2384 ;
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      a       isa:MaterialProcessing ;
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              :PA3932 ;
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:A1194
      a       isa:Assay .

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      a       isa:Data ;
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      isa:hasFactorValue :FV3624 , :FV3623 ;
      dcterms:title "SCAN:MEXP:3922" .

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      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.69" ;
      isa:hasInputNode :MN2096 ;
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      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.6" ;
      isa:hasInputNode :MN2081 ;
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      isa:hasProtocolApplication
              :PA2938 ;
      isa:hasStudy :S1 .

:DAN638
      a       isa:DataAcquisition ;
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      isa:hasStudy :S2 .

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      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
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      isa:hasProtocolApplication
              :PA2381 ;
      isa:hasStudy :S2 .

:M2368
      a       isa:Material ;
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:MN1344
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.18:out:0" ;
      isa:hasMaterial :M2364 ;
      isa:hasStudy :S2 .

:FV3709
      a       isa:FactorValue .

:PA3881
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:PA2494
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:D3006
      a       isa:Data ;
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      dcterms:title "JIC26_Phosphate_0.20_Internal_2_1.txt" .

:A1193
      a       isa:Assay .

:MN1001
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.41" ;
      isa:hasInputNode :MN1646 ;
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      isa:hasStudy :S2 .

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      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.2.4.0" ;
      isa:hasInputNode :MN1397 ;
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      isa:hasProtocolApplication
              :PA2940 ;
      isa:hasStudy :S2 .

:MN967
      a       isa:MaterialProcessing ;
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      a       isa:MaterialNode ;
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      isa:hasStudy :S2 .

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      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.49:out:0" ;
      isa:hasMaterial :M2348 ;
      isa:hasStudy :S2 .

:D3560
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3926" ;
      dcterms:title "SCAN:MEXP:3926" .

:MN56
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.0.2.51" ;
      isa:hasInputNode :MN1362 ;
      isa:hasOutputNode :MN1996 ;
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              :PA2378 ;
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:M2779
      a       isa:Material ;
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:M2964
      a       isa:Material ;
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:FV3666
      a       isa:FactorValue .

:MN1637
      a       isa:MaterialNode ;
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      a       isa:MaterialProcessing ;
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              :PA3939 ;
      isa:hasStudy :S2 .

:MN969
      a       isa:MaterialProcessing ;
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      isa:hasInputNode :MN1671 ;
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:A1248
      a       isa:Assay .

:OE3379
      a       isa:OntologyEntry .

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              :PA3938 ;
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              :PA2375 ;
      isa:hasStudy :S2 .

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:FV3703
      a       isa:FactorValue .

:FV3667
      a       isa:FactorValue .

:DAN636
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      isa:hasOutputNode :DN1811 ;
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:MN2114
      a       isa:MaterialNode ;
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      isa:hasMaterial :M2301 ;
      isa:hasStudy :S2 .

:DN2135
      a       isa:DataNode ;
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      isa:hasData :D3222 ;
      isa:hasStudy :S2 .

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      a       isa:Data ;
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:OE2646
      a       isa:OntologyEntry .

:DPN166
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      isa:hasInputNode :DN1328 ;
      isa:hasOutputNode :DN1501 ;
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:A1249
      a       isa:Assay .

:PA3911
      a       isa:ProtocolApplication ;
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:DPN382
      a       isa:DataProcessing ;
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      isa:hasInputNode :DN1592 ;
      isa:hasOutputNode :DN1379 ;
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:DN1936
      a       isa:DataNode ;
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      isa:hasData :D3535 ;
      isa:hasStudy :S2 .

:PA3544
      a       isa:ProtocolApplication ;
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:D3114
      a       isa:Data ;
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:A1199
      a       isa:Assay .

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      a       isa:MaterialNode ;
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      isa:hasMaterial :M2671 ;
      isa:hasStudy :S2 .

:OE2992
      a       isa:OntologyEntry .

:D3009
      a       isa:Data ;
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:OE3377
      a       isa:OntologyEntry .

