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authorgebele <gebele@in-silico.ch>2017-02-07 14:05:17 +0000
committergebele <gebele@in-silico.ch>2017-02-07 14:05:17 +0000
commitd8b69f89bf99a62aa15a2b828b63fe4ccfd8e9ad (patch)
tree28cf8bd689ba43d012cf678fde34ebeafdddf589
re-init
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diff --git a/README.md b/README.md
new file mode 100644
index 0000000..b62e6dd
--- /dev/null
+++ b/README.md
@@ -0,0 +1,6 @@
+# lazar-public-data
+
+- Public lazar datasets
+- Scripts to generate prediction models and crossvalidations
+
+`mongorestore --host 127.0.0.1` imports the database dump
diff --git a/classification/DSSTox_Carcinogenic_Potency_DBS_Mouse.csv b/classification/DSSTox_Carcinogenic_Potency_DBS_Mouse.csv
new file mode 100644
index 0000000..d1583c2
--- /dev/null
+++ b/classification/DSSTox_Carcinogenic_Potency_DBS_Mouse.csv
@@ -0,0 +1,978 @@
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diff --git a/classification/DSSTox_Carcinogenic_Potency_DBS_Mouse.json b/classification/DSSTox_Carcinogenic_Potency_DBS_Mouse.json
new file mode 100644
index 0000000..02113d4
--- /dev/null
+++ b/classification/DSSTox_Carcinogenic_Potency_DBS_Mouse.json
@@ -0,0 +1,5 @@
+{
+ "species": "Mouse",
+ "endpoint": "Carcinogenicity",
+ "source": "http://www.epa.gov/ncct/dsstox/sdf_cpdbas.html"
+}
diff --git a/classification/DSSTox_Carcinogenic_Potency_DBS_MultiCellCall.csv b/classification/DSSTox_Carcinogenic_Potency_DBS_MultiCellCall.csv
new file mode 100644
index 0000000..8f8bbf4
--- /dev/null
+++ b/classification/DSSTox_Carcinogenic_Potency_DBS_MultiCellCall.csv
@@ -0,0 +1,1120 @@
+STRUCTURE_SMILES,ActivityOutcome_CPDBAS_MultiCellCall
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diff --git a/classification/DSSTox_Carcinogenic_Potency_DBS_MultiCellCall.json b/classification/DSSTox_Carcinogenic_Potency_DBS_MultiCellCall.json
new file mode 100644
index 0000000..5c725db
--- /dev/null
+++ b/classification/DSSTox_Carcinogenic_Potency_DBS_MultiCellCall.json
@@ -0,0 +1,4 @@
+{ "species": "Rodents (multiple species/sites)",
+ "endpoint": "Carcinogenicity",
+ "source": "http://www.epa.gov/ncct/dsstox/sdf_cpdbas.html"
+}
diff --git a/classification/DSSTox_Carcinogenic_Potency_DBS_Rat.csv b/classification/DSSTox_Carcinogenic_Potency_DBS_Rat.csv
new file mode 100644
index 0000000..5136286
--- /dev/null
+++ b/classification/DSSTox_Carcinogenic_Potency_DBS_Rat.csv
@@ -0,0 +1,1198 @@
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+CC(C)(CO)CCCCCCC(C)(C)CO,inactive
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+C=CCO,inactive
+ClC(C(Cl)Cl)(Cl)Cl,inactive
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+C1(CCCCC1[N+]).O=S(=O)([O-])O,inactive
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+O(S(=O)(=O)C)CCCCOS(=O)(C)=O,inactive
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+OC(OC(O)CC)CC,inactive
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+CC(C)NCC(O)COc1ccc(cc1)NC(C)=O,inactive
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+CCN(CC)C(=O)C1=CC=CC(C)=C1,inactive
+C1(CCNC(NC(N)=N)=N)=CC=CC=C1.[H]Cl,inactive
+C1CCNCC1,inactive
+NCCS(O)(=O)=O,inactive
+C1(CCN=C=S)=CC=CC=C1,inactive
+C1(CSCCNC(NC)=NC#N)=C(C)NC=N1,inactive
+O=[Cr]O[Cr]=O,inactive
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+S=C(S[Pb]SC(N(C)C)=S)N(C)C,inactive
+O=[N+](C1=C(C(=CC(=C1)C(F)(F)F)[N+](=O)[O-])N(CCC)CCC)[O-],inactive
+N=C\2/N=C3/O[C@H]1[C@H](O)[C@@H](CO)O[C@H]1N3/C=C/2,inactive
+O=[N+](C1=CC(=C(C=C1)C(=O)O)N)[O-],inactive
+O=[N+](C1=C2C(=CC=C1)C=CC=C2)[O-],inactive
+ClC1/C=C\C2C1C3(Cl)C(/Cl)=C(/Cl)C2(Cl)C3(Cl)Cl,inactive
+C1(C(=CC=C(C=1)C)N)C.[H]Cl,inactive
+ClC1=C(C(=C(C(=C1Cl)Cl)Cl)Cl)[N+](=O)[O-],inactive
+O=NN1CN(C2)CN(N=O)CN2C1,inactive
+CC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-],inactive
+C1(=CC=C(N)C=C1)C.[H]Cl,inactive
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+O=[N+](C1=CC=C(C=C1)N)[O-],inactive
+O=C(C1=C(C=CC=C1)C(=O)OCC=C)OCC=C,inactive
+ClC1(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl,inactive
+O=[N+](C1=CC=C(C=C1)Cl)[O-],inactive
+O=S(C1=CC=C2C(C=CC(O)=C2\N=N/C3=CC=C(S(=O)([O-])=O)C=C3)=C1)([O-])=O.[Na+].[Na+],inactive
+O=[N+](C1=CC(=C(C=C1)N)N)[O-],inactive
+NC1=C(C=C(C=C1)N)[N+](=O)[O-],inactive
+ClCC(=O)C1=CC=C(NC(=O)C)C=C1,inactive
+ClC(=C(C1=CC=C(C=C1)OC)C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC,inactive
+[Na+].O=C([O-])[C@@H](N)CCC(O)=O,inactive
+O=S1(=O)CC=CC1,inactive
+O[C@H]([C@H](O)CNCCCl)[C@H](O)[C@H](O)CNCCCl,inactive
+[Ti+2](C1=CC=CC1)C2(=CC=CC2).[Cl-].[Cl-],inactive
+O[C@@H](CO)[C@@H](O1)C(OCC)=C(O)C1=O,inactive
+OC(=O)[C@@H](N)CSCC,inactive
+CC(OC(=O)OC1CCCCC1)OC(=O)c5cccc6nc(OCC)n(Cc2ccc(cc2)c3ccccc3C\4=N\N=N/N/4)c56,inactive
+O[C@@H]1C2[C@@]34C5=C(C=CC(=C5O2)OC)CC(C3C=C1)N(C)CC4,inactive
+NC1=NC(N)=NC(C2=CC(Cl)=CC=C2Cl)=N1.O=C(O)/C=C\C(O)=O,inactive
+C/C=C/C1=CC=C(C=C1)OC,inactive
+O=[C@]([C@@H]1C[C@@H](O)CN1N=O)O,inactive
+C(C(F)(Cl)Cl)(F)(F)Cl,inactive
+C1(C(COCCOC(=O)CCCCCCCC=CCCCCCCCC)OCCO)OC(OCCO)CC1OCCO,inactive
+O=[Bi]Cl,inactive
+O=C(O[C@H](CC)[C@](O)(C)[C@H](O)[C@@H](C)C2=O)[C@H](C)[C@@H](O[C@H]3C[C@](OC)(C)[C@@H](O)[C@H](C)O3)[C@H](C)[C@H]([C@@](O)(C)C[C@H]2C)O[C@H]1[C@H](O)[C@@H]([N@H+](C)C)C[C@@H](C)O1.[O-]C(CCCCCCCCCCCCCCCCC)=O,inactive
+O[Sn](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3,inactive
+O=[As](O)(O)[O-].[Na+],inactive
+CC(C=NOC(=O)NC)(SC)C,inactive
diff --git a/classification/DSSTox_Carcinogenic_Potency_DBS_Rat.json b/classification/DSSTox_Carcinogenic_Potency_DBS_Rat.json
new file mode 100644
index 0000000..5ea1e76
--- /dev/null
+++ b/classification/DSSTox_Carcinogenic_Potency_DBS_Rat.json
@@ -0,0 +1,3 @@
+{ "species": "Rat",
+"endpoint": "Carcinogenicity",
+"source": "http://www.epa.gov/ncct/dsstox/sdf_cpdbas.html" }
diff --git a/classification/blood-brain-barrier.csv b/classification/blood-brain-barrier.csv
new file mode 100644
index 0000000..a8c0587
--- /dev/null
+++ b/classification/blood-brain-barrier.csv
@@ -0,0 +1,416 @@
+SMILES,"Blood-Brain-Barrier Penetration"
+c12c(c(ccc1)Cl)C(N(Cc1n2cnc1c1nc(on1)[C@](CO)(C)O)C)=O,nonpenetrating
+NCCc1cn2c(n1)cccc2,nonpenetrating
+CCCN(CCC)CCc1ccc(c2c1CC(N2)=C)O,penetrating
+c1(c2c(cc(F)cc2)on1)C1CCN(CCc2c(n3c([C@@H](CCC3)O)nc2C)=O)CC1,penetrating
+c12c(C(c3ccccc3)=NCc3n1c(nn3)C)cc(Cl)cc2,penetrating
+C1(\c2c(CCc3c1cccc3)cccc2)=C\CCN(C)C,penetrating
+c12c(ncnc1O)[nH]nc2,penetrating
+n1(c2ccccc2)n(c(C)cc1=O)C,penetrating
+c1(c(cccc1)OC(C)=O)C(O)=O,penetrating
+N(C(NCCCl)=O)(CCCl)N=O,penetrating
+c12c(n(c(=O)n(c1=O)C)C)ncn2C,penetrating
+N1(c2c(cccc2)C=Cc2c1cccc2)C(N)=O,penetrating
+c1(N(CCCl)CCCl)ccc(CCCC(O)=O)cc1,nonpenetrating
+N1(c2c(Sc3c1cccc3)ccc(c2)Cl)CCCN(C)C,penetrating
+c1(c([nH]cn1)C)CSCCN\C(=[NH]\C#N)NC,nonpenetrating
+c1(NC=2NCCN2)c(cccc1Cl)Cl,penetrating
+c12[C@]34[C@@H]5[C@H]([N@@](C)CC4)Cc2ccc(c1O[C@H]3[C@@H](O)C=C5)OC,penetrating
+N1(c2c(CCc3c1cccc3)cccc2)CCCNC,penetrating
+n1(c2c(c(ncn2)O)nc1)[C@@H]1O[C@H](CO)CC1,nonpenetrating
+n1(c2c(cc(Cl)cc2)[nH]c1=O)C1CCN(CCCn2c3c(cccc3)[nH]c2=O)CC1,penetrating
+N1([C@@H](c2ccc(Cl)cc2)c2ccccc2)CCN(CCOCCO)CC1,penetrating
+c1([C@@H](C(O)=O)C)ccc(CC(C)C)cc1,penetrating
+c1c(c(ncc1)CCCCNc1nc(c(c[nH]1)Cc1ccc(nc1)C)=O)OC,nonpenetrating
+N1(c2c(CCc3c1cccc3)cccc2)CCCN(C)C,penetrating
+c12c(c(CC(O)=O)c(n1C(c1ccc(Cl)cc1)=O)C)cc(OC)cc2,nonpenetrating
+c12c(C(N(Cc3n1cnc3c1noc(n1)C(C)C)C)=O)c(ccc2)Cl,penetrating
+CN(C)Cc1ccc(CSCCNc2nc(=O)c(Cc3ccc(C)nc3)c[nH]2)o1,nonpenetrating
+N(c1ccccn1)(Cc1ccc(OC)cc1)CCN(C)C,penetrating
+N12[C@H](c3c(cccc3)Cc3c1cccc3)C[N@](C)CC2,penetrating
+c12c(C(c3c(cccc3)F)=NCc3n1c(nc3)C)cc(Cl)cc2,penetrating
+N12[C@H](c3c(cccc3)Cc3c1nccc3)C[N@](C)CC2,penetrating
+N1(c2c(NC(c3c1nccc3)=O)c(ccn2)C)C1CC1,penetrating
+C1NCCN(C1)c1ccc(c(n1)Cl)C(F)(F)F,penetrating
+c1c2c(cc(c1)Cl)[C@@H]1[C@H](c3ccccc3O2)CNC1,penetrating
+c1c2c(ccc1)[C@@]1([C@@H](c3cccc(c3O2)C)CNCC1)O,penetrating
+c1ccc(c(c1)[C@H](CC=C)N)c1c2c(on1)cccc2,penetrating
+c1c2c(ccc1)[C@@]1([C@@H](c3cccc(c3O2)C)C[N@](CC1)C)O,penetrating
+c1c2c(cc(c1)Cl)[C@@H]1[C@H](c3ccccc3O2)CN(C1)C,penetrating
+c12C(c3ccccc3)=N[C@H](O)C(Nc1ccc(c2)Cl)=O,penetrating
+c1(oc([CH2+]SCCN\C(=C\[N+](=O)[O-])NC)cc1)CN(C)C,nonpenetrating
+c1(c2c(cc(F)cc2)on1)C1CCN(CCc2c(n3c(CCCC3)nc2C)=O)CC1,penetrating
+C1(C(NC(=[O-])NC1=O)=O)([C@H](CCC)C)[CH-]C,penetrating
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+N1(c2c(Sc3c1cccc3)cccc2)CCCN(C)C,penetrating
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+C1[C@H]2[C@H]3[C@@H](C4=C(CC(=O)CC4)C[C@H]3C)CC[C@@]2([C@@](C#C)(O)C1)C,penetrating
+c1(nc(NC(N)=[NH2])sc1)CSCCN\C(=[NH]\C#N)NC,penetrating
+C(CCC)(CCC)C(=O)[O-],penetrating
+c1([C@](CCC[N@](CCc2cc(c(OC)cc2)OC)C)(C(C)C)C#N)cc(c(OC)cc1)OC,penetrating
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+n12c3c(C(c4c(cccc4)F)=NCc1cnc2CO)cc(Cl)cc3,penetrating
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+C([C@H](OC(F)F)Cl)(F)(F)F,penetrating
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+C1([C@](C(NC(N1C)=[O-])=O)([C@@H](C#CCC)C)CC=C)=[O-],penetrating
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+N1(c2c(Sc3c1cccc3)ccc(c2)SC)CC[C@H]1NCCCC1,penetrating
+C1N(CCN(C1)c1cc(ccn1)C(F)(F)F)CCCCN1C(CCC1)=O,penetrating
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+c1c2c(sc1)C(N(Cc1n2cnc1C(=O)OC(C)(C)C)C)=O,penetrating
+C1C(Nc2c1c(ccc2)CCN(CCC)CCC)=O,penetrating
+C1C(Nc2c1c(ccc2O)CCN(CCC)CCC)=O,penetrating
+N(C(=O)c1c(O)cccc1)CC(=O)O,penetrating
+C[N@@]1CCCC[C@H]1CCN1c2ccccc2Sc2ccc(cc12)S(C)(=O)=O,penetrating
+C([C@@H](F)Br)C(F)(F)F,penetrating
+c12c(c([nH]c(n1C)=O)=O)n(C)cn2,penetrating
+C1(C(C(NC(N1)=S)=O)([C@@H](CCC)C)CC)=O,penetrating
+c1(ccccc1)C,penetrating
+c12c(C(c3c(cccc3)Cl)=NCc3n1c(nn3)C)cc(Cl)cc2,penetrating
+c12N(c3c(cccc3)Sc1ccc(c2)C(F)(F)F)CCCN1CCN(C)CC1,penetrating
+C(=C\Cl)(\Cl)Cl,penetrating
+C(Cl)(Cl)Cl,penetrating
+c1c(nccc1)CCNC,penetrating
+c1c(nccc1)CCN(C)C,penetrating
+n1c(scc1)CCN,penetrating
+n1c(scc1c1ccccc1)CCN,nonpenetrating
+c1c(nc2n1cccc2)CCN,nonpenetrating
+n1([C@H]2C[C@H](N=[N+]=N)[C@H](O2)CO)c([nH]c(=O)c([cH+]1)C)=O,penetrating
+c1c(cccc1C)C,penetrating
+c1(c(cccc1)C)C,penetrating
+c1(ccc(C)cc1)C,penetrating
+CC(C)O,penetrating
+c12[C@@H]3[C@@H](c4c(cccc4)N(c1cccc2)C(N)=O)O3,penetrating
+c12c(nc(c(c1C(N[C@@H](CC)c1ccccc1)=O)C)c1ccccc1)cccc2,penetrating
+c1cc(ccc1CCCC(OC(C)(C)C)=O)N(CCCl)CCCl,penetrating
+C(=C)(Cl)(Cl)Cl,penetrating
+c1(ncccc1NC(C)C)N1CCN(C(c2cc3cc(NS(C)(=O)=O)ccc3[nH]2)=O)CC1,nonpenetrating
+C(c1ccccc1)(c1ccccc1)OC1CCN(CCCC(c2ccc(C(C)(C)C)cc2)=O)CC1,nonpenetrating
+N1(c2c(NC(c3c1cccc3)=O)cccn2)C(CN1CCN(C)CC1)=O,penetrating
+c12c(Sc3c(N1C[C@@H](N(C)C)C)cccc3)cccc2,penetrating
+s1cc(CSCCN\C(NC)=[NH]\C#N)nc1\[NH]=C(\N)N,penetrating
+c1cc(c2nc(sc2)CCN)ccc1,nonpenetrating
+c1cc(CCNC)ncc1,penetrating
+c1cc(CCN(C)C)ncc1,penetrating
+s1c(ncc1)CCN,penetrating
+c1nc(C2CCN(CC2)C(NC2CCCCC2)=S)c[nH]1,penetrating
+c1ccc2Oc3c(cc(cc3)Cl)[C@@H]3[C@@H](c2c1)C[N@](CC3)C,penetrating
+c1c(Cl)nc(N2CCN(CCCCN3C(CCC3)=O)CC2)cc1C(F)(F)F,penetrating
+c1ccc2Oc3c(cc(cc3)Cl)[C@@H]3[C@@H](c2c1)CNCC3,penetrating
+c1c(c(ncc1)CSCCN\C(=[NH]\C#N)NCC)Br,nonpenetrating
+c1cc(ncc1)CSCCNc1c(cc[nH]1)[N+](=O)[O-],penetrating
+c1(cc(nc(c1C)C)C(SC(CNc1c(cc[nH]1)[N+](=O)[O-])(C)C)(C)C)C,penetrating
+n1c(csc1\[NH]=C(\N)N)c1ccccc1,penetrating
+n1c(csc1\[NH]=C(\N)N)c1cccc(c1)N,nonpenetrating
+n1c(csc1\[NH]=C(\N)N)c1cccc(c1)NC(C)=O,nonpenetrating
+n1c(csc1\[NH]=C(\N)N)c1cccc(c1)N\C(NC)=[NH]\C#N,nonpenetrating
+s1cc(nc1\[NH]=C(\N)N)C,penetrating
+c1(c(oc(c1C)C(N(C(C)(N)C)C(N)(C)C)(C)C)C)C.C[NH+]O.[OH-],penetrating
+[NH]C(CC(C)C([N@@](C(C)(C)C)C(N)(C)N)(C)C)c1c(c(c[nH+][o+]1)C)[O-],penetrating
+C1CN(CCC1)Cc1cccc(c1)OCCCNC(=O)C,penetrating
+C1CN(CCC1)Cc1cccc(c1)OCCCNC(=O)c1ccccc1,penetrating
+C1CN(CCC1)Cc1cccc(c1)OCCCO,penetrating
+C1CN(CCC1)Cc1cccc(c1)OCCCNc1ncccc1,penetrating
+C1CN(CCC1)Cc1cccc(c1)OCCCNc1nccs1,penetrating
+C1CN(CCC1)Cc1cccc(c1)OCCCNc1nc2c(o1)cccc2,penetrating
+c1c(oc(c1)CN(C)C)CSCCNc1nc(c(c[nH]1)Cc1cc2c(cc1)cccc2)=O,nonpenetrating
+CN(C)Cc1oc(cc1)CSCCNC=1NC=C(CN1)Cc1cnc(cc1)C,nonpenetrating
+c1(nccc(c1)c1nc([nH]n1)N)N(C)C,nonpenetrating
+n1(c(c2nc[nH]c2n(c1=O)C)=O)C,penetrating
+c1c2CCOc2c(cc1OC)CN[C@@H]1CCCN[C@H]1c1ccccc1,penetrating
+c1(cc(N\C(=[NH]\c2cccc(c2)CC)C)ccc1)CC,penetrating
+c1(c(cc2n(ncc2c1)CCN)Cl)Cl,penetrating
+c12c(n([C@@H]3C[C@H](CO)C=C3)cn2)nc(N)nc1NC1CC1,penetrating
+c1(c(cc(NC(CCC)=O)cc1)C(C)=O)OC[C@@H](CNC(C)C)O,penetrating
+c12c(ncn1COCCO)c([nH]c(n2)N)=O,penetrating
+c12c(nc([nH]1)NC(OC)=O)cc(SCCC)cc2,penetrating
+C12(CC3CC(C1)CC(C2)C3)N,penetrating
+c1(ccccc1)C[C@H](C)N,penetrating
+S(CCNCCCN)P(O)(O)=O,nonpenetrating
+O([C@H]1[C@@H](C[C@H](N)[C@H]([C@@H]1O)O[C@H]1O[C@@H]([C@@H](O)[C@@H]([C@H]1O)O)CN)NC([C@H](CCN)O)=O)[C@H]1O[C@@H]([C@@H](O)[C@@H]([C@H]1O)N)CO,penetrating
+c1(c(cc(N)cc1)O)C(O)=O,nonpenetrating
+n1([C@@H]2O[C@H](CO)[C@H]([C@H]2O)O)c(nc(N)cc1)=O,penetrating
+c1(c(nc[nH]1)C(N)=O)\N=N\N(C)C,penetrating
+c12c([C@H](C[C@@](C2)(C(C)=O)O)O[C@H]2C[C@@H]([C@H](O)[C@@H](O2)C)N)c(c2C(c3c(cccc3C(c2c1O)=O)OC)=O)O,nonpenetrating
+C1[C@@H]2[C@](C(=C3C(c4c(ccc(c4[C@H]([C@@H]13)O)Cl)O)=O)O)(C(C(C(N)=O)=C([C@H]2N(C)C)O)=O)O,nonpenetrating
+Clc1ccc2NC(=O)CC(=O)N(c3ccccc3)c2c1,penetrating
+C=1(c2c(NC(CN1)=O)ccc(c2)Cl)c1ccccc1,penetrating
+N1(c2c(Sc3c1cccc3)cccc2)CCCNC,penetrating
+N1(C[C@@H](N2CC(NC(C2)=O)=O)C)CC(NC(C1)=O)=O,nonpenetrating
+c12[C@@]34[C@@H]([C@H]([N@@](C)CC3)Cc1ccc(c2)OC)CCCC4,penetrating
+N12[C@]([C@@H]3CCCN3C([C@@H]1Cc1ccccc1)=O)(OC(NC([C@@H]1C[C@@H]3c4c5c(c[nH]c5ccc4)C[C@H]3[N@@](C1)C)=O)(C)C2=O)O,nonpenetrating
+N(C(SSC(N(CC)CC)=S)=S)(CC)CC,penetrating
+c12c([C@H](C[C@@](C2)(C(CO)=O)O)O[C@H]2C[C@@H]([C@H](O)[C@@H](O2)C)N)c(c2C(c3c(cccc3C(c2c1O)=O)OC)=O)O,nonpenetrating
+C=1([C@]2([C@H]([C@@H](C(O)=C(C2=O)C(N)=O)N(C)C)[C@H]([C@@H]2[C@H](c3cccc(c3C(C12)=O)O)C)O)O)O,penetrating
+c12[C@](C#CC3CC3)(OC(=O)Nc1ccc(c2)Cl)C(F)(F)F,nonpenetrating
+N1([C@@H](CCC1)C(O)=O)C([C@@H](N[C@@H](CCc1ccccc1)C(OCC)=O)C)=O,nonpenetrating
+c1(cc(c(O)cc1)O)[C@H](CNC)O,nonpenetrating
+c1(c(c(c(OCC(O)=O)cc1)Cl)Cl)C(C(CC)=C)=O,nonpenetrating
+N([C@H](CC)CO)CCN[C@H](CC)CO,nonpenetrating
+c1(cc(ncc1)CC)C(N)=S,penetrating
+C1([C@@](CC(=O)N1)(CC)C)=O,penetrating
+c12[C@H]([C@@H]3[C@H](COC3=O)[C@@H](c1cc1OCOc1c2)O[C@@H]1O[C@H]2[C@@H](O[C@H](C)OC2)[C@@H]([C@H]1O)O)c1cc(c(O)c(c1)OC)OC,nonpenetrating
+c1(nc(CSCC\C(=[NH]\S(N)(=O)=O)N)cs1)\[NH]=C(\N)N,penetrating
+c1(C(Cn2cncn2)(Cn2cncn2)O)c(cc(F)cc1)F,penetrating
+P(C(=O)O)(=O)(O)O,penetrating
+C1(CC(O)=O)(CCCCC1)CN,penetrating
+N12[C@@H]([C@@H](NC(c3c4c(ccc3OCC)cccc4)=O)[C-]2=O)SC([C@@H]1C(=O)O)(C)C,nonpenetrating
+c12c(c(c(C(O)=O)cn1CC)=O)ccc(n2)C,nonpenetrating
+C1[C@@H]2CCCC[C@@H]2C[N@](C[C@H]([C@@H](NC(c2c(c(ccc2)O)C)=O)CSc2ccccc2)O)[C@@H]1C(NC(C)(C)C)=O,nonpenetrating
+N1(c2c(Sc3c1cccc3)ccc(c2)SC)CC[C@H]1NCCCC1,nonpenetrating
+c12c([nH]c(n1)[S@@](Cc1c(c(c(C)cn1)OC)C)=O)ccc(c2)OC,nonpenetrating
+N12[C@@H]([C@@H](NC(c3c(c4ccccc4)noc3C)=O)[C-]2=O)SC([C@@H]1C(=O)O)(C)C,nonpenetrating
+c1(ccc(O)cc1)NC(C)=O,penetrating
+c12[C@]3([C@H]([C@H]([N@@](C\C=C(\C)C)CC3)Cc1ccc(c2)O)C)C,penetrating
+n1(c2c([C@@H](CNC=N2)O)nc1)[C@@H]1O[C@H](CO)C(C1)O,penetrating
+C1(c2ccccc2)(C(OCC)=O)CCN(C)CC1,penetrating
+c1(c(nc(N)cc1)N)\N=N\c1ccccc1,nonpenetrating
+C1(c2ccccc2)(C(NC(=O)NC1=O)=O)CC,penetrating
+N12[C@@H]([C@@H](NC(COc3ccccc3)=O)[C-]2=O)SC([C@@H]1C(=O)O)(C)C,nonpenetrating
+c12c([nH]cc2)cccc1OC[C@@H](CNC(C)C)O,penetrating
+c12c(C[C@@H]([C@@H](C([C@H]([C@@H](C)O)O)=O)OC)[C@@H](C1=O)OC1C[C@@H](O[C@H]3C[C@@H](O[C@H]4C[C@]([C@H](O)[C@H](O4)C)(C)O)[C@H](O)[C@H](O3)C)[C@H](O)[C@H](O1)C)cc1cc(O[C@H]3C[C@@H](O[C@H]4C[C@H]([C@H](O)[C@H](O4)C)O)[C@@H](O)[C@H](O3)C)c(c(c1c2O)O)C,penetrating
+C=12[C@@H]([C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)[C@H](C[C@@H](O)C1)OC([C@H](CC)C)=O,nonpenetrating
+c12[C@@H]3N(C(CN(C3)C(C3CCCCC3)=O)=O)CCc1cccc2,penetrating
+c1(S(N(CCC)CCC)(=O)=O)ccc(C(O)=O)cc1,nonpenetrating
+c1(Cc2c(nc(N)nc2)N)cc(c(OC)c(c1)OC)OC,penetrating
+c12c(ccc(CNc3cc(c(OC)c(c3)OC)OC)c1C)nc(N)nc2N,nonpenetrating
+C(CO)(CO)(CO)N,nonpenetrating
+c12n(c3c(cc(F)cc3)F)cc(C(O)=O)c(c1cc(F)c(n2)N1C[C@@H]2C(N)[C@H]2C1)=O,penetrating
+C(N)(N)=O,penetrating
+C=1(C2CCC(c3ccc(Cl)cc3)CC2)C(c2c(cccc2)C(C1O)=O)=O,nonpenetrating
+C1(C[C@@H]2N(C)[C@H](C1)CC2)OC([C@H](c1ccccc1)CO)=O,penetrating
+C(CCCCCCCC(O)=O)(O)=O,nonpenetrating
+O([C@H]1[C@@H]([C@@H](O[C@@H]2C[C@]([C@@H](O)[C@@H](O2)C)(OC)C)[C@@H](C(O[C@@H]([C@](C)(O)C([C@H]([N@@](C[C@@H](C[C@@]1(C)O)C)C)C)O)CC)=O)C)C)[C@H]1[C@@H]([C@H](C[C@H](O1)C)N(C)C)O,nonpenetrating
+C([C@@H]1C(N[C@@H](Cc2c[nH]cn2)C(N[C@@H](C(N[C@H](C(=O)N[C@H](C(N[C@@H](C(N[C@H](C(N1)=O)[C@H](CC)C)=O)CCCN)=O)CCCCNC([C@@H](NC([C@H](NC([C@@H](NC([C@H]1N=C([C@@H]([C@@H](CC)C)N)SC1)=O)CC(C)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CC(N)=O)=O)CC(O)=O)=O)=O)c1ccccc1,nonpenetrating
+C([N+](C)(C)C)[C@@H](OC(N)=O)C,nonpenetrating
+c1(c(cccc1)Br)C[N+](CC)(C)C,nonpenetrating
+N12[C@](C3N(CCC3)C([C@@H]2CC(C)C)=O)(O[C@](C1=O)(NC([C@@H]1C=C2c3c4c(c(Br)[nH]c4ccc3)C[C@H]2[N@@](C1)C)=O)C(C)C)O,nonpenetrating
+c12[C@]34[C@@]56[C@H]([N@@](CC7CC7)CC4)Cc2ccc(c1O[C@H]3[C@](OC)([C@H](C5)[C@](C(C)(C)C)(C)O)CC6)O,penetrating
+c1(C([C@@H](NC(C)(C)C)C)=O)cc(ccc1)Cl,penetrating
+O(S(C)(=O)=O)CCCCOS(C)(=O)=O,penetrating
+N12[C@@H]([C@@H](NC([C@H](c3ccccc3)C(=O)O)=O)[C-]2=O)SC([C@@H]1C(=O)O)(C)C,penetrating
+N(C(NCCCl)=O)(CCCl)N=O,penetrating
+N12[C@H]([C@@H](NC([C@H](C=3CC=CCC3)N)=O)C1=O)SCC(=C2C(O)=O)C,nonpenetrating
+C1([C@H]([C@H](NC(C(Cl)Cl)=O)CO)O)CCC([N+](=O)=[O-])C[CH+]1,penetrating
+c12c(nccc1N[C@@H](CCCN(CC)CC)C)cc(Cl)cc2,penetrating
+c12c(cc(Cl)c(c1)S(N)(=O)=O)N=CNS2(=O)=O,nonpenetrating
+c1(c(cc(N)c(c1)Cl)OC)C(N[C@@H]1[C@H](C[N@@](CCCOc2ccc(F)cc2)CC1)OC)=O,penetrating
+n1(c2c(c(nc(n2)Cl)N)nc1)[C@@H]1O[C@H](CO)C(C1)O,penetrating
+C(c1ccccc1)([C+]1CCCCC1)(C(O[C@@H]1C2CC[N+](C1)(C)CC2)=O)O,nonpenetrating
+n1(c2c(nc3c1cccc3)cc(Nc1ccc(Cl)cc1)c(\c2)=N/C(C)C)c1ccc(Cl)cc1,nonpenetrating
+N1(c2c(CCc3c1cccc3)ccc(c2)Cl)CCCN(C)C,penetrating
+c12c3c([C@@H](NC(C)=O)CCc2cc(c(c1OC)OC)OC)cc(=O)c(cc3)OC,nonpenetrating
+c12c(oc(C(=O)O)cc2=O)cccc1[O-]CC(COc1c2c(oc(C(=O)O)cc2=O)ccc1)O,nonpenetrating
+C1([C@@H](CON1)N)=O,penetrating
+[c-]12c(nc[n+]1COC(CO)CO)c(=[O-])[nH]c(n2)N,penetrating
+c12c(cc(Cl)c(c1)S(N)(=O)=O)NCNS2(=O)=O,nonpenetrating
+C(NO)(N)=O,penetrating
+[N+]1([C@H]2CC(OC([C@H](c3ccccc3)CO)=O)C[C@@H]1CC2)(C(C)C)C,nonpenetrating
+c1(C(NN)=O)ccncc1,penetrating
+c1([C@]2(O[C@H](COc3ccc(N4CCN(c5ccc(n6c(n([C@@H](CC)C)nc6)=O)cc5)CC4)cc3)CO2)Cn2cncn2)c(cc(Cl)cc1)Cl,nonpenetrating
+C1([C@@H](O[C@H]2O[C@@H]([C@@H](O)[C@@H]([C@H]2O)N)CO)[C@@H](C[C@@H]([C@H]1O[C@H]1O[C@@H]([C@@H](O)[C@@H]([C@H]1O)O)CN)N)N)O,nonpenetrating
+c1([C@@]2(O[C@@H](COc3ccc(N4CCN(C(C)=O)CC4)cc3)CO2)Cn2ccnc2)c(cc(Cl)cc1)Cl,nonpenetrating
+c1(cc(ccc1)[C@@H](C(O)=O)C)C(c1ccccc1)=O,penetrating
+n12c([C@H](C(O)=O)CC2)ccc1C(c1ccccc1)=O,nonpenetrating
+c12c3c(N4CCN(C)CC4)c(F)cc1c(c(C(O)=O)cn2[C@@H](C)CO3)=O,penetrating
+O[C@@H]([C@@H]([C@@H](CO)O)O)[C@@H](CO)O,nonpenetrating
+[C+](c1ccccc1)(c1ccccc1)(C(O[C@@H]1C[N+](CCC1)(C)C)=O)O,nonpenetrating
+c1(cc(ccc1)O)[C@H]([C@H](C)N)O,nonpenetrating
+c12c(ncc(n1)CN(c1ccc(C(N[C@@H](CCC(O)=O)C(O)=O)=O)cc1)C)nc(N)nc2N,nonpenetrating
+c1(ccc(CCOC)cc1)OC[C@@H](CNC(C)C)O,penetrating
+n1(c(cnc1C)[N+](=O)=[O-])CCO,penetrating
+C1=2[C@H]([C@H]3[C@]([C@@](C#CC)(O)CC3)(C)C[C@@H]1c1ccc(N(C)C)cc1)CCC=1C2CCC(C1)=O,nonpenetrating
+C1[C@@H]2[C@](C(=C3C(c4c(ccc(c4C[C@@H]13)N(C)C)O)=O)O)(C(C(C(N)=O)=C([C@H]2N(C)C)O)=O)O,penetrating
+c1(C(NCCN2CCOCC2)=O)ccc(Cl)cc1,penetrating
+C1(c2c(Oc3c1cccc3)cccc2)C(OCC[N+](C(C)C)(C(C)C)C)=O,nonpenetrating
+c1(cnccn1)C(N)=O,penetrating
+c1(OC(N(C)C)=O)c[n+](ccc1)C,penetrating
+c1(c2ccc(Cl)cc2)c(nc(N)nc1N)CC,penetrating
+c12c([C@H]([C@H]3[N@@]4C[C@H](C=C)[C@H](C3)CC4)O)ccnc1ccc(c2)OC,nonpenetrating
+n1([C@@H]2O[C@H](CO)[C@H]([C@H]2O)O)nc(C(N)=O)cn1,penetrating
+C([C@@H](C[C@@H]([C@H](Cc1ccccc1)NC(OCc1cncs1)=O)O)NC([C@@H](NC(N(Cc1nc(C(C)C)sc1)C)=O)C(C)C)=O)c1ccccc1,nonpenetrating
+C1[N@]([C@@H](C[C@@H]2CCCC[C@H]12)C(NC(C)(C)C)=O)C[C@H]([C@H](Cc1ccccc1)NC([C@@H](NC(c1nc2c(cccc2)cc1)=O)CC(N)=O)=O)O,nonpenetrating
+C(C(F)(F)F)(C(F)(F)F)OCF,penetrating
+C1(C(C(C(I)[C-](C1I)NC(C)=O)C(=O)O)I)NC(C)=O,nonpenetrating
+c1([C@@H](CNC(C)C)O)ccc(NS(C)(=O)=O)cc1,penetrating
+n1([C@@H]2O[C@H](CO)C=C2)c([nH]c(=O)c(c1)C)=O,penetrating
+O([C@@H]1[C@]([C@H](C)O[C@H]1O[C@H]1[C@@H]([C@H]([C@H](NC(N)=[NH2])[C@H]([C@@H]1O)O)O)NC(N)=[NH2])(C=O)O)[C@H]1[C@H]([C@@H]([C@@H](O)[C@@H](O1)CO)O)NC,nonpenetrating
+c1(S(Nc2ncccn2)(=O)=O)ccc(N)cc1,penetrating
+c1(S(Nc2c(c(C)no2)C)(=O)=O)ccc(N)cc1,penetrating
+c1(S(Nc2cc(C)on2)(=O)=O)ccc(N)cc1,penetrating
+c12c(c(c3CCCCc3n1)N)cccc2,penetrating
+C(=C(/c1ccccc1)CC)(\c1ccc(OCCN(C)C)cc1)c1ccccc1,penetrating
+c12C(c3ccccc3)=N[C@@H](O)C(N(c1ccc(c2)Cl)C)=O,penetrating
+N12[C@@H]([C@@H](NC([C@@H](c3ccsc3)C(=O)O)=O)C2=O)SC(C)(C)[C@@-]1C(=O)O,penetrating
+c12c(c(n3Cc4c(c3c2)nc2ccc(c(c2c4)CN(C)C)O)=O)COC([C@@]1(CC)O)=O,penetrating
+n1([C@@H]2O[C@H](CO)CC2)c(nc(N)cc1)=O,penetrating
+c12c(noc1cccc2)CS(N)(=O)=O,penetrating
+C(=O)(O)[C@@H]1[C@@H]2O[C@@](C[C@H]1O)(O)C[C@H](O)C[C@H](O)[C@H](O)CC[C@H](O)C[C@@H](O)CC(=O)O[C@H](C)[C@H](C)[C@@H]([C@H](C=CC=CC=CC=CC=CC=CC=C[C@@H](C2)O[C@@H]1[C@@H](O)[C@H](N)[C@H]([C@@H](O1)C)O)C)O,nonpenetrating
+C(=O)N1c2c(NC[C@H]1CNc1ccc(cc1)C(N[C@@H](CCC(=O)[O-])C([O-])=O)=O)nc(nc2O)N,penetrating
+[N-]12[C@H](SCC(=C1C(=O)[O-])C[n+]1ccccc1)[C@@H](C2=O)CC(\C(c1csc(n1)N)=N/OC(C(=O)O)(C)C)=O,penetrating
+c1cccc(c1)C[C@H](C)N,penetrating
+Nc1c(F)cnc(n1)O,penetrating
+C1CCCC2(C1)O[C@H](CO2)CNC(N)=[NH2],nonpenetrating
+O=C(N(CCCl)N=O)NC1CCCCC1,penetrating
+C(S([O-])(=O)=O)CS,nonpenetrating
+O1[C@H]([C@H](NC(N(N=O)C)=O)[C@H]([C@@H]([C@H]1CO)O)O)O,nonpenetrating
+O=C1[C@@H]2[C@H](c3c([C@@H]([C@H]2CO1)O[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]1O)O)O[C@H](OC2)c1cccs1)cc1c(c3)OCO1)c1cc(OC)c(c(c1)O)O,penetrating
+P(=S)(N1CC1)(N1CC1)N1CC1,penetrating
+c12cc3cc(c1O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1C[C@]([C@H]([C@@H](O1)C)O)(C)N)Oc1c(cc([C@H]([C@H](C(N[C@H](C(N[C@H]3C(N[C@H]3C(N[C@@H]([C@@H](c4cc(c(O2)cc4)Cl)O)C(N[C@H](C(O)=O)c2cc(O)cc(O)c2c2cc3ccc2O)=O)=O)=O)=O)CC(N)=O)=O)NC([C@H](NC)CC(C)C)=O)O)cc1)Cl,nonpenetrating
+n1cnc2c(c1N)ncn2[C@H]1[C@@H]([C@@H]([C@H](O1)CO)O)O,penetrating
+CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F,penetrating
+c1(NCCSCc2oc(cc2)CN(C)C)[nH]cc(c1N(=O)=O)Cc1ccccc1,penetrating
+c12c(C(N(Cc3n1cnc3c1noc(n1)C(CO)(CO)C)C)=O)c(ccc2)Cl,nonpenetrating
+Cc1nc(sc1)\[NH]=C(\N)N,penetrating
+c12c(C(N(Cc3n1cnc3c1noc(n1)C(O)(C)C)C)=O)c(ccc2)Cl,nonpenetrating
+C1C(CCN(C1)C(NC1CCCCC1)=S)c1c[nH]cn1,penetrating
+C([C@@](C(O)=O)(NN)C)c1cc(c(O)cc1)O,nonpenetrating
+c1(ccc(O)c(c1)O)CCN,nonpenetrating
+c1(c(ccc(c1)C[C@@H](C(O)=O)N)O)O,penetrating
+c12c(c(cc(n2)C(F)(F)F)[C@@H]([C@H]2CCCCN2)O)cccc1C(F)(F)F,penetrating
+c12c3c(N4CCN(C)CC4)c(F)c(c1c(ccn2[C@H](C)CO3)=O)C(O)=O,penetrating
+c1(ccc2C(=NC[C@@H](N(C)c2c1)CNC(c1ccc(cc1)C)=O)c1ccc(cc1)F)C,penetrating
+C1C(C=C2[C@](C1)([C@@H]1[C@@H](CC2)[C@H]2[C@](C[C@@H]1O)([C@H](CC2)C(CO)=O)C=O)C)=O,nonpenetrating
+C[N@]1CCc2cccc3c2[C@@H]1Cc1ccc(O)c(O)c31,penetrating
+c1ccc2c(c1)n(c(n2)NC1CCN(CC1)CCc1ccc(cc1)OC)Cc1ccc(cc1)F,nonpenetrating
+c1(cc(c(cc1)Cl)Cl)CC(N1CCCC[C@H]1CN1CCCC1)=O,penetrating
+c1(cc(c(cc1)Cl)Cl)CC(N1[C@@H](c2c(CC1)cccc2)CN1CCCC1)=O,penetrating
+c1(ccc(cc1)C(F)(F)F)CC(N1[C@@H](CCCC1)CN1CCCC1)=O,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)scc2)CN1CCCC1)=O,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)[nH]cn2)CN1CCCC1)=O,nonpenetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)ccs2)CN1CCCC1)=O,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](CN2CCCC2)CC(CC1)(C)C)=O,penetrating
+CC(C)(C(O)=O)c1ccc(cc1)C(=O)CCCN1CCC(CC1)OC(c1ccccc1)c1ccccc1,nonpenetrating
+c1c(ccc([C@@H](c2ccccc2)N2CCN(CC2)CCOCC(=O)O)c1)Cl,nonpenetrating
+c1(c(cc2c(c1)n(cc(c2=O)C(O)=O)C1CC1)F)N1CCNCC1,nonpenetrating
+C1C(C=C2[C@](C1)([C@@H]1[C@@H](CC2)[C@H]2[C@](C[C@H]1O)([C@H](CC2)C(CO)=O)C)C)=O,nonpenetrating
+C1C(C=C2[C@](C1)([C@@H]1[C@@H](CC2)[C@H]2[C@](C[C@@H]1O)([C@](CC2)(C(CO)=O)O)C)C)=O,nonpenetrating
+c1cn(CCO)c(CC)c(O)c1=O,nonpenetrating
+c1cn(CCCCO)c(CC)c(O)c1=O,nonpenetrating
+c1cn(c(c(c1=O)O)C)C,penetrating
+c1cn(CC)c(c(c1=O)O)C,penetrating
+c1cn(CCCC)c(C)c(O)c1=O,penetrating
+c1cn(CCCCCC)c(C)c(O)c1=O,penetrating
+c1cn(CCCCC)c(C)c(O)c1=O,penetrating
+c1cn(CCCO)c(C)c(O)c1=O,nonpenetrating
+c1cn(CC)c(CC)c(c1=O)O,penetrating
+C[C@]12c3c(C[C@H]([C@H]1C)[N@](CC2)CC1CC1)ccc(c3)O,penetrating
+CN1CCN(CC1)c1cc2n(cc(C(O)=O)c(=O)c2cc1F)c1ccc(F)cc1,nonpenetrating
+O(C(c1ccccc1)c1ccccc1)CCN(C)C,penetrating
+CN(C)CCO[C@@](C)(c1ccccc1)c1ccccn1,penetrating
+c1ccc([C@H](C[N@]2CC[C@H](C2)O)N(C(Cc2ccccc2N)=O)C)cc1,nonpenetrating
+c1(c(cc2c(n1)n(cc(c2=O)C(O)=O)CC)F)N1CCNCC1,nonpenetrating
+c1cc2c(cc1O)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2O)C,penetrating
+CN1CCN(CC1)c1c(F)cc2c(=O)c(cn(CCF)c2c1F)C(O)=O,nonpenetrating
+OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1,penetrating
+C(=O)(O)c1c(NCc2ccco2)cc(c(c1)S(N)(=O)=O)Cl,nonpenetrating
+c1(cc(c(cc1)Cl)Cl)CC(N1[C@@H](CN2CCCC2)CN(CC1)C(=O)C)=O,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)occ2)CN1CCCC1)=O,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN(CC1)C(=O)OC)CN1CCCC1)=O,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN(CC1)C(=O)OCC)CN1CCCC1)=O,penetrating
+c1(CC(N2[C@H](CN(CC2)C(=O)OCCC)CN2CCCC2)=O)cc(c(cc1)Cl)Cl,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)occ2)C[N@@]1C[C@@H](CC1)O)=O,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(=O)N1[C@H](CN(C(=O)C)CC1)C[N@@]1C[C@H](O)CC1,nonpenetrating
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)ccc(C(F)(F)F)cc1,nonpenetrating
+c1(ccc(cc1)SC)CC(N1[C@H](CN(CC1)C(=O)C)C[N@]1CC[C@H](C1)O)=O,nonpenetrating
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)cc(cc(c1)F)F,nonpenetrating
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)cc(ccc1)OC,nonpenetrating
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)ccc(N(=O)=O)cc1,nonpenetrating
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)ccc(OC)cc1,nonpenetrating
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)cc(ccc1)N(=O)=O,nonpenetrating
+c1(ccccc1)CC(N1[C@H](CN(CC1)C(=O)C)C[N@]1CC[C@H](C1)O)=O,nonpenetrating
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)ccc([S@](=O)C)cc1,nonpenetrating
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)ccc(S(=O)(=O)C)cc1,nonpenetrating
+CC(C)[C@@H](N(C)C(=O)Cc1ccc(c(c1)Cl)Cl)CN1CCCC1,penetrating
+c1(ccccc1)[C@H](CN1CCCC1)N(C(=O)Cc1ccc(c(c1)Cl)Cl)C,penetrating
+CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc1cc(C)on1,nonpenetrating
+c1cc2c(cc1O)[C@]13[C@@H]([C@@H](C2)[N@@](CC=C)CC3)CCCC1,penetrating
+CCn1cc(C(O)=O)c(=O)c2cc(F)c(N3CCN[C@H](C)C3)c(F)c12,nonpenetrating
+CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1,nonpenetrating
+C1Cc2c(\C(c3c1cc(cc3)Cl)=C1/CCN(CC1)C(=O)OCC)nccc2,nonpenetrating
+CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc1ncc(C)s1,nonpenetrating
+c12[C@@]34[C@H]5[C@@H]([N@](CC=C)CC4)Cc2ccc(c1O[C@@H]3[C@@H](O)C=C5)O,penetrating
+c12[C@@]34[C@]5([C@@H]([N@](CC6CC6)CC4)Cc2ccc(c1O[C@@H]3C(=O)CC5)O)O,penetrating
+c1(c(cc2c(c1)n(cc(c2=O)C(O)=O)CC)F)N1CCNCC1,nonpenetrating
+CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCN(C)CC1,nonpenetrating
+c12c(Sc3c(N1CCCN1CCN(CC1)CCO)cc(cc3)Cl)cccc2,penetrating
+c1ccc2c(c1)C(=C(N(S2(=O)=O)C)C(Nc1ncccc1)=O)O,nonpenetrating
+C1[C@H]2[C@H]([C@H]3[C@]([C@@H](C(C)=O)CC3)(C)C1)CCC=1[C@@]2(CCC(C1)=O)C,penetrating
+Oc1ccc2[nH]cc(CCCC[N@@]3CCC(=CC3)c3ccccc3)c2c1,penetrating
+c1ccc2N([C@H](CN3CCCC3)C)c3c(ccc(C(=O)NCCC)c3)Sc2c1,penetrating
+CN1CCN(CC1)c1c(F)cc2c(=O)c(cn3CCSc1c23)C(O)=O,nonpenetrating
+CC(C)(C)NC[C@@H](O)c1ccc(O)c(CO)c1,nonpenetrating
+c1(ccc(c(c1)Cl)Cl)CC(=O)N1[C@H](C[N@@](C)CC1)CN1CCCC1,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN2CCCC2)c2n(CC1)ccn2)=O,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](C[C@]2(CC1)NC(NC2=O)=O)CN1CCCC1)=O,nonpenetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](C[C@]2(CC1)C(NC(N2)=O)=O)CN1CCCC1)=O,nonpenetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](C[N@@]2C[C@@H](CC2)O)c2n(CC1)ccn2)=O,nonpenetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN2CCCC2)c2n(CC1)ncn2)=O,penetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](C[N@@]2C[C@@H](CC2)O)C[N@](CC1)CCO)=O,nonpenetrating
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](C[N@@]2C[C@@H](CC2)O)c2c(CC1)[nH]cn2)=O,nonpenetrating
+c1ccc2nc(c(c(C(N[C@@H](CC)c3ccccc3)=O)c2c1)O)c1ccccc1,penetrating
+c1cc2c(C(N[C@@H](CC)c3ccccc3)=O)c(c(nc2cc1)c1ccccc1)OCCCN(C)C,penetrating
+c1cc2c(C(N[C@@H](CC)c3ccccc3)=O)c(c(nc2cc1)c1ccccc1)OCC(O)=O,nonpenetrating
+c1cc2c(C(N[C@@H](CC)c3ccccc3)=O)c(c(c3ccccc3)nc2cc1)OCCCC(O)=O,nonpenetrating
+c1ccc2c(c(C(N[C@@H](CC)c3ccccc3)=O)c(OCCNC(Cc3c(cccc3)C(=O)O)=O)c(c3ccccc3)n2)c1,nonpenetrating
+c1cc2c(c(OCCNC(Cc3ncccc3)=O)c(c3ccccc3)nc2cc1)C(N[C@@H](CC)c1ccccc1)=O,nonpenetrating
+c1cc2c(c(c(c3ccccc3)nc2cc1)OCCNC([C@@H]1CCCN1)=O)C(=O)N[C@@H](CC)c1ccccc1,nonpenetrating
+c1cc2c(C(N[C@@H](CC)c3ccccc3)=O)c(c(nc2cc1)c1ccccc1)Cn1cncc1,nonpenetrating
+c1(c(c(c2c(c1F)n(cc(c2=O)C(O)=O)C1CC1)N)F)N1C[C@@H](N[C@@H](C1)C)C,nonpenetrating
+CCNCc1c(CSC)cnc(C)c1O,penetrating
+CN1C(=C(O)c2sccc2S1(=O)=O)C(=O)Nc1ccccn1,nonpenetrating
+CC(C)(C)c1ccc(cc1)[C@H](O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1,nonpenetrating
+C1C(C=C2[C@](C1)([C@@H]1[C@@H](CC2)[C@H]2[C@](CC1)([C@H](CC2)O)C)C)=O,penetrating
+C1CC[C@H]([C@@H](N(C(Cc2ccc(c(c2)Cl)Cl)=O)C)C1)N1CCCC1,penetrating
diff --git a/classification/blood-brain-barrier.json b/classification/blood-brain-barrier.json
new file mode 100644
index 0000000..b271ec1
--- /dev/null
+++ b/classification/blood-brain-barrier.json
@@ -0,0 +1,5 @@
+{
+ "species": "Human",
+ "endpoint": "Blood Brain Barrier Penetration",
+ "source": "http://cheminformatics.org/datasets/"
+}
diff --git a/classification/hamster_carcinogenicity.csv b/classification/hamster_carcinogenicity.csv
new file mode 100644
index 0000000..52d89a3
--- /dev/null
+++ b/classification/hamster_carcinogenicity.csv
@@ -0,0 +1,86 @@
+SMILES, Hamster Carcinogenicity
+CC=O,true
+C12C3=C(C=CC=C3)CC1=CC(=CC=2)NC(C)=O,true
+O=C(N)\C(C2=CC=CO2)=C/C1=CC=C([N+]([O-])=O)O1,true
+C1(N=CNN=1)N,false
+Br(=O)(=O)[O-].[K+],true
+[Cl-].[Cd+2].[Cl-],false
+O=S(=O)([O-])[O-].[Cd+2],false
+ClC1=CC(=NC(=N1)SCC(=O)O)NC2=CC=CC(=C2C)C,false
+ClCOC,true
+C=C(Cl)C=C,false
+Clc1ccc(cc1)c2ccc(COC(C)(C)C(O)=O)cc2,false
+O=C1OC2=C(C=CC=C2)C=C1,false
+ClC(=C(C1=CC=C(C=C1)Cl)C2=CC=C(C=C2)Cl)Cl,true
+ClC(C(C1=CC=C(C=C1)Cl)C2=CC=C(C=C2)Cl)(Cl)Cl,false
+C=CCN(CC=C)N=O,true
+Cl\C2=C(/Cl)C3(Cl)C1C4CC(C1C2(Cl)C3(Cl)Cl)C5OC45,false
+O=C(N(C)C)Cl,true
+CN(C)N,true
+N(NC)C.[H]Cl.[H]Cl,true
+CCO,false
+O=C(N(CC)N=O)NCCO,true
+O=C(N(CC)N=O)NCC(=O)C,true
+C=O,false
+[O-][N+](=O)C1=CC=C(O1)C2=CSC(=N2)NNC=O,true
+O=CC1=CC=CO1,false
+OCC1CO1,true
+O=C2C1=C(OC)C=C(OC)C(Cl)=C1O[C@]32C(OC)=CC(C[C@@](C)3[H])=O,false
+ClC1=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl,true
+NN,true
+OS(=O)(=O)O.NN,true
+CC(=O)N(O)C1=CC2=C(C=C1)C3=CC=CC=C3C2,true
+OCCNN,false
+O=C(C1=CC=NC=C1)NN,false
+OC(=O)C1=CC=NC=C1,false
+O=C(NC1=CC=CC(=C1)Cl)OC(C)C,false
+O=C(NC1=CC=CC=C1)OC(C)C,false
+[O-]C(C)=O.[O-]C(C)=O.[Pb+2].[OH-].[OH-].[Pb+2].[OH-].[OH-].[Pb+2],false
+CN(C)CCN(CC2=CC=CS2)C1=NC=CC=C1.Cl,false
+NC1=C2C(=NC(=N1)N)N=CC(=N2)CN(C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C,false
+CN(N)C=O,true
+O=C(C(=C)C)OC,false
+CNN,true
+O=C(C1=CC=CN=C1)CCCN(N=O)C,false
+CC1=CC(=O)NC(=S)N1,true
+CC(C(O)=O)(OC1=CC=C(C=C1)C2CCCC3=C2C=CC=C3)C,false
+O=N[O-].[Na+],false
+[O-][N+](C1=CC=C(C2=CSC(NC(C)=O)=N2)O1)=O,true
+[O-][N+](=O)C1=CC=C(O1)C2=CSC(=N2)NC=O,true
+O=[N+](C1=CC=C2C3=C1C=CC=C3CC2)[O-],false
+N(CC(CO)O)(CC(O)C)N=O,true
+N(CC(CO)O)(CC(C)=O)N=O,true
+N(CC(CO)O)(CCO)N=O,false
+O=C(C)CN(N=O)CCO,true
+C1C(N(C(CN1N=O)C)C)C,true
+N(CC(C)=O)(CC=C)N=O,true
+N(CC(CO)O)(C)N=O,true
+O=NN1CCOCC1,true
+N1C=CC=C(C=1)C2N(N=O)CCC2,true
+C1=CC=C(C=[N+]1[O-])C2CCCN2N=O,false
+O=NN1CCCCC1,true
+O=NN1CCCC1,true
+O=C(N(CC(C)=O)N=O)NCCCl,true
+N(C(=O)N)(N=O)CC(C)=O,true
+C1(CCN=C=S)=CC=CC=C1,false
+O=C1C(C2=CC=CC=C2)(C(=O)NC(=O)N1)CC,false
+C1=C2C(=CC=C1NC3=CC=CC=C3)C=CC=C2,false
+O=C1N2C(C3=C(C=CC=C3)CC2)CN(C1)C(=O)C4CCCCC4,false
+C1(=CC(=C(O)C=C1)O)C(O)=O,false
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diff --git a/classification/hamster_carcinogenicity.json b/classification/hamster_carcinogenicity.json
new file mode 100644
index 0000000..8c17d9d
--- /dev/null
+++ b/classification/hamster_carcinogenicity.json
@@ -0,0 +1,3 @@
+{ "species": "Hamster",
+"endpoint": "Carcinogenicity",
+"source": "http://www.epa.gov/ncct/dsstox/sdf_cpdbas.html" }
diff --git a/classification/kazius.csv b/classification/kazius.csv
new file mode 100644
index 0000000..3297a15
--- /dev/null
+++ b/classification/kazius.csv
@@ -0,0 +1,4070 @@
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diff --git a/classification/kazius.json b/classification/kazius.json
new file mode 100644
index 0000000..4f4304e
--- /dev/null
+++ b/classification/kazius.json
@@ -0,0 +1,5 @@
+{
+ "species": "Salmonella typhimurium",
+ "endpoint": "Mutagenicity",
+ "source": "http://cheminformatics.org/datasets/"
+}
diff --git a/create_prediction_models.rb b/create_prediction_models.rb
new file mode 100644
index 0000000..0ec5e25
--- /dev/null
+++ b/create_prediction_models.rb
@@ -0,0 +1,66 @@
+ENV["LAZAR_ENV"] = "development"
+require_relative '../lazar/lib/lazar'
+#require 'lazar'
+include OpenTox
+#$mongo.database.drop
+#$gridfs = $mongo.database.fs # recreate GridFS indexes
+
+=begin
+# classification models
+Dir["classification/*csv"].each do |file|
+ unless file.match(/hamster/)
+ Model::Prediction.from_csv_file file
+ end
+end
+
+# regression models
+Dir["regression/*log10.csv"].each do |file|
+ Model::Prediction.from_csv_file file
+end
+=end
+
+## nano-lazar
+=begin
+
+# creates 3 models: one with physchem, one with proteomics, one with fingerprints
+feature_categories = ["fingerprint", "P-CHEM", "Proteomics"]
+
+feature_categories.each do |category|
+ if category == "fingerprint"
+ algorithms = {
+ :descriptors => { :method => "fingerprint", :type => "MP2D", },
+ :feature_selection => nil,
+ :similarity => {
+ :method => "Algorithm::Similarity.tanimoto",
+ :min => 0.1
+ }
+ }
+
+ OpenTox::Model::Validation.from_enanomapper algorithms: algorithms
+ else
+ algorithms = {
+ :descriptors => {
+ :method => "properties",
+ :categories => (category.is_a?(Array) ? [category].flatten : [category]),
+ },
+ :similarity => {
+ :method => "Algorithm::Similarity.weighted_cosine",
+ :min => 0.5
+ },
+ :prediction => {
+ :method => "Algorithm::Caret.rf",
+ },
+ :feature_selection => {
+ :method => "Algorithm::FeatureSelection.correlation_filter",
+ },
+ }
+
+ OpenTox::Model::Validation.from_enanomapper algorithms: algorithms
+ end
+end
+=end
+
+# save
+
+#`mongodump -h 127.0.0.1 -d development`
+#`mongorestore --host 127.0.0.1`
diff --git a/regression/EPAFHM.csv b/regression/EPAFHM.csv
new file mode 100644
index 0000000..9092abc
--- /dev/null
+++ b/regression/EPAFHM.csv
@@ -0,0 +1,618 @@
+"STRUCTURE_SMILES","LC50_mmol"
+"C1=CC(C=O)=CC(OC)=C1OCCCCCC",1.13E-02
+"C1(OC)=C([N+]([O-])=O)C(C=O)=CC(Br)=C1O",2.66E-01
+"CCCCCCCCOC(=O)C1=CC=CC(C(=O)OCCCCCCCC)=C1",
+"C1=CC(Cl)=CC=C1OC2=C([N+](=O)[O-])C=CC=C2",7.69E-03
+"CC1=C(NC=O)C=CC=C1Cl",2.75E-01
+"CCCCOC(=O)C1=CC=CC(C(=O)OCCCC)=C1",3.23E-03
+"C(C1=CC=CC=C1)(C2=CC=CC=C2)(O)C#C",5.33E-02
+"CCCSCCSCCC",4.22E-02
+"CCCCCCCCOC(=O)C1=CC=C(C(=O)OCCCCCCCC)C=C1",
+"OCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCOC(=O)C2=CC=CC=C2C(=O)OCCCCO",
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diff --git a/regression/EPAFHM.json b/regression/EPAFHM.json
new file mode 100644
index 0000000..9090f0f
--- /dev/null
+++ b/regression/EPAFHM.json
@@ -0,0 +1,5 @@
+{ "species": "Fathead minnow",
+ "endpoint": "Acute toxicity",
+ "source": "http://www.epa.gov/comptox/dsstox/sdf_epafhm.html",
+ "unit": "mmol"
+}
diff --git a/regression/EPAFHM_log10.csv b/regression/EPAFHM_log10.csv
new file mode 100644
index 0000000..9294f24
--- /dev/null
+++ b/regression/EPAFHM_log10.csv
@@ -0,0 +1,581 @@
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diff --git a/regression/EPAFHM_log10.json b/regression/EPAFHM_log10.json
new file mode 100644
index 0000000..9090f0f
--- /dev/null
+++ b/regression/EPAFHM_log10.json
@@ -0,0 +1,5 @@
+{ "species": "Fathead minnow",
+ "endpoint": "Acute toxicity",
+ "source": "http://www.epa.gov/comptox/dsstox/sdf_epafhm.html",
+ "unit": "mmol"
+}
diff --git a/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol.csv b/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol.csv
new file mode 100644
index 0000000..7bfe9e8
--- /dev/null
+++ b/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol.csv
@@ -0,0 +1,1217 @@
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diff --git a/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol.json b/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol.json
new file mode 100644
index 0000000..accbe49
--- /dev/null
+++ b/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol.json
@@ -0,0 +1,5 @@
+{ "species": "Human",
+ "endpoint": "Maximum Recommended Daily Dose",
+ "source": "http://www.epa.gov/comptox/dsstox/sdf_fdamdd.html",
+ "unit": "mmol/kg-bw/day"
+}
diff --git a/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol_log10.csv b/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol_log10.csv
new file mode 100644
index 0000000..198f680
--- /dev/null
+++ b/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol_log10.csv
@@ -0,0 +1,1217 @@
+STRUCTURE_SMILES,-log10(Dose_MRDD_mmol)
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diff --git a/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol_log10.json b/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol_log10.json
new file mode 100644
index 0000000..accbe49
--- /dev/null
+++ b/regression/FDA_v3b_Maximum_Recommended_Daily_Dose_mmol_log10.json
@@ -0,0 +1,5 @@
+{ "species": "Human",
+ "endpoint": "Maximum Recommended Daily Dose",
+ "source": "http://www.epa.gov/comptox/dsstox/sdf_fdamdd.html",
+ "unit": "mmol/kg-bw/day"
+}
diff --git a/regression/daphnia_magna.csv b/regression/daphnia_magna.csv
new file mode 100644
index 0000000..c5a4866
--- /dev/null
+++ b/regression/daphnia_magna.csv
@@ -0,0 +1,547 @@
+SMILES,LC50[mol/L]
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+Brc1ccc(c(c1)Br)Oc1cc(Br)c(cc1Br)Br,9.571940712948441e-08
+Brc1ccc(c(c1)Br)Oc1ccc(cc1Br)Br,1.892343618644976e-07
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+O=C1CCCN1C,1.241652307592412e-05
+O=C1CN=C(c2c(N1)ccc(c2)[N+](=O)[O-])c1ccccc1Cl,9.50604793656281e-05
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+Oc1cc(Cl)c(c(c1)Cl)Cl,3.459393778261217e-06
+S=C(Nc1ccccc1)Nc1ccccc1,0.00029444216337987605
+S=C1SSC2=NCCN12,1.1967405313072443e-06
+[O-][N+](=O)c1ccccc1Cl,0.00022908676527677723
+c1cc2ccc3c4c2c(c1)ccc4ccc3,6.714288529259523e-07
+c1ccc(cc1)NNc1ccccc1,2.2335722228305327e-05
+c1ccc2c(c1)Oc1c(C2)cccc1,0.00011142945335917303
+c1ccc2c(c1)cc1c(c2)ccc2c1cccc2,6.039486293763794e-07
+c1ccc2c(c1)oc1c2cccc1,1.0115794542598983e-05
+c1ccccc1,0.003311311214825911
diff --git a/regression/daphnia_magna.json b/regression/daphnia_magna.json
new file mode 100644
index 0000000..ff1a7bf
--- /dev/null
+++ b/regression/daphnia_magna.json
@@ -0,0 +1,4 @@
+{ "species": "Daphnia magna",
+ "endpoint": "Acute toxicity",
+ "source": "http://michem.disat.unimib.it/chm/download/toxicity.htm"
+}
diff --git a/regression/daphnia_magna_log10.csv b/regression/daphnia_magna_log10.csv
new file mode 100644
index 0000000..89d223a
--- /dev/null
+++ b/regression/daphnia_magna_log10.csv
@@ -0,0 +1,547 @@
+SMILES,-log10(LC50[mol/L])
+BrC(Br)Br,3.740
+BrC=C(Br)Br,4.330
+Brc1ccc(c(c1)Br)Oc1cc(Br)c(cc1Br)Br,7.019
+Brc1ccc(c(c1)Br)Oc1ccc(cc1Br)Br,6.723
+Brc1ccc(cc1)Oc1ccccc1,5.979
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+C=Cc1ccccc1,3.533
+CBr,4.632
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diff --git a/regression/daphnia_magna_log10.json b/regression/daphnia_magna_log10.json
new file mode 100644
index 0000000..ff1a7bf
--- /dev/null
+++ b/regression/daphnia_magna_log10.json
@@ -0,0 +1,4 @@
+{ "species": "Daphnia magna",
+ "endpoint": "Acute toxicity",
+ "source": "http://michem.disat.unimib.it/chm/download/toxicity.htm"
+}
diff --git a/regression/fathead_minnow.csv b/regression/fathead_minnow.csv
new file mode 100644
index 0000000..6c1b422
--- /dev/null
+++ b/regression/fathead_minnow.csv
@@ -0,0 +1,909 @@
+SMILES,LC50[mol/L]
+ClCCOC(=O)NC1CCCCC1,0.00016982436524617443
+Nc1ccc(cc1)N(=O)=O,0.0007673614893618186
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+O=Cc1ccccc1,0.00012050359403717974
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diff --git a/regression/fathead_minnow.json b/regression/fathead_minnow.json
new file mode 100644
index 0000000..342dd96
--- /dev/null
+++ b/regression/fathead_minnow.json
@@ -0,0 +1,4 @@
+{ "species": "Fathead minnow",
+ "endpoint": "Acute toxicity",
+ "source": "http://michem.disat.unimib.it/chm/download/toxicityfish.htm"
+}
diff --git a/regression/fathead_minnow_log10.csv b/regression/fathead_minnow_log10.csv
new file mode 100644
index 0000000..3a03819
--- /dev/null
+++ b/regression/fathead_minnow_log10.csv
@@ -0,0 +1,909 @@
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+O=C(C(=C)C)OCc1ccccc1,4.577
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+O=N(=O)N1CN(CN(CN(C1)N(=O)=O)N(=O)=O)N(=O)=O,4.295
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+CCSCCCCSCC,4.469
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+O=Cc1ccccc1N(=O)=O,4.021
+CCCCCCCC[N+](CCCCCCCC)(C)C,4.770
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+O=Cc1ccc(cc1)N(=O)=O,4.175
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+C=CCN=C=S,6.064
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+Oc1ccc(c(c1)C(F)(F)F)[N+](=O)[O-],4.399
+N#Cc1c(C)cccc1Cl,4.002
+CCCCCC=O,3.757
+Oc1cccnc1Br,2.569
+CC(Oc1cccc(c1)NC(=O)c1ccccc1C(F)(F)F)C,4.828
+Oc1cccnc1Cl,2.319
+CCOC(=O)C(Oc1ccc(cc1)Oc1nc2c(o1)cc(cc2)Cl)C,4.706
+O=Cc1ccc(cc1)Oc1ccccc1,4.632
+CC(O)C,0.778
+CC(=O)C,0.855
+CS(=O)C,0.361
+ClC(C(Cl)(Cl)Cl)(Cl)Cl,5.242
+OC(=O)CS,3.487
+O=CN(C)C,0.841
+ClC(C(=O)N)Cl,2.725
+N#CC(c1ccc(c(c1)Oc1ccccc1)F)OC(=O)C1C(C1(C)C)C=C(Cl)Cl,8.604
+CCN(C(=O)C)CC,1.885
+C#CCN(CC#C)CC#C,2.647
+CCCCCCC(N)C,4.396
+O=N(=O)OCCOCCON(=O)=O,2.601
+CCCCCCCCC(=O)C,4.510
+CCCCCOCCCCC,4.703
+Cc1cocn1,1.777
+Cc1ncc[nH]1,2.458
+CCOC(CN(CC(OCC)OCC)C)OCC,2.618
+[O-]S(=O)(=O)c1ccc[n+](c1)Cc1ccccc1,2.015
+O=Cc1cccc(c1)Oc1ccc(cc1)C(C)(C)C,5.842
+Clc1cc(Cl)c(c(c1O)Cc1c(O)c(Cl)cc(c1Cl)Cl)Cl,7.287
+CC(=CC1C(C1(C)C)C(=O)OCc1ccc(cc1C)C)C,6.665
+CCC(=O)c1ccc(cc1)N,3.009
+Cc1ccc(c(c1)O)N(=O)=O,3.513
+O=C1C2CC3CC1CC(C2)C3,3.393
+N#CC(c1cccc(c1)Oc1ccccc1)OC(=O)C(c1ccc(cc1)OC(F)F)C(C)C,9.354
+O=N(=O)c1ccc(c(c1N)N(=O)=O)C,4.208
+CCCCCCC1CCC(=O)O1,3.976
+COc1cc(OC)cc(c1C=O)O,4.832
+CCC(=O)Nc1ccc(c(c1)Cl)Cl,4.404
+CCCO,1.121
+CCCCO,1.589
+CCCCCO,2.217
+c1ccccc1,3.502
+CC(Cl)(Cl)Cl,3.402
+CCCC(C1(CC)C(=O)NC(=NC1=O)S)C,4.004
+CCCCCCCCCC[N+](CCCCCCCCCC)(C)C,6.040
+Cc1c(NC=O)cccc1Cl,3.561
+COc1ccc(cc1)C(C(Cl)(Cl)Cl)c1ccc(cc1)OC,7.607
+ClC(C(c1ccc(cc1)Cl)c1ccc(cc1)Cl)Cl,4.862
+NCCCN1CCN(CC1)CCCN,1.810
+C=CC(CCC=C(CCC=C(C)C)C)(O)C,5.192
+ClCCN1CCCC1,3.046
+CCCCCCCCCCCN,5.912
+COP(=S)(SCN1C(=O)c2c(C1=O)cccc2)OC,4.593
+Oc1c(cc(cc1C(C)(C)C)C(C)(C)C)C(C)(C)C,6.634
+CCCCC(C#C)O,4.804
+CCN,2.300
+CC#N,1.399
+CC=O,3.076
+O1CC1,2.720
+ClC(=C)Cl,2.856
+CC(=O)Cl,3.272
+C[N+](C)(C)C,2.375
+CC(O)(C)C,1.063
+OCC(F)(F)F,2.925
+CC(=O)C(C)(C)C,3.061
+OC(=O)C(Cl)(Cl)C,2.693
+COP(=S)(OC)S,3.828
+ClC(C(Cl)(Cl)Cl)Cl,4.440
+OC(=O)C(Cl)(Cl)Cl,1.911
+ClC1C=CC2C1C1(Cl)C(=C(C2(C1(Cl)Cl)Cl)Cl)Cl,7.017
+ClC(C=C)CCl,4.184
+CCCCN(C=O)CCCC,3.246
+CC#CCO,3.841
+CC(=CC=C(C)C)C,4.465
+NC12CC3CC(C2)CC(C1)C3,3.782
+N#Cc1c(C)cc(nc1O)C,2.975
+ClC1=C(Cl)C(C(=C1Cl)Cl)(Cl)Cl,7.591
+O=C1NC(=O)C(N1)(C)C,0.890
+C1=CC2C(C1)C1C=CC2C1,3.407
+CCC(CC)(O)C,2.182
+CC(C#C)(CC)O,1.906
+COP(=O)(OC(=CC(=O)OC(c1ccccc1)C)C)OC,4.422
+Fc1c(N)c(F)c(c(c1F)F)F,3.693
+CC1=CCC2CC1C2(C)C,5.689
+C#CC1(O)CCCCC1,2.686
+CCOP(=S)(SC1OCCOC1SP(=S)(OCC)OCC)OCC,4.691
+CCCCOCCOP(=O)(OCCOCCCC)OCCOCCCC,4.551
+CC1=CC(=O)CC(C1)(C)C,2.737
+C=CC(=C)C,2.953
+OCC(C)C,1.691
+ClCC(Cl)C,2.928
+NCC(N)C,1.817
+CCC(O)C,1.305
+CCC(=O)C,1.352
+CC(CN)O,1.474
+CCOP(=S)(OCC)SCSc1ccc(cc1)Cl,6.160
+ClCC(Cl)Cl,3.213
+ClC=C(Cl)Cl,3.470
+NC(=O)C=C,2.766
+COC(=O)C,2.269
+ClC(C(Cl)Cl)Cl,3.916
+CC(=O)C=CC1=C(C)CCCC1(C)C,4.577
+CC(c1cc(Cl)c(c(c1)Cl)O)(c1cc(Cl)c(c(c1)Cl)O)C,5.440
+O=P(c1ccccc1)(c1ccccc1)c1ccccc1,3.715
+O=Cc1cccc(c1)Oc1ccc(c(c1)Cl)Cl,5.950
+CC(c1ccc(cc1)O)(c1ccc(cc1)O)C,4.691
+CC(c1ccc(cc1)Cl)(c1ccc(cc1)Cl)O,5.264
+CCC(c1ccc(cc1)O)(C)C,4.810
+CC1(N)CCC(CC1)C(N)(C)C,3.416
+O=CC(Cc1ccc(cc1)C(C)(C)C)C,4.611
+COC(=O)C(=C)C,2.495
+CN=C1C=CC(C=C1)C(c1ccc(cc1)N(C)C)c1ccc(cc1)N(C)C,6.923
+ClC(c1c(Cl)cccc1Cl)Cl,5.372
+COP(=O)(OC)O,3.845
+OCCOC(=O)C=C,4.384
+CCCCCC(C#C)O,5.485
+CCCCCCCC(=O)C,3.971
+ClC1CCCCC1Cl,3.920
+c1cc2cccc3c2c(c1)CC3,4.984
+Cc1c[nH]c2c1cccc2,4.171
+COc1cc2c(cc1OC)OCC1C2C(=O)c2c(O1)c1CC(Oc1cc2)C(=C)C,7.849
+Oc1ccc(cc1)Oc1ccccc1,4.578
+CCNc1nc(NC(C)C)nc(n1)SC,4.377
+O=C(c1ccccc1C(=O)Oc1ccccc1)Oc1ccccc1,6.600
+CCOC(=O)c1ccccc1C(=O)OCC,4.116
+CC(COC(=O)c1ccccc1C(=O)OCC(C)C)C,5.490
+CCCCOC(=O)c1ccccc1C(=O)OCCCC,5.367
+O=CC=C1N(C)c2c(C1(C)C)cccc2,4.711
+CCCCOC(=O)c1ccccc1C(=O)OCc1ccccc1,5.224
+O=N(=O)c1cccc2c1cccc2,4.284
+c1ccc2c(c1)[nH]c1c2cccc1,5.292
+CC(=C)C(=O)OCCO,2.758
+COP(=O)OC,2.689
+O=C(c1ccccc1O)Nc1ccccc1,4.732
+Clc1c(Cl)cccc1Cl,4.890
+ClC(=C(Cl)Cl)C(=C(Cl)Cl)Cl,6.416
+OC1COC(C(C1O)O)O,0.600
+CCOC(=O)C(C(C(=O)OCC)O)O,2.501
+Brc1cscc1,4.421
+O=Cc1ccc(cc1Cl)Cl,4.988
+Clc1cc(Cl)c(c(c1)Cl)O,4.499
+NC(=O)c1ccccc1N,2.537
+O=N(=O)c1ccccc1C,3.568
+O=N(=O)c1ccccc1Cl,3.731
+O=N(=O)c1ccccc1O,2.939
+CCC(c1cc(cc(c1O)N(=O)=O)N(=O)=O)C,6.236
+c1ccc(cc1)SSc1ccccc1,6.298
+CCOC(=O)c1cccc(c1)N,3.522
+Clc1ccc(c(c1Cl)N)Cl,4.730
+Cc1ccc(c(c1)N(=O)=O)N,3.789
+Cc1ccc(c(c1)O)C(C)C,4.672
+O=Cc1ccccc1Cl,4.750
+O=Cc1ccccc1O,4.725
+Cc1cccc2c1cccc2,4.199
+Clc1cccc2c1cccc2,4.849
+Oc1cccc2c1cccc2,4.538
+Oc1ccccc1c1ccccc1,4.507
+O=Cc1cc(Br)cc(c1O)Br,5.518
+OCCOc1ccc(cc1)C(CC(C)(C)C)(C)C,4.668
+c1ccc2c(c1)cccc2,4.322
+c1ccc2c(c1)nccc2,3.448
+COc1ccccc1N(=O)=O,2.904
+CCN(C1CCCCC1)CC,3.861
+CCN(c1ccccc1)CC,3.959
+OCCN(c1cccc(c1)C)CC,3.530
+Nc1ccc(cc1Cl)c1ccc(c(c1)Cl)N,5.107
+c1ccc(cc1)c1ccccc1,4.809
+Oc1ccc(cc1)c1ccccc1,4.440
+OC(C(F)(F)F)C(F)(F)F,2.838
+C=CCC(C=C)O,3.411
+OCCC#C,3.288
+CCOC(=O)c1ccccc1,4.247
+O=C(c1ccccc1)CC(=O)C,5.169
+CC(=O)c1cccn1C,2.895
+Clc1cc(Cl)c(c(c1Cl)O)Cl,5.348
+ClCC(=O)c1ccc(cc1)Cl,4.208
+c1ccc(cc1)c1ccncc1,3.984
+CCOC(=O)c1ccc(cc1)N,3.665
+O=C(N1CCCCC1)C=CC=Cc1ccc2c(c1)OCO2,4.561
+ON=Cc1ccccc1O,4.628
+OC(=O)COc1ccc(cc1Cl)Cl,2.839
+OC(=O)CCCOc1ccc(cc1C)Cl,4.262
+OC(=O)CCCOc1ccc(cc1Cl)Cl,4.141
+CCP(=S)(Sc1ccccc1)OCC,5.354
+O=S(c1ccccc1)c1ccccc1,3.365
+O=Cc1ccc(cc1O)O,4.023
+c1ccc2c(c1)scn2,3.325
+Cc1ccccc1C,3.811
+Cc1ccccc1O,3.897
+Cc1ccccc1Cl,4.230
+Clc1ccccc1Cl,4.194
+Nc1ccccc1Cl,4.353
+Cc1ccccc1F,3.753
+Cc1ccccc1N,3.120
+Oc1ccccc1Cl,3.995
+Cc1ccc(c(c1)C)C,4.192
+Oc1ccc(c(c1)C)C,3.920
+Clc1ccc(c(c1)Cl)C,4.540
+Cc1ccc(c(c1)Cl)Cl,4.743
+Nc1ccc(c(c1)Cl)Cl,4.332
+Nc1ccc(c(c1)N)C,1.935
+Clc1ccc(c(c1)N)Cl,4.989
+Clc1cc(Cl)c(cc1Cl)Cl,5.815
+Clc1cc(Cl)c(cc1O)Cl,5.192
+c1ccc(cc1)c1ccc(o1)c1ccccc1,6.644
+CN(C(=O)C(c1ccccc1)c1ccccc1)C,3.698
+C=CCOC(=O)C(=C)C,5.105
+O1CC1c1ccccc1,4.050
+OCC(CBr)Br,3.487
+CC(C=O)CC,3.937
+ClCC(CCl)Cl,3.408
+CCC(=O)CC,1.748
+CC(=NO)CC,2.014
+OCCN(C(C)C)C(C)C,2.859
+O=N(=O)c1ccc(c(c1)N(=O)=O)N,4.084
+Oc1ccc(cc1Cc1cc(Cl)ccc1O)Cl,5.939
+C=CCc1ccc(c(c1)OC)O,3.835
+O=Cc1ccco1,3.660
+O=Cc1cccs1,3.460
+Nc1cccc(c1)C(F)(F)F,3.769
+CC(c1ccc(cc1)O)(C)C,4.463
+CC(c1ccccc1)C,4.279
+CC(=O)c1ccccc1,2.870
+ClC(=O)c1ccccc1,3.615
+O=N(=O)c1ccccc1,3.022
+COc1c(N(=O)=O)c(C=O)cc(c1O)Br,3.575
+Nc1cccc(c1)C(=O)C,2.550
+Cc1cccc(c1)N(=O)=O,3.660
+O=N(=O)c1cc(cc(c1)N(=O)=O)N(=O)=O,5.303
+O=N(=O)c1ccc(c(c1)C)N,3.242
+O=N(=O)c1ccc(c(c1)N)C,3.345
+O=Cc1cccc(c1)N(=O)=O,4.416
+O=N(=O)c1cccc(c1)N(=O)=O,4.239
+CC1=CC=C(CC1)C(C)C,4.638
+Cc1ccc(cc1)N(C)C,3.415
+Cc1ccc(cc1)N(=O)=O,3.441
+CC(COC(=O)C=C)O,4.590
+CC(=O)O,2.661
+CCOC(=O)C=CC(=O)OCC,4.282
+CC1CCC(C(C1)O)C(C)C,3.919
+OC(=O)c1nc(Cl)c(c(c1Cl)N)Cl,3.350
+CCOC(=O)C(N(C(=O)c1ccccc1)c1ccc(c(c1)Cl)Cl)C,5.749
+N#CC(c1cccc(c1)Oc1ccccc1)OC(=O)C(c1ccc(cc1)Cl)C(C)C,8.916
+CC(C(Cl)(Cl)Cl)(O)C,3.130
+C=CCC1=C(C)C(CC1=O)OC(=O)C1C(C1(C)C)C=C(C)C,6.683
+ClC1=C(Cl)C2(C(C1(Cl)C1C2C2CC1C1C2O1)(Cl)Cl)Cl,8.433
+BrC1C(=O)C2(C(C1CC2)(C)C)C,3.529
+Clc1c(O)c(Cl)c(c(c1Cl)Cl)Cl,6.093
+OCCC=CCC,2.494
+C[N+](c1ccccc1)(C)C,3.017
+c12c(cc(Cl)cc1)OC(=O)N2CSP(=S)(OCC)OCC,6.238
+C1(=O)C=CSN1CCCCCCCC,6.183
+C1(=O)C(Br)=C(C)NC(=O)N1C(C)CC,3.152
+C12C(=O)c3c(C(=O)C=1SC(C#N)=C(C#N)S2)cccc3,6.254
+C1(=O)N(C2CCCCC2)C(=O)N(C)C(N(C)C)=N1,2.964
+C1(=O)c2c(cccc2)OC(c2ccccc2)=C1,4.803
+CN1c2ncn(C)c2C(=O)N(C)C1=O,3.109
+c1(C2C(=O)C(c3cc(C(F)(F)F)ccc3)=CN(C)C=2)ccccc1,4.040
+C1(O)c2c(cccc2)OC(=O)C=1CC1C(=O)Oc2c(C=1O)cccc2,4.818
+C1(=O)c2c(cccc2)N=NN1CSP(=S)(OC)OC,5.317
+C1(=O)C(Cl)=C(SCc2ccc(C(C)(C)C)cc2)C=NN1C(C)(C)C,8.201
diff --git a/regression/fathead_minnow_log10.json b/regression/fathead_minnow_log10.json
new file mode 100644
index 0000000..342dd96
--- /dev/null
+++ b/regression/fathead_minnow_log10.json
@@ -0,0 +1,4 @@
+{ "species": "Fathead minnow",
+ "endpoint": "Acute toxicity",
+ "source": "http://michem.disat.unimib.it/chm/download/toxicityfish.htm"
+}
diff --git a/scripts/bbp2blood-brain-barrier.rb b/scripts/bbp2blood-brain-barrier.rb
new file mode 100644
index 0000000..aab8872
--- /dev/null
+++ b/scripts/bbp2blood-brain-barrier.rb
@@ -0,0 +1,18 @@
+require_relative '../../lazar/lib/lazar'
+include OpenTox
+
+CSV.open("../classification/blood-brain-barrier.csv", "wb") do |csv|
+ CSV.read("../classification/bbp2.smi",{:col_sep => "\t"}).each do |line|
+ smi = line.first
+ act = line[-2]
+ p smi, act
+ if act =~ /p/i
+ csv << [smi, "penetrating"]
+ elsif act =~ /n/i
+ csv << [smi, "nonpenetrating"]
+ else
+ p "unknown act '#{act}'"
+ end
+ end
+end
+
diff --git a/scripts/modena2lazar.rb b/scripts/modena2lazar.rb
new file mode 100644
index 0000000..801106b
--- /dev/null
+++ b/scripts/modena2lazar.rb
@@ -0,0 +1,31 @@
+require_relative '../../lazar/lib/lazar'
+include OpenTox
+
+descriptors = ["Material","Coating","Primary size 1st Dimension [nm]","Primary size 2nd Dimension [nm]","Aspect ratio","Surface area [m2/g]","Zeta potential [mV]","Size in situ [nm]"]
+
+conditions = ["Assay","Treatment time","Cell type","Serum concentration","Dispersion protocol"]
+endpoints = ["EC25 (ug/ml)","EC50 (ug/ml)","slope EC50 (ug/ml)","EC25 (mm2/ml)","EC50 (mm2/ml)","slope EC50 (surface area)","EC25 (10E12 particles/ml)","EC50 (10E12 particles/ml)","slope EC50 (number)"]
+
+descriptor_csv = CSV.open("../regression/MODENA-descriptors.csv", "wb")
+#endpoint_csvs
+#endpoins.each do |e|
+
+#descriptor_csv << ["ID"]+descriptors
+input = CSV.read("../src/MODENA-EC50_EC25.csv")
+header = input.shift
+descriptor_indices = descriptors.collect{|d| header.index d}
+condition_indices = conditions.collect{|c| header.index c}
+condition_parameters = []
+condition_counts = {}
+input.each do |line|
+ id = line[0]+"_"+line[1].gsub(" ","_")
+ #descriptor_csv << [id]+descriptor_indices.collect{|i| line[i]}
+ conds = condition_indices.collect{|i| line[i]}
+ condition_parameters << conds
+ condition_counts[conds] ||= 0
+ condition_counts[conds] += 1
+end
+#descriptor_csv.close
+p condition_parameters.size
+p condition_parameters.uniq.size
+p condition_counts.sort{|a,b| b.last <=> a.last}
diff --git a/src/bbp2.smi b/src/bbp2.smi
new file mode 100644
index 0000000..6cb0c19
--- /dev/null
+++ b/src/bbp2.smi
@@ -0,0 +1,415 @@
+c12c(c(ccc1)Cl)C(N(Cc1n2cnc1c1nc(on1)[C@](CO)(C)O)C)=O 1 35 n 1
+NCCc1cn2c(n1)cccc2 2 1-47 n 1
+CCCN(CCC)CCc1ccc(c2c1CC(N2)=C)O 3 1-48 p 1
+c1(c2c(cc(F)cc2)on1)C1CCN(CCc2c(n3c([C@@H](CCC3)O)nc2C)=O)CC1 4 9-OH-risperidone p 1
+c12c(C(c3ccccc3)=NCc3n1c(nn3)C)cc(Cl)cc2 5 Alprazolam p 1
+C1(\c2c(CCc3c1cccc3)cccc2)=C\CCN(C)C 6 Amitriptyline p 1
+c12c(ncnc1O)[nH]nc2 7 Allopurinol p 1
+n1(c2ccccc2)n(c(C)cc1=O)C 8 Antipyrine p 1
+c1(c(cccc1)OC(C)=O)C(O)=O 9 Aspirin p 1
+N(C(NCCCl)=O)(CCCl)N=O 10 BCNU p 1
+c12c(n(c(=O)n(c1=O)C)C)ncn2C 11 Caffeine p 1
+N1(c2c(cccc2)C=Cc2c1cccc2)C(N)=O 12 Carbamazepine p 1
+c1(N(CCCl)CCCl)ccc(CCCC(O)=O)cc1 13 Chlorambucil n 1
+N1(c2c(Sc3c1cccc3)ccc(c2)Cl)CCCN(C)C 14 Chlorpromazine p 1
+c1(c([nH]cn1)C)CSCCN\C(=[NH]\C#N)NC 15 Cimetidine n 1
+c1(NC=2NCCN2)c(cccc1Cl)Cl 16 Clonidine p 1
+c12[C@]34[C@@H]5[C@H]([N@@](C)CC4)Cc2ccc(c1O[C@H]3[C@@H](O)C=C5)OC 17 Codeine p 1
+N1(c2c(CCc3c1cccc3)cccc2)CCCNC 18 Desipramine p 1
+n1(c2c(c(ncn2)O)nc1)[C@@H]1O[C@H](CO)CC1 19 Didanosine n 1
+n1(c2c(cc(Cl)cc2)[nH]c1=O)C1CCN(CCCn2c3c(cccc3)[nH]c2=O)CC1 20 Domperidone p 1
+N1([C@@H](c2ccc(Cl)cc2)c2ccccc2)CCN(CCOCCO)CC1 21 Hydroxyzine p 1
+c1([C@@H](C(O)=O)C)ccc(CC(C)C)cc1 22 Ibuprofen p 1
+c1c(c(ncc1)CCCCNc1nc(c(c[nH]1)Cc1ccc(nc1)C)=O)OC 23 Icotidine n 1
+N1(c2c(CCc3c1cccc3)cccc2)CCCN(C)C 24 Imipramine p 1
+c12c(c(CC(O)=O)c(n1C(c1ccc(Cl)cc1)=O)C)cc(OC)cc2 25 Indometacin n 1
+c12c(C(N(Cc3n1cnc3c1noc(n1)C(C)C)C)=O)c(ccc2)Cl 26 L-663581 p 1
+CN(C)Cc1ccc(CSCCNc2nc(=O)c(Cc3ccc(C)nc3)c[nH]2)o1 27 Lupitidine n 1
+N(c1ccccn1)(Cc1ccc(OC)cc1)CCN(C)C 28 Mepyramine p 1
+N12[C@H](c3c(cccc3)Cc3c1cccc3)C[N@](C)CC2 29 Mianserin p 1
+c12c(C(c3c(cccc3)F)=NCc3n1c(nc3)C)cc(Cl)cc2 30 Midazolam p 1
+N12[C@H](c3c(cccc3)Cc3c1nccc3)C[N@](C)CC2 31 Mirtazapine p 1
+N1(c2c(NC(c3c1nccc3)=O)c(ccn2)C)C1CC1 32 Nevirapine p 1
+C1NCCN(C1)c1ccc(c(n1)Cl)C(F)(F)F 33 Org12962 p 1
+c1c2c(cc(c1)Cl)[C@@H]1[C@H](c3ccccc3O2)CNC1 34 Org30526 p 1
+c1c2c(ccc1)[C@@]1([C@@H](c3cccc(c3O2)C)CNCC1)O 35 Org32104 p 1
+c1ccc(c(c1)[C@H](CC=C)N)c1c2c(on1)cccc2 36 Org34167 p 1
+c1c2c(ccc1)[C@@]1([C@@H](c3cccc(c3O2)C)C[N@](CC1)C)O 37 Org4428 p 1
+c1c2c(cc(c1)Cl)[C@@H]1[C@H](c3ccccc3O2)CN(C1)C 38 Org5222 p 1
+c12C(c3ccccc3)=N[C@H](O)C(Nc1ccc(c2)Cl)=O 39 Oxazepam p 1
+c1(oc([CH2+]SCCN\C(=C\[N+](=O)[O-])NC)cc1)CN(C)C 40 Ranitidine n 1
+c1(c2c(cc(F)cc2)on1)C1CCN(CCc2c(n3c(CCCC3)nc2C)=O)CC1 41 Risperidone p 1
+C1(C(NC(=[O-])NC1=O)=O)([C@H](CCC)C)[CH-]C 42 Pentobarbital p 1
+c12[C@]3([C@H]([N@](C)CC3)N(c1ccc(c2)OC(Nc1ccccc1)=O)C)C 43 Phenserine p 1
+c12[C@]3([C@@H](N(C)c1ccc(c2)OC(NC)=O)[N@](C)CC3)C 44 Physostigmine p 1
+N1(c2c(Sc3c1cccc3)cccc2)CCCN(C)C 45 Promazine p 1
+c1(c(cccc1)O)C(O)=O 46 Salicylicacid n 1
+c1c(c(ncc1Br)CCCCNc1nc(c(c[nH]1)Cc1ccc(nc1)C)=O)C 47 Temelastine n 1
+c12c(n(c(=O)n(c1=O)C)C)nc[nH]2 48 Theophylline p 1
+N1(c2c(Sc3c1cccc3)ccc(c2)SC)CC[C@H]1[N@@](CCCC1)C 49 Thioridazine p 1
+C1[C@H]2[C@H]3[C@@H](C4=C(CC(=O)CC4)C[C@H]3C)CC[C@@]2([C@@](C#C)(O)C1)C 50 Tibolone p 1
+c1(nc(NC(N)=[NH2])sc1)CSCCN\C(=[NH]\C#N)NC 51 Tiotidine p 1
+C(CCC)(CCC)C(=O)[O-] 52 Valproicacid p 1
+c1([C@](CCC[N@](CCc2cc(c(OC)cc2)OC)C)(C(C)C)C#N)cc(c(OC)cc1)OC 53 Verapamil p 1
+C1CN(CCC1)Cc1cccc(c1)OCCCNc1nc2c(s1)cccc2 54 Zolantidine p 1
+n12c3c(C(c4c(cccc4)F)=NCc1cnc2CO)cc(Cl)cc3 55 1-hydroxymidazolam p 2
+C(C)(Cl)(Cl)Cl 56 111-trichloroethane p 2
+C(CCl)(F)(F)F 57 111-trifluoro-2-chloroethane p 2
+CC(CCC)C 58 2-methylpentane p 2
+CC(CO)C 59 2-methylpropanol p 2
+CC(CC)(C)C 60 22-dimethylbutane p 2
+CC[C@H](CCC)C 61 3-methylhexane p 2
+CCC(CC)C 62 3-methylpentane p 2
+c12c(C(c3c(cccc3)F)=N[C@@H](c3n1c(nc3)C)O)cc(Cl)cc2 63 4-hydroxymidazolam p 2
+c1c(NC(C)=O)ccc(O)c1 64 Acetaminophen p 2
+n1(c2ccccc2)c(c(N(C)C)c(n1C)C)=O 65 Aminopyrine p 2
+C1(C(NC(=O)NC1=O)=O)(CCC(C)C)CC 66 Amobarbital p 2
+c1(ccc(CC(N)=O)cc1)OC[C@@H](CNC(C)C)O 67 Atenolol n 2
+c1ccccc1 68 Benzene p 2
+c12n(c3c(c(ccc3)Br)C(N3[C@H]1CCC3)=O)cnc2C(OC(C)(C)C)=O 69 Bretazenil p 2
+c1(C2(CCN(CCCC(c3ccc(F)cc3)=O)CC2)O)ccc(Br)cc1 70 Bromperidol p 2
+CCC(C)=O 71 Butanone p 2
+c12N(c3ccccc3)C(CC(N(c1ccc(c2)Cl)C)=O)=O 72 Clobazam p 2
+C1CCCCC1 73 Cyclohexane p 2
+C1CC1 74 Cyclopropane p 2
+N1(c2c(CCc3c1cccc3)cccc2)CCCN 75 Desmethyldesipramine p 2
+C=1(c2c(N(C)C(CN1)=O)ccc(c2)Cl)c1ccccc1 76 Diazepam p 2
+C(Cl)Cl 77 Dichloromethane p 2
+CCOCC 78 Diethylether p 2
+C=COC=C 79 Divinylether p 2
+C([C@@H](F)Cl)(OC(F)F)(F)F 80 Enflurane p 2
+C(C)O 81 Ethanol p 2
+c1(ccccc1)CC 82 Ethylbenzene p 2
+n12c3c(C(=O)N(Cc1c(C(OCC)=O)nc2)C)cc(F)cc3 83 Flumazenil p 2
+c12C(c3c(cccc3)F)=[NH+]CC(N(c1ccc(c2)[N+](=O)[O-])C)=O 84 Flunitrazepam p 2
+c12N(c3c(cccc3)Sc1ccc(c2)C(F)(F)F)CCCN1CCN(CCO)CC1 85 Fluphenazine p 2
+C(COC=C)(F)(F)F 86 Fluroxene p 2
+c1(C2(CCN(CCCC(c3ccc(F)cc3)=O)CC2)O)ccc(Cl)cc1 87 Haloperidol p 2
+C([C@@H](Cl)Br)(F)(F)F 88 Halothane p 2
+CCCCCCC 89 Heptane p 2
+CCCCCC 90 Hexane p 2
+C=1([C@]2(C(N(C(=O)NC2=O)C)=O)C)CCCCC1 91 Hexobarbital p 2
+c12ccccc2C[C@H]([C@H]1NC([C@H](Cc1ccccc1)C[C@@H](CN1[C@@H](C[N@](Cc2cccnc2)CC1)C(NC(C)(C)C)=O)O)=O)O 92 Indinavir p 2
+C([C@H](OC(F)F)Cl)(F)(F)F 93 Isoflurane p 2
+c12N(c3c(cccc3)Sc1ccc(c2)[S@@](C)=O)CC[C@H]1[N@@](CCCC1)C 94 Mesoridazine p 2
+C1([C@](C(NC(N1C)=[O-])=O)([C@@H](C#CCC)C)CC=C)=[O-] 95 Methohexital p 2
+C(C(Cl)Cl)(OC)(F)F 96 Methoxyflurane p 2
+C1(CCCC1)C 97 Methylcyclopentane p 2
+c12c3c(ccc1C[C@@H]1[C@@H]4C=C[C@@H]([C@@H]([C@]24CC[N@@]1C)O3)O)O 98 Morphine p 2
+N1(c2c(Sc3c1cccc3)ccc(c2)Cl)CCCNC 99 Nor-1-chlorpromazine p 2
+N1(c2c(Sc3c1cccc3)ccc(c2)Cl)CCCN 100 Nor-2-chlorpromazine p 2
+N1(c2c(Sc3c1cccc3)ccc(c2)SC)CC[C@H]1NCCCC1 101 Northioridazine p 2
+C1N(CCN(C1)c1cc(ccn1)C(F)(F)F)CCCCN1C(CCC1)=O 102 Org13011 p 2
+O=c1c2c([nH]c(=O)n1C)ncn2C 103 Paraxanthine p 2
+CCCCC 104 Pentane p 2
+N1(N(c2ccccc2)C(=O)C(C1=O)CCCC)c1ccccc1 105 Phenylbutazone p 2
+c1([C@@]2(c3ccccc3)NC(=[O-])NC2=O)cccc[c-]1 106 Phenytoin p 2
+CCCO 107 Propanol p 2
+CC(C)=O 108 Propanone p 2
+c12c(OC[C@@H](CNC(C)C)O)cccc1cccc2 109 Propranolol p 2
+c12c([C@@H]([C@@H]3[N@@]4C[C@H](C=C)[C@H](C3)CC4)O)ccnc1ccc(c2)OC 110 Quinidine p 2
+c1c2c(sc1)C(N(Cc1n2cnc1C(=O)OC(C)(C)C)C)=O 111 RO19-4603 p 2
+C1C(Nc2c1c(ccc2)CCN(CCC)CCC)=O 112 SKF101468 p 2
+C1C(Nc2c1c(ccc2O)CCN(CCC)CCC)=O 113 SKF89124 p 2
+N(C(=O)c1c(O)cccc1)CC(=O)O 114 Salicyluricacid p 2
+C[N@@]1CCCC[C@H]1CCN1c2ccccc2Sc2ccc(cc12)S(C)(=O)=O 115 Sulforidazine p 2
+C([C@@H](F)Br)C(F)(F)F 116 Teflurane p 2
+c12c(c([nH]c(n1C)=O)=O)n(C)cn2 117 Theobromine p 2
+C1(C(C(NC(N1)=S)=O)([C@@H](CCC)C)CC)=O 118 Thiopental P 2
+c1(ccccc1)C 119 Toluene p 2
+c12c(C(c3c(cccc3)Cl)=NCc3n1c(nn3)C)cc(Cl)cc2 120 Triazolam p 2
+c12N(c3c(cccc3)Sc1ccc(c2)C(F)(F)F)CCCN1CCN(C)CC1 121 Trifluoperazine p 2
+C(=C\Cl)(\Cl)Cl 122 Trichloroethylene p 2
+C(Cl)(Cl)Cl 123 Trichloromethane p 2
+c1c(nccc1)CCNC 124 Y-G14 p 2
+c1c(nccc1)CCN(C)C 125 Y-G15 p 2
+n1c(scc1)CCN 126 Y-G16 p 2
+n1c(scc1c1ccccc1)CCN 127 Y-G19 n 2
+c1c(nc2n1cccc2)CCN 128 Y-G20 n 2
+n1([C@H]2C[C@H](N=[N+]=N)[C@H](O2)CO)c([nH]c(=O)c([cH+]1)C)=O 129 Zidovudine p 2
+c1c(cccc1C)C 130 m-Xylene p 2
+c1(c(cccc1)C)C 131 o-Xylene p 2
+c1(ccc(C)cc1)C 132 p-Xylene p 2
+CC(C)O 133 2-propanol p 3
+c12[C@@H]3[C@@H](c4c(cccc4)N(c1cccc2)C(N)=O)O3 134 Carbamazepineepoxide p 3
+c12c(nc(c(c1C(N[C@@H](CC)c1ccccc1)=O)C)c1ccccc1)cccc2 135 SB-222200 P 3
+c1cc(ccc1CCCC(OC(C)(C)C)=O)N(CCCl)CCCl 136 Tertbutylchlorambucil P 3
+C(=C)(Cl)(Cl)Cl 137 Trichloroethene p 3
+c1(ncccc1NC(C)C)N1CCN(C(c2cc3cc(NS(C)(=O)=O)ccc3[nH]2)=O)CC1 138 Delavirdine n 4
+C(c1ccccc1)(c1ccccc1)OC1CCN(CCCC(c2ccc(C(C)(C)C)cc2)=O)CC1 139 Ebastine n 4
+N1(c2c(NC(c3c1cccc3)=O)cccn2)C(CN1CCN(C)CC1)=O 140 Pirenzepine p 4
+c12c(Sc3c(N1C[C@@H](N(C)C)C)cccc3)cccc2 141 Promethazine P 4
+s1cc(CSCCN\C(NC)=[NH]\C#N)nc1\[NH]=C(\N)N 142 38508 p 4
+c1cc(c2nc(sc2)CCN)ccc1 143 22767 n 4
+c1cc(CCNC)ncc1 144 24228 p 4
+c1cc(CCN(C)C)ncc1 145 24593 p 4
+s1c(ncc1)CCN 146 24959 p 4
+c1nc(C2CCN(CC2)C(NC2CCCCC2)=S)c[nH]1 147 25324 p 4
+c1ccc2Oc3c(cc(cc3)Cl)[C@@H]3[C@@H](c2c1)C[N@](CC3)C 148 7-K06 p 5
+c1c(Cl)nc(N2CCN(CCCCN3C(CCC3)=O)CC2)cc1C(F)(F)F 149 7-K08 p 5
+c1ccc2Oc3c(cc(cc3)Cl)[C@@H]3[C@@H](c2c1)CNCC3 150 7-K10 p 5
+c1c(c(ncc1)CSCCN\C(=[NH]\C#N)NCC)Br 151 12 n 6
+c1cc(ncc1)CSCCNc1c(cc[nH]1)[N+](=O)[O-] 152 14 p 6
+c1(cc(nc(c1C)C)C(SC(CNc1c(cc[nH]1)[N+](=O)[O-])(C)C)(C)C)C 153 15 p 6
+n1c(csc1\[NH]=C(\N)N)c1ccccc1 154 16 p 6
+n1c(csc1\[NH]=C(\N)N)c1cccc(c1)N 155 17 n 6
+n1c(csc1\[NH]=C(\N)N)c1cccc(c1)NC(C)=O 156 18 n 6
+n1c(csc1\[NH]=C(\N)N)c1cccc(c1)N\C(NC)=[NH]\C#N 157 19 n 6
+s1cc(nc1\[NH]=C(\N)N)C 158 2 p 6
+c1(c(oc(c1C)C(N(C(C)(N)C)C(N)(C)C)(C)C)C)C.C[NH+]O.[OH-] 159 22 p 6
+[NH]C(CC(C)C([N@@](C(C)(C)C)C(N)(C)N)(C)C)c1c(c(c[nH+][o+]1)C)[O-] 160 23 p 6
+C1CN(CCC1)Cc1cccc(c1)OCCCNC(=O)C 161 24 p 6
+C1CN(CCC1)Cc1cccc(c1)OCCCNC(=O)c1ccccc1 162 25 p 6
+C1CN(CCC1)Cc1cccc(c1)OCCCO 163 26 p 6
+C1CN(CCC1)Cc1cccc(c1)OCCCNc1ncccc1 164 27 p 6
+C1CN(CCC1)Cc1cccc(c1)OCCCNc1nccs1 165 28 p 6
+C1CN(CCC1)Cc1cccc(c1)OCCCNc1nc2c(o1)cccc2 166 30 p 6
+c1c(oc(c1)CN(C)C)CSCCNc1nc(c(c[nH]1)Cc1cc2c(cc1)cccc2)=O 167 4 n 6
+CN(C)Cc1oc(cc1)CSCCNC=1NC=C(CN1)Cc1cnc(cc1)C 168 38480 n 6
+c1(nccc(c1)c1nc([nH]n1)N)N(C)C 169 BBcpd10 n 6
+n1(c(c2nc[nH]c2n(c1=O)C)=O)C 170 9-C1 p 7
+c1c2CCOc2c(cc1OC)CN[C@@H]1CCCN[C@H]1c1ccccc1 171 9-C15 p 7
+c1(cc(N\C(=[NH]\c2cccc(c2)CC)C)ccc1)CC 172 9-C17 p 7
+c1(c(cc2n(ncc2c1)CCN)Cl)Cl 173 9-C7 p 7
+c12c(n([C@@H]3C[C@H](CO)C=C3)cn2)nc(N)nc1NC1CC1 174 Abacavir p 8
+c1(c(cc(NC(CCC)=O)cc1)C(C)=O)OC[C@@H](CNC(C)C)O 175 Acebutolol p 8
+c12c(ncn1COCCO)c([nH]c(n2)N)=O 176 Aciclovir p 8
+c12c(nc([nH]1)NC(OC)=O)cc(SCCC)cc2 177 Albendazole p 8
+C12(CC3CC(C1)CC(C2)C3)N 178 Amantadine p 8
+c1(ccccc1)C[C@H](C)N 179 Amfetamine p 8
+S(CCNCCCN)P(O)(O)=O 180 Amifostine n 8
+O([C@H]1[C@@H](C[C@H](N)[C@H]([C@@H]1O)O[C@H]1O[C@@H]([C@@H](O)[C@@H]([C@H]1O)O)CN)NC([C@H](CCN)O)=O)[C@H]1O[C@@H]([C@@H](O)[C@@H]([C@H]1O)N)CO 181 Amikacin p 8
+c1(c(cc(N)cc1)O)C(O)=O 182 Aminosalicylicacid n 8
+n1([C@@H]2O[C@H](CO)[C@H]([C@H]2O)O)c(nc(N)cc1)=O 183 Cytarabine p 8
+c1(c(nc[nH]1)C(N)=O)\N=N\N(C)C 184 Dacarbazine p 8
+c12c([C@H](C[C@@](C2)(C(C)=O)O)O[C@H]2C[C@@H]([C@H](O)[C@@H](O2)C)N)c(c2C(c3c(cccc3C(c2c1O)=O)OC)=O)O 185 Daunorubicin n 8
+C1[C@@H]2[C@](C(=C3C(c4c(ccc(c4[C@H]([C@@H]13)O)Cl)O)=O)O)(C(C(C(N)=O)=C([C@H]2N(C)C)O)=O)O 186 Demeclocycline n 8
+Clc1ccc2NC(=O)CC(=O)N(c3ccccc3)c2c1 187 Desmethylclobazam p 8
+C=1(c2c(NC(CN1)=O)ccc(c2)Cl)c1ccccc1 188 Desmethyldiazepam p 8
+N1(c2c(Sc3c1cccc3)cccc2)CCCNC 189 Desmonomethylpromazine p 8
+N1(C[C@@H](N2CC(NC(C2)=O)=O)C)CC(NC(C1)=O)=O 190 Dexrazoxane n 8
+c12[C@@]34[C@@H]([C@H]([N@@](C)CC3)Cc1ccc(c2)OC)CCCC4 191 Dextromethorphan p 8
+N12[C@]([C@@H]3CCCN3C([C@@H]1Cc1ccccc1)=O)(OC(NC([C@@H]1C[C@@H]3c4c5c(c[nH]c5ccc4)C[C@H]3[N@@](C1)C)=O)(C)C2=O)O 192 Dihydroergotamine n 8
+N(C(SSC(N(CC)CC)=S)=S)(CC)CC 193 Disulfiram p 8
+c12c([C@H](C[C@@](C2)(C(CO)=O)O)O[C@H]2C[C@@H]([C@H](O)[C@@H](O2)C)N)c(c2C(c3c(cccc3C(c2c1O)=O)OC)=O)O 194 Doxorubicin n 8
+C=1([C@]2([C@H]([C@@H](C(O)=C(C2=O)C(N)=O)N(C)C)[C@H]([C@@H]2[C@H](c3cccc(c3C(C12)=O)O)C)O)O)O 195 Doxycycline p 8
+c12[C@](C#CC3CC3)(OC(=O)Nc1ccc(c2)Cl)C(F)(F)F 196 Efavirenz n 8
+N1([C@@H](CCC1)C(O)=O)C([C@@H](N[C@@H](CCc1ccccc1)C(OCC)=O)C)=O 197 Enalapril n 8
+c1(cc(c(O)cc1)O)[C@H](CNC)O 198 Epinephrine n 8
+c1(c(c(c(OCC(O)=O)cc1)Cl)Cl)C(C(CC)=C)=O 199 Etacrynicacid n 8
+N([C@H](CC)CO)CCN[C@H](CC)CO 200 Ethambutol n 8
+c1(cc(ncc1)CC)C(N)=S 201 Ethionamide p 8
+C1([C@@](CC(=O)N1)(CC)C)=O 202 Ethosuximide p 8
+c12[C@H]([C@@H]3[C@H](COC3=O)[C@@H](c1cc1OCOc1c2)O[C@@H]1O[C@H]2[C@@H](O[C@H](C)OC2)[C@@H]([C@H]1O)O)c1cc(c(O)c(c1)OC)OC 203 Etoposide n 8
+c1(nc(CSCC\C(=[NH]\S(N)(=O)=O)N)cs1)\[NH]=C(\N)N 204 Famotidine p 8
+c1(C(Cn2cncn2)(Cn2cncn2)O)c(cc(F)cc1)F 205 Fluconazole p 8
+P(C(=O)O)(=O)(O)O 206 Foscarnetsodium p 8
+C1(CC(O)=O)(CCCCC1)CN 207 Gabapentin p 8
+N12[C@@H]([C@@H](NC(c3c4c(ccc3OCC)cccc4)=O)[C-]2=O)SC([C@@H]1C(=O)O)(C)C 208 Nafcillin n 8
+c12c(c(c(C(O)=O)cn1CC)=O)ccc(n2)C 209 Nalidixicacid n 8
+C1[C@@H]2CCCC[C@@H]2C[N@](C[C@H]([C@@H](NC(c2c(c(ccc2)O)C)=O)CSc2ccccc2)O)[C@@H]1C(NC(C)(C)C)=O 210 Nelfinavir n 8
+N1(c2c(Sc3c1cccc3)ccc(c2)SC)CC[C@H]1NCCCC1 211 Norepinephrine n 8
+c12c([nH]c(n1)[S@@](Cc1c(c(c(C)cn1)OC)C)=O)ccc(c2)OC 212 Omeprazole n 8
+N12[C@@H]([C@@H](NC(c3c(c4ccccc4)noc3C)=O)[C-]2=O)SC([C@@H]1C(=O)O)(C)C 213 Oxacillin n 8
+c1(ccc(O)cc1)NC(C)=O 214 Paracetamol p 8
+c12[C@]3([C@H]([C@H]([N@@](C\C=C(\C)C)CC3)Cc1ccc(c2)O)C)C 215 Pentazocine p 8
+n1(c2c([C@@H](CNC=N2)O)nc1)[C@@H]1O[C@H](CO)C(C1)O 216 Pentostatin p 8
+C1(c2ccccc2)(C(OCC)=O)CCN(C)CC1 217 Pethidine p 8
+c1(c(nc(N)cc1)N)\N=N\c1ccccc1 218 Phenazopyridine n 8
+C1(c2ccccc2)(C(NC(=O)NC1=O)=O)CC 219 Phenobarbital p 8
+N12[C@@H]([C@@H](NC(COc3ccccc3)=O)[C-]2=O)SC([C@@H]1C(=O)O)(C)C 220 Phenoxymethylpenicillin n 8
+c12c([nH]cc2)cccc1OC[C@@H](CNC(C)C)O 221 Pindolol p 8
+c12c(C[C@@H]([C@@H](C([C@H]([C@@H](C)O)O)=O)OC)[C@@H](C1=O)OC1C[C@@H](O[C@H]3C[C@@H](O[C@H]4C[C@]([C@H](O)[C@H](O4)C)(C)O)[C@H](O)[C@H](O3)C)[C@H](O)[C@H](O1)C)cc1cc(O[C@H]3C[C@@H](O[C@H]4C[C@H]([C@H](O)[C@H](O4)C)O)[C@@H](O)[C@H](O3)C)c(c(c1c2O)O)C 222 Plicamycin p 8
+C=12[C@@H]([C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)[C@H](C[C@@H](O)C1)OC([C@H](CC)C)=O 223 Pravastatin n 8
+c12[C@@H]3N(C(CN(C3)C(C3CCCCC3)=O)=O)CCc1cccc2 224 Praziquantel p 8
+c1(S(N(CCC)CCC)(=O)=O)ccc(C(O)=O)cc1 225 Probenecid n 8
+c1(Cc2c(nc(N)nc2)N)cc(c(OC)c(c1)OC)OC 226 Trimethoprim p 8
+c12c(ccc(CNc3cc(c(OC)c(c3)OC)OC)c1C)nc(N)nc2N 227 Trimetrexate n 8
+C(CO)(CO)(CO)N 228 Trometamol n 8
+c12n(c3c(cc(F)cc3)F)cc(C(O)=O)c(c1cc(F)c(n2)N1C[C@@H]2C(N)[C@H]2C1)=O 229 Trovafloxacin p 8
+C(N)(N)=O 230 Urea p 8
+C=1(C2CCC(c3ccc(Cl)cc3)CC2)C(c2c(cccc2)C(C1O)=O)=O 231 Atovaquone n 8
+C1(C[C@@H]2N(C)[C@H](C1)CC2)OC([C@H](c1ccccc1)CO)=O 232 Atropine p 8
+C(CCCCCCCC(O)=O)(O)=O 233 Azelaicacid n 8
+O([C@H]1[C@@H]([C@@H](O[C@@H]2C[C@]([C@@H](O)[C@@H](O2)C)(OC)C)[C@@H](C(O[C@@H]([C@](C)(O)C([C@H]([N@@](C[C@@H](C[C@@]1(C)O)C)C)C)O)CC)=O)C)C)[C@H]1[C@@H]([C@H](C[C@H](O1)C)N(C)C)O 234 Azithromycin n 8
+C([C@@H]1C(N[C@@H](Cc2c[nH]cn2)C(N[C@@H](C(N[C@H](C(=O)N[C@H](C(N[C@@H](C(N[C@H](C(N1)=O)[C@H](CC)C)=O)CCCN)=O)CCCCNC([C@@H](NC([C@H](NC([C@@H](NC([C@H]1N=C([C@@H]([C@@H](CC)C)N)SC1)=O)CC(C)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CC(N)=O)=O)CC(O)=O)=O)=O)c1ccccc1 235 Bacitracin n 8
+C([N+](C)(C)C)[C@@H](OC(N)=O)C 236 Bethanechol n 8
+c1(c(cccc1)Br)C[N+](CC)(C)C 237 Bretyliumtosilate n 8
+N12[C@](C3N(CCC3)C([C@@H]2CC(C)C)=O)(O[C@](C1=O)(NC([C@@H]1C=C2c3c4c(c(Br)[nH]c4ccc3)C[C@H]2[N@@](C1)C)=O)C(C)C)O 238 Bromocriptine n 8
+c12[C@]34[C@@]56[C@H]([N@@](CC7CC7)CC4)Cc2ccc(c1O[C@H]3[C@](OC)([C@H](C5)[C@](C(C)(C)C)(C)O)CC6)O 239 Buprenorphine p 8
+c1(C([C@@H](NC(C)(C)C)C)=O)cc(ccc1)Cl 240 Bupropion p 8
+O(S(C)(=O)=O)CCCCOS(C)(=O)=O 241 Busulfan p 8
+N12[C@@H]([C@@H](NC([C@H](c3ccccc3)C(=O)O)=O)[C-]2=O)SC([C@@H]1C(=O)O)(C)C 242 Carbenicillin p 8
+N(C(NCCCl)=O)(CCCl)N=O 243 Carmustine p 8
+N12[C@H]([C@@H](NC([C@H](C=3CC=CCC3)N)=O)C1=O)SCC(=C2C(O)=O)C 244 Cefradine n 8
+C1([C@H]([C@H](NC(C(Cl)Cl)=O)CO)O)CCC([N+](=O)=[O-])C[CH+]1 245 Chloramphenicol p 8
+c12c(nccc1N[C@@H](CCCN(CC)CC)C)cc(Cl)cc2 246 Chloroquine p 8
+c12c(cc(Cl)c(c1)S(N)(=O)=O)N=CNS2(=O)=O 247 Chlorothiazide n 8
+c1(c(cc(N)c(c1)Cl)OC)C(N[C@@H]1[C@H](C[N@@](CCCOc2ccc(F)cc2)CC1)OC)=O 248 Cisapride p 8
+n1(c2c(c(nc(n2)Cl)N)nc1)[C@@H]1O[C@H](CO)C(C1)O 249 Cladribine p 8
+C(c1ccccc1)([C+]1CCCCC1)(C(O[C@@H]1C2CC[N+](C1)(C)CC2)=O)O 250 Clidiniumbromide n 8
+n1(c2c(nc3c1cccc3)cc(Nc1ccc(Cl)cc1)c(\c2)=N/C(C)C)c1ccc(Cl)cc1 251 Clofazimine n 8
+N1(c2c(CCc3c1cccc3)ccc(c2)Cl)CCCN(C)C 252 Clomipramine p 8
+c12c3c([C@@H](NC(C)=O)CCc2cc(c(c1OC)OC)OC)cc(=O)c(cc3)OC 253 Colchicine n 8
+c12c(oc(C(=O)O)cc2=O)cccc1[O-]CC(COc1c2c(oc(C(=O)O)cc2=O)ccc1)O 254 Cromoglicicacid n 8
+C1([C@@H](CON1)N)=O 255 Cycloserine p 8
+[c-]12c(nc[n+]1COC(CO)CO)c(=[O-])[nH]c(n2)N 256 Ganciclovir p 8
+c12c(cc(Cl)c(c1)S(N)(=O)=O)NCNS2(=O)=O 257 Hydrochlorothiazide n 8
+C(NO)(N)=O 258 Hydroxycarbamide p 8
+[N+]1([C@H]2CC(OC([C@H](c3ccccc3)CO)=O)C[C@@H]1CC2)(C(C)C)C 259 Ipratropiumbromide n 8
+c1(C(NN)=O)ccncc1 260 Isoniazid p 8
+c1([C@]2(O[C@H](COc3ccc(N4CCN(c5ccc(n6c(n([C@@H](CC)C)nc6)=O)cc5)CC4)cc3)CO2)Cn2cncn2)c(cc(Cl)cc1)Cl 261 Itraconazole n 8
+C1([C@@H](O[C@H]2O[C@@H]([C@@H](O)[C@@H]([C@H]2O)N)CO)[C@@H](C[C@@H]([C@H]1O[C@H]1O[C@@H]([C@@H](O)[C@@H]([C@H]1O)O)CN)N)N)O 262 Kanamycin n 8
+c1([C@@]2(O[C@@H](COc3ccc(N4CCN(C(C)=O)CC4)cc3)CO2)Cn2ccnc2)c(cc(Cl)cc1)Cl 263 Ketoconazole n 8
+c1(cc(ccc1)[C@@H](C(O)=O)C)C(c1ccccc1)=O 264 Ketoprofen p 8
+n12c([C@H](C(O)=O)CC2)ccc1C(c1ccccc1)=O 265 Ketorolac n 8
+c12c3c(N4CCN(C)CC4)c(F)cc1c(c(C(O)=O)cn2[C@@H](C)CO3)=O 266 Levofloxacin p 8
+O[C@@H]([C@@H]([C@@H](CO)O)O)[C@@H](CO)O 267 Mannitol n 8
+[C+](c1ccccc1)(c1ccccc1)(C(O[C@@H]1C[N+](CCC1)(C)C)=O)O 268 Mepenzolatebromide n 8
+c1(cc(ccc1)O)[C@H]([C@H](C)N)O 269 Metaraminol n 8
+c12c(ncc(n1)CN(c1ccc(C(N[C@@H](CCC(O)=O)C(O)=O)=O)cc1)C)nc(N)nc2N 270 Methotrexate n 8
+c1(ccc(CCOC)cc1)OC[C@@H](CNC(C)C)O 271 Metoprolol p 8
+n1(c(cnc1C)[N+](=O)=[O-])CCO 272 Metronidazole p 8
+C1=2[C@H]([C@H]3[C@]([C@@](C#CC)(O)CC3)(C)C[C@@H]1c1ccc(N(C)C)cc1)CCC=1C2CCC(C1)=O 273 Mifepristone n 8
+C1[C@@H]2[C@](C(=C3C(c4c(ccc(c4C[C@@H]13)N(C)C)O)=O)O)(C(C(C(N)=O)=C([C@H]2N(C)C)O)=O)O 274 Minocycline p 8
+c1(C(NCCN2CCOCC2)=O)ccc(Cl)cc1 275 Moclobemide p 8
+C1(c2c(Oc3c1cccc3)cccc2)C(OCC[N+](C(C)C)(C(C)C)C)=O 276 Propanthelinebromide n 8
+c1(cnccn1)C(N)=O 277 Pyrazinamide p 8
+c1(OC(N(C)C)=O)c[n+](ccc1)C 278 Pyridostigminebromide p 8
+c1(c2ccc(Cl)cc2)c(nc(N)nc1N)CC 279 Pyrimethamine p 8
+c12c([C@H]([C@H]3[N@@]4C[C@H](C=C)[C@H](C3)CC4)O)ccnc1ccc(c2)OC 280 Quinine n 8
+n1([C@@H]2O[C@H](CO)[C@H]([C@H]2O)O)nc(C(N)=O)cn1 281 Ribavirin p 8
+C([C@@H](C[C@@H]([C@H](Cc1ccccc1)NC(OCc1cncs1)=O)O)NC([C@@H](NC(N(Cc1nc(C(C)C)sc1)C)=O)C(C)C)=O)c1ccccc1 282 Ritonavir n 8
+C1[N@]([C@@H](C[C@@H]2CCCC[C@H]12)C(NC(C)(C)C)=O)C[C@H]([C@H](Cc1ccccc1)NC([C@@H](NC(c1nc2c(cccc2)cc1)=O)CC(N)=O)=O)O 283 Saquinavir n 8
+C(C(F)(F)F)(C(F)(F)F)OCF 284 Sevoflurane p 8
+C1(C(C(C(I)[C-](C1I)NC(C)=O)C(=O)O)I)NC(C)=O 285 Sodiumamidotrizoate n 8
+c1([C@@H](CNC(C)C)O)ccc(NS(C)(=O)=O)cc1 286 Sotalol p 8
+n1([C@@H]2O[C@H](CO)C=C2)c([nH]c(=O)c(c1)C)=O 287 Stavudine p 8
+O([C@@H]1[C@]([C@H](C)O[C@H]1O[C@H]1[C@@H]([C@H]([C@H](NC(N)=[NH2])[C@H]([C@@H]1O)O)O)NC(N)=[NH2])(C=O)O)[C@H]1[C@H]([C@@H]([C@@H](O)[C@@H](O1)CO)O)NC 288 Streptomycin n 8
+c1(S(Nc2ncccn2)(=O)=O)ccc(N)cc1 289 Sulfadiazine p 8
+c1(S(Nc2c(c(C)no2)C)(=O)=O)ccc(N)cc1 290 Sulfafurazole p 8
+c1(S(Nc2cc(C)on2)(=O)=O)ccc(N)cc1 291 Sulfamethoxazole p 8
+c12c(c(c3CCCCc3n1)N)cccc2 292 Tacrine p 8
+C(=C(/c1ccccc1)CC)(\c1ccc(OCCN(C)C)cc1)c1ccccc1 293 Tamoxifen p 8
+c12C(c3ccccc3)=N[C@@H](O)C(N(c1ccc(c2)Cl)C)=O 294 Temazepam p 8
+N12[C@@H]([C@@H](NC([C@@H](c3ccsc3)C(=O)O)=O)C2=O)SC(C)(C)[C@@-]1C(=O)O 295 Ticarcillin p 8
+c12c(c(n3Cc4c(c3c2)nc2ccc(c(c2c4)CN(C)C)O)=O)COC([C@@]1(CC)O)=O 296 Topotecan p 8
+n1([C@@H]2O[C@H](CO)CC2)c(nc(N)cc1)=O 297 Zalcitabine p 8
+c12c(noc1cccc2)CS(N)(=O)=O 298 Zonisamide p 8
+C(=O)(O)[C@@H]1[C@@H]2O[C@@](C[C@H]1O)(O)C[C@H](O)C[C@H](O)[C@H](O)CC[C@H](O)C[C@@H](O)CC(=O)O[C@H](C)[C@H](C)[C@@H]([C@H](C=CC=CC=CC=CC=CC=CC=C[C@@H](C2)O[C@@H]1[C@@H](O)[C@H](N)[C@H]([C@@H](O1)C)O)C)O 299 AmphotericinB n 8
+C(=O)N1c2c(NC[C@H]1CNc1ccc(cc1)C(N[C@@H](CCC(=O)[O-])C([O-])=O)=O)nc(nc2O)N 300 Calcium-folinate p 8
+[N-]12[C@H](SCC(=C1C(=O)[O-])C[n+]1ccccc1)[C@@H](C2=O)CC(\C(c1csc(n1)N)=N/OC(C(=O)O)(C)C)=O 301 Ceftazidime p 8
+c1cccc(c1)C[C@H](C)N 302 Dexamfetamine p 8
+Nc1c(F)cnc(n1)O 303 Flucytosine p 8
+C1CCCC2(C1)O[C@H](CO2)CNC(N)=[NH2] 304 Guanadrel n 8
+O=C(N(CCCl)N=O)NC1CCCCC1 305 Lomustine p 8
+C(S([O-])(=O)=O)CS 306 Mesna n 8
+O1[C@H]([C@H](NC(N(N=O)C)=O)[C@H]([C@@H]([C@H]1CO)O)O)O 307 Streptozotocin n 8
+O=C1[C@@H]2[C@H](c3c([C@@H]([C@H]2CO1)O[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]1O)O)O[C@H](OC2)c1cccs1)cc1c(c3)OCO1)c1cc(OC)c(c(c1)O)O 308 Teniposide p 8
+P(=S)(N1CC1)(N1CC1)N1CC1 309 Thiotepa p 8
+c12cc3cc(c1O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1C[C@]([C@H]([C@@H](O1)C)O)(C)N)Oc1c(cc([C@H]([C@H](C(N[C@H](C(N[C@H]3C(N[C@H]3C(N[C@@H]([C@@H](c4cc(c(O2)cc4)Cl)O)C(N[C@H](C(O)=O)c2cc(O)cc(O)c2c2cc3ccc2O)=O)=O)=O)=O)CC(N)=O)=O)NC([C@H](NC)CC(C)C)=O)O)cc1)Cl 310 Vancomycin n 8
+n1cnc2c(c1N)ncn2[C@H]1[C@@H]([C@@H]([C@H](O1)CO)O)O 311 Vidarabine p 8
+CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F 312 trifluopromazine p 8
+c1(NCCSCc2oc(cc2)CN(C)C)[nH]cc(c1N(=O)=O)Cc1ccccc1 313 BBcpd60 p 9
+c12c(C(N(Cc3n1cnc3c1noc(n1)C(CO)(CO)C)C)=O)c(ccc2)Cl 314 Bis-hydroxylated-L-663581 n 9
+Cc1nc(sc1)\[NH]=C(\N)N 315 ICI17148 p 9
+c12c(C(N(Cc3n1cnc3c1noc(n1)C(O)(C)C)C)=O)c(ccc2)Cl 316 Mono-hydroxylated-L-663581 n 9
+C1C(CCN(C1)C(NC1CCCCC1)=S)c1c[nH]cn1 317 Thioperamide p 9
+C([C@@](C(O)=O)(NN)C)c1cc(c(O)cc1)O 318 Carbidopa n 10
+c1(ccc(O)c(c1)O)CCN 319 Dopamine n 10
+c1(c(ccc(c1)C[C@@H](C(O)=O)N)O)O 320 Levodopa p 10
+c12c(c(cc(n2)C(F)(F)F)[C@@H]([C@H]2CCCCN2)O)cccc1C(F)(F)F 321 Mefloquine p 10
+c12c3c(N4CCN(C)CC4)c(F)c(c1c(ccn2[C@H](C)CO3)=O)C(O)=O 322 Ofloxacin p 10
+c1(ccc2C(=NC[C@@H](N(C)c2c1)CNC(c1ccc(cc1)C)=O)c1ccc(cc1)F)C 323 Tifluadom p 10
+C1C(C=C2[C@](C1)([C@@H]1[C@@H](CC2)[C@H]2[C@](C[C@@H]1O)([C@H](CC2)C(CO)=O)C=O)C)=O 324 aldosterone n 10
+C[N@]1CCc2cccc3c2[C@@H]1Cc1ccc(O)c(O)c31 325 apomorphine_r p 10
+c1ccc2c(c1)n(c(n2)NC1CCN(CC1)CCc1ccc(cc1)OC)Cc1ccc(cc1)F 326 astemizole n 10
+c1(cc(c(cc1)Cl)Cl)CC(N1CCCC[C@H]1CN1CCCC1)=O 327 BRL52537 p 10
+c1(cc(c(cc1)Cl)Cl)CC(N1[C@@H](c2c(CC1)cccc2)CN1CCCC1)=O 328 BRL52580 p 10
+c1(ccc(cc1)C(F)(F)F)CC(N1[C@@H](CCCC1)CN1CCCC1)=O 329 BRL52656 p 10
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)scc2)CN1CCCC1)=O 330 BRL52871 p 10
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)[nH]cn2)CN1CCCC1)=O 331 BRL52974 n 10
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)ccs2)CN1CCCC1)=O 332 BRL53080 p 10
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](CN2CCCC2)CC(CC1)(C)C)=O 333 BRL53087 p 10
+CC(C)(C(O)=O)c1ccc(cc1)C(=O)CCCN1CCC(CC1)OC(c1ccccc1)c1ccccc1 334 carebastine n 10
+c1c(ccc([C@@H](c2ccccc2)N2CCN(CC2)CCOCC(=O)O)c1)Cl 335 cetirizine n 10
+c1(c(cc2c(c1)n(cc(c2=O)C(O)=O)C1CC1)F)N1CCNCC1 336 ciprofloxacin n 10
+C1C(C=C2[C@](C1)([C@@H]1[C@@H](CC2)[C@H]2[C@](C[C@H]1O)([C@H](CC2)C(CO)=O)C)C)=O 337 corticosterone n 10
+C1C(C=C2[C@](C1)([C@@H]1[C@@H](CC2)[C@H]2[C@](C[C@@H]1O)([C@](CC2)(C(CO)=O)O)C)C)=O 338 cortisol n 10
+c1cn(CCO)c(CC)c(O)c1=O 339 cp102 n 10
+c1cn(CCCCO)c(CC)c(O)c1=O 340 cp107 n 10
+c1cn(c(c(c1=O)O)C)C 341 cp20 p 10
+c1cn(CC)c(c(c1=O)O)C 342 cp21 p 10
+c1cn(CCCC)c(C)c(O)c1=O 343 cp24 p 10
+c1cn(CCCCCC)c(C)c(O)c1=O 344 cp25 p 10
+c1cn(CCCCC)c(C)c(O)c1=O 345 cp29 p 10
+c1cn(CCCO)c(C)c(O)c1=O 346 cp41 n 10
+c1cn(CC)c(CC)c(c1=O)O 347 cp94 p 10
+C[C@]12c3c(C[C@H]([C@H]1C)[N@](CC2)CC1CC1)ccc(c3)O 348 Cyclazocine p 10
+CN1CCN(CC1)c1cc2n(cc(C(O)=O)c(=O)c2cc1F)c1ccc(F)cc1 349 difloxacin n 10
+O(C(c1ccccc1)c1ccccc1)CCN(C)C 350 diphenhydramine p 10
+CN(C)CCO[C@@](C)(c1ccccc1)c1ccccn1 351 doxylamine p 10
+c1ccc([C@H](C[N@]2CC[C@H](C2)O)N(C(Cc2ccccc2N)=O)C)cc1 352 EMD60400 n 10
+c1(c(cc2c(n1)n(cc(c2=O)C(O)=O)CC)F)N1CCNCC1 353 enoxacin n 10
+c1cc2c(cc1O)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2O)C 354 estradiol p 10
+CN1CCN(CC1)c1c(F)cc2c(=O)c(cn(CCF)c2c1F)C(O)=O 355 fleroxacin n 10
+OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 356 flupentixol p 10
+C(=O)(O)c1c(NCc2ccco2)cc(c(c1)S(N)(=O)=O)Cl 357 furosemide n 10
+c1(cc(c(cc1)Cl)Cl)CC(N1[C@@H](CN2CCCC2)CN(CC1)C(=O)C)=O 358 GR85571 p 10
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)occ2)CN1CCCC1)=O 359 GR88377 p 10
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN(CC1)C(=O)OC)CN1CCCC1)=O 360 GR89696 p 10
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN(CC1)C(=O)OCC)CN1CCCC1)=O 361 GR89696_et p 10
+c1(CC(N2[C@H](CN(CC2)C(=O)OCCC)CN2CCCC2)=O)cc(c(cc1)Cl)Cl 362 GR89696_pr p 10
+c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)occ2)C[N@@]1C[C@@H](CC1)O)=O 363 GR91272 p 10
+c1(ccc(c(c1)Cl)Cl)CC(=O)N1[C@H](CN(C(=O)C)CC1)C[N@@]1C[C@H](O)CC1 364 GR94839 n 10
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)ccc(C(F)(F)F)cc1 365 GR94839_A n 10
+c1(ccc(cc1)SC)CC(N1[C@H](CN(CC1)C(=O)C)C[N@]1CC[C@H](C1)O)=O 366 GR94839_B n 10
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)cc(cc(c1)F)F 367 GR94839_C n 10
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)cc(ccc1)OC 368 GR94839_D n 10
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)ccc(N(=O)=O)cc1 369 GR94839_E n 10
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)ccc(OC)cc1 370 GR94839_F n 10
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)cc(ccc1)N(=O)=O 371 GR94839_G n 10
+c1(ccccc1)CC(N1[C@H](CN(CC1)C(=O)C)C[N@]1CC[C@H](C1)O)=O 372 GR94839_H n 10
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)ccc([S@](=O)C)cc1 373 GR94839_I n 10
+c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)ccc(S(=O)(=O)C)cc1 374 GR94839_L n 10
+CC(C)[C@@H](N(C)C(=O)Cc1ccc(c(c1)Cl)Cl)CN1CCCC1 375 ICI197067 p 10
+c1(ccccc1)[C@H](CN1CCCC1)N(C(=O)Cc1ccc(c(c1)Cl)Cl)C 376 ICI199441 p 10
+CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc1cc(C)on1 377 isoxicam n 10
+c1cc2c(cc1O)[C@]13[C@@H]([C@@H](C2)[N@@](CC=C)CC3)CCCC1 378 Levallorphan p 10
+CCn1cc(C(O)=O)c(=O)c2cc(F)c(N3CCN[C@H](C)C3)c(F)c12 379 lomefloxacin n 10
+CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 380 loperamide n 10
+C1Cc2c(\C(c3c1cc(cc3)Cl)=C1/CCN(CC1)C(=O)OCC)nccc2 381 loratadine n 10
+CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc1ncc(C)s1 382 meloxicam n 10
+c12[C@@]34[C@H]5[C@@H]([N@](CC=C)CC4)Cc2ccc(c1O[C@@H]3[C@@H](O)C=C5)O 383 Nalorphine p 10
+c12[C@@]34[C@]5([C@@H]([N@](CC6CC6)CC4)Cc2ccc(c1O[C@@H]3C(=O)CC5)O)O 384 naltrexone p 10
+c1(c(cc2c(c1)n(cc(c2=O)C(O)=O)CC)F)N1CCNCC1 385 norfloxacin n 10
+CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCN(C)CC1 386 pefloxacin n 10
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index 0000000..29b4b28
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new file mode 100644
index 0000000..1516122
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new file mode 100644
index 0000000..3260261
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new file mode 100644
index 0000000..de4fb1d
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new file mode 100644
index 0000000..1fadb35
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new file mode 100644
index 0000000..222cb1b
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new file mode 100644
index 0000000..c029bb9
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new file mode 100644
index 0000000..d070e0c
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new file mode 100644
index 0000000..3775688
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index 0000000..cda5f6f
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index 0000000..1e90930
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new file mode 100644
index 0000000..4901646
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new file mode 100644
index 0000000..12d4cbb
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new file mode 100644
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index 0000000..5ea598d
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diff --git a/src/enm/nanoparticle-NWKI-ada731e2-5e80-3cea-8a28-42e124bc110b.json b/src/enm/nanoparticle-NWKI-ada731e2-5e80-3cea-8a28-42e124bc110b.json
new file mode 100644
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diff --git a/src/enm/nanoparticle-NWKI-d0227b15-023a-3fd1-b47d-0d805a24fc95.json b/src/enm/nanoparticle-NWKI-d0227b15-023a-3fd1-b47d-0d805a24fc95.json
new file mode 100644
index 0000000..430e81a
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new file mode 100644
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new file mode 100644
index 0000000..55c6a7b
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diff --git a/src/enm/nanoparticle-XLSX-945d75a3-50b7-3655-8979-376d39096378.json b/src/enm/nanoparticle-XLSX-945d75a3-50b7-3655-8979-376d39096378.json
new file mode 100644
index 0000000..5fbb449
--- /dev/null
+++ b/src/enm/nanoparticle-XLSX-945d75a3-50b7-3655-8979-376d39096378.json
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new file mode 100644
index 0000000..4d02f8c
--- /dev/null
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diff --git a/src/enm/nanoparticle-XLSX-fa48e134-54cf-3417-a63a-6f744191cec2.json b/src/enm/nanoparticle-XLSX-fa48e134-54cf-3417-a63a-6f744191cec2.json
new file mode 100644
index 0000000..fe8981d
--- /dev/null
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new file mode 100644
index 0000000..3527ef7
--- /dev/null
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diff --git a/src/enm/study-FCSV-00573bc3-40d3-30ab-b785-af6955d501f6.json b/src/enm/study-FCSV-00573bc3-40d3-30ab-b785-af6955d501f6.json
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+ ]
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+ },
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+ {
+ "endpoint": "Log2 transformed",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-02719665-14fc-3005-8d86-43499af783ec.json b/src/enm/study-FCSV-02719665-14fc-3005-8d86-43499af783ec.json
new file mode 100644
index 0000000..533d703
--- /dev/null
+++ b/src/enm/study-FCSV-02719665-14fc-3005-8d86-43499af783ec.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-02719665-14fc-3005-8d86-43499af783ec",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ff7d2c8c-3d2f-316a-b890-6f9e7d88df4c"
+ },
+ "company": {
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
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+ "r_isUsedforMSDS": "false",
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
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+ "loValue": 14.9,
+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "Density",
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/cm^3",
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+ "loValue": 19.1
+ }
+ },
+ {
+ "endpoint": "MW",
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+ },
+ "result": {
+ "unit": "g/mol",
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+ }
+ },
+ {
+ "endpoint": "Mol/NP",
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "",
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+ "loValue": 0.0
+ }
+ },
+ {
+ "endpoint": "SA/NP",
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "cm^2/NP",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-02805afa-31cd-3de4-be08-b908a63575c6.json b/src/enm/study-FCSV-02805afa-31cd-3de4-be08-b908a63575c6.json
new file mode 100644
index 0000000..48e94a0
--- /dev/null
+++ b/src/enm/study-FCSV-02805afa-31cd-3de4-be08-b908a63575c6.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-02805afa-31cd-3de4-be08-b908a63575c6",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ed95bb69-9fa7-3a4a-b4a4-32dd947d4d1a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
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+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-02d6ae10-9b28-3d39-afc5-70cc57e11381.json b/src/enm/study-FCSV-02d6ae10-9b28-3d39-afc5-70cc57e11381.json
new file mode 100644
index 0000000..58028ae
--- /dev/null
+++ b/src/enm/study-FCSV-02d6ae10-9b28-3d39-afc5-70cc57e11381.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-02d6ae10-9b28-3d39-afc5-70cc57e11381",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-99734121-3347-3d4e-9bc6-67956450b140"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 467.795,
+ "errQualifier": "sd",
+ "errorValue": 17.443
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 9,
+ "errQualifier": "sd",
+ "errorValue": 0.0
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
+ "errQualifier": "sem",
+ "errorValue": 0.043
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-031c747a-a865-3db8-8fbc-af72c00c6778.json b/src/enm/study-FCSV-031c747a-a865-3db8-8fbc-af72c00c6778.json
new file mode 100644
index 0000000..af69b32
--- /dev/null
+++ b/src/enm/study-FCSV-031c747a-a865-3db8-8fbc-af72c00c6778.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-031c747a-a865-3db8-8fbc-af72c00c6778",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6b15ab65-c2d3-3e58-ac04-18d8e1d45a7a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 3.282,
