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+%dl#similarity{ :style => "display: none;" }
+ %dt
+ Similarity
+ (
+ = hide_link "#similarity"
+ )
+ %dd
+ %code lazar
+ calculates
+ %em activity specific
+ similarities based on the presence of statistically
+ = toggle_link "#significant_fragments", "significant fragments"
+ This procedure will
+ %ul
+ %li consider only those parts of a chemical structure that are relevant for a particular endpoint
+ %li ignore inert parts of the structure
+ %li lead to different similarities, depending on the toxic endpoint
+ Similarities of 1 may be encountered even for structurally dissimilar compounds, because inert parts are ignored.
+