:MN54
      a       isa:MaterialProcessing ;
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              :PA2372 ;
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:MN1569
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:M2962
      a       isa:Material ;
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:D3839
      a       isa:Data ;
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:A1246
      a       isa:Assay .

:DAN634
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:DN2134
      a       isa:DataNode ;
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:D3117
      a       isa:Data ;
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:MN1341
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:A1198
      a       isa:Assay .

:FV3308
      a       isa:FactorValue .

:MN1568
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              :PA3936 ;
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:PA2491
      a       isa:ProtocolApplication ;
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:D3222
      a       isa:Data ;
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:MN2194
      a       isa:MaterialNode ;
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:DPN169
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:FV3812
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:DAN363
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isa:GraphElement
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:OE3653
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:D3080
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:OE3097
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:MN771
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:FV3302
      a       isa:FactorValue .

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:MN961
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:ISA_3976
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:PA3774
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:OE3731
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:DN1439
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:D3551
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_raw_data:a_transcriptome.SCAN:MEXP:3917" ;
      dcterms:title "SCAN:MEXP:3917" .

:D3004
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC100_GlucoseO2_0.07_External_1_1.txt" ;
      dcterms:title "JIC100_GlucoseO2_0.07_External_1_1.txt" .

:DPN737
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.31" ;
      isa:hasInputNode :DN2118 ;
      isa:hasOutputNode :DN1347 ;
      isa:hasStudy :S2 .

:M2290
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.C-0.2-aliquot2" .

:MN770
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.106" ;
      isa:hasInputNode :MN1441 ;
      isa:hasOutputNode :MN1491 ;
      isa:hasProtocolApplication
              :PA3781 ;
      isa:hasStudy :S2 .

:M3870
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.C-0.07-aliquot6" .

:FV3301
      a       isa:FactorValue .

:DPN675
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.14" ;
      isa:hasInputNode :DN1753 ;
      isa:hasOutputNode :DN1628 ;
      isa:hasStudy :S2 .

:M2412
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:S-0.1-aliquot11" .

:DAN890
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.6.7.3" ;
      isa:hasInputNode :MN1866 ;
      isa:hasOutputNode :DN1905 ;
      isa:hasStudy :S1 .

:MN178
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.24" ;
      isa:hasInputNode :MN2006 ;
      isa:hasOutputNode :MN1770 ;
      isa:hasProtocolApplication
              :PA2725 ;
      isa:hasStudy :S2 .

:MN1560
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.2.4.9:out:0" ;
      isa:hasMaterial :M2547 ;
      isa:hasStudy :S1 .

:MN2089
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.35:out:0" ;
      isa:hasMaterial :M3413 ;
      isa:hasStudy :S2 .

:DPN161
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.7.8.6" ;
      isa:hasInputNode :DN1585 ;
      isa:hasOutputNode :DN1399 ;
      isa:hasStudy :S2 .

isa:Annotatable
      rdfs:subClassOf isa:Identifiable .

:MN962
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.65" ;
      isa:hasInputNode :MN1967 ;
      isa:hasOutputNode :MN1798 ;
      isa:hasStudy :S2 .

:MN773
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.43" ;
      isa:hasInputNode :MN1340 ;
      isa:hasOutputNode :MN1506 ;
      isa:hasStudy :S2 .

:ISA_3979
      a       foaf:Person , isa:Contact ;
      foaf:family_name "Juan"^^xsd:string ;
      foaf:givenname "Castrillo"^^xsd:string .

:MN548
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.9" ;
      isa:hasInputNode :MN2117 ;
      isa:hasOutputNode :MN1630 ;
      isa:hasProtocolApplication
              :PA3402 ;
      isa:hasStudy :S2 .

:D3001
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:ms_spec_raw_data:a_metabolome.JIC25_Phosphate_0.20_Internal_1_1.txt" ;
      dcterms:title "JIC25_Phosphate_0.20_Internal_1_1.txt" .