+ "errQualifier": "sd",
+ "errorValue": 1.024
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-0337b2d8-337c-3868-92e6-e1c3b2cd413b.json b/src/enm/study-FCSV-0337b2d8-337c-3868-92e6-e1c3b2cd413b.json
new file mode 100644
index 0000000..51c9dce
--- /dev/null
+++ b/src/enm/study-FCSV-0337b2d8-337c-3868-92e6-e1c3b2cd413b.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-0337b2d8-337c-3868-92e6-e1c3b2cd413b",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8b5b62c3-7fd2-3bba-b293-b7537e4971b1"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-03c1072d-7a21-3917-8c97-56beba0ec360.json b/src/enm/study-FCSV-03c1072d-7a21-3917-8c97-56beba0ec360.json
new file mode 100644
index 0000000..b14e37c
--- /dev/null
+++ b/src/enm/study-FCSV-03c1072d-7a21-3917-8c97-56beba0ec360.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-03c1072d-7a21-3917-8c97-56beba0ec360",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-7ad8c003-d0ee-3ea6-9374-b6e4d2f33401"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-04172a41-9fea-36d9-8b5c-cf0bd3577d21.json b/src/enm/study-FCSV-04172a41-9fea-36d9-8b5c-cf0bd3577d21.json
new file mode 100644
index 0000000..5c263b3
--- /dev/null
+++ b/src/enm/study-FCSV-04172a41-9fea-36d9-8b5c-cf0bd3577d21.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-04172a41-9fea-36d9-8b5c-cf0bd3577d21",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-b228fc7b-c407-368a-bc1c-359c7375bb9b"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-04386e9b-8b1f-3f64-9356-1947e3e22d87.json b/src/enm/study-FCSV-04386e9b-8b1f-3f64-9356-1947e3e22d87.json
new file mode 100644
index 0000000..fcb25ca
--- /dev/null
+++ b/src/enm/study-FCSV-04386e9b-8b1f-3f64-9356-1947e3e22d87.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-04386e9b-8b1f-3f64-9356-1947e3e22d87",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-924a51b9-97d3-31fb-b289-52688d9d0d3c"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Thiolated L-methionine"
+ }
+ }
+ ]
+}
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index 0000000..d98fd93
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index 0000000..b5ccd8c
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-079c4f57-edef-3197-b838-566877e5aa71.json b/src/enm/study-FCSV-079c4f57-edef-3197-b838-566877e5aa71.json
new file mode 100644
index 0000000..7fb751d
--- /dev/null
+++ b/src/enm/study-FCSV-079c4f57-edef-3197-b838-566877e5aa71.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-079c4f57-edef-3197-b838-566877e5aa71",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-f0cbcba3-1cb5-3fa5-82cc-bfd9d1afa21d"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.012,
+ "errQualifier": "sd",
+ "errorValue": 0.004
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
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+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-10341973-b4ae-325d-83b3-e0f2ccf4b1c6.json b/src/enm/study-FCSV-10341973-b4ae-325d-83b3-e0f2ccf4b1c6.json
new file mode 100644
index 0000000..2e5eec4
--- /dev/null
+++ b/src/enm/study-FCSV-10341973-b4ae-325d-83b3-e0f2ccf4b1c6.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-10341973-b4ae-325d-83b3-e0f2ccf4b1c6",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9b1b9ad6-e41d-3ddd-8bea-561af1fc27aa"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-10542832-b372-3663-967b-64ab6fd4f59e.json b/src/enm/study-FCSV-10542832-b372-3663-967b-64ab6fd4f59e.json
new file mode 100644
index 0000000..bd2fcf1
--- /dev/null
+++ b/src/enm/study-FCSV-10542832-b372-3663-967b-64ab6fd4f59e.json
@@ -0,0 +1,86 @@
+{
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
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+ },
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+ "doi: 10.1021/nn406018q"
+ ]
+ },
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+ }
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+ {
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+ "loQualifier": "mean",
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+}
diff --git a/src/enm/study-FCSV-107a45ba-60ed-321c-8604-e2018acbf0e9.json b/src/enm/study-FCSV-107a45ba-60ed-321c-8604-e2018acbf0e9.json
new file mode 100644
index 0000000..789bfa1
--- /dev/null
+++ b/src/enm/study-FCSV-107a45ba-60ed-321c-8604-e2018acbf0e9.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-107a45ba-60ed-321c-8604-e2018acbf0e9",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
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+ },
+ "protocol": {
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+ "category": {
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
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+ },
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+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
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+ "MEDIUM": " ",
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+ },
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+ {
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+}
diff --git a/src/enm/study-FCSV-108b37af-f1d9-33d1-a4c2-ffdb6c38aa40.json b/src/enm/study-FCSV-108b37af-f1d9-33d1-a4c2-ffdb6c38aa40.json
new file mode 100644
index 0000000..4f8f87c
--- /dev/null
+++ b/src/enm/study-FCSV-108b37af-f1d9-33d1-a4c2-ffdb6c38aa40.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-108b37af-f1d9-33d1-a4c2-ffdb6c38aa40",
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+ },
+ "protocol": {
+ "topcategory": "TOX",
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+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
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+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
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+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
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+ "effects": [
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+ "endpoint": "Spectral counts",
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+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-10ccff7a-7f93-3ccc-b288-b2ddf5cfed42.json b/src/enm/study-FCSV-10ccff7a-7f93-3ccc-b288-b2ddf5cfed42.json
new file mode 100644
index 0000000..5be04ca
--- /dev/null
+++ b/src/enm/study-FCSV-10ccff7a-7f93-3ccc-b288-b2ddf5cfed42.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-10ccff7a-7f93-3ccc-b288-b2ddf5cfed42",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9c9a7234-a74f-326f-a134-79e004c1f687"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Poly(vinyl alcohol)"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-10e0a115-5215-3a03-bf83-d2a76090c76e.json b/src/enm/study-FCSV-10e0a115-5215-3a03-bf83-d2a76090c76e.json
new file mode 100644
index 0000000..9bb9494
--- /dev/null
+++ b/src/enm/study-FCSV-10e0a115-5215-3a03-bf83-d2a76090c76e.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-10e0a115-5215-3a03-bf83-d2a76090c76e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8f5e6fcb-23b9-3222-aa6e-4afcbba47715"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
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+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 688.318,
+ "errQualifier": "sd",
+ "errorValue": 52.278
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 11,
+ "errQualifier": "sd",
+ "errorValue": 1
+ }
+ },
+ {
+ "endpoint": "Protein density",
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+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-10ecce98-5d9a-33f4-b0ff-52e746fc2d6e.json b/src/enm/study-FCSV-10ecce98-5d9a-33f4-b0ff-52e746fc2d6e.json
new file mode 100644
index 0000000..335b2a3
--- /dev/null
+++ b/src/enm/study-FCSV-10ecce98-5d9a-33f4-b0ff-52e746fc2d6e.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-10ecce98-5d9a-33f4-b0ff-52e746fc2d6e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9bf04ec0-f6b6-30a6-8970-19a51968532e"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.239,
+ "errQualifier": "sd",
+ "errorValue": 0.015
+ }
+ },
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.257,
+ "errQualifier": "sd",
+ "errorValue": 0.019
+ }
+ },
+ {
+ "endpoint": "LSPR peak position (nm)",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 539.73,
+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-11164ee9-05f6-3772-9352-aa6467832648.json b/src/enm/study-FCSV-11164ee9-05f6-3772-9352-aa6467832648.json
new file mode 100644
index 0000000..f05eb65
--- /dev/null
+++ b/src/enm/study-FCSV-11164ee9-05f6-3772-9352-aa6467832648.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-11164ee9-05f6-3772-9352-aa6467832648",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-acbbde2e-0238-3d4c-a2f4-7629ad478e6a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_studyResultType": "experimental result",
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-11212ddb-f743-3c93-b82e-10d6521e3d3d.json b/src/enm/study-FCSV-11212ddb-f743-3c93-b82e-10d6521e3d3d.json
new file mode 100644
index 0000000..d29717a
--- /dev/null
+++ b/src/enm/study-FCSV-11212ddb-f743-3c93-b82e-10d6521e3d3d.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-11212ddb-f743-3c93-b82e-10d6521e3d3d",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-2a853f39-424f-3a63-91f3-1300f85ebe73"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 23.15,
+ "errQualifier": "sd",
+ "errorValue": 0.87
+ }
+ },
+ {
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+ {
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+ }
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+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
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+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-130b1a65-fcd4-342c-b773-04e3683d01b1.json b/src/enm/study-FCSV-130b1a65-fcd4-342c-b773-04e3683d01b1.json
new file mode 100644
index 0000000..ec4f933
--- /dev/null
+++ b/src/enm/study-FCSV-130b1a65-fcd4-342c-b773-04e3683d01b1.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-130b1a65-fcd4-342c-b773-04e3683d01b1",
+ "owner": {
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+ "uuid": "FCSV-a7f3867d-85fc-33ab-8167-66b73c818f31"
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+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 1.909,
+ "errQualifier": "sd",
+ "errorValue": 0.313
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-130f5f5c-ef30-3af3-8603-f33b7f1df85e.json b/src/enm/study-FCSV-130f5f5c-ef30-3af3-8603-f33b7f1df85e.json
new file mode 100644
index 0000000..6a8aa29
--- /dev/null
+++ b/src/enm/study-FCSV-130f5f5c-ef30-3af3-8603-f33b7f1df85e.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-130f5f5c-ef30-3af3-8603-f33b7f1df85e",
+ "owner": {
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
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+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.005,
+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
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+ "Cell": "A549"
+ },
+ "result": {
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+ "loQualifier": "mean",
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+ }
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+ ]
+}
diff --git a/src/enm/study-FCSV-1336b809-d516-3fd2-8d57-b77762cb2667.json b/src/enm/study-FCSV-1336b809-d516-3fd2-8d57-b77762cb2667.json
new file mode 100644
index 0000000..51f3f06
--- /dev/null
+++ b/src/enm/study-FCSV-1336b809-d516-3fd2-8d57-b77762cb2667.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-1336b809-d516-3fd2-8d57-b77762cb2667",
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+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ }
+ },
+ {
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+}
diff --git a/src/enm/study-FCSV-13572856-5967-3cf0-91a5-5af5e5b841f5.json b/src/enm/study-FCSV-13572856-5967-3cf0-91a5-5af5e5b841f5.json
new file mode 100644
index 0000000..2d15b37
--- /dev/null
+++ b/src/enm/study-FCSV-13572856-5967-3cf0-91a5-5af5e5b841f5.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-13572856-5967-3cf0-91a5-5af5e5b841f5",
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+ }
+ },
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
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+ },
+ "effects": [
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+ "endpoint": "Spectral counts",
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+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-138df243-dfd0-3bca-873c-14c9ebd8698f.json b/src/enm/study-FCSV-138df243-dfd0-3bca-873c-14c9ebd8698f.json
new file mode 100644
index 0000000..0758482
--- /dev/null
+++ b/src/enm/study-FCSV-138df243-dfd0-3bca-873c-14c9ebd8698f.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-138df243-dfd0-3bca-873c-14c9ebd8698f",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6405ef25-683e-3763-a4e3-f56eb93174e4"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.299,
+ "errQualifier": "sd",
+ "errorValue": 0.005
+ }
+ },
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-148ac9e1-6cdb-38e9-930e-2e29213cb447.json b/src/enm/study-FCSV-148ac9e1-6cdb-38e9-930e-2e29213cb447.json
new file mode 100644
index 0000000..317e2ec
--- /dev/null
+++ b/src/enm/study-FCSV-148ac9e1-6cdb-38e9-930e-2e29213cb447.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-148ac9e1-6cdb-38e9-930e-2e29213cb447",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-2de5071e-596b-3507-84fc-f9ba470cbcbf"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-148d13fb-53d7-3da9-9d01-23aff8a9f457.json b/src/enm/study-FCSV-148d13fb-53d7-3da9-9d01-23aff8a9f457.json
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index 0000000..abc9965
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+++ b/src/enm/study-FCSV-148d13fb-53d7-3da9-9d01-23aff8a9f457.json
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+{
+ "uuid": "FCSV-148d13fb-53d7-3da9-9d01-23aff8a9f457",
+ "owner": {
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
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+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
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+ },
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+ },
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+ }
+ },
+ {
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+ },
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+ {
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+ {
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+ },
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diff --git a/src/enm/study-FCSV-150c15f1-0968-37d7-a389-5ef5052edfb1.json b/src/enm/study-FCSV-150c15f1-0968-37d7-a389-5ef5052edfb1.json
new file mode 100644
index 0000000..ab71b32
--- /dev/null
+++ b/src/enm/study-FCSV-150c15f1-0968-37d7-a389-5ef5052edfb1.json
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+{
+ "uuid": "FCSV-150c15f1-0968-37d7-a389-5ef5052edfb1",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
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+ }
+ },
+ {
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+ "MEDIUM": "Human serum (Sigma #H4522)",
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+ },
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+}
diff --git a/src/enm/study-FCSV-151757f1-9270-3757-a224-2a2469f1478a.json b/src/enm/study-FCSV-151757f1-9270-3757-a224-2a2469f1478a.json
new file mode 100644
index 0000000..46a9249
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+++ b/src/enm/study-FCSV-151757f1-9270-3757-a224-2a2469f1478a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-151757f1-9270-3757-a224-2a2469f1478a",
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+ "company": {
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+ },
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
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+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-153bdca6-e55e-3da8-a28d-0c9d3ec85dc8.json b/src/enm/study-FCSV-153bdca6-e55e-3da8-a28d-0c9d3ec85dc8.json
new file mode 100644
index 0000000..3c30c83
--- /dev/null
+++ b/src/enm/study-FCSV-153bdca6-e55e-3da8-a28d-0c9d3ec85dc8.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-153bdca6-e55e-3da8-a28d-0c9d3ec85dc8",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-5b29295c-f2ab-3e5a-bb32-37caac38b002"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Thiolated L-asparagine"
+ }
+ }
+ ]
+}
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+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-18606315-8e61-3976-b801-7805429d99ad.json b/src/enm/study-FCSV-18606315-8e61-3976-b801-7805429d99ad.json
new file mode 100644
index 0000000..8167c6c
--- /dev/null
+++ b/src/enm/study-FCSV-18606315-8e61-3976-b801-7805429d99ad.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-18606315-8e61-3976-b801-7805429d99ad",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-924a51b9-97d3-31fb-b289-52688d9d0d3c"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 260.336,
+ "errQualifier": "sd",
+ "errorValue": 4.165
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-1bf73c22-010c-3d73-a7a5-8b3213b9e244.json b/src/enm/study-FCSV-1bf73c22-010c-3d73-a7a5-8b3213b9e244.json
new file mode 100644
index 0000000..82b68de
--- /dev/null
+++ b/src/enm/study-FCSV-1bf73c22-010c-3d73-a7a5-8b3213b9e244.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-1bf73c22-010c-3d73-a7a5-8b3213b9e244",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-5c14595c-0e23-3f37-aaad-9988eba09196"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 22.36,
+ "errQualifier": "sd",
+ "errorValue": 0.46
+ }
+ },
+ {
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index 0000000..49c83a0
--- /dev/null
+++ b/src/enm/study-FCSV-1cd7fcc4-dec1-36e3-b78d-e0f62d328081.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-1cd7fcc4-dec1-36e3-b78d-e0f62d328081",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-bc77c03d-4e75-3fab-bb3d-17b983663819"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-1ceadd7c-e301-3529-9130-7a4b9df74aed.json b/src/enm/study-FCSV-1ceadd7c-e301-3529-9130-7a4b9df74aed.json
new file mode 100644
index 0000000..5d83c28
--- /dev/null
+++ b/src/enm/study-FCSV-1ceadd7c-e301-3529-9130-7a4b9df74aed.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-1ceadd7c-e301-3529-9130-7a4b9df74aed",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-62d68a47-f27e-3d76-a7cf-5cacae221ec7"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Ag]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-1d233288-dc06-3c40-9b33-7b915935eb8e.json b/src/enm/study-FCSV-1d233288-dc06-3c40-9b33-7b915935eb8e.json
new file mode 100644
index 0000000..5978da3
--- /dev/null
+++ b/src/enm/study-FCSV-1d233288-dc06-3c40-9b33-7b915935eb8e.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-1d233288-dc06-3c40-9b33-7b915935eb8e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9294730f-3d55-36da-80b9-eb2df162e805"
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+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
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+ "r_isUsedforClassification": "false",
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+ },
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+ },
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
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+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Octadecylamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-1d5622db-e628-386c-a854-3b8e9b231282.json b/src/enm/study-FCSV-1d5622db-e628-386c-a854-3b8e9b231282.json
new file mode 100644
index 0000000..39bd2a7
--- /dev/null
+++ b/src/enm/study-FCSV-1d5622db-e628-386c-a854-3b8e9b231282.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-1d5622db-e628-386c-a854-3b8e9b231282",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
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+ },
+ "reliability": {
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+ },
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+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 31.6,
+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "Density",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/cm^3",
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+ "loValue": 19.1
+ }
+ },
+ {
+ "endpoint": "MW",
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+ },
+ "result": {
+ "unit": "g/mol",
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+ "loValue": 197
+ }
+ },
+ {
+ "endpoint": "Mol/NP",
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+ "PHRASEOTHER_PERCENTILE": null,
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+ },
+ "result": {
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+ {
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+ },
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+ "loValue": 0.0
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+}
diff --git a/src/enm/study-FCSV-1d976109-c237-3eda-9b62-34d34abb6d00.json b/src/enm/study-FCSV-1d976109-c237-3eda-9b62-34d34abb6d00.json
new file mode 100644
index 0000000..9879bd7
--- /dev/null
+++ b/src/enm/study-FCSV-1d976109-c237-3eda-9b62-34d34abb6d00.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-1d976109-c237-3eda-9b62-34d34abb6d00",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9b1b9ad6-e41d-3ddd-8bea-561af1fc27aa"
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+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
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+ },
+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-1df7bae9-3da0-32ec-a2b0-e3161d7cd124.json b/src/enm/study-FCSV-1df7bae9-3da0-32ec-a2b0-e3161d7cd124.json
new file mode 100644
index 0000000..a361667
--- /dev/null
+++ b/src/enm/study-FCSV-1df7bae9-3da0-32ec-a2b0-e3161d7cd124.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-1df7bae9-3da0-32ec-a2b0-e3161d7cd124",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-98074b22-064e-3cd7-a732-f5fa3005fa73"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": 25.73,
+ "errQualifier": "sd",
+ "errorValue": 2.08
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
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new file mode 100644
index 0000000..e16e4b5
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index 0000000..8e12ece
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index 0000000..e80f17f
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index 0000000..6a5beae
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new file mode 100644
index 0000000..3a9e4df
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new file mode 100644
index 0000000..5dfb9a6
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diff --git a/src/enm/study-FCSV-1f844a64-a184-3f67-9656-d91bb4e97100.json b/src/enm/study-FCSV-1f844a64-a184-3f67-9656-d91bb4e97100.json
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+{
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diff --git a/src/enm/study-FCSV-2056b6d4-b2b6-33dd-85bd-1b778c1e9f22.json b/src/enm/study-FCSV-2056b6d4-b2b6-33dd-85bd-1b778c1e9f22.json
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index 0000000..e7e9360
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+++ b/src/enm/study-FCSV-2056b6d4-b2b6-33dd-85bd-1b778c1e9f22.json
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+{
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+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
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new file mode 100644
index 0000000..33398fe
--- /dev/null
+++ b/src/enm/study-FCSV-20791a10-de3a-33d5-b693-f330cf6986aa.json
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-207fbb9d-8d7a-31a7-adbb-944d53e0a329.json b/src/enm/study-FCSV-207fbb9d-8d7a-31a7-adbb-944d53e0a329.json
new file mode 100644
index 0000000..5599694
--- /dev/null
+++ b/src/enm/study-FCSV-207fbb9d-8d7a-31a7-adbb-944d53e0a329.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-207fbb9d-8d7a-31a7-adbb-944d53e0a329",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9505d90b-f90b-3c94-a6cc-e4ee4c8ec46f"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 27.94,
+ "errQualifier": "sd",
+ "errorValue": 2.96
+ }
+ },
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "1-Dodecanethiol"
+ }
+ },
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "sodium dodecyl sulfate"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2288fe58-1573-3efd-81b9-2539c475d1ae.json b/src/enm/study-FCSV-2288fe58-1573-3efd-81b9-2539c475d1ae.json
new file mode 100644
index 0000000..ed5b7a0
--- /dev/null
+++ b/src/enm/study-FCSV-2288fe58-1573-3efd-81b9-2539c475d1ae.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-2288fe58-1573-3efd-81b9-2539c475d1ae",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-cd7105f2-f630-360e-b8dc-ff42b18bb421"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-22b70a1b-f42c-3516-9104-c6514dea801d.json b/src/enm/study-FCSV-22b70a1b-f42c-3516-9104-c6514dea801d.json
new file mode 100644
index 0000000..db85a46
--- /dev/null
+++ b/src/enm/study-FCSV-22b70a1b-f42c-3516-9104-c6514dea801d.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-22b70a1b-f42c-3516-9104-c6514dea801d",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-43f0ea59-aa2f-31d8-8d87-19c95ec9be18"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-22bbb494-8e7c-3e71-8521-fa4835374e6e.json b/src/enm/study-FCSV-22bbb494-8e7c-3e71-8521-fa4835374e6e.json
new file mode 100644
index 0000000..5c7500d
--- /dev/null
+++ b/src/enm/study-FCSV-22bbb494-8e7c-3e71-8521-fa4835374e6e.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-22bbb494-8e7c-3e71-8521-fa4835374e6e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-a153cba3-a82d-3e3c-bcbd-335cc5155f44"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-22cc554a-1080-3f99-9ef2-82cda96423bb.json b/src/enm/study-FCSV-22cc554a-1080-3f99-9ef2-82cda96423bb.json
new file mode 100644
index 0000000..fdb4f7d
--- /dev/null
+++ b/src/enm/study-FCSV-22cc554a-1080-3f99-9ef2-82cda96423bb.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-22cc554a-1080-3f99-9ef2-82cda96423bb",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6405ef25-683e-3763-a4e3-f56eb93174e4"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 14.9,
+ "errQualifier": "sd",
+ "errorValue": 1.2
+ }
+ },
+ {
+ "endpoint": "Density",
+ "conditions": {
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+ },
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+ {
+ "endpoint": "SA/NP",
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+ "PHRASEOTHER_PERCENTILE": null,
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+}
diff --git a/src/enm/study-FCSV-2329b1e2-5625-3256-ab0a-1e28f86911c6.json b/src/enm/study-FCSV-2329b1e2-5625-3256-ab0a-1e28f86911c6.json
new file mode 100644
index 0000000..370ddc2
--- /dev/null
+++ b/src/enm/study-FCSV-2329b1e2-5625-3256-ab0a-1e28f86911c6.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-2329b1e2-5625-3256-ab0a-1e28f86911c6",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-45779e93-a25d-39cc-9294-afc0b59f3cd6"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -6.33,
+ "errQualifier": "sd",
+ "errorValue": 5.81
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -5.91,
+ "errQualifier": "sd",
+ "errorValue": 1.52
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2340ebf4-ff01-3604-8565-f271d1b4423b.json b/src/enm/study-FCSV-2340ebf4-ff01-3604-8565-f271d1b4423b.json
new file mode 100644
index 0000000..0f1a627
--- /dev/null
+++ b/src/enm/study-FCSV-2340ebf4-ff01-3604-8565-f271d1b4423b.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-2340ebf4-ff01-3604-8565-f271d1b4423b",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-45779e93-a25d-39cc-9294-afc0b59f3cd6"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-23483f83-4970-311e-b5ec-6b6fbc2ecf99.json b/src/enm/study-FCSV-23483f83-4970-311e-b5ec-6b6fbc2ecf99.json
new file mode 100644
index 0000000..d566a5f
--- /dev/null
+++ b/src/enm/study-FCSV-23483f83-4970-311e-b5ec-6b6fbc2ecf99.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-23483f83-4970-311e-b5ec-6b6fbc2ecf99",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9b1b9ad6-e41d-3ddd-8bea-561af1fc27aa"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.215,
+ "errQualifier": "sd",
+ "errorValue": 0.018
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
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+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -13.98,
+ "errQualifier": "sd",
+ "errorValue": 8.89
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -8.6,
+ "errQualifier": "sd",
+ "errorValue": 2.25
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-252b6b2f-8cdd-303d-8a9f-19afae8bea9f.json b/src/enm/study-FCSV-252b6b2f-8cdd-303d-8a9f-19afae8bea9f.json
new file mode 100644
index 0000000..fb5c543
--- /dev/null
+++ b/src/enm/study-FCSV-252b6b2f-8cdd-303d-8a9f-19afae8bea9f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-252b6b2f-8cdd-303d-8a9f-19afae8bea9f",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-e4b9ce55-bbeb-368b-a1d4-e591b7df742e"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-25898b79-92f7-3833-83c3-8093f1ff42d2.json b/src/enm/study-FCSV-25898b79-92f7-3833-83c3-8093f1ff42d2.json
new file mode 100644
index 0000000..01854b3
--- /dev/null
+++ b/src/enm/study-FCSV-25898b79-92f7-3833-83c3-8093f1ff42d2.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-25898b79-92f7-3833-83c3-8093f1ff42d2",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-bc488cf3-986d-34cf-9ee7-12f98873dfe4"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.092,
+ "errQualifier": "sd",
+ "errorValue": 0.117
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
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+ ]
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diff --git a/src/enm/study-FCSV-263b03c8-1ce3-3310-a03b-2188c46d920b.json b/src/enm/study-FCSV-263b03c8-1ce3-3310-a03b-2188c46d920b.json
new file mode 100644
index 0000000..02cbf1c
--- /dev/null
+++ b/src/enm/study-FCSV-263b03c8-1ce3-3310-a03b-2188c46d920b.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-263b03c8-1ce3-3310-a03b-2188c46d920b",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-3c5fb4b0-2e4e-3dae-9eb2-1dbfd202cd13"
+ },
+ "company": {
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Bis(p-sulfonatophenyl)phenylphosphine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-266e466b-3943-36db-b23f-4323481f319d.json b/src/enm/study-FCSV-266e466b-3943-36db-b23f-4323481f319d.json
new file mode 100644
index 0000000..70c7249
--- /dev/null
+++ b/src/enm/study-FCSV-266e466b-3943-36db-b23f-4323481f319d.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-266e466b-3943-36db-b23f-4323481f319d",
+ "owner": {
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+ "uuid": "FCSV-9cc7dd73-d27f-35a0-a3f1-81a18429b76a"
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
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+ "Description"
+ ]
+ },
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+ },
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+ "r_studyResultType": "experimental result",
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+ },
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+ },
+ "effects": [
+ {
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-26bb43bf-11d3-3ced-aff5-d6d4184c6adb.json b/src/enm/study-FCSV-26bb43bf-11d3-3ced-aff5-d6d4184c6adb.json
new file mode 100644
index 0000000..95cfbe3
--- /dev/null
+++ b/src/enm/study-FCSV-26bb43bf-11d3-3ced-aff5-d6d4184c6adb.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-26bb43bf-11d3-3ced-aff5-d6d4184c6adb",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9043e884-a5ba-3fa6-a103-dee0c7b1b3dd"
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
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+ },
+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-26c42f29-a869-3e3b-b312-eadf162532a0.json b/src/enm/study-FCSV-26c42f29-a869-3e3b-b312-eadf162532a0.json
new file mode 100644
index 0000000..494112c
--- /dev/null
+++ b/src/enm/study-FCSV-26c42f29-a869-3e3b-b312-eadf162532a0.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-26c42f29-a869-3e3b-b312-eadf162532a0",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-98074b22-064e-3cd7-a732-f5fa3005fa73"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 844.364,
+ "errQualifier": "sd",
+ "errorValue": 126.091
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 9,
+ "errQualifier": "sd",
+ "errorValue": 1
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
+ "errQualifier": "sem",
+ "errorValue": 0.012
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-27e732d9-9489-3120-a0c6-5f4c87602375.json b/src/enm/study-FCSV-27e732d9-9489-3120-a0c6-5f4c87602375.json
new file mode 100644
index 0000000..585b1c2
--- /dev/null
+++ b/src/enm/study-FCSV-27e732d9-9489-3120-a0c6-5f4c87602375.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-27e732d9-9489-3120-a0c6-5f4c87602375",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-f3d54c07-7dd4-3124-b5bf-341eb9eb4e82"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 23.8,
+ "errQualifier": "sd",
+ "errorValue": 0.56
+ }
+ },
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 55.98,
+ "errQualifier": "sd",
+ "errorValue": 3.74
+ }
+ },
+ {
+ "endpoint": "Volume Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 4.11,
+ "errQualifier": "sd",
+ "errorValue": 5.12
+ }
+ },
+ {
+ "endpoint": "Volume Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 221.93,
+ "errQualifier": "sd",
+ "errorValue": 331.85
+ }
+ },
+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 29.49,
+ "errQualifier": "sd",
+ "errorValue": 4.71
+ }
+ },
+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 25.25,
+ "errQualifier": "sd",
+ "errorValue": 15.43
+ }
+ },
+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 29.49,
+ "errQualifier": "sd",
+ "errorValue": 1.91
+ }
+ },
+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 83.34,
+ "errQualifier": "sd",
+ "errorValue": 26.11
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2852a2e8-953c-3ad5-9fde-a71dfe4a8aa5.json b/src/enm/study-FCSV-2852a2e8-953c-3ad5-9fde-a71dfe4a8aa5.json
new file mode 100644
index 0000000..c34929d
--- /dev/null
+++ b/src/enm/study-FCSV-2852a2e8-953c-3ad5-9fde-a71dfe4a8aa5.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-2852a2e8-953c-3ad5-9fde-a71dfe4a8aa5",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-1a71d2b3-8121-3790-a66b-774b12829bb3"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2877a6cf-39c2-38bb-9ad3-af3b4e74d4ba.json b/src/enm/study-FCSV-2877a6cf-39c2-38bb-9ad3-af3b4e74d4ba.json
new file mode 100644
index 0000000..7ff4643
--- /dev/null
+++ b/src/enm/study-FCSV-2877a6cf-39c2-38bb-9ad3-af3b4e74d4ba.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-2877a6cf-39c2-38bb-9ad3-af3b4e74d4ba",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8f5e6fcb-23b9-3222-aa6e-4afcbba47715"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Thiolated poly(L-lysine)"
+ }
+ }
+ ]
+}
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index 0000000..82df9f3
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new file mode 100644
index 0000000..a713801
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+{
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index 0000000..ea8cd25
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+{
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index 0000000..1571ab1
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diff --git a/src/enm/study-FCSV-2c55fc4a-ed47-3fa3-8594-c6839e0ca647.json b/src/enm/study-FCSV-2c55fc4a-ed47-3fa3-8594-c6839e0ca647.json
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index 0000000..caa8570
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+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2dea8469-3f5a-35a1-9028-ee3f873242f6.json b/src/enm/study-FCSV-2dea8469-3f5a-35a1-9028-ee3f873242f6.json
new file mode 100644
index 0000000..3e33518
--- /dev/null
+++ b/src/enm/study-FCSV-2dea8469-3f5a-35a1-9028-ee3f873242f6.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-2dea8469-3f5a-35a1-9028-ee3f873242f6",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-4026a85b-f254-3d35-bd77-c634d38e4a22"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2e0bbe94-3e94-3d10-9a2f-f89aba471c76.json b/src/enm/study-FCSV-2e0bbe94-3e94-3d10-9a2f-f89aba471c76.json
new file mode 100644
index 0000000..6fedd1f
--- /dev/null
+++ b/src/enm/study-FCSV-2e0bbe94-3e94-3d10-9a2f-f89aba471c76.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-2e0bbe94-3e94-3d10-9a2f-f89aba471c76",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-770a2d39-1509-3c93-b28f-1d3e345de450"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.004,
+ "errQualifier": "sd",
+ "errorValue": 0.006
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": -8.116,
+ "errQualifier": "std",
+ "errorValue": 2.417
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2e11655c-d54d-317f-8c2d-6e3b8c7a7304.json b/src/enm/study-FCSV-2e11655c-d54d-317f-8c2d-6e3b8c7a7304.json
new file mode 100644
index 0000000..d9d9709
--- /dev/null
+++ b/src/enm/study-FCSV-2e11655c-d54d-317f-8c2d-6e3b8c7a7304.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-2e11655c-d54d-317f-8c2d-6e3b8c7a7304",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-80a36fc5-9a73-358c-829b-2e69eea82125"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2e652225-6953-30bf-bfc0-fd1562f1e5c5.json b/src/enm/study-FCSV-2e652225-6953-30bf-bfc0-fd1562f1e5c5.json
new file mode 100644
index 0000000..7575a5c
--- /dev/null
+++ b/src/enm/study-FCSV-2e652225-6953-30bf-bfc0-fd1562f1e5c5.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-2e652225-6953-30bf-bfc0-fd1562f1e5c5",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8f5cd32a-3350-300b-91d0-87000ee5d7ee"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 4.602,
+ "errQualifier": "sd",
+ "errorValue": 0.665
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2eb4073a-afc7-37ac-a361-ea02e938471e.json b/src/enm/study-FCSV-2eb4073a-afc7-37ac-a361-ea02e938471e.json
new file mode 100644
index 0000000..cfc9f2b
--- /dev/null
+++ b/src/enm/study-FCSV-2eb4073a-afc7-37ac-a361-ea02e938471e.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-2eb4073a-afc7-37ac-a361-ea02e938471e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-f3d54c07-7dd4-3124-b5bf-341eb9eb4e82"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2eb7f4fc-980e-39a7-ad81-137da4447a2d.json b/src/enm/study-FCSV-2eb7f4fc-980e-39a7-ad81-137da4447a2d.json
new file mode 100644
index 0000000..7dab122
--- /dev/null
+++ b/src/enm/study-FCSV-2eb7f4fc-980e-39a7-ad81-137da4447a2d.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-2eb7f4fc-980e-39a7-ad81-137da4447a2d",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-eec391e5-065c-32c1-89ca-3eb40260c1a8"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "11-Amino-1-undecanethiol"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2edccfb9-db9c-371b-a748-f5e1de3bee65.json b/src/enm/study-FCSV-2edccfb9-db9c-371b-a748-f5e1de3bee65.json
new file mode 100644
index 0000000..92b9696
--- /dev/null
+++ b/src/enm/study-FCSV-2edccfb9-db9c-371b-a748-f5e1de3bee65.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-2edccfb9-db9c-371b-a748-f5e1de3bee65",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-2a853f39-424f-3a63-91f3-1300f85ebe73"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2ef9a412-3108-3e48-9e60-8574204ab4f7.json b/src/enm/study-FCSV-2ef9a412-3108-3e48-9e60-8574204ab4f7.json
new file mode 100644
index 0000000..ed2da5e
--- /dev/null
+++ b/src/enm/study-FCSV-2ef9a412-3108-3e48-9e60-8574204ab4f7.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-2ef9a412-3108-3e48-9e60-8574204ab4f7",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-bc77c03d-4e75-3fab-bb3d-17b983663819"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.084,
+ "errQualifier": "sd",
+ "errorValue": 0.035
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
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diff --git a/src/enm/study-FCSV-2f0e67fc-7638-3e12-9ad2-c7bda0b48723.json b/src/enm/study-FCSV-2f0e67fc-7638-3e12-9ad2-c7bda0b48723.json
new file mode 100644
index 0000000..11ac99a
--- /dev/null
+++ b/src/enm/study-FCSV-2f0e67fc-7638-3e12-9ad2-c7bda0b48723.json
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+{
+ "uuid": "FCSV-2f0e67fc-7638-3e12-9ad2-c7bda0b48723",
+ "owner": {
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
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+ },
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+ },
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+ "loValue": 19.1
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+ {
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+ },
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diff --git a/src/enm/study-FCSV-2f136a7d-6d7b-3ad9-9a7d-725611579a1c.json b/src/enm/study-FCSV-2f136a7d-6d7b-3ad9-9a7d-725611579a1c.json
new file mode 100644
index 0000000..8916ad4
--- /dev/null
+++ b/src/enm/study-FCSV-2f136a7d-6d7b-3ad9-9a7d-725611579a1c.json
@@ -0,0 +1,73 @@
+{
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+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
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+ },
+ "reliability": {
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+ {
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+ "MEDIUM": "Human serum (Sigma #H4522)"
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+}
diff --git a/src/enm/study-FCSV-2f8cb6f0-a503-3640-b9b9-e29edb3703ed.json b/src/enm/study-FCSV-2f8cb6f0-a503-3640-b9b9-e29edb3703ed.json
new file mode 100644
index 0000000..fa3c816
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+++ b/src/enm/study-FCSV-2f8cb6f0-a503-3640-b9b9-e29edb3703ed.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-2f8cb6f0-a503-3640-b9b9-e29edb3703ed",
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-2fa8ff94-819e-3457-8b60-5e7d705091be.json b/src/enm/study-FCSV-2fa8ff94-819e-3457-8b60-5e7d705091be.json
new file mode 100644
index 0000000..93d548a
--- /dev/null
+++ b/src/enm/study-FCSV-2fa8ff94-819e-3457-8b60-5e7d705091be.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-2fa8ff94-819e-3457-8b60-5e7d705091be",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6b15ab65-c2d3-3e58-ac04-18d8e1d45a7a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 22.16,
+ "errQualifier": "sd",
+ "errorValue": 1.4
+ }
+ },
+ {
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+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 192.686,
+ "errQualifier": "sd",
+ "errorValue": 98.103
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 8,
+ "errQualifier": "sd",
+ "errorValue": 4
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
+ "errQualifier": "sem",
+ "errorValue": 0.037
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-3129c5f7-16ff-3a56-be4b-c7716c529b8a.json b/src/enm/study-FCSV-3129c5f7-16ff-3a56-be4b-c7716c529b8a.json
new file mode 100644
index 0000000..57fed93
--- /dev/null
+++ b/src/enm/study-FCSV-3129c5f7-16ff-3a56-be4b-c7716c529b8a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-3129c5f7-16ff-3a56-be4b-c7716c529b8a",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-130b04ab-86e6-38d6-9276-e2db1b4dcffb"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-31328940-3cd8-375f-b624-379758b9034e.json b/src/enm/study-FCSV-31328940-3cd8-375f-b624-379758b9034e.json
new file mode 100644
index 0000000..0ec7ed9
--- /dev/null
+++ b/src/enm/study-FCSV-31328940-3cd8-375f-b624-379758b9034e.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-31328940-3cd8-375f-b624-379758b9034e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-4683cde2-ec2e-3a2e-974a-3ba15cd79d05"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Stearic acid"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-3140ce3a-2d98-3024-b606-c98d22e2d492.json b/src/enm/study-FCSV-3140ce3a-2d98-3024-b606-c98d22e2d492.json
new file mode 100644
index 0000000..990b1b3
--- /dev/null
+++ b/src/enm/study-FCSV-3140ce3a-2d98-3024-b606-c98d22e2d492.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-3140ce3a-2d98-3024-b606-c98d22e2d492",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-c4e9df58-f3fb-34f6-9c56-0626c12fb1b7"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 0.286,
+ "errQualifier": "sd",
+ "errorValue": 0.241
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-3147052d-43f3-309c-b1e6-cf680f0e3445.json b/src/enm/study-FCSV-3147052d-43f3-309c-b1e6-cf680f0e3445.json
new file mode 100644
index 0000000..68cac78
--- /dev/null
+++ b/src/enm/study-FCSV-3147052d-43f3-309c-b1e6-cf680f0e3445.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-3147052d-43f3-309c-b1e6-cf680f0e3445",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-b38f2b71-aa2d-3d72-af88-166a60bedee2"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-31653c7e-9974-387d-8a3f-5629a8d8370f.json b/src/enm/study-FCSV-31653c7e-9974-387d-8a3f-5629a8d8370f.json
new file mode 100644
index 0000000..dd157a1
--- /dev/null
+++ b/src/enm/study-FCSV-31653c7e-9974-387d-8a3f-5629a8d8370f.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-31653c7e-9974-387d-8a3f-5629a8d8370f",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-50aee86c-a3a2-3c46-86bf-5ac25485fc13"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.164,
+ "errQualifier": "sd",
+ "errorValue": 0.003
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-337595e5-fd70-3200-8c5b-c4698830f585.json b/src/enm/study-FCSV-337595e5-fd70-3200-8c5b-c4698830f585.json
new file mode 100644
index 0000000..a74fa20
--- /dev/null
+++ b/src/enm/study-FCSV-337595e5-fd70-3200-8c5b-c4698830f585.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-337595e5-fd70-3200-8c5b-c4698830f585",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-770a2d39-1509-3c93-b28f-1d3e345de450"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.122,
+ "errQualifier": "sd",
+ "errorValue": 0.018
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
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+ "loQualifier": "mean",
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+ "errorValue": 0.56
+ }
+ },
+ {
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+ "PHRASEOTHER_PERCENTILE": null,
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+ "SEQ_NUM": null
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "Volume Mean Hydrodynamic Diameter",
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
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+ "loValue": 39.59,
+ "errQualifier": "sd",
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+ }
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+ {
+ "endpoint": "Volume Mean Hydrodynamic Diameter",
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+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
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+ "loValue": 44.04,
+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
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+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
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+ },
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+ }
+ },
+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
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+ "loValue": 69.55,
+ "errQualifier": "sd",
+ "errorValue": 2.07
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-34be1e93-4ad6-30c7-b131-83effb3ddc60.json b/src/enm/study-FCSV-34be1e93-4ad6-30c7-b131-83effb3ddc60.json
new file mode 100644
index 0000000..c6d011e
--- /dev/null
+++ b/src/enm/study-FCSV-34be1e93-4ad6-30c7-b131-83effb3ddc60.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-34be1e93-4ad6-30c7-b131-83effb3ddc60",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-fb5e6048-8ee1-351d-915b-d1669681357e"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-34be497f-8cdb-36bd-b3e5-3d6d3b4f487a.json b/src/enm/study-FCSV-34be497f-8cdb-36bd-b3e5-3d6d3b4f487a.json
new file mode 100644
index 0000000..43b28bf
--- /dev/null
+++ b/src/enm/study-FCSV-34be497f-8cdb-36bd-b3e5-3d6d3b4f487a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-34be497f-8cdb-36bd-b3e5-3d6d3b4f487a",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6d8b8701-7fca-3936-a45e-66c17012fc75"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-34e85b56-f082-3918-9a82-dfdd2325dd2c.json b/src/enm/study-FCSV-34e85b56-f082-3918-9a82-dfdd2325dd2c.json
new file mode 100644
index 0000000..4782a6c
--- /dev/null
+++ b/src/enm/study-FCSV-34e85b56-f082-3918-9a82-dfdd2325dd2c.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-34e85b56-f082-3918-9a82-dfdd2325dd2c",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8e1a76df-a12d-3254-ae6b-28e20153ef59"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 83.89,
+ "errQualifier": "sd",
+ "errorValue": 6.01
+ }
+ },
+ {
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+ "result": {
+ "unit": "nm",
+ "loValue": 52.3,
+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
+ "conditions": {
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
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+ }
+ },
+ {
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
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+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 58.19,
+ "errQualifier": "sd",
+ "errorValue": 4.53
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-39d8afd3-6fe2-3e44-b332-fa35013716d4.json b/src/enm/study-FCSV-39d8afd3-6fe2-3e44-b332-fa35013716d4.json
new file mode 100644
index 0000000..03251d1
--- /dev/null
+++ b/src/enm/study-FCSV-39d8afd3-6fe2-3e44-b332-fa35013716d4.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-39d8afd3-6fe2-3e44-b332-fa35013716d4",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-2de5071e-596b-3507-84fc-f9ba470cbcbf"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.228,
+ "errQualifier": "sd",
+ "errorValue": 0.07
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.201,
+ "errQualifier": "sd",
+ "errorValue": 0.061
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-39eec7d6-9810-3d05-8d96-d7cf3af1b5f4.json b/src/enm/study-FCSV-39eec7d6-9810-3d05-8d96-d7cf3af1b5f4.json
new file mode 100644
index 0000000..6318a04
--- /dev/null
+++ b/src/enm/study-FCSV-39eec7d6-9810-3d05-8d96-d7cf3af1b5f4.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-39eec7d6-9810-3d05-8d96-d7cf3af1b5f4",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-06c1d24b-426b-39ec-8047-700808302325"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-3a119664-52ae-3fbf-b899-ffadb2403017.json b/src/enm/study-FCSV-3a119664-52ae-3fbf-b899-ffadb2403017.json
new file mode 100644
index 0000000..cd598e3
--- /dev/null
+++ b/src/enm/study-FCSV-3a119664-52ae-3fbf-b899-ffadb2403017.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-3a119664-52ae-3fbf-b899-ffadb2403017",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-5c14595c-0e23-3f37-aaad-9988eba09196"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 261.016,
+ "errQualifier": "sd",
+ "errorValue": 2.358
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-3bf2ad76-d70f-357b-bf05-3d4599247789.json b/src/enm/study-FCSV-3bf2ad76-d70f-357b-bf05-3d4599247789.json
new file mode 100644
index 0000000..14e0673
--- /dev/null
+++ b/src/enm/study-FCSV-3bf2ad76-d70f-357b-bf05-3d4599247789.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-3bf2ad76-d70f-357b-bf05-3d4599247789",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-f3d54c07-7dd4-3124-b5bf-341eb9eb4e82"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.326,
+ "errQualifier": "sd",
+ "errorValue": 0.019
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
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+{
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+{
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index 0000000..7448db5
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index 0000000..8a7df1b
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-3e90f4c3-45be-33f3-8879-cabf7f29498f.json b/src/enm/study-FCSV-3e90f4c3-45be-33f3-8879-cabf7f29498f.json
new file mode 100644
index 0000000..0187a5c
--- /dev/null
+++ b/src/enm/study-FCSV-3e90f4c3-45be-33f3-8879-cabf7f29498f.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-3e90f4c3-45be-33f3-8879-cabf7f29498f",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-d1731b11-29a7-3b39-bf48-000a31d9c46b"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
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+ ]
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+}
diff --git a/src/enm/study-FCSV-3fda0195-c559-39be-a256-55cab9a4b888.json b/src/enm/study-FCSV-3fda0195-c559-39be-a256-55cab9a4b888.json
new file mode 100644
index 0000000..93593d9
--- /dev/null
+++ b/src/enm/study-FCSV-3fda0195-c559-39be-a256-55cab9a4b888.json
@@ -0,0 +1,77 @@
+{
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
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+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
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+ },
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+ {
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+}
diff --git a/src/enm/study-FCSV-3fe257ad-d8bb-3e54-b6c2-767cb5d79b77.json b/src/enm/study-FCSV-3fe257ad-d8bb-3e54-b6c2-767cb5d79b77.json
new file mode 100644
index 0000000..c6b4a06
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+++ b/src/enm/study-FCSV-3fe257ad-d8bb-3e54-b6c2-767cb5d79b77.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-3fe257ad-d8bb-3e54-b6c2-767cb5d79b77",
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+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-3fe25d8f-147e-359a-8587-0131e11ba51e.json b/src/enm/study-FCSV-3fe25d8f-147e-359a-8587-0131e11ba51e.json
new file mode 100644
index 0000000..d026db4
--- /dev/null
+++ b/src/enm/study-FCSV-3fe25d8f-147e-359a-8587-0131e11ba51e.json
@@ -0,0 +1,80 @@
+{
+ "uuid": "FCSV-3fe25d8f-147e-359a-8587-0131e11ba51e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-cb2f11a0-4af8-318b-8a60-3908f45c2e65"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "1-Dodecanethiol"
+ }
+ },
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
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diff --git a/src/enm/study-FCSV-4182e17e-c078-334b-8b9f-227ad53be581.json b/src/enm/study-FCSV-4182e17e-c078-334b-8b9f-227ad53be581.json
new file mode 100644
index 0000000..3ad7003
--- /dev/null
+++ b/src/enm/study-FCSV-4182e17e-c078-334b-8b9f-227ad53be581.json
@@ -0,0 +1,114 @@
+{
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+ },
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+ ]
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diff --git a/src/enm/study-FCSV-41e64391-35d1-3888-a7a0-3c15e62797db.json b/src/enm/study-FCSV-41e64391-35d1-3888-a7a0-3c15e62797db.json
new file mode 100644
index 0000000..78f74e3
--- /dev/null
+++ b/src/enm/study-FCSV-41e64391-35d1-3888-a7a0-3c15e62797db.json
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+{
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+ },
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diff --git a/src/enm/study-FCSV-41fded04-3bc4-349f-8634-74e55074cdbb.json b/src/enm/study-FCSV-41fded04-3bc4-349f-8634-74e55074cdbb.json
new file mode 100644
index 0000000..19b9861
--- /dev/null
+++ b/src/enm/study-FCSV-41fded04-3bc4-349f-8634-74e55074cdbb.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-41fded04-3bc4-349f-8634-74e55074cdbb",
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+ },
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+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4204bf57-51eb-3c34-8494-07cab70af296.json b/src/enm/study-FCSV-4204bf57-51eb-3c34-8494-07cab70af296.json
new file mode 100644
index 0000000..8983145
--- /dev/null
+++ b/src/enm/study-FCSV-4204bf57-51eb-3c34-8494-07cab70af296.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-4204bf57-51eb-3c34-8494-07cab70af296",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-5b29295c-f2ab-3e5a-bb32-37caac38b002"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -20.27,
+ "errQualifier": "sd",
+ "errorValue": 6.1
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -8.29,
+ "errQualifier": "sd",
+ "errorValue": 2.64
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4207ea4d-e2d9-3e49-80c6-7be8abbb858a.json b/src/enm/study-FCSV-4207ea4d-e2d9-3e49-80c6-7be8abbb858a.json
new file mode 100644
index 0000000..576d849
--- /dev/null
+++ b/src/enm/study-FCSV-4207ea4d-e2d9-3e49-80c6-7be8abbb858a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-4207ea4d-e2d9-3e49-80c6-7be8abbb858a",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-5c14595c-0e23-3f37-aaad-9988eba09196"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4239537d-05d1-32fe-96ad-2e7c5ce70e0d.json b/src/enm/study-FCSV-4239537d-05d1-32fe-96ad-2e7c5ce70e0d.json
new file mode 100644
index 0000000..8e4d924
--- /dev/null
+++ b/src/enm/study-FCSV-4239537d-05d1-32fe-96ad-2e7c5ce70e0d.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-4239537d-05d1-32fe-96ad-2e7c5ce70e0d",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9bf04ec0-f6b6-30a6-8970-19a51968532e"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 75.8,
+ "errQualifier": "sd",
+ "errorValue": 4.31
+ }
+ },
+ {
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+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
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+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
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+ {
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+ ]
+}
diff --git a/src/enm/study-FCSV-424e229a-41db-3f70-8d27-68d21f7170ea.json b/src/enm/study-FCSV-424e229a-41db-3f70-8d27-68d21f7170ea.json
new file mode 100644
index 0000000..f37bd2c
--- /dev/null
+++ b/src/enm/study-FCSV-424e229a-41db-3f70-8d27-68d21f7170ea.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-424e229a-41db-3f70-8d27-68d21f7170ea",
+ "owner": {
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+ "uuid": "FCSV-3b96ad7a-bf2d-360d-881a-26094f498af6"
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+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
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+ },
+ "effects": [
+ {
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+ "SEQ_NUM": null
+ },
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+ }
+ },
+ {
+ "endpoint": "Density",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/cm^3",
+ "loQualifier": "",
+ "loValue": 19.1
+ }
+ },
+ {
+ "endpoint": "MW",
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+ },
+ "result": {
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+ {
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+ },
+ "result": {
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+ "loValue": 0.0
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+}
diff --git a/src/enm/study-FCSV-4261bc2e-c053-3952-973c-ac8ad4d6dc5d.json b/src/enm/study-FCSV-4261bc2e-c053-3952-973c-ac8ad4d6dc5d.json
new file mode 100644
index 0000000..4789cdb
--- /dev/null
+++ b/src/enm/study-FCSV-4261bc2e-c053-3952-973c-ac8ad4d6dc5d.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-4261bc2e-c053-3952-973c-ac8ad4d6dc5d",
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+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
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+ "Type of method": "ICP-AES",
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+ },
+ "reliability": {
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+ "r_isUsedforMSDS": "false",
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+ },
+ "effects": [
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+ "Cell": "A549"
+ },
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+ },
+ {
+ "endpoint": "Log2 transformed",
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diff --git a/src/enm/study-FCSV-4263da67-86a1-3566-b491-4fa8418d72f1.json b/src/enm/study-FCSV-4263da67-86a1-3566-b491-4fa8418d72f1.json
new file mode 100644
index 0000000..f86b1a3
--- /dev/null
+++ b/src/enm/study-FCSV-4263da67-86a1-3566-b491-4fa8418d72f1.json
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+{
+ "uuid": "FCSV-4263da67-86a1-3566-b491-4fa8418d72f1",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
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+ },
+ "protocol": {
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+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
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+ },
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+ }
+ },
+ {
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+ }
+ }
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+}
diff --git a/src/enm/study-FCSV-426adae6-b01c-3540-85c8-891b03f76ef8.json b/src/enm/study-FCSV-426adae6-b01c-3540-85c8-891b03f76ef8.json
new file mode 100644
index 0000000..8d1fb9c
--- /dev/null
+++ b/src/enm/study-FCSV-426adae6-b01c-3540-85c8-891b03f76ef8.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-426adae6-b01c-3540-85c8-891b03f76ef8",
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+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
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+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
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+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
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+ "reliability": {
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+ "effects": [
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+ "endpoint": "Spectral counts",
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+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-42d78574-6945-3e20-8410-f72f3d795878.json b/src/enm/study-FCSV-42d78574-6945-3e20-8410-f72f3d795878.json
new file mode 100644
index 0000000..48a31fc
--- /dev/null
+++ b/src/enm/study-FCSV-42d78574-6945-3e20-8410-f72f3d795878.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-42d78574-6945-3e20-8410-f72f3d795878",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-07ecc16e-528e-3904-bb96-0812dff8ea65"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.254,
+ "errQualifier": "sd",
+ "errorValue": 0.044
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4506822c-0df9-3a00-b387-fb4196503ee1.json b/src/enm/study-FCSV-4506822c-0df9-3a00-b387-fb4196503ee1.json
new file mode 100644
index 0000000..476ca12
--- /dev/null
+++ b/src/enm/study-FCSV-4506822c-0df9-3a00-b387-fb4196503ee1.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-4506822c-0df9-3a00-b387-fb4196503ee1",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-f0cbcba3-1cb5-3fa5-82cc-bfd9d1afa21d"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -28.75,
+ "errQualifier": "sd",
+ "errorValue": 5
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4616dfcd-0c8d-3582-9053-da73baeaab74.json b/src/enm/study-FCSV-4616dfcd-0c8d-3582-9053-da73baeaab74.json
new file mode 100644
index 0000000..7861795
--- /dev/null
+++ b/src/enm/study-FCSV-4616dfcd-0c8d-3582-9053-da73baeaab74.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-4616dfcd-0c8d-3582-9053-da73baeaab74",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-815715e8-0cc8-3641-897c-4530d961cfe0"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-46465b1f-0e44-35c5-afc5-1203acbbbe9a.json b/src/enm/study-FCSV-46465b1f-0e44-35c5-afc5-1203acbbbe9a.json
new file mode 100644
index 0000000..c87c5ca
--- /dev/null
+++ b/src/enm/study-FCSV-46465b1f-0e44-35c5-afc5-1203acbbbe9a.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-46465b1f-0e44-35c5-afc5-1203acbbbe9a",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-0588dd9b-6227-307f-9e6a-6b07d4717e8c"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.024,
+ "errQualifier": "sd",
+ "errorValue": 0.014
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": -5.396,
+ "errQualifier": "std",
+ "errorValue": 0.874
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-464c7d5f-d3a5-3edc-a57a-6f8f0e7067e5.json b/src/enm/study-FCSV-464c7d5f-d3a5-3edc-a57a-6f8f0e7067e5.json
new file mode 100644
index 0000000..8592a0b
--- /dev/null
+++ b/src/enm/study-FCSV-464c7d5f-d3a5-3edc-a57a-6f8f0e7067e5.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-464c7d5f-d3a5-3edc-a57a-6f8f0e7067e5",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6b15ab65-c2d3-3e58-ac04-18d8e1d45a7a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4673d1d7-35db-33f4-8db8-106e33b507c7.json b/src/enm/study-FCSV-4673d1d7-35db-33f4-8db8-106e33b507c7.json
new file mode 100644
index 0000000..21e5507
--- /dev/null
+++ b/src/enm/study-FCSV-4673d1d7-35db-33f4-8db8-106e33b507c7.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-4673d1d7-35db-33f4-8db8-106e33b507c7",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-7c42c2b4-dcbe-39a4-ae4e-0f0c41a7a5a5"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -10.71,
+ "errQualifier": "sd",
+ "errorValue": 2.28
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "pH": null
+ },
+ "result": {
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+ "loQualifier": "mean",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4695730f-2d82-3bd9-91e3-1b5186b42092.json b/src/enm/study-FCSV-4695730f-2d82-3bd9-91e3-1b5186b42092.json
new file mode 100644
index 0000000..d370581
--- /dev/null
+++ b/src/enm/study-FCSV-4695730f-2d82-3bd9-91e3-1b5186b42092.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-4695730f-2d82-3bd9-91e3-1b5186b42092",
+ "owner": {
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
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+ "MEDIUM": " "
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+ "loQualifier": "mean",
+ "loValue": 0.1,
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+ }
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+ {
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+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-46df40fd-b2d3-3e8b-9687-c8db09da32dc.json b/src/enm/study-FCSV-46df40fd-b2d3-3e8b-9687-c8db09da32dc.json
new file mode 100644
index 0000000..a585dde
--- /dev/null
+++ b/src/enm/study-FCSV-46df40fd-b2d3-3e8b-9687-c8db09da32dc.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-46df40fd-b2d3-3e8b-9687-c8db09da32dc",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
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+ "loQualifier": "mean",
+ "loValue": 0.309,
+ "errQualifier": "sd",
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+ }
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+ {
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+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
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+}
diff --git a/src/enm/study-FCSV-4727ef7c-b1df-3414-9852-a7df6d4081b4.json b/src/enm/study-FCSV-4727ef7c-b1df-3414-9852-a7df6d4081b4.json
new file mode 100644
index 0000000..ff7adbb
--- /dev/null
+++ b/src/enm/study-FCSV-4727ef7c-b1df-3414-9852-a7df6d4081b4.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-4727ef7c-b1df-3414-9852-a7df6d4081b4",
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+ "uuid": "FCSV-6aea0743-7abb-3448-85ce-961b67fca97f"
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
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+ },
+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4744a190-fcb4-3582-8cec-dae9ca725f42.json b/src/enm/study-FCSV-4744a190-fcb4-3582-8cec-dae9ca725f42.json
new file mode 100644
index 0000000..2650156
--- /dev/null
+++ b/src/enm/study-FCSV-4744a190-fcb4-3582-8cec-dae9ca725f42.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-4744a190-fcb4-3582-8cec-dae9ca725f42",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-bc488cf3-986d-34cf-9ee7-12f98873dfe4"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -33.12,
+ "errQualifier": "sd",
+ "errorValue": 2.07
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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index 0000000..b279070
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4926079e-0b48-39a0-881a-8a844ab94e56.json b/src/enm/study-FCSV-4926079e-0b48-39a0-881a-8a844ab94e56.json
new file mode 100644
index 0000000..ca506a9
--- /dev/null
+++ b/src/enm/study-FCSV-4926079e-0b48-39a0-881a-8a844ab94e56.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-4926079e-0b48-39a0-881a-8a844ab94e56",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-d677545a-5079-3793-8990-4061a6b254c5"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -12.29,
+ "errQualifier": "sd",
+ "errorValue": 6.38
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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index 0000000..5b34051
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index 0000000..950a21b
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diff --git a/src/enm/study-FCSV-4a8f0b92-ce55-323a-a96b-b24b26c9dcba.json b/src/enm/study-FCSV-4a8f0b92-ce55-323a-a96b-b24b26c9dcba.json
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diff --git a/src/enm/study-FCSV-4a9b7286-0fc1-35e9-b5c1-36185d2617ce.json b/src/enm/study-FCSV-4a9b7286-0fc1-35e9-b5c1-36185d2617ce.json
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4aee8d09-71de-39c2-94fc-dbd28f8401aa.json b/src/enm/study-FCSV-4aee8d09-71de-39c2-94fc-dbd28f8401aa.json
new file mode 100644
index 0000000..b6e75ea
--- /dev/null
+++ b/src/enm/study-FCSV-4aee8d09-71de-39c2-94fc-dbd28f8401aa.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-4aee8d09-71de-39c2-94fc-dbd28f8401aa",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8dc5c24b-2e89-3833-b94d-920674a956a0"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "11-Mercaptoundecanoic acid"
+ }
+ }
+ ]
+}
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4cf4c204-12ee-3655-859e-cbdec74f3178.json b/src/enm/study-FCSV-4cf4c204-12ee-3655-859e-cbdec74f3178.json
new file mode 100644
index 0000000..1fdbac4
--- /dev/null
+++ b/src/enm/study-FCSV-4cf4c204-12ee-3655-859e-cbdec74f3178.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-4cf4c204-12ee-3655-859e-cbdec74f3178",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9964d099-d8aa-3a89-863c-d69fc921bee2"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Thiolated L-phenylalanine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4cf92365-0c15-3538-891e-2a694c614a5a.json b/src/enm/study-FCSV-4cf92365-0c15-3538-891e-2a694c614a5a.json
new file mode 100644
index 0000000..8b9dea6
--- /dev/null
+++ b/src/enm/study-FCSV-4cf92365-0c15-3538-891e-2a694c614a5a.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-4cf92365-0c15-3538-891e-2a694c614a5a",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9a56b1e5-2e22-31c4-b979-e8e9fee728c6"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.153,
+ "errQualifier": "sd",
+ "errorValue": 0.021
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.252,
+ "errQualifier": "sd",
+ "errorValue": 0.065
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4d15b7e5-51d2-37d8-8a25-2b65f327cc3e.json b/src/enm/study-FCSV-4d15b7e5-51d2-37d8-8a25-2b65f327cc3e.json
new file mode 100644
index 0000000..d5f91ef
--- /dev/null
+++ b/src/enm/study-FCSV-4d15b7e5-51d2-37d8-8a25-2b65f327cc3e.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-4d15b7e5-51d2-37d8-8a25-2b65f327cc3e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-fb5e6048-8ee1-351d-915b-d1669681357e"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4d652b9d-1244-3fde-bc04-d6c0c1c928f4.json b/src/enm/study-FCSV-4d652b9d-1244-3fde-bc04-d6c0c1c928f4.json
new file mode 100644
index 0000000..223acf6
--- /dev/null
+++ b/src/enm/study-FCSV-4d652b9d-1244-3fde-bc04-d6c0c1c928f4.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-4d652b9d-1244-3fde-bc04-d6c0c1c928f4",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-7087aac7-6f1d-320f-bfde-5897fe91af64"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -25.65,
+ "errQualifier": "sd",
+ "errorValue": 3.65
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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diff --git a/src/enm/study-FCSV-4e40e840-836f-3280-bfd0-d22a11220969.json b/src/enm/study-FCSV-4e40e840-836f-3280-bfd0-d22a11220969.json
new file mode 100644
index 0000000..25f50fc
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+{
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+ ]
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diff --git a/src/enm/study-FCSV-4e43c74f-1906-3aee-8892-78a122917dad.json b/src/enm/study-FCSV-4e43c74f-1906-3aee-8892-78a122917dad.json
new file mode 100644
index 0000000..f6b86ad
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+{
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+ },
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
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+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
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+ ]
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+ },
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index 0000000..bc908c4
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+{
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+ },
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+ "code": "ZETA_POTENTIAL_SECTION",
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+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
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index 0000000..0dea9da
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+{
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
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+ "endpoint": "Ellman depletion assay",
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diff --git a/src/enm/study-FCSV-4f3d8f57-ae4d-30f8-8ec9-4f9b6b03170a.json b/src/enm/study-FCSV-4f3d8f57-ae4d-30f8-8ec9-4f9b6b03170a.json
new file mode 100644
index 0000000..a8674d5
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+++ b/src/enm/study-FCSV-4f3d8f57-ae4d-30f8-8ec9-4f9b6b03170a.json
@@ -0,0 +1,63 @@
+{
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+ },
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+ "category": {
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
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+ "endpoint": "Description",
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diff --git a/src/enm/study-FCSV-4f476513-74bf-3baa-900d-54aeb9c06314.json b/src/enm/study-FCSV-4f476513-74bf-3baa-900d-54aeb9c06314.json
new file mode 100644
index 0000000..4056f4b
--- /dev/null
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4f4d4ebe-5b62-36f4-a525-d94e5746a543.json b/src/enm/study-FCSV-4f4d4ebe-5b62-36f4-a525-d94e5746a543.json
new file mode 100644
index 0000000..3a01f66
--- /dev/null
+++ b/src/enm/study-FCSV-4f4d4ebe-5b62-36f4-a525-d94e5746a543.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-4f4d4ebe-5b62-36f4-a525-d94e5746a543",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ded649fa-97e1-3ec6-bb3d-623506389ee0"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -38.62,
+ "errQualifier": "sd",
+ "errorValue": 1.02
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -9.6,
+ "errQualifier": "sd",
+ "errorValue": 1.72
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-4fa8ccfb-20ba-3b6e-9174-627933ae8668.json b/src/enm/study-FCSV-4fa8ccfb-20ba-3b6e-9174-627933ae8668.json
new file mode 100644
index 0000000..a5a8831
--- /dev/null
+++ b/src/enm/study-FCSV-4fa8ccfb-20ba-3b6e-9174-627933ae8668.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-4fa8ccfb-20ba-3b6e-9174-627933ae8668",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-770a2d39-1509-3c93-b28f-1d3e345de450"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5010cfe8-fb56-37c7-ae04-a107a212461c.json b/src/enm/study-FCSV-5010cfe8-fb56-37c7-ae04-a107a212461c.json
new file mode 100644
index 0000000..b3e0776
--- /dev/null
+++ b/src/enm/study-FCSV-5010cfe8-fb56-37c7-ae04-a107a212461c.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-5010cfe8-fb56-37c7-ae04-a107a212461c",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-1c9a58a0-cd91-3636-8f7c-4fd886f8593a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.005,
+ "errQualifier": "sd",
+ "errorValue": 0.00032
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
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new file mode 100644
index 0000000..0e1f776
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+ "textValue": "Carboxymethyl-poly(ethylene glycol)-thiol (5kDa)"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5462b02b-a422-3611-8948-a5137e29b55b.json b/src/enm/study-FCSV-5462b02b-a422-3611-8948-a5137e29b55b.json
new file mode 100644
index 0000000..a95d5fe
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+++ b/src/enm/study-FCSV-5462b02b-a422-3611-8948-a5137e29b55b.json
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+{
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+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
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+ ]
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new file mode 100644
index 0000000..43b558d
--- /dev/null
+++ b/src/enm/study-FCSV-54c38205-ea81-3890-aa84-e67cf3d2396a.json
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+{
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+ },
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+ "category": {
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+ "title": "4.30 Nanomaterial surface chemistry"
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+ "endpoint": "Description",
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+ },
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
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diff --git a/src/enm/study-FCSV-555f8e31-ba21-3ba8-bcb2-50c5add11dbd.json b/src/enm/study-FCSV-555f8e31-ba21-3ba8-bcb2-50c5add11dbd.json
new file mode 100644
index 0000000..398d6c8
--- /dev/null
+++ b/src/enm/study-FCSV-555f8e31-ba21-3ba8-bcb2-50c5add11dbd.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-555f8e31-ba21-3ba8-bcb2-50c5add11dbd",
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+ "uuid": "FCSV-99734121-3347-3d4e-9bc6-67956450b140"
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
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+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
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+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
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+ "textValue": "alpha-Lipoic acid"
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diff --git a/src/enm/study-FCSV-556d0286-25c8-332b-b639-8f5dd6d1cf45.json b/src/enm/study-FCSV-556d0286-25c8-332b-b639-8f5dd6d1cf45.json
new file mode 100644
index 0000000..6eb4f5f
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+++ b/src/enm/study-FCSV-556d0286-25c8-332b-b639-8f5dd6d1cf45.json
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+{
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diff --git a/src/enm/study-FCSV-55d79ed2-4e3f-3c02-bf0e-260e92ca6a5e.json b/src/enm/study-FCSV-55d79ed2-4e3f-3c02-bf0e-260e92ca6a5e.json
new file mode 100644
index 0000000..54cdb9f
--- /dev/null
+++ b/src/enm/study-FCSV-55d79ed2-4e3f-3c02-bf0e-260e92ca6a5e.json
@@ -0,0 +1,56 @@
+{
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+ },
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-55ea6ddb-4efd-346f-989b-2693ff260aa1.json b/src/enm/study-FCSV-55ea6ddb-4efd-346f-989b-2693ff260aa1.json
new file mode 100644
index 0000000..202e1ae
--- /dev/null
+++ b/src/enm/study-FCSV-55ea6ddb-4efd-346f-989b-2693ff260aa1.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-55ea6ddb-4efd-346f-989b-2693ff260aa1",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-0d5c0fc7-de56-3507-b651-1c91bf030465"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-560416aa-2c78-3a6f-a9bf-0eaa447de64e.json b/src/enm/study-FCSV-560416aa-2c78-3a6f-a9bf-0eaa447de64e.json
new file mode 100644
index 0000000..2252fc2
--- /dev/null
+++ b/src/enm/study-FCSV-560416aa-2c78-3a6f-a9bf-0eaa447de64e.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-560416aa-2c78-3a6f-a9bf-0eaa447de64e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8e1a76df-a12d-3254-ae6b-28e20153ef59"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": 24.14,
+ "errQualifier": "sd",
+ "errorValue": 2.41
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -8.35,
+ "errQualifier": "sd",
+ "errorValue": 0.57
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-560bae11-245f-34da-9129-ee43eb809736.json b/src/enm/study-FCSV-560bae11-245f-34da-9129-ee43eb809736.json
new file mode 100644
index 0000000..b6e3299
--- /dev/null
+++ b/src/enm/study-FCSV-560bae11-245f-34da-9129-ee43eb809736.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-560bae11-245f-34da-9129-ee43eb809736",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6aea0743-7abb-3448-85ce-961b67fca97f"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 59.3,
+ "errQualifier": "sd",
+ "errorValue": 6.4
+ }
+ },
+ {
+ "endpoint": "Density",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/cm^3",
+ "loQualifier": "",
+ "loValue": 19.1
+ }
+ },
+ {
+ "endpoint": "MW",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/mol",
+ "loQualifier": "",
+ "loValue": 197
+ }
+ },
+ {
+ "endpoint": "Mol/NP",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "",
+ "loValue": 0.0
+ }
+ },
+ {
+ "endpoint": "SA/NP",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "cm^2/NP",
+ "loQualifier": "",
+ "loValue": 0.0
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-56369565-cf0c-36fd-aff9-a1829e42dfbd.json b/src/enm/study-FCSV-56369565-cf0c-36fd-aff9-a1829e42dfbd.json
new file mode 100644
index 0000000..6d3a441
--- /dev/null
+++ b/src/enm/study-FCSV-56369565-cf0c-36fd-aff9-a1829e42dfbd.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-56369565-cf0c-36fd-aff9-a1829e42dfbd",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-74492618-7ff6-39c9-b396-8d7465109083"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-56cf7f92-da2e-3318-b87a-a0e6157e5808.json b/src/enm/study-FCSV-56cf7f92-da2e-3318-b87a-a0e6157e5808.json
new file mode 100644
index 0000000..8ca5ade
--- /dev/null
+++ b/src/enm/study-FCSV-56cf7f92-da2e-3318-b87a-a0e6157e5808.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-56cf7f92-da2e-3318-b87a-a0e6157e5808",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-63da0f0e-51b8-3c56-b5d3-d4e0e9fb06a6"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
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index 0000000..3b04ce4
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-58fd76c5-684c-3616-ad55-46c16b0ff8ef.json b/src/enm/study-FCSV-58fd76c5-684c-3616-ad55-46c16b0ff8ef.json
new file mode 100644
index 0000000..a3898ef
--- /dev/null
+++ b/src/enm/study-FCSV-58fd76c5-684c-3616-ad55-46c16b0ff8ef.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-58fd76c5-684c-3616-ad55-46c16b0ff8ef",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8e1a76df-a12d-3254-ae6b-28e20153ef59"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-59010f16-6298-377c-a6a7-b636b807ce34.json b/src/enm/study-FCSV-59010f16-6298-377c-a6a7-b636b807ce34.json
new file mode 100644
index 0000000..aa2f186
--- /dev/null
+++ b/src/enm/study-FCSV-59010f16-6298-377c-a6a7-b636b807ce34.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-59010f16-6298-377c-a6a7-b636b807ce34",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9b1b9ad6-e41d-3ddd-8bea-561af1fc27aa"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Poly(vinylpyrrolidone)"
+ }
+ }
+ ]
+}
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+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
