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%dl#similarity{ :style => "display: none;" }
%dt
Similarity
(
= hide_link "#similarity"
)
%dd
%code lazar
calculates
%em activity specific
similarities based on the presence of statistically
= toggle_link "#significant_fragments", "significant fragments"
This procedure will
%ul
%li consider only those parts of a chemical structure that are relevant for a particular endpoint
%li ignore inert parts of the structure
%li lead to different similarities, depending on the toxic endpoint
Similarities of 1 may be encountered even for structurally dissimilar compounds, because inert parts are ignored.
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