:D3565
      a       isa:Data ;
      isa:hasAccessionID "BII-S-1:microarray_normalized_data:a_transcriptome.SCAN:MEXP:3947" ;
      isa:hasFactorValue :FV3568 , :FV3567 ;
      dcterms:title "SCAN:MEXP:3947" .

:PA3424
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1112 .

:DN1356
      a       isa:DataNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.75:out:0" ;
      isa:hasData :D3173 ;
      isa:hasStudy :S2 .

:DAN367
      a       isa:DataAcquisition ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.4.5.57" ;
      isa:hasInputNode :MN2173 ;
      isa:hasOutputNode :DN1744 ;
      isa:hasStudy :S2 .

:M2293
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:extract:a_transcriptome.S-0.1-aliquot1" .

:M2415
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.2-aliquot11" .

:FV3300
      a       isa:FactorValue .

:DPN678
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.13" ;
      isa:hasInputNode :DN1811 ;
      isa:hasOutputNode :DN1698 ;
      isa:hasStudy :S2 .

:M3895
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.G-0.1-aliquot6" .

:M3658
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:labelled_extract:a_metabolome.S-0.2-aliquot7" .

:DAN418
      a       isa:DataAcquisition ;
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      isa:hasInputNode :MN2124 ;
      isa:hasOutputNode :DN1453 ;
      isa:hasStudy :S2 .

:MN810
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.3.4.58" ;
      isa:hasInputNode :MN1845 ;
      isa:hasOutputNode :MN1675 ;
      isa:hasStudy :S2 .

:PA2274
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1105 .

:DPN160
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_proteome.7.8.7" ;
      isa:hasInputNode :DN1585 ;
      isa:hasOutputNode :DN1399 ;
      isa:hasStudy :S2 .

:PA3772
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1111 .

:ISA_3978
      a       foaf:Person , isa:Contact ;
      foaf:family_name "Leo"^^xsd:string ;
      foaf:givenname "Zeef"^^xsd:string .

:MN963
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.64" ;
      isa:hasInputNode :MN1967 ;
      isa:hasOutputNode :MN1798 ;
      isa:hasStudy :S2 .

:DPN388
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.5.6.55" ;
      isa:hasInputNode :DN1532 ;
      isa:hasOutputNode :DN1379 ;
      isa:hasStudy :S2 .

:MN772
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:s_BII-S-1.0.2.107" ;
      isa:hasInputNode :MN1441 ;
      isa:hasOutputNode :MN1908 ;
      isa:hasProtocolApplication
              :PA3783 ;
      isa:hasStudy :S2 .

:DPN739
      a       isa:DataProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.7.8.32" ;
      isa:hasInputNode :DN2051 ;
      isa:hasOutputNode :DN1345 ;
      isa:hasStudy :S2 .

:MN549
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.0.2.8" ;
      isa:hasInputNode :MN1386 ;
      isa:hasOutputNode :MN1912 ;
      isa:hasProtocolApplication
              :PA3404 ;
      isa:hasStudy :S2 .

:MN1348
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-1:proc:a_metabolome.2.3.13:out:0" ;
      isa:hasMaterial :M3644 ;
      isa:hasStudy :S2 .

:MN179
      a       isa:MaterialProcessing ;
      isa:hasAccessionID "BII-S-1:proc:a_transcriptome.4.6.25" ;
      isa:hasInputNode :MN1540 ;
      isa:hasOutputNode :MN1366 ;
      isa:hasProtocolApplication
              :PA2727 ;
      isa:hasStudy :S2 .

:M2364
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:sample:C-0.1-aliquot9" .

:MN1349
      a       isa:MaterialNode ;
      isa:hasAccessionID "BII-S-2:proc:a_microarray.0.2.13:out:0" ;
      isa:hasMaterial :M2466 ;
      isa:hasStudy :S1 .

:PA2405
      a       isa:ProtocolApplication ;
      isa:appliesProtocol :P_1109 .

:M3894
      a       isa:Material ;
      isa:hasAccessionID "BII-S-1:source:culture16" .

: owl:sameAs :I1115 .