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+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "LSPR peak position (nm)",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5b2adf04-309c-3f72-ae32-ead5f869e961.json b/src/enm/study-FCSV-5b2adf04-309c-3f72-ae32-ead5f869e961.json
new file mode 100644
index 0000000..b24a5c5
--- /dev/null
+++ b/src/enm/study-FCSV-5b2adf04-309c-3f72-ae32-ead5f869e961.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-5b2adf04-309c-3f72-ae32-ead5f869e961",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9cc7dd73-d27f-35a0-a3f1-81a18429b76a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
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+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
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+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "LSPR peak position (nm)",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 518.33,
+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5b417954-3cbf-3490-8eeb-b57e5988dd9d.json b/src/enm/study-FCSV-5b417954-3cbf-3490-8eeb-b57e5988dd9d.json
new file mode 100644
index 0000000..0f1b8fb
--- /dev/null
+++ b/src/enm/study-FCSV-5b417954-3cbf-3490-8eeb-b57e5988dd9d.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-5b417954-3cbf-3490-8eeb-b57e5988dd9d",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8f0e4035-24d4-3a81-b20b-bd156f210616"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5b621862-27ce-3b95-9874-ea5ad88850b1.json b/src/enm/study-FCSV-5b621862-27ce-3b95-9874-ea5ad88850b1.json
new file mode 100644
index 0000000..d2834d1
--- /dev/null
+++ b/src/enm/study-FCSV-5b621862-27ce-3b95-9874-ea5ad88850b1.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-5b621862-27ce-3b95-9874-ea5ad88850b1",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-a3c8dce5-07ab-3ca6-91a0-84072fc24aed"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5ba55501-90f8-3ccf-96fb-9549c4ce0abe.json b/src/enm/study-FCSV-5ba55501-90f8-3ccf-96fb-9549c4ce0abe.json
new file mode 100644
index 0000000..ed4e061
--- /dev/null
+++ b/src/enm/study-FCSV-5ba55501-90f8-3ccf-96fb-9549c4ce0abe.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-5ba55501-90f8-3ccf-96fb-9549c4ce0abe",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ffe19c9e-b1a1-3f38-a149-0d587fc5b172"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Methoxy-poly(ethylene glycol)-thiol (2kDa)"
+ }
+ }
+ ]
+}
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5d34733c-6718-3418-9093-ab0863866cb3.json b/src/enm/study-FCSV-5d34733c-6718-3418-9093-ab0863866cb3.json
new file mode 100644
index 0000000..b87c3a1
--- /dev/null
+++ b/src/enm/study-FCSV-5d34733c-6718-3418-9093-ab0863866cb3.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-5d34733c-6718-3418-9093-ab0863866cb3",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ed95bb69-9fa7-3a4a-b4a4-32dd947d4d1a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": 18.17,
+ "errQualifier": "sd",
+ "errorValue": 1.53
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -8.07,
+ "errQualifier": "sd",
+ "errorValue": 1.46
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5d4d0e3e-0171-3e07-a457-eb68d06cf06c.json b/src/enm/study-FCSV-5d4d0e3e-0171-3e07-a457-eb68d06cf06c.json
new file mode 100644
index 0000000..45ed955
--- /dev/null
+++ b/src/enm/study-FCSV-5d4d0e3e-0171-3e07-a457-eb68d06cf06c.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-5d4d0e3e-0171-3e07-a457-eb68d06cf06c",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-0fe5f223-9c02-363c-a23c-70f1f36ffbec"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5e005b68-c958-3928-808f-a06027420ce5.json b/src/enm/study-FCSV-5e005b68-c958-3928-808f-a06027420ce5.json
new file mode 100644
index 0000000..836af22
--- /dev/null
+++ b/src/enm/study-FCSV-5e005b68-c958-3928-808f-a06027420ce5.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-5e005b68-c958-3928-808f-a06027420ce5",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-a7f3867d-85fc-33ab-8167-66b73c818f31"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 31.6,
+ "errQualifier": "sd",
+ "errorValue": 3.8
+ }
+ },
+ {
+ "endpoint": "Density",
+ "conditions": {
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+ },
+ "result": {
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+ "loQualifier": "",
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+ }
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+ {
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+ },
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+ }
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+}
diff --git a/src/enm/study-FCSV-5f2363eb-0ed2-33b5-8bce-adb16542a0fa.json b/src/enm/study-FCSV-5f2363eb-0ed2-33b5-8bce-adb16542a0fa.json
new file mode 100644
index 0000000..bd9a98b
--- /dev/null
+++ b/src/enm/study-FCSV-5f2363eb-0ed2-33b5-8bce-adb16542a0fa.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-5f2363eb-0ed2-33b5-8bce-adb16542a0fa",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8f5cd32a-3350-300b-91d0-87000ee5d7ee"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 240.729,
+ "errQualifier": "sd",
+ "errorValue": 1.237
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 10,
+ "errQualifier": "sd",
+ "errorValue": 0.0
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
+ "errQualifier": "sem",
+ "errorValue": 0.038
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5f322f9f-338e-3d84-a771-9fdf35457dd2.json b/src/enm/study-FCSV-5f322f9f-338e-3d84-a771-9fdf35457dd2.json
new file mode 100644
index 0000000..af65a8c
--- /dev/null
+++ b/src/enm/study-FCSV-5f322f9f-338e-3d84-a771-9fdf35457dd2.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-5f322f9f-338e-3d84-a771-9fdf35457dd2",
+ "owner": {
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+ "uuid": "FCSV-6ed95128-c2b8-3cfe-a0b4-29d2b06c6bc6"
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+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_value": null
+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
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+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 1.247,
+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5f5b3239-09fb-3b50-a084-fddf4addb8b9.json b/src/enm/study-FCSV-5f5b3239-09fb-3b50-a084-fddf4addb8b9.json
new file mode 100644
index 0000000..dfdf479
--- /dev/null
+++ b/src/enm/study-FCSV-5f5b3239-09fb-3b50-a084-fddf4addb8b9.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-5f5b3239-09fb-3b50-a084-fddf4addb8b9",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-3c5fb4b0-2e4e-3dae-9eb2-1dbfd202cd13"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-5f7f003a-8224-3515-8c33-f1a8ca1a4494.json b/src/enm/study-FCSV-5f7f003a-8224-3515-8c33-f1a8ca1a4494.json
new file mode 100644
index 0000000..7972b65
--- /dev/null
+++ b/src/enm/study-FCSV-5f7f003a-8224-3515-8c33-f1a8ca1a4494.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-5f7f003a-8224-3515-8c33-f1a8ca1a4494",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ffe19c9e-b1a1-3f38-a149-0d587fc5b172"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -6.3,
+ "errQualifier": "sd",
+ "errorValue": 2.51
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
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index 0000000..7cecf7f
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diff --git a/src/enm/study-FCSV-6427f82a-8d8d-3360-9621-0e6959543259.json b/src/enm/study-FCSV-6427f82a-8d8d-3360-9621-0e6959543259.json
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index 0000000..777ec2a
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+++ b/src/enm/study-FCSV-6427f82a-8d8d-3360-9621-0e6959543259.json
@@ -0,0 +1,77 @@
+{
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+ },
+ "protocol": {
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+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
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+ ]
+ },
+ "parameters": {
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diff --git a/src/enm/study-FCSV-646385e8-096d-3917-bfce-661b56b8ea50.json b/src/enm/study-FCSV-646385e8-096d-3917-bfce-661b56b8ea50.json
new file mode 100644
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--- /dev/null
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+{
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+ },
+ "protocol": {
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+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
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+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
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diff --git a/src/enm/study-FCSV-6469b88c-267c-3149-94a8-72b942b2ca5b.json b/src/enm/study-FCSV-6469b88c-267c-3149-94a8-72b942b2ca5b.json
new file mode 100644
index 0000000..5f0f17d
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+++ b/src/enm/study-FCSV-6469b88c-267c-3149-94a8-72b942b2ca5b.json
@@ -0,0 +1,56 @@
+{
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+ },
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+ "topcategory": "TOX",
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+ "code": "PROTEOMICS_SECTION",
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+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-64889944-534b-3c4e-85d2-d4598df38d81.json b/src/enm/study-FCSV-64889944-534b-3c4e-85d2-d4598df38d81.json
new file mode 100644
index 0000000..05e63c3
--- /dev/null
+++ b/src/enm/study-FCSV-64889944-534b-3c4e-85d2-d4598df38d81.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-64889944-534b-3c4e-85d2-d4598df38d81",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6b15ab65-c2d3-3e58-ac04-18d8e1d45a7a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.04,
+ "errQualifier": "sd",
+ "errorValue": 0.023
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
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index 0000000..8d8c74d
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+{
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+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-658682d3-8428-32e4-abc7-3b85fb6f2f67.json b/src/enm/study-FCSV-658682d3-8428-32e4-abc7-3b85fb6f2f67.json
new file mode 100644
index 0000000..9a64985
--- /dev/null
+++ b/src/enm/study-FCSV-658682d3-8428-32e4-abc7-3b85fb6f2f67.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-658682d3-8428-32e4-abc7-3b85fb6f2f67",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-99734121-3347-3d4e-9bc6-67956450b140"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 31.6,
+ "errQualifier": "sd",
+ "errorValue": 3.8
+ }
+ },
+ {
+ "endpoint": "Density",
+ "conditions": {
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diff --git a/src/enm/study-FCSV-6872c2b5-9284-3b9e-ab2f-1972f64881ca.json b/src/enm/study-FCSV-6872c2b5-9284-3b9e-ab2f-1972f64881ca.json
new file mode 100644
index 0000000..1422918
--- /dev/null
+++ b/src/enm/study-FCSV-6872c2b5-9284-3b9e-ab2f-1972f64881ca.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-6872c2b5-9284-3b9e-ab2f-1972f64881ca",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
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+ "endpoint": "Ellman depletion assay",
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+ {
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diff --git a/src/enm/study-FCSV-6931af0f-8641-3d39-922d-e884fbdac88f.json b/src/enm/study-FCSV-6931af0f-8641-3d39-922d-e884fbdac88f.json
new file mode 100644
index 0000000..995304f
--- /dev/null
+++ b/src/enm/study-FCSV-6931af0f-8641-3d39-922d-e884fbdac88f.json
@@ -0,0 +1,86 @@
+{
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+ }
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+ "year": "2014",
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+ },
+ "protocol": {
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+ "title": "4.99 Physico chemical properties (other)"
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+ "endpoint": "Absorbance.spectrophotometry.AS.",
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+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
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diff --git a/src/enm/study-FCSV-694fc7cb-2225-3cfc-a8c7-36e92133b33a.json b/src/enm/study-FCSV-694fc7cb-2225-3cfc-a8c7-36e92133b33a.json
new file mode 100644
index 0000000..873155e
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+++ b/src/enm/study-FCSV-694fc7cb-2225-3cfc-a8c7-36e92133b33a.json
@@ -0,0 +1,56 @@
+{
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+ },
+ "protocol": {
+ "topcategory": "TOX",
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+ "code": "PROTEOMICS_SECTION",
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+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
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+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-696a4de8-fd9a-3b27-98aa-b912a5d6f5c2.json b/src/enm/study-FCSV-696a4de8-fd9a-3b27-98aa-b912a5d6f5c2.json
new file mode 100644
index 0000000..59ecf94
--- /dev/null
+++ b/src/enm/study-FCSV-696a4de8-fd9a-3b27-98aa-b912a5d6f5c2.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-696a4de8-fd9a-3b27-98aa-b912a5d6f5c2",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8f5e6fcb-23b9-3222-aa6e-4afcbba47715"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.947,
+ "errQualifier": "sd",
+ "errorValue": 0.251
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
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diff --git a/src/enm/study-FCSV-69de3e28-652e-3b4d-82ea-6557f7d78480.json b/src/enm/study-FCSV-69de3e28-652e-3b4d-82ea-6557f7d78480.json
new file mode 100644
index 0000000..2b56f9b
--- /dev/null
+++ b/src/enm/study-FCSV-69de3e28-652e-3b4d-82ea-6557f7d78480.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-69de3e28-652e-3b4d-82ea-6557f7d78480",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ },
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
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+ "doi: 10.1021/nn406018q"
+ ]
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+ },
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+}
diff --git a/src/enm/study-FCSV-69f6fb23-407c-3701-8389-c5dfe81dbf6f.json b/src/enm/study-FCSV-69f6fb23-407c-3701-8389-c5dfe81dbf6f.json
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index 0000000..83a4691
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+++ b/src/enm/study-FCSV-69f6fb23-407c-3701-8389-c5dfe81dbf6f.json
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+{
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diff --git a/src/enm/study-FCSV-6a5e9ee5-e18d-3e25-8eb3-e1842023c282.json b/src/enm/study-FCSV-6a5e9ee5-e18d-3e25-8eb3-e1842023c282.json
new file mode 100644
index 0000000..4e96af3
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+++ b/src/enm/study-FCSV-6a5e9ee5-e18d-3e25-8eb3-e1842023c282.json
@@ -0,0 +1,77 @@
+{
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+ },
+ "protocol": {
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+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
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+ ]
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diff --git a/src/enm/study-FCSV-6a6882d4-b716-3774-94b3-ab9d537a5d08.json b/src/enm/study-FCSV-6a6882d4-b716-3774-94b3-ab9d537a5d08.json
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index 0000000..bec6a1d
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-6a9baa81-10e8-379f-8dc5-f79d5f8585cb.json b/src/enm/study-FCSV-6a9baa81-10e8-379f-8dc5-f79d5f8585cb.json
new file mode 100644
index 0000000..e0f52b5
--- /dev/null
+++ b/src/enm/study-FCSV-6a9baa81-10e8-379f-8dc5-f79d5f8585cb.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-6a9baa81-10e8-379f-8dc5-f79d5f8585cb",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-7c42c2b4-dcbe-39a4-ae4e-0f0c41a7a5a5"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.208,
+ "errQualifier": "sd",
+ "errorValue": 0.054
+ }
+ },
+ {
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_studyResultType": "experimental result",
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+ },
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+ },
+ "effects": [
+ {
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+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.297,
+ "errQualifier": "sd",
+ "errorValue": 0.062
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.286,
+ "errQualifier": "sd",
+ "errorValue": 0.022
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-6eb8b79e-7ebf-341d-a2ee-1c7c46dd3972.json b/src/enm/study-FCSV-6eb8b79e-7ebf-341d-a2ee-1c7c46dd3972.json
new file mode 100644
index 0000000..6ad603d
--- /dev/null
+++ b/src/enm/study-FCSV-6eb8b79e-7ebf-341d-a2ee-1c7c46dd3972.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-6eb8b79e-7ebf-341d-a2ee-1c7c46dd3972",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-50aee86c-a3a2-3c46-86bf-5ac25485fc13"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.032,
+ "errQualifier": "sd",
+ "errorValue": 0.029
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
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+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": -4.952,
+ "errQualifier": "std",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-6eefb22e-558e-3574-a943-f26ad3952c09.json b/src/enm/study-FCSV-6eefb22e-558e-3574-a943-f26ad3952c09.json
new file mode 100644
index 0000000..c59d9fc
--- /dev/null
+++ b/src/enm/study-FCSV-6eefb22e-558e-3574-a943-f26ad3952c09.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-6eefb22e-558e-3574-a943-f26ad3952c09",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-de6203a6-aea6-3910-8f49-598f80ab6a17"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_studyResultType": "experimental result",
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
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+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-6ef7ae9d-c41f-3121-ba50-ecb569dcfc49.json b/src/enm/study-FCSV-6ef7ae9d-c41f-3121-ba50-ecb569dcfc49.json
new file mode 100644
index 0000000..74ea76b
--- /dev/null
+++ b/src/enm/study-FCSV-6ef7ae9d-c41f-3121-ba50-ecb569dcfc49.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-6ef7ae9d-c41f-3121-ba50-ecb569dcfc49",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-4dd1bf89-e885-3128-abe2-9a87fbbd0242"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 0.148,
+ "errQualifier": "sd",
+ "errorValue": 0.033
+ }
+ }
+ ]
+}
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+{
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+ "loQualifier": "mean",
+ "loValue": 0.346,
+ "errQualifier": "sd",
+ "errorValue": 0.017
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-772e534d-b8fe-32c3-9616-76376bec6dc2.json b/src/enm/study-FCSV-772e534d-b8fe-32c3-9616-76376bec6dc2.json
new file mode 100644
index 0000000..b6fe0a5
--- /dev/null
+++ b/src/enm/study-FCSV-772e534d-b8fe-32c3-9616-76376bec6dc2.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-772e534d-b8fe-32c3-9616-76376bec6dc2",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-70406142-0fd6-30bd-873b-5cce39016ed5"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-7733f892-ba42-3472-a45f-fc77bb15e75e.json b/src/enm/study-FCSV-7733f892-ba42-3472-a45f-fc77bb15e75e.json
new file mode 100644
index 0000000..7c5c406
--- /dev/null
+++ b/src/enm/study-FCSV-7733f892-ba42-3472-a45f-fc77bb15e75e.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-7733f892-ba42-3472-a45f-fc77bb15e75e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9e599ca9-9a8f-3094-a97b-3fb35b08a82a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-77516e1f-3799-3677-b696-03cd9aa64aa9.json b/src/enm/study-FCSV-77516e1f-3799-3677-b696-03cd9aa64aa9.json
new file mode 100644
index 0000000..4222745
--- /dev/null
+++ b/src/enm/study-FCSV-77516e1f-3799-3677-b696-03cd9aa64aa9.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-77516e1f-3799-3677-b696-03cd9aa64aa9",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-bc2c755f-9eee-30e3-9e98-1fbb2397c980"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -32.67,
+ "errQualifier": "sd",
+ "errorValue": 3.23
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-7b0bd50a-c9fc-3179-8446-a3040a6be223.json b/src/enm/study-FCSV-7b0bd50a-c9fc-3179-8446-a3040a6be223.json
new file mode 100644
index 0000000..07f0dd3
--- /dev/null
+++ b/src/enm/study-FCSV-7b0bd50a-c9fc-3179-8446-a3040a6be223.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-7b0bd50a-c9fc-3179-8446-a3040a6be223",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-a7dbc5da-6ccd-3df5-b2f1-467f625a08cb"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.044,
+ "errQualifier": "sd",
+ "errorValue": 0.004
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
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+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": -5.737,
+ "errQualifier": "std",
+ "errorValue": 0.659
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-86fa7c5a-cb3f-3171-a641-5690df291a03.json b/src/enm/study-FCSV-86fa7c5a-cb3f-3171-a641-5690df291a03.json
new file mode 100644
index 0000000..fd4ce3c
--- /dev/null
+++ b/src/enm/study-FCSV-86fa7c5a-cb3f-3171-a641-5690df291a03.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-86fa7c5a-cb3f-3171-a641-5690df291a03",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-3b96ad7a-bf2d-360d-881a-26094f498af6"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-870d6aed-7447-324d-865a-f7b608ce0166.json b/src/enm/study-FCSV-870d6aed-7447-324d-865a-f7b608ce0166.json
new file mode 100644
index 0000000..837cab3
--- /dev/null
+++ b/src/enm/study-FCSV-870d6aed-7447-324d-865a-f7b608ce0166.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-870d6aed-7447-324d-865a-f7b608ce0166",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6046fc9f-3c73-3215-97e2-4ddcf85f41da"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 0.83,
+ "errQualifier": "sd",
+ "errorValue": 0.09
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-87695bc4-e2bb-38f8-b9f2-a2977673feaa.json b/src/enm/study-FCSV-87695bc4-e2bb-38f8-b9f2-a2977673feaa.json
new file mode 100644
index 0000000..fb9c791
--- /dev/null
+++ b/src/enm/study-FCSV-87695bc4-e2bb-38f8-b9f2-a2977673feaa.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-87695bc4-e2bb-38f8-b9f2-a2977673feaa",
+ "owner": {
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+ "uuid": "FCSV-bfa499a9-7d1a-34da-bccf-4fc30c65f03d"
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_studyResultType": "experimental result",
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+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "Z-Average Hydrodynamic Diameter",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 24.19,
+ "errQualifier": "sd",
+ "errorValue": 0.78
+ }
+ },
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
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+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
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+ },
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+ "unit": "nm",
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+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "Volume Mean Hydrodynamic Diameter",
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+ {
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+ },
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+ },
+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
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+ },
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+ }
+ },
+ {
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+ },
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+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
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+ }
+ },
+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
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+ "unit": "nm",
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+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-87744a9f-8f59-347a-b7cb-7db7dcf4dc56.json b/src/enm/study-FCSV-87744a9f-8f59-347a-b7cb-7db7dcf4dc56.json
new file mode 100644
index 0000000..a21e0aa
--- /dev/null
+++ b/src/enm/study-FCSV-87744a9f-8f59-347a-b7cb-7db7dcf4dc56.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-87744a9f-8f59-347a-b7cb-7db7dcf4dc56",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-43f0ea59-aa2f-31d8-8d87-19c95ec9be18"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 5.06,
+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-877cf51d-4921-3db3-a7a3-5c172872b61a.json b/src/enm/study-FCSV-877cf51d-4921-3db3-a7a3-5c172872b61a.json
new file mode 100644
index 0000000..ce9dfd8
--- /dev/null
+++ b/src/enm/study-FCSV-877cf51d-4921-3db3-a7a3-5c172872b61a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-877cf51d-4921-3db3-a7a3-5c172872b61a",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-cb2f11a0-4af8-318b-8a60-3908f45c2e65"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_studyResultType": "experimental result",
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
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+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-878cbd23-fdf1-3942-af3c-57bd886f1553.json b/src/enm/study-FCSV-878cbd23-fdf1-3942-af3c-57bd886f1553.json
new file mode 100644
index 0000000..345d22c
--- /dev/null
+++ b/src/enm/study-FCSV-878cbd23-fdf1-3942-af3c-57bd886f1553.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-878cbd23-fdf1-3942-af3c-57bd886f1553",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ae94c9b5-ffeb-3b3b-8464-1dfe3dbde073"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Citrate"
+ }
+ }
+ ]
+}
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+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "1-Dodecanethiol"
+ }
+ },
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "stearic acid"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8976c22d-dbe6-378a-bc46-897155990eda.json b/src/enm/study-FCSV-8976c22d-dbe6-378a-bc46-897155990eda.json
new file mode 100644
index 0000000..36fac0a
--- /dev/null
+++ b/src/enm/study-FCSV-8976c22d-dbe6-378a-bc46-897155990eda.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-8976c22d-dbe6-378a-bc46-897155990eda",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-d1731b11-29a7-3b39-bf48-000a31d9c46b"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-899abb39-bd01-3ff7-8efe-be10d63b64ac.json b/src/enm/study-FCSV-899abb39-bd01-3ff7-8efe-be10d63b64ac.json
new file mode 100644
index 0000000..065673d
--- /dev/null
+++ b/src/enm/study-FCSV-899abb39-bd01-3ff7-8efe-be10d63b64ac.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-899abb39-bd01-3ff7-8efe-be10d63b64ac",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-5b29295c-f2ab-3e5a-bb32-37caac38b002"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 23.09,
+ "errQualifier": "sd",
+ "errorValue": 1.52
+ }
+ },
+ {
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index 0000000..d899a8b
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index 0000000..0489cd4
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index 0000000..b45782d
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index 0000000..91462aa
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index 0000000..e6719e7
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8c5bcdfe-39f9-38da-ad75-5adba4db4aa3.json b/src/enm/study-FCSV-8c5bcdfe-39f9-38da-ad75-5adba4db4aa3.json
new file mode 100644
index 0000000..9951c13
--- /dev/null
+++ b/src/enm/study-FCSV-8c5bcdfe-39f9-38da-ad75-5adba4db4aa3.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-8c5bcdfe-39f9-38da-ad75-5adba4db4aa3",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ef28f16c-6ab1-3d8b-b971-37c08688701f"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.371,
+ "errQualifier": "sd",
+ "errorValue": 0.064
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
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+}
diff --git a/src/enm/study-FCSV-8c89f8b9-a382-37ae-a218-a40715465ac6.json b/src/enm/study-FCSV-8c89f8b9-a382-37ae-a218-a40715465ac6.json
new file mode 100644
index 0000000..bdd6dac
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+++ b/src/enm/study-FCSV-8c89f8b9-a382-37ae-a218-a40715465ac6.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-8c89f8b9-a382-37ae-a218-a40715465ac6",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
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+ ]
+ },
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+ },
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diff --git a/src/enm/study-FCSV-8cd113a0-46d5-300b-a410-2042a1431fae.json b/src/enm/study-FCSV-8cd113a0-46d5-300b-a410-2042a1431fae.json
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index 0000000..cfa6629
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+++ b/src/enm/study-FCSV-8cd113a0-46d5-300b-a410-2042a1431fae.json
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+{
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+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
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+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
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+ "title": "7.99 Toxicity (other)"
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+ "endpoint": "ICP-AES",
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+ ]
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diff --git a/src/enm/study-FCSV-8cfa97c2-a145-3115-8591-322a57cbc66a.json b/src/enm/study-FCSV-8cfa97c2-a145-3115-8591-322a57cbc66a.json
new file mode 100644
index 0000000..de1b661
--- /dev/null
+++ b/src/enm/study-FCSV-8cfa97c2-a145-3115-8591-322a57cbc66a.json
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+{
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+ },
+ "protocol": {
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+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
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+ },
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+ {
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+ {
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diff --git a/src/enm/study-FCSV-8d4344b6-664c-3036-a1b6-e5fbe17f4c0b.json b/src/enm/study-FCSV-8d4344b6-664c-3036-a1b6-e5fbe17f4c0b.json
new file mode 100644
index 0000000..a889038
--- /dev/null
+++ b/src/enm/study-FCSV-8d4344b6-664c-3036-a1b6-e5fbe17f4c0b.json
@@ -0,0 +1,56 @@
+{
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+ },
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+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
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+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8d6b1b26-3768-318a-b393-90f1c4d078c0.json b/src/enm/study-FCSV-8d6b1b26-3768-318a-b393-90f1c4d078c0.json
new file mode 100644
index 0000000..ac9abbb
--- /dev/null
+++ b/src/enm/study-FCSV-8d6b1b26-3768-318a-b393-90f1c4d078c0.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-8d6b1b26-3768-318a-b393-90f1c4d078c0",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-cb2f11a0-4af8-318b-8a60-3908f45c2e65"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.025,
+ "errQualifier": "sd",
+ "errorValue": 0.003
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
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diff --git a/src/enm/study-FCSV-8d9180d5-c858-324d-9a8b-ef0c317a8796.json b/src/enm/study-FCSV-8d9180d5-c858-324d-9a8b-ef0c317a8796.json
new file mode 100644
index 0000000..d9e206d
--- /dev/null
+++ b/src/enm/study-FCSV-8d9180d5-c858-324d-9a8b-ef0c317a8796.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-8d9180d5-c858-324d-9a8b-ef0c317a8796",
+ "owner": {
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+ "uuid": "FCSV-3adf8c83-83b1-3ffa-8868-b8527d83923b"
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
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+ "year": "2014",
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+ },
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+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
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+ "Description"
+ ]
+ },
+ "parameters": {
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+ "testmat_form": null
+ },
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+ "r_studyResultType": "experimental result",
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+ },
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+ "TYPE": {
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+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8da82514-9d1c-36ea-aece-2317a1382bf5.json b/src/enm/study-FCSV-8da82514-9d1c-36ea-aece-2317a1382bf5.json
new file mode 100644
index 0000000..6a2187b
--- /dev/null
+++ b/src/enm/study-FCSV-8da82514-9d1c-36ea-aece-2317a1382bf5.json
@@ -0,0 +1,80 @@
+{
+ "uuid": "FCSV-8da82514-9d1c-36ea-aece-2317a1382bf5",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-d1731b11-29a7-3b39-bf48-000a31d9c46b"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
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+ },
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+ },
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "1-Dodecanethiol"
+ }
+ },
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+ },
+ "result": {
+ "unit": null,
+ "textValue": "hexadecyltrimethylammonium bromide"
+ }
+ }
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diff --git a/src/enm/study-FCSV-8db48b46-4bfa-3b94-8d7d-3d03ef4f89a2.json b/src/enm/study-FCSV-8db48b46-4bfa-3b94-8d7d-3d03ef4f89a2.json
new file mode 100644
index 0000000..cc31610
--- /dev/null
+++ b/src/enm/study-FCSV-8db48b46-4bfa-3b94-8d7d-3d03ef4f89a2.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-8db48b46-4bfa-3b94-8d7d-3d03ef4f89a2",
+ "owner": {
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
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+ },
+ "reliability": {
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+ "effects": [
+ {
+ "endpoint": "Spectral counts",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8dc1341b-fc11-38d1-8c3e-1443f333d06f.json b/src/enm/study-FCSV-8dc1341b-fc11-38d1-8c3e-1443f333d06f.json
new file mode 100644
index 0000000..629f731
--- /dev/null
+++ b/src/enm/study-FCSV-8dc1341b-fc11-38d1-8c3e-1443f333d06f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-8dc1341b-fc11-38d1-8c3e-1443f333d06f",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-98074b22-064e-3cd7-a732-f5fa3005fa73"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8df90dbe-eb93-3d89-bc5b-ef8acf283bf4.json b/src/enm/study-FCSV-8df90dbe-eb93-3d89-bc5b-ef8acf283bf4.json
new file mode 100644
index 0000000..1f08efe
--- /dev/null
+++ b/src/enm/study-FCSV-8df90dbe-eb93-3d89-bc5b-ef8acf283bf4.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-8df90dbe-eb93-3d89-bc5b-ef8acf283bf4",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-bdd4c371-ffec-34f1-ae5b-2c60d243e867"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.135,
+ "errQualifier": "sd",
+ "errorValue": 0.06
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.078,
+ "errQualifier": "sd",
+ "errorValue": 0.019
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8e24b31d-ebbf-399a-ba3b-836d1c719260.json b/src/enm/study-FCSV-8e24b31d-ebbf-399a-ba3b-836d1c719260.json
new file mode 100644
index 0000000..5895720
--- /dev/null
+++ b/src/enm/study-FCSV-8e24b31d-ebbf-399a-ba3b-836d1c719260.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-8e24b31d-ebbf-399a-ba3b-836d1c719260",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-62d68a47-f27e-3d76-a7cf-5cacae221ec7"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8e85f9ea-756f-3bc6-afe0-ecb1aff2d056.json b/src/enm/study-FCSV-8e85f9ea-756f-3bc6-afe0-ecb1aff2d056.json
new file mode 100644
index 0000000..f81a7b7
--- /dev/null
+++ b/src/enm/study-FCSV-8e85f9ea-756f-3bc6-afe0-ecb1aff2d056.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-8e85f9ea-756f-3bc6-afe0-ecb1aff2d056",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9a56b1e5-2e22-31c4-b979-e8e9fee728c6"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 14.9,
+ "errQualifier": "sd",
+ "errorValue": 1.2
+ }
+ },
+ {
+ "endpoint": "Density",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/cm^3",
+ "loQualifier": "",
+ "loValue": 19.1
+ }
+ },
+ {
+ "endpoint": "MW",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/mol",
+ "loQualifier": "",
+ "loValue": 197
+ }
+ },
+ {
+ "endpoint": "Mol/NP",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "",
+ "loValue": 0.0
+ }
+ },
+ {
+ "endpoint": "SA/NP",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "cm^2/NP",
+ "loQualifier": "",
+ "loValue": 0.0
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8ea30a7c-6284-3602-a682-83fe0374deea.json b/src/enm/study-FCSV-8ea30a7c-6284-3602-a682-83fe0374deea.json
new file mode 100644
index 0000000..cab70a4
--- /dev/null
+++ b/src/enm/study-FCSV-8ea30a7c-6284-3602-a682-83fe0374deea.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-8ea30a7c-6284-3602-a682-83fe0374deea",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-0588dd9b-6227-307f-9e6a-6b07d4717e8c"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8ee6302a-79f0-319a-bbef-e5fb86fc2d5d.json b/src/enm/study-FCSV-8ee6302a-79f0-319a-bbef-e5fb86fc2d5d.json
new file mode 100644
index 0000000..fec5766
--- /dev/null
+++ b/src/enm/study-FCSV-8ee6302a-79f0-319a-bbef-e5fb86fc2d5d.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-8ee6302a-79f0-319a-bbef-e5fb86fc2d5d",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ff7e8515-cfad-3d76-a918-d6eeab10a91d"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-8fcd233b-1cd8-3920-b51c-aa54581d3515.json b/src/enm/study-FCSV-8fcd233b-1cd8-3920-b51c-aa54581d3515.json
new file mode 100644
index 0000000..84ea4f0
--- /dev/null
+++ b/src/enm/study-FCSV-8fcd233b-1cd8-3920-b51c-aa54581d3515.json
@@ -0,0 +1,86 @@
+{
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+ },
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+ ]
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diff --git a/src/enm/study-FCSV-8fe99120-9f7d-31ef-8410-84ee7c9e4350.json b/src/enm/study-FCSV-8fe99120-9f7d-31ef-8410-84ee7c9e4350.json
new file mode 100644
index 0000000..f9cc833
--- /dev/null
+++ b/src/enm/study-FCSV-8fe99120-9f7d-31ef-8410-84ee7c9e4350.json
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+{
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+ "year": "2014",
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+ },
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+ ]
+ },
+ "parameters": {
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+ },
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+ "unit": "cm^2/NP",
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+}
diff --git a/src/enm/study-FCSV-9016a1bc-28d2-3146-9d07-eb4eb0f33fcd.json b/src/enm/study-FCSV-9016a1bc-28d2-3146-9d07-eb4eb0f33fcd.json
new file mode 100644
index 0000000..ff18aa5
--- /dev/null
+++ b/src/enm/study-FCSV-9016a1bc-28d2-3146-9d07-eb4eb0f33fcd.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-9016a1bc-28d2-3146-9d07-eb4eb0f33fcd",
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+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
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+ },
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+ "ELEMENT_OR_GROUP": null,
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "2-Mercaptoethanesulfonate"
+ }
+ }
+ ]
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diff --git a/src/enm/study-FCSV-902cb4a8-0cdf-35fd-9d6b-2aa7e4542619.json b/src/enm/study-FCSV-902cb4a8-0cdf-35fd-9d6b-2aa7e4542619.json
new file mode 100644
index 0000000..f600efb
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+++ b/src/enm/study-FCSV-902cb4a8-0cdf-35fd-9d6b-2aa7e4542619.json
@@ -0,0 +1,56 @@
+{
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+ "year": "2014",
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+ },
+ "protocol": {
+ "topcategory": "TOX",
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+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-9040ccc7-24a1-3ae4-a191-8fc9e4bf0ca4.json b/src/enm/study-FCSV-9040ccc7-24a1-3ae4-a191-8fc9e4bf0ca4.json
new file mode 100644
index 0000000..28042af
--- /dev/null
+++ b/src/enm/study-FCSV-9040ccc7-24a1-3ae4-a191-8fc9e4bf0ca4.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-9040ccc7-24a1-3ae4-a191-8fc9e4bf0ca4",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-bfa499a9-7d1a-34da-bccf-4fc30c65f03d"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.303,
+ "errQualifier": "sd",
+ "errorValue": 0.008
+ }
+ },
+ {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-91968a66-9099-39a4-b30a-74dd06edf757.json b/src/enm/study-FCSV-91968a66-9099-39a4-b30a-74dd06edf757.json
new file mode 100644
index 0000000..4165fc4
--- /dev/null
+++ b/src/enm/study-FCSV-91968a66-9099-39a4-b30a-74dd06edf757.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-91968a66-9099-39a4-b30a-74dd06edf757",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-7ad8c003-d0ee-3ea6-9374-b6e4d2f33401"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Octadecylamine"
+ }
+ }
+ ]
+}
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-9418cd42-5fcd-37b7-93c7-31a57bb14e3e.json b/src/enm/study-FCSV-9418cd42-5fcd-37b7-93c7-31a57bb14e3e.json
new file mode 100644
index 0000000..d399eb9
--- /dev/null
+++ b/src/enm/study-FCSV-9418cd42-5fcd-37b7-93c7-31a57bb14e3e.json
@@ -0,0 +1,80 @@
+{
+ "uuid": "FCSV-9418cd42-5fcd-37b7-93c7-31a57bb14e3e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-07ecc16e-528e-3904-bb96-0812dff8ea65"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "1-Dodecanethiol"
+ }
+ },
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-96a18bc9-fa4e-3f5e-87e2-7216b60bd9ce.json b/src/enm/study-FCSV-96a18bc9-fa4e-3f5e-87e2-7216b60bd9ce.json
new file mode 100644
index 0000000..81758a0
--- /dev/null
+++ b/src/enm/study-FCSV-96a18bc9-fa4e-3f5e-87e2-7216b60bd9ce.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-96a18bc9-fa4e-3f5e-87e2-7216b60bd9ce",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-c975883b-640e-38a6-aabe-7596e3abcd95"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -18.3,
+ "errQualifier": "sd",
+ "errorValue": 1.69
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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+{
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+{
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new file mode 100644
index 0000000..530295a
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+++ b/src/enm/study-FCSV-994df969-c9d9-31e3-b263-2d8352febabd.json
@@ -0,0 +1,63 @@
+{
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+ },
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+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
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+ "textValue": "Bis(p-sulfonatophenyl)phenylphosphine"
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new file mode 100644
index 0000000..a8260e4
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+++ b/src/enm/study-FCSV-99866f7f-bab4-3d6c-a903-f74e5e8b0d9c.json
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diff --git a/src/enm/study-FCSV-99884ad6-e3f0-3474-acb6-5af7c2cabf10.json b/src/enm/study-FCSV-99884ad6-e3f0-3474-acb6-5af7c2cabf10.json
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index 0000000..ffa0a31
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+++ b/src/enm/study-FCSV-99884ad6-e3f0-3474-acb6-5af7c2cabf10.json
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+{
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+{
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new file mode 100644
index 0000000..81bb862
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-9ab4666b-3870-36f4-91d4-b719d5d80dbb.json b/src/enm/study-FCSV-9ab4666b-3870-36f4-91d4-b719d5d80dbb.json
new file mode 100644
index 0000000..3353211
--- /dev/null
+++ b/src/enm/study-FCSV-9ab4666b-3870-36f4-91d4-b719d5d80dbb.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-9ab4666b-3870-36f4-91d4-b719d5d80dbb",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-f0cbcba3-1cb5-3fa5-82cc-bfd9d1afa21d"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.211,
+ "errQualifier": "sd",
+ "errorValue": 0.005
+ }
+ },
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
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+{
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index 0000000..685e1d3
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new file mode 100644
index 0000000..799aff2
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diff --git a/src/enm/study-FCSV-9b77bb83-76ea-3415-a89f-cb67910da456.json b/src/enm/study-FCSV-9b77bb83-76ea-3415-a89f-cb67910da456.json
new file mode 100644
index 0000000..f3c6738
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diff --git a/src/enm/study-FCSV-9b8131df-0b85-32da-930a-e2c0b0fa2290.json b/src/enm/study-FCSV-9b8131df-0b85-32da-930a-e2c0b0fa2290.json
new file mode 100644
index 0000000..e375266
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-9c155e7f-e6dd-337a-b4fa-cd535cf300ff.json b/src/enm/study-FCSV-9c155e7f-e6dd-337a-b4fa-cd535cf300ff.json
new file mode 100644
index 0000000..e93c1c5
--- /dev/null
+++ b/src/enm/study-FCSV-9c155e7f-e6dd-337a-b4fa-cd535cf300ff.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-9c155e7f-e6dd-337a-b4fa-cd535cf300ff",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9043e884-a5ba-3fa6-a103-dee0c7b1b3dd"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -33.47,
+ "errQualifier": "sd",
+ "errorValue": 1.4
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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+{
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+ "title": "7.99 Toxicity (other)"
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+ ]
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+ "loQualifier": "mean",
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+ {
+ "endpoint": "Log2 transformed",
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index 0000000..ff20c64
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+++ b/src/enm/study-FCSV-9e0b0af8-ae57-34b3-9037-cb235db96390.json
@@ -0,0 +1,169 @@
+{
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
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+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
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+ "endpoint": "DLS",
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+ ]
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diff --git a/src/enm/study-FCSV-9e3a6851-1887-3001-b2e6-67e9a87d1e34.json b/src/enm/study-FCSV-9e3a6851-1887-3001-b2e6-67e9a87d1e34.json
new file mode 100644
index 0000000..1c40fb3
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+++ b/src/enm/study-FCSV-9e3a6851-1887-3001-b2e6-67e9a87d1e34.json
@@ -0,0 +1,59 @@
+{
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+ },
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diff --git a/src/enm/study-FCSV-9e445914-9cdf-3ae7-a99c-c6a9af8ab275.json b/src/enm/study-FCSV-9e445914-9cdf-3ae7-a99c-c6a9af8ab275.json
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+++ b/src/enm/study-FCSV-9e445914-9cdf-3ae7-a99c-c6a9af8ab275.json
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+{
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+ },
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diff --git a/src/enm/study-FCSV-9e4a6504-53cb-3ab0-8835-d885c020d5c4.json b/src/enm/study-FCSV-9e4a6504-53cb-3ab0-8835-d885c020d5c4.json
new file mode 100644
index 0000000..3a73e4c
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+++ b/src/enm/study-FCSV-9e4a6504-53cb-3ab0-8835-d885c020d5c4.json
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-9ebc84cd-b14b-30e0-9899-5b178440479e.json b/src/enm/study-FCSV-9ebc84cd-b14b-30e0-9899-5b178440479e.json
new file mode 100644
index 0000000..95d7034
--- /dev/null
+++ b/src/enm/study-FCSV-9ebc84cd-b14b-30e0-9899-5b178440479e.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-9ebc84cd-b14b-30e0-9899-5b178440479e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ffe19c9e-b1a1-3f38-a149-0d587fc5b172"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-9ebed2e0-7cac-3373-bd9c-2b56739c480f.json b/src/enm/study-FCSV-9ebed2e0-7cac-3373-bd9c-2b56739c480f.json
new file mode 100644
index 0000000..1248809
--- /dev/null
+++ b/src/enm/study-FCSV-9ebed2e0-7cac-3373-bd9c-2b56739c480f.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-9ebed2e0-7cac-3373-bd9c-2b56739c480f",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-cf1d4fd3-f16b-3680-96fa-0f5e4b9dd485"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.77,
+ "errQualifier": "sd",
+ "errorValue": 0.008
+ }
+ },
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
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index 0000000..a7cc0a5
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index 0000000..9bbb95d
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+{
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index 0000000..6ab0873
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index 0000000..13a9a73
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+++ b/src/enm/study-FCSV-a094c81d-0874-36db-809a-23f015767770.json
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+{
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diff --git a/src/enm/study-FCSV-a100161d-2141-3e86-ae1f-12f07b4e28ba.json b/src/enm/study-FCSV-a100161d-2141-3e86-ae1f-12f07b4e28ba.json
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index 0000000..76d6ce6
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+{
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
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diff --git a/src/enm/study-FCSV-a1283cb8-b393-31d7-a122-17b07ffbe983.json b/src/enm/study-FCSV-a1283cb8-b393-31d7-a122-17b07ffbe983.json
new file mode 100644
index 0000000..2066dac
--- /dev/null
+++ b/src/enm/study-FCSV-a1283cb8-b393-31d7-a122-17b07ffbe983.json
@@ -0,0 +1,56 @@
+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-a14367e0-3154-3219-a63b-ded8c23594c4.json b/src/enm/study-FCSV-a14367e0-3154-3219-a63b-ded8c23594c4.json
new file mode 100644
index 0000000..1f35bdd
--- /dev/null
+++ b/src/enm/study-FCSV-a14367e0-3154-3219-a63b-ded8c23594c4.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-a14367e0-3154-3219-a63b-ded8c23594c4",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-07ecc16e-528e-3904-bb96-0812dff8ea65"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 658.749,
+ "errQualifier": "sd",
+ "errorValue": 40.708
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
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diff --git a/src/enm/study-FCSV-a4dbbfaa-5c34-3983-8d56-e327c7e4d1fc.json b/src/enm/study-FCSV-a4dbbfaa-5c34-3983-8d56-e327c7e4d1fc.json
new file mode 100644
index 0000000..19d4043
--- /dev/null
+++ b/src/enm/study-FCSV-a4dbbfaa-5c34-3983-8d56-e327c7e4d1fc.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-a4dbbfaa-5c34-3983-8d56-e327c7e4d1fc",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-815715e8-0cc8-3641-897c-4530d961cfe0"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 59.3,
+ "errQualifier": "sd",
+ "errorValue": 6.4
+ }
+ },
+ {
+ "endpoint": "Density",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/cm^3",
+ "loQualifier": "",
+ "loValue": 19.1
+ }
+ },
+ {
+ "endpoint": "MW",
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/mol",
+ "loQualifier": "",
+ "loValue": 197
+ }
+ },
+ {
+ "endpoint": "Mol/NP",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "",
+ "loValue": 0.0
+ }
+ },
+ {
+ "endpoint": "SA/NP",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "cm^2/NP",
+ "loQualifier": "",
+ "loValue": 0.0
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-a4efd232-f947-3b48-9734-b9f036b21630.json b/src/enm/study-FCSV-a4efd232-f947-3b48-9734-b9f036b21630.json
new file mode 100644
index 0000000..a16f14e
--- /dev/null
+++ b/src/enm/study-FCSV-a4efd232-f947-3b48-9734-b9f036b21630.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-a4efd232-f947-3b48-9734-b9f036b21630",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-31bd6c7b-3247-3db9-93b6-59e0d3ecefa9"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-a4fdcb02-bb15-30e0-8b87-792d0b2b86bf.json b/src/enm/study-FCSV-a4fdcb02-bb15-30e0-8b87-792d0b2b86bf.json
new file mode 100644
index 0000000..ea3184e
--- /dev/null
+++ b/src/enm/study-FCSV-a4fdcb02-bb15-30e0-8b87-792d0b2b86bf.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-a4fdcb02-bb15-30e0-8b87-792d0b2b86bf",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-eec391e5-065c-32c1-89ca-3eb40260c1a8"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 7.78,
+ "errQualifier": "sd",
+ "errorValue": 0.21
+ }
+ }
+ ]
+}
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index 0000000..8afd11a
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index 0000000..d46af7a
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+{
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+ "textValue": "2-Naphthalenethiol"
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+ "textValue": "urea-modified poly(styrene co-maleic anhydride)"
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new file mode 100644
index 0000000..ee798a9
--- /dev/null
+++ b/src/enm/study-FCSV-a6402965-8825-357d-8e12-b9044fab864d.json
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+{
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+ }
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+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
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+ "category": {
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
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+ "endpoint": "ICP-AES",
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+ ]
+ },
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diff --git a/src/enm/study-FCSV-a6519c2d-d4e3-38c2-bca1-ea988a1b8b64.json b/src/enm/study-FCSV-a6519c2d-d4e3-38c2-bca1-ea988a1b8b64.json
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+{
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
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+ },
+ "protocol": {
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+ "title": "4.99 Physico chemical properties (other)"
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+ "endpoint": "Absorbance.spectrophotometry.AS.",
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+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
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diff --git a/src/enm/study-FCSV-a6b7cb43-d3bd-3335-a8a2-2a437223c310.json b/src/enm/study-FCSV-a6b7cb43-d3bd-3335-a8a2-2a437223c310.json
new file mode 100644
index 0000000..c25c484
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+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
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diff --git a/src/enm/study-FCSV-a6c55b2b-c457-36a2-94d7-dd332e77b754.json b/src/enm/study-FCSV-a6c55b2b-c457-36a2-94d7-dd332e77b754.json
new file mode 100644
index 0000000..e3bf663
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-a6dd6e78-23df-3ef5-b7bd-dda5d65b7d6c.json b/src/enm/study-FCSV-a6dd6e78-23df-3ef5-b7bd-dda5d65b7d6c.json
new file mode 100644
index 0000000..4f1ebb4
--- /dev/null
+++ b/src/enm/study-FCSV-a6dd6e78-23df-3ef5-b7bd-dda5d65b7d6c.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-a6dd6e78-23df-3ef5-b7bd-dda5d65b7d6c",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ef28f16c-6ab1-3d8b-b971-37c08688701f"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "(11-Mercaptoundecyl)tetra(ethylene glycol)"
+ }
+ }
+ ]
+}
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+++ b/src/enm/study-FCSV-a8a82abc-c5f3-37d8-80ae-4cd03d5ae33f.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-a8a82abc-c5f3-37d8-80ae-4cd03d5ae33f",
+ "owner": {
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+ "uuid": "FCSV-0fe5f223-9c02-363c-a23c-70f1f36ffbec"
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 259.044,
+ "errQualifier": "sd",
+ "errorValue": 9.797
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 11,
+ "errQualifier": "sd",
+ "errorValue": 0.0
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
+ "errQualifier": "sem",
+ "errorValue": 0.049
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-a8b23568-058a-382d-8126-f0ef820c2960.json b/src/enm/study-FCSV-a8b23568-058a-382d-8126-f0ef820c2960.json
new file mode 100644
index 0000000..65f52a4
--- /dev/null
+++ b/src/enm/study-FCSV-a8b23568-058a-382d-8126-f0ef820c2960.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-a8b23568-058a-382d-8126-f0ef820c2960",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-a3c8dce5-07ab-3ca6-91a0-84072fc24aed"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-a8c44672-9c98-3c92-aa09-3798e1ef9c32.json b/src/enm/study-FCSV-a8c44672-9c98-3c92-aa09-3798e1ef9c32.json
new file mode 100644
index 0000000..93d53c0
--- /dev/null
+++ b/src/enm/study-FCSV-a8c44672-9c98-3c92-aa09-3798e1ef9c32.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-a8c44672-9c98-3c92-aa09-3798e1ef9c32",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-acbbde2e-0238-3d4c-a2f4-7629ad478e6a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Hexadecylamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-a8e58e9b-6aaa-38cd-b4c5-1d133b631548.json b/src/enm/study-FCSV-a8e58e9b-6aaa-38cd-b4c5-1d133b631548.json
new file mode 100644
index 0000000..75be0d9
--- /dev/null
+++ b/src/enm/study-FCSV-a8e58e9b-6aaa-38cd-b4c5-1d133b631548.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-a8e58e9b-6aaa-38cd-b4c5-1d133b631548",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8f5e6fcb-23b9-3222-aa6e-4afcbba47715"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_studyResultType": "experimental result",
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-a92ad728-db13-3acf-b227-47a8ff3c12cb.json b/src/enm/study-FCSV-a92ad728-db13-3acf-b227-47a8ff3c12cb.json
new file mode 100644
index 0000000..867c585
--- /dev/null
+++ b/src/enm/study-FCSV-a92ad728-db13-3acf-b227-47a8ff3c12cb.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-a92ad728-db13-3acf-b227-47a8ff3c12cb",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-de6203a6-aea6-3910-8f49-598f80ab6a17"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.118,
+ "errQualifier": "sd",
+ "errorValue": 0.017
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
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+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.233,
+ "errQualifier": "sd",
+ "errorValue": 0.011
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.167,
+ "errQualifier": "sd",
+ "errorValue": 0.007
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-aab0d788-2996-39b3-8e2e-0378bcfaf320.json b/src/enm/study-FCSV-aab0d788-2996-39b3-8e2e-0378bcfaf320.json
new file mode 100644
index 0000000..415c0f3
--- /dev/null
+++ b/src/enm/study-FCSV-aab0d788-2996-39b3-8e2e-0378bcfaf320.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-aab0d788-2996-39b3-8e2e-0378bcfaf320",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-4c523ea9-f3e8-32f4-9152-f73400aedb67"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-aafdefc3-26bf-3153-80f6-97cd2d42938e.json b/src/enm/study-FCSV-aafdefc3-26bf-3153-80f6-97cd2d42938e.json
new file mode 100644
index 0000000..9738729
--- /dev/null
+++ b/src/enm/study-FCSV-aafdefc3-26bf-3153-80f6-97cd2d42938e.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-aafdefc3-26bf-3153-80f6-97cd2d42938e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6405ef25-683e-3763-a4e3-f56eb93174e4"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.113,
+ "errQualifier": "sd",
+ "errorValue": 0.009
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-ab20662a-6678-3f65-bdd2-dbfa99536590.json b/src/enm/study-FCSV-ab20662a-6678-3f65-bdd2-dbfa99536590.json
new file mode 100644
index 0000000..bd355d7
--- /dev/null
+++ b/src/enm/study-FCSV-ab20662a-6678-3f65-bdd2-dbfa99536590.json
@@ -0,0 +1,73 @@
+{
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+ "category": {
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+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
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diff --git a/src/enm/study-FCSV-ab307f0b-73df-3ce4-8ba7-92a64c53a907.json b/src/enm/study-FCSV-ab307f0b-73df-3ce4-8ba7-92a64c53a907.json
new file mode 100644
index 0000000..68c9acd
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+++ b/src/enm/study-FCSV-ab307f0b-73df-3ce4-8ba7-92a64c53a907.json
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+{
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
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+ "owner": null
+ },
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+ "category": {
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+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
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+ },
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diff --git a/src/enm/study-FCSV-ab77fa85-c3f3-338e-94ae-d7eefd4faeb0.json b/src/enm/study-FCSV-ab77fa85-c3f3-338e-94ae-d7eefd4faeb0.json
new file mode 100644
index 0000000..748940e
--- /dev/null
+++ b/src/enm/study-FCSV-ab77fa85-c3f3-338e-94ae-d7eefd4faeb0.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-ab77fa85-c3f3-338e-94ae-d7eefd4faeb0",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
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+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
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+ "TYPE": {
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+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Thiolated poly(L-lysine)"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-abc10ee8-47a8-3ff4-ae6c-f2e59057b91c.json b/src/enm/study-FCSV-abc10ee8-47a8-3ff4-ae6c-f2e59057b91c.json
new file mode 100644
index 0000000..147708f
--- /dev/null
+++ b/src/enm/study-FCSV-abc10ee8-47a8-3ff4-ae6c-f2e59057b91c.json
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+{
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diff --git a/src/enm/study-FCSV-abc74a96-cca2-37c5-a408-96e10b93202f.json b/src/enm/study-FCSV-abc74a96-cca2-37c5-a408-96e10b93202f.json
new file mode 100644
index 0000000..3dc865f
--- /dev/null
+++ b/src/enm/study-FCSV-abc74a96-cca2-37c5-a408-96e10b93202f.json
@@ -0,0 +1,56 @@
+{
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+ },
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-ac398b7b-bfe6-3319-b504-012ac7fa628c.json b/src/enm/study-FCSV-ac398b7b-bfe6-3319-b504-012ac7fa628c.json
new file mode 100644
index 0000000..c4b890b
--- /dev/null
+++ b/src/enm/study-FCSV-ac398b7b-bfe6-3319-b504-012ac7fa628c.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-ac398b7b-bfe6-3319-b504-012ac7fa628c",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-206b1a13-e02a-38a0-88ec-d5a8bfdabc55"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -3.07,
+ "errQualifier": "sd",
+ "errorValue": 1.08
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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diff --git a/src/enm/study-FCSV-adf77f30-ee23-39c9-a5b8-aa48762ba537.json b/src/enm/study-FCSV-adf77f30-ee23-39c9-a5b8-aa48762ba537.json
new file mode 100644
index 0000000..17695ed
--- /dev/null
+++ b/src/enm/study-FCSV-adf77f30-ee23-39c9-a5b8-aa48762ba537.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-adf77f30-ee23-39c9-a5b8-aa48762ba537",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-1c9a58a0-cd91-3636-8f7c-4fd886f8593a"
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "testmat_form": null
+ },
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+ },
+ "effects": [
+ {
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+ "ELEMENT_OR_GROUP": null,
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Peptide sequence 'CALNN'"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-ae224991-49f6-35d0-b874-d485fed70bf8.json b/src/enm/study-FCSV-ae224991-49f6-35d0-b874-d485fed70bf8.json
new file mode 100644
index 0000000..b72461f
--- /dev/null
+++ b/src/enm/study-FCSV-ae224991-49f6-35d0-b874-d485fed70bf8.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-ae224991-49f6-35d0-b874-d485fed70bf8",
+ "owner": {
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+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
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+ },
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+ "TYPE": {
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+ "textValue": "[Au]"
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diff --git a/src/enm/study-FCSV-ae3bb801-ed8c-386c-97bb-002708caded5.json b/src/enm/study-FCSV-ae3bb801-ed8c-386c-97bb-002708caded5.json
new file mode 100644
index 0000000..32985f7
--- /dev/null
+++ b/src/enm/study-FCSV-ae3bb801-ed8c-386c-97bb-002708caded5.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-ae3bb801-ed8c-386c-97bb-002708caded5",
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+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
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+ },
+ "reliability": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-ae8dd949-973b-399e-9e34-372bccff6fec.json b/src/enm/study-FCSV-ae8dd949-973b-399e-9e34-372bccff6fec.json
new file mode 100644
index 0000000..4c1cf42
--- /dev/null
+++ b/src/enm/study-FCSV-ae8dd949-973b-399e-9e34-372bccff6fec.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-ae8dd949-973b-399e-9e34-372bccff6fec",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-edc7f198-f391-328e-aa68-7d3f00b62af5"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-aef9fcc3-43d5-3b20-8894-96ac92ccada7.json b/src/enm/study-FCSV-aef9fcc3-43d5-3b20-8894-96ac92ccada7.json
new file mode 100644
index 0000000..6383c75
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+++ b/src/enm/study-FCSV-aef9fcc3-43d5-3b20-8894-96ac92ccada7.json
@@ -0,0 +1,73 @@
+{
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+ "year": "2014",
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+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
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+ ]
+ },
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diff --git a/src/enm/study-FCSV-af1b9c25-dcf3-36de-ba20-06627f218d84.json b/src/enm/study-FCSV-af1b9c25-dcf3-36de-ba20-06627f218d84.json
new file mode 100644
index 0000000..0bb595c
--- /dev/null
+++ b/src/enm/study-FCSV-af1b9c25-dcf3-36de-ba20-06627f218d84.json
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+{
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+ }
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
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+ },
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+ "title": "7.99 Toxicity (other)"
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+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
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+ "loQualifier": "mean",
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+ }
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diff --git a/src/enm/study-FCSV-af200471-3083-3ad7-8454-65c0bf67b288.json b/src/enm/study-FCSV-af200471-3083-3ad7-8454-65c0bf67b288.json
new file mode 100644
index 0000000..2e5cc55
--- /dev/null
+++ b/src/enm/study-FCSV-af200471-3083-3ad7-8454-65c0bf67b288.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-af200471-3083-3ad7-8454-65c0bf67b288",
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+ }
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+ "year": "2014",
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+ },
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+ "title": "4.30 Nanomaterial surface chemistry"
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+ "endpoint": "Description",
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+ "textValue": "[Au]"
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diff --git a/src/enm/study-FCSV-af6e6d70-3193-3a44-90ba-aa3597d7d108.json b/src/enm/study-FCSV-af6e6d70-3193-3a44-90ba-aa3597d7d108.json
new file mode 100644
index 0000000..0188a53
--- /dev/null
+++ b/src/enm/study-FCSV-af6e6d70-3193-3a44-90ba-aa3597d7d108.json
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+{
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+ "year": "2014",
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
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+ "endpoint": "Ellman depletion assay",
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+ {
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diff --git a/src/enm/study-FCSV-b00fbaf0-34bd-3b31-a619-aed633393790.json b/src/enm/study-FCSV-b00fbaf0-34bd-3b31-a619-aed633393790.json
new file mode 100644
index 0000000..ae99dd0
--- /dev/null
+++ b/src/enm/study-FCSV-b00fbaf0-34bd-3b31-a619-aed633393790.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-b00fbaf0-34bd-3b31-a619-aed633393790",
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+ },
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diff --git a/src/enm/study-FCSV-b059c1b2-84de-346d-b624-a19fe8f101f4.json b/src/enm/study-FCSV-b059c1b2-84de-346d-b624-a19fe8f101f4.json
new file mode 100644
index 0000000..5f95021
--- /dev/null
+++ b/src/enm/study-FCSV-b059c1b2-84de-346d-b624-a19fe8f101f4.json
@@ -0,0 +1,56 @@
+{
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+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b0afd1e5-85f9-394f-8016-53bbdd53fa49.json b/src/enm/study-FCSV-b0afd1e5-85f9-394f-8016-53bbdd53fa49.json
new file mode 100644
index 0000000..d1e5abe
--- /dev/null
+++ b/src/enm/study-FCSV-b0afd1e5-85f9-394f-8016-53bbdd53fa49.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-b0afd1e5-85f9-394f-8016-53bbdd53fa49",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-4dd1bf89-e885-3128-abe2-9a87fbbd0242"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.053,
+ "errQualifier": "sd",
+ "errorValue": 0.04
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
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+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
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+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_studyResultType": "experimental result",
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+ },
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+ },
+ "effects": [
+ {
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+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
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+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 462.138,
+ "errQualifier": "sd",
+ "errorValue": 6.828
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
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+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 9,
+ "errQualifier": "sd",
+ "errorValue": 0.0
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
+ "errQualifier": "sem",
+ "errorValue": 0.015
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b23c13e0-7af7-32a9-aa14-c2780c8a1d21.json b/src/enm/study-FCSV-b23c13e0-7af7-32a9-aa14-c2780c8a1d21.json
new file mode 100644
index 0000000..181c925
--- /dev/null
+++ b/src/enm/study-FCSV-b23c13e0-7af7-32a9-aa14-c2780c8a1d21.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-b23c13e0-7af7-32a9-aa14-c2780c8a1d21",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-d6c56b3e-71a2-330b-92b6-9c90e6046eaa"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Thiolated L-threonine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b26c5d41-1ba0-3e03-873e-7c634e382973.json b/src/enm/study-FCSV-b26c5d41-1ba0-3e03-873e-7c634e382973.json
new file mode 100644
index 0000000..a3a373e
--- /dev/null
+++ b/src/enm/study-FCSV-b26c5d41-1ba0-3e03-873e-7c634e382973.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-b26c5d41-1ba0-3e03-873e-7c634e382973",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-de7a4a31-ee94-313e-bfc4-acc11f0b56ec"
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+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
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+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.102,
+ "errQualifier": "sd",
+ "errorValue": 0.009
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": -3.291,
+ "errQualifier": "std",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b26eb174-9fba-360e-846a-9f06dd656982.json b/src/enm/study-FCSV-b26eb174-9fba-360e-846a-9f06dd656982.json
new file mode 100644
index 0000000..7b82f79
--- /dev/null
+++ b/src/enm/study-FCSV-b26eb174-9fba-360e-846a-9f06dd656982.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-b26eb174-9fba-360e-846a-9f06dd656982",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-924a51b9-97d3-31fb-b289-52688d9d0d3c"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ },
+ "effects": [
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+ "MEDIUM": " ",
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+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -22.2,
+ "errQualifier": "sd",
+ "errorValue": 4.69
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -7.2,
+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b28a6e14-bca0-320a-b228-cf2ba3b25061.json b/src/enm/study-FCSV-b28a6e14-bca0-320a-b228-cf2ba3b25061.json
new file mode 100644
index 0000000..0af9b18
--- /dev/null
+++ b/src/enm/study-FCSV-b28a6e14-bca0-320a-b228-cf2ba3b25061.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-b28a6e14-bca0-320a-b228-cf2ba3b25061",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-a7f3867d-85fc-33ab-8167-66b73c818f31"
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+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_studyResultType": "experimental result",
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
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+ },
+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b2ac8863-ce4e-325c-85ea-d53529010256.json b/src/enm/study-FCSV-b2ac8863-ce4e-325c-85ea-d53529010256.json
new file mode 100644
index 0000000..c5528a8
--- /dev/null
+++ b/src/enm/study-FCSV-b2ac8863-ce4e-325c-85ea-d53529010256.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-b2ac8863-ce4e-325c-85ea-d53529010256",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9bf04ec0-f6b6-30a6-8970-19a51968532e"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -36.08,
+ "errQualifier": "sd",
+ "errorValue": 4.92
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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diff --git a/src/enm/study-FCSV-b34adcc6-64c8-31a3-adb5-c7bad51a0f11.json b/src/enm/study-FCSV-b34adcc6-64c8-31a3-adb5-c7bad51a0f11.json
new file mode 100644
index 0000000..2ddc36c
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+++ b/src/enm/study-FCSV-b34adcc6-64c8-31a3-adb5-c7bad51a0f11.json
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+{
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diff --git a/src/enm/study-FCSV-b3782a0c-efb1-3fc8-a2ca-3b8e302f1498.json b/src/enm/study-FCSV-b3782a0c-efb1-3fc8-a2ca-3b8e302f1498.json
new file mode 100644
index 0000000..ca8e4da
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+++ b/src/enm/study-FCSV-b3782a0c-efb1-3fc8-a2ca-3b8e302f1498.json
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+{
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+ },
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+ ]
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diff --git a/src/enm/study-FCSV-b3a1d0d3-b215-30f4-abc9-4447faac08f9.json b/src/enm/study-FCSV-b3a1d0d3-b215-30f4-abc9-4447faac08f9.json
new file mode 100644
index 0000000..e103afd
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+{
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+ "title": "4.99 Physico chemical properties (other)"
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+ "endpoint": "Absorbance.spectrophotometry.AS.",
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+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
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diff --git a/src/enm/study-FCSV-b3bf9410-d0c1-364b-a77e-502b9f2f593a.json b/src/enm/study-FCSV-b3bf9410-d0c1-364b-a77e-502b9f2f593a.json
new file mode 100644
index 0000000..55e1cfa
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+++ b/src/enm/study-FCSV-b3bf9410-d0c1-364b-a77e-502b9f2f593a.json
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+{
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+ },
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b3e9b8ae-0930-3d79-8981-7a506fda1b2d.json b/src/enm/study-FCSV-b3e9b8ae-0930-3d79-8981-7a506fda1b2d.json
new file mode 100644
index 0000000..05fd3fa
--- /dev/null
+++ b/src/enm/study-FCSV-b3e9b8ae-0930-3d79-8981-7a506fda1b2d.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-b3e9b8ae-0930-3d79-8981-7a506fda1b2d",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-3b96ad7a-bf2d-360d-881a-26094f498af6"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
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diff --git a/src/enm/study-FCSV-b5183d27-2e45-37c9-984a-f7f9347979e8.json b/src/enm/study-FCSV-b5183d27-2e45-37c9-984a-f7f9347979e8.json
new file mode 100644
index 0000000..f828334
--- /dev/null
+++ b/src/enm/study-FCSV-b5183d27-2e45-37c9-984a-f7f9347979e8.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-b5183d27-2e45-37c9-984a-f7f9347979e8",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8e1a76df-a12d-3254-ae6b-28e20153ef59"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 743.369,
+ "errQualifier": "sd",
+ "errorValue": 125.858
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 8,
+ "errQualifier": "sd",
+ "errorValue": 1
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
+ "errQualifier": "sem",
+ "errorValue": 0.026
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b52283ea-c3af-3428-9fb3-6c277d796ee4.json b/src/enm/study-FCSV-b52283ea-c3af-3428-9fb3-6c277d796ee4.json
new file mode 100644
index 0000000..ebb6abb
--- /dev/null
+++ b/src/enm/study-FCSV-b52283ea-c3af-3428-9fb3-6c277d796ee4.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-b52283ea-c3af-3428-9fb3-6c277d796ee4",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8a45dec8-a551-33cc-a7ac-7750d9f30389"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 2.389,
+ "errQualifier": "sd",
+ "errorValue": 0.655
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b55edfef-60af-3fb3-bd03-babc2b7c5917.json b/src/enm/study-FCSV-b55edfef-60af-3fb3-bd03-babc2b7c5917.json
new file mode 100644
index 0000000..eaeaaec
--- /dev/null
+++ b/src/enm/study-FCSV-b55edfef-60af-3fb3-bd03-babc2b7c5917.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-b55edfef-60af-3fb3-bd03-babc2b7c5917",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-07629748-9b8e-381b-a4e6-79b495404e02"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b55f70a2-7dc5-3a10-878f-58333168fb65.json b/src/enm/study-FCSV-b55f70a2-7dc5-3a10-878f-58333168fb65.json
new file mode 100644
index 0000000..74356e6
--- /dev/null
+++ b/src/enm/study-FCSV-b55f70a2-7dc5-3a10-878f-58333168fb65.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-b55f70a2-7dc5-3a10-878f-58333168fb65",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-a4df7f03-50e1-387c-b0b7-2ce62ed03a8c"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -30.57,
+ "errQualifier": "sd",
+ "errorValue": 5.04
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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+{
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index 0000000..03d4acc
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b94e532f-3bfd-3b3e-a0dc-3fc3424d6079.json b/src/enm/study-FCSV-b94e532f-3bfd-3b3e-a0dc-3fc3424d6079.json
new file mode 100644
index 0000000..54f590a
--- /dev/null
+++ b/src/enm/study-FCSV-b94e532f-3bfd-3b3e-a0dc-3fc3424d6079.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-b94e532f-3bfd-3b3e-a0dc-3fc3424d6079",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-de6203a6-aea6-3910-8f49-598f80ab6a17"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.304,
+ "errQualifier": "sd",
+ "errorValue": 0.005
+ }
+ },
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.311,
+ "errQualifier": "sd",
+ "errorValue": 0.004
+ }
+ },
+ {
+ "endpoint": "LSPR peak position (nm)",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 527.13,
+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b95a7fda-2885-373b-a363-16779a2758e5.json b/src/enm/study-FCSV-b95a7fda-2885-373b-a363-16779a2758e5.json
new file mode 100644
index 0000000..e6c876c
--- /dev/null
+++ b/src/enm/study-FCSV-b95a7fda-2885-373b-a363-16779a2758e5.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-b95a7fda-2885-373b-a363-16779a2758e5",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-4026a85b-f254-3d35-bd77-c634d38e4a22"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.293,
+ "errQualifier": "sd",
+ "errorValue": 0.082
+ }
+ },
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
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+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "LSPR peak position (nm)",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 520.6,
+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b99ae7e0-5ee4-366b-9046-91dd87086d5c.json b/src/enm/study-FCSV-b99ae7e0-5ee4-366b-9046-91dd87086d5c.json
new file mode 100644
index 0000000..37a91b2
--- /dev/null
+++ b/src/enm/study-FCSV-b99ae7e0-5ee4-366b-9046-91dd87086d5c.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-b99ae7e0-5ee4-366b-9046-91dd87086d5c",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-1180669a-fc30-3bc1-b53e-6a200c4248e4"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-b9a50179-8b81-3bde-8f21-91cdb9189e25.json b/src/enm/study-FCSV-b9a50179-8b81-3bde-8f21-91cdb9189e25.json
new file mode 100644
index 0000000..4bd4ff0
--- /dev/null
+++ b/src/enm/study-FCSV-b9a50179-8b81-3bde-8f21-91cdb9189e25.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-b9a50179-8b81-3bde-8f21-91cdb9189e25",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9a56b1e5-2e22-31c4-b979-e8e9fee728c6"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.322,
+ "errQualifier": "sd",
+ "errorValue": 0.006
+ }
+ },
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
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diff --git a/src/enm/study-FCSV-bb1efb08-234a-3c89-8352-e7f72785a02e.json b/src/enm/study-FCSV-bb1efb08-234a-3c89-8352-e7f72785a02e.json
new file mode 100644
index 0000000..d5784a3
--- /dev/null
+++ b/src/enm/study-FCSV-bb1efb08-234a-3c89-8352-e7f72785a02e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-bb1efb08-234a-3c89-8352-e7f72785a02e",
+ "owner": {
+ "substance": {
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
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+ "citation": {
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+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
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+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
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+ },
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diff --git a/src/enm/study-FCSV-bb647692-f1e0-3c97-9997-5b07d2c495fa.json b/src/enm/study-FCSV-bb647692-f1e0-3c97-9997-5b07d2c495fa.json
new file mode 100644
index 0000000..2c03e79
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+{
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+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
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+ },
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diff --git a/src/enm/study-FCSV-bb70e58e-589f-3349-9d3a-b1321ca37bd5.json b/src/enm/study-FCSV-bb70e58e-589f-3349-9d3a-b1321ca37bd5.json
new file mode 100644
index 0000000..f0d5bac
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+++ b/src/enm/study-FCSV-bb70e58e-589f-3349-9d3a-b1321ca37bd5.json
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+{
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+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
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+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
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+ },
+ "reliability": {
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+ "effects": [
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+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-bb7493a6-a0f7-3ab2-9ccc-ed9766a4767e.json b/src/enm/study-FCSV-bb7493a6-a0f7-3ab2-9ccc-ed9766a4767e.json
new file mode 100644
index 0000000..0d19d29
--- /dev/null
+++ b/src/enm/study-FCSV-bb7493a6-a0f7-3ab2-9ccc-ed9766a4767e.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-bb7493a6-a0f7-3ab2-9ccc-ed9766a4767e",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8619e6db-2c01-389e-b05b-e75273d18359"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-bb795ff5-8fe2-3edc-8e08-14e23ccd8a96.json b/src/enm/study-FCSV-bb795ff5-8fe2-3edc-8e08-14e23ccd8a96.json
new file mode 100644
index 0000000..27ca50a
--- /dev/null
+++ b/src/enm/study-FCSV-bb795ff5-8fe2-3edc-8e08-14e23ccd8a96.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-bb795ff5-8fe2-3edc-8e08-14e23ccd8a96",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-93c29ebf-e80e-354c-893f-923385c72858"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
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index 0000000..d01e388
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+{
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+ },
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+{
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+ "title": "7.99 Toxicity (other)"
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+ "doi: 10.1021/nn406018q"
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+{
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
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+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
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diff --git a/src/enm/study-FCSV-bca73fcc-5eb8-33d6-881a-83ede6574146.json b/src/enm/study-FCSV-bca73fcc-5eb8-33d6-881a-83ede6574146.json
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index 0000000..36925ec
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+{
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diff --git a/src/enm/study-FCSV-bce0ea48-6572-331a-be1e-2e7f06857932.json b/src/enm/study-FCSV-bce0ea48-6572-331a-be1e-2e7f06857932.json
new file mode 100644
index 0000000..d6fdd92
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+++ b/src/enm/study-FCSV-bce0ea48-6572-331a-be1e-2e7f06857932.json
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-bcf5b80e-489e-3365-aac0-8450d93be79c.json b/src/enm/study-FCSV-bcf5b80e-489e-3365-aac0-8450d93be79c.json
new file mode 100644
index 0000000..7096626
--- /dev/null
+++ b/src/enm/study-FCSV-bcf5b80e-489e-3365-aac0-8450d93be79c.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-bcf5b80e-489e-3365-aac0-8450d93be79c",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ff7e8515-cfad-3d76-a918-d6eeab10a91d"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": 12.19,
+ "errQualifier": "sd",
+ "errorValue": 3.54
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
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index 0000000..61fc4f0
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-bf510912-1531-3e75-8bfa-5d05a57388a0.json b/src/enm/study-FCSV-bf510912-1531-3e75-8bfa-5d05a57388a0.json
new file mode 100644
index 0000000..eda687e
--- /dev/null
+++ b/src/enm/study-FCSV-bf510912-1531-3e75-8bfa-5d05a57388a0.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-bf510912-1531-3e75-8bfa-5d05a57388a0",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-cf1d4fd3-f16b-3680-96fa-0f5e4b9dd485"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
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+ "uuid": "FCSV-a7dbc5da-6ccd-3df5-b2f1-467f625a08cb"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-c5ba0dbb-8bad-3aba-8a1a-9816d7c994d6.json b/src/enm/study-FCSV-c5ba0dbb-8bad-3aba-8a1a-9816d7c994d6.json
new file mode 100644
index 0000000..bf700b2
--- /dev/null
+++ b/src/enm/study-FCSV-c5ba0dbb-8bad-3aba-8a1a-9816d7c994d6.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-c5ba0dbb-8bad-3aba-8a1a-9816d7c994d6",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-0e958d54-f957-37d2-91d1-ee8d9961548e"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.434,
+ "errQualifier": "sd",
+ "errorValue": 0.019
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-c70ebd26-bc4a-3345-8f14-5d1d53faeae0.json b/src/enm/study-FCSV-c70ebd26-bc4a-3345-8f14-5d1d53faeae0.json
new file mode 100644
index 0000000..5335569
--- /dev/null
+++ b/src/enm/study-FCSV-c70ebd26-bc4a-3345-8f14-5d1d53faeae0.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-c70ebd26-bc4a-3345-8f14-5d1d53faeae0",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-2ed7ebf8-d11d-3f39-8f05-b0132ec4d7e0"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-c7524fd7-6b2e-39b6-8ba6-bc6e6739d138.json b/src/enm/study-FCSV-c7524fd7-6b2e-39b6-8ba6-bc6e6739d138.json
new file mode 100644
index 0000000..5168869
--- /dev/null
+++ b/src/enm/study-FCSV-c7524fd7-6b2e-39b6-8ba6-bc6e6739d138.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-c7524fd7-6b2e-39b6-8ba6-bc6e6739d138",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ff7e8515-cfad-3d76-a918-d6eeab10a91d"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.41,
+ "errQualifier": "sd",
+ "errorValue": 0.035
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
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+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-ce0b214c-f85d-3e7f-90df-ba43c49d311b.json b/src/enm/study-FCSV-ce0b214c-f85d-3e7f-90df-ba43c49d311b.json
new file mode 100644
index 0000000..7e7874c
--- /dev/null
+++ b/src/enm/study-FCSV-ce0b214c-f85d-3e7f-90df-ba43c49d311b.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-ce0b214c-f85d-3e7f-90df-ba43c49d311b",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-e4b9ce55-bbeb-368b-a1d4-e591b7df742e"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 3.615,
+ "errQualifier": "sd",
+ "errorValue": 0.619
+ }
+ }
+ ]
+}
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index 0000000..c1bf39a
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+{
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index 0000000..f9beea1
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index 0000000..21bcbdd
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index 0000000..78e0bc2
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+{
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d2815d0a-c5cf-35db-a4aa-44305850d8d9.json b/src/enm/study-FCSV-d2815d0a-c5cf-35db-a4aa-44305850d8d9.json
new file mode 100644
index 0000000..934d59e
--- /dev/null
+++ b/src/enm/study-FCSV-d2815d0a-c5cf-35db-a4aa-44305850d8d9.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-d2815d0a-c5cf-35db-a4aa-44305850d8d9",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-5c14595c-0e23-3f37-aaad-9988eba09196"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 3.835,
+ "errQualifier": "sd",
+ "errorValue": 0.399
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d2c53ee8-4d19-3ccd-ae69-57611b2b2b30.json b/src/enm/study-FCSV-d2c53ee8-4d19-3ccd-ae69-57611b2b2b30.json
new file mode 100644
index 0000000..f6cb3cd
--- /dev/null
+++ b/src/enm/study-FCSV-d2c53ee8-4d19-3ccd-ae69-57611b2b2b30.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-d2c53ee8-4d19-3ccd-ae69-57611b2b2b30",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ff7e8515-cfad-3d76-a918-d6eeab10a91d"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.507,
+ "errQualifier": "sd",
+ "errorValue": 0.059
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": -0.98,
+ "errQualifier": "std",
+ "errorValue": 0.168
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d2cd2f10-7905-308e-a47f-8471a38cfed5.json b/src/enm/study-FCSV-d2cd2f10-7905-308e-a47f-8471a38cfed5.json
new file mode 100644
index 0000000..fd6acea
--- /dev/null
+++ b/src/enm/study-FCSV-d2cd2f10-7905-308e-a47f-8471a38cfed5.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-d2cd2f10-7905-308e-a47f-8471a38cfed5",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6b272721-ed04-31bd-a4d4-cb6496140e85"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
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+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.058,
+ "errQualifier": "sd",
+ "errorValue": 0.03
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.282,
+ "errQualifier": "sd",
+ "errorValue": 0.004
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d2ecb7cc-5af7-35b6-9c66-ecc065e7a838.json b/src/enm/study-FCSV-d2ecb7cc-5af7-35b6-9c66-ecc065e7a838.json
new file mode 100644
index 0000000..e210a36
--- /dev/null
+++ b/src/enm/study-FCSV-d2ecb7cc-5af7-35b6-9c66-ecc065e7a838.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-d2ecb7cc-5af7-35b6-9c66-ecc065e7a838",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ae94c9b5-ffeb-3b3b-8464-1dfe3dbde073"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
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+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d2f2b53f-f680-3583-833e-cf85631d5405.json b/src/enm/study-FCSV-d2f2b53f-f680-3583-833e-cf85631d5405.json
new file mode 100644
index 0000000..91e5766
--- /dev/null
+++ b/src/enm/study-FCSV-d2f2b53f-f680-3583-833e-cf85631d5405.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-d2f2b53f-f680-3583-833e-cf85631d5405",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-2b9a077f-bef3-3ffd-a83a-77dd85db129a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 1.951,
+ "errQualifier": "sd",
+ "errorValue": 0.62
+ }
+ }
+ ]
+}
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+{
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+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 11,
+ "errQualifier": "sd",
+ "errorValue": 1
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
+ "errQualifier": "sem",
+ "errorValue": 0.006
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d471cef1-160a-3124-97da-301ada8a28d3.json b/src/enm/study-FCSV-d471cef1-160a-3124-97da-301ada8a28d3.json
new file mode 100644
index 0000000..636cf62
--- /dev/null
+++ b/src/enm/study-FCSV-d471cef1-160a-3124-97da-301ada8a28d3.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-d471cef1-160a-3124-97da-301ada8a28d3",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-4026a85b-f254-3d35-bd77-c634d38e4a22"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d4ad6677-83ab-3aba-a2c1-61ef6aba6792.json b/src/enm/study-FCSV-d4ad6677-83ab-3aba-a2c1-61ef6aba6792.json
new file mode 100644
index 0000000..93cf65d
--- /dev/null
+++ b/src/enm/study-FCSV-d4ad6677-83ab-3aba-a2c1-61ef6aba6792.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-d4ad6677-83ab-3aba-a2c1-61ef6aba6792",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-064f1803-3b9e-3f44-a5f6-60b1f573830c"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
+ "loValue": 0.436,
+ "errQualifier": "sd",
+ "errorValue": 0.471
+ }
+ }
+ ]
+}
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+ "endpoint": "ICP-AES",
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d6f87e4e-152e-332e-98dc-66f37af086fa.json b/src/enm/study-FCSV-d6f87e4e-152e-332e-98dc-66f37af086fa.json
new file mode 100644
index 0000000..0d6af99
--- /dev/null
+++ b/src/enm/study-FCSV-d6f87e4e-152e-332e-98dc-66f37af086fa.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-d6f87e4e-152e-332e-98dc-66f37af086fa",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9964d099-d8aa-3a89-863c-d69fc921bee2"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d7038407-4445-3e9a-8d9b-22dfbdd6b998.json b/src/enm/study-FCSV-d7038407-4445-3e9a-8d9b-22dfbdd6b998.json
new file mode 100644
index 0000000..332db78
--- /dev/null
+++ b/src/enm/study-FCSV-d7038407-4445-3e9a-8d9b-22dfbdd6b998.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-d7038407-4445-3e9a-8d9b-22dfbdd6b998",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-edc7f198-f391-328e-aa68-7d3f00b62af5"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d76101c0-f4f9-3f5b-9752-37946b8cc962.json b/src/enm/study-FCSV-d76101c0-f4f9-3f5b-9752-37946b8cc962.json
new file mode 100644
index 0000000..aa73c48
--- /dev/null
+++ b/src/enm/study-FCSV-d76101c0-f4f9-3f5b-9752-37946b8cc962.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-d76101c0-f4f9-3f5b-9752-37946b8cc962",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6405ef25-683e-3763-a4e3-f56eb93174e4"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 239.381,
+ "errQualifier": "sd",
+ "errorValue": 16.632
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
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+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 0.0,
+ "errQualifier": "sem",
+ "errorValue": 0.043
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d8e4d507-da97-340c-9dfd-7af6c346f1f3.json b/src/enm/study-FCSV-d8e4d507-da97-340c-9dfd-7af6c346f1f3.json
new file mode 100644
index 0000000..11b8b41
--- /dev/null
+++ b/src/enm/study-FCSV-d8e4d507-da97-340c-9dfd-7af6c346f1f3.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-d8e4d507-da97-340c-9dfd-7af6c346f1f3",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-06c1d24b-426b-39ec-8047-700808302325"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.05,
+ "errQualifier": "sd",
+ "errorValue": 0.039
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": -4.326,
+ "errQualifier": "std",
+ "errorValue": 1.138
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d9158cde-064f-37e7-a005-176277a768df.json b/src/enm/study-FCSV-d9158cde-064f-37e7-a005-176277a768df.json
new file mode 100644
index 0000000..71e4265
--- /dev/null
+++ b/src/enm/study-FCSV-d9158cde-064f-37e7-a005-176277a768df.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-d9158cde-064f-37e7-a005-176277a768df",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9964d099-d8aa-3a89-863c-d69fc921bee2"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-d9d7b341-b818-3238-9309-960d01b03966.json b/src/enm/study-FCSV-d9d7b341-b818-3238-9309-960d01b03966.json
new file mode 100644
index 0000000..6ed44e2
--- /dev/null
+++ b/src/enm/study-FCSV-d9d7b341-b818-3238-9309-960d01b03966.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-d9d7b341-b818-3238-9309-960d01b03966",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6d5b38c4-f57f-31de-b8b4-2719792f82f2"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.017,
+ "errQualifier": "sd",
+ "errorValue": 0.003
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-dd5498ba-7787-3b4a-b5c3-358f78c7f7dc.json b/src/enm/study-FCSV-dd5498ba-7787-3b4a-b5c3-358f78c7f7dc.json
new file mode 100644
index 0000000..85cc784
--- /dev/null
+++ b/src/enm/study-FCSV-dd5498ba-7787-3b4a-b5c3-358f78c7f7dc.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-dd5498ba-7787-3b4a-b5c3-358f78c7f7dc",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-b38f2b71-aa2d-3d72-af88-166a60bedee2"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.216,
+ "errQualifier": "sd",
+ "errorValue": 0.032
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.197,
+ "errQualifier": "sd",
+ "errorValue": 0.015
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-dd6c41c4-5b7c-3bdf-b0e9-8e15b77b2dce.json b/src/enm/study-FCSV-dd6c41c4-5b7c-3bdf-b0e9-8e15b77b2dce.json
new file mode 100644
index 0000000..576bdb7
--- /dev/null
+++ b/src/enm/study-FCSV-dd6c41c4-5b7c-3bdf-b0e9-8e15b77b2dce.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-dd6c41c4-5b7c-3bdf-b0e9-8e15b77b2dce",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-62d68a47-f27e-3d76-a7cf-5cacae221ec7"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.243,
+ "errQualifier": "sd",
+ "errorValue": 0.028
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": -2.043,
+ "errQualifier": "std",
+ "errorValue": 0.165
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-dd97debf-b900-39c3-9032-57bff884d762.json b/src/enm/study-FCSV-dd97debf-b900-39c3-9032-57bff884d762.json
new file mode 100644
index 0000000..e4ee569
--- /dev/null
+++ b/src/enm/study-FCSV-dd97debf-b900-39c3-9032-57bff884d762.json
@@ -0,0 +1,80 @@
+{
+ "uuid": "FCSV-dd97debf-b900-39c3-9032-57bff884d762",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-3b96ad7a-bf2d-360d-881a-26094f498af6"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "1-Dodecanethiol"
+ }
+ },
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "1,2-dioleoyl-3-trimethylammonium-propane"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-dde1271e-4034-3c9c-88b1-fd9eada86b93.json b/src/enm/study-FCSV-dde1271e-4034-3c9c-88b1-fd9eada86b93.json
new file mode 100644
index 0000000..fdae64b
--- /dev/null
+++ b/src/enm/study-FCSV-dde1271e-4034-3c9c-88b1-fd9eada86b93.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-dde1271e-4034-3c9c-88b1-fd9eada86b93",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-9294730f-3d55-36da-80b9-eb2df162e805"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-de1a44e3-f832-39e6-9e8e-b00f7c6b74fd.json b/src/enm/study-FCSV-de1a44e3-f832-39e6-9e8e-b00f7c6b74fd.json
new file mode 100644
index 0000000..22bb94c
--- /dev/null
+++ b/src/enm/study-FCSV-de1a44e3-f832-39e6-9e8e-b00f7c6b74fd.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-de1a44e3-f832-39e6-9e8e-b00f7c6b74fd",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-4dd1bf89-e885-3128-abe2-9a87fbbd0242"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": " ",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": 22.78,
+ "errQualifier": "sd",
+ "errorValue": 3.88
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "mean",
+ "loValue": -5.43,
+ "errQualifier": "sd",
+ "errorValue": 4.73
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-de678e5c-2a47-3cf6-99ed-3c5e936cfb6a.json b/src/enm/study-FCSV-de678e5c-2a47-3cf6-99ed-3c5e936cfb6a.json
new file mode 100644
index 0000000..3a29c41
--- /dev/null
+++ b/src/enm/study-FCSV-de678e5c-2a47-3cf6-99ed-3c5e936cfb6a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-de678e5c-2a47-3cf6-99ed-3c5e936cfb6a",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ff7e8515-cfad-3d76-a918-d6eeab10a91d"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-dea3be08-75cb-3c10-b445-c906715411b5.json b/src/enm/study-FCSV-dea3be08-75cb-3c10-b445-c906715411b5.json
new file mode 100644
index 0000000..6e01f0d
--- /dev/null
+++ b/src/enm/study-FCSV-dea3be08-75cb-3c10-b445-c906715411b5.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-dea3be08-75cb-3c10-b445-c906715411b5",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-3c5fb4b0-2e4e-3dae-9eb2-1dbfd202cd13"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.01,
+ "errQualifier": "sd",
+ "errorValue": 0.008
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
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index 0000000..e51fafd
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diff --git a/src/enm/study-FCSV-df4b175c-514d-35e0-b592-3e77d5b15c97.json b/src/enm/study-FCSV-df4b175c-514d-35e0-b592-3e77d5b15c97.json
new file mode 100644
index 0000000..2d02edd
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-df54e7ee-8b9d-3562-9043-8a5f05806361.json b/src/enm/study-FCSV-df54e7ee-8b9d-3562-9043-8a5f05806361.json
new file mode 100644
index 0000000..2a857f9
--- /dev/null
+++ b/src/enm/study-FCSV-df54e7ee-8b9d-3562-9043-8a5f05806361.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-df54e7ee-8b9d-3562-9043-8a5f05806361",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-8619e6db-2c01-389e-b05b-e75273d18359"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.7,
+ "errQualifier": "sd",
+ "errorValue": 0.296
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
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diff --git a/src/enm/study-FCSV-e0d66de3-cb23-3b51-b27a-54324d4fb98f.json b/src/enm/study-FCSV-e0d66de3-cb23-3b51-b27a-54324d4fb98f.json
new file mode 100644
index 0000000..f10c5bd
--- /dev/null
+++ b/src/enm/study-FCSV-e0d66de3-cb23-3b51-b27a-54324d4fb98f.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-e0d66de3-cb23-3b51-b27a-54324d4fb98f",
+ "owner": {
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+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
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+ ]
+ },
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+ },
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diff --git a/src/enm/study-FCSV-e0fdf31b-bf9e-3d9a-970f-1fb13ed9b963.json b/src/enm/study-FCSV-e0fdf31b-bf9e-3d9a-970f-1fb13ed9b963.json
new file mode 100644
index 0000000..f3be6b9
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+++ b/src/enm/study-FCSV-e0fdf31b-bf9e-3d9a-970f-1fb13ed9b963.json
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+{
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
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+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
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+ "endpoint": "Ellman depletion assay",
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+ ]
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+ {
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diff --git a/src/enm/study-FCSV-e10ee022-607a-3de1-a09f-27b86e2c965c.json b/src/enm/study-FCSV-e10ee022-607a-3de1-a09f-27b86e2c965c.json
new file mode 100644
index 0000000..6e3433b
--- /dev/null
+++ b/src/enm/study-FCSV-e10ee022-607a-3de1-a09f-27b86e2c965c.json
@@ -0,0 +1,77 @@
+{
+ "uuid": "FCSV-e10ee022-607a-3de1-a09f-27b86e2c965c",
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+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
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+ "year": "2014",
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+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "DLS",
+ "guideline": [
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+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
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diff --git a/src/enm/study-FCSV-e139a372-bb63-32da-bb83-6f6aa453c3d8.json b/src/enm/study-FCSV-e139a372-bb63-32da-bb83-6f6aa453c3d8.json
new file mode 100644
index 0000000..6c181e4
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+{
+ "uuid": "FCSV-e139a372-bb63-32da-bb83-6f6aa453c3d8",
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
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+ },
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+ "code": "PROTEOMICS_SECTION",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e163d83f-1d6e-3b22-95b1-15f94c23f4aa.json b/src/enm/study-FCSV-e163d83f-1d6e-3b22-95b1-15f94c23f4aa.json
new file mode 100644
index 0000000..632af48
--- /dev/null
+++ b/src/enm/study-FCSV-e163d83f-1d6e-3b22-95b1-15f94c23f4aa.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-e163d83f-1d6e-3b22-95b1-15f94c23f4aa",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-2de5071e-596b-3507-84fc-f9ba470cbcbf"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 14.9,
+ "errQualifier": "sd",
+ "errorValue": 1.2
+ }
+ },
+ {
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+ "errQualifier": "sd",
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+ }
+ },
+ {
+ "endpoint": "LSPR peak position (nm)",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 542,
+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e30c1169-808c-3bad-a229-875911f8ad16.json b/src/enm/study-FCSV-e30c1169-808c-3bad-a229-875911f8ad16.json
new file mode 100644
index 0000000..738b987
--- /dev/null
+++ b/src/enm/study-FCSV-e30c1169-808c-3bad-a229-875911f8ad16.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "FCSV-e30c1169-808c-3bad-a229-875911f8ad16",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-7ad8c003-d0ee-3ea6-9374-b6e4d2f33401"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Bicinchoninic Acid (BCA) Assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Total protein (BCA assay)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug",
+ "loQualifier": "mean",
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+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e326ad5a-c2f7-38be-8130-5de15d3f6699.json b/src/enm/study-FCSV-e326ad5a-c2f7-38be-8130-5de15d3f6699.json
new file mode 100644
index 0000000..19a76e6
--- /dev/null
+++ b/src/enm/study-FCSV-e326ad5a-c2f7-38be-8130-5de15d3f6699.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-e326ad5a-c2f7-38be-8130-5de15d3f6699",
+ "owner": {
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+ "uuid": "FCSV-8b5b62c3-7fd2-3bba-b293-b7537e4971b1"
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+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
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+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "loValue": 75.37,
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+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
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+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
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+ },
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+ "loQualifier": "mean",
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+ "Remark": null,
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+ "endpoint": "Number Mean Hydrodynamic Diameter",
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+ },
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+ {
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+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
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+ },
+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
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+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
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+ },
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+ "loValue": 95.2,
+ "errQualifier": "sd",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e339ae7e-feaf-30ab-8214-af9adb52e835.json b/src/enm/study-FCSV-e339ae7e-feaf-30ab-8214-af9adb52e835.json
new file mode 100644
index 0000000..2ada738
--- /dev/null
+++ b/src/enm/study-FCSV-e339ae7e-feaf-30ab-8214-af9adb52e835.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-e339ae7e-feaf-30ab-8214-af9adb52e835",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6b272721-ed04-31bd-a4d4-cb6496140e85"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
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+ },
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+ },
+ "effects": [
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+ "endpoint": "ATOMIC COMPOSITION",
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e34eb9a1-fc40-3126-b05b-c88d9ea0b7d2.json b/src/enm/study-FCSV-e34eb9a1-fc40-3126-b05b-c88d9ea0b7d2.json
new file mode 100644
index 0000000..5136641
--- /dev/null
+++ b/src/enm/study-FCSV-e34eb9a1-fc40-3126-b05b-c88d9ea0b7d2.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-e34eb9a1-fc40-3126-b05b-c88d9ea0b7d2",
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
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+ },
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+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e35304f2-bab5-307c-a2b7-3526a1c01213.json b/src/enm/study-FCSV-e35304f2-bab5-307c-a2b7-3526a1c01213.json
new file mode 100644
index 0000000..3b760c5
--- /dev/null
+++ b/src/enm/study-FCSV-e35304f2-bab5-307c-a2b7-3526a1c01213.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-e35304f2-bab5-307c-a2b7-3526a1c01213",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ed95bb69-9fa7-3a4a-b4a4-32dd947d4d1a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.25,
+ "errQualifier": "sd",
+ "errorValue": 0.059
+ }
+ },
+ {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e5b47b68-6418-3d77-9262-b2c83423985d.json b/src/enm/study-FCSV-e5b47b68-6418-3d77-9262-b2c83423985d.json
new file mode 100644
index 0000000..77b4ba5
--- /dev/null
+++ b/src/enm/study-FCSV-e5b47b68-6418-3d77-9262-b2c83423985d.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-e5b47b68-6418-3d77-9262-b2c83423985d",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-5c14595c-0e23-3f37-aaad-9988eba09196"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "FUNCTIONAL GROUP",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "FUNCTIONALIZATION"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Thiolated L-threonine"
+ }
+ }
+ ]
+}
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+{
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index 0000000..efd4d87
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+{
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diff --git a/src/enm/study-FCSV-e81d3b28-8a8e-372b-9b53-9196ea67df2f.json b/src/enm/study-FCSV-e81d3b28-8a8e-372b-9b53-9196ea67df2f.json
new file mode 100644
index 0000000..f46bd21
--- /dev/null
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+{
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e832825b-13bd-3480-a703-20f468c2a4c4.json b/src/enm/study-FCSV-e832825b-13bd-3480-a703-20f468c2a4c4.json
new file mode 100644
index 0000000..5925527
--- /dev/null
+++ b/src/enm/study-FCSV-e832825b-13bd-3480-a703-20f468c2a4c4.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-e832825b-13bd-3480-a703-20f468c2a4c4",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-7c56798c-f7cd-37d3-8a67-ead57f36db31"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e85722df-5306-36c4-8574-35d4cbd566a5.json b/src/enm/study-FCSV-e85722df-5306-36c4-8574-35d4cbd566a5.json
new file mode 100644
index 0000000..93d48b3
--- /dev/null
+++ b/src/enm/study-FCSV-e85722df-5306-36c4-8574-35d4cbd566a5.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-e85722df-5306-36c4-8574-35d4cbd566a5",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-6d5b38c4-f57f-31de-b8b4-2719792f82f2"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 213.324,
+ "errQualifier": "sd",
+ "errorValue": 4.554
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
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+ {
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+ {
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+ },
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+ },
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e98a0914-318b-3a36-996b-dd2dff1dc911.json b/src/enm/study-FCSV-e98a0914-318b-3a36-996b-dd2dff1dc911.json
new file mode 100644
index 0000000..8991196
--- /dev/null
+++ b/src/enm/study-FCSV-e98a0914-318b-3a36-996b-dd2dff1dc911.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-e98a0914-318b-3a36-996b-dd2dff1dc911",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-70406142-0fd6-30bd-873b-5cce39016ed5"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 59.3,
+ "errQualifier": "sd",
+ "errorValue": 6.4
+ }
+ },
+ {
+ "endpoint": "Density",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/cm^3",
+ "loQualifier": "",
+ "loValue": 19.1
+ }
+ },
+ {
+ "endpoint": "MW",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "g/mol",
+ "loQualifier": "",
+ "loValue": 197
+ }
+ },
+ {
+ "endpoint": "Mol/NP",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "",
+ "loValue": 0.0
+ }
+ },
+ {
+ "endpoint": "SA/NP",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "cm^2/NP",
+ "loQualifier": "",
+ "loValue": 0.0
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-e9c24201-2e88-31b2-81b5-b6b352493777.json b/src/enm/study-FCSV-e9c24201-2e88-31b2-81b5-b6b352493777.json
new file mode 100644
index 0000000..61ad395
--- /dev/null
+++ b/src/enm/study-FCSV-e9c24201-2e88-31b2-81b5-b6b352493777.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-e9c24201-2e88-31b2-81b5-b6b352493777",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-4dd1bf89-e885-3128-abe2-9a87fbbd0242"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-ea0d9762-d05d-3e13-95bd-b2ff3f376679.json b/src/enm/study-FCSV-ea0d9762-d05d-3e13-95bd-b2ff3f376679.json
new file mode 100644
index 0000000..7ecb0ce
--- /dev/null
+++ b/src/enm/study-FCSV-ea0d9762-d05d-3e13-95bd-b2ff3f376679.json
@@ -0,0 +1,86 @@
+{
+ "uuid": "FCSV-ea0d9762-d05d-3e13-95bd-b2ff3f376679",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-cd7105f2-f630-360e-b8dc-ff42b18bb421"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Absorbance.spectrophotometry.AS.",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "UV-1601PC absorbance spectrophotometer (Shimadzu)",
+ "Type of method": "Absorbance.spectrophotometry.AS.",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
+ "loValue": 0.396,
+ "errQualifier": "sd",
+ "errorValue": 0.108
+ }
+ },
+ {
+ "endpoint": "Localized Surface Plasmon Resonance (LSPR) index",
+ "conditions": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-f065d547-ff21-3c10-b507-d37143c230c4.json b/src/enm/study-FCSV-f065d547-ff21-3c10-b507-d37143c230c4.json
new file mode 100644
index 0000000..312cbd1
--- /dev/null
+++ b/src/enm/study-FCSV-f065d547-ff21-3c10-b507-d37143c230c4.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-f065d547-ff21-3c10-b507-d37143c230c4",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-b228fc7b-c407-368a-bc1c-359c7375bb9b"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "CRYSTALLITE_AND_GRAIN_SIZE_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.26 Nanomaterial crystallite and grain size"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": " "
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 0.106,
+ "errQualifier": "sd",
+ "errorValue": 0.007
+ }
+ },
+ {
+ "endpoint": "Polydispersity index",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-f1fb7819-16e8-3c90-a7f3-d1a6bcd0ba37.json b/src/enm/study-FCSV-f1fb7819-16e8-3c90-a7f3-d1a6bcd0ba37.json
new file mode 100644
index 0000000..70a998f
--- /dev/null
+++ b/src/enm/study-FCSV-f1fb7819-16e8-3c90-a7f3-d1a6bcd0ba37.json
@@ -0,0 +1,85 @@
+{
+ "uuid": "FCSV-f1fb7819-16e8-3c90-a7f3-d1a6bcd0ba37",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-a153cba3-a82d-3e3c-bcbd-335cc5155f44"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_UNKNOWN_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.99 Physico chemical properties (other)"
+ },
+ "endpoint": "Ellman depletion assay",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "Type of method": "Serum.density",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Autot (ICP-AES)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "nmol",
+ "loQualifier": "mean",
+ "loValue": 268.117,
+ "errQualifier": "sd",
+ "errorValue": 2.341
+ }
+ },
+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 11,
+ "errQualifier": "sd",
+ "errorValue": 0.0
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 1,
+ "errQualifier": "sem",
+ "errorValue": 0.05
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-f283b181-a562-3cd5-b56e-d468ea6c007f.json b/src/enm/study-FCSV-f283b181-a562-3cd5-b56e-d468ea6c007f.json
new file mode 100644
index 0000000..b740b85
--- /dev/null
+++ b/src/enm/study-FCSV-f283b181-a562-3cd5-b56e-d468ea6c007f.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-f283b181-a562-3cd5-b56e-d468ea6c007f",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-07ecc16e-528e-3904-bb96-0812dff8ea65"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Ag]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-f2d1d273-db93-3e6a-8026-96b5379831a0.json b/src/enm/study-FCSV-f2d1d273-db93-3e6a-8026-96b5379831a0.json
new file mode 100644
index 0000000..9accdf2
--- /dev/null
+++ b/src/enm/study-FCSV-f2d1d273-db93-3e6a-8026-96b5379831a0.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-f2d1d273-db93-3e6a-8026-96b5379831a0",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-ccd3915e-0b1d-38f4-98b3-02b1a16aace7"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "PROTEOMICS_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "8.100 Proteomics"
+ },
+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
+ "Type of method": "LC MS/MS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Spectral counts",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "textValue": 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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-f358d269-7746-371c-9339-2fd233e014b2.json b/src/enm/study-FCSV-f358d269-7746-371c-9339-2fd233e014b2.json
new file mode 100644
index 0000000..a5d2996
--- /dev/null
+++ b/src/enm/study-FCSV-f358d269-7746-371c-9339-2fd233e014b2.json
@@ -0,0 +1,114 @@
+{
+ "uuid": "FCSV-f358d269-7746-371c-9339-2fd233e014b2",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-acbbde2e-0238-3d4c-a2f4-7629ad478e6a"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "TEM",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Tecnai 20 (FEI) microscope;Tecnai 20 (FEI) microscope;AMT 16000 camera",
+ "Type of method": "TEM",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Core size",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 59.3,
+ "errQualifier": "sd",
+ "errorValue": 6.4
+ }
+ },
+ {
+ "endpoint": "Density",
+ "conditions": {
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+ {
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+ {
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+ {
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+ }
+ }
+ ]
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diff --git a/src/enm/study-FCSV-f5d6422c-d681-3567-ba37-8d2d0aff732d.json b/src/enm/study-FCSV-f5d6422c-d681-3567-ba37-8d2d0aff732d.json
new file mode 100644
index 0000000..3699329
--- /dev/null
+++ b/src/enm/study-FCSV-f5d6422c-d681-3567-ba37-8d2d0aff732d.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-f5d6422c-d681-3567-ba37-8d2d0aff732d",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-31bd6c7b-3247-3db9-93b6-59e0d3ecefa9"
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+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
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+ "testmat_form": null
+ },
+ "reliability": {
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+ "r_studyResultType": "experimental result",
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+ },
+ "effects": [
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+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Ag]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-f5d79ce0-419d-3157-9b4d-0fe063f383ad.json b/src/enm/study-FCSV-f5d79ce0-419d-3157-9b4d-0fe063f383ad.json
new file mode 100644
index 0000000..502df6f
--- /dev/null
+++ b/src/enm/study-FCSV-f5d79ce0-419d-3157-9b4d-0fe063f383ad.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-f5d79ce0-419d-3157-9b4d-0fe063f383ad",
+ "owner": {
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+ "uuid": "FCSV-0542c513-7015-3169-a1c1-e00f811a7ba0"
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+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
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+ "textValue": "[Au]"
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diff --git a/src/enm/study-FCSV-f62472d9-41a4-3392-9760-109961cbda7f.json b/src/enm/study-FCSV-f62472d9-41a4-3392-9760-109961cbda7f.json
new file mode 100644
index 0000000..263b0a1
--- /dev/null
+++ b/src/enm/study-FCSV-f62472d9-41a4-3392-9760-109961cbda7f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "FCSV-f62472d9-41a4-3392-9760-109961cbda7f",
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+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
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+ "code": "PROTEOMICS_SECTION",
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+ "title": "8.100 Proteomics"
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+ "endpoint": "Solution-based digestion protocol for serum protein isolates",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Orbitrap-Velos mass spectrometer (Thermo)",
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+ "effects": [
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+ "endpoint": "Spectral counts",
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+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-f6949345-efac-3430-b4fe-92a64f8eb885.json b/src/enm/study-FCSV-f6949345-efac-3430-b4fe-92a64f8eb885.json
new file mode 100644
index 0000000..35cf6e6
--- /dev/null
+++ b/src/enm/study-FCSV-f6949345-efac-3430-b4fe-92a64f8eb885.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "FCSV-f6949345-efac-3430-b4fe-92a64f8eb885",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-b38f2b71-aa2d-3d72-af88-166a60bedee2"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "ICP-AES",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "Perkin-Elmer",
+ "Type of method": "ICP-AES",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Net cell association",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "mL/ug(Mg)",
+ "loQualifier": "mean",
+ "loValue": 0.024,
+ "errQualifier": "sd",
+ "errorValue": 0.012
+ }
+ },
+ {
+ "endpoint": "Log2 transformed",
+ "conditions": {
+ "Cell": "A549"
+ },
+ "result": {
+ "unit": "",
+ "loQualifier": "mean",
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+ {
+ "endpoint": "Total surface area (SAtot)",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "cm^2",
+ "loQualifier": "mean",
+ "loValue": 10,
+ "errQualifier": "sd",
+ "errorValue": 1
+ }
+ },
+ {
+ "endpoint": "Protein density",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)"
+ },
+ "result": {
+ "unit": "ug/cm^2",
+ "loQualifier": "mean",
+ "loValue": 1,
+ "errQualifier": "sem",
+ "errorValue": 0.049
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-ff7c5306-71cd-383e-aacd-96d251f34d0b.json b/src/enm/study-FCSV-ff7c5306-71cd-383e-aacd-96d251f34d0b.json
new file mode 100644
index 0000000..64bdc3a
--- /dev/null
+++ b/src/enm/study-FCSV-ff7c5306-71cd-383e-aacd-96d251f34d0b.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "FCSV-ff7c5306-71cd-383e-aacd-96d251f34d0b",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-5b29295c-f2ab-3e5a-bb32-37caac38b002"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Description",
+ "guideline": [
+ "Description"
+ ]
+ },
+ "parameters": {
+ "Type of method": null,
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": null,
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "[Au]"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-FCSV-ff92640c-4229-35e3-aede-d7a8f36ee365.json b/src/enm/study-FCSV-ff92640c-4229-35e3-aede-d7a8f36ee365.json
new file mode 100644
index 0000000..75e4c25
--- /dev/null
+++ b/src/enm/study-FCSV-ff92640c-4229-35e3-aede-d7a8f36ee365.json
@@ -0,0 +1,169 @@
+{
+ "uuid": "FCSV-ff92640c-4229-35e3-aede-d7a8f36ee365",
+ "owner": {
+ "substance": {
+ "uuid": "FCSV-bc77c03d-4e75-3fab-bb3d-17b983663819"
+ },
+ "company": {
+ "uuid": "FCSV-319611c6-e7da-3977-a5ac-eb74d49a4319",
+ "name": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv"
+ }
+ },
+ "citation": {
+ "title": "Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.csv",
+ "year": "2014",
+ "owner": null
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "DLS",
+ "guideline": [
+ "doi: 10.1021/nn406018q"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": "ZetaSizer Nano ZS (Malvern Instruments)",
+ "Type of method": "DLS",
+ "testmat_form": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 22.36,
+ "errQualifier": "sd",
+ "errorValue": 0.94
+ }
+ },
+ {
+ "endpoint": "Z-Average Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "mean",
+ "loValue": 57.53,
+ "errQualifier": "sd",
+ "errorValue": 2.05
+ }
+ },
+ {
+ "endpoint": "Volume Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 21.94,
+ "errQualifier": "sd",
+ "errorValue": 0.08
+ }
+ },
+ {
+ "endpoint": "Volume Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 21.75,
+ "errQualifier": "sd",
+ "errorValue": 17.23
+ }
+ },
+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 23.49,
+ "errQualifier": "sd",
+ "errorValue": 0.48
+ }
+ },
+ {
+ "endpoint": "Number Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 18.38,
+ "errQualifier": "sd",
+ "errorValue": 14.53
+ }
+ },
+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": " ",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 23.49,
+ "errQualifier": "sd",
+ "errorValue": 0.75
+ }
+ },
+ {
+ "endpoint": "Intensity Mean Hydrodynamic Diameter",
+ "conditions": {
+ "MEDIUM": "Human serum (Sigma #H4522)",
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 70.97,
+ "errQualifier": "sd",
+ "errorValue": 7.26
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-IUC5-49179f2f-867c-4e7c-8fd1-d09eb23c4c3d.json b/src/enm/study-IUC5-49179f2f-867c-4e7c-8fd1-d09eb23c4c3d.json
new file mode 100644
index 0000000..9285fed
--- /dev/null
+++ b/src/enm/study-IUC5-49179f2f-867c-4e7c-8fd1-d09eb23c4c3d.json
@@ -0,0 +1,68 @@
+{
+ "uuid": "IUC5-49179f2f-867c-4e7c-8fd1-d09eb23c4c3d",
+ "owner": {
+ "substance": {
+ "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
+ },
+ "company": {
+ "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
+ "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "2006",
+ "owner": ""
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "TO_ACUTE_ORAL_SECTION",
+ "term": "http://purl.enanomapper.org/onto/ENM_0000020",
+ "title": "7.2.1 Acute toxicity - oral"
+ },
+ "endpoint": "Acute toxicity: oral.001",
+ "guideline": [
+ "OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)"
+ ]
+ },
+ "parameters": {
+ "Sex": "female",
+ "Species": "rat"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": "key study",
+ "r_studyResultType": "experimental result",
+ "r_value": "1 (reliable without restriction)"
+ },
+ "interpretation": {
+ "result": "practically nontoxic"
+ },
+ "effects": [
+ {
+ "endpoint": "LDLo",
+ "conditions": {
+ "Sex": "female"
+ },
+ "result": {
+ "unit": "mg/kg bw",
+ "loQualifier": ">=",
+ "loValue": 2000
+ }
+ },
+ {
+ "endpoint": "LD50 cut-off ",
+ "conditions": {
+ "Sex": "female"
+ },
+ "result": {
+ "unit": "mg/kg bw",
+ "loQualifier": ">=",
+ "loValue": 5000
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-IUC5-4bca14fc-3e43-435e-a06e-d924fc77bded.json b/src/enm/study-IUC5-4bca14fc-3e43-435e-a06e-d924fc77bded.json
new file mode 100644
index 0000000..edea576
--- /dev/null
+++ b/src/enm/study-IUC5-4bca14fc-3e43-435e-a06e-d924fc77bded.json
@@ -0,0 +1,115 @@
+{
+ "uuid": "IUC5-4bca14fc-3e43-435e-a06e-d924fc77bded",
+ "owner": {
+ "substance": {
+ "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
+ },
+ "company": {
+ "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
+ "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "2011",
+ "owner": ""
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle size distribution (Granulometry).001",
+ "guideline": [
+ "Transmission Electron Microscopy (TEM)"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": "imaging technique",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": "key study",
+ "r_studyResultType": "experimental result",
+ "r_value": "2 (reliable with restrictions)"
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN DIAMETER",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": {
+ "loValue": null
+ },
+ "SEQ_NUM": {
+ "loValue": null
+ },
+ "STD_DEV": {
+ "loValue": null
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 3,
+ "upQualifier": "<",
+ "upValue": 20
+ }
+ },
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": null,
+ "Remark": {
+ "loValue": null
+ },
+ "SEQ_NUM": {
+ "loValue": null
+ },
+ "STD_DEV": {
+ "Class": "GEOMETRIC STANDARD DEVIATION",
+ "isResult": "true",
+ "loQualifier": null,
+ "loValue": null,
+ "upQualifier": null
+ }
+ },
+ "result": {
+ "unit": null
+ }
+ },
+ {
+ "endpoint": "PARTICLE SIZE.D90",
+ "conditions": {
+ "PHRASEOTHER_PERCENTILE": {
+ "loQualifier": " ",
+ "loValue": "D90"
+ },
+ "Remark": {
+ "loValue": null
+ },
+ "SEQ_NUM": {
+ "loValue": null
+ },
+ "STD_DEV": {
+ "loValue": null
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": "",
+ "loValue": 12.7,
+ "upQualifier": "",
+ "textValue": ""
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-IUC5-4d6e67a8-4301-4e6a-bafc-20e20fbaf2ad.json b/src/enm/study-IUC5-4d6e67a8-4301-4e6a-bafc-20e20fbaf2ad.json
new file mode 100644
index 0000000..5f17930
--- /dev/null
+++ b/src/enm/study-IUC5-4d6e67a8-4301-4e6a-bafc-20e20fbaf2ad.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "IUC5-4d6e67a8-4301-4e6a-bafc-20e20fbaf2ad",
+ "owner": {
+ "substance": {
+ "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
+ },
+ "company": {
+ "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
+ "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "2006",
+ "owner": ""
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific surface area.001",
+ "guideline": [
+ "DIN66131"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": "BET"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": "key study",
+ "r_studyResultType": "experimental result",
+ "r_value": "2 (reliable with restrictions)"
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null,
+ "STD_DEV": {
+ }
+ },
+ "result": {
+ "unit": "m²/g",
+ "loQualifier": "",
+ "loValue": 253,
+ "upQualifier": ""
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-IUC5-6bdaad41-66c2-4d24-99ee-8d579243ddd9.json b/src/enm/study-IUC5-6bdaad41-66c2-4d24-99ee-8d579243ddd9.json
new file mode 100644
index 0000000..c2d07ab
--- /dev/null
+++ b/src/enm/study-IUC5-6bdaad41-66c2-4d24-99ee-8d579243ddd9.json
@@ -0,0 +1,71 @@
+{
+ "uuid": "IUC5-6bdaad41-66c2-4d24-99ee-8d579243ddd9",
+ "owner": {
+ "substance": {
+ "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
+ },
+ "company": {
+ "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
+ "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
+ }
+ },
+ "citation": {
+ "title": "Thurnherr, T. et al.",
+ "year": "2011",
+ "owner": ""
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "TO_GENETIC_IN_VITRO_SECTION",
+ "term": "http://www.bioassayontology.org/bao#BAO_0002167",
+ "title": "7.6.1 Genetic toxicity in vitro"
+ },
+ "endpoint": "Exp Supporting Genetic toxicity in vitro.008",
+ "guideline": [
+ null
+ ]
+ },
+ "parameters": {
+ "Metabolic activation system": null,
+ "Species": "human pulmonary epithelial cell line A549",
+ "Target gene": null,
+ "Type of genotoxicity": "chromosome and DNA damage",
+ "Type of study": "Micronucleus test in vitro (MNvit) and Comet assay in vitro"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": "supporting study",
+ "r_studyResultType": "experimental result",
+ "r_value": "other:"
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "GENOTOXICITY",
+ "conditions": {
+ "Metabolic activation": "without",
+ "Species": "A549"
+ },
+ "result": {
+ "unit": null,
+ "textValue": "negative"
+ }
+ },
+ {
+ "endpoint": "GENOTOXICITY",
+ "conditions": {
+ "Metabolic activation": "without",
+ "Species": "A549"
+ },
+ "result": {
+ "unit": null,
+ "textValue": "negative"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-IUC5-708684e4-4e3b-49cd-92ec-9fc2f3a4dc14.json b/src/enm/study-IUC5-708684e4-4e3b-49cd-92ec-9fc2f3a4dc14.json
new file mode 100644
index 0000000..b8de91e
--- /dev/null
+++ b/src/enm/study-IUC5-708684e4-4e3b-49cd-92ec-9fc2f3a4dc14.json
@@ -0,0 +1,129 @@
+{
+ "uuid": "IUC5-708684e4-4e3b-49cd-92ec-9fc2f3a4dc14",
+ "owner": {
+ "substance": {
+ "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
+ },
+ "company": {
+ "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
+ "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "2010",
+ "owner": ""
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta potential.001",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": "key study",
+ "r_studyResultType": "experimental result",
+ "r_value": "2 (reliable with restrictions)"
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "STD_DEV": {
+ "loValue": 2.9,
+ "unit": ""
+ },
+ "pH": {
+ "loValue": "1.9"
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "",
+ "loValue": 41.4,
+ "upQualifier": ""
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "STD_DEV": {
+ "loValue": 1.5,
+ "unit": ""
+ },
+ "pH": {
+ "loValue": "2.99"
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "",
+ "loValue": 39.3,
+ "upQualifier": ""
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "STD_DEV": {
+ "loValue": 6.5,
+ "unit": ""
+ },
+ "pH": {
+ "loValue": "4.26"
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "",
+ "loValue": 21.4,
+ "upQualifier": ""
+ }
+ },
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "STD_DEV": {
+ "loValue": 1.7,
+ "unit": ""
+ },
+ "pH": {
+ "loValue": "5.04"
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loQualifier": "",
+ "loValue": 34.5,
+ "upQualifier": ""
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-IUC5-74e91cde-2ffa-43ec-8fcd-5d6407f1602c.json b/src/enm/study-IUC5-74e91cde-2ffa-43ec-8fcd-5d6407f1602c.json
new file mode 100644
index 0000000..ec4e227
--- /dev/null
+++ b/src/enm/study-IUC5-74e91cde-2ffa-43ec-8fcd-5d6407f1602c.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "IUC5-74e91cde-2ffa-43ec-8fcd-5d6407f1602c",
+ "owner": {
+ "substance": {
+ "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
+ },
+ "company": {
+ "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
+ "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "2008",
+ "owner": ""
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "DUSTINESS_SECTION",
+ "term": "http://purl.enanomapper.org/onto/ENM_9000003",
+ "title": "4.31 Nanomaterial dustiness"
+ },
+ "endpoint": "Dustiness.001",
+ "guideline": [
+ "DIN 33897-2 (2002) Workplace atmospheres - Determination of the dustiness of bulk materials - Part 2:Continuous Drop (note: SUPERSEDED by EN 1505:2006)"
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": "continuous drop"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": "key study",
+ "r_studyResultType": "experimental result",
+ "r_value": ""
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DUSTINESS INDEX",
+ "conditions": {
+ "STD_DEV": {
+ }
+ },
+ "result": {
+ "unit": null
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-IUC5-9db5f020-e0fa-47c8-8e61-3eeb8038e279.json b/src/enm/study-IUC5-9db5f020-e0fa-47c8-8e61-3eeb8038e279.json
new file mode 100644
index 0000000..1523c0d
--- /dev/null
+++ b/src/enm/study-IUC5-9db5f020-e0fa-47c8-8e61-3eeb8038e279.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "IUC5-9db5f020-e0fa-47c8-8e61-3eeb8038e279",
+ "owner": {
+ "substance": {
+ "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
+ },
+ "company": {
+ "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
+ "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
+ }
+ },
+ "citation": {
+ "title": "Ragot J, Voetz M ",
+ "year": "2010",
+ "owner": ""
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "GI_GENERAL_INFORM_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.1 Appearance"
+ },
+ "endpoint": "Appearance/physical state/colour.001",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": "key study",
+ "r_studyResultType": "experimental result",
+ "r_value": "2 (reliable with restrictions)"
+ },
+ "interpretation": {
+ "result": "inorganic"
+ },
+ "effects": [
+ {
+ "endpoint": "solid",
+ "conditions": {
+ "Remark": "nanomaterial"
+ },
+ "result": {
+ "unit": null
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-IUC5-f6eb018b-2dc5-462b-be29-a6ffce0fd4d4.json b/src/enm/study-IUC5-f6eb018b-2dc5-462b-be29-a6ffce0fd4d4.json
new file mode 100644
index 0000000..b393b4d
--- /dev/null
+++ b/src/enm/study-IUC5-f6eb018b-2dc5-462b-be29-a6ffce0fd4d4.json
@@ -0,0 +1,54 @@
+{
+ "uuid": "IUC5-f6eb018b-2dc5-462b-be29-a6ffce0fd4d4",
+ "owner": {
+ "substance": {
+ "uuid": "IUC5-5f313d1f-4129-499c-abbe-ac18642e2471"
+ },
+ "company": {
+ "uuid": "IUC5-354430c7-746e-450e-9722-09788eb90a29",
+ "name": "Ideaconsult Ltd. / Sofia / Bulgaria"
+ }
+ },
+ "citation": {
+ "title": "Muller, J. et al.",
+ "year": "2009",
+ "owner": ""
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "TO_CARCINOGENICITY_SECTION",
+ "term": "http://purl.enanomapper.org/onto/ENM_0000029",
+ "title": "7.7 Carcinogenicity"
+ },
+ "endpoint": "Carcinogenicity.001",
+ "guideline": [
+ null
+ ]
+ },
+ "parameters": {
+ "Doses/concentrations": "MWCNT+: 2 or 20 mg/animal;MWCNT-: 20 mg/animal;Crocidolite: 2 mg/animal",
+ "Route of administration": "intraperitoneal",
+ "Species": "rat"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": "key study",
+ "r_studyResultType": "experimental result",
+ "r_value": "2 (reliable with restrictions)"
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "",
+ "conditions": {
+ },
+ "result": {
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-001eeffd-a257-4e01-9f59-cd7e4585bc43.json b/src/enm/study-NWKI-001eeffd-a257-4e01-9f59-cd7e4585bc43.json
new file mode 100644
index 0000000..b575ad9
--- /dev/null
+++ b/src/enm/study-NWKI-001eeffd-a257-4e01-9f59-cd7e4585bc43.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-001eeffd-a257-4e01-9f59-cd7e4585bc43",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-90869553-c8fe-3ef6-8e68-47f392958127"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 3.09
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0068416d-360e-4569-8529-b81e33d7879f.json b/src/enm/study-NWKI-0068416d-360e-4569-8529-b81e33d7879f.json
new file mode 100644
index 0000000..73d3608
--- /dev/null
+++ b/src/enm/study-NWKI-0068416d-360e-4569-8529-b81e33d7879f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-0068416d-360e-4569-8529-b81e33d7879f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3481f716-18fa-39b3-aa54-4acb67877194"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 38
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-01254983-14c9-4ff4-a6ab-8a88470c4dc7.json b/src/enm/study-NWKI-01254983-14c9-4ff4-a6ab-8a88470c4dc7.json
new file mode 100644
index 0000000..3ac12b6
--- /dev/null
+++ b/src/enm/study-NWKI-01254983-14c9-4ff4-a6ab-8a88470c4dc7.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-01254983-14c9-4ff4-a6ab-8a88470c4dc7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8667bfb7-a5da-3eb0-b9d7-86e2c8f06f19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 96
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-01266bd1-a36a-47d2-bab4-a3fc99f296d4.json b/src/enm/study-NWKI-01266bd1-a36a-47d2-bab4-a3fc99f296d4.json
new file mode 100644
index 0000000..0d8b8ec
--- /dev/null
+++ b/src/enm/study-NWKI-01266bd1-a36a-47d2-bab4-a3fc99f296d4.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-01266bd1-a36a-47d2-bab4-a3fc99f296d4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-13b28611-c05b-325b-9e60-182c49b2a288"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 1,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 18
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-01486dcf-1529-4177-87cc-3ac2968d7604.json b/src/enm/study-NWKI-01486dcf-1529-4177-87cc-3ac2968d7604.json
new file mode 100644
index 0000000..0231609
--- /dev/null
+++ b/src/enm/study-NWKI-01486dcf-1529-4177-87cc-3ac2968d7604.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-01486dcf-1529-4177-87cc-3ac2968d7604",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-74c6a1ca-f415-3c86-9437-446299eb5e40"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -40.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-01a7905b-d076-404a-b426-406c5eab5b7c.json b/src/enm/study-NWKI-01a7905b-d076-404a-b426-406c5eab5b7c.json
new file mode 100644
index 0000000..6b329c7
--- /dev/null
+++ b/src/enm/study-NWKI-01a7905b-d076-404a-b426-406c5eab5b7c.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-01a7905b-d076-404a-b426-406c5eab5b7c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0d776d00-aec4-3a75-9eb3-453909fc50ed"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "ArabinoGalactanCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Arabino_Galactan"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Arabino_Galactan"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-01ce05e5-80aa-4d3f-84cb-44039ca74d22.json b/src/enm/study-NWKI-01ce05e5-80aa-4d3f-84cb-44039ca74d22.json
new file mode 100644
index 0000000..b823f97
--- /dev/null
+++ b/src/enm/study-NWKI-01ce05e5-80aa-4d3f-84cb-44039ca74d22.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-01ce05e5-80aa-4d3f-84cb-44039ca74d22",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-37a99dad-2a53-3076-b21f-d078b89fb4fb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SiO2"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "SiO2"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "APS_Coating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "APS"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "APS"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-02115f25-e680-41b1-b509-91a9aa73033f.json b/src/enm/study-NWKI-02115f25-e680-41b1-b509-91a9aa73033f.json
new file mode 100644
index 0000000..816c6ae
--- /dev/null
+++ b/src/enm/study-NWKI-02115f25-e680-41b1-b509-91a9aa73033f.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-02115f25-e680-41b1-b509-91a9aa73033f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b8a44a2-b835-3f75-903c-cf0a71a247c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+ "TESTMAT_FORM": null
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+ "loValue": 40,
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+}
diff --git a/src/enm/study-NWKI-0225a419-5e74-4fa8-8939-a2cf688547c9.json b/src/enm/study-NWKI-0225a419-5e74-4fa8-8939-a2cf688547c9.json
new file mode 100644
index 0000000..492c535
--- /dev/null
+++ b/src/enm/study-NWKI-0225a419-5e74-4fa8-8939-a2cf688547c9.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-0225a419-5e74-4fa8-8939-a2cf688547c9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d52e3489-851d-3eeb-b887-9a595cc9adfe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "ZETA POTENTIAL",
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+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
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+ "loValue": -66.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-02443f5b-63fc-40d4-82a7-d8fb8705d72e.json b/src/enm/study-NWKI-02443f5b-63fc-40d4-82a7-d8fb8705d72e.json
new file mode 100644
index 0000000..1a69680
--- /dev/null
+++ b/src/enm/study-NWKI-02443f5b-63fc-40d4-82a7-d8fb8705d72e.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-02443f5b-63fc-40d4-82a7-d8fb8705d72e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a968835-50ab-33df-bf5e-42de32d01c15"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-02e70892-6694-4917-abc4-04073abdfae8.json b/src/enm/study-NWKI-02e70892-6694-4917-abc4-04073abdfae8.json
new file mode 100644
index 0000000..e80fe03
--- /dev/null
+++ b/src/enm/study-NWKI-02e70892-6694-4917-abc4-04073abdfae8.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-02e70892-6694-4917-abc4-04073abdfae8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a855e2c5-73f1-32c0-8a87-aa521fd69928"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1063/1.2061873",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0352bf48-fe8a-4121-a3c8-c996b2c7416b.json b/src/enm/study-NWKI-0352bf48-fe8a-4121-a3c8-c996b2c7416b.json
new file mode 100644
index 0000000..4f72fb2
--- /dev/null
+++ b/src/enm/study-NWKI-0352bf48-fe8a-4121-a3c8-c996b2c7416b.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-0352bf48-fe8a-4121-a3c8-c996b2c7416b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-1b7ce9a9-7e13-30d8-a5c2-f8008ba3c38f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -72.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-037a45cf-b93d-4621-a584-a77e5b4ed359.json b/src/enm/study-NWKI-037a45cf-b93d-4621-a584-a77e5b4ed359.json
new file mode 100644
index 0000000..a81ee66
--- /dev/null
+++ b/src/enm/study-NWKI-037a45cf-b93d-4621-a584-a77e5b4ed359.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-037a45cf-b93d-4621-a584-a77e5b4ed359",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-674cfd7c-bc77-36c7-bbe0-d52dd0233d64"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loQualifier": ">=",
+ "loValue": 50,
+ "upQualifier": "<=",
+ "upValue": 245
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-03c2146b-f531-4e6e-9092-c1faf2894574.json b/src/enm/study-NWKI-03c2146b-f531-4e6e-9092-c1faf2894574.json
new file mode 100644
index 0000000..bc3a9d2
--- /dev/null
+++ b/src/enm/study-NWKI-03c2146b-f531-4e6e-9092-c1faf2894574.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-03c2146b-f531-4e6e-9092-c1faf2894574",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6cab56b4-69d9-36e0-8c17-f467d08b2555"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH-2DPVA"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-040aa132-1030-4a06-80a9-e70d75d68429.json b/src/enm/study-NWKI-040aa132-1030-4a06-80a9-e70d75d68429.json
new file mode 100644
index 0000000..5dc4e35
--- /dev/null
+++ b/src/enm/study-NWKI-040aa132-1030-4a06-80a9-e70d75d68429.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-040aa132-1030-4a06-80a9-e70d75d68429",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9f37da26-8619-3eb1-9c29-e5f9ea09de54"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 500,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
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+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-040afb18-8fc4-4be2-8d1a-35f506470c0a.json b/src/enm/study-NWKI-040afb18-8fc4-4be2-8d1a-35f506470c0a.json
new file mode 100644
index 0000000..7b5a061
--- /dev/null
+++ b/src/enm/study-NWKI-040afb18-8fc4-4be2-8d1a-35f506470c0a.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-040afb18-8fc4-4be2-8d1a-35f506470c0a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-19b5dfef-0d95-3878-9075-2897e8631277"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3390/ijerph110908867",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20,
+ "errorValue": 4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-04792111-4a88-4b55-8c06-630900a232b4.json b/src/enm/study-NWKI-04792111-4a88-4b55-8c06-630900a232b4.json
new file mode 100644
index 0000000..15de0b5
--- /dev/null
+++ b/src/enm/study-NWKI-04792111-4a88-4b55-8c06-630900a232b4.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-04792111-4a88-4b55-8c06-630900a232b4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bb2f1a47-0260-3271-b9c3-edb850d15be9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1039/C4FD00117F",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "Å",
+ "loQualifier": ">=",
+ "loValue": 25,
+ "upQualifier": "<=",
+ "upValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-04ce206c-a682-4005-8758-4afdb04152c1.json b/src/enm/study-NWKI-04ce206c-a682-4005-8758-4afdb04152c1.json
new file mode 100644
index 0000000..d71a52a
--- /dev/null
+++ b/src/enm/study-NWKI-04ce206c-a682-4005-8758-4afdb04152c1.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-04ce206c-a682-4005-8758-4afdb04152c1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 80
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-04db465c-6485-4cf7-ba99-79ebf0b8ed0b.json b/src/enm/study-NWKI-04db465c-6485-4cf7-ba99-79ebf0b8ed0b.json
new file mode 100644
index 0000000..d9575ce
--- /dev/null
+++ b/src/enm/study-NWKI-04db465c-6485-4cf7-ba99-79ebf0b8ed0b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-04db465c-6485-4cf7-ba99-79ebf0b8ed0b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-823e6217-d5b0-3c61-b886-768cfe726d38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 65,
+ "errorValue": 18
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-05229c6c-cb12-4dec-b919-4322f75c61a7.json b/src/enm/study-NWKI-05229c6c-cb12-4dec-b919-4322f75c61a7.json
new file mode 100644
index 0000000..a9f0835
--- /dev/null
+++ b/src/enm/study-NWKI-05229c6c-cb12-4dec-b919-4322f75c61a7.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-05229c6c-cb12-4dec-b919-4322f75c61a7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 0
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0534ae85-3e71-44df-bb0f-3250d66e566a.json b/src/enm/study-NWKI-0534ae85-3e71-44df-bb0f-3250d66e566a.json
new file mode 100644
index 0000000..7033f66
--- /dev/null
+++ b/src/enm/study-NWKI-0534ae85-3e71-44df-bb0f-3250d66e566a.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-0534ae85-3e71-44df-bb0f-3250d66e566a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b19125a9-4499-3e0e-aa0c-7792401f4900"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DProtamine-2DRhodamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Protamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Protamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-05fe5e71-840f-4547-b1e5-0da0b4a50043.json b/src/enm/study-NWKI-05fe5e71-840f-4547-b1e5-0da0b4a50043.json
new file mode 100644
index 0000000..c542e8f
--- /dev/null
+++ b/src/enm/study-NWKI-05fe5e71-840f-4547-b1e5-0da0b4a50043.json
@@ -0,0 +1,54 @@
+{
+ "uuid": "NWKI-05fe5e71-840f-4547-b1e5-0da0b4a50043",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c93a144a-cd6d-3fe0-ab86-13adb168ccb1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_BOILING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000257",
+ "title": "4.3 Boiling point"
+ },
+ "endpoint": "Boiling Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Boiling point",
+ "conditions": {
+ "Atm. Pressure": null,
+ "Decomposition": null
+ },
+ "result": {
+ "unit": "Celsius",
+ "loValue": 2230
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0603f68c-d040-45ee-a86f-e286e0b42fba.json b/src/enm/study-NWKI-0603f68c-d040-45ee-a86f-e286e0b42fba.json
new file mode 100644
index 0000000..522cdbf
--- /dev/null
+++ b/src/enm/study-NWKI-0603f68c-d040-45ee-a86f-e286e0b42fba.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-0603f68c-d040-45ee-a86f-e286e0b42fba",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-144a9226-4b93-36a9-ba2d-6b6c4903357b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "cMEM"
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 206
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0721f8d0-f670-4579-90c7-6ceea91fa757.json b/src/enm/study-NWKI-0721f8d0-f670-4579-90c7-6ceea91fa757.json
new file mode 100644
index 0000000..8a1672a
--- /dev/null
+++ b/src/enm/study-NWKI-0721f8d0-f670-4579-90c7-6ceea91fa757.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-0721f8d0-f670-4579-90c7-6ceea91fa757",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-07bdb9ac-d6b8-49ed-9e70-c0a4e689b500.json b/src/enm/study-NWKI-07bdb9ac-d6b8-49ed-9e70-c0a4e689b500.json
new file mode 100644
index 0000000..c6ecf72
--- /dev/null
+++ b/src/enm/study-NWKI-07bdb9ac-d6b8-49ed-9e70-c0a4e689b500.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-07bdb9ac-d6b8-49ed-9e70-c0a4e689b500",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5eff14ab-be8b-3f57-96fc-7ed09e7546b5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-07be4b7f-0887-463d-b691-f394d8ea38e9.json b/src/enm/study-NWKI-07be4b7f-0887-463d-b691-f394d8ea38e9.json
new file mode 100644
index 0000000..b6b0411
--- /dev/null
+++ b/src/enm/study-NWKI-07be4b7f-0887-463d-b691-f394d8ea38e9.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-07be4b7f-0887-463d-b691-f394d8ea38e9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d42892b8-9b57-30a2-aa89-af61880c337a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "SucroseCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Sucrose"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Sucrose"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-08af89f3-bfa5-4d48-b6f4-223f642ad984.json b/src/enm/study-NWKI-08af89f3-bfa5-4d48-b6f4-223f642ad984.json
new file mode 100644
index 0000000..ec5fe8c
--- /dev/null
+++ b/src/enm/study-NWKI-08af89f3-bfa5-4d48-b6f4-223f642ad984.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-08af89f3-bfa5-4d48-b6f4-223f642ad984",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ee237892-6184-3016-92af-b41dc14e9f9b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DNH2"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "NH2"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "[H]N[H]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "NH2"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-08d213c8-9de2-402c-ac0a-91c76b9a1541.json b/src/enm/study-NWKI-08d213c8-9de2-402c-ac0a-91c76b9a1541.json
new file mode 100644
index 0000000..d3b6a63
--- /dev/null
+++ b/src/enm/study-NWKI-08d213c8-9de2-402c-ac0a-91c76b9a1541.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-08d213c8-9de2-402c-ac0a-91c76b9a1541",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-227a54df-573f-3515-8366-6bf1f17dd715"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 40.1,
+ "errorValue": 12.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-08e4b07b-144b-4d9c-9bf6-9d8228dd1846.json b/src/enm/study-NWKI-08e4b07b-144b-4d9c-9bf6-9d8228dd1846.json
new file mode 100644
index 0000000..eacd969
--- /dev/null
+++ b/src/enm/study-NWKI-08e4b07b-144b-4d9c-9bf6-9d8228dd1846.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-08e4b07b-144b-4d9c-9bf6-9d8228dd1846",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4beee533-65e4-364a-adb7-7a520180de61"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_value": null
+ },
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+ "effects": [
+ {
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+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 34
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0b166019-f410-4706-9eea-e821785aede7.json b/src/enm/study-NWKI-0b166019-f410-4706-9eea-e821785aede7.json
new file mode 100644
index 0000000..455e9a4
--- /dev/null
+++ b/src/enm/study-NWKI-0b166019-f410-4706-9eea-e821785aede7.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-0b166019-f410-4706-9eea-e821785aede7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0fef8d9c-b0c4-3e41-88d0-b85cd538a796"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0b35977c-affa-4eb8-9861-35beca1a42ad.json b/src/enm/study-NWKI-0b35977c-affa-4eb8-9861-35beca1a42ad.json
new file mode 100644
index 0000000..ef11bd4
--- /dev/null
+++ b/src/enm/study-NWKI-0b35977c-affa-4eb8-9861-35beca1a42ad.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-0b35977c-affa-4eb8-9861-35beca1a42ad",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f90f7f33-091c-3d54-b313-213083c0e052"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1039/C4FD00117F",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "Å",
+ "loQualifier": ">=",
+ "loValue": 25,
+ "upQualifier": "<=",
+ "upValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0b384935-1f9a-4fa2-8927-b1cdce466220.json b/src/enm/study-NWKI-0b384935-1f9a-4fa2-8927-b1cdce466220.json
new file mode 100644
index 0000000..83fec18
--- /dev/null
+++ b/src/enm/study-NWKI-0b384935-1f9a-4fa2-8927-b1cdce466220.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-0b384935-1f9a-4fa2-8927-b1cdce466220",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a33b26f0-2fc7-3aa1-9dd6-27380f725bfe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.49
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0b3cce4b-154f-44ce-ae76-d549863886c4.json b/src/enm/study-NWKI-0b3cce4b-154f-44ce-ae76-d549863886c4.json
new file mode 100644
index 0000000..6fb5bcf
--- /dev/null
+++ b/src/enm/study-NWKI-0b3cce4b-154f-44ce-ae76-d549863886c4.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-0b3cce4b-154f-44ce-ae76-d549863886c4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3db8eb74-b206-31ad-8c1b-3569703c47cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 96
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0b7e9c74-ed51-4702-9ba9-8c6c800fa192.json b/src/enm/study-NWKI-0b7e9c74-ed51-4702-9ba9-8c6c800fa192.json
new file mode 100644
index 0000000..a5ce315
--- /dev/null
+++ b/src/enm/study-NWKI-0b7e9c74-ed51-4702-9ba9-8c6c800fa192.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-0b7e9c74-ed51-4702-9ba9-8c6c800fa192",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0c083777-ee10-428d-b73a-d284574e691f.json b/src/enm/study-NWKI-0c083777-ee10-428d-b73a-d284574e691f.json
new file mode 100644
index 0000000..796f3b5
--- /dev/null
+++ b/src/enm/study-NWKI-0c083777-ee10-428d-b73a-d284574e691f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-0c083777-ee10-428d-b73a-d284574e691f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 286,
+ "errorValue": 2.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0c606592-8bc3-4922-b065-2df3dbfe66d7.json b/src/enm/study-NWKI-0c606592-8bc3-4922-b065-2df3dbfe66d7.json
new file mode 100644
index 0000000..9ac4be5
--- /dev/null
+++ b/src/enm/study-NWKI-0c606592-8bc3-4922-b065-2df3dbfe66d7.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-0c606592-8bc3-4922-b065-2df3dbfe66d7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0cb40fcb-8551-4cd3-953b-ac7e29928e05.json b/src/enm/study-NWKI-0cb40fcb-8551-4cd3-953b-ac7e29928e05.json
new file mode 100644
index 0000000..1bf5330
--- /dev/null
+++ b/src/enm/study-NWKI-0cb40fcb-8551-4cd3-953b-ac7e29928e05.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-0cb40fcb-8551-4cd3-953b-ac7e29928e05",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2944da02-ade8-38cc-b547-504f6afcf25a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2011.587903",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 21
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0d65feb5-c903-4fdd-8c52-033527bcace7.json b/src/enm/study-NWKI-0d65feb5-c903-4fdd-8c52-033527bcace7.json
new file mode 100644
index 0000000..a27240f
--- /dev/null
+++ b/src/enm/study-NWKI-0d65feb5-c903-4fdd-8c52-033527bcace7.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-0d65feb5-c903-4fdd-8c52-033527bcace7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2bd4c991-b6fb-3eb3-8a0c-794607388b79"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 200
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0e21641a-22b9-4bc8-97f5-54d6ca3ee00a.json b/src/enm/study-NWKI-0e21641a-22b9-4bc8-97f5-54d6ca3ee00a.json
new file mode 100644
index 0000000..5a44046
--- /dev/null
+++ b/src/enm/study-NWKI-0e21641a-22b9-4bc8-97f5-54d6ca3ee00a.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-0e21641a-22b9-4bc8-97f5-54d6ca3ee00a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 52,
+ "errorValue": 0.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0e6ea55b-a5f0-4e1b-a6ac-be5048dd4299.json b/src/enm/study-NWKI-0e6ea55b-a5f0-4e1b-a6ac-be5048dd4299.json
new file mode 100644
index 0000000..15fc8b8
--- /dev/null
+++ b/src/enm/study-NWKI-0e6ea55b-a5f0-4e1b-a6ac-be5048dd4299.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-0e6ea55b-a5f0-4e1b-a6ac-be5048dd4299",
+ "owner": {
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+ "title": "4.5 Particle size distribution (Granulometry)"
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diff --git a/src/enm/study-NWKI-0e875328-7a36-4c40-b123-ceba2d7322b1.json b/src/enm/study-NWKI-0e875328-7a36-4c40-b123-ceba2d7322b1.json
new file mode 100644
index 0000000..fe8ebe4
--- /dev/null
+++ b/src/enm/study-NWKI-0e875328-7a36-4c40-b123-ceba2d7322b1.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-0e875328-7a36-4c40-b123-ceba2d7322b1",
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+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
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+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
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diff --git a/src/enm/study-NWKI-0f073653-0c7b-422f-bb30-207c0d74f834.json b/src/enm/study-NWKI-0f073653-0c7b-422f-bb30-207c0d74f834.json
new file mode 100644
index 0000000..92c84e2
--- /dev/null
+++ b/src/enm/study-NWKI-0f073653-0c7b-422f-bb30-207c0d74f834.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-0f073653-0c7b-422f-bb30-207c0d74f834",
+ "owner": {
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
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diff --git a/src/enm/study-NWKI-0f441ae1-e2e7-47e6-9199-bcb0333142fb.json b/src/enm/study-NWKI-0f441ae1-e2e7-47e6-9199-bcb0333142fb.json
new file mode 100644
index 0000000..bae656d
--- /dev/null
+++ b/src/enm/study-NWKI-0f441ae1-e2e7-47e6-9199-bcb0333142fb.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-0f441ae1-e2e7-47e6-9199-bcb0333142fb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5136670d-2925-31d0-8e12-811f8d67677f"
+ },
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "category": {
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
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diff --git a/src/enm/study-NWKI-0f714533-2dbe-4d3f-964b-6439e106f9a0.json b/src/enm/study-NWKI-0f714533-2dbe-4d3f-964b-6439e106f9a0.json
new file mode 100644
index 0000000..f974356
--- /dev/null
+++ b/src/enm/study-NWKI-0f714533-2dbe-4d3f-964b-6439e106f9a0.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-0f714533-2dbe-4d3f-964b-6439e106f9a0",
+ "owner": {
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+ "name": "NanoWiki"
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+ "owner": "NanoWiki"
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+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
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+ "endpoint": "Unknown",
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+ "textValue": "Ag"
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+ "endpoint": "ATOMIC COMPOSITION",
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+ "loValue": "MEEECoating"
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diff --git a/src/enm/study-NWKI-0fd9f570-8e2b-4ea0-b8d3-e710aa4a6dc6.json b/src/enm/study-NWKI-0fd9f570-8e2b-4ea0-b8d3-e710aa4a6dc6.json
new file mode 100644
index 0000000..840cb24
--- /dev/null
+++ b/src/enm/study-NWKI-0fd9f570-8e2b-4ea0-b8d3-e710aa4a6dc6.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-0fd9f570-8e2b-4ea0-b8d3-e710aa4a6dc6",
+ "owner": {
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+ "uuid": "NWKI-ff85c0ea-c908-35c8-9f1c-bfd037800a31"
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+ "name": "NanoWiki"
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+ "year": "0",
+ "owner": "NanoWiki"
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+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
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+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-0fea1498-1740-4855-a77d-55ade5307ea5.json b/src/enm/study-NWKI-0fea1498-1740-4855-a77d-55ade5307ea5.json
new file mode 100644
index 0000000..eac0181
--- /dev/null
+++ b/src/enm/study-NWKI-0fea1498-1740-4855-a77d-55ade5307ea5.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-0fea1498-1740-4855-a77d-55ade5307ea5",
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
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+ ]
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+ ]
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diff --git a/src/enm/study-NWKI-103813a2-d0f6-404e-a8e3-19328f87646c.json b/src/enm/study-NWKI-103813a2-d0f6-404e-a8e3-19328f87646c.json
new file mode 100644
index 0000000..e30d031
--- /dev/null
+++ b/src/enm/study-NWKI-103813a2-d0f6-404e-a8e3-19328f87646c.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-103813a2-d0f6-404e-a8e3-19328f87646c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-072b1631-f6f1-3f47-a4dc-723aa4eb0700"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn200546k",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+ }
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+}
diff --git a/src/enm/study-NWKI-10979332-7b4a-427c-8f60-ddd044c02a91.json b/src/enm/study-NWKI-10979332-7b4a-427c-8f60-ddd044c02a91.json
new file mode 100644
index 0000000..accdd96
--- /dev/null
+++ b/src/enm/study-NWKI-10979332-7b4a-427c-8f60-ddd044c02a91.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-10979332-7b4a-427c-8f60-ddd044c02a91",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+}
diff --git a/src/enm/study-NWKI-10fafc91-a412-4a1e-8434-40f70326e50e.json b/src/enm/study-NWKI-10fafc91-a412-4a1e-8434-40f70326e50e.json
new file mode 100644
index 0000000..c7df5cb
--- /dev/null
+++ b/src/enm/study-NWKI-10fafc91-a412-4a1e-8434-40f70326e50e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-10fafc91-a412-4a1e-8434-40f70326e50e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4358aa69-dec1-387a-b7ea-2238198ccdff"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "reliability": {
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+ "Serum": {
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+}
diff --git a/src/enm/study-NWKI-11640aa5-704e-4c6e-b85d-2006d4cfe282.json b/src/enm/study-NWKI-11640aa5-704e-4c6e-b85d-2006d4cfe282.json
new file mode 100644
index 0000000..cf97154
--- /dev/null
+++ b/src/enm/study-NWKI-11640aa5-704e-4c6e-b85d-2006d4cfe282.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-11640aa5-704e-4c6e-b85d-2006d4cfe282",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-11826ae4-fd66-4f96-b3ee-05b4d9a35b2b.json b/src/enm/study-NWKI-11826ae4-fd66-4f96-b3ee-05b4d9a35b2b.json
new file mode 100644
index 0000000..83e0252
--- /dev/null
+++ b/src/enm/study-NWKI-11826ae4-fd66-4f96-b3ee-05b4d9a35b2b.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-11826ae4-fd66-4f96-b3ee-05b4d9a35b2b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a968835-50ab-33df-bf5e-42de32d01c15"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-11c639bc-a4f6-48dd-b84f-c115cd68383f.json b/src/enm/study-NWKI-11c639bc-a4f6-48dd-b84f-c115cd68383f.json
new file mode 100644
index 0000000..4bf1642
--- /dev/null
+++ b/src/enm/study-NWKI-11c639bc-a4f6-48dd-b84f-c115cd68383f.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-11c639bc-a4f6-48dd-b84f-c115cd68383f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ae0be5b8-266b-3b6a-825d-55f14b51cc99"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DArg7COOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "L-2DArginine-2D7-2DCOOH"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "L-2DArginine-2D7-2DCOOH"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-11ce2c1b-a219-4fc7-841d-add4602b708b.json b/src/enm/study-NWKI-11ce2c1b-a219-4fc7-841d-add4602b708b.json
new file mode 100644
index 0000000..5eec69b
--- /dev/null
+++ b/src/enm/study-NWKI-11ce2c1b-a219-4fc7-841d-add4602b708b.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-11ce2c1b-a219-4fc7-841d-add4602b708b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3c8c8bb2-416f-3bff-862a-8433538cd4c5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": -20,
+ "upQualifier": "<=",
+ "upValue": 35
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1256873c-3d55-42c7-a833-912946549b1b.json b/src/enm/study-NWKI-1256873c-3d55-42c7-a833-912946549b1b.json
new file mode 100644
index 0000000..d2e5783
--- /dev/null
+++ b/src/enm/study-NWKI-1256873c-3d55-42c7-a833-912946549b1b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-1256873c-3d55-42c7-a833-912946549b1b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1.6,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-12ba0164-b75b-4dfc-9571-cade11e8b178.json b/src/enm/study-NWKI-12ba0164-b75b-4dfc-9571-cade11e8b178.json
new file mode 100644
index 0000000..eea84a5
--- /dev/null
+++ b/src/enm/study-NWKI-12ba0164-b75b-4dfc-9571-cade11e8b178.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-12ba0164-b75b-4dfc-9571-cade11e8b178",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "BET",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 50
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-12dd4a77-2368-4a9c-b7a3-2f786aaf3bab.json b/src/enm/study-NWKI-12dd4a77-2368-4a9c-b7a3-2f786aaf3bab.json
new file mode 100644
index 0000000..5407faf
--- /dev/null
+++ b/src/enm/study-NWKI-12dd4a77-2368-4a9c-b7a3-2f786aaf3bab.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-12dd4a77-2368-4a9c-b7a3-2f786aaf3bab",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-69b604fb-e892-31ba-a6f5-feb6cb04effb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DAF750"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-12f2840e-a312-4d32-8e61-e204b0c782fc.json b/src/enm/study-NWKI-12f2840e-a312-4d32-8e61-e204b0c782fc.json
new file mode 100644
index 0000000..2194c45
--- /dev/null
+++ b/src/enm/study-NWKI-12f2840e-a312-4d32-8e61-e204b0c782fc.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-12f2840e-a312-4d32-8e61-e204b0c782fc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e6ef5597-a3f9-3f21-afff-db5f654ef534"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.29
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-133b31f5-75fb-4baa-9d21-20bbe6524d9d.json b/src/enm/study-NWKI-133b31f5-75fb-4baa-9d21-20bbe6524d9d.json
new file mode 100644
index 0000000..0e5166e
--- /dev/null
+++ b/src/enm/study-NWKI-133b31f5-75fb-4baa-9d21-20bbe6524d9d.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-133b31f5-75fb-4baa-9d21-20bbe6524d9d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9f37da26-8619-3eb1-9c29-e5f9ea09de54"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1000,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 92
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1349c808-40d3-4a58-aeed-e86dd738690e.json b/src/enm/study-NWKI-1349c808-40d3-4a58-aeed-e86dd738690e.json
new file mode 100644
index 0000000..0e9e013
--- /dev/null
+++ b/src/enm/study-NWKI-1349c808-40d3-4a58-aeed-e86dd738690e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-1349c808-40d3-4a58-aeed-e86dd738690e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3ccb7313-0905-322a-ac62-09adb667bc0f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Average Length",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Average Length",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "μm",
+ "loQualifier": ">=",
+ "loValue": 5,
+ "upQualifier": "<=",
+ "upValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1384c6b9-9050-4f24-8a83-94f1ce913a4e.json b/src/enm/study-NWKI-1384c6b9-9050-4f24-8a83-94f1ce913a4e.json
new file mode 100644
index 0000000..3e95888
--- /dev/null
+++ b/src/enm/study-NWKI-1384c6b9-9050-4f24-8a83-94f1ce913a4e.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-1384c6b9-9050-4f24-8a83-94f1ce913a4e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ff480524-2eb0-39e2-a449-47c026f09eb9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 18.4,
+ "errorValue": 0.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-13e65857-d4ca-4c7a-803a-342b8fa4183b.json b/src/enm/study-NWKI-13e65857-d4ca-4c7a-803a-342b8fa4183b.json
new file mode 100644
index 0000000..ff62e37
--- /dev/null
+++ b/src/enm/study-NWKI-13e65857-d4ca-4c7a-803a-342b8fa4183b.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-13e65857-d4ca-4c7a-803a-342b8fa4183b",
+ "owner": {
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+ "title": "4.29 Nanomaterial zeta potential"
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+ "endpoint": "Zeta Potential",
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diff --git a/src/enm/study-NWKI-13fbf7ad-6fc4-4b94-9a9d-3e66c612fa4c.json b/src/enm/study-NWKI-13fbf7ad-6fc4-4b94-9a9d-3e66c612fa4c.json
new file mode 100644
index 0000000..c35e987
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+++ b/src/enm/study-NWKI-13fbf7ad-6fc4-4b94-9a9d-3e66c612fa4c.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-13fbf7ad-6fc4-4b94-9a9d-3e66c612fa4c",
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
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+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
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+ }
+ ]
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diff --git a/src/enm/study-NWKI-14265abe-890f-4648-83e6-9f148a05107f.json b/src/enm/study-NWKI-14265abe-890f-4648-83e6-9f148a05107f.json
new file mode 100644
index 0000000..2963c9b
--- /dev/null
+++ b/src/enm/study-NWKI-14265abe-890f-4648-83e6-9f148a05107f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-14265abe-890f-4648-83e6-9f148a05107f",
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+ "uuid": "NWKI-2af8ed34-029d-3644-8327-23a596cfae0d"
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
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+ },
+ "endpoint": "Particle Size",
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+ ""
+ ]
+ },
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+ "SEQ_NUM": null
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+}
diff --git a/src/enm/study-NWKI-1540f00c-e7aa-4d25-ab3b-a6a05a7060cf.json b/src/enm/study-NWKI-1540f00c-e7aa-4d25-ab3b-a6a05a7060cf.json
new file mode 100644
index 0000000..dc930d8
--- /dev/null
+++ b/src/enm/study-NWKI-1540f00c-e7aa-4d25-ab3b-a6a05a7060cf.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-1540f00c-e7aa-4d25-ab3b-a6a05a7060cf",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e518c122-5f4f-3611-8b30-56b671883e5c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ },
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+ "endpoint": "ATOMIC COMPOSITION",
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+ "ELEMENT_OR_GROUP": {
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+ "loValue": "Fe2O3"
+ },
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+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
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+ "loValue": "PVA-2DED-2DAminoSPARK680"
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+ "TYPE": {
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+ }
+ },
+ "result": {
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+ "textValue": "Amino_SPARK680"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-157c1f0e-0344-4310-9fca-ac778f7c3501.json b/src/enm/study-NWKI-157c1f0e-0344-4310-9fca-ac778f7c3501.json
new file mode 100644
index 0000000..f875a77
--- /dev/null
+++ b/src/enm/study-NWKI-157c1f0e-0344-4310-9fca-ac778f7c3501.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-157c1f0e-0344-4310-9fca-ac778f7c3501",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2390517f-b763-3850-b1b4-6e50fee63829"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
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+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
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+ "loValue": 2.81
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1599e8df-9aca-495a-b200-3a79e17f4725.json b/src/enm/study-NWKI-1599e8df-9aca-495a-b200-3a79e17f4725.json
new file mode 100644
index 0000000..16e16e2
--- /dev/null
+++ b/src/enm/study-NWKI-1599e8df-9aca-495a-b200-3a79e17f4725.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-1599e8df-9aca-495a-b200-3a79e17f4725",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b8a44a2-b835-3f75-903c-cf0a71a247c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
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+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
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+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 3,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 18
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1616676d-cef0-48d9-84b5-0a5fe92b2705.json b/src/enm/study-NWKI-1616676d-cef0-48d9-84b5-0a5fe92b2705.json
new file mode 100644
index 0000000..df34a81
--- /dev/null
+++ b/src/enm/study-NWKI-1616676d-cef0-48d9-84b5-0a5fe92b2705.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-1616676d-cef0-48d9-84b5-0a5fe92b2705",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-77fb742b-c676-3ad7-bd19-6d5ec1df62ad"
+ },
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
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+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ },
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+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "DESCRIPTION": {
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+ }
+ },
+ "result": {
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+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1663bbb9-45a2-4a1f-b694-e960165592ff.json b/src/enm/study-NWKI-1663bbb9-45a2-4a1f-b694-e960165592ff.json
new file mode 100644
index 0000000..8d1337a
--- /dev/null
+++ b/src/enm/study-NWKI-1663bbb9-45a2-4a1f-b694-e960165592ff.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-1663bbb9-45a2-4a1f-b694-e960165592ff",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7d4e9d59-fb38-37b9-99ec-b150ed7ce133"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ "Type of method": null
+ },
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+ "effects": [
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+ "Remark": null,
+ "pH": {
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+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 10,
+ "errorValue": 2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1680e54d-dc50-46e5-beb2-725261d70e42.json b/src/enm/study-NWKI-1680e54d-dc50-46e5-beb2-725261d70e42.json
new file mode 100644
index 0000000..4688f9e
--- /dev/null
+++ b/src/enm/study-NWKI-1680e54d-dc50-46e5-beb2-725261d70e42.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-1680e54d-dc50-46e5-beb2-725261d70e42",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-92e20781-9c38-3c12-a311-14eab1e776fa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
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+ "interpretation": {
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+ "effects": [
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+ "Remark": null,
+ "pH": {
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+ }
+ },
+ "result": {
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+ "loValue": -61.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-16943eea-e6e8-4f59-b660-6bf1f4876dbf.json b/src/enm/study-NWKI-16943eea-e6e8-4f59-b660-6bf1f4876dbf.json
new file mode 100644
index 0000000..636d0a7
--- /dev/null
+++ b/src/enm/study-NWKI-16943eea-e6e8-4f59-b660-6bf1f4876dbf.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-16943eea-e6e8-4f59-b660-6bf1f4876dbf",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cad5bf58-cc90-33e5-88bb-bad4c9f9fe9e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 28
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-16a4b79d-ba53-4885-a2b8-f4204bf105d5.json b/src/enm/study-NWKI-16a4b79d-ba53-4885-a2b8-f4204bf105d5.json
new file mode 100644
index 0000000..3b89e72
--- /dev/null
+++ b/src/enm/study-NWKI-16a4b79d-ba53-4885-a2b8-f4204bf105d5.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-16a4b79d-ba53-4885-a2b8-f4204bf105d5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3ccb7313-0905-322a-ac62-09adb667bc0f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Diameter",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Diameter",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 10,
+ "upQualifier": "<=",
+ "upValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-16d02082-1ba3-4510-b59e-403abf8f1d23.json b/src/enm/study-NWKI-16d02082-1ba3-4510-b59e-403abf8f1d23.json
new file mode 100644
index 0000000..69ccfdc
--- /dev/null
+++ b/src/enm/study-NWKI-16d02082-1ba3-4510-b59e-403abf8f1d23.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-16d02082-1ba3-4510-b59e-403abf8f1d23",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-95bb8173-3aad-3441-a50e-97e62401eadb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1039/C4FD00117F",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "Å",
+ "loQualifier": ">=",
+ "loValue": 25,
+ "upQualifier": "<=",
+ "upValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-17092417-17a0-4373-84f2-da1d50f4d32c.json b/src/enm/study-NWKI-17092417-17a0-4373-84f2-da1d50f4d32c.json
new file mode 100644
index 0000000..8241ef5
--- /dev/null
+++ b/src/enm/study-NWKI-17092417-17a0-4373-84f2-da1d50f4d32c.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-17092417-17a0-4373-84f2-da1d50f4d32c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-11ae9232-1521-31d6-9466-c902c43d94fe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DTatPeptide"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-173dce50-8e10-4eb6-8606-86a64f77aa63.json b/src/enm/study-NWKI-173dce50-8e10-4eb6-8606-86a64f77aa63.json
new file mode 100644
index 0000000..3a49580
--- /dev/null
+++ b/src/enm/study-NWKI-173dce50-8e10-4eb6-8606-86a64f77aa63.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-173dce50-8e10-4eb6-8606-86a64f77aa63",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-86b21444-5403-3e29-b117-e09ef92cca2a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Isoelectric Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ISOELECTRIC POINT",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 5.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-17738fdb-85b1-4bee-91c6-ce6784ade433.json b/src/enm/study-NWKI-17738fdb-85b1-4bee-91c6-ce6784ade433.json
new file mode 100644
index 0000000..01652bb
--- /dev/null
+++ b/src/enm/study-NWKI-17738fdb-85b1-4bee-91c6-ce6784ade433.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-17738fdb-85b1-4bee-91c6-ce6784ade433",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9f37da26-8619-3eb1-9c29-e5f9ea09de54"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 101
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-17b02ae9-1dd2-4a6a-8162-4ed9e0e25770.json b/src/enm/study-NWKI-17b02ae9-1dd2-4a6a-8162-4ed9e0e25770.json
new file mode 100644
index 0000000..be5ca0c
--- /dev/null
+++ b/src/enm/study-NWKI-17b02ae9-1dd2-4a6a-8162-4ed9e0e25770.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-17b02ae9-1dd2-4a6a-8162-4ed9e0e25770",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0a6e319e-71fc-37f7-b88d-fbda2e07ccc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 283,
+ "errorValue": 7.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-180c42f0-dd92-422b-a704-2cede4ecd197.json b/src/enm/study-NWKI-180c42f0-dd92-422b-a704-2cede4ecd197.json
new file mode 100644
index 0000000..daa50b2
--- /dev/null
+++ b/src/enm/study-NWKI-180c42f0-dd92-422b-a704-2cede4ecd197.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-180c42f0-dd92-422b-a704-2cede4ecd197",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3424add5-867e-3dc5-864d-36c47589024b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 7
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 10,
+ "errorValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-18542d3a-af3b-409e-867a-37ce489931fe.json b/src/enm/study-NWKI-18542d3a-af3b-409e-867a-37ce489931fe.json
new file mode 100644
index 0000000..1d6e7d3
--- /dev/null
+++ b/src/enm/study-NWKI-18542d3a-af3b-409e-867a-37ce489931fe.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-18542d3a-af3b-409e-867a-37ce489931fe",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-18971884-ccca-4501-afc3-483cbc30d80e.json b/src/enm/study-NWKI-18971884-ccca-4501-afc3-483cbc30d80e.json
new file mode 100644
index 0000000..f3b8575
--- /dev/null
+++ b/src/enm/study-NWKI-18971884-ccca-4501-afc3-483cbc30d80e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-18971884-ccca-4501-afc3-483cbc30d80e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6d5462cc-7e11-3919-b769-135f56fd2536"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.soilbio.2013.01.016",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 50,
+ "upQualifier": "<=",
+ "upValue": 105
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-18eacf9a-c155-4ed7-8c75-10cac75f1858.json b/src/enm/study-NWKI-18eacf9a-c155-4ed7-8c75-10cac75f1858.json
new file mode 100644
index 0000000..67794c8
--- /dev/null
+++ b/src/enm/study-NWKI-18eacf9a-c155-4ed7-8c75-10cac75f1858.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-18eacf9a-c155-4ed7-8c75-10cac75f1858",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ad1d5068-29cd-3d8c-9ed0-44ed4ce06ddd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
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+ "loValue": -21.9
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-18ecc7e2-69c6-456f-a6f9-35acc32c95d4.json b/src/enm/study-NWKI-18ecc7e2-69c6-456f-a6f9-35acc32c95d4.json
new file mode 100644
index 0000000..49ca642
--- /dev/null
+++ b/src/enm/study-NWKI-18ecc7e2-69c6-456f-a6f9-35acc32c95d4.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-18ecc7e2-69c6-456f-a6f9-35acc32c95d4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ef8660fd-e624-3a94-91bc-ad5a6e47bcf3"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -14.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-18f29d40-3b2e-4bd9-8fe1-049810cbbbb4.json b/src/enm/study-NWKI-18f29d40-3b2e-4bd9-8fe1-049810cbbbb4.json
new file mode 100644
index 0000000..94374f0
--- /dev/null
+++ b/src/enm/study-NWKI-18f29d40-3b2e-4bd9-8fe1-049810cbbbb4.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-18f29d40-3b2e-4bd9-8fe1-049810cbbbb4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3bbccc84-019f-369f-ba70-490fcfde4423"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.01
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1a0ef2d1-139d-4c40-8b48-602061cc52b5.json b/src/enm/study-NWKI-1a0ef2d1-139d-4c40-8b48-602061cc52b5.json
new file mode 100644
index 0000000..f4e4477
--- /dev/null
+++ b/src/enm/study-NWKI-1a0ef2d1-139d-4c40-8b48-602061cc52b5.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-1a0ef2d1-139d-4c40-8b48-602061cc52b5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-80f9ab46-f8fe-36de-9335-17c9d1dbdba5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2015.1017022",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Average Length",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Average Length",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "μm",
+ "loValue": 21,
+ "errorValue": 18
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1aa514a8-41a9-4f83-b809-b27d84e9533f.json b/src/enm/study-NWKI-1aa514a8-41a9-4f83-b809-b27d84e9533f.json
new file mode 100644
index 0000000..c3680d9
--- /dev/null
+++ b/src/enm/study-NWKI-1aa514a8-41a9-4f83-b809-b27d84e9533f.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-1aa514a8-41a9-4f83-b809-b27d84e9533f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ab2d4bdd-7a72-3e26-8552-5bb6027896bb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12,
+ "errorValue": 7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1b01ed49-5212-4774-b777-9ff22f324e2f.json b/src/enm/study-NWKI-1b01ed49-5212-4774-b777-9ff22f324e2f.json
new file mode 100644
index 0000000..35501c2
--- /dev/null
+++ b/src/enm/study-NWKI-1b01ed49-5212-4774-b777-9ff22f324e2f.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-1b01ed49-5212-4774-b777-9ff22f324e2f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c075299c-c306-341a-8ccb-62c5bd123ab3"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 140.6,
+ "errorValue": 52.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1b674a0a-fa78-48e5-b76c-147e56f8d237.json b/src/enm/study-NWKI-1b674a0a-fa78-48e5-b76c-147e56f8d237.json
new file mode 100644
index 0000000..47dd05b
--- /dev/null
+++ b/src/enm/study-NWKI-1b674a0a-fa78-48e5-b76c-147e56f8d237.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-1b674a0a-fa78-48e5-b76c-147e56f8d237",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fe8fe744-ea1f-3841-9a6d-f81be44651a8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn200546k",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1c0923d6-4d39-4523-b2a4-409698803b71.json b/src/enm/study-NWKI-1c0923d6-4d39-4523-b2a4-409698803b71.json
new file mode 100644
index 0000000..7065e2c
--- /dev/null
+++ b/src/enm/study-NWKI-1c0923d6-4d39-4523-b2a4-409698803b71.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-1c0923d6-4d39-4523-b2a4-409698803b71",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-144a9226-4b93-36a9-ba2d-6b6c4903357b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "Serum": {
+ "loValue": "cMEM"
+ },
+ "pH": {
+ "loValue": 7.88
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -11
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1c1ebeed-25e4-4fa7-aee3-053f238fd1da.json b/src/enm/study-NWKI-1c1ebeed-25e4-4fa7-aee3-053f238fd1da.json
new file mode 100644
index 0000000..6854a70
--- /dev/null
+++ b/src/enm/study-NWKI-1c1ebeed-25e4-4fa7-aee3-053f238fd1da.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-1c1ebeed-25e4-4fa7-aee3-053f238fd1da",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ee237892-6184-3016-92af-b41dc14e9f9b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 5.9
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1cca474e-5f3a-4a1c-adac-5e40e6554f00.json b/src/enm/study-NWKI-1cca474e-5f3a-4a1c-adac-5e40e6554f00.json
new file mode 100644
index 0000000..796bc89
--- /dev/null
+++ b/src/enm/study-NWKI-1cca474e-5f3a-4a1c-adac-5e40e6554f00.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-1cca474e-5f3a-4a1c-adac-5e40e6554f00",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 5,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1d0171f7-e65c-4da4-9b47-5218fb7f50ed.json b/src/enm/study-NWKI-1d0171f7-e65c-4da4-9b47-5218fb7f50ed.json
new file mode 100644
index 0000000..ce7da3f
--- /dev/null
+++ b/src/enm/study-NWKI-1d0171f7-e65c-4da4-9b47-5218fb7f50ed.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-1d0171f7-e65c-4da4-9b47-5218fb7f50ed",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9142c528-4a84-3566-b678-dc1eef7d22fe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "Shape",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Rutile"
+ },
+ "effects": [
+ {
+ "endpoint": "SHAPE",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Rutile"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1dbe71a3-fc3c-4dde-9e19-213824a4650e.json b/src/enm/study-NWKI-1dbe71a3-fc3c-4dde-9e19-213824a4650e.json
new file mode 100644
index 0000000..9ae41f7
--- /dev/null
+++ b/src/enm/study-NWKI-1dbe71a3-fc3c-4dde-9e19-213824a4650e.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-1dbe71a3-fc3c-4dde-9e19-213824a4650e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-34a6262c-7f25-3eea-9dd0-bf1e1df40ca9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SiO2"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "SiO2"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "APS_Coating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "APS"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "APS"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1ddab2f0-52a5-4c0a-835c-8644a8da7e30.json b/src/enm/study-NWKI-1ddab2f0-52a5-4c0a-835c-8644a8da7e30.json
new file mode 100644
index 0000000..0b97bc2
--- /dev/null
+++ b/src/enm/study-NWKI-1ddab2f0-52a5-4c0a-835c-8644a8da7e30.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-1ddab2f0-52a5-4c0a-835c-8644a8da7e30",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1df33a17-0117-4758-bb27-99b89f32effb.json b/src/enm/study-NWKI-1df33a17-0117-4758-bb27-99b89f32effb.json
new file mode 100644
index 0000000..1762dae
--- /dev/null
+++ b/src/enm/study-NWKI-1df33a17-0117-4758-bb27-99b89f32effb.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-1df33a17-0117-4758-bb27-99b89f32effb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1e3822cd-c251-4274-9ef5-193cb52cbf11.json b/src/enm/study-NWKI-1e3822cd-c251-4274-9ef5-193cb52cbf11.json
new file mode 100644
index 0000000..080476f
--- /dev/null
+++ b/src/enm/study-NWKI-1e3822cd-c251-4274-9ef5-193cb52cbf11.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-1e3822cd-c251-4274-9ef5-193cb52cbf11",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-37e2b8ec-0e57-3ed8-9afc-93a3030ee25f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 9.48,
+ "errorValue": 1.26
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1e3b4322-d062-4d9f-805c-55c6cbb1b3a5.json b/src/enm/study-NWKI-1e3b4322-d062-4d9f-805c-55c6cbb1b3a5.json
new file mode 100644
index 0000000..d576579
--- /dev/null
+++ b/src/enm/study-NWKI-1e3b4322-d062-4d9f-805c-55c6cbb1b3a5.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-1e3b4322-d062-4d9f-805c-55c6cbb1b3a5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-1d7c10cd-c2fe-3e95-94ec-2e4ee7099ec5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 21
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1e4e0b84-a846-4a46-b5ac-51b228cfed1c.json b/src/enm/study-NWKI-1e4e0b84-a846-4a46-b5ac-51b228cfed1c.json
new file mode 100644
index 0000000..f44534a
--- /dev/null
+++ b/src/enm/study-NWKI-1e4e0b84-a846-4a46-b5ac-51b228cfed1c.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-1e4e0b84-a846-4a46-b5ac-51b228cfed1c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-85b50517-fdea-3aa6-abbd-dd506393aaa5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 8,
+ "upQualifier": "<=",
+ "upValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1e7f5ba6-8146-40ef-a3f1-7d33628926a0.json b/src/enm/study-NWKI-1e7f5ba6-8146-40ef-a3f1-7d33628926a0.json
new file mode 100644
index 0000000..3a60c27
--- /dev/null
+++ b/src/enm/study-NWKI-1e7f5ba6-8146-40ef-a3f1-7d33628926a0.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-1e7f5ba6-8146-40ef-a3f1-7d33628926a0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-202b322d-51c9-3d73-a049-1e4019f8ddad"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 4.98,
+ "errorValue": 0.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1eeb4b23-e2b0-4653-bc3a-0e9a5a4fba3b.json b/src/enm/study-NWKI-1eeb4b23-e2b0-4653-bc3a-0e9a5a4fba3b.json
new file mode 100644
index 0000000..b206bd2
--- /dev/null
+++ b/src/enm/study-NWKI-1eeb4b23-e2b0-4653-bc3a-0e9a5a4fba3b.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-1eeb4b23-e2b0-4653-bc3a-0e9a5a4fba3b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9142c528-4a84-3566-b678-dc1eef7d22fe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1eef5dd4-73da-41fc-a306-1c736fcb69bb.json b/src/enm/study-NWKI-1eef5dd4-73da-41fc-a306-1c736fcb69bb.json
new file mode 100644
index 0000000..ae4e746
--- /dev/null
+++ b/src/enm/study-NWKI-1eef5dd4-73da-41fc-a306-1c736fcb69bb.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-1eef5dd4-73da-41fc-a306-1c736fcb69bb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e624f68e-2e00-30e4-b4bb-9e34383580cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 58
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1f25b708-f769-4dcf-8e2f-85bfac650cdd.json b/src/enm/study-NWKI-1f25b708-f769-4dcf-8e2f-85bfac650cdd.json
new file mode 100644
index 0000000..b1a68df
--- /dev/null
+++ b/src/enm/study-NWKI-1f25b708-f769-4dcf-8e2f-85bfac650cdd.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-1f25b708-f769-4dcf-8e2f-85bfac650cdd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ee237892-6184-3016-92af-b41dc14e9f9b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 74
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-1f71d69f-b2dd-4f8a-a4f7-0c2c2085058b.json b/src/enm/study-NWKI-1f71d69f-b2dd-4f8a-a4f7-0c2c2085058b.json
new file mode 100644
index 0000000..6cbae52
--- /dev/null
+++ b/src/enm/study-NWKI-1f71d69f-b2dd-4f8a-a4f7-0c2c2085058b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-1f71d69f-b2dd-4f8a-a4f7-0c2c2085058b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-202033a2-bd5b-4059-9c82-d95501402b12.json b/src/enm/study-NWKI-202033a2-bd5b-4059-9c82-d95501402b12.json
new file mode 100644
index 0000000..3ef0b7d
--- /dev/null
+++ b/src/enm/study-NWKI-202033a2-bd5b-4059-9c82-d95501402b12.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-202033a2-bd5b-4059-9c82-d95501402b12",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bbce341e-3e4d-37f9-a891-5462ada32180"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -50
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-203bc896-c8b2-4425-ba37-6c4ab168f360.json b/src/enm/study-NWKI-203bc896-c8b2-4425-ba37-6c4ab168f360.json
new file mode 100644
index 0000000..4942b29
--- /dev/null
+++ b/src/enm/study-NWKI-203bc896-c8b2-4425-ba37-6c4ab168f360.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-203bc896-c8b2-4425-ba37-6c4ab168f360",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e85f1dfb-0830-32a3-8394-c2cce810e3e2"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -57.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-204f8f8a-215e-4589-abe7-4fe42b8e2dc2.json b/src/enm/study-NWKI-204f8f8a-215e-4589-abe7-4fe42b8e2dc2.json
new file mode 100644
index 0000000..6878f1c
--- /dev/null
+++ b/src/enm/study-NWKI-204f8f8a-215e-4589-abe7-4fe42b8e2dc2.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-204f8f8a-215e-4589-abe7-4fe42b8e2dc2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e078849d-6137-33fc-b103-d458cb77184a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 7
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -22,
+ "errorValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-20706a1c-e61e-45e8-89f4-5253276b5155.json b/src/enm/study-NWKI-20706a1c-e61e-45e8-89f4-5253276b5155.json
new file mode 100644
index 0000000..d9b6431
--- /dev/null
+++ b/src/enm/study-NWKI-20706a1c-e61e-45e8-89f4-5253276b5155.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-20706a1c-e61e-45e8-89f4-5253276b5155",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ede00e9f-201f-33c9-9191-8dbf67fcf1b1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -16.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2099233e-b04b-4f9e-89f7-e25339b6cc90.json b/src/enm/study-NWKI-2099233e-b04b-4f9e-89f7-e25339b6cc90.json
new file mode 100644
index 0000000..023a010
--- /dev/null
+++ b/src/enm/study-NWKI-2099233e-b04b-4f9e-89f7-e25339b6cc90.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-2099233e-b04b-4f9e-89f7-e25339b6cc90",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-82c12809-d7af-3061-a531-1db744c521f0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "FITC"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "FITC"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-210d0bde-ac61-4498-92e9-e801eaed0325.json b/src/enm/study-NWKI-210d0bde-ac61-4498-92e9-e801eaed0325.json
new file mode 100644
index 0000000..850b0af
--- /dev/null
+++ b/src/enm/study-NWKI-210d0bde-ac61-4498-92e9-e801eaed0325.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-210d0bde-ac61-4498-92e9-e801eaed0325",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-959963fd-df22-35fb-b821-dd3d74dd40ce"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 180
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2141b230-1f6c-4cef-a0c0-beeb5ace4344.json b/src/enm/study-NWKI-2141b230-1f6c-4cef-a0c0-beeb5ace4344.json
new file mode 100644
index 0000000..7c148a6
--- /dev/null
+++ b/src/enm/study-NWKI-2141b230-1f6c-4cef-a0c0-beeb5ace4344.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-2141b230-1f6c-4cef-a0c0-beeb5ace4344",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-13b28611-c05b-325b-9e60-182c49b2a288"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 3,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 22
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2195cc6b-370b-478d-873c-de64afca349f.json b/src/enm/study-NWKI-2195cc6b-370b-478d-873c-de64afca349f.json
new file mode 100644
index 0000000..93a87a2
--- /dev/null
+++ b/src/enm/study-NWKI-2195cc6b-370b-478d-873c-de64afca349f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-2195cc6b-370b-478d-873c-de64afca349f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e5b618fd-dd48-3562-9a55-737ac7a68466"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-21c99803-9aea-440c-a82b-070a62e52524.json b/src/enm/study-NWKI-21c99803-9aea-440c-a82b-070a62e52524.json
new file mode 100644
index 0000000..475ef65
--- /dev/null
+++ b/src/enm/study-NWKI-21c99803-9aea-440c-a82b-070a62e52524.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-21c99803-9aea-440c-a82b-070a62e52524",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-df2f5618-fab4-3f50-a191-1eabaa999ff9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -74.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-22544826-1d70-4400-b767-f3b610284346.json b/src/enm/study-NWKI-22544826-1d70-4400-b767-f3b610284346.json
new file mode 100644
index 0000000..0eb1ce3
--- /dev/null
+++ b/src/enm/study-NWKI-22544826-1d70-4400-b767-f3b610284346.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-22544826-1d70-4400-b767-f3b610284346",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7efe542f-264c-3b57-a516-410b730df963"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 28
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-22642000-70c2-48a8-af04-e4b79a86d8e2.json b/src/enm/study-NWKI-22642000-70c2-48a8-af04-e4b79a86d8e2.json
new file mode 100644
index 0000000..9adc489
--- /dev/null
+++ b/src/enm/study-NWKI-22642000-70c2-48a8-af04-e4b79a86d8e2.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-22642000-70c2-48a8-af04-e4b79a86d8e2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4e021275-ae4e-3d24-bdb8-40c6d8d9d6fc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 33
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-226a98c7-2e60-4b2c-b3be-21fe83779526.json b/src/enm/study-NWKI-226a98c7-2e60-4b2c-b3be-21fe83779526.json
new file mode 100644
index 0000000..62aa920
--- /dev/null
+++ b/src/enm/study-NWKI-226a98c7-2e60-4b2c-b3be-21fe83779526.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-226a98c7-2e60-4b2c-b3be-21fe83779526",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-395bf212-b710-3385-9c23-715a7055b015"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 14
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-229f45c0-1354-4f72-a431-1c07d4f80d0b.json b/src/enm/study-NWKI-229f45c0-1354-4f72-a431-1c07d4f80d0b.json
new file mode 100644
index 0000000..be771d6
--- /dev/null
+++ b/src/enm/study-NWKI-229f45c0-1354-4f72-a431-1c07d4f80d0b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-229f45c0-1354-4f72-a431-1c07d4f80d0b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6821e372-3b17-3a56-8fac-f66115f24e5d"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
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+ "title": null,
+ "year": "0",
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+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 230
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-230e862e-2402-46e1-9e0a-5ecc057d6695.json b/src/enm/study-NWKI-230e862e-2402-46e1-9e0a-5ecc057d6695.json
new file mode 100644
index 0000000..bc07308
--- /dev/null
+++ b/src/enm/study-NWKI-230e862e-2402-46e1-9e0a-5ecc057d6695.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-230e862e-2402-46e1-9e0a-5ecc057d6695",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-905e44ef-3f7f-314d-add0-3e00439eaded"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2316021e-2bd1-407f-8db1-10d82a97ce85.json b/src/enm/study-NWKI-2316021e-2bd1-407f-8db1-10d82a97ce85.json
new file mode 100644
index 0000000..6ae5d16
--- /dev/null
+++ b/src/enm/study-NWKI-2316021e-2bd1-407f-8db1-10d82a97ce85.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-2316021e-2bd1-407f-8db1-10d82a97ce85",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0866f605-4cfb-32a2-a704-2cf2a8d3d9a6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 3.45
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-238893d9-0a10-4916-864a-3e29675d036d.json b/src/enm/study-NWKI-238893d9-0a10-4916-864a-3e29675d036d.json
new file mode 100644
index 0000000..82c43d7
--- /dev/null
+++ b/src/enm/study-NWKI-238893d9-0a10-4916-864a-3e29675d036d.json
@@ -0,0 +1,52 @@
+{
+ "uuid": "NWKI-238893d9-0a10-4916-864a-3e29675d036d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93603a1-8e0d-372a-8acf-48533b86ecb5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Concentration in culture medium",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_culture_medium",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/g",
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-23e79594-2966-47eb-90a7-adebb71c5a1a.json b/src/enm/study-NWKI-23e79594-2966-47eb-90a7-adebb71c5a1a.json
new file mode 100644
index 0000000..0a02ff0
--- /dev/null
+++ b/src/enm/study-NWKI-23e79594-2966-47eb-90a7-adebb71c5a1a.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-23e79594-2966-47eb-90a7-adebb71c5a1a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fc00f3ef-464d-32d3-9d12-7e78d25db6ce"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -43.4,
+ "errorValue": 0.89
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2434304e-6236-4c16-8c91-e2269ef64a82.json b/src/enm/study-NWKI-2434304e-6236-4c16-8c91-e2269ef64a82.json
new file mode 100644
index 0000000..b34d87e
--- /dev/null
+++ b/src/enm/study-NWKI-2434304e-6236-4c16-8c91-e2269ef64a82.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-2434304e-6236-4c16-8c91-e2269ef64a82",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c2075a8a-c7f2-31df-9d04-1cb096cdfece"
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+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "loQualifier": ">=",
+ "loValue": 10,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-24870f17-e19e-4d4e-a75e-fc1da15715f9.json b/src/enm/study-NWKI-24870f17-e19e-4d4e-a75e-fc1da15715f9.json
new file mode 100644
index 0000000..319aab2
--- /dev/null
+++ b/src/enm/study-NWKI-24870f17-e19e-4d4e-a75e-fc1da15715f9.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-24870f17-e19e-4d4e-a75e-fc1da15715f9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b19125a9-4499-3e0e-aa0c-7792401f4900"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "Remark": null,
+ "pH": null
+ },
+ "result": {
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+ "loValue": -4.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-24c0ce94-b9bb-4abf-9415-b52defdac67f.json b/src/enm/study-NWKI-24c0ce94-b9bb-4abf-9415-b52defdac67f.json
new file mode 100644
index 0000000..5c6b440
--- /dev/null
+++ b/src/enm/study-NWKI-24c0ce94-b9bb-4abf-9415-b52defdac67f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-24c0ce94-b9bb-4abf-9415-b52defdac67f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
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+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ },
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2575d442-a40e-444e-8653-bcb555e99baa.json b/src/enm/study-NWKI-2575d442-a40e-444e-8653-bcb555e99baa.json
new file mode 100644
index 0000000..ae799cc
--- /dev/null
+++ b/src/enm/study-NWKI-2575d442-a40e-444e-8653-bcb555e99baa.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-2575d442-a40e-444e-8653-bcb555e99baa",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-536c91ba-6cf8-3808-b611-f7d5830f5ed8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2011.587903",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ },
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+ },
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 24
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-25d1bdc0-b1e2-4d96-bfdc-f26099585f76.json b/src/enm/study-NWKI-25d1bdc0-b1e2-4d96-bfdc-f26099585f76.json
new file mode 100644
index 0000000..1ccffbd
--- /dev/null
+++ b/src/enm/study-NWKI-25d1bdc0-b1e2-4d96-bfdc-f26099585f76.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-25d1bdc0-b1e2-4d96-bfdc-f26099585f76",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-88767671-5631-3c93-8cfc-db0f48978e77"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "r_isUsedforClassification": "false",
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+ },
+ "interpretation": {
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+ },
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-26592811-15c2-4a2e-b684-e0849e59ad2d.json b/src/enm/study-NWKI-26592811-15c2-4a2e-b684-e0849e59ad2d.json
new file mode 100644
index 0000000..9c57c33
--- /dev/null
+++ b/src/enm/study-NWKI-26592811-15c2-4a2e-b684-e0849e59ad2d.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-26592811-15c2-4a2e-b684-e0849e59ad2d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7b6aae8a-bc39-3794-8140-8d409630c8bc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "conditions": {
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+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -59.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-26a723a1-8c78-49d7-a277-7008df754248.json b/src/enm/study-NWKI-26a723a1-8c78-49d7-a277-7008df754248.json
new file mode 100644
index 0000000..335beed
--- /dev/null
+++ b/src/enm/study-NWKI-26a723a1-8c78-49d7-a277-7008df754248.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-26a723a1-8c78-49d7-a277-7008df754248",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0a6e319e-71fc-37f7-b88d-fbda2e07ccc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 250,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-26b625c2-f38a-4a2f-b950-0e2c9f7191f7.json b/src/enm/study-NWKI-26b625c2-f38a-4a2f-b950-0e2c9f7191f7.json
new file mode 100644
index 0000000..3c91e19
--- /dev/null
+++ b/src/enm/study-NWKI-26b625c2-f38a-4a2f-b950-0e2c9f7191f7.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-26b625c2-f38a-4a2f-b950-0e2c9f7191f7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8667bfb7-a5da-3eb0-b9d7-86e2c8f06f19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-26e60e64-968f-4935-af8e-22052f7f09ba.json b/src/enm/study-NWKI-26e60e64-968f-4935-af8e-22052f7f09ba.json
new file mode 100644
index 0000000..258a435
--- /dev/null
+++ b/src/enm/study-NWKI-26e60e64-968f-4935-af8e-22052f7f09ba.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-26e60e64-968f-4935-af8e-22052f7f09ba",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b8a44a2-b835-3f75-903c-cf0a71a247c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 1,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 13
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-26e89dc8-26c3-48a9-ad65-a91dec14ef56.json b/src/enm/study-NWKI-26e89dc8-26c3-48a9-ad65-a91dec14ef56.json
new file mode 100644
index 0000000..63c4995
--- /dev/null
+++ b/src/enm/study-NWKI-26e89dc8-26c3-48a9-ad65-a91dec14ef56.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-26e89dc8-26c3-48a9-ad65-a91dec14ef56",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3ccff23c-b3d6-3614-aef4-4324be42804b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12.6,
+ "errorValue": 4.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2732ed2c-53c1-4fff-a4f0-b8772e472fcd.json b/src/enm/study-NWKI-2732ed2c-53c1-4fff-a4f0-b8772e472fcd.json
new file mode 100644
index 0000000..9f1fdab
--- /dev/null
+++ b/src/enm/study-NWKI-2732ed2c-53c1-4fff-a4f0-b8772e472fcd.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-2732ed2c-53c1-4fff-a4f0-b8772e472fcd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0455b6e1-5203-37bb-a98b-20460acceda1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 31
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-28032d42-937c-499a-bbe2-f4a1da0e89c2.json b/src/enm/study-NWKI-28032d42-937c-499a-bbe2-f4a1da0e89c2.json
new file mode 100644
index 0000000..d2de121
--- /dev/null
+++ b/src/enm/study-NWKI-28032d42-937c-499a-bbe2-f4a1da0e89c2.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-28032d42-937c-499a-bbe2-f4a1da0e89c2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-283a4d9f-1ddf-4550-9478-f419b7ff078a.json b/src/enm/study-NWKI-283a4d9f-1ddf-4550-9478-f419b7ff078a.json
new file mode 100644
index 0000000..1223b70
--- /dev/null
+++ b/src/enm/study-NWKI-283a4d9f-1ddf-4550-9478-f419b7ff078a.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-283a4d9f-1ddf-4550-9478-f419b7ff078a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3a3b2bcd-8284-37dc-a619-56ffbd7ebd68"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn2021056",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 23.4,
+ "errorValue": 4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2857ed00-21b0-4191-9628-dc163ac5ad49.json b/src/enm/study-NWKI-2857ed00-21b0-4191-9628-dc163ac5ad49.json
new file mode 100644
index 0000000..c7e5728
--- /dev/null
+++ b/src/enm/study-NWKI-2857ed00-21b0-4191-9628-dc163ac5ad49.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-2857ed00-21b0-4191-9628-dc163ac5ad49",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c2ab6def-8305-3b78-958a-4657b3363e11"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Isoelectric Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ISOELECTRIC POINT",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 5.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2874555f-a89b-4a19-a9b0-c8f5012f0d8b.json b/src/enm/study-NWKI-2874555f-a89b-4a19-a9b0-c8f5012f0d8b.json
new file mode 100644
index 0000000..905dfd4
--- /dev/null
+++ b/src/enm/study-NWKI-2874555f-a89b-4a19-a9b0-c8f5012f0d8b.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-2874555f-a89b-4a19-a9b0-c8f5012f0d8b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4f91db77-4cd0-3482-b989-571d2a9a4228"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn200546k",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 0.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-288222ad-ae6a-4ae7-ab7e-70ffd4433def.json b/src/enm/study-NWKI-288222ad-ae6a-4ae7-ab7e-70ffd4433def.json
new file mode 100644
index 0000000..90127e9
--- /dev/null
+++ b/src/enm/study-NWKI-288222ad-ae6a-4ae7-ab7e-70ffd4433def.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-288222ad-ae6a-4ae7-ab7e-70ffd4433def",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ad44f58f-8080-3017-9f8d-485fad044849"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DRhodamine-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Protamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Protamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-28a5b8c8-db90-40ff-89c5-cc9d3cbd176c.json b/src/enm/study-NWKI-28a5b8c8-db90-40ff-89c5-cc9d3cbd176c.json
new file mode 100644
index 0000000..f70dce3
--- /dev/null
+++ b/src/enm/study-NWKI-28a5b8c8-db90-40ff-89c5-cc9d3cbd176c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-28a5b8c8-db90-40ff-89c5-cc9d3cbd176c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 200,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-28d2fca5-1d49-4401-aa15-afbcddb14154.json b/src/enm/study-NWKI-28d2fca5-1d49-4401-aa15-afbcddb14154.json
new file mode 100644
index 0000000..100866e
--- /dev/null
+++ b/src/enm/study-NWKI-28d2fca5-1d49-4401-aa15-afbcddb14154.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-28d2fca5-1d49-4401-aa15-afbcddb14154",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5a049bb7-380d-3c89-9c39-f1310ed7b09d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 92,
+ "errorValue": 2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-28f4d696-5c08-414c-933a-4ab55dff076f.json b/src/enm/study-NWKI-28f4d696-5c08-414c-933a-4ab55dff076f.json
new file mode 100644
index 0000000..42d7c96
--- /dev/null
+++ b/src/enm/study-NWKI-28f4d696-5c08-414c-933a-4ab55dff076f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-28f4d696-5c08-414c-933a-4ab55dff076f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 200,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-29902ba0-0a8c-4a93-bd2f-1301b08b1278.json b/src/enm/study-NWKI-29902ba0-0a8c-4a93-bd2f-1301b08b1278.json
new file mode 100644
index 0000000..98f0a7b
--- /dev/null
+++ b/src/enm/study-NWKI-29902ba0-0a8c-4a93-bd2f-1301b08b1278.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-29902ba0-0a8c-4a93-bd2f-1301b08b1278",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-83a75181-9103-3ef9-aec7-fa38074580f6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 3.37,
+ "errorValue": 0.57
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-299853db-1973-4a85-9ae2-f85e7cd5c8f1.json b/src/enm/study-NWKI-299853db-1973-4a85-9ae2-f85e7cd5c8f1.json
new file mode 100644
index 0000000..1b80639
--- /dev/null
+++ b/src/enm/study-NWKI-299853db-1973-4a85-9ae2-f85e7cd5c8f1.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-299853db-1973-4a85-9ae2-f85e7cd5c8f1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ede00e9f-201f-33c9-9191-8dbf67fcf1b1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "CdSe"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "CdSe"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH-2DAmphPolymer"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Amphiphillic_Polymer"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Amphiphillic_Polymer"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-299b892c-97fc-43f6-985c-768a7c84f287.json b/src/enm/study-NWKI-299b892c-97fc-43f6-985c-768a7c84f287.json
new file mode 100644
index 0000000..0033a71
--- /dev/null
+++ b/src/enm/study-NWKI-299b892c-97fc-43f6-985c-768a7c84f287.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-299b892c-97fc-43f6-985c-768a7c84f287",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5454d5cb-1033-3d6f-a31e-038752525533"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 108
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-299d8d27-4b6a-4b9c-a500-28ede35d570e.json b/src/enm/study-NWKI-299d8d27-4b6a-4b9c-a500-28ede35d570e.json
new file mode 100644
index 0000000..c720263
--- /dev/null
+++ b/src/enm/study-NWKI-299d8d27-4b6a-4b9c-a500-28ede35d570e.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-299d8d27-4b6a-4b9c-a500-28ede35d570e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3db8eb74-b206-31ad-8c1b-3569703c47cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 97
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-299db44e-27a2-4aba-9c25-a1ae9a9e2959.json b/src/enm/study-NWKI-299db44e-27a2-4aba-9c25-a1ae9a9e2959.json
new file mode 100644
index 0000000..17ce5ef
--- /dev/null
+++ b/src/enm/study-NWKI-299db44e-27a2-4aba-9c25-a1ae9a9e2959.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-299db44e-27a2-4aba-9c25-a1ae9a9e2959",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d8f70c6c-3496-3ad3-8ab3-e4f08a178d30"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 2000,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-29bb615b-97c3-48e8-b04c-9b3c0e6d3dc2.json b/src/enm/study-NWKI-29bb615b-97c3-48e8-b04c-9b3c0e6d3dc2.json
new file mode 100644
index 0000000..a3c44b3
--- /dev/null
+++ b/src/enm/study-NWKI-29bb615b-97c3-48e8-b04c-9b3c0e6d3dc2.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-29bb615b-97c3-48e8-b04c-9b3c0e6d3dc2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-29e445cd-20bf-491f-9be4-03a72f03db02.json b/src/enm/study-NWKI-29e445cd-20bf-491f-9be4-03a72f03db02.json
new file mode 100644
index 0000000..e0754a6
--- /dev/null
+++ b/src/enm/study-NWKI-29e445cd-20bf-491f-9be4-03a72f03db02.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-29e445cd-20bf-491f-9be4-03a72f03db02",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4832de65-5a92-3849-8061-729a2d83017e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 320
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2a0a9364-2a37-40e6-9608-9a035483cef9.json b/src/enm/study-NWKI-2a0a9364-2a37-40e6-9608-9a035483cef9.json
new file mode 100644
index 0000000..9241b9d
--- /dev/null
+++ b/src/enm/study-NWKI-2a0a9364-2a37-40e6-9608-9a035483cef9.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-2a0a9364-2a37-40e6-9608-9a035483cef9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-905e44ef-3f7f-314d-add0-3e00439eaded"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 3.45
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2a6c5f39-8eec-4b37-ae56-7f0b1f2fa52f.json b/src/enm/study-NWKI-2a6c5f39-8eec-4b37-ae56-7f0b1f2fa52f.json
new file mode 100644
index 0000000..41eb95e
--- /dev/null
+++ b/src/enm/study-NWKI-2a6c5f39-8eec-4b37-ae56-7f0b1f2fa52f.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-2a6c5f39-8eec-4b37-ae56-7f0b1f2fa52f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3068a619-f77c-3f33-848a-7b4248f6c52c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -48.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2a93ff70-da43-42ff-8333-ae1552a0e9fa.json b/src/enm/study-NWKI-2a93ff70-da43-42ff-8333-ae1552a0e9fa.json
new file mode 100644
index 0000000..3618730
--- /dev/null
+++ b/src/enm/study-NWKI-2a93ff70-da43-42ff-8333-ae1552a0e9fa.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-2a93ff70-da43-42ff-8333-ae1552a0e9fa",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 50,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2ac5ee28-7aa5-44eb-be7a-8cb8b102c3b5.json b/src/enm/study-NWKI-2ac5ee28-7aa5-44eb-be7a-8cb8b102c3b5.json
new file mode 100644
index 0000000..c5c2b26
--- /dev/null
+++ b/src/enm/study-NWKI-2ac5ee28-7aa5-44eb-be7a-8cb8b102c3b5.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-2ac5ee28-7aa5-44eb-be7a-8cb8b102c3b5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-57a03b07-0bb6-306c-ba30-71d5bc626385"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.soilbio.2013.01.016",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loQualifier": ">=",
+ "loValue": 40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2b0e084f-2f89-41f0-a01c-72d89c23f175.json b/src/enm/study-NWKI-2b0e084f-2f89-41f0-a01c-72d89c23f175.json
new file mode 100644
index 0000000..9a24d6b
--- /dev/null
+++ b/src/enm/study-NWKI-2b0e084f-2f89-41f0-a01c-72d89c23f175.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-2b0e084f-2f89-41f0-a01c-72d89c23f175",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6cab56b4-69d9-36e0-8c17-f467d08b2555"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH-2DPVA"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "O=CO[H]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "COOH"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2bacd054-36df-4ea5-810c-0de08179cbf3.json b/src/enm/study-NWKI-2bacd054-36df-4ea5-810c-0de08179cbf3.json
new file mode 100644
index 0000000..c5653b6
--- /dev/null
+++ b/src/enm/study-NWKI-2bacd054-36df-4ea5-810c-0de08179cbf3.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-2bacd054-36df-4ea5-810c-0de08179cbf3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3481f716-18fa-39b3-aa54-4acb67877194"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DGlycine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2bf27a2e-1693-4d61-9d4f-85904590957c.json b/src/enm/study-NWKI-2bf27a2e-1693-4d61-9d4f-85904590957c.json
new file mode 100644
index 0000000..28183ba
--- /dev/null
+++ b/src/enm/study-NWKI-2bf27a2e-1693-4d61-9d4f-85904590957c.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-2bf27a2e-1693-4d61-9d4f-85904590957c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b4bd899e-c57e-3aaa-bf6f-54ec8ebd6ab5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 50
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2c19a322-a657-435a-9de7-b768efa0de5d.json b/src/enm/study-NWKI-2c19a322-a657-435a-9de7-b768efa0de5d.json
new file mode 100644
index 0000000..773df98
--- /dev/null
+++ b/src/enm/study-NWKI-2c19a322-a657-435a-9de7-b768efa0de5d.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-2c19a322-a657-435a-9de7-b768efa0de5d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-13b28611-c05b-325b-9e60-182c49b2a288"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 80,
+ "upQualifier": "<=",
+ "upValue": 150
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2c886612-ba50-4458-b3dc-b0e9da77ee63.json b/src/enm/study-NWKI-2c886612-ba50-4458-b3dc-b0e9da77ee63.json
new file mode 100644
index 0000000..995afa7
--- /dev/null
+++ b/src/enm/study-NWKI-2c886612-ba50-4458-b3dc-b0e9da77ee63.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-2c886612-ba50-4458-b3dc-b0e9da77ee63",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a4b3e23-3327-3421-b20a-2e71939b44b1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DGlutamicAcid"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "FITC"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "FITC"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2caa1583-ad03-4f9c-adb2-d8fb7dd299f3.json b/src/enm/study-NWKI-2caa1583-ad03-4f9c-adb2-d8fb7dd299f3.json
new file mode 100644
index 0000000..8a93f57
--- /dev/null
+++ b/src/enm/study-NWKI-2caa1583-ad03-4f9c-adb2-d8fb7dd299f3.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-2caa1583-ad03-4f9c-adb2-d8fb7dd299f3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3fb9be70-8c15-3b78-94e7-5c3c88799818"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -4.22
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2da0ea19-ca30-4b3f-b1f0-19a5790c1621.json b/src/enm/study-NWKI-2da0ea19-ca30-4b3f-b1f0-19a5790c1621.json
new file mode 100644
index 0000000..0ff02d0
--- /dev/null
+++ b/src/enm/study-NWKI-2da0ea19-ca30-4b3f-b1f0-19a5790c1621.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-2da0ea19-ca30-4b3f-b1f0-19a5790c1621",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a968835-50ab-33df-bf5e-42de32d01c15"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 8
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2dbb5798-e811-4968-9496-da98b03ad991.json b/src/enm/study-NWKI-2dbb5798-e811-4968-9496-da98b03ad991.json
new file mode 100644
index 0000000..ea8d739
--- /dev/null
+++ b/src/enm/study-NWKI-2dbb5798-e811-4968-9496-da98b03ad991.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-2dbb5798-e811-4968-9496-da98b03ad991",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 150,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2def1a31-61ca-499f-bdf0-374670910a81.json b/src/enm/study-NWKI-2def1a31-61ca-499f-bdf0-374670910a81.json
new file mode 100644
index 0000000..6476a17
--- /dev/null
+++ b/src/enm/study-NWKI-2def1a31-61ca-499f-bdf0-374670910a81.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-2def1a31-61ca-499f-bdf0-374670910a81",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a33b26f0-2fc7-3aa1-9dd6-27380f725bfe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2dfbca11-00fc-49c9-876b-6be628025350.json b/src/enm/study-NWKI-2dfbca11-00fc-49c9-876b-6be628025350.json
new file mode 100644
index 0000000..e94698e
--- /dev/null
+++ b/src/enm/study-NWKI-2dfbca11-00fc-49c9-876b-6be628025350.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-2dfbca11-00fc-49c9-876b-6be628025350",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-155bb96c-2d7e-384d-b55d-45856eeda386"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2e105bec-9f2f-456d-85ad-0f01e08dacb6.json b/src/enm/study-NWKI-2e105bec-9f2f-456d-85ad-0f01e08dacb6.json
new file mode 100644
index 0000000..d11f11c
--- /dev/null
+++ b/src/enm/study-NWKI-2e105bec-9f2f-456d-85ad-0f01e08dacb6.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-2e105bec-9f2f-456d-85ad-0f01e08dacb6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93603a1-8e0d-372a-8acf-48533b86ecb5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 10,
+ "unit": "m"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2e9983eb-ea2c-4fbf-a1a3-4fedbc871d87.json b/src/enm/study-NWKI-2e9983eb-ea2c-4fbf-a1a3-4fedbc871d87.json
new file mode 100644
index 0000000..2d7b0f2
--- /dev/null
+++ b/src/enm/study-NWKI-2e9983eb-ea2c-4fbf-a1a3-4fedbc871d87.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-2e9983eb-ea2c-4fbf-a1a3-4fedbc871d87",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0494174f-9fc2-3296-8ffb-4fadaceb0348"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 617,
+ "errorValue": 27
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2f1f62b2-8f0f-422f-a2ae-1ad5229a1fe1.json b/src/enm/study-NWKI-2f1f62b2-8f0f-422f-a2ae-1ad5229a1fe1.json
new file mode 100644
index 0000000..f2931cb
--- /dev/null
+++ b/src/enm/study-NWKI-2f1f62b2-8f0f-422f-a2ae-1ad5229a1fe1.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-2f1f62b2-8f0f-422f-a2ae-1ad5229a1fe1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2390517f-b763-3850-b1b4-6e50fee63829"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.81
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2f252609-ec14-4014-b4ff-5f062deb4fdd.json b/src/enm/study-NWKI-2f252609-ec14-4014-b4ff-5f062deb4fdd.json
new file mode 100644
index 0000000..daf43c4
--- /dev/null
+++ b/src/enm/study-NWKI-2f252609-ec14-4014-b4ff-5f062deb4fdd.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-2f252609-ec14-4014-b4ff-5f062deb4fdd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2f590895-a505-4ac2-890c-491a0a2f4eeb.json b/src/enm/study-NWKI-2f590895-a505-4ac2-890c-491a0a2f4eeb.json
new file mode 100644
index 0000000..97151d5
--- /dev/null
+++ b/src/enm/study-NWKI-2f590895-a505-4ac2-890c-491a0a2f4eeb.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-2f590895-a505-4ac2-890c-491a0a2f4eeb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-458c2d5a-53f0-3c65-81eb-6fb5d128db59"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 378,
+ "errorValue": 70
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-2f67c03b-e137-475e-b8e1-f7147b2f0734.json b/src/enm/study-NWKI-2f67c03b-e137-475e-b8e1-f7147b2f0734.json
new file mode 100644
index 0000000..d5e8143
--- /dev/null
+++ b/src/enm/study-NWKI-2f67c03b-e137-475e-b8e1-f7147b2f0734.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-2f67c03b-e137-475e-b8e1-f7147b2f0734",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c012600e-ca8e-31db-a7a8-d9f6a74e2464"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-304bf941-2d4e-4069-bc64-c2ca8b68338a.json b/src/enm/study-NWKI-304bf941-2d4e-4069-bc64-c2ca8b68338a.json
new file mode 100644
index 0000000..0ee034b
--- /dev/null
+++ b/src/enm/study-NWKI-304bf941-2d4e-4069-bc64-c2ca8b68338a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-304bf941-2d4e-4069-bc64-c2ca8b68338a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-11ae9232-1521-31d6-9466-c902c43d94fe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 28
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-308b284b-e2ae-4f73-a350-d0deb35cb0b2.json b/src/enm/study-NWKI-308b284b-e2ae-4f73-a350-d0deb35cb0b2.json
new file mode 100644
index 0000000..63d0d97
--- /dev/null
+++ b/src/enm/study-NWKI-308b284b-e2ae-4f73-a350-d0deb35cb0b2.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-308b284b-e2ae-4f73-a350-d0deb35cb0b2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8196e92b-c46d-3c14-9410-e87992810710"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 60
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-30a5f8ec-7758-4f6e-bf77-fc75108fd1fb.json b/src/enm/study-NWKI-30a5f8ec-7758-4f6e-bf77-fc75108fd1fb.json
new file mode 100644
index 0000000..c73f6dc
--- /dev/null
+++ b/src/enm/study-NWKI-30a5f8ec-7758-4f6e-bf77-fc75108fd1fb.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-30a5f8ec-7758-4f6e-bf77-fc75108fd1fb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ad44f58f-8080-3017-9f8d-485fad044849"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 31
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-30d9478c-941f-4174-bdf0-48841c418f1a.json b/src/enm/study-NWKI-30d9478c-941f-4174-bdf0-48841c418f1a.json
new file mode 100644
index 0000000..7cb14bc
--- /dev/null
+++ b/src/enm/study-NWKI-30d9478c-941f-4174-bdf0-48841c418f1a.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-30d9478c-941f-4174-bdf0-48841c418f1a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-315aa68b-5450-4657-8545-0a894a6c662e.json b/src/enm/study-NWKI-315aa68b-5450-4657-8545-0a894a6c662e.json
new file mode 100644
index 0000000..db1f49b
--- /dev/null
+++ b/src/enm/study-NWKI-315aa68b-5450-4657-8545-0a894a6c662e.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-315aa68b-5450-4657-8545-0a894a6c662e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-984a9c7f-2372-3b8f-9ff5-93a9f94f2eb7"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 855,
+ "errorValue": 37
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-316b62f2-31bc-4b10-a967-48c9be7cd6be.json b/src/enm/study-NWKI-316b62f2-31bc-4b10-a967-48c9be7cd6be.json
new file mode 100644
index 0000000..30cb573
--- /dev/null
+++ b/src/enm/study-NWKI-316b62f2-31bc-4b10-a967-48c9be7cd6be.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-316b62f2-31bc-4b10-a967-48c9be7cd6be",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-56d49cc3-4a76-354b-9a77-4b2ecb2dbef0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-31812e13-570d-4bf0-8c6d-5635218c8fb5.json b/src/enm/study-NWKI-31812e13-570d-4bf0-8c6d-5635218c8fb5.json
new file mode 100644
index 0000000..d616a39
--- /dev/null
+++ b/src/enm/study-NWKI-31812e13-570d-4bf0-8c6d-5635218c8fb5.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-31812e13-570d-4bf0-8c6d-5635218c8fb5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9fb12a3a-3a26-3f95-82ed-371f58d92dfe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 205,
+ "errorValue": 20.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-318a63ca-3312-41f8-8896-0f20a7cc8b10.json b/src/enm/study-NWKI-318a63ca-3312-41f8-8896-0f20a7cc8b10.json
new file mode 100644
index 0000000..05b8f43
--- /dev/null
+++ b/src/enm/study-NWKI-318a63ca-3312-41f8-8896-0f20a7cc8b10.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-318a63ca-3312-41f8-8896-0f20a7cc8b10",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cad5bf58-cc90-33e5-88bb-bad4c9f9fe9e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DCY5"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3225cb74-4a8d-4395-b54e-4e82b7314e3a.json b/src/enm/study-NWKI-3225cb74-4a8d-4395-b54e-4e82b7314e3a.json
new file mode 100644
index 0000000..373adeb
--- /dev/null
+++ b/src/enm/study-NWKI-3225cb74-4a8d-4395-b54e-4e82b7314e3a.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-3225cb74-4a8d-4395-b54e-4e82b7314e3a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-99fe068d-e343-35f8-9cc9-06c3a3cf8e22"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 51.5,
+ "errorValue": 7.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-327518e0-53d1-4c5c-9c94-a80e3d43f535.json b/src/enm/study-NWKI-327518e0-53d1-4c5c-9c94-a80e3d43f535.json
new file mode 100644
index 0000000..13896a0
--- /dev/null
+++ b/src/enm/study-NWKI-327518e0-53d1-4c5c-9c94-a80e3d43f535.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-327518e0-53d1-4c5c-9c94-a80e3d43f535",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ea2bb63b-fd2a-32c2-a41a-d0280abaf29f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 3.51
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-32b90f7e-f71d-4748-8903-1afe74263c9b.json b/src/enm/study-NWKI-32b90f7e-f71d-4748-8903-1afe74263c9b.json
new file mode 100644
index 0000000..7566b1b
--- /dev/null
+++ b/src/enm/study-NWKI-32b90f7e-f71d-4748-8903-1afe74263c9b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-32b90f7e-f71d-4748-8903-1afe74263c9b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 150,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-32ed71dd-3d4e-4bbb-9ca1-dcf617d6a280.json b/src/enm/study-NWKI-32ed71dd-3d4e-4bbb-9ca1-dcf617d6a280.json
new file mode 100644
index 0000000..b501dc2
--- /dev/null
+++ b/src/enm/study-NWKI-32ed71dd-3d4e-4bbb-9ca1-dcf617d6a280.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-32ed71dd-3d4e-4bbb-9ca1-dcf617d6a280",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-35426c83-c6fb-4f54-b3a5-380884d1bafa.json b/src/enm/study-NWKI-35426c83-c6fb-4f54-b3a5-380884d1bafa.json
new file mode 100644
index 0000000..7faf65a
--- /dev/null
+++ b/src/enm/study-NWKI-35426c83-c6fb-4f54-b3a5-380884d1bafa.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-35426c83-c6fb-4f54-b3a5-380884d1bafa",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1.6,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-35624d25-940c-4ca1-8342-b3a41a43323f.json b/src/enm/study-NWKI-35624d25-940c-4ca1-8342-b3a41a43323f.json
new file mode 100644
index 0000000..4861fc9
--- /dev/null
+++ b/src/enm/study-NWKI-35624d25-940c-4ca1-8342-b3a41a43323f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-35624d25-940c-4ca1-8342-b3a41a43323f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e24378b0-c0bb-365a-b533-e8f303681c2e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2011.587903",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 142
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-35e268e0-2d8f-4904-8a92-34016c907cf4.json b/src/enm/study-NWKI-35e268e0-2d8f-4904-8a92-34016c907cf4.json
new file mode 100644
index 0000000..4f7b72f
--- /dev/null
+++ b/src/enm/study-NWKI-35e268e0-2d8f-4904-8a92-34016c907cf4.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-35e268e0-2d8f-4904-8a92-34016c907cf4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-895a506b-c331-3576-bf9e-cbcde5822c11"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "sfMEM"
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 63
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-35e8ff01-974c-41f8-8129-48cc4a203144.json b/src/enm/study-NWKI-35e8ff01-974c-41f8-8129-48cc4a203144.json
new file mode 100644
index 0000000..2d047d8
--- /dev/null
+++ b/src/enm/study-NWKI-35e8ff01-974c-41f8-8129-48cc4a203144.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-35e8ff01-974c-41f8-8129-48cc4a203144",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b1b44fa-70c1-3034-9c4b-7efb334762e0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 22
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-36c3f16a-3250-40ca-b265-e0b23202a5ce.json b/src/enm/study-NWKI-36c3f16a-3250-40ca-b265-e0b23202a5ce.json
new file mode 100644
index 0000000..0d4a060
--- /dev/null
+++ b/src/enm/study-NWKI-36c3f16a-3250-40ca-b265-e0b23202a5ce.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-36c3f16a-3250-40ca-b265-e0b23202a5ce",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8c5b9350-2c03-3173-9615-cabfbe6929c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 14
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-378cd8d0-d9a4-4700-8fda-0c27fb863dd4.json b/src/enm/study-NWKI-378cd8d0-d9a4-4700-8fda-0c27fb863dd4.json
new file mode 100644
index 0000000..47f8a34
--- /dev/null
+++ b/src/enm/study-NWKI-378cd8d0-d9a4-4700-8fda-0c27fb863dd4.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-378cd8d0-d9a4-4700-8fda-0c27fb863dd4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3811859b-4696-4635-8556-d86a07808072.json b/src/enm/study-NWKI-3811859b-4696-4635-8556-d86a07808072.json
new file mode 100644
index 0000000..beeb5a8
--- /dev/null
+++ b/src/enm/study-NWKI-3811859b-4696-4635-8556-d86a07808072.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-3811859b-4696-4635-8556-d86a07808072",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-88767671-5631-3c93-8cfc-db0f48978e77"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.87
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-381ff327-4da8-4176-8e57-fa95e52c570d.json b/src/enm/study-NWKI-381ff327-4da8-4176-8e57-fa95e52c570d.json
new file mode 100644
index 0000000..842678a
--- /dev/null
+++ b/src/enm/study-NWKI-381ff327-4da8-4176-8e57-fa95e52c570d.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-381ff327-4da8-4176-8e57-fa95e52c570d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-666817c2-87cb-3826-92f8-e79a7b37957d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "Shape",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Rutile"
+ },
+ "effects": [
+ {
+ "endpoint": "SHAPE",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Rutile"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3825451c-f85b-45a4-b830-199dcdb54aff.json b/src/enm/study-NWKI-3825451c-f85b-45a4-b830-199dcdb54aff.json
new file mode 100644
index 0000000..9920380
--- /dev/null
+++ b/src/enm/study-NWKI-3825451c-f85b-45a4-b830-199dcdb54aff.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-3825451c-f85b-45a4-b830-199dcdb54aff",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ec00c05f-0b35-3c5a-b16f-7a3560213764"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFTIC-2DSI"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Succinimidyl_Iodoacatate"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "C1CC(=O)N(C1=O)OC(=O)CI"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Succinimidyl_Iodoacatate"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-38294160-f5b6-4f9e-9ac2-f795767b42ea.json b/src/enm/study-NWKI-38294160-f5b6-4f9e-9ac2-f795767b42ea.json
new file mode 100644
index 0000000..7d7518d
--- /dev/null
+++ b/src/enm/study-NWKI-38294160-f5b6-4f9e-9ac2-f795767b42ea.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-38294160-f5b6-4f9e-9ac2-f795767b42ea",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-02981dd4-b7d0-34c8-a0ab-dd19a5a40865"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -13.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3941a35c-3571-4154-a31d-354556e86453.json b/src/enm/study-NWKI-3941a35c-3571-4154-a31d-354556e86453.json
new file mode 100644
index 0000000..29b0ed8
--- /dev/null
+++ b/src/enm/study-NWKI-3941a35c-3571-4154-a31d-354556e86453.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-3941a35c-3571-4154-a31d-354556e86453",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e866549e-38cf-3b98-a0b1-a483e275d261"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "Shape",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Spherical"
+ },
+ "effects": [
+ {
+ "endpoint": "SHAPE",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Spherical"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-395ec63b-e8b2-420c-9731-683645537ff6.json b/src/enm/study-NWKI-395ec63b-e8b2-420c-9731-683645537ff6.json
new file mode 100644
index 0000000..4a191d8
--- /dev/null
+++ b/src/enm/study-NWKI-395ec63b-e8b2-420c-9731-683645537ff6.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-395ec63b-e8b2-420c-9731-683645537ff6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8090df08-f0f9-3c2f-8769-b51c2adaffc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -29.4,
+ "errorValue": 5.62
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3988370f-7a39-4e7a-b55f-c15c3587bbec.json b/src/enm/study-NWKI-3988370f-7a39-4e7a-b55f-c15c3587bbec.json
new file mode 100644
index 0000000..31117ff
--- /dev/null
+++ b/src/enm/study-NWKI-3988370f-7a39-4e7a-b55f-c15c3587bbec.json
@@ -0,0 +1,72 @@
+{
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+ "name": "NanoWiki"
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+ "title": "4.30 Nanomaterial surface chemistry"
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+ "endpoint": "Unknown",
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+ ""
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+ },
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+ "textValue": "VT680"
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+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3a1fc931-dd5d-43d5-9d84-734b4307e1b6.json b/src/enm/study-NWKI-3a1fc931-dd5d-43d5-9d84-734b4307e1b6.json
new file mode 100644
index 0000000..e3461c2
--- /dev/null
+++ b/src/enm/study-NWKI-3a1fc931-dd5d-43d5-9d84-734b4307e1b6.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-3a1fc931-dd5d-43d5-9d84-734b4307e1b6",
+ "owner": {
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+ "uuid": "NWKI-0fef8d9c-b0c4-3e41-88d0-b85cd538a796"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
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+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
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+ },
+ "interpretation": {
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+ },
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+ "endpoint": "Log_Reciprocal_EC50",
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+ "loValue": 1.74
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3a9bf0cc-82f7-4340-b6b5-f908a9f7089c.json b/src/enm/study-NWKI-3a9bf0cc-82f7-4340-b6b5-f908a9f7089c.json
new file mode 100644
index 0000000..ed2c837
--- /dev/null
+++ b/src/enm/study-NWKI-3a9bf0cc-82f7-4340-b6b5-f908a9f7089c.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-3a9bf0cc-82f7-4340-b6b5-f908a9f7089c",
+ "owner": {
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+ "uuid": "NWKI-f40bfb8a-1280-35a2-866c-42b5a3ce13e7"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
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+ "year": "0",
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
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+ "guideline": [
+ ""
+ ]
+ },
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+ },
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+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3ab749d1-ef02-4896-884f-3a95ed8c5601.json b/src/enm/study-NWKI-3ab749d1-ef02-4896-884f-3a95ed8c5601.json
new file mode 100644
index 0000000..2c98cec
--- /dev/null
+++ b/src/enm/study-NWKI-3ab749d1-ef02-4896-884f-3a95ed8c5601.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-3ab749d1-ef02-4896-884f-3a95ed8c5601",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bbb67d89-eaff-38ab-ba4f-403bfb064a0c"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ },
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
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+}
diff --git a/src/enm/study-NWKI-3ae0012d-9a09-4654-97db-cf210abc97cb.json b/src/enm/study-NWKI-3ae0012d-9a09-4654-97db-cf210abc97cb.json
new file mode 100644
index 0000000..7666cfa
--- /dev/null
+++ b/src/enm/study-NWKI-3ae0012d-9a09-4654-97db-cf210abc97cb.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-3ae0012d-9a09-4654-97db-cf210abc97cb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-69b604fb-e892-31ba-a6f5-feb6cb04effb"
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+ "name": "NanoWiki"
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+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
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+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
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+ "textValue": "Fe3O4"
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+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ }
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+ "textValue": "AlexaFluor750"
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diff --git a/src/enm/study-NWKI-3bcc3eab-4c4a-4e2c-bfe9-889d5697cd00.json b/src/enm/study-NWKI-3bcc3eab-4c4a-4e2c-bfe9-889d5697cd00.json
new file mode 100644
index 0000000..ee2ed3d
--- /dev/null
+++ b/src/enm/study-NWKI-3bcc3eab-4c4a-4e2c-bfe9-889d5697cd00.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-3bcc3eab-4c4a-4e2c-bfe9-889d5697cd00",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e834e3f1-8c0d-319e-9bac-21c613bdccd0"
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+ "name": "NanoWiki"
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
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+ },
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+ "textValue": "Ag"
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+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "loValue": "TMATCoating"
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+ "ELEMENT_OR_GROUP": {
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+ "loValue": "SCC[N+](C)(C)C.[I-]"
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+ }
+ },
+ "result": {
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+ "textValue": "TMAT"
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+ }
+ ]
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diff --git a/src/enm/study-NWKI-3c3b9140-6c10-4a7a-a15e-13f9f9b006a5.json b/src/enm/study-NWKI-3c3b9140-6c10-4a7a-a15e-13f9f9b006a5.json
new file mode 100644
index 0000000..12c6e89
--- /dev/null
+++ b/src/enm/study-NWKI-3c3b9140-6c10-4a7a-a15e-13f9f9b006a5.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-3c3b9140-6c10-4a7a-a15e-13f9f9b006a5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-05ce8604-4efc-376b-a88f-338a90465243"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2015.1017022",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Diameter",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ },
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+ },
+ "effects": [
+ {
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+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 74,
+ "errorValue": 28
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3c42f5fc-0968-4903-98b7-73cfc8889d94.json b/src/enm/study-NWKI-3c42f5fc-0968-4903-98b7-73cfc8889d94.json
new file mode 100644
index 0000000..6550c19
--- /dev/null
+++ b/src/enm/study-NWKI-3c42f5fc-0968-4903-98b7-73cfc8889d94.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-3c42f5fc-0968-4903-98b7-73cfc8889d94",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3c50948f-f6fe-4734-b2ae-3e3b0442384b.json b/src/enm/study-NWKI-3c50948f-f6fe-4734-b2ae-3e3b0442384b.json
new file mode 100644
index 0000000..0687593
--- /dev/null
+++ b/src/enm/study-NWKI-3c50948f-f6fe-4734-b2ae-3e3b0442384b.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-3c50948f-f6fe-4734-b2ae-3e3b0442384b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-85b50517-fdea-3aa6-abbd-dd506393aaa5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 75
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3c8f8896-6dea-4451-a11f-3c965363955c.json b/src/enm/study-NWKI-3c8f8896-6dea-4451-a11f-3c965363955c.json
new file mode 100644
index 0000000..bfff265
--- /dev/null
+++ b/src/enm/study-NWKI-3c8f8896-6dea-4451-a11f-3c965363955c.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-3c8f8896-6dea-4451-a11f-3c965363955c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-61c73e33-28ab-3387-8cdf-cb7c135fb06c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "result": {
+ "unit": "nm",
+ "loValue": 18.3,
+ "errorValue": 6.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3d0e9cd5-4ad6-4505-a94c-5ef922462050.json b/src/enm/study-NWKI-3d0e9cd5-4ad6-4505-a94c-5ef922462050.json
new file mode 100644
index 0000000..e68b88d
--- /dev/null
+++ b/src/enm/study-NWKI-3d0e9cd5-4ad6-4505-a94c-5ef922462050.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-3d0e9cd5-4ad6-4505-a94c-5ef922462050",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bc434442-e632-3829-be8d-64df1c9b70d3"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1063/1.2061873",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3d3bad37-27f6-4d18-bc7a-fc2a6010717f.json b/src/enm/study-NWKI-3d3bad37-27f6-4d18-bc7a-fc2a6010717f.json
new file mode 100644
index 0000000..fcd6084
--- /dev/null
+++ b/src/enm/study-NWKI-3d3bad37-27f6-4d18-bc7a-fc2a6010717f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-3d3bad37-27f6-4d18-bc7a-fc2a6010717f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f3be029d-68f6-310a-87a4-ceffee1b4eda"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 160
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3d42e721-069b-435e-8bcc-7198efc7225e.json b/src/enm/study-NWKI-3d42e721-069b-435e-8bcc-7198efc7225e.json
new file mode 100644
index 0000000..4f7dfdb
--- /dev/null
+++ b/src/enm/study-NWKI-3d42e721-069b-435e-8bcc-7198efc7225e.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-3d42e721-069b-435e-8bcc-7198efc7225e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0d776d00-aec4-3a75-9eb3-453909fc50ed"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -9.23
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3e4eb704-bc7a-4867-af2f-58c5bc77d35f.json b/src/enm/study-NWKI-3e4eb704-bc7a-4867-af2f-58c5bc77d35f.json
new file mode 100644
index 0000000..86eda33
--- /dev/null
+++ b/src/enm/study-NWKI-3e4eb704-bc7a-4867-af2f-58c5bc77d35f.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-3e4eb704-bc7a-4867-af2f-58c5bc77d35f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ee237892-6184-3016-92af-b41dc14e9f9b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DNH2"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3e6e8d72-8f5a-4d0e-b223-bafe14c1fc5f.json b/src/enm/study-NWKI-3e6e8d72-8f5a-4d0e-b223-bafe14c1fc5f.json
new file mode 100644
index 0000000..97e67a5
--- /dev/null
+++ b/src/enm/study-NWKI-3e6e8d72-8f5a-4d0e-b223-bafe14c1fc5f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-3e6e8d72-8f5a-4d0e-b223-bafe14c1fc5f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-438d1468-d5d7-3977-9dab-15a3a05add38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "BET",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 600
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3ea8081e-a695-4448-b20b-8db60debf249.json b/src/enm/study-NWKI-3ea8081e-a695-4448-b20b-8db60debf249.json
new file mode 100644
index 0000000..28ddcb7
--- /dev/null
+++ b/src/enm/study-NWKI-3ea8081e-a695-4448-b20b-8db60debf249.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-3ea8081e-a695-4448-b20b-8db60debf249",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c7bee4e3-8884-3e29-ad8b-38decf6146fd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "FITC-2DCOOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "FITC"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "FITC"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3efec963-1abc-49bb-b008-5d665f7d2bf6.json b/src/enm/study-NWKI-3efec963-1abc-49bb-b008-5d665f7d2bf6.json
new file mode 100644
index 0000000..a96b4fa
--- /dev/null
+++ b/src/enm/study-NWKI-3efec963-1abc-49bb-b008-5d665f7d2bf6.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-3efec963-1abc-49bb-b008-5d665f7d2bf6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ad1d5068-29cd-3d8c-9ed0-44ed4ce06ddd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 36
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3f4dfa1e-e8c4-43db-b079-7769a06576ee.json b/src/enm/study-NWKI-3f4dfa1e-e8c4-43db-b079-7769a06576ee.json
new file mode 100644
index 0000000..bd4ef7c
--- /dev/null
+++ b/src/enm/study-NWKI-3f4dfa1e-e8c4-43db-b079-7769a06576ee.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-3f4dfa1e-e8c4-43db-b079-7769a06576ee",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ede00e9f-201f-33c9-9191-8dbf67fcf1b1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH-2DAmphPolymer"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "O=CO[H]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "COOH"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3f8b35b3-2871-4ba1-9cac-0bff533fc0ac.json b/src/enm/study-NWKI-3f8b35b3-2871-4ba1-9cac-0bff533fc0ac.json
new file mode 100644
index 0000000..ef4d8d8
--- /dev/null
+++ b/src/enm/study-NWKI-3f8b35b3-2871-4ba1-9cac-0bff533fc0ac.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-3f8b35b3-2871-4ba1-9cac-0bff533fc0ac",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-57943982-0642-388c-be22-f1770d3b620c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-3fc5844e-758a-4723-9853-26c51789b4c5.json b/src/enm/study-NWKI-3fc5844e-758a-4723-9853-26c51789b4c5.json
new file mode 100644
index 0000000..1819c05
--- /dev/null
+++ b/src/enm/study-NWKI-3fc5844e-758a-4723-9853-26c51789b4c5.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-3fc5844e-758a-4723-9853-26c51789b4c5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-86b21444-5403-3e29-b117-e09ef92cca2a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 707
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-40485c29-c870-40f6-a634-682e2601a2d1.json b/src/enm/study-NWKI-40485c29-c870-40f6-a634-682e2601a2d1.json
new file mode 100644
index 0000000..7bbccaa
--- /dev/null
+++ b/src/enm/study-NWKI-40485c29-c870-40f6-a634-682e2601a2d1.json
@@ -0,0 +1,60 @@
+{
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
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+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "r_isUsedforClassification": "false",
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
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+ "loValue": -9.22
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-405149ad-184c-4263-996f-1df90ef019b9.json b/src/enm/study-NWKI-405149ad-184c-4263-996f-1df90ef019b9.json
new file mode 100644
index 0000000..b002bd6
--- /dev/null
+++ b/src/enm/study-NWKI-405149ad-184c-4263-996f-1df90ef019b9.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-405149ad-184c-4263-996f-1df90ef019b9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6e6a5fec-23c2-3fff-8522-a22689091196"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
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+ },
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+ },
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+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
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+ },
+ "result": {
+ "unit": "m^2/g",
+ "loQualifier": ">=",
+ "loValue": 590,
+ "upQualifier": "<=",
+ "upValue": 690
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-407a0c47-e0aa-4f22-812b-f34f49f0fb2f.json b/src/enm/study-NWKI-407a0c47-e0aa-4f22-812b-f34f49f0fb2f.json
new file mode 100644
index 0000000..5a5b5f9
--- /dev/null
+++ b/src/enm/study-NWKI-407a0c47-e0aa-4f22-812b-f34f49f0fb2f.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-407a0c47-e0aa-4f22-812b-f34f49f0fb2f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-845bf8fc-788d-38f2-be58-030f27c0d337"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4171cf30-7412-4059-80ce-8f79a45445b6.json b/src/enm/study-NWKI-4171cf30-7412-4059-80ce-8f79a45445b6.json
new file mode 100644
index 0000000..c4e4e3f
--- /dev/null
+++ b/src/enm/study-NWKI-4171cf30-7412-4059-80ce-8f79a45445b6.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-4171cf30-7412-4059-80ce-8f79a45445b6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-42360b08-f8be-49c6-98e6-bb8616f090b5.json b/src/enm/study-NWKI-42360b08-f8be-49c6-98e6-bb8616f090b5.json
new file mode 100644
index 0000000..a7f7461
--- /dev/null
+++ b/src/enm/study-NWKI-42360b08-f8be-49c6-98e6-bb8616f090b5.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-42360b08-f8be-49c6-98e6-bb8616f090b5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4b4cb369-8202-3483-9220-553e433c9159"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ },
+ "interpretation": {
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+ "effects": [
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+ "endpoint": "ZETA POTENTIAL",
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+ "Remark": null,
+ "pH": null
+ },
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+ "loValue": 3.24
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-424e79ab-f8be-4bad-8c1e-2abf76cdcdd7.json b/src/enm/study-NWKI-424e79ab-f8be-4bad-8c1e-2abf76cdcdd7.json
new file mode 100644
index 0000000..ac92c1c
--- /dev/null
+++ b/src/enm/study-NWKI-424e79ab-f8be-4bad-8c1e-2abf76cdcdd7.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-424e79ab-f8be-4bad-8c1e-2abf76cdcdd7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-743f46ab-ca20-3f60-a14f-1695430eae68"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.envpol.2008.11.004",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 532
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-42778862-5e5d-49a8-98e2-bdc3c9e3ab2a.json b/src/enm/study-NWKI-42778862-5e5d-49a8-98e2-bdc3c9e3ab2a.json
new file mode 100644
index 0000000..508db8d
--- /dev/null
+++ b/src/enm/study-NWKI-42778862-5e5d-49a8-98e2-bdc3c9e3ab2a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-42778862-5e5d-49a8-98e2-bdc3c9e3ab2a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9a0a7a86-fd00-3835-9795-a4da7d9d1544"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 24
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-42951d23-9941-41f1-b599-8adfde19b8aa.json b/src/enm/study-NWKI-42951d23-9941-41f1-b599-8adfde19b8aa.json
new file mode 100644
index 0000000..babe3bb
--- /dev/null
+++ b/src/enm/study-NWKI-42951d23-9941-41f1-b599-8adfde19b8aa.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-42951d23-9941-41f1-b599-8adfde19b8aa",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4b4cb369-8202-3483-9220-553e433c9159"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DCY35"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-42eae623-28f5-4ee5-9698-2669c8328041.json b/src/enm/study-NWKI-42eae623-28f5-4ee5-9698-2669c8328041.json
new file mode 100644
index 0000000..2d4d6a1
--- /dev/null
+++ b/src/enm/study-NWKI-42eae623-28f5-4ee5-9698-2669c8328041.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-42eae623-28f5-4ee5-9698-2669c8328041",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-17c74ed1-b289-3ca1-8477-390a588cb28c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-42eeeb5b-e44c-4039-884d-367249af0038.json b/src/enm/study-NWKI-42eeeb5b-e44c-4039-884d-367249af0038.json
new file mode 100644
index 0000000..92f4a62
--- /dev/null
+++ b/src/enm/study-NWKI-42eeeb5b-e44c-4039-884d-367249af0038.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-42eeeb5b-e44c-4039-884d-367249af0038",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ff480524-2eb0-39e2-a449-47c026f09eb9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 185,
+ "errorValue": 12
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4453c171-34c1-400e-96e5-f213258eb9a0.json b/src/enm/study-NWKI-4453c171-34c1-400e-96e5-f213258eb9a0.json
new file mode 100644
index 0000000..48b572a
--- /dev/null
+++ b/src/enm/study-NWKI-4453c171-34c1-400e-96e5-f213258eb9a0.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-4453c171-34c1-400e-96e5-f213258eb9a0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ca37d03d-af78-3982-8ca0-76025e71fcf1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
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+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-44812f4a-7893-4211-b5d4-d1c61cd9e334.json b/src/enm/study-NWKI-44812f4a-7893-4211-b5d4-d1c61cd9e334.json
new file mode 100644
index 0000000..20d0cbb
--- /dev/null
+++ b/src/enm/study-NWKI-44812f4a-7893-4211-b5d4-d1c61cd9e334.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-44812f4a-7893-4211-b5d4-d1c61cd9e334",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b110d018-6de0-303b-afcc-6a5e1f5911aa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "Shape",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Anatase"
+ },
+ "effects": [
+ {
+ "endpoint": "SHAPE",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Anatase"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-449dbb75-83c8-4f54-8208-3b0f7093ddc5.json b/src/enm/study-NWKI-449dbb75-83c8-4f54-8208-3b0f7093ddc5.json
new file mode 100644
index 0000000..ccdce90
--- /dev/null
+++ b/src/enm/study-NWKI-449dbb75-83c8-4f54-8208-3b0f7093ddc5.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-449dbb75-83c8-4f54-8208-3b0f7093ddc5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fe8fe744-ea1f-3841-9a6d-f81be44651a8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
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+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Ag"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ag"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "TMATCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "TMAT"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SCC[N+](C)(C)C.[I-]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "TMAT"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-45484e90-4453-4b65-a581-2b81994d5d96.json b/src/enm/study-NWKI-45484e90-4453-4b65-a581-2b81994d5d96.json
new file mode 100644
index 0000000..9e47b4e
--- /dev/null
+++ b/src/enm/study-NWKI-45484e90-4453-4b65-a581-2b81994d5d96.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-45484e90-4453-4b65-a581-2b81994d5d96",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-144a9226-4b93-36a9-ba2d-6b6c4903357b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "Serum": {
+ "loValue": "sfMEM"
+ },
+ "pH": {
+ "loValue": 8.12
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-45a2a522-fd42-4b13-a51c-c2ae30d8e4e8.json b/src/enm/study-NWKI-45a2a522-fd42-4b13-a51c-c2ae30d8e4e8.json
new file mode 100644
index 0000000..3ed2d9b
--- /dev/null
+++ b/src/enm/study-NWKI-45a2a522-fd42-4b13-a51c-c2ae30d8e4e8.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-45a2a522-fd42-4b13-a51c-c2ae30d8e4e8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c05becdf-4b9b-3599-9922-89235b2e10da"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 25
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-46021e41-3e84-406a-a9db-36bdaa480006.json b/src/enm/study-NWKI-46021e41-3e84-406a-a9db-36bdaa480006.json
new file mode 100644
index 0000000..63c7454
--- /dev/null
+++ b/src/enm/study-NWKI-46021e41-3e84-406a-a9db-36bdaa480006.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-46021e41-3e84-406a-a9db-36bdaa480006",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ad44f58f-8080-3017-9f8d-485fad044849"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -3.61
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-46590639-f0b8-45ae-ae2f-610b8a912cc4.json b/src/enm/study-NWKI-46590639-f0b8-45ae-ae2f-610b8a912cc4.json
new file mode 100644
index 0000000..512480d
--- /dev/null
+++ b/src/enm/study-NWKI-46590639-f0b8-45ae-ae2f-610b8a912cc4.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-46590639-f0b8-45ae-ae2f-610b8a912cc4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2390517f-b763-3850-b1b4-6e50fee63829"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-46a0c2a5-0e02-4eb7-93fb-e15a56feea9e.json b/src/enm/study-NWKI-46a0c2a5-0e02-4eb7-93fb-e15a56feea9e.json
new file mode 100644
index 0000000..bc8990b
--- /dev/null
+++ b/src/enm/study-NWKI-46a0c2a5-0e02-4eb7-93fb-e15a56feea9e.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-46a0c2a5-0e02-4eb7-93fb-e15a56feea9e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-70e8dac6-42a3-36ed-8fa3-19ffbc3bb69f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "BET",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 50
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4715a11f-9c3a-4a02-b0f4-d5e05baf2e46.json b/src/enm/study-NWKI-4715a11f-9c3a-4a02-b0f4-d5e05baf2e46.json
new file mode 100644
index 0000000..d27c3da
--- /dev/null
+++ b/src/enm/study-NWKI-4715a11f-9c3a-4a02-b0f4-d5e05baf2e46.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-4715a11f-9c3a-4a02-b0f4-d5e05baf2e46",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d0a80e1b-1b7f-35c7-9185-244ccc2c04c2"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 9.7,
+ "errorValue": 0.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4716f798-2c74-459d-90ca-dddaf4d0ef9f.json b/src/enm/study-NWKI-4716f798-2c74-459d-90ca-dddaf4d0ef9f.json
new file mode 100644
index 0000000..cd3a851
--- /dev/null
+++ b/src/enm/study-NWKI-4716f798-2c74-459d-90ca-dddaf4d0ef9f.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-4716f798-2c74-459d-90ca-dddaf4d0ef9f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ad44f58f-8080-3017-9f8d-485fad044849"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DRhodamine-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-474fcad3-d31e-434a-92dc-2c1d94802498.json b/src/enm/study-NWKI-474fcad3-d31e-434a-92dc-2c1d94802498.json
new file mode 100644
index 0000000..844eb5b
--- /dev/null
+++ b/src/enm/study-NWKI-474fcad3-d31e-434a-92dc-2c1d94802498.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-474fcad3-d31e-434a-92dc-2c1d94802498",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-438d1468-d5d7-3977-9dab-15a3a05add38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 100
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-477db1fa-3728-4edb-8502-7c144290d2b9.json b/src/enm/study-NWKI-477db1fa-3728-4edb-8502-7c144290d2b9.json
new file mode 100644
index 0000000..1d85cf9
--- /dev/null
+++ b/src/enm/study-NWKI-477db1fa-3728-4edb-8502-7c144290d2b9.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-477db1fa-3728-4edb-8502-7c144290d2b9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5e5ed57f-33d3-39bb-9511-3604a0babf5e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn2021056",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -34.9
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-480620bc-921d-48cc-9c5b-12b3e6e10cfe.json b/src/enm/study-NWKI-480620bc-921d-48cc-9c5b-12b3e6e10cfe.json
new file mode 100644
index 0000000..fa997e3
--- /dev/null
+++ b/src/enm/study-NWKI-480620bc-921d-48cc-9c5b-12b3e6e10cfe.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-480620bc-921d-48cc-9c5b-12b3e6e10cfe",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4b4cb369-8202-3483-9220-553e433c9159"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DCY35"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cy3.5"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cy3.5"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-485bdc76-7caf-417b-9d38-a4922bbf19fc.json b/src/enm/study-NWKI-485bdc76-7caf-417b-9d38-a4922bbf19fc.json
new file mode 100644
index 0000000..8b6d865
--- /dev/null
+++ b/src/enm/study-NWKI-485bdc76-7caf-417b-9d38-a4922bbf19fc.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-485bdc76-7caf-417b-9d38-a4922bbf19fc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e373781b-461e-35dd-ae27-4169b7d743af"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-494d44b2-073a-4136-b394-0efd79375df2.json b/src/enm/study-NWKI-494d44b2-073a-4136-b394-0efd79375df2.json
new file mode 100644
index 0000000..b0a68cf
--- /dev/null
+++ b/src/enm/study-NWKI-494d44b2-073a-4136-b394-0efd79375df2.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-494d44b2-073a-4136-b394-0efd79375df2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6392b929-1b64-34ce-90c6-162b99ce3992"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 14.7,
+ "errorValue": 5.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-497f175a-9524-4d84-91bc-041d0423e724.json b/src/enm/study-NWKI-497f175a-9524-4d84-91bc-041d0423e724.json
new file mode 100644
index 0000000..b05d0f7
--- /dev/null
+++ b/src/enm/study-NWKI-497f175a-9524-4d84-91bc-041d0423e724.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-497f175a-9524-4d84-91bc-041d0423e724",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-70e8dac6-42a3-36ed-8fa3-19ffbc3bb69f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-49be8b3f-29c1-42d7-ac5f-ab75e8f2f5a2.json b/src/enm/study-NWKI-49be8b3f-29c1-42d7-ac5f-ab75e8f2f5a2.json
new file mode 100644
index 0000000..5758a9f
--- /dev/null
+++ b/src/enm/study-NWKI-49be8b3f-29c1-42d7-ac5f-ab75e8f2f5a2.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-49be8b3f-29c1-42d7-ac5f-ab75e8f2f5a2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8f7f774c-d727-33a9-adc6-9068524faf1c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -11.9
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-49ccb387-6de9-4ff5-b90f-7d40e9d964ca.json b/src/enm/study-NWKI-49ccb387-6de9-4ff5-b90f-7d40e9d964ca.json
new file mode 100644
index 0000000..6308f56
--- /dev/null
+++ b/src/enm/study-NWKI-49ccb387-6de9-4ff5-b90f-7d40e9d964ca.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-49ccb387-6de9-4ff5-b90f-7d40e9d964ca",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3bbccc84-019f-369f-ba70-490fcfde4423"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4a9f81e2-c857-4ca4-820d-95d026a2b83b.json b/src/enm/study-NWKI-4a9f81e2-c857-4ca4-820d-95d026a2b83b.json
new file mode 100644
index 0000000..3204a67
--- /dev/null
+++ b/src/enm/study-NWKI-4a9f81e2-c857-4ca4-820d-95d026a2b83b.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-4a9f81e2-c857-4ca4-820d-95d026a2b83b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-56d49cc3-4a76-354b-9a77-4b2ecb2dbef0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "μg/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 0
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 16
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4ac12800-e71c-437a-b839-fdccb5d18d69.json b/src/enm/study-NWKI-4ac12800-e71c-437a-b839-fdccb5d18d69.json
new file mode 100644
index 0000000..f9bce88
--- /dev/null
+++ b/src/enm/study-NWKI-4ac12800-e71c-437a-b839-fdccb5d18d69.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-4ac12800-e71c-437a-b839-fdccb5d18d69",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-77fb742b-c676-3ad7-bd19-6d5ec1df62ad"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -7.57
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4acc3309-36a7-4ddf-8a38-458856cd36d6.json b/src/enm/study-NWKI-4acc3309-36a7-4ddf-8a38-458856cd36d6.json
new file mode 100644
index 0000000..fd8e51f
--- /dev/null
+++ b/src/enm/study-NWKI-4acc3309-36a7-4ddf-8a38-458856cd36d6.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-4acc3309-36a7-4ddf-8a38-458856cd36d6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 0.75,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4ad357a1-06bf-497a-8ae0-8a39796b6e1b.json b/src/enm/study-NWKI-4ad357a1-06bf-497a-8ae0-8a39796b6e1b.json
new file mode 100644
index 0000000..61cc469
--- /dev/null
+++ b/src/enm/study-NWKI-4ad357a1-06bf-497a-8ae0-8a39796b6e1b.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-4ad357a1-06bf-497a-8ae0-8a39796b6e1b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ae67096a-fca6-3afc-bade-c362e3eeadc8"
+ },
+ "company": {
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+ "name": "NanoWiki"
+ }
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+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
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+ "topcategory": "P-CHEM",
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+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
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+ "Method details": null,
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+ },
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+ }
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+}
diff --git a/src/enm/study-NWKI-4b147634-318e-478b-91fd-be570e516905.json b/src/enm/study-NWKI-4b147634-318e-478b-91fd-be570e516905.json
new file mode 100644
index 0000000..d8a3108
--- /dev/null
+++ b/src/enm/study-NWKI-4b147634-318e-478b-91fd-be570e516905.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-4b147634-318e-478b-91fd-be570e516905",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f40bfb8a-1280-35a2-866c-42b5a3ce13e7"
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+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
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+ "loValue": 2.64
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4b60773a-f65a-438f-8299-286082243561.json b/src/enm/study-NWKI-4b60773a-f65a-438f-8299-286082243561.json
new file mode 100644
index 0000000..fa531b9
--- /dev/null
+++ b/src/enm/study-NWKI-4b60773a-f65a-438f-8299-286082243561.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-4b60773a-f65a-438f-8299-286082243561",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-905e44ef-3f7f-314d-add0-3e00439eaded"
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+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
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+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
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+ "loValue": 3.45
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4b72cf25-f21a-4add-a046-55ffa1030d9a.json b/src/enm/study-NWKI-4b72cf25-f21a-4add-a046-55ffa1030d9a.json
new file mode 100644
index 0000000..9ff1a22
--- /dev/null
+++ b/src/enm/study-NWKI-4b72cf25-f21a-4add-a046-55ffa1030d9a.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-4b72cf25-f21a-4add-a046-55ffa1030d9a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-895a506b-c331-3576-bf9e-cbcde5822c11"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "PBS"
+ }
+ },
+ "result": {
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+}
diff --git a/src/enm/study-NWKI-4b8cbc90-8984-4fa7-8e0d-24205b96917b.json b/src/enm/study-NWKI-4b8cbc90-8984-4fa7-8e0d-24205b96917b.json
new file mode 100644
index 0000000..e2610b4
--- /dev/null
+++ b/src/enm/study-NWKI-4b8cbc90-8984-4fa7-8e0d-24205b96917b.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-4b8cbc90-8984-4fa7-8e0d-24205b96917b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0866f605-4cfb-32a2-a704-2cf2a8d3d9a6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "TESTMAT_FORM": null
+ },
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+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4bb154cc-48e2-4286-bdb0-dd65cfff3bc3.json b/src/enm/study-NWKI-4bb154cc-48e2-4286-bdb0-dd65cfff3bc3.json
new file mode 100644
index 0000000..34fce21
--- /dev/null
+++ b/src/enm/study-NWKI-4bb154cc-48e2-4286-bdb0-dd65cfff3bc3.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-4bb154cc-48e2-4286-bdb0-dd65cfff3bc3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4f1a3729-4a88-31bc-abca-7eb6503a73d4"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
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+ "Type of method": null
+ },
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+ "effects": [
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+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
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+ "result": {
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+ "loValue": 220
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4bd8fefc-f691-4008-a426-c96ca2fda917.json b/src/enm/study-NWKI-4bd8fefc-f691-4008-a426-c96ca2fda917.json
new file mode 100644
index 0000000..9ea9830
--- /dev/null
+++ b/src/enm/study-NWKI-4bd8fefc-f691-4008-a426-c96ca2fda917.json
@@ -0,0 +1,55 @@
+{
+ "uuid": "NWKI-4bd8fefc-f691-4008-a426-c96ca2fda917",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ea48c37d-840a-30d2-9740-1198a7e2c3b6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_MELTING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000256",
+ "title": "4.2 Melting point / freezing point"
+ },
+ "endpoint": "Melting Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ "interpretation": {
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+ "Sublimation": null
+ },
+ "result": {
+ "unit": "Celsius",
+ "loQualifier": ">=",
+ "loValue": 1600
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4bf35dc7-46c6-4803-95b7-96044af583bb.json b/src/enm/study-NWKI-4bf35dc7-46c6-4803-95b7-96044af583bb.json
new file mode 100644
index 0000000..fb484af
--- /dev/null
+++ b/src/enm/study-NWKI-4bf35dc7-46c6-4803-95b7-96044af583bb.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-4bf35dc7-46c6-4803-95b7-96044af583bb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-02981dd4-b7d0-34c8-a0ab-dd19a5a40865"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ }
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+}
diff --git a/src/enm/study-NWKI-4bf8eec4-5811-473c-bb0a-0ef7d57278fc.json b/src/enm/study-NWKI-4bf8eec4-5811-473c-bb0a-0ef7d57278fc.json
new file mode 100644
index 0000000..09dcf0b
--- /dev/null
+++ b/src/enm/study-NWKI-4bf8eec4-5811-473c-bb0a-0ef7d57278fc.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-4bf8eec4-5811-473c-bb0a-0ef7d57278fc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4358aa69-dec1-387a-b7ea-2238198ccdff"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ "effects": [
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+ "endpoint": "ZETA POTENTIAL",
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+ "Serum": {
+ "loValue": "PBS"
+ },
+ "pH": {
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+ }
+ },
+ "result": {
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+ "loValue": -42
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4d004bc3-aed2-42c3-9973-2fbd846c917f.json b/src/enm/study-NWKI-4d004bc3-aed2-42c3-9973-2fbd846c917f.json
new file mode 100644
index 0000000..78311e0
--- /dev/null
+++ b/src/enm/study-NWKI-4d004bc3-aed2-42c3-9973-2fbd846c917f.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-4d004bc3-aed2-42c3-9973-2fbd846c917f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b6c86895-1b73-39ec-8bd2-0106e77a7673"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
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+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DAF488"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "AlexaFluor488"
+ },
+ "ELEMENT_OR_GROUP": {
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+ "TYPE": {
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+ "loValue": "COATING"
+ }
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+ "result": {
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+ "textValue": "AlexaFluor488"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4d3b2e50-6bd6-4ebb-b8d3-ae42c20aa399.json b/src/enm/study-NWKI-4d3b2e50-6bd6-4ebb-b8d3-ae42c20aa399.json
new file mode 100644
index 0000000..38731d0
--- /dev/null
+++ b/src/enm/study-NWKI-4d3b2e50-6bd6-4ebb-b8d3-ae42c20aa399.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-4d3b2e50-6bd6-4ebb-b8d3-ae42c20aa399",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0bb16a46-44a8-353e-ba07-b5835e323537"
+ },
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "interpretation": {
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+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 2900,
+ "errorValue": 1100
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4d9128fa-262f-418c-abc4-358f5d190e64.json b/src/enm/study-NWKI-4d9128fa-262f-418c-abc4-358f5d190e64.json
new file mode 100644
index 0000000..604c5a1
--- /dev/null
+++ b/src/enm/study-NWKI-4d9128fa-262f-418c-abc4-358f5d190e64.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-4d9128fa-262f-418c-abc4-358f5d190e64",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 42
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4ed9f2c7-b2a3-44b9-ac42-cccc38e89ac8.json b/src/enm/study-NWKI-4ed9f2c7-b2a3-44b9-ac42-cccc38e89ac8.json
new file mode 100644
index 0000000..656e8d5
--- /dev/null
+++ b/src/enm/study-NWKI-4ed9f2c7-b2a3-44b9-ac42-cccc38e89ac8.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-4ed9f2c7-b2a3-44b9-ac42-cccc38e89ac8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c35f0f16-4616-3ec6-a142-4d274add68a2"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 43.8,
+ "errorValue": 15.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4f1aee45-76f4-4e13-9498-f3ad8a6c0883.json b/src/enm/study-NWKI-4f1aee45-76f4-4e13-9498-f3ad8a6c0883.json
new file mode 100644
index 0000000..3689e65
--- /dev/null
+++ b/src/enm/study-NWKI-4f1aee45-76f4-4e13-9498-f3ad8a6c0883.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-4f1aee45-76f4-4e13-9498-f3ad8a6c0883",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f4579554-a7fc-3e3f-991a-3b016207fa06"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2011.587903",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-4fac17a1-7915-4937-a74c-180f2ca61e5f.json b/src/enm/study-NWKI-4fac17a1-7915-4937-a74c-180f2ca61e5f.json
new file mode 100644
index 0000000..d505642
--- /dev/null
+++ b/src/enm/study-NWKI-4fac17a1-7915-4937-a74c-180f2ca61e5f.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-4fac17a1-7915-4937-a74c-180f2ca61e5f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4e021275-ae4e-3d24-bdb8-40c6d8d9d6fc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Isoelectric Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ISOELECTRIC POINT",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-50291d37-1850-4345-8632-4f912b91c7c0.json b/src/enm/study-NWKI-50291d37-1850-4345-8632-4f912b91c7c0.json
new file mode 100644
index 0000000..4985cb2
--- /dev/null
+++ b/src/enm/study-NWKI-50291d37-1850-4345-8632-4f912b91c7c0.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-50291d37-1850-4345-8632-4f912b91c7c0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 3.12,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-50af5cfe-a337-4bff-b3a6-9d4048072b16.json b/src/enm/study-NWKI-50af5cfe-a337-4bff-b3a6-9d4048072b16.json
new file mode 100644
index 0000000..922d316
--- /dev/null
+++ b/src/enm/study-NWKI-50af5cfe-a337-4bff-b3a6-9d4048072b16.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-50af5cfe-a337-4bff-b3a6-9d4048072b16",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-67b71fb2-85c1-3130-bd4e-84da8bc05fc9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 10,
+ "upQualifier": "<=",
+ "upValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-50d0445d-2ddf-48f0-97a5-f879b4b71de6.json b/src/enm/study-NWKI-50d0445d-2ddf-48f0-97a5-f879b4b71de6.json
new file mode 100644
index 0000000..9d0d4e5
--- /dev/null
+++ b/src/enm/study-NWKI-50d0445d-2ddf-48f0-97a5-f879b4b71de6.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-50d0445d-2ddf-48f0-97a5-f879b4b71de6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bb304faf-e44e-3103-b2a6-01b99c1c23de"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": -50,
+ "upQualifier": "<=",
+ "upValue": 38
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-50d10201-2928-49a1-82e9-decaf8df67fd.json b/src/enm/study-NWKI-50d10201-2928-49a1-82e9-decaf8df67fd.json
new file mode 100644
index 0000000..f82855e
--- /dev/null
+++ b/src/enm/study-NWKI-50d10201-2928-49a1-82e9-decaf8df67fd.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-50d10201-2928-49a1-82e9-decaf8df67fd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-50db9231-07eb-4856-8521-05b59b840557.json b/src/enm/study-NWKI-50db9231-07eb-4856-8521-05b59b840557.json
new file mode 100644
index 0000000..8868998
--- /dev/null
+++ b/src/enm/study-NWKI-50db9231-07eb-4856-8521-05b59b840557.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-50db9231-07eb-4856-8521-05b59b840557",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 5,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-50e51401-4fb9-4f7b-b958-ebe38f0d9a21.json b/src/enm/study-NWKI-50e51401-4fb9-4f7b-b958-ebe38f0d9a21.json
new file mode 100644
index 0000000..a4b718d
--- /dev/null
+++ b/src/enm/study-NWKI-50e51401-4fb9-4f7b-b958-ebe38f0d9a21.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-50e51401-4fb9-4f7b-b958-ebe38f0d9a21",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b1b44fa-70c1-3034-9c4b-7efb334762e0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 61
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-522b7192-5e42-46b5-91e4-7af1ad67f9f8.json b/src/enm/study-NWKI-522b7192-5e42-46b5-91e4-7af1ad67f9f8.json
new file mode 100644
index 0000000..7fabee9
--- /dev/null
+++ b/src/enm/study-NWKI-522b7192-5e42-46b5-91e4-7af1ad67f9f8.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-522b7192-5e42-46b5-91e4-7af1ad67f9f8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-823e6217-d5b0-3c61-b886-768cfe726d38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 6.3,
+ "errorValue": 0.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-523df19a-2a87-409b-86ae-3e3b39945909.json b/src/enm/study-NWKI-523df19a-2a87-409b-86ae-3e3b39945909.json
new file mode 100644
index 0000000..18f62ec
--- /dev/null
+++ b/src/enm/study-NWKI-523df19a-2a87-409b-86ae-3e3b39945909.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-523df19a-2a87-409b-86ae-3e3b39945909",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cfea3b7c-ee39-34ef-8349-16b1e7825861"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 60
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-524de060-5f0a-498c-9a47-e2bc418e3977.json b/src/enm/study-NWKI-524de060-5f0a-498c-9a47-e2bc418e3977.json
new file mode 100644
index 0000000..34adc8b
--- /dev/null
+++ b/src/enm/study-NWKI-524de060-5f0a-498c-9a47-e2bc418e3977.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-524de060-5f0a-498c-9a47-e2bc418e3977",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0d6f156a-6ce8-3bac-97e3-b5d62ded7f4e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn200546k",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 0.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5295d5ce-3714-411e-b225-0c769a170e59.json b/src/enm/study-NWKI-5295d5ce-3714-411e-b225-0c769a170e59.json
new file mode 100644
index 0000000..a028f47
--- /dev/null
+++ b/src/enm/study-NWKI-5295d5ce-3714-411e-b225-0c769a170e59.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-5295d5ce-3714-411e-b225-0c769a170e59",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b19125a9-4499-3e0e-aa0c-7792401f4900"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DProtamine-2DRhodamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Rhodamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Rhodamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-530d1c38-f820-4849-b3bf-71605163bf76.json b/src/enm/study-NWKI-530d1c38-f820-4849-b3bf-71605163bf76.json
new file mode 100644
index 0000000..31653a7
--- /dev/null
+++ b/src/enm/study-NWKI-530d1c38-f820-4849-b3bf-71605163bf76.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-530d1c38-f820-4849-b3bf-71605163bf76",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-245fc9be-5928-354e-8fd1-ae88663923f1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "Remark": null,
+ "pH": null
+ },
+ "result": {
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+ "loValue": 0.0
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-545da080-c5eb-4a56-b10b-3390d3959238.json b/src/enm/study-NWKI-545da080-c5eb-4a56-b10b-3390d3959238.json
new file mode 100644
index 0000000..3cb850b
--- /dev/null
+++ b/src/enm/study-NWKI-545da080-c5eb-4a56-b10b-3390d3959238.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-545da080-c5eb-4a56-b10b-3390d3959238",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6a8efcf8-a19c-3fb3-b8ca-3f4e1a09fcb0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -50.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-54b3ecd6-68b4-434d-bdaf-32a8c5a6f4f7.json b/src/enm/study-NWKI-54b3ecd6-68b4-434d-bdaf-32a8c5a6f4f7.json
new file mode 100644
index 0000000..b26a23a
--- /dev/null
+++ b/src/enm/study-NWKI-54b3ecd6-68b4-434d-bdaf-32a8c5a6f4f7.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-54b3ecd6-68b4-434d-bdaf-32a8c5a6f4f7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-dfbd99e5-c150-3a5e-9147-59255d42bebb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_value": null
+ },
+ "interpretation": {
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+ "conditions": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 13.1,
+ "errorValue": 5.9
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-55eb46d4-4c78-42d2-9c3a-e131a3a7f19e.json b/src/enm/study-NWKI-55eb46d4-4c78-42d2-9c3a-e131a3a7f19e.json
new file mode 100644
index 0000000..83bf777
--- /dev/null
+++ b/src/enm/study-NWKI-55eb46d4-4c78-42d2-9c3a-e131a3a7f19e.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-55eb46d4-4c78-42d2-9c3a-e131a3a7f19e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-605f4f43-028b-3a42-ae94-9852a9f6f5f8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 331,
+ "errorValue": 19
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-55f1adcf-2ae2-4f2f-b61b-b7fe65cf9650.json b/src/enm/study-NWKI-55f1adcf-2ae2-4f2f-b61b-b7fe65cf9650.json
new file mode 100644
index 0000000..beed3ba
--- /dev/null
+++ b/src/enm/study-NWKI-55f1adcf-2ae2-4f2f-b61b-b7fe65cf9650.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-55f1adcf-2ae2-4f2f-b61b-b7fe65cf9650",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c7bee4e3-8884-3e29-ad8b-38decf6146fd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 36
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-560ae138-7a60-412e-bda8-15ef20c1c0d3.json b/src/enm/study-NWKI-560ae138-7a60-412e-bda8-15ef20c1c0d3.json
new file mode 100644
index 0000000..63bc418
--- /dev/null
+++ b/src/enm/study-NWKI-560ae138-7a60-412e-bda8-15ef20c1c0d3.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-560ae138-7a60-412e-bda8-15ef20c1c0d3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 150,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-566d754e-ac76-4e29-a17e-6e7e815ba719.json b/src/enm/study-NWKI-566d754e-ac76-4e29-a17e-6e7e815ba719.json
new file mode 100644
index 0000000..c9f20ec
--- /dev/null
+++ b/src/enm/study-NWKI-566d754e-ac76-4e29-a17e-6e7e815ba719.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-566d754e-ac76-4e29-a17e-6e7e815ba719",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-696f7b05-2dea-3a14-b080-fef134f4eff5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12,
+ "errorValue": 3.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-56fb25be-18b8-405b-be4f-be843856826b.json b/src/enm/study-NWKI-56fb25be-18b8-405b-be4f-be843856826b.json
new file mode 100644
index 0000000..5eda269
--- /dev/null
+++ b/src/enm/study-NWKI-56fb25be-18b8-405b-be4f-be843856826b.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-56fb25be-18b8-405b-be4f-be843856826b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ed06c39e-c7f2-3173-bd74-35b8257544b5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "r_value": null
+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loQualifier": ">=",
+ "loValue": 129,
+ "upQualifier": "<=",
+ "upValue": 155
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-575b7f67-e068-43e5-b8f4-fae5c192806b.json b/src/enm/study-NWKI-575b7f67-e068-43e5-b8f4-fae5c192806b.json
new file mode 100644
index 0000000..733fc7b
--- /dev/null
+++ b/src/enm/study-NWKI-575b7f67-e068-43e5-b8f4-fae5c192806b.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-575b7f67-e068-43e5-b8f4-fae5c192806b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-369d200e-2bfc-392d-ae00-ceb41fabd459"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
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+ "loValue": "Ag"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ag"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "TMATCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "TMAT"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SCC[N+](C)(C)C.[I-]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
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+ "textValue": "TMAT"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-576e0d8e-08a0-440c-a937-b655c96f1827.json b/src/enm/study-NWKI-576e0d8e-08a0-440c-a937-b655c96f1827.json
new file mode 100644
index 0000000..36fe172
--- /dev/null
+++ b/src/enm/study-NWKI-576e0d8e-08a0-440c-a937-b655c96f1827.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-576e0d8e-08a0-440c-a937-b655c96f1827",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e5b618fd-dd48-3562-9a55-737ac7a68466"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "effects": [
+ {
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+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -10.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-57abdeee-1b76-49b9-a3b3-a0e1e964f2d5.json b/src/enm/study-NWKI-57abdeee-1b76-49b9-a3b3-a0e1e964f2d5.json
new file mode 100644
index 0000000..350d513
--- /dev/null
+++ b/src/enm/study-NWKI-57abdeee-1b76-49b9-a3b3-a0e1e964f2d5.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-57abdeee-1b76-49b9-a3b3-a0e1e964f2d5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 60
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-57c3ba51-9194-4872-ae89-221f6ca96ec2.json b/src/enm/study-NWKI-57c3ba51-9194-4872-ae89-221f6ca96ec2.json
new file mode 100644
index 0000000..409dfe2
--- /dev/null
+++ b/src/enm/study-NWKI-57c3ba51-9194-4872-ae89-221f6ca96ec2.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-57c3ba51-9194-4872-ae89-221f6ca96ec2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-56d49cc3-4a76-354b-9a77-4b2ecb2dbef0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-57d53a2d-4c4e-41db-99aa-e8fcddac22b3.json b/src/enm/study-NWKI-57d53a2d-4c4e-41db-99aa-e8fcddac22b3.json
new file mode 100644
index 0000000..19fe307
--- /dev/null
+++ b/src/enm/study-NWKI-57d53a2d-4c4e-41db-99aa-e8fcddac22b3.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-57d53a2d-4c4e-41db-99aa-e8fcddac22b3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0fef8d9c-b0c4-3e41-88d0-b85cd538a796"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "result": {
+ "unit": null,
+ "loValue": 1.74
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-57e76541-d6b3-46ea-8b97-70dddfd9667b.json b/src/enm/study-NWKI-57e76541-d6b3-46ea-8b97-70dddfd9667b.json
new file mode 100644
index 0000000..4194d7e
--- /dev/null
+++ b/src/enm/study-NWKI-57e76541-d6b3-46ea-8b97-70dddfd9667b.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-57e76541-d6b3-46ea-8b97-70dddfd9667b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3b09fdd1-3024-3be3-b1c6-332b44f75f99"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ },
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+ "loValue": 2.51
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-58446ed4-a39a-4505-b359-f1d3008edf25.json b/src/enm/study-NWKI-58446ed4-a39a-4505-b359-f1d3008edf25.json
new file mode 100644
index 0000000..6cd0f1d
--- /dev/null
+++ b/src/enm/study-NWKI-58446ed4-a39a-4505-b359-f1d3008edf25.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-58446ed4-a39a-4505-b359-f1d3008edf25",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-845bf8fc-788d-38f2-be58-030f27c0d337"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "loValue": 2.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-587bf2ec-a417-4834-8331-2272e3dd6d21.json b/src/enm/study-NWKI-587bf2ec-a417-4834-8331-2272e3dd6d21.json
new file mode 100644
index 0000000..fc30a87
--- /dev/null
+++ b/src/enm/study-NWKI-587bf2ec-a417-4834-8331-2272e3dd6d21.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-587bf2ec-a417-4834-8331-2272e3dd6d21",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-db562080-5286-327a-b813-6775c437385e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DRCOOH"
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+ "DESCRIPTION": {
+ "loQualifier": " ",
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+ "textValue": "RCOOH"
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+}
diff --git a/src/enm/study-NWKI-58c79586-50bf-460d-830d-a14c8ad70f8e.json b/src/enm/study-NWKI-58c79586-50bf-460d-830d-a14c8ad70f8e.json
new file mode 100644
index 0000000..041e774
--- /dev/null
+++ b/src/enm/study-NWKI-58c79586-50bf-460d-830d-a14c8ad70f8e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-58c79586-50bf-460d-830d-a14c8ad70f8e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-916751bb-8457-3844-87c0-ada4c6afd1ab"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "cMEM"
+ }
+ },
+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-58ebc4fe-bf67-4eba-ae0b-02a0964fa04d.json b/src/enm/study-NWKI-58ebc4fe-bf67-4eba-ae0b-02a0964fa04d.json
new file mode 100644
index 0000000..6a33b72
--- /dev/null
+++ b/src/enm/study-NWKI-58ebc4fe-bf67-4eba-ae0b-02a0964fa04d.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-58ebc4fe-bf67-4eba-ae0b-02a0964fa04d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d39efcf3-d871-34c2-ac1c-b48f35bde877"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "r_purposeFlag": null,
+ "r_value": null
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+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 9.48,
+ "errorValue": 1.26
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5939b44d-6d55-4d26-80ff-9f9cd48c58e7.json b/src/enm/study-NWKI-5939b44d-6d55-4d26-80ff-9f9cd48c58e7.json
new file mode 100644
index 0000000..f6abb60
--- /dev/null
+++ b/src/enm/study-NWKI-5939b44d-6d55-4d26-80ff-9f9cd48c58e7.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-5939b44d-6d55-4d26-80ff-9f9cd48c58e7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 50,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-59bb2ce9-3e8b-4b2a-9491-c6e331e716b1.json b/src/enm/study-NWKI-59bb2ce9-3e8b-4b2a-9491-c6e331e716b1.json
new file mode 100644
index 0000000..84dc154
--- /dev/null
+++ b/src/enm/study-NWKI-59bb2ce9-3e8b-4b2a-9491-c6e331e716b1.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-59bb2ce9-3e8b-4b2a-9491-c6e331e716b1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e518c122-5f4f-3611-8b30-56b671883e5c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DED-2DAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Ethylene_Diamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "NCCN"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ethylene_Diamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5a65ec58-f00b-48b5-906b-d3eebf6d34b8.json b/src/enm/study-NWKI-5a65ec58-f00b-48b5-906b-d3eebf6d34b8.json
new file mode 100644
index 0000000..c081ea0
--- /dev/null
+++ b/src/enm/study-NWKI-5a65ec58-f00b-48b5-906b-d3eebf6d34b8.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-5a65ec58-f00b-48b5-906b-d3eebf6d34b8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-37e2b8ec-0e57-3ed8-9afc-93a3030ee25f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 60.6,
+ "errorValue": 15.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5a74bb96-6612-4622-9aa5-e641a09c9a46.json b/src/enm/study-NWKI-5a74bb96-6612-4622-9aa5-e641a09c9a46.json
new file mode 100644
index 0000000..449976a
--- /dev/null
+++ b/src/enm/study-NWKI-5a74bb96-6612-4622-9aa5-e641a09c9a46.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-5a74bb96-6612-4622-9aa5-e641a09c9a46",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8f7f774c-d727-33a9-adc6-9068524faf1c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DCOOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "FITC"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "FITC"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5a843641-8dbf-4bc3-ab49-400d74d27bab.json b/src/enm/study-NWKI-5a843641-8dbf-4bc3-ab49-400d74d27bab.json
new file mode 100644
index 0000000..46abab4
--- /dev/null
+++ b/src/enm/study-NWKI-5a843641-8dbf-4bc3-ab49-400d74d27bab.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-5a843641-8dbf-4bc3-ab49-400d74d27bab",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-04d6ccd0-30ad-3ffc-9f06-8b13709d3a62"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 25
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5acb47b7-d27f-46e6-acfe-6b063106fa87.json b/src/enm/study-NWKI-5acb47b7-d27f-46e6-acfe-6b063106fa87.json
new file mode 100644
index 0000000..12c3e42
--- /dev/null
+++ b/src/enm/study-NWKI-5acb47b7-d27f-46e6-acfe-6b063106fa87.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-5acb47b7-d27f-46e6-acfe-6b063106fa87",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 200,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5bf85889-bc2d-442e-b94f-987670fd6289.json b/src/enm/study-NWKI-5bf85889-bc2d-442e-b94f-987670fd6289.json
new file mode 100644
index 0000000..51ca0af
--- /dev/null
+++ b/src/enm/study-NWKI-5bf85889-bc2d-442e-b94f-987670fd6289.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-5bf85889-bc2d-442e-b94f-987670fd6289",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-155bb96c-2d7e-384d-b55d-45856eeda386"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5cb2dd63-eaab-411b-97ee-e3f3bae24663.json b/src/enm/study-NWKI-5cb2dd63-eaab-411b-97ee-e3f3bae24663.json
new file mode 100644
index 0000000..d3e0d09
--- /dev/null
+++ b/src/enm/study-NWKI-5cb2dd63-eaab-411b-97ee-e3f3bae24663.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-5cb2dd63-eaab-411b-97ee-e3f3bae24663",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-694f4202-c0ba-3ed9-a0f3-0a5ccba9e9c1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 226
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5cc3a4e9-7c58-44cf-8e6f-5f297ff4ca6e.json b/src/enm/study-NWKI-5cc3a4e9-7c58-44cf-8e6f-5f297ff4ca6e.json
new file mode 100644
index 0000000..20cd9b2
--- /dev/null
+++ b/src/enm/study-NWKI-5cc3a4e9-7c58-44cf-8e6f-5f297ff4ca6e.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-5cc3a4e9-7c58-44cf-8e6f-5f297ff4ca6e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e373781b-461e-35dd-ae27-4169b7d743af"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5d7782f7-9f36-4183-a45f-f3e1ff12f8dd.json b/src/enm/study-NWKI-5d7782f7-9f36-4183-a45f-f3e1ff12f8dd.json
new file mode 100644
index 0000000..e306744
--- /dev/null
+++ b/src/enm/study-NWKI-5d7782f7-9f36-4183-a45f-f3e1ff12f8dd.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-5d7782f7-9f36-4183-a45f-f3e1ff12f8dd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-605f4f43-028b-3a42-ae94-9852a9f6f5f8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 291,
+ "errorValue": 9
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5da37282-461c-4564-bfde-d111e4f79e1e.json b/src/enm/study-NWKI-5da37282-461c-4564-bfde-d111e4f79e1e.json
new file mode 100644
index 0000000..7fc5f64
--- /dev/null
+++ b/src/enm/study-NWKI-5da37282-461c-4564-bfde-d111e4f79e1e.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-5da37282-461c-4564-bfde-d111e4f79e1e",
+ "owner": {
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+ "uuid": "NWKI-758c06ae-dc1f-3cbe-a409-91d14e5113d1"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
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+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
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+ "loValue": -6.54
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5e7ff0d3-fbef-44a0-bbdb-bb0c03fff028.json b/src/enm/study-NWKI-5e7ff0d3-fbef-44a0-bbdb-bb0c03fff028.json
new file mode 100644
index 0000000..a370173
--- /dev/null
+++ b/src/enm/study-NWKI-5e7ff0d3-fbef-44a0-bbdb-bb0c03fff028.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-5e7ff0d3-fbef-44a0-bbdb-bb0c03fff028",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-dd6b8324-524e-3281-8bf4-09044fbf01ab"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 40,
+ "upQualifier": "<=",
+ "upValue": 70
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5f0da6d9-855e-49d6-a566-f8485a4d71f7.json b/src/enm/study-NWKI-5f0da6d9-855e-49d6-a566-f8485a4d71f7.json
new file mode 100644
index 0000000..76a9f1e
--- /dev/null
+++ b/src/enm/study-NWKI-5f0da6d9-855e-49d6-a566-f8485a4d71f7.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-5f0da6d9-855e-49d6-a566-f8485a4d71f7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3e42f6e5-635a-3f1e-a51a-39ce26751ec9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.82
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5f0f3ffb-4032-48eb-acec-e47064fd0318.json b/src/enm/study-NWKI-5f0f3ffb-4032-48eb-acec-e47064fd0318.json
new file mode 100644
index 0000000..74acf1a
--- /dev/null
+++ b/src/enm/study-NWKI-5f0f3ffb-4032-48eb-acec-e47064fd0318.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-5f0f3ffb-4032-48eb-acec-e47064fd0318",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cad5bf58-cc90-33e5-88bb-bad4c9f9fe9e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.34
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5f396653-ef15-4c28-b5fb-5b0a89ff145e.json b/src/enm/study-NWKI-5f396653-ef15-4c28-b5fb-5b0a89ff145e.json
new file mode 100644
index 0000000..72e71f8
--- /dev/null
+++ b/src/enm/study-NWKI-5f396653-ef15-4c28-b5fb-5b0a89ff145e.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-5f396653-ef15-4c28-b5fb-5b0a89ff145e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6d5462cc-7e11-3919-b769-135f56fd2536"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.soilbio.2013.01.016",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loQualifier": ">=",
+ "loValue": 8,
+ "upQualifier": "<=",
+ "upValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-5fc1235f-99c4-411a-9173-17421cc226c4.json b/src/enm/study-NWKI-5fc1235f-99c4-411a-9173-17421cc226c4.json
new file mode 100644
index 0000000..29d8c64
--- /dev/null
+++ b/src/enm/study-NWKI-5fc1235f-99c4-411a-9173-17421cc226c4.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-5fc1235f-99c4-411a-9173-17421cc226c4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e866549e-38cf-3b98-a0b1-a483e275d261"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 1,
+ "upQualifier": "<=",
+ "upValue": 39
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6013fae6-bdb8-4b76-b5e1-1e50b224f6ad.json b/src/enm/study-NWKI-6013fae6-bdb8-4b76-b5e1-1e50b224f6ad.json
new file mode 100644
index 0000000..4e9a6ff
--- /dev/null
+++ b/src/enm/study-NWKI-6013fae6-bdb8-4b76-b5e1-1e50b224f6ad.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-6013fae6-bdb8-4b76-b5e1-1e50b224f6ad",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a95db64e-5499-371a-bdce-a4aa31f93218"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Ag"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ag"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MEECoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MEE"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SCCOCCO"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "MEE"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-60bad0b9-135c-4b51-b477-8873d6b53e62.json b/src/enm/study-NWKI-60bad0b9-135c-4b51-b477-8873d6b53e62.json
new file mode 100644
index 0000000..9357f2f
--- /dev/null
+++ b/src/enm/study-NWKI-60bad0b9-135c-4b51-b477-8873d6b53e62.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-60bad0b9-135c-4b51-b477-8873d6b53e62",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ede0d5b5-191a-3003-ac70-a97397ea7bb2"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 101,
+ "errorValue": 7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-60c801de-4063-4e94-badd-5b3ea137ee2e.json b/src/enm/study-NWKI-60c801de-4063-4e94-badd-5b3ea137ee2e.json
new file mode 100644
index 0000000..f6d09aa
--- /dev/null
+++ b/src/enm/study-NWKI-60c801de-4063-4e94-badd-5b3ea137ee2e.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-60c801de-4063-4e94-badd-5b3ea137ee2e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-60c8a08a-5a5d-4e78-9eca-c17fa70ada6e.json b/src/enm/study-NWKI-60c8a08a-5a5d-4e78-9eca-c17fa70ada6e.json
new file mode 100644
index 0000000..07eabd7
--- /dev/null
+++ b/src/enm/study-NWKI-60c8a08a-5a5d-4e78-9eca-c17fa70ada6e.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-60c8a08a-5a5d-4e78-9eca-c17fa70ada6e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0a6e319e-71fc-37f7-b88d-fbda2e07ccc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-60d8ff8a-334d-4aec-8840-fe9237f2ed52.json b/src/enm/study-NWKI-60d8ff8a-334d-4aec-8840-fe9237f2ed52.json
new file mode 100644
index 0000000..9505a84
--- /dev/null
+++ b/src/enm/study-NWKI-60d8ff8a-334d-4aec-8840-fe9237f2ed52.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-60d8ff8a-334d-4aec-8840-fe9237f2ed52",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-61140943-e725-4000-adda-54d56323cc38.json b/src/enm/study-NWKI-61140943-e725-4000-adda-54d56323cc38.json
new file mode 100644
index 0000000..aa0ae3f
--- /dev/null
+++ b/src/enm/study-NWKI-61140943-e725-4000-adda-54d56323cc38.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-61140943-e725-4000-adda-54d56323cc38",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c012600e-ca8e-31db-a7a8-d9f6a74e2464"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-61169e69-160a-4883-bb5b-57864cfaa226.json b/src/enm/study-NWKI-61169e69-160a-4883-bb5b-57864cfaa226.json
new file mode 100644
index 0000000..a5a0792
--- /dev/null
+++ b/src/enm/study-NWKI-61169e69-160a-4883-bb5b-57864cfaa226.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-61169e69-160a-4883-bb5b-57864cfaa226",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c5e226b0-d405-32d5-a652-7f7f1f0eb55d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 81,
+ "errorValue": 12
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-615e9046-2352-43b1-8061-c5863c389eba.json b/src/enm/study-NWKI-615e9046-2352-43b1-8061-c5863c389eba.json
new file mode 100644
index 0000000..ca400ed
--- /dev/null
+++ b/src/enm/study-NWKI-615e9046-2352-43b1-8061-c5863c389eba.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-615e9046-2352-43b1-8061-c5863c389eba",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-619ad025-d12a-40d6-b802-11c7bc1c5f0c.json b/src/enm/study-NWKI-619ad025-d12a-40d6-b802-11c7bc1c5f0c.json
new file mode 100644
index 0000000..c2c8296
--- /dev/null
+++ b/src/enm/study-NWKI-619ad025-d12a-40d6-b802-11c7bc1c5f0c.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-619ad025-d12a-40d6-b802-11c7bc1c5f0c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ab2d4bdd-7a72-3e26-8552-5bb6027896bb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -12.2,
+ "errorValue": 0.97
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-61ac7714-8bcb-4b22-9c49-8897a34459f8.json b/src/enm/study-NWKI-61ac7714-8bcb-4b22-9c49-8897a34459f8.json
new file mode 100644
index 0000000..5315605
--- /dev/null
+++ b/src/enm/study-NWKI-61ac7714-8bcb-4b22-9c49-8897a34459f8.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-61ac7714-8bcb-4b22-9c49-8897a34459f8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-afc33b0f-f6ce-3c1b-8a3d-cede13515323"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Amino_SPARK680"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Amino_SPARK680"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-61cd966e-d293-4e74-810d-c96d7226a885.json b/src/enm/study-NWKI-61cd966e-d293-4e74-810d-c96d7226a885.json
new file mode 100644
index 0000000..1517664
--- /dev/null
+++ b/src/enm/study-NWKI-61cd966e-d293-4e74-810d-c96d7226a885.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-61cd966e-d293-4e74-810d-c96d7226a885",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-61e74c49-caba-449a-ab8b-79ce619474c7.json b/src/enm/study-NWKI-61e74c49-caba-449a-ab8b-79ce619474c7.json
new file mode 100644
index 0000000..c4a2e6e
--- /dev/null
+++ b/src/enm/study-NWKI-61e74c49-caba-449a-ab8b-79ce619474c7.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-61e74c49-caba-449a-ab8b-79ce619474c7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8c5b9350-2c03-3173-9615-cabfbe6929c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 100
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-623ab83d-a129-4153-b30d-a653ecea4137.json b/src/enm/study-NWKI-623ab83d-a129-4153-b30d-a653ecea4137.json
new file mode 100644
index 0000000..e3c5c4b
--- /dev/null
+++ b/src/enm/study-NWKI-623ab83d-a129-4153-b30d-a653ecea4137.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-623ab83d-a129-4153-b30d-a653ecea4137",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-62723dfc-941e-4efa-971d-d4061c205c37.json b/src/enm/study-NWKI-62723dfc-941e-4efa-971d-d4061c205c37.json
new file mode 100644
index 0000000..4c37a92
--- /dev/null
+++ b/src/enm/study-NWKI-62723dfc-941e-4efa-971d-d4061c205c37.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-62723dfc-941e-4efa-971d-d4061c205c37",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-56d49cc3-4a76-354b-9a77-4b2ecb2dbef0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "BET",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 70
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-62c6c671-de0c-421a-9359-a4fb45ba7d0a.json b/src/enm/study-NWKI-62c6c671-de0c-421a-9359-a4fb45ba7d0a.json
new file mode 100644
index 0000000..340a55d
--- /dev/null
+++ b/src/enm/study-NWKI-62c6c671-de0c-421a-9359-a4fb45ba7d0a.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-62c6c671-de0c-421a-9359-a4fb45ba7d0a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-77fb742b-c676-3ad7-bd19-6d5ec1df62ad"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DED-2DVT680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Ethylene_Diamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "NCCN"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ethylene_Diamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-632864fb-ead5-48bd-abdf-93ac2d6db3d2.json b/src/enm/study-NWKI-632864fb-ead5-48bd-abdf-93ac2d6db3d2.json
new file mode 100644
index 0000000..f2322a1
--- /dev/null
+++ b/src/enm/study-NWKI-632864fb-ead5-48bd-abdf-93ac2d6db3d2.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-632864fb-ead5-48bd-abdf-93ac2d6db3d2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6340f201-e40f-44e0-9cc0-bd91711785b2.json b/src/enm/study-NWKI-6340f201-e40f-44e0-9cc0-bd91711785b2.json
new file mode 100644
index 0000000..c090b11
--- /dev/null
+++ b/src/enm/study-NWKI-6340f201-e40f-44e0-9cc0-bd91711785b2.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-6340f201-e40f-44e0-9cc0-bd91711785b2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-473ed1d8-ae5a-3c80-b3f7-50dbc4fd9a3b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -21,
+ "errorValue": 5.16
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-637e25c9-223d-4680-b358-bf11344c0385.json b/src/enm/study-NWKI-637e25c9-223d-4680-b358-bf11344c0385.json
new file mode 100644
index 0000000..e9674c1
--- /dev/null
+++ b/src/enm/study-NWKI-637e25c9-223d-4680-b358-bf11344c0385.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-637e25c9-223d-4680-b358-bf11344c0385",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6cab56b4-69d9-36e0-8c17-f467d08b2555"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -12.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-63d64d8b-df0b-4dae-84e6-ae6bd3ac623c.json b/src/enm/study-NWKI-63d64d8b-df0b-4dae-84e6-ae6bd3ac623c.json
new file mode 100644
index 0000000..3888c56
--- /dev/null
+++ b/src/enm/study-NWKI-63d64d8b-df0b-4dae-84e6-ae6bd3ac623c.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-63d64d8b-df0b-4dae-84e6-ae6bd3ac623c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7efe542f-264c-3b57-a516-410b730df963"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 28
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-63de74e0-3b63-435a-ad62-cc9645d3cc15.json b/src/enm/study-NWKI-63de74e0-3b63-435a-ad62-cc9645d3cc15.json
new file mode 100644
index 0000000..f6737c3
--- /dev/null
+++ b/src/enm/study-NWKI-63de74e0-3b63-435a-ad62-cc9645d3cc15.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-63de74e0-3b63-435a-ad62-cc9645d3cc15",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-438d1468-d5d7-3977-9dab-15a3a05add38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 120
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-63df02d3-d55b-4a25-abfd-f73d2b958075.json b/src/enm/study-NWKI-63df02d3-d55b-4a25-abfd-f73d2b958075.json
new file mode 100644
index 0000000..280bd5f
--- /dev/null
+++ b/src/enm/study-NWKI-63df02d3-d55b-4a25-abfd-f73d2b958075.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-63df02d3-d55b-4a25-abfd-f73d2b958075",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-11bd7878-7fd9-365c-8f01-a452d9c7f4ec"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 14
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-640f103a-1955-416a-a656-356884730cea.json b/src/enm/study-NWKI-640f103a-1955-416a-a656-356884730cea.json
new file mode 100644
index 0000000..69cc83e
--- /dev/null
+++ b/src/enm/study-NWKI-640f103a-1955-416a-a656-356884730cea.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-640f103a-1955-416a-a656-356884730cea",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f3be029d-68f6-310a-87a4-ceffee1b4eda"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 8,
+ "upQualifier": "<=",
+ "upValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-64af3435-8edb-4585-8167-3a4e8ed2ea6a.json b/src/enm/study-NWKI-64af3435-8edb-4585-8167-3a4e8ed2ea6a.json
new file mode 100644
index 0000000..9262279
--- /dev/null
+++ b/src/enm/study-NWKI-64af3435-8edb-4585-8167-3a4e8ed2ea6a.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-64af3435-8edb-4585-8167-3a4e8ed2ea6a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d0a80e1b-1b7f-35c7-9185-244ccc2c04c2"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 88,
+ "errorValue": 12
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-64c482f1-7978-4160-8430-08ab8392c4a2.json b/src/enm/study-NWKI-64c482f1-7978-4160-8430-08ab8392c4a2.json
new file mode 100644
index 0000000..0d57126
--- /dev/null
+++ b/src/enm/study-NWKI-64c482f1-7978-4160-8430-08ab8392c4a2.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-64c482f1-7978-4160-8430-08ab8392c4a2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6e6a5fec-23c2-3fff-8522-a22689091196"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 5,
+ "upQualifier": "<=",
+ "upValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-64f89bf1-d825-4cdb-8c59-87301ec7befc.json b/src/enm/study-NWKI-64f89bf1-d825-4cdb-8c59-87301ec7befc.json
new file mode 100644
index 0000000..732e6ba
--- /dev/null
+++ b/src/enm/study-NWKI-64f89bf1-d825-4cdb-8c59-87301ec7befc.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-64f89bf1-d825-4cdb-8c59-87301ec7befc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-916751bb-8457-3844-87c0-ada4c6afd1ab"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "PBS"
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 76
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-65922873-2b18-467a-8b0d-7d985d296419.json b/src/enm/study-NWKI-65922873-2b18-467a-8b0d-7d985d296419.json
new file mode 100644
index 0000000..723c9f4
--- /dev/null
+++ b/src/enm/study-NWKI-65922873-2b18-467a-8b0d-7d985d296419.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-65922873-2b18-467a-8b0d-7d985d296419",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a95db64e-5499-371a-bdce-a4aa31f93218"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn200546k",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 0.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-65e45fc5-68ff-416e-b735-6e10a7eae383.json b/src/enm/study-NWKI-65e45fc5-68ff-416e-b735-6e10a7eae383.json
new file mode 100644
index 0000000..eb9d677
--- /dev/null
+++ b/src/enm/study-NWKI-65e45fc5-68ff-416e-b735-6e10a7eae383.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-65e45fc5-68ff-416e-b735-6e10a7eae383",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a4b3e23-3327-3421-b20a-2e71939b44b1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -20.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-65f7ef57-354f-4d82-ac39-a4e4aafb49b0.json b/src/enm/study-NWKI-65f7ef57-354f-4d82-ac39-a4e4aafb49b0.json
new file mode 100644
index 0000000..2787772
--- /dev/null
+++ b/src/enm/study-NWKI-65f7ef57-354f-4d82-ac39-a4e4aafb49b0.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-65f7ef57-354f-4d82-ac39-a4e4aafb49b0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-66eb1f6f-5461-4ab5-a476-38de7568df69.json b/src/enm/study-NWKI-66eb1f6f-5461-4ab5-a476-38de7568df69.json
new file mode 100644
index 0000000..6207cdc
--- /dev/null
+++ b/src/enm/study-NWKI-66eb1f6f-5461-4ab5-a476-38de7568df69.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-66eb1f6f-5461-4ab5-a476-38de7568df69",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bb97285c-a58f-34c0-aa16-d5eac02280fa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 4.98,
+ "errorValue": 0.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-66eeb62c-4a93-4a73-bb8a-276e5552057b.json b/src/enm/study-NWKI-66eeb62c-4a93-4a73-bb8a-276e5552057b.json
new file mode 100644
index 0000000..ea9bd4f
--- /dev/null
+++ b/src/enm/study-NWKI-66eeb62c-4a93-4a73-bb8a-276e5552057b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-66eeb62c-4a93-4a73-bb8a-276e5552057b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-671aae68-2d9e-4cda-b5d5-136d0abcb830.json b/src/enm/study-NWKI-671aae68-2d9e-4cda-b5d5-136d0abcb830.json
new file mode 100644
index 0000000..16233ae
--- /dev/null
+++ b/src/enm/study-NWKI-671aae68-2d9e-4cda-b5d5-136d0abcb830.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-671aae68-2d9e-4cda-b5d5-136d0abcb830",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d63286d0-3205-3216-92ce-e9e2632aca9e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6784e795-4fb3-45e8-8fca-faeb49758250.json b/src/enm/study-NWKI-6784e795-4fb3-45e8-8fca-faeb49758250.json
new file mode 100644
index 0000000..2ad4983
--- /dev/null
+++ b/src/enm/study-NWKI-6784e795-4fb3-45e8-8fca-faeb49758250.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-6784e795-4fb3-45e8-8fca-faeb49758250",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-395bf212-b710-3385-9c23-715a7055b015"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-682685bb-7a15-4b40-abf0-1f94320c83c4.json b/src/enm/study-NWKI-682685bb-7a15-4b40-abf0-1f94320c83c4.json
new file mode 100644
index 0000000..41af496
--- /dev/null
+++ b/src/enm/study-NWKI-682685bb-7a15-4b40-abf0-1f94320c83c4.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-682685bb-7a15-4b40-abf0-1f94320c83c4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8f43d9fb-94ae-3d2b-8bb6-e8eb060e3b1b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Isoelectric Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ISOELECTRIC POINT",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 8.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-683a3a11-0be9-4fbe-a659-ce59d3de9778.json b/src/enm/study-NWKI-683a3a11-0be9-4fbe-a659-ce59d3de9778.json
new file mode 100644
index 0000000..e4dfb3b
--- /dev/null
+++ b/src/enm/study-NWKI-683a3a11-0be9-4fbe-a659-ce59d3de9778.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-683a3a11-0be9-4fbe-a659-ce59d3de9778",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0866f605-4cfb-32a2-a704-2cf2a8d3d9a6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 3.45
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-68518793-a783-4d93-94ce-118ae5876f5f.json b/src/enm/study-NWKI-68518793-a783-4d93-94ce-118ae5876f5f.json
new file mode 100644
index 0000000..168188c
--- /dev/null
+++ b/src/enm/study-NWKI-68518793-a783-4d93-94ce-118ae5876f5f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-68518793-a783-4d93-94ce-118ae5876f5f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8667bfb7-a5da-3eb0-b9d7-86e2c8f06f19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 19.2,
+ "errorValue": 4.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6882b12d-f37a-4512-b33a-0cf922f61e1f.json b/src/enm/study-NWKI-6882b12d-f37a-4512-b33a-0cf922f61e1f.json
new file mode 100644
index 0000000..cbc5411
--- /dev/null
+++ b/src/enm/study-NWKI-6882b12d-f37a-4512-b33a-0cf922f61e1f.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-6882b12d-f37a-4512-b33a-0cf922f61e1f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b1b44fa-70c1-3034-9c4b-7efb334762e0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "Shape",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Rutile-Anatase"
+ },
+ "effects": [
+ {
+ "endpoint": "SHAPE",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Rutile-Anatase"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-691d614d-a497-4a8f-bfdc-a6375b2e5230.json b/src/enm/study-NWKI-691d614d-a497-4a8f-bfdc-a6375b2e5230.json
new file mode 100644
index 0000000..49ecd4e
--- /dev/null
+++ b/src/enm/study-NWKI-691d614d-a497-4a8f-bfdc-a6375b2e5230.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-691d614d-a497-4a8f-bfdc-a6375b2e5230",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9a13f473-8a29-32e4-9653-ec03f5fb8923"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_value": null
+ },
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+ },
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+ {
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
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+ "loValue": "CdSe"
+ },
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+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "CdSe"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "AmphPolymer-2DPEG"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Amphiphillic_Polymer"
+ },
+ "ELEMENT_OR_GROUP": {
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+ },
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+ "TYPE": {
+ "loQualifier": " ",
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+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Amphiphillic_Polymer"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-692e09d2-5c50-48ac-99ae-5f29d6d76c6b.json b/src/enm/study-NWKI-692e09d2-5c50-48ac-99ae-5f29d6d76c6b.json
new file mode 100644
index 0000000..c9bd197
--- /dev/null
+++ b/src/enm/study-NWKI-692e09d2-5c50-48ac-99ae-5f29d6d76c6b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-692e09d2-5c50-48ac-99ae-5f29d6d76c6b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6967b484-7d24-4415-b944-ba5a978a90e5.json b/src/enm/study-NWKI-6967b484-7d24-4415-b944-ba5a978a90e5.json
new file mode 100644
index 0000000..895bfb0
--- /dev/null
+++ b/src/enm/study-NWKI-6967b484-7d24-4415-b944-ba5a978a90e5.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-6967b484-7d24-4415-b944-ba5a978a90e5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-506de59a-ae92-361b-a934-0fdfa41101c0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DVT680-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Protamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Protamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-697e44f6-d1ab-4c2d-a376-b27b73527cde.json b/src/enm/study-NWKI-697e44f6-d1ab-4c2d-a376-b27b73527cde.json
new file mode 100644
index 0000000..aa42ed3
--- /dev/null
+++ b/src/enm/study-NWKI-697e44f6-d1ab-4c2d-a376-b27b73527cde.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-697e44f6-d1ab-4c2d-a376-b27b73527cde",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4551e0f7-e515-3cdb-a099-c2b99b04883d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 3.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-69eced5c-94d1-4166-b97f-16df82011345.json b/src/enm/study-NWKI-69eced5c-94d1-4166-b97f-16df82011345.json
new file mode 100644
index 0000000..9b5b4be
--- /dev/null
+++ b/src/enm/study-NWKI-69eced5c-94d1-4166-b97f-16df82011345.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-69eced5c-94d1-4166-b97f-16df82011345",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a32cb420-7aa2-3130-9612-edfe833d83fc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 50,
+ "upQualifier": "<=",
+ "upValue": 70
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6a508e43-b24e-4c97-b503-62c22c4f73ce.json b/src/enm/study-NWKI-6a508e43-b24e-4c97-b503-62c22c4f73ce.json
new file mode 100644
index 0000000..34fdff1
--- /dev/null
+++ b/src/enm/study-NWKI-6a508e43-b24e-4c97-b503-62c22c4f73ce.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-6a508e43-b24e-4c97-b503-62c22c4f73ce",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bec49753-e5ff-3f5d-96a4-69a07da2de45"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
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+ },
+ "result": {
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+ "loValue": 22.5,
+ "errorValue": 6.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6ab0a013-da8f-44be-938b-9371e5d3204a.json b/src/enm/study-NWKI-6ab0a013-da8f-44be-938b-9371e5d3204a.json
new file mode 100644
index 0000000..d7039c6
--- /dev/null
+++ b/src/enm/study-NWKI-6ab0a013-da8f-44be-938b-9371e5d3204a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-6ab0a013-da8f-44be-938b-9371e5d3204a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-04887adf-9687-3699-8054-e7e3f695e6db"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6abcbd39-35c8-49c6-87b5-df816062ff1e.json b/src/enm/study-NWKI-6abcbd39-35c8-49c6-87b5-df816062ff1e.json
new file mode 100644
index 0000000..ca02305
--- /dev/null
+++ b/src/enm/study-NWKI-6abcbd39-35c8-49c6-87b5-df816062ff1e.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-6abcbd39-35c8-49c6-87b5-df816062ff1e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ad1d5068-29cd-3d8c-9ed0-44ed4ce06ddd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DVT680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "VT680"
+ },
+ "ELEMENT_OR_GROUP": {
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+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "VT680"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6ac5caa9-3bac-4c7b-82a5-a2a8dbd9662e.json b/src/enm/study-NWKI-6ac5caa9-3bac-4c7b-82a5-a2a8dbd9662e.json
new file mode 100644
index 0000000..ac6050e
--- /dev/null
+++ b/src/enm/study-NWKI-6ac5caa9-3bac-4c7b-82a5-a2a8dbd9662e.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-6ac5caa9-3bac-4c7b-82a5-a2a8dbd9662e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4beee533-65e4-364a-adb7-7a520180de61"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 140
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6b99a175-d74d-4b75-8d95-6c5cdfd44b77.json b/src/enm/study-NWKI-6b99a175-d74d-4b75-8d95-6c5cdfd44b77.json
new file mode 100644
index 0000000..22b904d
--- /dev/null
+++ b/src/enm/study-NWKI-6b99a175-d74d-4b75-8d95-6c5cdfd44b77.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-6b99a175-d74d-4b75-8d95-6c5cdfd44b77",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 150,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6baece3d-5a42-491e-8a52-1e6dcb6f9c16.json b/src/enm/study-NWKI-6baece3d-5a42-491e-8a52-1e6dcb6f9c16.json
new file mode 100644
index 0000000..00cde1f
--- /dev/null
+++ b/src/enm/study-NWKI-6baece3d-5a42-491e-8a52-1e6dcb6f9c16.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-6baece3d-5a42-491e-8a52-1e6dcb6f9c16",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8196e92b-c46d-3c14-9410-e87992810710"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "ED-2DPVA"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Ethylene_Diamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "NCCN"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ethylene_Diamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6bbb3609-fac2-40f4-b5bd-5fe1a1752123.json b/src/enm/study-NWKI-6bbb3609-fac2-40f4-b5bd-5fe1a1752123.json
new file mode 100644
index 0000000..2d34645
--- /dev/null
+++ b/src/enm/study-NWKI-6bbb3609-fac2-40f4-b5bd-5fe1a1752123.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-6bbb3609-fac2-40f4-b5bd-5fe1a1752123",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-438d1468-d5d7-3977-9dab-15a3a05add38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 135
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6bf0a7f3-3346-488b-b1e9-1955be794790.json b/src/enm/study-NWKI-6bf0a7f3-3346-488b-b1e9-1955be794790.json
new file mode 100644
index 0000000..cc085c8
--- /dev/null
+++ b/src/enm/study-NWKI-6bf0a7f3-3346-488b-b1e9-1955be794790.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-6bf0a7f3-3346-488b-b1e9-1955be794790",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ec00c05f-0b35-3c5a-b16f-7a3560213764"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFTIC-2DSI"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "FITC"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "FITC"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6bf2f56b-24a9-4340-b7f5-8e45fe446d9c.json b/src/enm/study-NWKI-6bf2f56b-24a9-4340-b7f5-8e45fe446d9c.json
new file mode 100644
index 0000000..ab7c3e7
--- /dev/null
+++ b/src/enm/study-NWKI-6bf2f56b-24a9-4340-b7f5-8e45fe446d9c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-6bf2f56b-24a9-4340-b7f5-8e45fe446d9c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5f88a526-3e3f-3da5-8082-8d1da0cdfefa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 13
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6bfc3b55-c53c-4b28-a094-351b9097689a.json b/src/enm/study-NWKI-6bfc3b55-c53c-4b28-a094-351b9097689a.json
new file mode 100644
index 0000000..2aff23b
--- /dev/null
+++ b/src/enm/study-NWKI-6bfc3b55-c53c-4b28-a094-351b9097689a.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-6bfc3b55-c53c-4b28-a094-351b9097689a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-71060af4-1613-35cf-95ee-2a039be0388a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 76,
+ "errorValue": 10.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6c5523aa-3814-41a9-8ecf-f3d9e1fe54a1.json b/src/enm/study-NWKI-6c5523aa-3814-41a9-8ecf-f3d9e1fe54a1.json
new file mode 100644
index 0000000..729d8c5
--- /dev/null
+++ b/src/enm/study-NWKI-6c5523aa-3814-41a9-8ecf-f3d9e1fe54a1.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-6c5523aa-3814-41a9-8ecf-f3d9e1fe54a1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e078849d-6137-33fc-b103-d458cb77184a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 110,
+ "errorValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6d2a9c66-a782-4fce-be33-3570612ae7f9.json b/src/enm/study-NWKI-6d2a9c66-a782-4fce-be33-3570612ae7f9.json
new file mode 100644
index 0000000..793975d
--- /dev/null
+++ b/src/enm/study-NWKI-6d2a9c66-a782-4fce-be33-3570612ae7f9.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-6d2a9c66-a782-4fce-be33-3570612ae7f9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b19125a9-4499-3e0e-aa0c-7792401f4900"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DProtamine-2DRhodamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6da0d960-35d3-4b23-a173-f72214be91c9.json b/src/enm/study-NWKI-6da0d960-35d3-4b23-a173-f72214be91c9.json
new file mode 100644
index 0000000..e838dcb
--- /dev/null
+++ b/src/enm/study-NWKI-6da0d960-35d3-4b23-a173-f72214be91c9.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-6da0d960-35d3-4b23-a173-f72214be91c9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-002f5129-d46a-39c7-8f26-5626aec2174e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2011.587903",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 68
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6e00aa34-24b7-4414-ab3f-01dac388cfd3.json b/src/enm/study-NWKI-6e00aa34-24b7-4414-ab3f-01dac388cfd3.json
new file mode 100644
index 0000000..e0aa8de
--- /dev/null
+++ b/src/enm/study-NWKI-6e00aa34-24b7-4414-ab3f-01dac388cfd3.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-6e00aa34-24b7-4414-ab3f-01dac388cfd3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0455b6e1-5203-37bb-a98b-20460acceda1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DCY35-2DTat"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cy3.5"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cy3.5"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-6e4da6a5-c3cc-4d15-9f28-d4462792e8fa.json b/src/enm/study-NWKI-6e4da6a5-c3cc-4d15-9f28-d4462792e8fa.json
new file mode 100644
index 0000000..d11aa2d
--- /dev/null
+++ b/src/enm/study-NWKI-6e4da6a5-c3cc-4d15-9f28-d4462792e8fa.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-6e4da6a5-c3cc-4d15-9f28-d4462792e8fa",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b4d33a5-b573-3dbe-9ec3-9d2a9bc42a2e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 3.37,
+ "errorValue": 0.57
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-70113708-d18b-4539-93ab-b866d5a05700.json b/src/enm/study-NWKI-70113708-d18b-4539-93ab-b866d5a05700.json
new file mode 100644
index 0000000..4e4bcd1
--- /dev/null
+++ b/src/enm/study-NWKI-70113708-d18b-4539-93ab-b866d5a05700.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-70113708-d18b-4539-93ab-b866d5a05700",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-895a506b-c331-3576-bf9e-cbcde5822c11"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "Serum": {
+ "loValue": "sfMEM"
+ },
+ "pH": {
+ "loValue": 7.98
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -21
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7047ec54-4363-4217-b0bf-9b8dc6816321.json b/src/enm/study-NWKI-7047ec54-4363-4217-b0bf-9b8dc6816321.json
new file mode 100644
index 0000000..9c77ffc
--- /dev/null
+++ b/src/enm/study-NWKI-7047ec54-4363-4217-b0bf-9b8dc6816321.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-7047ec54-4363-4217-b0bf-9b8dc6816321",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d63286d0-3205-3216-92ce-e9e2632aca9e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG-2DAminoSPARK680IVM"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PEG"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PEG"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-70e8b5b5-4372-4ab2-a285-a8b623b5286e.json b/src/enm/study-NWKI-70e8b5b5-4372-4ab2-a285-a8b623b5286e.json
new file mode 100644
index 0000000..9521100
--- /dev/null
+++ b/src/enm/study-NWKI-70e8b5b5-4372-4ab2-a285-a8b623b5286e.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-70e8b5b5-4372-4ab2-a285-a8b623b5286e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c2ab6def-8305-3b78-958a-4657b3363e11"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -33
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-71efc69b-47a4-46f9-95cf-094d9b61ea83.json b/src/enm/study-NWKI-71efc69b-47a4-46f9-95cf-094d9b61ea83.json
new file mode 100644
index 0000000..7ab5119
--- /dev/null
+++ b/src/enm/study-NWKI-71efc69b-47a4-46f9-95cf-094d9b61ea83.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-71efc69b-47a4-46f9-95cf-094d9b61ea83",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-438d1468-d5d7-3977-9dab-15a3a05add38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 0
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7238a946-65a9-4767-9857-e655fb3766af.json b/src/enm/study-NWKI-7238a946-65a9-4767-9857-e655fb3766af.json
new file mode 100644
index 0000000..bc010c9
--- /dev/null
+++ b/src/enm/study-NWKI-7238a946-65a9-4767-9857-e655fb3766af.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-7238a946-65a9-4767-9857-e655fb3766af",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 200,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-72aa6911-b06c-4440-96d5-9209a49aceb3.json b/src/enm/study-NWKI-72aa6911-b06c-4440-96d5-9209a49aceb3.json
new file mode 100644
index 0000000..96ff553
--- /dev/null
+++ b/src/enm/study-NWKI-72aa6911-b06c-4440-96d5-9209a49aceb3.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-72aa6911-b06c-4440-96d5-9209a49aceb3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ec00c05f-0b35-3c5a-b16f-7a3560213764"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFTIC-2DSI"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-72d5df53-e275-429b-b016-acd988de6623.json b/src/enm/study-NWKI-72d5df53-e275-429b-b016-acd988de6623.json
new file mode 100644
index 0000000..8a04e8c
--- /dev/null
+++ b/src/enm/study-NWKI-72d5df53-e275-429b-b016-acd988de6623.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-72d5df53-e275-429b-b016-acd988de6623",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-86b21444-5403-3e29-b117-e09ef92cca2a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-72e8aef4-1362-43e6-a9db-e5762369bdd5.json b/src/enm/study-NWKI-72e8aef4-1362-43e6-a9db-e5762369bdd5.json
new file mode 100644
index 0000000..0372545
--- /dev/null
+++ b/src/enm/study-NWKI-72e8aef4-1362-43e6-a9db-e5762369bdd5.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-72e8aef4-1362-43e6-a9db-e5762369bdd5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-734860bb-ab9d-468a-97a0-699ad0a6b5a6.json b/src/enm/study-NWKI-734860bb-ab9d-468a-97a0-699ad0a6b5a6.json
new file mode 100644
index 0000000..4ec8734
--- /dev/null
+++ b/src/enm/study-NWKI-734860bb-ab9d-468a-97a0-699ad0a6b5a6.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-734860bb-ab9d-468a-97a0-699ad0a6b5a6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3d8aaa66-97d9-351b-9771-691300d5e97c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 42,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-738ed836-1ded-475f-9c03-e0ab21241fa2.json b/src/enm/study-NWKI-738ed836-1ded-475f-9c03-e0ab21241fa2.json
new file mode 100644
index 0000000..ebf499d
--- /dev/null
+++ b/src/enm/study-NWKI-738ed836-1ded-475f-9c03-e0ab21241fa2.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-738ed836-1ded-475f-9c03-e0ab21241fa2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9a13f473-8a29-32e4-9653-ec03f5fb8923"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -11.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-73c27928-2a28-43a0-a6d6-239372d0ce63.json b/src/enm/study-NWKI-73c27928-2a28-43a0-a6d6-239372d0ce63.json
new file mode 100644
index 0000000..027dfed
--- /dev/null
+++ b/src/enm/study-NWKI-73c27928-2a28-43a0-a6d6-239372d0ce63.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-73c27928-2a28-43a0-a6d6-239372d0ce63",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-db562080-5286-327a-b813-6775c437385e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 38
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-73e01519-c024-4897-b01d-ce4498bf39f5.json b/src/enm/study-NWKI-73e01519-c024-4897-b01d-ce4498bf39f5.json
new file mode 100644
index 0000000..c6fca45
--- /dev/null
+++ b/src/enm/study-NWKI-73e01519-c024-4897-b01d-ce4498bf39f5.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-73e01519-c024-4897-b01d-ce4498bf39f5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8c5b9350-2c03-3173-9615-cabfbe6929c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 70
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-747ef516-d7f4-4088-ae9b-cd7f03254766.json b/src/enm/study-NWKI-747ef516-d7f4-4088-ae9b-cd7f03254766.json
new file mode 100644
index 0000000..f64d0d4
--- /dev/null
+++ b/src/enm/study-NWKI-747ef516-d7f4-4088-ae9b-cd7f03254766.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-747ef516-d7f4-4088-ae9b-cd7f03254766",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-566286ef-03eb-317a-8d9d-24fffefefc0b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn200546k",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 1.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-749775b3-4a3a-4e7e-9fee-422114dc700d.json b/src/enm/study-NWKI-749775b3-4a3a-4e7e-9fee-422114dc700d.json
new file mode 100644
index 0000000..fc61cc9
--- /dev/null
+++ b/src/enm/study-NWKI-749775b3-4a3a-4e7e-9fee-422114dc700d.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-749775b3-4a3a-4e7e-9fee-422114dc700d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-438d1468-d5d7-3977-9dab-15a3a05add38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-752659af-c93e-48c9-a3ba-84063d1c76d0.json b/src/enm/study-NWKI-752659af-c93e-48c9-a3ba-84063d1c76d0.json
new file mode 100644
index 0000000..2d7aa68
--- /dev/null
+++ b/src/enm/study-NWKI-752659af-c93e-48c9-a3ba-84063d1c76d0.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-752659af-c93e-48c9-a3ba-84063d1c76d0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-535c1a8b-71d0-3388-aaf5-e3a5c86510cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -59.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7558ca2a-c4f0-4c5c-b6b2-e6eabf75bad5.json b/src/enm/study-NWKI-7558ca2a-c4f0-4c5c-b6b2-e6eabf75bad5.json
new file mode 100644
index 0000000..66686da
--- /dev/null
+++ b/src/enm/study-NWKI-7558ca2a-c4f0-4c5c-b6b2-e6eabf75bad5.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-7558ca2a-c4f0-4c5c-b6b2-e6eabf75bad5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7580b78e-f6ab-4615-89e2-ec3487c23316.json b/src/enm/study-NWKI-7580b78e-f6ab-4615-89e2-ec3487c23316.json
new file mode 100644
index 0000000..1f8ab65
--- /dev/null
+++ b/src/enm/study-NWKI-7580b78e-f6ab-4615-89e2-ec3487c23316.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-7580b78e-f6ab-4615-89e2-ec3487c23316",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cfea3b7c-ee39-34ef-8349-16b1e7825861"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DRhodamine-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Protamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Protamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-75c8848d-c75a-4628-a3e6-ebdac796acf9.json b/src/enm/study-NWKI-75c8848d-c75a-4628-a3e6-ebdac796acf9.json
new file mode 100644
index 0000000..27d1153
--- /dev/null
+++ b/src/enm/study-NWKI-75c8848d-c75a-4628-a3e6-ebdac796acf9.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-75c8848d-c75a-4628-a3e6-ebdac796acf9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-566286ef-03eb-317a-8d9d-24fffefefc0b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Ag"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ag"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MESCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MES"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SCCS(=O)(=O)[O-].[Na+]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "MES"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-75da2ea6-d0d3-4a13-8e26-43f82a437d8a.json b/src/enm/study-NWKI-75da2ea6-d0d3-4a13-8e26-43f82a437d8a.json
new file mode 100644
index 0000000..63a0b1d
--- /dev/null
+++ b/src/enm/study-NWKI-75da2ea6-d0d3-4a13-8e26-43f82a437d8a.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-75da2ea6-d0d3-4a13-8e26-43f82a437d8a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bb2f1a47-0260-3271-b9c3-edb850d15be9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1039/C4FD00117F",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "Å",
+ "loQualifier": ">=",
+ "loValue": 25,
+ "upQualifier": "<=",
+ "upValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7663a389-7d00-4dca-84ce-ae8134f5c34d.json b/src/enm/study-NWKI-7663a389-7d00-4dca-84ce-ae8134f5c34d.json
new file mode 100644
index 0000000..0141053
--- /dev/null
+++ b/src/enm/study-NWKI-7663a389-7d00-4dca-84ce-ae8134f5c34d.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-7663a389-7d00-4dca-84ce-ae8134f5c34d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-768421ee-d5b3-4964-9f46-fb1cbf0afc2f.json b/src/enm/study-NWKI-768421ee-d5b3-4964-9f46-fb1cbf0afc2f.json
new file mode 100644
index 0000000..36f5389
--- /dev/null
+++ b/src/enm/study-NWKI-768421ee-d5b3-4964-9f46-fb1cbf0afc2f.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-768421ee-d5b3-4964-9f46-fb1cbf0afc2f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-144a9226-4b93-36a9-ba2d-6b6c4903357b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "PBS"
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 158
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-76deec17-0c64-4888-83cd-468ed71b340d.json b/src/enm/study-NWKI-76deec17-0c64-4888-83cd-468ed71b340d.json
new file mode 100644
index 0000000..b106fb7
--- /dev/null
+++ b/src/enm/study-NWKI-76deec17-0c64-4888-83cd-468ed71b340d.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-76deec17-0c64-4888-83cd-468ed71b340d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4e62b022-02b9-35e7-a653-7ee317f54ae8"
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+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3390/ijerph110908867",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 14,
+ "errorValue": 4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-76fa4f88-0375-441b-ab01-f1c1a1003c83.json b/src/enm/study-NWKI-76fa4f88-0375-441b-ab01-f1c1a1003c83.json
new file mode 100644
index 0000000..b048383
--- /dev/null
+++ b/src/enm/study-NWKI-76fa4f88-0375-441b-ab01-f1c1a1003c83.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-76fa4f88-0375-441b-ab01-f1c1a1003c83",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0e10a982-4c8b-3f90-af19-8cd443575fc4"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 40,
+ "upQualifier": "<=",
+ "upValue": 70
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-77206c3d-0288-45eb-9c5c-6f5e5245e499.json b/src/enm/study-NWKI-77206c3d-0288-45eb-9c5c-6f5e5245e499.json
new file mode 100644
index 0000000..828c348
--- /dev/null
+++ b/src/enm/study-NWKI-77206c3d-0288-45eb-9c5c-6f5e5245e499.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-77206c3d-0288-45eb-9c5c-6f5e5245e499",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6ede15ea-8037-379f-933e-7b947e155c6a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1039/C4FD00117F",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "Å",
+ "loQualifier": ">=",
+ "loValue": 25,
+ "upQualifier": "<=",
+ "upValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7768d3c9-59f0-40c7-8c3f-0391d02d48cb.json b/src/enm/study-NWKI-7768d3c9-59f0-40c7-8c3f-0391d02d48cb.json
new file mode 100644
index 0000000..f5bf837
--- /dev/null
+++ b/src/enm/study-NWKI-7768d3c9-59f0-40c7-8c3f-0391d02d48cb.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-7768d3c9-59f0-40c7-8c3f-0391d02d48cb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a03a76c5-85b2-3b10-b567-87ca006c15ac"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 11.8,
+ "errorValue": 3.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-778c56be-5ec6-4032-90fe-f5d965330f71.json b/src/enm/study-NWKI-778c56be-5ec6-4032-90fe-f5d965330f71.json
new file mode 100644
index 0000000..47c08b4
--- /dev/null
+++ b/src/enm/study-NWKI-778c56be-5ec6-4032-90fe-f5d965330f71.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-778c56be-5ec6-4032-90fe-f5d965330f71",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 100
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-77a0bdb0-e565-46c3-aacd-f5a21ca277ba.json b/src/enm/study-NWKI-77a0bdb0-e565-46c3-aacd-f5a21ca277ba.json
new file mode 100644
index 0000000..5bb788e
--- /dev/null
+++ b/src/enm/study-NWKI-77a0bdb0-e565-46c3-aacd-f5a21ca277ba.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-77a0bdb0-e565-46c3-aacd-f5a21ca277ba",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-11ae9232-1521-31d6-9466-c902c43d94fe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DTatPeptide"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Tat_Peptide"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Tat_Peptide"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7805dbcb-b630-4900-85b4-f481b61a6700.json b/src/enm/study-NWKI-7805dbcb-b630-4900-85b4-f481b61a6700.json
new file mode 100644
index 0000000..76562f9
--- /dev/null
+++ b/src/enm/study-NWKI-7805dbcb-b630-4900-85b4-f481b61a6700.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-7805dbcb-b630-4900-85b4-f481b61a6700",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-239abeb4-eb11-3e6e-8301-d486e21861aa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -54.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-788732bb-6b81-4d0b-a592-ddcf1c28215c.json b/src/enm/study-NWKI-788732bb-6b81-4d0b-a592-ddcf1c28215c.json
new file mode 100644
index 0000000..6cb4a0b
--- /dev/null
+++ b/src/enm/study-NWKI-788732bb-6b81-4d0b-a592-ddcf1c28215c.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-788732bb-6b81-4d0b-a592-ddcf1c28215c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7680f6c2-68d8-3ee4-b84b-8107da3f6e19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "DextranCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-79239c97-8c61-42a5-b567-49225a4c097d.json b/src/enm/study-NWKI-79239c97-8c61-42a5-b567-49225a4c097d.json
new file mode 100644
index 0000000..fde9a7f
--- /dev/null
+++ b/src/enm/study-NWKI-79239c97-8c61-42a5-b567-49225a4c097d.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-79239c97-8c61-42a5-b567-49225a4c097d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52e8adb0-6aba-3e7f-bc0c-85cb36c394a2"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "BET",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loQualifier": ">=",
+ "loValue": 300
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-79a0ef0d-c979-4cb3-b2fd-548525f90784.json b/src/enm/study-NWKI-79a0ef0d-c979-4cb3-b2fd-548525f90784.json
new file mode 100644
index 0000000..5040e55
--- /dev/null
+++ b/src/enm/study-NWKI-79a0ef0d-c979-4cb3-b2fd-548525f90784.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-79a0ef0d-c979-4cb3-b2fd-548525f90784",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8c5b9350-2c03-3173-9615-cabfbe6929c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 35
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-79cd1b2b-5087-4093-a1bf-a35101e22425.json b/src/enm/study-NWKI-79cd1b2b-5087-4093-a1bf-a35101e22425.json
new file mode 100644
index 0000000..25b91b2
--- /dev/null
+++ b/src/enm/study-NWKI-79cd1b2b-5087-4093-a1bf-a35101e22425.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-79cd1b2b-5087-4093-a1bf-a35101e22425",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7a9b2e95-0470-4a91-b2e3-f1190082b8ef.json b/src/enm/study-NWKI-7a9b2e95-0470-4a91-b2e3-f1190082b8ef.json
new file mode 100644
index 0000000..25db6c1
--- /dev/null
+++ b/src/enm/study-NWKI-7a9b2e95-0470-4a91-b2e3-f1190082b8ef.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-7a9b2e95-0470-4a91-b2e3-f1190082b8ef",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-85b50517-fdea-3aa6-abbd-dd506393aaa5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 8,
+ "upQualifier": "<=",
+ "upValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7ab06dee-e576-4808-8c00-6a3085733458.json b/src/enm/study-NWKI-7ab06dee-e576-4808-8c00-6a3085733458.json
new file mode 100644
index 0000000..7ac516e
--- /dev/null
+++ b/src/enm/study-NWKI-7ab06dee-e576-4808-8c00-6a3085733458.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-7ab06dee-e576-4808-8c00-6a3085733458",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-205a198f-fcb8-3870-b99c-c6f252783613"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.envpol.2008.11.004",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 60
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7ad548f9-6e7a-42f8-9093-c57657cc0152.json b/src/enm/study-NWKI-7ad548f9-6e7a-42f8-9093-c57657cc0152.json
new file mode 100644
index 0000000..15df3ff
--- /dev/null
+++ b/src/enm/study-NWKI-7ad548f9-6e7a-42f8-9093-c57657cc0152.json
@@ -0,0 +1,54 @@
+{
+ "uuid": "NWKI-7ad548f9-6e7a-42f8-9093-c57657cc0152",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-67b71fb2-85c1-3130-bd4e-84da8bc05fc9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_BOILING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000257",
+ "title": "4.3 Boiling point"
+ },
+ "endpoint": "Boiling Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Boiling point",
+ "conditions": {
+ "Atm. Pressure": null,
+ "Decomposition": null
+ },
+ "result": {
+ "unit": "°C",
+ "loValue": 2230
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7af108f2-05bc-4a05-8c0e-1c25e1df902e.json b/src/enm/study-NWKI-7af108f2-05bc-4a05-8c0e-1c25e1df902e.json
new file mode 100644
index 0000000..f81f785
--- /dev/null
+++ b/src/enm/study-NWKI-7af108f2-05bc-4a05-8c0e-1c25e1df902e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-7af108f2-05bc-4a05-8c0e-1c25e1df902e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-994226ce-df01-3717-b45d-376f645a8d47"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7c7cc761-6167-4f01-bc70-1e227d40ee50.json b/src/enm/study-NWKI-7c7cc761-6167-4f01-bc70-1e227d40ee50.json
new file mode 100644
index 0000000..f73dfd1
--- /dev/null
+++ b/src/enm/study-NWKI-7c7cc761-6167-4f01-bc70-1e227d40ee50.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-7c7cc761-6167-4f01-bc70-1e227d40ee50",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 31.4,
+ "errorValue": 3.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7cc65f18-bc91-4048-b73c-5de3962794a2.json b/src/enm/study-NWKI-7cc65f18-bc91-4048-b73c-5de3962794a2.json
new file mode 100644
index 0000000..08fa8d3
--- /dev/null
+++ b/src/enm/study-NWKI-7cc65f18-bc91-4048-b73c-5de3962794a2.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-7cc65f18-bc91-4048-b73c-5de3962794a2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3e6392b9-35fb-39ad-ad98-f6d6de37659a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -52.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7d1bd000-b1da-4f1e-b1f3-0dc4cfb7c580.json b/src/enm/study-NWKI-7d1bd000-b1da-4f1e-b1f3-0dc4cfb7c580.json
new file mode 100644
index 0000000..3638ad7
--- /dev/null
+++ b/src/enm/study-NWKI-7d1bd000-b1da-4f1e-b1f3-0dc4cfb7c580.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-7d1bd000-b1da-4f1e-b1f3-0dc4cfb7c580",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d8f70c6c-3496-3ad3-8ab3-e4f08a178d30"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 66,
+ "errorValue": 5.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7d6af12a-493d-43f2-89c0-0f4bcdf01aa2.json b/src/enm/study-NWKI-7d6af12a-493d-43f2-89c0-0f4bcdf01aa2.json
new file mode 100644
index 0000000..861a4c4
--- /dev/null
+++ b/src/enm/study-NWKI-7d6af12a-493d-43f2-89c0-0f4bcdf01aa2.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-7d6af12a-493d-43f2-89c0-0f4bcdf01aa2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7fca9f1b-fb2a-3fa5-a080-21391413787d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Ag"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ag"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MEEECoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MEEE"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SCCOCCOCCO"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "MEEE"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7d72e67e-e739-4b03-bd83-a64ee99ea87b.json b/src/enm/study-NWKI-7d72e67e-e739-4b03-bd83-a64ee99ea87b.json
new file mode 100644
index 0000000..448bf80
--- /dev/null
+++ b/src/enm/study-NWKI-7d72e67e-e739-4b03-bd83-a64ee99ea87b.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-7d72e67e-e739-4b03-bd83-a64ee99ea87b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fc00f3ef-464d-32d3-9d12-7e78d25db6ce"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 4.98,
+ "errorValue": 0.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7daf91aa-55cd-4134-823f-507d470782dd.json b/src/enm/study-NWKI-7daf91aa-55cd-4134-823f-507d470782dd.json
new file mode 100644
index 0000000..ea9641e
--- /dev/null
+++ b/src/enm/study-NWKI-7daf91aa-55cd-4134-823f-507d470782dd.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-7daf91aa-55cd-4134-823f-507d470782dd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-674cfd7c-bc77-36c7-bbe0-d52dd0233d64"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "Shape",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Primarily gamma phase"
+ },
+ "effects": [
+ {
+ "endpoint": "SHAPE",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Primarily gamma phase"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7dcedd15-3194-4b36-980e-ccf0d9f9cd64.json b/src/enm/study-NWKI-7dcedd15-3194-4b36-980e-ccf0d9f9cd64.json
new file mode 100644
index 0000000..3e0dce6
--- /dev/null
+++ b/src/enm/study-NWKI-7dcedd15-3194-4b36-980e-ccf0d9f9cd64.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-7dcedd15-3194-4b36-980e-ccf0d9f9cd64",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93a9eb3-83df-3522-b417-7b3a379054a6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Average Length",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Average Length",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "μm",
+ "loValue": 1.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7e127b23-d54f-4fb6-aecf-3a3d2c3ca482.json b/src/enm/study-NWKI-7e127b23-d54f-4fb6-aecf-3a3d2c3ca482.json
new file mode 100644
index 0000000..5b6ffbd
--- /dev/null
+++ b/src/enm/study-NWKI-7e127b23-d54f-4fb6-aecf-3a3d2c3ca482.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-7e127b23-d54f-4fb6-aecf-3a3d2c3ca482",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8667bfb7-a5da-3eb0-b9d7-86e2c8f06f19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -58
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7e264886-37ae-4a67-aeb4-f7050badc42f.json b/src/enm/study-NWKI-7e264886-37ae-4a67-aeb4-f7050badc42f.json
new file mode 100644
index 0000000..693fbc7
--- /dev/null
+++ b/src/enm/study-NWKI-7e264886-37ae-4a67-aeb4-f7050badc42f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-7e264886-37ae-4a67-aeb4-f7050badc42f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 3000,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 35
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7e2e36fe-303f-4576-a1e8-ffcee6b3ee4a.json b/src/enm/study-NWKI-7e2e36fe-303f-4576-a1e8-ffcee6b3ee4a.json
new file mode 100644
index 0000000..f18f112
--- /dev/null
+++ b/src/enm/study-NWKI-7e2e36fe-303f-4576-a1e8-ffcee6b3ee4a.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-7e2e36fe-303f-4576-a1e8-ffcee6b3ee4a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3481f716-18fa-39b3-aa54-4acb67877194"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -9.08
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7f5e6119-a6a6-42ee-8b17-260f67461566.json b/src/enm/study-NWKI-7f5e6119-a6a6-42ee-8b17-260f67461566.json
new file mode 100644
index 0000000..899270b
--- /dev/null
+++ b/src/enm/study-NWKI-7f5e6119-a6a6-42ee-8b17-260f67461566.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-7f5e6119-a6a6-42ee-8b17-260f67461566",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-47d254de-8242-3374-9ed3-085227d473cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG-2DED-2DAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7f8d8e04-e3c9-4ea4-9df4-7b57920649f6.json b/src/enm/study-NWKI-7f8d8e04-e3c9-4ea4-9df4-7b57920649f6.json
new file mode 100644
index 0000000..862014e
--- /dev/null
+++ b/src/enm/study-NWKI-7f8d8e04-e3c9-4ea4-9df4-7b57920649f6.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-7f8d8e04-e3c9-4ea4-9df4-7b57920649f6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3bbccc84-019f-369f-ba70-490fcfde4423"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.01
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7f9c80a3-8113-4697-9c9f-6501b9101571.json b/src/enm/study-NWKI-7f9c80a3-8113-4697-9c9f-6501b9101571.json
new file mode 100644
index 0000000..dc0536b
--- /dev/null
+++ b/src/enm/study-NWKI-7f9c80a3-8113-4697-9c9f-6501b9101571.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-7f9c80a3-8113-4697-9c9f-6501b9101571",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8f43d9fb-94ae-3d2b-8bb6-e8eb060e3b1b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 120
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7fd4ed19-440a-4c19-9563-9e54b040dee8.json b/src/enm/study-NWKI-7fd4ed19-440a-4c19-9563-9e54b040dee8.json
new file mode 100644
index 0000000..46d7ddf
--- /dev/null
+++ b/src/enm/study-NWKI-7fd4ed19-440a-4c19-9563-9e54b040dee8.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-7fd4ed19-440a-4c19-9563-9e54b040dee8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-7fe22f1d-e036-445c-8c61-46ab914871c6.json b/src/enm/study-NWKI-7fe22f1d-e036-445c-8c61-46ab914871c6.json
new file mode 100644
index 0000000..8813fd0
--- /dev/null
+++ b/src/enm/study-NWKI-7fe22f1d-e036-445c-8c61-46ab914871c6.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-7fe22f1d-e036-445c-8c61-46ab914871c6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 8
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 100
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-81088c1d-747c-46a8-b3e7-5559d15ead7c.json b/src/enm/study-NWKI-81088c1d-747c-46a8-b3e7-5559d15ead7c.json
new file mode 100644
index 0000000..d069467
--- /dev/null
+++ b/src/enm/study-NWKI-81088c1d-747c-46a8-b3e7-5559d15ead7c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-81088c1d-747c-46a8-b3e7-5559d15ead7c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8c5b9350-2c03-3173-9615-cabfbe6929c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-81217635-d689-47e3-ac04-edd53506bff8.json b/src/enm/study-NWKI-81217635-d689-47e3-ac04-edd53506bff8.json
new file mode 100644
index 0000000..aac5298
--- /dev/null
+++ b/src/enm/study-NWKI-81217635-d689-47e3-ac04-edd53506bff8.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-81217635-d689-47e3-ac04-edd53506bff8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4e62b022-02b9-35e7-a653-7ee317f54ae8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3390/ijerph110908867",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 9,
+ "errorValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-81278690-b827-4d5b-8c54-092a3c1c354a.json b/src/enm/study-NWKI-81278690-b827-4d5b-8c54-092a3c1c354a.json
new file mode 100644
index 0000000..71a5b7d
--- /dev/null
+++ b/src/enm/study-NWKI-81278690-b827-4d5b-8c54-092a3c1c354a.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-81278690-b827-4d5b-8c54-092a3c1c354a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-81546ced-dc22-4cb5-8737-19aa4ad1de93.json b/src/enm/study-NWKI-81546ced-dc22-4cb5-8737-19aa4ad1de93.json
new file mode 100644
index 0000000..e5f4e5e
--- /dev/null
+++ b/src/enm/study-NWKI-81546ced-dc22-4cb5-8737-19aa4ad1de93.json
@@ -0,0 +1,54 @@
+{
+ "uuid": "NWKI-81546ced-dc22-4cb5-8737-19aa4ad1de93",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6e6a5fec-23c2-3fff-8522-a22689091196"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_BOILING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000257",
+ "title": "4.3 Boiling point"
+ },
+ "endpoint": "Boiling Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ },
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+ "effects": [
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+ "endpoint": "Boiling point",
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+ "Atm. Pressure": null,
+ "Decomposition": null
+ },
+ "result": {
+ "unit": "°C",
+ "loValue": 2230
+ }
+ }
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+}
diff --git a/src/enm/study-NWKI-81fdf4e1-b6a9-4129-9d10-7c001906557a.json b/src/enm/study-NWKI-81fdf4e1-b6a9-4129-9d10-7c001906557a.json
new file mode 100644
index 0000000..b08cbd0
--- /dev/null
+++ b/src/enm/study-NWKI-81fdf4e1-b6a9-4129-9d10-7c001906557a.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-81fdf4e1-b6a9-4129-9d10-7c001906557a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-05ce8604-4efc-376b-a88f-338a90465243"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2015.1017022",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Average Length",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ },
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "μm",
+ "loValue": 5.7,
+ "errorValue": 3.7
+ }
+ }
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+}
diff --git a/src/enm/study-NWKI-825f394c-e93a-4520-a6b4-cd40458ab3a7.json b/src/enm/study-NWKI-825f394c-e93a-4520-a6b4-cd40458ab3a7.json
new file mode 100644
index 0000000..354760b
--- /dev/null
+++ b/src/enm/study-NWKI-825f394c-e93a-4520-a6b4-cd40458ab3a7.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-825f394c-e93a-4520-a6b4-cd40458ab3a7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "effects": [
+ {
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+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
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+ "loValue": 95
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+ }
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+}
diff --git a/src/enm/study-NWKI-826c8eb7-0eac-4b4f-bfc3-085855091704.json b/src/enm/study-NWKI-826c8eb7-0eac-4b4f-bfc3-085855091704.json
new file mode 100644
index 0000000..6154b5d
--- /dev/null
+++ b/src/enm/study-NWKI-826c8eb7-0eac-4b4f-bfc3-085855091704.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-826c8eb7-0eac-4b4f-bfc3-085855091704",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-758c06ae-dc1f-3cbe-a409-91d14e5113d1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
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+}
diff --git a/src/enm/study-NWKI-8271ac6a-e858-4db5-b391-bd29e949631f.json b/src/enm/study-NWKI-8271ac6a-e858-4db5-b391-bd29e949631f.json
new file mode 100644
index 0000000..2f202cd
--- /dev/null
+++ b/src/enm/study-NWKI-8271ac6a-e858-4db5-b391-bd29e949631f.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-8271ac6a-e858-4db5-b391-bd29e949631f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4551e0f7-e515-3cdb-a099-c2b99b04883d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "loValue": 3.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-827ec00c-a596-4f38-b9ad-08f943876e31.json b/src/enm/study-NWKI-827ec00c-a596-4f38-b9ad-08f943876e31.json
new file mode 100644
index 0000000..5d9af52
--- /dev/null
+++ b/src/enm/study-NWKI-827ec00c-a596-4f38-b9ad-08f943876e31.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-827ec00c-a596-4f38-b9ad-08f943876e31",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7fca9f1b-fb2a-3fa5-a080-21391413787d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn200546k",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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diff --git a/src/enm/study-NWKI-828e1658-5bdd-445f-bbfe-458a9abf7c30.json b/src/enm/study-NWKI-828e1658-5bdd-445f-bbfe-458a9abf7c30.json
new file mode 100644
index 0000000..40c493e
--- /dev/null
+++ b/src/enm/study-NWKI-828e1658-5bdd-445f-bbfe-458a9abf7c30.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-828e1658-5bdd-445f-bbfe-458a9abf7c30",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3db8eb74-b206-31ad-8c1b-3569703c47cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
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+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
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+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-82d881e8-7cd5-4a89-9c16-51987673aad2.json b/src/enm/study-NWKI-82d881e8-7cd5-4a89-9c16-51987673aad2.json
new file mode 100644
index 0000000..00990e9
--- /dev/null
+++ b/src/enm/study-NWKI-82d881e8-7cd5-4a89-9c16-51987673aad2.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-82d881e8-7cd5-4a89-9c16-51987673aad2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f6f54a71-9459-397b-b0f7-b27538cff042"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10.7,
+ "errorValue": 0.7
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+ ]
+}
diff --git a/src/enm/study-NWKI-82ed7739-5461-4950-8043-2cad14dd4a4a.json b/src/enm/study-NWKI-82ed7739-5461-4950-8043-2cad14dd4a4a.json
new file mode 100644
index 0000000..2d1d067
--- /dev/null
+++ b/src/enm/study-NWKI-82ed7739-5461-4950-8043-2cad14dd4a4a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-82ed7739-5461-4950-8043-2cad14dd4a4a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4832de65-5a92-3849-8061-729a2d83017e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "reliability": {
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+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8418de03-f2af-4c3f-821a-6f6420a4d1a2.json b/src/enm/study-NWKI-8418de03-f2af-4c3f-821a-6f6420a4d1a2.json
new file mode 100644
index 0000000..0f8f646
--- /dev/null
+++ b/src/enm/study-NWKI-8418de03-f2af-4c3f-821a-6f6420a4d1a2.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-8418de03-f2af-4c3f-821a-6f6420a4d1a2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2e056907-7ac9-3b13-a599-ee10f2548d78"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1107/S0108768105030570",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 11,
+ "errorValue": 2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-846ab593-674b-4f4b-9012-257e7bfa77fe.json b/src/enm/study-NWKI-846ab593-674b-4f4b-9012-257e7bfa77fe.json
new file mode 100644
index 0000000..5e89532
--- /dev/null
+++ b/src/enm/study-NWKI-846ab593-674b-4f4b-9012-257e7bfa77fe.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-846ab593-674b-4f4b-9012-257e7bfa77fe",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 500,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 69
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-854d40ae-447a-4eaa-99bc-1e08310325ea.json b/src/enm/study-NWKI-854d40ae-447a-4eaa-99bc-1e08310325ea.json
new file mode 100644
index 0000000..2a9a0eb
--- /dev/null
+++ b/src/enm/study-NWKI-854d40ae-447a-4eaa-99bc-1e08310325ea.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-854d40ae-447a-4eaa-99bc-1e08310325ea",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9a41ca03-303d-3116-89fb-2335cc1bad2d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 250
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-85588bf6-8956-4f51-84e8-96a3d38ea4ce.json b/src/enm/study-NWKI-85588bf6-8956-4f51-84e8-96a3d38ea4ce.json
new file mode 100644
index 0000000..28f180e
--- /dev/null
+++ b/src/enm/study-NWKI-85588bf6-8956-4f51-84e8-96a3d38ea4ce.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-85588bf6-8956-4f51-84e8-96a3d38ea4ce",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-db562080-5286-327a-b813-6775c437385e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DRCOOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-86218576-1edf-4bb7-9778-f931ffe7cff1.json b/src/enm/study-NWKI-86218576-1edf-4bb7-9778-f931ffe7cff1.json
new file mode 100644
index 0000000..a3602ff
--- /dev/null
+++ b/src/enm/study-NWKI-86218576-1edf-4bb7-9778-f931ffe7cff1.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-86218576-1edf-4bb7-9778-f931ffe7cff1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-758c06ae-dc1f-3cbe-a409-91d14e5113d1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DED-2DVT750"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Ethylene_Diamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "NCCN"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ethylene_Diamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-864c1767-bf3b-400e-8c1e-9fee4a997f6f.json b/src/enm/study-NWKI-864c1767-bf3b-400e-8c1e-9fee4a997f6f.json
new file mode 100644
index 0000000..86171a2
--- /dev/null
+++ b/src/enm/study-NWKI-864c1767-bf3b-400e-8c1e-9fee4a997f6f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-864c1767-bf3b-400e-8c1e-9fee4a997f6f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-04887adf-9687-3699-8054-e7e3f695e6db"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-868e0d65-60b4-4614-85ed-8c2d7e5590cc.json b/src/enm/study-NWKI-868e0d65-60b4-4614-85ed-8c2d7e5590cc.json
new file mode 100644
index 0000000..990d938
--- /dev/null
+++ b/src/enm/study-NWKI-868e0d65-60b4-4614-85ed-8c2d7e5590cc.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-868e0d65-60b4-4614-85ed-8c2d7e5590cc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5a6518a3-ff8d-374b-a070-92a1addafdd7"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 59.6,
+ "errorValue": 19
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-86f24136-cad3-4ddc-bac0-b0bb2eebe856.json b/src/enm/study-NWKI-86f24136-cad3-4ddc-bac0-b0bb2eebe856.json
new file mode 100644
index 0000000..a7800b5
--- /dev/null
+++ b/src/enm/study-NWKI-86f24136-cad3-4ddc-bac0-b0bb2eebe856.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-86f24136-cad3-4ddc-bac0-b0bb2eebe856",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7998492c-3902-3cc2-9f92-cdfae53cfc02"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 50
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8744a8f8-25a3-47c6-94d7-498c06c99f4d.json b/src/enm/study-NWKI-8744a8f8-25a3-47c6-94d7-498c06c99f4d.json
new file mode 100644
index 0000000..3b190af
--- /dev/null
+++ b/src/enm/study-NWKI-8744a8f8-25a3-47c6-94d7-498c06c99f4d.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-8744a8f8-25a3-47c6-94d7-498c06c99f4d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8667bfb7-a5da-3eb0-b9d7-86e2c8f06f19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-875567d3-6661-4f7e-82ff-e95d8dcea8bf.json b/src/enm/study-NWKI-875567d3-6661-4f7e-82ff-e95d8dcea8bf.json
new file mode 100644
index 0000000..23feed6
--- /dev/null
+++ b/src/enm/study-NWKI-875567d3-6661-4f7e-82ff-e95d8dcea8bf.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-875567d3-6661-4f7e-82ff-e95d8dcea8bf",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-694f4202-c0ba-3ed9-a0f3-0a5ccba9e9c1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 137
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-876f5e02-52db-4875-bc48-276f952c83b3.json b/src/enm/study-NWKI-876f5e02-52db-4875-bc48-276f952c83b3.json
new file mode 100644
index 0000000..9c7dd84
--- /dev/null
+++ b/src/enm/study-NWKI-876f5e02-52db-4875-bc48-276f952c83b3.json
@@ -0,0 +1,52 @@
+{
+ "uuid": "NWKI-876f5e02-52db-4875-bc48-276f952c83b3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93603a1-8e0d-372a-8acf-48533b86ecb5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 45
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-87933ab9-91b3-4290-b570-6b478504bd26.json b/src/enm/study-NWKI-87933ab9-91b3-4290-b570-6b478504bd26.json
new file mode 100644
index 0000000..4e23810
--- /dev/null
+++ b/src/enm/study-NWKI-87933ab9-91b3-4290-b570-6b478504bd26.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-87933ab9-91b3-4290-b570-6b478504bd26",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-879cace7-705a-4cc6-a1ac-db71577547e7.json b/src/enm/study-NWKI-879cace7-705a-4cc6-a1ac-db71577547e7.json
new file mode 100644
index 0000000..b589dfe
--- /dev/null
+++ b/src/enm/study-NWKI-879cace7-705a-4cc6-a1ac-db71577547e7.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-879cace7-705a-4cc6-a1ac-db71577547e7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52e8adb0-6aba-3e7f-bc0c-85cb36c394a2"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 0.0,
+ "upQualifier": "<=",
+ "upValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-87c16072-a28c-4369-947b-434dc7c94927.json b/src/enm/study-NWKI-87c16072-a28c-4369-947b-434dc7c94927.json
new file mode 100644
index 0000000..d2aec3c
--- /dev/null
+++ b/src/enm/study-NWKI-87c16072-a28c-4369-947b-434dc7c94927.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-87c16072-a28c-4369-947b-434dc7c94927",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f9f316e8-e8a9-37f9-877f-86519b3af20e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Protamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Protamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-884fb0d7-c429-49d6-ba3a-904e1fa119e2.json b/src/enm/study-NWKI-884fb0d7-c429-49d6-ba3a-904e1fa119e2.json
new file mode 100644
index 0000000..7968611
--- /dev/null
+++ b/src/enm/study-NWKI-884fb0d7-c429-49d6-ba3a-904e1fa119e2.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-884fb0d7-c429-49d6-ba3a-904e1fa119e2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d8f70c6c-3496-3ad3-8ab3-e4f08a178d30"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 91
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-88797747-443e-44b0-90a0-ba8ffcf9365a.json b/src/enm/study-NWKI-88797747-443e-44b0-90a0-ba8ffcf9365a.json
new file mode 100644
index 0000000..cb9591b
--- /dev/null
+++ b/src/enm/study-NWKI-88797747-443e-44b0-90a0-ba8ffcf9365a.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-88797747-443e-44b0-90a0-ba8ffcf9365a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 5,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8888d86f-a6b7-4cd4-a7b0-e650efad27da.json b/src/enm/study-NWKI-8888d86f-a6b7-4cd4-a7b0-e650efad27da.json
new file mode 100644
index 0000000..491a843
--- /dev/null
+++ b/src/enm/study-NWKI-8888d86f-a6b7-4cd4-a7b0-e650efad27da.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-8888d86f-a6b7-4cd4-a7b0-e650efad27da",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a2d5a729-4ed1-3f1b-a5fd-3bd090a48aa5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 190,
+ "errorValue": 9
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-88a68961-fb9d-4409-89aa-295d10bf63b2.json b/src/enm/study-NWKI-88a68961-fb9d-4409-89aa-295d10bf63b2.json
new file mode 100644
index 0000000..fbb2dd0
--- /dev/null
+++ b/src/enm/study-NWKI-88a68961-fb9d-4409-89aa-295d10bf63b2.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-88a68961-fb9d-4409-89aa-295d10bf63b2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 150,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-88ebd7b5-2689-4ac1-86cc-b8b790bd5f9a.json b/src/enm/study-NWKI-88ebd7b5-2689-4ac1-86cc-b8b790bd5f9a.json
new file mode 100644
index 0000000..15b0a49
--- /dev/null
+++ b/src/enm/study-NWKI-88ebd7b5-2689-4ac1-86cc-b8b790bd5f9a.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-88ebd7b5-2689-4ac1-86cc-b8b790bd5f9a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 150,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-88eea7d0-463b-4ffb-aeef-8b27912f66a7.json b/src/enm/study-NWKI-88eea7d0-463b-4ffb-aeef-8b27912f66a7.json
new file mode 100644
index 0000000..6d121d5
--- /dev/null
+++ b/src/enm/study-NWKI-88eea7d0-463b-4ffb-aeef-8b27912f66a7.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-88eea7d0-463b-4ffb-aeef-8b27912f66a7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2a046d54-ea47-31b2-a370-e886e5a0a6bb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 33
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-88f9ff3b-4ff7-4ddd-b0c9-de797a65170a.json b/src/enm/study-NWKI-88f9ff3b-4ff7-4ddd-b0c9-de797a65170a.json
new file mode 100644
index 0000000..dccdebf
--- /dev/null
+++ b/src/enm/study-NWKI-88f9ff3b-4ff7-4ddd-b0c9-de797a65170a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-88f9ff3b-4ff7-4ddd-b0c9-de797a65170a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7a8cde87-8021-3d12-9dfe-f408dfe81a74"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 21
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8928ffc5-2b1c-42a8-9534-89ba4d50c54d.json b/src/enm/study-NWKI-8928ffc5-2b1c-42a8-9534-89ba4d50c54d.json
new file mode 100644
index 0000000..0f3a14a
--- /dev/null
+++ b/src/enm/study-NWKI-8928ffc5-2b1c-42a8-9534-89ba4d50c54d.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-8928ffc5-2b1c-42a8-9534-89ba4d50c54d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-17c74ed1-b289-3ca1-8477-390a588cb28c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8955d52a-7973-44c8-be98-9b43bb1e135b.json b/src/enm/study-NWKI-8955d52a-7973-44c8-be98-9b43bb1e135b.json
new file mode 100644
index 0000000..c805764
--- /dev/null
+++ b/src/enm/study-NWKI-8955d52a-7973-44c8-be98-9b43bb1e135b.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-8955d52a-7973-44c8-be98-9b43bb1e135b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f926951f-587c-3206-88c9-bd92614da153"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 193,
+ "errorValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-89883f1b-15a0-4ec6-9b78-095a087de0f1.json b/src/enm/study-NWKI-89883f1b-15a0-4ec6-9b78-095a087de0f1.json
new file mode 100644
index 0000000..a673664
--- /dev/null
+++ b/src/enm/study-NWKI-89883f1b-15a0-4ec6-9b78-095a087de0f1.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-89883f1b-15a0-4ec6-9b78-095a087de0f1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a4b3e23-3327-3421-b20a-2e71939b44b1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DGlutamicAcid"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Glutamic_Acid"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "C(CC(=O)O)C(C(=O)O)N"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Glutamic_Acid"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-89c9d590-26e4-4f2d-8439-4bf6c76f7558.json b/src/enm/study-NWKI-89c9d590-26e4-4f2d-8439-4bf6c76f7558.json
new file mode 100644
index 0000000..a66fcd9
--- /dev/null
+++ b/src/enm/study-NWKI-89c9d590-26e4-4f2d-8439-4bf6c76f7558.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-89c9d590-26e4-4f2d-8439-4bf6c76f7558",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-85b50517-fdea-3aa6-abbd-dd506393aaa5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 144
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-89e3d898-31aa-4719-8579-7c93dde6274e.json b/src/enm/study-NWKI-89e3d898-31aa-4719-8579-7c93dde6274e.json
new file mode 100644
index 0000000..cd18866
--- /dev/null
+++ b/src/enm/study-NWKI-89e3d898-31aa-4719-8579-7c93dde6274e.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-89e3d898-31aa-4719-8579-7c93dde6274e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8196e92b-c46d-3c14-9410-e87992810710"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -3.77
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8a80359b-2827-4800-a2ca-fcb5571c0300.json b/src/enm/study-NWKI-8a80359b-2827-4800-a2ca-fcb5571c0300.json
new file mode 100644
index 0000000..cc9dbe6
--- /dev/null
+++ b/src/enm/study-NWKI-8a80359b-2827-4800-a2ca-fcb5571c0300.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-8a80359b-2827-4800-a2ca-fcb5571c0300",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-47d254de-8242-3374-9ed3-085227d473cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -4.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8b3ff259-2009-44f5-9480-f00cb9ae69c8.json b/src/enm/study-NWKI-8b3ff259-2009-44f5-9480-f00cb9ae69c8.json
new file mode 100644
index 0000000..089520d
--- /dev/null
+++ b/src/enm/study-NWKI-8b3ff259-2009-44f5-9480-f00cb9ae69c8.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-8b3ff259-2009-44f5-9480-f00cb9ae69c8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-845bf8fc-788d-38f2-be58-030f27c0d337"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8b87c7de-7545-494f-a082-c16729a18b4f.json b/src/enm/study-NWKI-8b87c7de-7545-494f-a082-c16729a18b4f.json
new file mode 100644
index 0000000..c9f3c17
--- /dev/null
+++ b/src/enm/study-NWKI-8b87c7de-7545-494f-a082-c16729a18b4f.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-8b87c7de-7545-494f-a082-c16729a18b4f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0455b6e1-5203-37bb-a98b-20460acceda1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 3.64
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8b8dfa72-0284-415c-b50c-22b3a8a9b839.json b/src/enm/study-NWKI-8b8dfa72-0284-415c-b50c-22b3a8a9b839.json
new file mode 100644
index 0000000..a2ed076
--- /dev/null
+++ b/src/enm/study-NWKI-8b8dfa72-0284-415c-b50c-22b3a8a9b839.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-8b8dfa72-0284-415c-b50c-22b3a8a9b839",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4358aa69-dec1-387a-b7ea-2238198ccdff"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "ZETA POTENTIAL",
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+ "Remark": null,
+ "Serum": {
+ "loValue": "PBS"
+ },
+ "pH": {
+ "loValue": 7.15
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -27
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8bb3beb0-5e80-4bfe-85ac-99b7aceebcad.json b/src/enm/study-NWKI-8bb3beb0-5e80-4bfe-85ac-99b7aceebcad.json
new file mode 100644
index 0000000..4d6133e
--- /dev/null
+++ b/src/enm/study-NWKI-8bb3beb0-5e80-4bfe-85ac-99b7aceebcad.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-8bb3beb0-5e80-4bfe-85ac-99b7aceebcad",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ae0be5b8-266b-3b6a-825d-55f14b51cc99"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8bbc6716-d975-4f0c-afae-60dab49a06cc.json b/src/enm/study-NWKI-8bbc6716-d975-4f0c-afae-60dab49a06cc.json
new file mode 100644
index 0000000..53846d8
--- /dev/null
+++ b/src/enm/study-NWKI-8bbc6716-d975-4f0c-afae-60dab49a06cc.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-8bbc6716-d975-4f0c-afae-60dab49a06cc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4358aa69-dec1-387a-b7ea-2238198ccdff"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "sfMEM"
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 106
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8c25ade1-6431-4040-a52d-cb234978487e.json b/src/enm/study-NWKI-8c25ade1-6431-4040-a52d-cb234978487e.json
new file mode 100644
index 0000000..aee76c8
--- /dev/null
+++ b/src/enm/study-NWKI-8c25ade1-6431-4040-a52d-cb234978487e.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-8c25ade1-6431-4040-a52d-cb234978487e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-afc33b0f-f6ce-3c1b-8a3d-cede13515323"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -7.15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8d2443b8-7a23-4c59-988b-fd99323e4e37.json b/src/enm/study-NWKI-8d2443b8-7a23-4c59-988b-fd99323e4e37.json
new file mode 100644
index 0000000..891b834
--- /dev/null
+++ b/src/enm/study-NWKI-8d2443b8-7a23-4c59-988b-fd99323e4e37.json
@@ -0,0 +1,54 @@
+{
+ "uuid": "NWKI-8d2443b8-7a23-4c59-988b-fd99323e4e37",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ea48c37d-840a-30d2-9740-1198a7e2c3b6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_BOILING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000257",
+ "title": "4.3 Boiling point"
+ },
+ "endpoint": "Boiling Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Boiling point",
+ "conditions": {
+ "Atm. Pressure": null,
+ "Decomposition": null
+ },
+ "result": {
+ "unit": "Celsius",
+ "loValue": 2230
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8d772138-7e9c-4e23-a9ad-844af1713aa0.json b/src/enm/study-NWKI-8d772138-7e9c-4e23-a9ad-844af1713aa0.json
new file mode 100644
index 0000000..7e54940
--- /dev/null
+++ b/src/enm/study-NWKI-8d772138-7e9c-4e23-a9ad-844af1713aa0.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-8d772138-7e9c-4e23-a9ad-844af1713aa0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8c5b9350-2c03-3173-9615-cabfbe6929c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 0
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8db075a8-2314-4897-8bd6-c0afa961884e.json b/src/enm/study-NWKI-8db075a8-2314-4897-8bd6-c0afa961884e.json
new file mode 100644
index 0000000..efb4054
--- /dev/null
+++ b/src/enm/study-NWKI-8db075a8-2314-4897-8bd6-c0afa961884e.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-8db075a8-2314-4897-8bd6-c0afa961884e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7998492c-3902-3cc2-9f92-cdfae53cfc02"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 10,
+ "unit": "m"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8ddf2a3a-2988-4255-8188-0c48855e7f58.json b/src/enm/study-NWKI-8ddf2a3a-2988-4255-8188-0c48855e7f58.json
new file mode 100644
index 0000000..6dd5838
--- /dev/null
+++ b/src/enm/study-NWKI-8ddf2a3a-2988-4255-8188-0c48855e7f58.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-8ddf2a3a-2988-4255-8188-0c48855e7f58",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f40bfb8a-1280-35a2-866c-42b5a3ce13e7"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.64
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8dfaf1c8-d49d-4280-ab04-6f55ce644942.json b/src/enm/study-NWKI-8dfaf1c8-d49d-4280-ab04-6f55ce644942.json
new file mode 100644
index 0000000..27ff0ca
--- /dev/null
+++ b/src/enm/study-NWKI-8dfaf1c8-d49d-4280-ab04-6f55ce644942.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-8dfaf1c8-d49d-4280-ab04-6f55ce644942",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8e70a872-3806-4bf9-a8c9-ed59fbd3ca45.json b/src/enm/study-NWKI-8e70a872-3806-4bf9-a8c9-ed59fbd3ca45.json
new file mode 100644
index 0000000..2155a13
--- /dev/null
+++ b/src/enm/study-NWKI-8e70a872-3806-4bf9-a8c9-ed59fbd3ca45.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-8e70a872-3806-4bf9-a8c9-ed59fbd3ca45",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5adec23a-ab6a-350e-baec-cd088a4667d5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -16.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8e945981-32ca-4c56-b481-45f7b8c630bd.json b/src/enm/study-NWKI-8e945981-32ca-4c56-b481-45f7b8c630bd.json
new file mode 100644
index 0000000..46db193
--- /dev/null
+++ b/src/enm/study-NWKI-8e945981-32ca-4c56-b481-45f7b8c630bd.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-8e945981-32ca-4c56-b481-45f7b8c630bd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 3.12,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8ea9b598-a5d6-472a-b449-53e48222d54d.json b/src/enm/study-NWKI-8ea9b598-a5d6-472a-b449-53e48222d54d.json
new file mode 100644
index 0000000..4d5f285
--- /dev/null
+++ b/src/enm/study-NWKI-8ea9b598-a5d6-472a-b449-53e48222d54d.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-8ea9b598-a5d6-472a-b449-53e48222d54d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-863267cf-faf0-349b-8046-6074d2e718b5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.soilbio.2013.01.016",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 14
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-8f580200-09f2-41bb-b4e7-c374edca92fb.json b/src/enm/study-NWKI-8f580200-09f2-41bb-b4e7-c374edca92fb.json
new file mode 100644
index 0000000..a938cf9
--- /dev/null
+++ b/src/enm/study-NWKI-8f580200-09f2-41bb-b4e7-c374edca92fb.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-8f580200-09f2-41bb-b4e7-c374edca92fb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8090df08-f0f9-3c2f-8769-b51c2adaffc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 4.98,
+ "errorValue": 0.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-90015aaf-7a19-4778-8890-4600221b8e7c.json b/src/enm/study-NWKI-90015aaf-7a19-4778-8890-4600221b8e7c.json
new file mode 100644
index 0000000..f1bc153
--- /dev/null
+++ b/src/enm/study-NWKI-90015aaf-7a19-4778-8890-4600221b8e7c.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-90015aaf-7a19-4778-8890-4600221b8e7c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-90087566-2c17-4376-8083-810274cbf918.json b/src/enm/study-NWKI-90087566-2c17-4376-8083-810274cbf918.json
new file mode 100644
index 0000000..ade4281
--- /dev/null
+++ b/src/enm/study-NWKI-90087566-2c17-4376-8083-810274cbf918.json
@@ -0,0 +1,52 @@
+{
+ "uuid": "NWKI-90087566-2c17-4376-8083-810274cbf918",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93603a1-8e0d-372a-8acf-48533b86ecb5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
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+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
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diff --git a/src/enm/study-NWKI-905cb971-3ccb-4db3-ae56-fc94178df572.json b/src/enm/study-NWKI-905cb971-3ccb-4db3-ae56-fc94178df572.json
new file mode 100644
index 0000000..a38ae80
--- /dev/null
+++ b/src/enm/study-NWKI-905cb971-3ccb-4db3-ae56-fc94178df572.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-905cb971-3ccb-4db3-ae56-fc94178df572",
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+ "uuid": "NWKI-ede0d5b5-191a-3003-ac70-a97397ea7bb2"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "TEM"
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+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
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+}
diff --git a/src/enm/study-NWKI-90819c5d-2b87-424d-9ded-af4f9f46c16f.json b/src/enm/study-NWKI-90819c5d-2b87-424d-9ded-af4f9f46c16f.json
new file mode 100644
index 0000000..b124ab9
--- /dev/null
+++ b/src/enm/study-NWKI-90819c5d-2b87-424d-9ded-af4f9f46c16f.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-90819c5d-2b87-424d-9ded-af4f9f46c16f",
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+ "year": "0",
+ "owner": "NanoWiki"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
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+ "endpoint": "Unknown",
+ "guideline": [
+ ""
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new file mode 100644
index 0000000..de5695d
--- /dev/null
+++ b/src/enm/study-NWKI-90bd6e98-90e7-4dd7-88cf-41608544e1fe.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-90bd6e98-90e7-4dd7-88cf-41608544e1fe",
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
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+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
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diff --git a/src/enm/study-NWKI-91102148-62b9-4896-a4a3-f379046ea916.json b/src/enm/study-NWKI-91102148-62b9-4896-a4a3-f379046ea916.json
new file mode 100644
index 0000000..0e5d002
--- /dev/null
+++ b/src/enm/study-NWKI-91102148-62b9-4896-a4a3-f379046ea916.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-91102148-62b9-4896-a4a3-f379046ea916",
+ "owner": {
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+ "uuid": "NWKI-0b16e14c-47ab-3075-afc4-0713d06aa54c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
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+ },
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+ "TESTMAT_FORM": null
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+ },
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+ "SEQ_NUM": null
+ },
+ "result": {
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+ }
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+}
diff --git a/src/enm/study-NWKI-913c2e41-919b-47e9-ba92-572ed92cdfe1.json b/src/enm/study-NWKI-913c2e41-919b-47e9-ba92-572ed92cdfe1.json
new file mode 100644
index 0000000..becfbee
--- /dev/null
+++ b/src/enm/study-NWKI-913c2e41-919b-47e9-ba92-572ed92cdfe1.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-913c2e41-919b-47e9-ba92-572ed92cdfe1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-994226ce-df01-3717-b45d-376f645a8d47"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
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+ },
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+ },
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+ "loValue": 3.14
+ }
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+ ]
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diff --git a/src/enm/study-NWKI-92592b26-8cd8-49ed-b336-c4a26da733f9.json b/src/enm/study-NWKI-92592b26-8cd8-49ed-b336-c4a26da733f9.json
new file mode 100644
index 0000000..4809823
--- /dev/null
+++ b/src/enm/study-NWKI-92592b26-8cd8-49ed-b336-c4a26da733f9.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-92592b26-8cd8-49ed-b336-c4a26da733f9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ab2d4bdd-7a72-3e26-8552-5bb6027896bb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "effects": [
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+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
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+ "SEQ_NUM": null
+ },
+ "result": {
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+ "loValue": 665,
+ "errorValue": 46
+ }
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+}
diff --git a/src/enm/study-NWKI-928470d1-bec3-4480-a7f7-65e67c7e5c92.json b/src/enm/study-NWKI-928470d1-bec3-4480-a7f7-65e67c7e5c92.json
new file mode 100644
index 0000000..d029259
--- /dev/null
+++ b/src/enm/study-NWKI-928470d1-bec3-4480-a7f7-65e67c7e5c92.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-928470d1-bec3-4480-a7f7-65e67c7e5c92",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3db8eb74-b206-31ad-8c1b-3569703c47cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
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+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9336a9a1-50e1-4b0c-ac57-c4e25c1b6370.json b/src/enm/study-NWKI-9336a9a1-50e1-4b0c-ac57-c4e25c1b6370.json
new file mode 100644
index 0000000..4b60f31
--- /dev/null
+++ b/src/enm/study-NWKI-9336a9a1-50e1-4b0c-ac57-c4e25c1b6370.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-9336a9a1-50e1-4b0c-ac57-c4e25c1b6370",
+ "owner": {
+ "substance": {
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+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
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+ "year": "0",
+ "owner": "NanoWiki"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "reliability": {
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diff --git a/src/enm/study-NWKI-933acfd4-a3d4-4e99-90c6-531e2f9e2356.json b/src/enm/study-NWKI-933acfd4-a3d4-4e99-90c6-531e2f9e2356.json
new file mode 100644
index 0000000..e186ccb
--- /dev/null
+++ b/src/enm/study-NWKI-933acfd4-a3d4-4e99-90c6-531e2f9e2356.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-933acfd4-a3d4-4e99-90c6-531e2f9e2356",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f9f316e8-e8a9-37f9-877f-86519b3af20e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "SAMPLING": null,
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+ },
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+ "effects": [
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+ "conditions": {
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+ "DESCRIPTION": {
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+ "textValue": "FITC"
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diff --git a/src/enm/study-NWKI-934c5c1a-86df-4901-9e9c-bf4a2ca93465.json b/src/enm/study-NWKI-934c5c1a-86df-4901-9e9c-bf4a2ca93465.json
new file mode 100644
index 0000000..25c7d2a
--- /dev/null
+++ b/src/enm/study-NWKI-934c5c1a-86df-4901-9e9c-bf4a2ca93465.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-934c5c1a-86df-4901-9e9c-bf4a2ca93465",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a33b26f0-2fc7-3aa1-9dd6-27380f725bfe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "conditions": {
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+ "loValue": 2.49
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-93603f88-ae1a-4819-843d-c38db4ce16c1.json b/src/enm/study-NWKI-93603f88-ae1a-4819-843d-c38db4ce16c1.json
new file mode 100644
index 0000000..699edd8
--- /dev/null
+++ b/src/enm/study-NWKI-93603f88-ae1a-4819-843d-c38db4ce16c1.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-93603f88-ae1a-4819-843d-c38db4ce16c1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-245fc9be-5928-354e-8fd1-ae88663923f1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 21
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-93734b2b-c7e0-4cfc-936b-bd0aa4f5f31e.json b/src/enm/study-NWKI-93734b2b-c7e0-4cfc-936b-bd0aa4f5f31e.json
new file mode 100644
index 0000000..cb953d8
--- /dev/null
+++ b/src/enm/study-NWKI-93734b2b-c7e0-4cfc-936b-bd0aa4f5f31e.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-93734b2b-c7e0-4cfc-936b-bd0aa4f5f31e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fd891814-04d2-30bc-a0b6-cc3149bf75ec"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 17
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-93a75471-e455-444d-a639-c69931789c11.json b/src/enm/study-NWKI-93a75471-e455-444d-a639-c69931789c11.json
new file mode 100644
index 0000000..98197ae
--- /dev/null
+++ b/src/enm/study-NWKI-93a75471-e455-444d-a639-c69931789c11.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-93a75471-e455-444d-a639-c69931789c11",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-18aebb90-aacb-3e15-b516-4d3683e9c27b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "BET",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-93d38c82-285c-4800-831e-0e4ccdb61c13.json b/src/enm/study-NWKI-93d38c82-285c-4800-831e-0e4ccdb61c13.json
new file mode 100644
index 0000000..53679f1
--- /dev/null
+++ b/src/enm/study-NWKI-93d38c82-285c-4800-831e-0e4ccdb61c13.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-93d38c82-285c-4800-831e-0e4ccdb61c13",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8c5b9350-2c03-3173-9615-cabfbe6929c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-941a3ff6-4f05-493d-ad80-2ec04ab35035.json b/src/enm/study-NWKI-941a3ff6-4f05-493d-ad80-2ec04ab35035.json
new file mode 100644
index 0000000..6ce8d37
--- /dev/null
+++ b/src/enm/study-NWKI-941a3ff6-4f05-493d-ad80-2ec04ab35035.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-941a3ff6-4f05-493d-ad80-2ec04ab35035",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ec00c05f-0b35-3c5a-b16f-7a3560213764"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 38
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-94f8825d-c863-4642-9a16-cc7b64ed4253.json b/src/enm/study-NWKI-94f8825d-c863-4642-9a16-cc7b64ed4253.json
new file mode 100644
index 0000000..d5c0f62
--- /dev/null
+++ b/src/enm/study-NWKI-94f8825d-c863-4642-9a16-cc7b64ed4253.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-94f8825d-c863-4642-9a16-cc7b64ed4253",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bbb67d89-eaff-38ab-ba4f-403bfb064a0c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-94fd6054-3823-4ca0-b190-a54a3c38cc49.json b/src/enm/study-NWKI-94fd6054-3823-4ca0-b190-a54a3c38cc49.json
new file mode 100644
index 0000000..94b94cf
--- /dev/null
+++ b/src/enm/study-NWKI-94fd6054-3823-4ca0-b190-a54a3c38cc49.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-94fd6054-3823-4ca0-b190-a54a3c38cc49",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7181cc57-548a-3117-b59a-bfff2933c0b5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2015.1017022",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Diameter",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Diameter",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 180
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-950a3601-d327-49a5-aaa2-f30b2e8f3341.json b/src/enm/study-NWKI-950a3601-d327-49a5-aaa2-f30b2e8f3341.json
new file mode 100644
index 0000000..fd89d74
--- /dev/null
+++ b/src/enm/study-NWKI-950a3601-d327-49a5-aaa2-f30b2e8f3341.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-950a3601-d327-49a5-aaa2-f30b2e8f3341",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3a3b2bcd-8284-37dc-a619-56ffbd7ebd68"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn2021056",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 27.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-95983ce9-209e-472b-b9dd-3cb5ef932993.json b/src/enm/study-NWKI-95983ce9-209e-472b-b9dd-3cb5ef932993.json
new file mode 100644
index 0000000..627e8f8
--- /dev/null
+++ b/src/enm/study-NWKI-95983ce9-209e-472b-b9dd-3cb5ef932993.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-95983ce9-209e-472b-b9dd-3cb5ef932993",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4358aa69-dec1-387a-b7ea-2238198ccdff"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "Serum": {
+ "loValue": "cMEM"
+ },
+ "pH": {
+ "loValue": 7.26
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -19
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-95c1843c-939a-4733-93f9-ec825c192e00.json b/src/enm/study-NWKI-95c1843c-939a-4733-93f9-ec825c192e00.json
new file mode 100644
index 0000000..71d13ff
--- /dev/null
+++ b/src/enm/study-NWKI-95c1843c-939a-4733-93f9-ec825c192e00.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-95c1843c-939a-4733-93f9-ec825c192e00",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 5,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-95c4fa9c-3b2f-4864-8512-8bac993fa381.json b/src/enm/study-NWKI-95c4fa9c-3b2f-4864-8512-8bac993fa381.json
new file mode 100644
index 0000000..5b22bac
--- /dev/null
+++ b/src/enm/study-NWKI-95c4fa9c-3b2f-4864-8512-8bac993fa381.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-95c4fa9c-3b2f-4864-8512-8bac993fa381",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-82c12809-d7af-3061-a531-1db744c521f0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 0.766
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-96076900-e780-4903-b87b-e239a69a3691.json b/src/enm/study-NWKI-96076900-e780-4903-b87b-e239a69a3691.json
new file mode 100644
index 0000000..86d164f
--- /dev/null
+++ b/src/enm/study-NWKI-96076900-e780-4903-b87b-e239a69a3691.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-96076900-e780-4903-b87b-e239a69a3691",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bbce341e-3e4d-37f9-a891-5462ada32180"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 68
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-961c71f1-8e7a-4590-aa48-4562e0561b3f.json b/src/enm/study-NWKI-961c71f1-8e7a-4590-aa48-4562e0561b3f.json
new file mode 100644
index 0000000..1d0a377
--- /dev/null
+++ b/src/enm/study-NWKI-961c71f1-8e7a-4590-aa48-4562e0561b3f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-961c71f1-8e7a-4590-aa48-4562e0561b3f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d8f70c6c-3496-3ad3-8ab3-e4f08a178d30"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 250,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-96837237-0aba-461d-be45-d3ddab98b478.json b/src/enm/study-NWKI-96837237-0aba-461d-be45-d3ddab98b478.json
new file mode 100644
index 0000000..20eaad8
--- /dev/null
+++ b/src/enm/study-NWKI-96837237-0aba-461d-be45-d3ddab98b478.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-96837237-0aba-461d-be45-d3ddab98b478",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-eccbd5c0-7cdb-3dc5-b9e3-8a7e17b3915a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -67.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-968d1718-be47-4ee5-a2df-f5da138e2b81.json b/src/enm/study-NWKI-968d1718-be47-4ee5-a2df-f5da138e2b81.json
new file mode 100644
index 0000000..6dd5ab6
--- /dev/null
+++ b/src/enm/study-NWKI-968d1718-be47-4ee5-a2df-f5da138e2b81.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-968d1718-be47-4ee5-a2df-f5da138e2b81",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-47d254de-8242-3374-9ed3-085227d473cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG-2DED-2DAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PEG"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PEG"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-96a0b84b-a6a7-4501-adc9-54c01507d896.json b/src/enm/study-NWKI-96a0b84b-a6a7-4501-adc9-54c01507d896.json
new file mode 100644
index 0000000..a0e52fd
--- /dev/null
+++ b/src/enm/study-NWKI-96a0b84b-a6a7-4501-adc9-54c01507d896.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-96a0b84b-a6a7-4501-adc9-54c01507d896",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-96b1d137-5f38-484c-9d0b-62e62dcf98ac.json b/src/enm/study-NWKI-96b1d137-5f38-484c-9d0b-62e62dcf98ac.json
new file mode 100644
index 0000000..6aa2c66
--- /dev/null
+++ b/src/enm/study-NWKI-96b1d137-5f38-484c-9d0b-62e62dcf98ac.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-96b1d137-5f38-484c-9d0b-62e62dcf98ac",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-47d254de-8242-3374-9ed3-085227d473cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-97080abf-0df0-4681-a038-af98d3e0fec5.json b/src/enm/study-NWKI-97080abf-0df0-4681-a038-af98d3e0fec5.json
new file mode 100644
index 0000000..4a889dc
--- /dev/null
+++ b/src/enm/study-NWKI-97080abf-0df0-4681-a038-af98d3e0fec5.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-97080abf-0df0-4681-a038-af98d3e0fec5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-56d49cc3-4a76-354b-9a77-4b2ecb2dbef0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 55
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9729ff94-c90e-4b2a-bc4a-6b45455ca4a2.json b/src/enm/study-NWKI-9729ff94-c90e-4b2a-bc4a-6b45455ca4a2.json
new file mode 100644
index 0000000..3c67836
--- /dev/null
+++ b/src/enm/study-NWKI-9729ff94-c90e-4b2a-bc4a-6b45455ca4a2.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-9729ff94-c90e-4b2a-bc4a-6b45455ca4a2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7998492c-3902-3cc2-9f92-cdfae53cfc02"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 1,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-975f2041-3c03-47a0-8dea-cdcf547288e4.json b/src/enm/study-NWKI-975f2041-3c03-47a0-8dea-cdcf547288e4.json
new file mode 100644
index 0000000..32898b9
--- /dev/null
+++ b/src/enm/study-NWKI-975f2041-3c03-47a0-8dea-cdcf547288e4.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-975f2041-3c03-47a0-8dea-cdcf547288e4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3fb9be70-8c15-3b78-94e7-5c3c88799818"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DED"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Ethylene_Diamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "NCCN"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ethylene_Diamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-97d7329d-ede3-47f2-bae7-88072c73ac5e.json b/src/enm/study-NWKI-97d7329d-ede3-47f2-bae7-88072c73ac5e.json
new file mode 100644
index 0000000..30840dc
--- /dev/null
+++ b/src/enm/study-NWKI-97d7329d-ede3-47f2-bae7-88072c73ac5e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-97d7329d-ede3-47f2-bae7-88072c73ac5e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3c8c8bb2-416f-3bff-862a-8433538cd4c5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 0.0,
+ "upQualifier": "<=",
+ "upValue": 25
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-97f54c1c-0ec7-4273-a92d-245c3efa4b33.json b/src/enm/study-NWKI-97f54c1c-0ec7-4273-a92d-245c3efa4b33.json
new file mode 100644
index 0000000..b701ff8
--- /dev/null
+++ b/src/enm/study-NWKI-97f54c1c-0ec7-4273-a92d-245c3efa4b33.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-97f54c1c-0ec7-4273-a92d-245c3efa4b33",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3fb9be70-8c15-3b78-94e7-5c3c88799818"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
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+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "loQualifier": " ",
+ "loValue": "PVA-2DED"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
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+ "Remark": null,
+ "TYPE": {
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+ "loValue": "COATING"
+ }
+ },
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+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9833b4a9-d932-4d79-846c-1a26b3659885.json b/src/enm/study-NWKI-9833b4a9-d932-4d79-846c-1a26b3659885.json
new file mode 100644
index 0000000..787cc19
--- /dev/null
+++ b/src/enm/study-NWKI-9833b4a9-d932-4d79-846c-1a26b3659885.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-9833b4a9-d932-4d79-846c-1a26b3659885",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e866549e-38cf-3b98-a0b1-a483e275d261"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-98d15c68-20d6-4106-a239-99dcdb3d6c9c.json b/src/enm/study-NWKI-98d15c68-20d6-4106-a239-99dcdb3d6c9c.json
new file mode 100644
index 0000000..7ad2811
--- /dev/null
+++ b/src/enm/study-NWKI-98d15c68-20d6-4106-a239-99dcdb3d6c9c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-98d15c68-20d6-4106-a239-99dcdb3d6c9c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0b663f5f-1386-3cc5-ba6b-9ff2bb39d4ff"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/gt.2011.95",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ },
+ "interpretation": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 13,
+ "errorValue": 11
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-98ef698c-7c3a-4e90-b8d2-09f1be340f64.json b/src/enm/study-NWKI-98ef698c-7c3a-4e90-b8d2-09f1be340f64.json
new file mode 100644
index 0000000..4888a77
--- /dev/null
+++ b/src/enm/study-NWKI-98ef698c-7c3a-4e90-b8d2-09f1be340f64.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-98ef698c-7c3a-4e90-b8d2-09f1be340f64",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f1cc0abb-2905-3699-be62-b238a21e6bad"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ "Remark": null,
+ "pH": null
+ },
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+ "loQualifier": ">=",
+ "loValue": -35,
+ "upQualifier": "<=",
+ "upValue": 48
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-990dfff9-347f-4340-a32d-f4c62938677f.json b/src/enm/study-NWKI-990dfff9-347f-4340-a32d-f4c62938677f.json
new file mode 100644
index 0000000..6ace092
--- /dev/null
+++ b/src/enm/study-NWKI-990dfff9-347f-4340-a32d-f4c62938677f.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-990dfff9-347f-4340-a32d-f4c62938677f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-82665bf4-5c5e-325a-a7ee-44ff1c6045b7"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10,
+ "errorValue": 2.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-998b320c-18fa-4dc8-9be8-a5644f215528.json b/src/enm/study-NWKI-998b320c-18fa-4dc8-9be8-a5644f215528.json
new file mode 100644
index 0000000..1dc7c03
--- /dev/null
+++ b/src/enm/study-NWKI-998b320c-18fa-4dc8-9be8-a5644f215528.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-998b320c-18fa-4dc8-9be8-a5644f215528",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-895a506b-c331-3576-bf9e-cbcde5822c11"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ },
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+ {
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+ "Remark": null,
+ "Serum": {
+ "loValue": "cMEM"
+ },
+ "pH": {
+ "loValue": 7.21
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9a2cbb96-951d-4d49-b8cc-2bf8e080f558.json b/src/enm/study-NWKI-9a2cbb96-951d-4d49-b8cc-2bf8e080f558.json
new file mode 100644
index 0000000..c18daab
--- /dev/null
+++ b/src/enm/study-NWKI-9a2cbb96-951d-4d49-b8cc-2bf8e080f558.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-9a2cbb96-951d-4d49-b8cc-2bf8e080f558",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
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+ },
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+ },
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9a5a6b0a-6e10-4d89-b987-6984da13de1c.json b/src/enm/study-NWKI-9a5a6b0a-6e10-4d89-b987-6984da13de1c.json
new file mode 100644
index 0000000..07c1aab
--- /dev/null
+++ b/src/enm/study-NWKI-9a5a6b0a-6e10-4d89-b987-6984da13de1c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-9a5a6b0a-6e10-4d89-b987-6984da13de1c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9a5fcbe2-ff72-4d68-92e5-266296adfb3a.json b/src/enm/study-NWKI-9a5fcbe2-ff72-4d68-92e5-266296adfb3a.json
new file mode 100644
index 0000000..01ac79d
--- /dev/null
+++ b/src/enm/study-NWKI-9a5fcbe2-ff72-4d68-92e5-266296adfb3a.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-9a5fcbe2-ff72-4d68-92e5-266296adfb3a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "ZETA POTENTIAL",
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+ "Remark": null,
+ "pH": null
+ },
+ "result": {
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+ "loValue": -53
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9a7836ea-becd-42e4-ab1f-8e90b83a7e2c.json b/src/enm/study-NWKI-9a7836ea-becd-42e4-ab1f-8e90b83a7e2c.json
new file mode 100644
index 0000000..97bcc68
--- /dev/null
+++ b/src/enm/study-NWKI-9a7836ea-becd-42e4-ab1f-8e90b83a7e2c.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-9a7836ea-becd-42e4-ab1f-8e90b83a7e2c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9a41ca03-303d-3116-89fb-2335cc1bad2d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Average Length",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "Average Length",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "μm",
+ "loValue": 1.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9ae54803-8808-4fe9-8036-2539cf8d2e0e.json b/src/enm/study-NWKI-9ae54803-8808-4fe9-8036-2539cf8d2e0e.json
new file mode 100644
index 0000000..8934997
--- /dev/null
+++ b/src/enm/study-NWKI-9ae54803-8808-4fe9-8036-2539cf8d2e0e.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-9ae54803-8808-4fe9-8036-2539cf8d2e0e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4f91db77-4cd0-3482-b989-571d2a9a4228"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ },
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+ },
+ "effects": [
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
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+ "loValue": "Ag"
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+ "Remark": null,
+ "TYPE": {
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ag"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MESCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MES"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SCCS(=O)(=O)[O-].[Na+]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "MES"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9b836306-69bf-4950-8367-fb3b78c80a75.json b/src/enm/study-NWKI-9b836306-69bf-4950-8367-fb3b78c80a75.json
new file mode 100644
index 0000000..7ef9d5b
--- /dev/null
+++ b/src/enm/study-NWKI-9b836306-69bf-4950-8367-fb3b78c80a75.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-9b836306-69bf-4950-8367-fb3b78c80a75",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a968835-50ab-33df-bf5e-42de32d01c15"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9baea477-0a08-49d4-aa31-5a4b6fc7fd35.json b/src/enm/study-NWKI-9baea477-0a08-49d4-aa31-5a4b6fc7fd35.json
new file mode 100644
index 0000000..2bd5b13
--- /dev/null
+++ b/src/enm/study-NWKI-9baea477-0a08-49d4-aa31-5a4b6fc7fd35.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-9baea477-0a08-49d4-aa31-5a4b6fc7fd35",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-80364e0e-be06-3645-a3ae-880ae0edddef"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 30.5,
+ "errorValue": 1.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9bc460f1-dc07-4f51-9b67-5e59b51cfd4e.json b/src/enm/study-NWKI-9bc460f1-dc07-4f51-9b67-5e59b51cfd4e.json
new file mode 100644
index 0000000..0314694
--- /dev/null
+++ b/src/enm/study-NWKI-9bc460f1-dc07-4f51-9b67-5e59b51cfd4e.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-9bc460f1-dc07-4f51-9b67-5e59b51cfd4e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 200,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9bd3843d-1379-49b1-a22b-1aa6fea3b982.json b/src/enm/study-NWKI-9bd3843d-1379-49b1-a22b-1aa6fea3b982.json
new file mode 100644
index 0000000..997a4d7
--- /dev/null
+++ b/src/enm/study-NWKI-9bd3843d-1379-49b1-a22b-1aa6fea3b982.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-9bd3843d-1379-49b1-a22b-1aa6fea3b982",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d8f70c6c-3496-3ad3-8ab3-e4f08a178d30"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 500,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 93
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9cba9eb2-7783-442d-a439-a769095f2a23.json b/src/enm/study-NWKI-9cba9eb2-7783-442d-a439-a769095f2a23.json
new file mode 100644
index 0000000..26dd9ee
--- /dev/null
+++ b/src/enm/study-NWKI-9cba9eb2-7783-442d-a439-a769095f2a23.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-9cba9eb2-7783-442d-a439-a769095f2a23",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5454d5cb-1033-3d6f-a31e-038752525533"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 8,
+ "upQualifier": "<=",
+ "upValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9d557d25-bc4f-4eb4-bf94-4c45d94ee256.json b/src/enm/study-NWKI-9d557d25-bc4f-4eb4-bf94-4c45d94ee256.json
new file mode 100644
index 0000000..df0c4ea
--- /dev/null
+++ b/src/enm/study-NWKI-9d557d25-bc4f-4eb4-bf94-4c45d94ee256.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-9d557d25-bc4f-4eb4-bf94-4c45d94ee256",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-56d49cc3-4a76-354b-9a77-4b2ecb2dbef0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 100
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 23
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9d6b99fd-4b45-4711-8ec3-a69204d695a7.json b/src/enm/study-NWKI-9d6b99fd-4b45-4711-8ec3-a69204d695a7.json
new file mode 100644
index 0000000..5509d0e
--- /dev/null
+++ b/src/enm/study-NWKI-9d6b99fd-4b45-4711-8ec3-a69204d695a7.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-9d6b99fd-4b45-4711-8ec3-a69204d695a7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c2ab6def-8305-3b78-958a-4657b3363e11"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 142
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9d93f359-8aba-4e46-9ad1-2976386169a0.json b/src/enm/study-NWKI-9d93f359-8aba-4e46-9ad1-2976386169a0.json
new file mode 100644
index 0000000..fc249ae
--- /dev/null
+++ b/src/enm/study-NWKI-9d93f359-8aba-4e46-9ad1-2976386169a0.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-9d93f359-8aba-4e46-9ad1-2976386169a0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9e3a1375-4b1b-4380-9394-cb169871a210.json b/src/enm/study-NWKI-9e3a1375-4b1b-4380-9394-cb169871a210.json
new file mode 100644
index 0000000..d4c094a
--- /dev/null
+++ b/src/enm/study-NWKI-9e3a1375-4b1b-4380-9394-cb169871a210.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-9e3a1375-4b1b-4380-9394-cb169871a210",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c8d9772c-e50e-3c71-986c-e45692150d71"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -12
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9f29113f-574a-4ebb-bf4c-bc805d2ed845.json b/src/enm/study-NWKI-9f29113f-574a-4ebb-bf4c-bc805d2ed845.json
new file mode 100644
index 0000000..c80405e
--- /dev/null
+++ b/src/enm/study-NWKI-9f29113f-574a-4ebb-bf4c-bc805d2ed845.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-9f29113f-574a-4ebb-bf4c-bc805d2ed845",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e476955f-97bd-3e4c-8bef-03f56fe1b15b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 28.4,
+ "errorValue": 7.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9f39a0b9-0fc2-41a2-b130-fca0712881ea.json b/src/enm/study-NWKI-9f39a0b9-0fc2-41a2-b130-fca0712881ea.json
new file mode 100644
index 0000000..048295e
--- /dev/null
+++ b/src/enm/study-NWKI-9f39a0b9-0fc2-41a2-b130-fca0712881ea.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-9f39a0b9-0fc2-41a2-b130-fca0712881ea",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-994226ce-df01-3717-b45d-376f645a8d47"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 3.14
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9f4fcd1f-7ab6-4993-9092-f2a266d44bcd.json b/src/enm/study-NWKI-9f4fcd1f-7ab6-4993-9092-f2a266d44bcd.json
new file mode 100644
index 0000000..1f76861
--- /dev/null
+++ b/src/enm/study-NWKI-9f4fcd1f-7ab6-4993-9092-f2a266d44bcd.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-9f4fcd1f-7ab6-4993-9092-f2a266d44bcd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4551e0f7-e515-3cdb-a099-c2b99b04883d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "reliability": {
+ "r_isRobustStudy": "false",
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+ "r_value": null
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-9f50cfff-1264-4196-8cf6-df7e0ea4e3f3.json b/src/enm/study-NWKI-9f50cfff-1264-4196-8cf6-df7e0ea4e3f3.json
new file mode 100644
index 0000000..43b22b2
--- /dev/null
+++ b/src/enm/study-NWKI-9f50cfff-1264-4196-8cf6-df7e0ea4e3f3.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-9f50cfff-1264-4196-8cf6-df7e0ea4e3f3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5adec23a-ab6a-350e-baec-cd088a4667d5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
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+ },
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
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+ "loValue": "CdSe"
+ },
+ "Remark": null,
+ "TYPE": {
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "CdSe"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH-2DAmphPolymer"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Amphiphillic_Polymer"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Amphiphillic_Polymer"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a0041084-f829-4ebd-8708-f0ab1fc548fd.json b/src/enm/study-NWKI-a0041084-f829-4ebd-8708-f0ab1fc548fd.json
new file mode 100644
index 0000000..29dd43f
--- /dev/null
+++ b/src/enm/study-NWKI-a0041084-f829-4ebd-8708-f0ab1fc548fd.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-a0041084-f829-4ebd-8708-f0ab1fc548fd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d63286d0-3205-3216-92ce-e9e2632aca9e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG-2DAminoSPARK680IVM"
+ },
+ "DESCRIPTION": {
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+ "loValue": "PVA"
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+ "ELEMENT_OR_GROUP": {
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+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a0202f3b-8e81-4aac-b85c-b4a9ee597300.json b/src/enm/study-NWKI-a0202f3b-8e81-4aac-b85c-b4a9ee597300.json
new file mode 100644
index 0000000..fc81e0d
--- /dev/null
+++ b/src/enm/study-NWKI-a0202f3b-8e81-4aac-b85c-b4a9ee597300.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-a0202f3b-8e81-4aac-b85c-b4a9ee597300",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5f88a526-3e3f-3da5-8082-8d1da0cdfefa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 150
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a05efe4f-e78d-4d0d-8d5b-8c2a0f123326.json b/src/enm/study-NWKI-a05efe4f-e78d-4d0d-8d5b-8c2a0f123326.json
new file mode 100644
index 0000000..8d2f8dc
--- /dev/null
+++ b/src/enm/study-NWKI-a05efe4f-e78d-4d0d-8d5b-8c2a0f123326.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-a05efe4f-e78d-4d0d-8d5b-8c2a0f123326",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cfea3b7c-ee39-34ef-8349-16b1e7825861"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
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+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DRhodamine-2DProtamine"
+ },
+ "DESCRIPTION": {
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+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
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+ "TYPE": {
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+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a077f85d-f2ee-4b1b-aada-3e194e724e86.json b/src/enm/study-NWKI-a077f85d-f2ee-4b1b-aada-3e194e724e86.json
new file mode 100644
index 0000000..29d3436
--- /dev/null
+++ b/src/enm/study-NWKI-a077f85d-f2ee-4b1b-aada-3e194e724e86.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-a077f85d-f2ee-4b1b-aada-3e194e724e86",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8667bfb7-a5da-3eb0-b9d7-86e2c8f06f19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a08fdecf-eefe-4c5b-8e7c-19bd63a19702.json b/src/enm/study-NWKI-a08fdecf-eefe-4c5b-8e7c-19bd63a19702.json
new file mode 100644
index 0000000..c6d91d9
--- /dev/null
+++ b/src/enm/study-NWKI-a08fdecf-eefe-4c5b-8e7c-19bd63a19702.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-a08fdecf-eefe-4c5b-8e7c-19bd63a19702",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93603a1-8e0d-372a-8acf-48533b86ecb5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 3,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 45
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a0a7dbb4-fe64-4040-940c-62a0f9c8299c.json b/src/enm/study-NWKI-a0a7dbb4-fe64-4040-940c-62a0f9c8299c.json
new file mode 100644
index 0000000..4f11e15
--- /dev/null
+++ b/src/enm/study-NWKI-a0a7dbb4-fe64-4040-940c-62a0f9c8299c.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-a0a7dbb4-fe64-4040-940c-62a0f9c8299c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3db8eb74-b206-31ad-8c1b-3569703c47cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -55
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a0d28be6-62ff-4ced-91ef-cd3fcee39631.json b/src/enm/study-NWKI-a0d28be6-62ff-4ced-91ef-cd3fcee39631.json
new file mode 100644
index 0000000..009494a
--- /dev/null
+++ b/src/enm/study-NWKI-a0d28be6-62ff-4ced-91ef-cd3fcee39631.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-a0d28be6-62ff-4ced-91ef-cd3fcee39631",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ef8660fd-e624-3a94-91bc-ad5a6e47bcf3"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 33
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a0faadeb-60cf-4a7e-b904-1d463f87da8b.json b/src/enm/study-NWKI-a0faadeb-60cf-4a7e-b904-1d463f87da8b.json
new file mode 100644
index 0000000..8873843
--- /dev/null
+++ b/src/enm/study-NWKI-a0faadeb-60cf-4a7e-b904-1d463f87da8b.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-a0faadeb-60cf-4a7e-b904-1d463f87da8b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-758c06ae-dc1f-3cbe-a409-91d14e5113d1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
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+ "Method details": null,
+ "SAMPLING": null,
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DED-2DVT750"
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+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA"
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+ "ELEMENT_OR_GROUP": {
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+ },
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+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a2074d37-5a26-4834-b65e-3816b8210262.json b/src/enm/study-NWKI-a2074d37-5a26-4834-b65e-3816b8210262.json
new file mode 100644
index 0000000..abc6a9b
--- /dev/null
+++ b/src/enm/study-NWKI-a2074d37-5a26-4834-b65e-3816b8210262.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-a2074d37-5a26-4834-b65e-3816b8210262",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ae63c430-7a80-35c3-828d-c859d81ce698"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 4.4,
+ "errorValue": 0.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a24c3d6d-c9f3-4741-9390-285a44c0ee30.json b/src/enm/study-NWKI-a24c3d6d-c9f3-4741-9390-285a44c0ee30.json
new file mode 100644
index 0000000..3e9c656
--- /dev/null
+++ b/src/enm/study-NWKI-a24c3d6d-c9f3-4741-9390-285a44c0ee30.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-a24c3d6d-c9f3-4741-9390-285a44c0ee30",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5172b34a-a6f6-398f-ace6-1d30e6bc9efa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -2.72
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a2790aa9-23c6-4a18-b8a5-6153f6d03feb.json b/src/enm/study-NWKI-a2790aa9-23c6-4a18-b8a5-6153f6d03feb.json
new file mode 100644
index 0000000..15cd41f
--- /dev/null
+++ b/src/enm/study-NWKI-a2790aa9-23c6-4a18-b8a5-6153f6d03feb.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-a2790aa9-23c6-4a18-b8a5-6153f6d03feb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5136670d-2925-31d0-8e12-811f8d67677f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 282,
+ "errorValue": 62
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a2b566c2-10f2-419e-9274-0386e24dff1c.json b/src/enm/study-NWKI-a2b566c2-10f2-419e-9274-0386e24dff1c.json
new file mode 100644
index 0000000..77ef3b8
--- /dev/null
+++ b/src/enm/study-NWKI-a2b566c2-10f2-419e-9274-0386e24dff1c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-a2b566c2-10f2-419e-9274-0386e24dff1c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 200,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a2c0c4c4-72b9-4e53-8d19-74e3540576dc.json b/src/enm/study-NWKI-a2c0c4c4-72b9-4e53-8d19-74e3540576dc.json
new file mode 100644
index 0000000..9aae916
--- /dev/null
+++ b/src/enm/study-NWKI-a2c0c4c4-72b9-4e53-8d19-74e3540576dc.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-a2c0c4c4-72b9-4e53-8d19-74e3540576dc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-56d49cc3-4a76-354b-9a77-4b2ecb2dbef0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a2ddf7c5-e959-4091-a35c-ba626cd0e1fb.json b/src/enm/study-NWKI-a2ddf7c5-e959-4091-a35c-ba626cd0e1fb.json
new file mode 100644
index 0000000..a415df6
--- /dev/null
+++ b/src/enm/study-NWKI-a2ddf7c5-e959-4091-a35c-ba626cd0e1fb.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-a2ddf7c5-e959-4091-a35c-ba626cd0e1fb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-506de59a-ae92-361b-a934-0fdfa41101c0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "SAMPLING": null,
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+ },
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+ },
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+ },
+ "effects": [
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
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+ "loValue": "CLIO-2DVT680-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
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+ },
+ "Remark": null,
+ "TYPE": {
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+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a30dd268-00ac-4e0c-a7e4-b96903513235.json b/src/enm/study-NWKI-a30dd268-00ac-4e0c-a7e4-b96903513235.json
new file mode 100644
index 0000000..361c216
--- /dev/null
+++ b/src/enm/study-NWKI-a30dd268-00ac-4e0c-a7e4-b96903513235.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-a30dd268-00ac-4e0c-a7e4-b96903513235",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-473ed1d8-ae5a-3c80-b3f7-50dbc4fd9a3b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ },
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 9.48,
+ "errorValue": 1.26
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a354f38a-4a3f-4ff0-98fe-68fdca27d5f3.json b/src/enm/study-NWKI-a354f38a-4a3f-4ff0-98fe-68fdca27d5f3.json
new file mode 100644
index 0000000..94e64e1
--- /dev/null
+++ b/src/enm/study-NWKI-a354f38a-4a3f-4ff0-98fe-68fdca27d5f3.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-a354f38a-4a3f-4ff0-98fe-68fdca27d5f3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-34a6262c-7f25-3eea-9dd0-bf1e1df40ca9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ },
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+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "ZETA POTENTIAL",
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+ "Remark": null,
+ "pH": {
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+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 11,
+ "errorValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a3d44087-49c4-40a0-9453-1e60deb312d2.json b/src/enm/study-NWKI-a3d44087-49c4-40a0-9453-1e60deb312d2.json
new file mode 100644
index 0000000..9bc52f4
--- /dev/null
+++ b/src/enm/study-NWKI-a3d44087-49c4-40a0-9453-1e60deb312d2.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-a3d44087-49c4-40a0-9453-1e60deb312d2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7d4e9d59-fb38-37b9-99ec-b150ed7ce133"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SiO2"
+ },
+ "Remark": null,
+ "TYPE": {
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "SiO2"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "APS_Coating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "APS"
+ },
+ "ELEMENT_OR_GROUP": {
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+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "APS"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a3db8c03-15d1-4df0-bd7a-a29fc48585c9.json b/src/enm/study-NWKI-a3db8c03-15d1-4df0-bd7a-a29fc48585c9.json
new file mode 100644
index 0000000..7874c82
--- /dev/null
+++ b/src/enm/study-NWKI-a3db8c03-15d1-4df0-bd7a-a29fc48585c9.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-a3db8c03-15d1-4df0-bd7a-a29fc48585c9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3db8eb74-b206-31ad-8c1b-3569703c47cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 97
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a46036b9-82d3-401d-8618-b8676bd264fc.json b/src/enm/study-NWKI-a46036b9-82d3-401d-8618-b8676bd264fc.json
new file mode 100644
index 0000000..f270ed4
--- /dev/null
+++ b/src/enm/study-NWKI-a46036b9-82d3-401d-8618-b8676bd264fc.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-a46036b9-82d3-401d-8618-b8676bd264fc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e7bdb2a3-0b3f-3a38-8d6b-1babc6d92da1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn2021056",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 19.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a487ab56-09b1-4518-b3da-ee1bd8bf3f25.json b/src/enm/study-NWKI-a487ab56-09b1-4518-b3da-ee1bd8bf3f25.json
new file mode 100644
index 0000000..30eb896
--- /dev/null
+++ b/src/enm/study-NWKI-a487ab56-09b1-4518-b3da-ee1bd8bf3f25.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-a487ab56-09b1-4518-b3da-ee1bd8bf3f25",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7ec086b4-bfe8-3246-9c6c-b3565770315b"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "year": "0",
+ "owner": "NanoWiki"
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+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "result": {
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+ }
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+}
diff --git a/src/enm/study-NWKI-a4be5bbf-d6bc-46c2-9bc6-c8436d9212b3.json b/src/enm/study-NWKI-a4be5bbf-d6bc-46c2-9bc6-c8436d9212b3.json
new file mode 100644
index 0000000..809999e
--- /dev/null
+++ b/src/enm/study-NWKI-a4be5bbf-d6bc-46c2-9bc6-c8436d9212b3.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-a4be5bbf-d6bc-46c2-9bc6-c8436d9212b3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e5b618fd-dd48-3562-9a55-737ac7a68466"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "SAMPLING": null,
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+ "effects": [
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+ "loValue": "PVA-2DPEG-2DED-2DVT750"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PEG"
+ },
+ "ELEMENT_OR_GROUP": {
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+ "TYPE": {
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+ },
+ "result": {
+ "unit": null,
+ "textValue": "PEG"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a5257051-eb42-478e-95d6-3fa1572c63f3.json b/src/enm/study-NWKI-a5257051-eb42-478e-95d6-3fa1572c63f3.json
new file mode 100644
index 0000000..653877a
--- /dev/null
+++ b/src/enm/study-NWKI-a5257051-eb42-478e-95d6-3fa1572c63f3.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-a5257051-eb42-478e-95d6-3fa1572c63f3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0d776d00-aec4-3a75-9eb3-453909fc50ed"
+ },
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "endpoint": "PARTICLE SIZE",
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+ },
+ "result": {
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+ "loValue": 28
+ }
+ }
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+}
diff --git a/src/enm/study-NWKI-a52abca7-ad43-4cee-b5f3-e23c8848b73b.json b/src/enm/study-NWKI-a52abca7-ad43-4cee-b5f3-e23c8848b73b.json
new file mode 100644
index 0000000..7fdbf14
--- /dev/null
+++ b/src/enm/study-NWKI-a52abca7-ad43-4cee-b5f3-e23c8848b73b.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-a52abca7-ad43-4cee-b5f3-e23c8848b73b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ca37d03d-af78-3982-8ca0-76025e71fcf1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "loValue": 2.87
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a5d4f55a-48e0-4401-9f75-ac0c5ceb2f15.json b/src/enm/study-NWKI-a5d4f55a-48e0-4401-9f75-ac0c5ceb2f15.json
new file mode 100644
index 0000000..a3705e1
--- /dev/null
+++ b/src/enm/study-NWKI-a5d4f55a-48e0-4401-9f75-ac0c5ceb2f15.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-a5d4f55a-48e0-4401-9f75-ac0c5ceb2f15",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3b09fdd1-3024-3be3-b1c6-332b44f75f99"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
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+ "endpoint": "Log_Reciprocal_EC50",
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+ "loValue": 2.51
+ }
+ }
+ ]
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diff --git a/src/enm/study-NWKI-a5fe4f02-8837-4fad-a530-b2ac0034e3db.json b/src/enm/study-NWKI-a5fe4f02-8837-4fad-a530-b2ac0034e3db.json
new file mode 100644
index 0000000..ce477a0
--- /dev/null
+++ b/src/enm/study-NWKI-a5fe4f02-8837-4fad-a530-b2ac0034e3db.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-a5fe4f02-8837-4fad-a530-b2ac0034e3db",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4832de65-5a92-3849-8061-729a2d83017e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "Shape",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Anatase"
+ },
+ "effects": [
+ {
+ "endpoint": "SHAPE",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Anatase"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a646b409-1a6d-4fa4-a45e-5033017d227f.json b/src/enm/study-NWKI-a646b409-1a6d-4fa4-a45e-5033017d227f.json
new file mode 100644
index 0000000..bd9bba4
--- /dev/null
+++ b/src/enm/study-NWKI-a646b409-1a6d-4fa4-a45e-5033017d227f.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-a646b409-1a6d-4fa4-a45e-5033017d227f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e834e3f1-8c0d-319e-9bac-21c613bdccd0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn200546k",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "TESTMAT_FORM": null
+ },
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+ "interpretation": {
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+ "endpoint": "PARTICLE SIZE",
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+ },
+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a6636f18-d03e-48a9-8a0c-7c445f8af478.json b/src/enm/study-NWKI-a6636f18-d03e-48a9-8a0c-7c445f8af478.json
new file mode 100644
index 0000000..0932861
--- /dev/null
+++ b/src/enm/study-NWKI-a6636f18-d03e-48a9-8a0c-7c445f8af478.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-a6636f18-d03e-48a9-8a0c-7c445f8af478",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d63286d0-3205-3216-92ce-e9e2632aca9e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
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+ "endpoint": "ATOMIC COMPOSITION",
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+ "ELEMENT_OR_GROUP": {
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+ "loValue": "Fe2O3"
+ },
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+ "TYPE": {
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+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
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+ "loValue": "PVA-2DPEG-2DAminoSPARK680IVM"
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+ "DESCRIPTION": {
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+ "loValue": "Amino_SPARK680_IVM"
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+ "TYPE": {
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+ "loValue": "COATING"
+ }
+ },
+ "result": {
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+ "textValue": "Amino_SPARK680_IVM"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a6a7a56c-486a-4d66-a2f6-021e9a5b93fa.json b/src/enm/study-NWKI-a6a7a56c-486a-4d66-a2f6-021e9a5b93fa.json
new file mode 100644
index 0000000..dfd8125
--- /dev/null
+++ b/src/enm/study-NWKI-a6a7a56c-486a-4d66-a2f6-021e9a5b93fa.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-a6a7a56c-486a-4d66-a2f6-021e9a5b93fa",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-1af17b5b-947a-3fd2-a000-cadf542dea4d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 15,
+ "errorValue": 1.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a6d0db9c-be44-4a13-9c24-f5422885575a.json b/src/enm/study-NWKI-a6d0db9c-be44-4a13-9c24-f5422885575a.json
new file mode 100644
index 0000000..57f3c06
--- /dev/null
+++ b/src/enm/study-NWKI-a6d0db9c-be44-4a13-9c24-f5422885575a.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-a6d0db9c-be44-4a13-9c24-f5422885575a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-11ae9232-1521-31d6-9466-c902c43d94fe"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
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+ },
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ {
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+ "pH": null
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+ "loValue": -9.23
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a6e0ae37-6f1a-403c-9e07-7b9fb9334132.json b/src/enm/study-NWKI-a6e0ae37-6f1a-403c-9e07-7b9fb9334132.json
new file mode 100644
index 0000000..a7d4754
--- /dev/null
+++ b/src/enm/study-NWKI-a6e0ae37-6f1a-403c-9e07-7b9fb9334132.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-a6e0ae37-6f1a-403c-9e07-7b9fb9334132",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d63286d0-3205-3216-92ce-e9e2632aca9e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
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+ "Type of method": null
+ },
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+ },
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+ "pH": null
+ },
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+ "loValue": -15.6
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diff --git a/src/enm/study-NWKI-a7636dce-30ed-41cb-8392-69454c3d7fb0.json b/src/enm/study-NWKI-a7636dce-30ed-41cb-8392-69454c3d7fb0.json
new file mode 100644
index 0000000..e2f092b
--- /dev/null
+++ b/src/enm/study-NWKI-a7636dce-30ed-41cb-8392-69454c3d7fb0.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-a7636dce-30ed-41cb-8392-69454c3d7fb0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0a6e319e-71fc-37f7-b88d-fbda2e07ccc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 500,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
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+ "loValue": 100
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a7c2edb4-81b6-42db-ac24-f886e5ac4c55.json b/src/enm/study-NWKI-a7c2edb4-81b6-42db-ac24-f886e5ac4c55.json
new file mode 100644
index 0000000..9e5c5e1
--- /dev/null
+++ b/src/enm/study-NWKI-a7c2edb4-81b6-42db-ac24-f886e5ac4c55.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-a7c2edb4-81b6-42db-ac24-f886e5ac4c55",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b19125a9-4499-3e0e-aa0c-7792401f4900"
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+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+ "TESTMAT_FORM": null
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+ },
+ "result": {
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+ "loValue": 20
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+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a89bb7de-61c6-416e-8304-e7ec2111b843.json b/src/enm/study-NWKI-a89bb7de-61c6-416e-8304-e7ec2111b843.json
new file mode 100644
index 0000000..a8a9822
--- /dev/null
+++ b/src/enm/study-NWKI-a89bb7de-61c6-416e-8304-e7ec2111b843.json
@@ -0,0 +1,55 @@
+{
+ "uuid": "NWKI-a89bb7de-61c6-416e-8304-e7ec2111b843",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2af8ed34-029d-3644-8327-23a596cfae0d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_MELTING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000256",
+ "title": "4.2 Melting point / freezing point"
+ },
+ "endpoint": "Melting Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "endpoint": "Melting Point",
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+ "Sublimation": null
+ },
+ "result": {
+ "unit": "°C",
+ "loQualifier": ">=",
+ "loValue": 1600
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a9686fa8-19cc-4de9-afd1-bb66d50adc61.json b/src/enm/study-NWKI-a9686fa8-19cc-4de9-afd1-bb66d50adc61.json
new file mode 100644
index 0000000..3c3d23d
--- /dev/null
+++ b/src/enm/study-NWKI-a9686fa8-19cc-4de9-afd1-bb66d50adc61.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-a9686fa8-19cc-4de9-afd1-bb66d50adc61",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ae0be5b8-266b-3b6a-825d-55f14b51cc99"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
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+ "r_purposeFlag": null,
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+ "effects": [
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+ "loValue": "PVA-2DArg7COOH"
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+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a970b210-1925-41f3-82ec-d1191c19ab22.json b/src/enm/study-NWKI-a970b210-1925-41f3-82ec-d1191c19ab22.json
new file mode 100644
index 0000000..b8cf6cb
--- /dev/null
+++ b/src/enm/study-NWKI-a970b210-1925-41f3-82ec-d1191c19ab22.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-a970b210-1925-41f3-82ec-d1191c19ab22",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c3d91296-7c2d-3971-b932-e671f2f83aa8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 3.37,
+ "errorValue": 0.57
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-a994fb96-60a5-4ad0-9cb9-c566c7f0a76e.json b/src/enm/study-NWKI-a994fb96-60a5-4ad0-9cb9-c566c7f0a76e.json
new file mode 100644
index 0000000..b33961a
--- /dev/null
+++ b/src/enm/study-NWKI-a994fb96-60a5-4ad0-9cb9-c566c7f0a76e.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-a994fb96-60a5-4ad0-9cb9-c566c7f0a76e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4beee533-65e4-364a-adb7-7a520180de61"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "r_purposeFlag": null,
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+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 16
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-aa3dbdb7-90f5-43e1-9ece-29a5b0398e90.json b/src/enm/study-NWKI-aa3dbdb7-90f5-43e1-9ece-29a5b0398e90.json
new file mode 100644
index 0000000..1ea713d
--- /dev/null
+++ b/src/enm/study-NWKI-aa3dbdb7-90f5-43e1-9ece-29a5b0398e90.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-aa3dbdb7-90f5-43e1-9ece-29a5b0398e90",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-175ce512-1cbd-3a84-b216-dd0f47170dc8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "reliability": {
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+ },
+ "interpretation": {
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 16.6,
+ "errorValue": 4.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-aac134d2-3527-441c-8e37-c873b418d489.json b/src/enm/study-NWKI-aac134d2-3527-441c-8e37-c873b418d489.json
new file mode 100644
index 0000000..590d26f
--- /dev/null
+++ b/src/enm/study-NWKI-aac134d2-3527-441c-8e37-c873b418d489.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-aac134d2-3527-441c-8e37-c873b418d489",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e5b618fd-dd48-3562-9a55-737ac7a68466"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG-2DED-2DVT750"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "VT750"
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+ "ELEMENT_OR_GROUP": {
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+ "TYPE": {
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+ "result": {
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+ "textValue": "VT750"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-aacd1d5b-bbb1-4bfe-add2-1b616797b9c2.json b/src/enm/study-NWKI-aacd1d5b-bbb1-4bfe-add2-1b616797b9c2.json
new file mode 100644
index 0000000..5798795
--- /dev/null
+++ b/src/enm/study-NWKI-aacd1d5b-bbb1-4bfe-add2-1b616797b9c2.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-aacd1d5b-bbb1-4bfe-add2-1b616797b9c2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bb304faf-e44e-3103-b2a6-01b99c1c23de"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 23,
+ "upQualifier": "<=",
+ "upValue": 35
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ab95b96d-661a-4f2c-bc84-1483ee871d50.json b/src/enm/study-NWKI-ab95b96d-661a-4f2c-bc84-1483ee871d50.json
new file mode 100644
index 0000000..0c6f252
--- /dev/null
+++ b/src/enm/study-NWKI-ab95b96d-661a-4f2c-bc84-1483ee871d50.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-ab95b96d-661a-4f2c-bc84-1483ee871d50",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3d8aaa66-97d9-351b-9771-691300d5e97c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 267
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-aba213a3-9081-41d1-b925-cbcd874ee2d0.json b/src/enm/study-NWKI-aba213a3-9081-41d1-b925-cbcd874ee2d0.json
new file mode 100644
index 0000000..aaac916
--- /dev/null
+++ b/src/enm/study-NWKI-aba213a3-9081-41d1-b925-cbcd874ee2d0.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-aba213a3-9081-41d1-b925-cbcd874ee2d0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-90869553-c8fe-3ef6-8e68-47f392958127"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DCY55"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cy5.5"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cy5.5"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ac38b52d-7f93-49b6-be77-66198edb7492.json b/src/enm/study-NWKI-ac38b52d-7f93-49b6-be77-66198edb7492.json
new file mode 100644
index 0000000..1d942fb
--- /dev/null
+++ b/src/enm/study-NWKI-ac38b52d-7f93-49b6-be77-66198edb7492.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-ac38b52d-7f93-49b6-be77-66198edb7492",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5a049bb7-380d-3c89-9c39-f1310ed7b09d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 5.3,
+ "errorValue": 0.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ac5f75d2-be9e-4773-97d6-9d9219c5bb98.json b/src/enm/study-NWKI-ac5f75d2-be9e-4773-97d6-9d9219c5bb98.json
new file mode 100644
index 0000000..b00a665
--- /dev/null
+++ b/src/enm/study-NWKI-ac5f75d2-be9e-4773-97d6-9d9219c5bb98.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-ac5f75d2-be9e-4773-97d6-9d9219c5bb98",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93603a1-8e0d-372a-8acf-48533b86ecb5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 250,
+ "upQualifier": "<=",
+ "upValue": 500
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ac60ab82-10f4-454a-908b-d3d0b94a5c3c.json b/src/enm/study-NWKI-ac60ab82-10f4-454a-908b-d3d0b94a5c3c.json
new file mode 100644
index 0000000..8736b09
--- /dev/null
+++ b/src/enm/study-NWKI-ac60ab82-10f4-454a-908b-d3d0b94a5c3c.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-ac60ab82-10f4-454a-908b-d3d0b94a5c3c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-13acd41a-bbf5-362c-bb6e-54c26f4c5f73"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 71.8,
+ "errorValue": 16.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ad183e8f-53b7-4139-82f6-bbd7a4948f4e.json b/src/enm/study-NWKI-ad183e8f-53b7-4139-82f6-bbd7a4948f4e.json
new file mode 100644
index 0000000..d391614
--- /dev/null
+++ b/src/enm/study-NWKI-ad183e8f-53b7-4139-82f6-bbd7a4948f4e.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-ad183e8f-53b7-4139-82f6-bbd7a4948f4e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-82bed004-9895-3bdf-822f-0b9906d2ee06"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -7.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ad5f29a5-b5f3-4195-8acf-3e90ea113eeb.json b/src/enm/study-NWKI-ad5f29a5-b5f3-4195-8acf-3e90ea113eeb.json
new file mode 100644
index 0000000..1a6f8c0
--- /dev/null
+++ b/src/enm/study-NWKI-ad5f29a5-b5f3-4195-8acf-3e90ea113eeb.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-ad5f29a5-b5f3-4195-8acf-3e90ea113eeb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-458c2d5a-53f0-3c65-81eb-6fb5d128db59"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 6.2,
+ "errorValue": 0.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ad69fbd5-3909-4d61-9db3-4e47619b7350.json b/src/enm/study-NWKI-ad69fbd5-3909-4d61-9db3-4e47619b7350.json
new file mode 100644
index 0000000..afd40f7
--- /dev/null
+++ b/src/enm/study-NWKI-ad69fbd5-3909-4d61-9db3-4e47619b7350.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-ad69fbd5-3909-4d61-9db3-4e47619b7350",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-395bf212-b710-3385-9c23-715a7055b015"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 0
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ae01c65a-e141-4a3e-997a-07068990a1ed.json b/src/enm/study-NWKI-ae01c65a-e141-4a3e-997a-07068990a1ed.json
new file mode 100644
index 0000000..839ad21
--- /dev/null
+++ b/src/enm/study-NWKI-ae01c65a-e141-4a3e-997a-07068990a1ed.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-ae01c65a-e141-4a3e-997a-07068990a1ed",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 50,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ae4d3a55-5ea2-4964-bcc1-7f7b016aec31.json b/src/enm/study-NWKI-ae4d3a55-5ea2-4964-bcc1-7f7b016aec31.json
new file mode 100644
index 0000000..8e3eb45
--- /dev/null
+++ b/src/enm/study-NWKI-ae4d3a55-5ea2-4964-bcc1-7f7b016aec31.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-ae4d3a55-5ea2-4964-bcc1-7f7b016aec31",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-47d254de-8242-3374-9ed3-085227d473cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG-2DED-2DAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Amino_SPARK680"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Amino_SPARK680"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-af91a0ab-cd0a-4af2-9f08-5cbff02f2c02.json b/src/enm/study-NWKI-af91a0ab-cd0a-4af2-9f08-5cbff02f2c02.json
new file mode 100644
index 0000000..49230c0
--- /dev/null
+++ b/src/enm/study-NWKI-af91a0ab-cd0a-4af2-9f08-5cbff02f2c02.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-af91a0ab-cd0a-4af2-9f08-5cbff02f2c02",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-69b604fb-e892-31ba-a6f5-feb6cb04effb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
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+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 29
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-afaf9d66-7295-4597-b804-b1b6ff16380e.json b/src/enm/study-NWKI-afaf9d66-7295-4597-b804-b1b6ff16380e.json
new file mode 100644
index 0000000..c8d8cb8
--- /dev/null
+++ b/src/enm/study-NWKI-afaf9d66-7295-4597-b804-b1b6ff16380e.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-afaf9d66-7295-4597-b804-b1b6ff16380e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6821e372-3b17-3a56-8fac-f66115f24e5d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
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+ }
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+}
diff --git a/src/enm/study-NWKI-afb4950b-8b6c-49aa-bf88-002590f9da09.json b/src/enm/study-NWKI-afb4950b-8b6c-49aa-bf88-002590f9da09.json
new file mode 100644
index 0000000..a6f20ea
--- /dev/null
+++ b/src/enm/study-NWKI-afb4950b-8b6c-49aa-bf88-002590f9da09.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-afb4950b-8b6c-49aa-bf88-002590f9da09",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7efe542f-264c-3b57-a516-410b730df963"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
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+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ },
+ "result": {
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+ "loValue": 33
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+}
diff --git a/src/enm/study-NWKI-afe3c4ca-7d1a-4d30-bff9-1a803f7664ec.json b/src/enm/study-NWKI-afe3c4ca-7d1a-4d30-bff9-1a803f7664ec.json
new file mode 100644
index 0000000..43b0f81
--- /dev/null
+++ b/src/enm/study-NWKI-afe3c4ca-7d1a-4d30-bff9-1a803f7664ec.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-afe3c4ca-7d1a-4d30-bff9-1a803f7664ec",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cfea3b7c-ee39-34ef-8349-16b1e7825861"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DRhodamine-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Rhodamine"
+ },
+ "ELEMENT_OR_GROUP": {
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+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
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+ "textValue": "Rhodamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b0ec7163-0d6b-455d-ac0b-0b20289bd60a.json b/src/enm/study-NWKI-b0ec7163-0d6b-455d-ac0b-0b20289bd60a.json
new file mode 100644
index 0000000..4c9111e
--- /dev/null
+++ b/src/enm/study-NWKI-b0ec7163-0d6b-455d-ac0b-0b20289bd60a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-b0ec7163-0d6b-455d-ac0b-0b20289bd60a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c6c08b6e-cb44-3e91-9669-0979667f12b3"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1063/1.2061873",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "effects": [
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+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b163f566-9eeb-49fa-8a95-5cfcb0b308c3.json b/src/enm/study-NWKI-b163f566-9eeb-49fa-8a95-5cfcb0b308c3.json
new file mode 100644
index 0000000..e6f2535
--- /dev/null
+++ b/src/enm/study-NWKI-b163f566-9eeb-49fa-8a95-5cfcb0b308c3.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-b163f566-9eeb-49fa-8a95-5cfcb0b308c3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-21dbebfb-695f-3ff4-b7a4-bead2b52cf13"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ },
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 0.0,
+ "upQualifier": "<=",
+ "upValue": 50
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b19640e8-70fc-4f59-9673-18d993638b49.json b/src/enm/study-NWKI-b19640e8-70fc-4f59-9673-18d993638b49.json
new file mode 100644
index 0000000..a2572a8
--- /dev/null
+++ b/src/enm/study-NWKI-b19640e8-70fc-4f59-9673-18d993638b49.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-b19640e8-70fc-4f59-9673-18d993638b49",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 2000,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
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+ "loValue": 57
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b2410a3b-3566-4d20-b44d-26cc260aa5ba.json b/src/enm/study-NWKI-b2410a3b-3566-4d20-b44d-26cc260aa5ba.json
new file mode 100644
index 0000000..6d9e924
--- /dev/null
+++ b/src/enm/study-NWKI-b2410a3b-3566-4d20-b44d-26cc260aa5ba.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-b2410a3b-3566-4d20-b44d-26cc260aa5ba",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-77fb742b-c676-3ad7-bd19-6d5ec1df62ad"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
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+ "r_value": null
+ },
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+ },
+ "effects": [
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+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 60
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b253bb51-98c6-4542-ac49-1d4065642da9.json b/src/enm/study-NWKI-b253bb51-98c6-4542-ac49-1d4065642da9.json
new file mode 100644
index 0000000..cc22d62
--- /dev/null
+++ b/src/enm/study-NWKI-b253bb51-98c6-4542-ac49-1d4065642da9.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-b253bb51-98c6-4542-ac49-1d4065642da9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b8a44a2-b835-3f75-903c-cf0a71a247c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 10,
+ "unit": "m"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b2df0522-985f-4afe-b6c1-7d044f4606b9.json b/src/enm/study-NWKI-b2df0522-985f-4afe-b6c1-7d044f4606b9.json
new file mode 100644
index 0000000..e01a491
--- /dev/null
+++ b/src/enm/study-NWKI-b2df0522-985f-4afe-b6c1-7d044f4606b9.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-b2df0522-985f-4afe-b6c1-7d044f4606b9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-04962f10-34c8-3118-953e-d40d7244209c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1039/C4FD00117F",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "Å",
+ "loQualifier": ">=",
+ "loValue": 25,
+ "upQualifier": "<=",
+ "upValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b2f8f2b7-15bf-4898-86c4-ab0157786afa.json b/src/enm/study-NWKI-b2f8f2b7-15bf-4898-86c4-ab0157786afa.json
new file mode 100644
index 0000000..0164430
--- /dev/null
+++ b/src/enm/study-NWKI-b2f8f2b7-15bf-4898-86c4-ab0157786afa.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-b2f8f2b7-15bf-4898-86c4-ab0157786afa",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3db8eb74-b206-31ad-8c1b-3569703c47cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b31df475-cec5-45fb-a010-e2af8524f5bd.json b/src/enm/study-NWKI-b31df475-cec5-45fb-a010-e2af8524f5bd.json
new file mode 100644
index 0000000..11f8894
--- /dev/null
+++ b/src/enm/study-NWKI-b31df475-cec5-45fb-a010-e2af8524f5bd.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-b31df475-cec5-45fb-a010-e2af8524f5bd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-56d49cc3-4a76-354b-9a77-4b2ecb2dbef0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b3232f4d-a5ce-403b-8389-ab510c2a4fa5.json b/src/enm/study-NWKI-b3232f4d-a5ce-403b-8389-ab510c2a4fa5.json
new file mode 100644
index 0000000..e017a05
--- /dev/null
+++ b/src/enm/study-NWKI-b3232f4d-a5ce-403b-8389-ab510c2a4fa5.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-b3232f4d-a5ce-403b-8389-ab510c2a4fa5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b6c86895-1b73-39ec-8bd2-0106e77a7673"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DAF488"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b344319c-0fd1-40f5-b99d-5d63247257d2.json b/src/enm/study-NWKI-b344319c-0fd1-40f5-b99d-5d63247257d2.json
new file mode 100644
index 0000000..fd24eb6
--- /dev/null
+++ b/src/enm/study-NWKI-b344319c-0fd1-40f5-b99d-5d63247257d2.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-b344319c-0fd1-40f5-b99d-5d63247257d2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a968835-50ab-33df-bf5e-42de32d01c15"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 8
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 100
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b3e40d3a-a564-42ef-8200-bd7d9836dda1.json b/src/enm/study-NWKI-b3e40d3a-a564-42ef-8200-bd7d9836dda1.json
new file mode 100644
index 0000000..cff9e10
--- /dev/null
+++ b/src/enm/study-NWKI-b3e40d3a-a564-42ef-8200-bd7d9836dda1.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-b3e40d3a-a564-42ef-8200-bd7d9836dda1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c3d91296-7c2d-3971-b932-e671f2f83aa8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 57.4,
+ "errorValue": 16.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b415c8a0-b36e-4872-a113-e47e49172f57.json b/src/enm/study-NWKI-b415c8a0-b36e-4872-a113-e47e49172f57.json
new file mode 100644
index 0000000..ab56883
--- /dev/null
+++ b/src/enm/study-NWKI-b415c8a0-b36e-4872-a113-e47e49172f57.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-b415c8a0-b36e-4872-a113-e47e49172f57",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-db562080-5286-327a-b813-6775c437385e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DRCOOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "FITC"
+ },
+ "ELEMENT_OR_GROUP": {
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+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "FITC"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b47b3bb8-8641-4c6a-b225-19d76714e4f9.json b/src/enm/study-NWKI-b47b3bb8-8641-4c6a-b225-19d76714e4f9.json
new file mode 100644
index 0000000..79e637d
--- /dev/null
+++ b/src/enm/study-NWKI-b47b3bb8-8641-4c6a-b225-19d76714e4f9.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-b47b3bb8-8641-4c6a-b225-19d76714e4f9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-99ad0a8c-1c4b-3270-8a4b-7dab013e5fe8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 61.7,
+ "errorValue": 11.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b4ab83bc-2f09-4aee-8e13-71525a8208ac.json b/src/enm/study-NWKI-b4ab83bc-2f09-4aee-8e13-71525a8208ac.json
new file mode 100644
index 0000000..1526d44
--- /dev/null
+++ b/src/enm/study-NWKI-b4ab83bc-2f09-4aee-8e13-71525a8208ac.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-b4ab83bc-2f09-4aee-8e13-71525a8208ac",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-88767671-5631-3c93-8cfc-db0f48978e77"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.87
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b4caa096-20f9-4b80-a35a-4db2789b3d8c.json b/src/enm/study-NWKI-b4caa096-20f9-4b80-a35a-4db2789b3d8c.json
new file mode 100644
index 0000000..b550b12
--- /dev/null
+++ b/src/enm/study-NWKI-b4caa096-20f9-4b80-a35a-4db2789b3d8c.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-b4caa096-20f9-4b80-a35a-4db2789b3d8c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9a13f473-8a29-32e4-9653-ec03f5fb8923"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "AmphPolymer-2DPEG"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PEG"
+ },
+ "ELEMENT_OR_GROUP": {
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+ },
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
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+ "textValue": "PEG"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b4d22e0f-9803-4c59-8a3e-473f3c1af41b.json b/src/enm/study-NWKI-b4d22e0f-9803-4c59-8a3e-473f3c1af41b.json
new file mode 100644
index 0000000..7c41c8e
--- /dev/null
+++ b/src/enm/study-NWKI-b4d22e0f-9803-4c59-8a3e-473f3c1af41b.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-b4d22e0f-9803-4c59-8a3e-473f3c1af41b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f9f316e8-e8a9-37f9-877f-86519b3af20e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 31
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b4fed1d0-a43c-4482-8433-cd0a24220095.json b/src/enm/study-NWKI-b4fed1d0-a43c-4482-8433-cd0a24220095.json
new file mode 100644
index 0000000..4a334f4
--- /dev/null
+++ b/src/enm/study-NWKI-b4fed1d0-a43c-4482-8433-cd0a24220095.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-b4fed1d0-a43c-4482-8433-cd0a24220095",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c7bee4e3-8884-3e29-ad8b-38decf6146fd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
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+ },
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+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "FITC-2DCOOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "O=CO[H]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "COOH"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b5028307-f5a7-43ee-9f16-9056ef54bb8b.json b/src/enm/study-NWKI-b5028307-f5a7-43ee-9f16-9056ef54bb8b.json
new file mode 100644
index 0000000..3fd131e
--- /dev/null
+++ b/src/enm/study-NWKI-b5028307-f5a7-43ee-9f16-9056ef54bb8b.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-b5028307-f5a7-43ee-9f16-9056ef54bb8b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2076c0ac-9601-33fb-a221-cd3055fd9b42"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.envpol.2008.11.004",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 50
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b51e63f2-de24-4b10-838d-be0de2f1e0e1.json b/src/enm/study-NWKI-b51e63f2-de24-4b10-838d-be0de2f1e0e1.json
new file mode 100644
index 0000000..d53f7e8
--- /dev/null
+++ b/src/enm/study-NWKI-b51e63f2-de24-4b10-838d-be0de2f1e0e1.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-b51e63f2-de24-4b10-838d-be0de2f1e0e1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-395bf212-b710-3385-9c23-715a7055b015"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 80,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 0.0
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b559c4ad-cf60-4602-aab1-088948542e00.json b/src/enm/study-NWKI-b559c4ad-cf60-4602-aab1-088948542e00.json
new file mode 100644
index 0000000..ef48b59
--- /dev/null
+++ b/src/enm/study-NWKI-b559c4ad-cf60-4602-aab1-088948542e00.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-b559c4ad-cf60-4602-aab1-088948542e00",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7cbc5266-5c2e-3821-a80a-5d6a63140d83"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -48.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b5704215-4ac0-4d41-b185-53fe8b5747d7.json b/src/enm/study-NWKI-b5704215-4ac0-4d41-b185-53fe8b5747d7.json
new file mode 100644
index 0000000..9b89c76
--- /dev/null
+++ b/src/enm/study-NWKI-b5704215-4ac0-4d41-b185-53fe8b5747d7.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-b5704215-4ac0-4d41-b185-53fe8b5747d7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3424add5-867e-3dc5-864d-36c47589024b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SiO2"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "SiO2"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "APS_Coating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "APS"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "APS"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b595fad5-c9e5-42a3-902f-261561ea55c2.json b/src/enm/study-NWKI-b595fad5-c9e5-42a3-902f-261561ea55c2.json
new file mode 100644
index 0000000..df6fbac
--- /dev/null
+++ b/src/enm/study-NWKI-b595fad5-c9e5-42a3-902f-261561ea55c2.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-b595fad5-c9e5-42a3-902f-261561ea55c2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8f7f774c-d727-33a9-adc6-9068524faf1c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DCOOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b5d5c844-25e0-4df7-9855-4d18f205938b.json b/src/enm/study-NWKI-b5d5c844-25e0-4df7-9855-4d18f205938b.json
new file mode 100644
index 0000000..99fa9cd
--- /dev/null
+++ b/src/enm/study-NWKI-b5d5c844-25e0-4df7-9855-4d18f205938b.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-b5d5c844-25e0-4df7-9855-4d18f205938b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ae67096a-fca6-3afc-bade-c362e3eeadc8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 889,
+ "errorValue": 32
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b60c415e-42fc-4af0-907e-ec6d3d07aebf.json b/src/enm/study-NWKI-b60c415e-42fc-4af0-907e-ec6d3d07aebf.json
new file mode 100644
index 0000000..56fe4b4
--- /dev/null
+++ b/src/enm/study-NWKI-b60c415e-42fc-4af0-907e-ec6d3d07aebf.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-b60c415e-42fc-4af0-907e-ec6d3d07aebf",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-395bf212-b710-3385-9c23-715a7055b015"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Metabolic Activity",
+ "guideline": [
+ "Tetrazolium Salt Cleavage"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Tetrazolium Salt Cleavage"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Metabolic_Activity",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 80
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b6ad5d66-dd21-4d69-ba96-ae4e2623a8a0.json b/src/enm/study-NWKI-b6ad5d66-dd21-4d69-ba96-ae4e2623a8a0.json
new file mode 100644
index 0000000..56481ce
--- /dev/null
+++ b/src/enm/study-NWKI-b6ad5d66-dd21-4d69-ba96-ae4e2623a8a0.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-b6ad5d66-dd21-4d69-ba96-ae4e2623a8a0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c012600e-ca8e-31db-a7a8-d9f6a74e2464"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Isoelectric Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ISOELECTRIC POINT",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 6.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b6ed421d-8819-43ca-b207-0adf297e57bc.json b/src/enm/study-NWKI-b6ed421d-8819-43ca-b207-0adf297e57bc.json
new file mode 100644
index 0000000..b053096
--- /dev/null
+++ b/src/enm/study-NWKI-b6ed421d-8819-43ca-b207-0adf297e57bc.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-b6ed421d-8819-43ca-b207-0adf297e57bc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b6c86895-1b73-39ec-8bd2-0106e77a7673"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -3.34
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b6f7f4d3-684a-44c0-b32d-34be02d1b364.json b/src/enm/study-NWKI-b6f7f4d3-684a-44c0-b32d-34be02d1b364.json
new file mode 100644
index 0000000..2138ef0
--- /dev/null
+++ b/src/enm/study-NWKI-b6f7f4d3-684a-44c0-b32d-34be02d1b364.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-b6f7f4d3-684a-44c0-b32d-34be02d1b364",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a968835-50ab-33df-bf5e-42de32d01c15"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 8
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 100
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b722b764-aa2b-4c82-b3d1-3f2f29fe9b59.json b/src/enm/study-NWKI-b722b764-aa2b-4c82-b3d1-3f2f29fe9b59.json
new file mode 100644
index 0000000..9cb5690
--- /dev/null
+++ b/src/enm/study-NWKI-b722b764-aa2b-4c82-b3d1-3f2f29fe9b59.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-b722b764-aa2b-4c82-b3d1-3f2f29fe9b59",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 50,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b729c58e-a905-4e14-9074-3ee8e20d202c.json b/src/enm/study-NWKI-b729c58e-a905-4e14-9074-3ee8e20d202c.json
new file mode 100644
index 0000000..2ac5bcc
--- /dev/null
+++ b/src/enm/study-NWKI-b729c58e-a905-4e14-9074-3ee8e20d202c.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-b729c58e-a905-4e14-9074-3ee8e20d202c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-916751bb-8457-3844-87c0-ada4c6afd1ab"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "sfMEM"
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 65
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b73daa7d-227f-4a0c-b2c1-8b2515f43582.json b/src/enm/study-NWKI-b73daa7d-227f-4a0c-b2c1-8b2515f43582.json
new file mode 100644
index 0000000..35dfc64
--- /dev/null
+++ b/src/enm/study-NWKI-b73daa7d-227f-4a0c-b2c1-8b2515f43582.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-b73daa7d-227f-4a0c-b2c1-8b2515f43582",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-69fa9265-308d-30c5-9d86-1f18cde14afb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.envpol.2008.11.004",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 429
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b7848f87-76a4-4f51-a7f3-cfa1668b2670.json b/src/enm/study-NWKI-b7848f87-76a4-4f51-a7f3-cfa1668b2670.json
new file mode 100644
index 0000000..303abee
--- /dev/null
+++ b/src/enm/study-NWKI-b7848f87-76a4-4f51-a7f3-cfa1668b2670.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-b7848f87-76a4-4f51-a7f3-cfa1668b2670",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fd891814-04d2-30bc-a0b6-cc3149bf75ec"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Isoelectric Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ISOELECTRIC POINT",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 5.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b7d6c2a9-87d5-4648-b79a-872ca7706802.json b/src/enm/study-NWKI-b7d6c2a9-87d5-4648-b79a-872ca7706802.json
new file mode 100644
index 0000000..4fe3f10
--- /dev/null
+++ b/src/enm/study-NWKI-b7d6c2a9-87d5-4648-b79a-872ca7706802.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-b7d6c2a9-87d5-4648-b79a-872ca7706802",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d8f70c6c-3496-3ad3-8ab3-e4f08a178d30"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1000,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 93
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b81bcb58-126e-40d3-b4ea-3b7d613f7e1e.json b/src/enm/study-NWKI-b81bcb58-126e-40d3-b4ea-3b7d613f7e1e.json
new file mode 100644
index 0000000..1e54fdf
--- /dev/null
+++ b/src/enm/study-NWKI-b81bcb58-126e-40d3-b4ea-3b7d613f7e1e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-b81bcb58-126e-40d3-b4ea-3b7d613f7e1e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-155bb96c-2d7e-384d-b55d-45856eeda386"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b82cf2e9-5da7-4c35-8014-ecb154a3639b.json b/src/enm/study-NWKI-b82cf2e9-5da7-4c35-8014-ecb154a3639b.json
new file mode 100644
index 0000000..27e8ac7
--- /dev/null
+++ b/src/enm/study-NWKI-b82cf2e9-5da7-4c35-8014-ecb154a3639b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-b82cf2e9-5da7-4c35-8014-ecb154a3639b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-19b5dfef-0d95-3878-9075-2897e8631277"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3390/ijerph110908867",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 18,
+ "errorValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b8bdb816-6822-4cfb-b0db-d775259ada5b.json b/src/enm/study-NWKI-b8bdb816-6822-4cfb-b0db-d775259ada5b.json
new file mode 100644
index 0000000..698d80d
--- /dev/null
+++ b/src/enm/study-NWKI-b8bdb816-6822-4cfb-b0db-d775259ada5b.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-b8bdb816-6822-4cfb-b0db-d775259ada5b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7680f6c2-68d8-3ee4-b84b-8107da3f6e19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -18.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b8f2a16e-05cf-41e5-b61e-8a1be9cf8691.json b/src/enm/study-NWKI-b8f2a16e-05cf-41e5-b61e-8a1be9cf8691.json
new file mode 100644
index 0000000..2edf5da
--- /dev/null
+++ b/src/enm/study-NWKI-b8f2a16e-05cf-41e5-b61e-8a1be9cf8691.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-b8f2a16e-05cf-41e5-b61e-8a1be9cf8691",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-072b1631-f6f1-3f47-a4dc-723aa4eb0700"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Ag"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ag"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MEECoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "MEE"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SCCOCCO"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "MEE"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b92935a2-e18a-4a51-a6a8-92961b6153a7.json b/src/enm/study-NWKI-b92935a2-e18a-4a51-a6a8-92961b6153a7.json
new file mode 100644
index 0000000..c34b3ab
--- /dev/null
+++ b/src/enm/study-NWKI-b92935a2-e18a-4a51-a6a8-92961b6153a7.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-b92935a2-e18a-4a51-a6a8-92961b6153a7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d42892b8-9b57-30a2-aa89-af61880c337a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -0.877
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b9477bfc-dc2b-4ea2-aee9-528395dfeeee.json b/src/enm/study-NWKI-b9477bfc-dc2b-4ea2-aee9-528395dfeeee.json
new file mode 100644
index 0000000..1174f3a
--- /dev/null
+++ b/src/enm/study-NWKI-b9477bfc-dc2b-4ea2-aee9-528395dfeeee.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-b9477bfc-dc2b-4ea2-aee9-528395dfeeee",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d7e38d71-0fcb-3a23-8cbe-aae4ce82b33a"
+ },
+ "company": {
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+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
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+ }
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+}
diff --git a/src/enm/study-NWKI-b9676734-2d7d-4cf5-85ea-4002591b618a.json b/src/enm/study-NWKI-b9676734-2d7d-4cf5-85ea-4002591b618a.json
new file mode 100644
index 0000000..5f5b6fb
--- /dev/null
+++ b/src/enm/study-NWKI-b9676734-2d7d-4cf5-85ea-4002591b618a.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-b9676734-2d7d-4cf5-85ea-4002591b618a",
+ "owner": {
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+ "uuid": "NWKI-5172b34a-a6f6-398f-ace6-1d30e6bc9efa"
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+ "name": "NanoWiki"
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+ "year": "0",
+ "owner": "NanoWiki"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
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+ },
+ "result": {
+ "unit": null,
+ "textValue": "NH2"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b97b0b06-7f24-4f70-8b99-fa7db4806950.json b/src/enm/study-NWKI-b97b0b06-7f24-4f70-8b99-fa7db4806950.json
new file mode 100644
index 0000000..20dfc41
--- /dev/null
+++ b/src/enm/study-NWKI-b97b0b06-7f24-4f70-8b99-fa7db4806950.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-b97b0b06-7f24-4f70-8b99-fa7db4806950",
+ "owner": {
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+ "name": "NanoWiki"
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+ },
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+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
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+ ]
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+ "ELEMENT_OR_GROUP": {
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+ "loValue": "Fe3O4"
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+ "Remark": null,
+ "TYPE": {
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+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "loValue": "CLIO-2DCY35-2DTat"
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+ "DESCRIPTION": {
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+ "TYPE": {
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+ "textValue": "Cross-2Dlinked_dextran"
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+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b9a32c67-76d3-431b-b2a4-aa4dabc27537.json b/src/enm/study-NWKI-b9a32c67-76d3-431b-b2a4-aa4dabc27537.json
new file mode 100644
index 0000000..d761458
--- /dev/null
+++ b/src/enm/study-NWKI-b9a32c67-76d3-431b-b2a4-aa4dabc27537.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-b9a32c67-76d3-431b-b2a4-aa4dabc27537",
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1016/j.envpol.2008.11.004",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+ "TESTMAT_FORM": null
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+ ]
+}
diff --git a/src/enm/study-NWKI-b9e19cf2-74b1-4293-a8ed-9dfc47833398.json b/src/enm/study-NWKI-b9e19cf2-74b1-4293-a8ed-9dfc47833398.json
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index 0000000..fa472f8
--- /dev/null
+++ b/src/enm/study-NWKI-b9e19cf2-74b1-4293-a8ed-9dfc47833398.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-b9e19cf2-74b1-4293-a8ed-9dfc47833398",
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+ "year": "0",
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+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+ "DISTRIBUTION_TYPE": null,
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+ },
+ "result": {
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+ "loValue": 27
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-b9ed5cb5-983c-4c0a-af8f-7af2afb81e7d.json b/src/enm/study-NWKI-b9ed5cb5-983c-4c0a-af8f-7af2afb81e7d.json
new file mode 100644
index 0000000..5d1bc83
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+++ b/src/enm/study-NWKI-b9ed5cb5-983c-4c0a-af8f-7af2afb81e7d.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-b9ed5cb5-983c-4c0a-af8f-7af2afb81e7d",
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+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 10,
+ "unit": "m"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ba3469fb-e14c-482e-8b8a-8d84e92c02ea.json b/src/enm/study-NWKI-ba3469fb-e14c-482e-8b8a-8d84e92c02ea.json
new file mode 100644
index 0000000..f70d25a
--- /dev/null
+++ b/src/enm/study-NWKI-ba3469fb-e14c-482e-8b8a-8d84e92c02ea.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-ba3469fb-e14c-482e-8b8a-8d84e92c02ea",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b5385309-1812-33ad-a4cf-66d8d3a26bcc"
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+ "name": "NanoWiki"
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+ },
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+ "year": "0",
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+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ },
+ "result": {
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+ "loValue": 14.2,
+ "errorValue": 1.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bb1d9e70-67eb-4f36-af0d-1e150743f576.json b/src/enm/study-NWKI-bb1d9e70-67eb-4f36-af0d-1e150743f576.json
new file mode 100644
index 0000000..94bad46
--- /dev/null
+++ b/src/enm/study-NWKI-bb1d9e70-67eb-4f36-af0d-1e150743f576.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-bb1d9e70-67eb-4f36-af0d-1e150743f576",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d8f70c6c-3496-3ad3-8ab3-e4f08a178d30"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "unit": "mg/L"
+ }
+ },
+ "result": {
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+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bb3415eb-1dba-4325-baff-417320e89afb.json b/src/enm/study-NWKI-bb3415eb-1dba-4325-baff-417320e89afb.json
new file mode 100644
index 0000000..b215c24
--- /dev/null
+++ b/src/enm/study-NWKI-bb3415eb-1dba-4325-baff-417320e89afb.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-bb3415eb-1dba-4325-baff-417320e89afb",
+ "owner": {
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+ "uuid": "NWKI-202b322d-51c9-3d73-a049-1e4019f8ddad"
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+ "company": {
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+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ },
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diff --git a/src/enm/study-NWKI-bb3b0f78-9209-45ee-8a5d-03c0342b1fa7.json b/src/enm/study-NWKI-bb3b0f78-9209-45ee-8a5d-03c0342b1fa7.json
new file mode 100644
index 0000000..ee6ceaa
--- /dev/null
+++ b/src/enm/study-NWKI-bb3b0f78-9209-45ee-8a5d-03c0342b1fa7.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-bb3b0f78-9209-45ee-8a5d-03c0342b1fa7",
+ "owner": {
+ "substance": {
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+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1039/C4FD00117F",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+ "loQualifier": ">=",
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+ ]
+}
diff --git a/src/enm/study-NWKI-bc0e2bcb-b5f0-4b5e-b0a0-f5151c353825.json b/src/enm/study-NWKI-bc0e2bcb-b5f0-4b5e-b0a0-f5151c353825.json
new file mode 100644
index 0000000..4f1b1b0
--- /dev/null
+++ b/src/enm/study-NWKI-bc0e2bcb-b5f0-4b5e-b0a0-f5151c353825.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-bc0e2bcb-b5f0-4b5e-b0a0-f5151c353825",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e866549e-38cf-3b98-a0b1-a483e275d261"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "Shape",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Gamma phase"
+ },
+ "effects": [
+ {
+ "endpoint": "SHAPE",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Gamma phase"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bc3086e8-cb66-4c29-9f6e-156525fad6d1.json b/src/enm/study-NWKI-bc3086e8-cb66-4c29-9f6e-156525fad6d1.json
new file mode 100644
index 0000000..c1417fd
--- /dev/null
+++ b/src/enm/study-NWKI-bc3086e8-cb66-4c29-9f6e-156525fad6d1.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-bc3086e8-cb66-4c29-9f6e-156525fad6d1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 250,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bc3de50b-f2a1-42c1-b4b5-a180e292b177.json b/src/enm/study-NWKI-bc3de50b-f2a1-42c1-b4b5-a180e292b177.json
new file mode 100644
index 0000000..d557947
--- /dev/null
+++ b/src/enm/study-NWKI-bc3de50b-f2a1-42c1-b4b5-a180e292b177.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-bc3de50b-f2a1-42c1-b4b5-a180e292b177",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-db562080-5286-327a-b813-6775c437385e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -10.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bc486e1b-f68b-4911-a4af-990994e8fd72.json b/src/enm/study-NWKI-bc486e1b-f68b-4911-a4af-990994e8fd72.json
new file mode 100644
index 0000000..d5c4843
--- /dev/null
+++ b/src/enm/study-NWKI-bc486e1b-f68b-4911-a4af-990994e8fd72.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-bc486e1b-f68b-4911-a4af-990994e8fd72",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bcf835c5-7b6d-4dd4-99a9-318d9b5b4e90.json b/src/enm/study-NWKI-bcf835c5-7b6d-4dd4-99a9-318d9b5b4e90.json
new file mode 100644
index 0000000..30e5d1f
--- /dev/null
+++ b/src/enm/study-NWKI-bcf835c5-7b6d-4dd4-99a9-318d9b5b4e90.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-bcf835c5-7b6d-4dd4-99a9-318d9b5b4e90",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3db8eb74-b206-31ad-8c1b-3569703c47cb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 109.8,
+ "errorValue": 34.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bd297302-a9f6-4bc6-ab88-1ba058356fd3.json b/src/enm/study-NWKI-bd297302-a9f6-4bc6-ab88-1ba058356fd3.json
new file mode 100644
index 0000000..963e531
--- /dev/null
+++ b/src/enm/study-NWKI-bd297302-a9f6-4bc6-ab88-1ba058356fd3.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-bd297302-a9f6-4bc6-ab88-1ba058356fd3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4b4cb369-8202-3483-9220-553e433c9159"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 31
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bd4d124b-86d8-4a04-ba5a-cb9e28ddf28a.json b/src/enm/study-NWKI-bd4d124b-86d8-4a04-ba5a-cb9e28ddf28a.json
new file mode 100644
index 0000000..c613621
--- /dev/null
+++ b/src/enm/study-NWKI-bd4d124b-86d8-4a04-ba5a-cb9e28ddf28a.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-bd4d124b-86d8-4a04-ba5a-cb9e28ddf28a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9142c528-4a84-3566-b678-dc1eef7d22fe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 60
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-be9f2ae3-be0e-402f-a6ba-5aada4c4c956.json b/src/enm/study-NWKI-be9f2ae3-be0e-402f-a6ba-5aada4c4c956.json
new file mode 100644
index 0000000..a71c286
--- /dev/null
+++ b/src/enm/study-NWKI-be9f2ae3-be0e-402f-a6ba-5aada4c4c956.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-be9f2ae3-be0e-402f-a6ba-5aada4c4c956",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cad5bf58-cc90-33e5-88bb-bad4c9f9fe9e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DCY5"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cy5"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cy5"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bf2c9635-9a3d-4781-bca7-3c1f86ea0cba.json b/src/enm/study-NWKI-bf2c9635-9a3d-4781-bca7-3c1f86ea0cba.json
new file mode 100644
index 0000000..24c9abe
--- /dev/null
+++ b/src/enm/study-NWKI-bf2c9635-9a3d-4781-bca7-3c1f86ea0cba.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-bf2c9635-9a3d-4781-bca7-3c1f86ea0cba",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-37a99dad-2a53-3076-b21f-d078b89fb4fb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 7
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 12,
+ "errorValue": 2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bf93fd51-2b80-4693-9538-e973ec01fdd2.json b/src/enm/study-NWKI-bf93fd51-2b80-4693-9538-e973ec01fdd2.json
new file mode 100644
index 0000000..bf76743
--- /dev/null
+++ b/src/enm/study-NWKI-bf93fd51-2b80-4693-9538-e973ec01fdd2.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-bf93fd51-2b80-4693-9538-e973ec01fdd2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a968835-50ab-33df-bf5e-42de32d01c15"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 102
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-bfe29db1-dc25-4f4d-8f01-2dc81a86c3ed.json b/src/enm/study-NWKI-bfe29db1-dc25-4f4d-8f01-2dc81a86c3ed.json
new file mode 100644
index 0000000..aadd8e4
--- /dev/null
+++ b/src/enm/study-NWKI-bfe29db1-dc25-4f4d-8f01-2dc81a86c3ed.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-bfe29db1-dc25-4f4d-8f01-2dc81a86c3ed",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 102
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c00c3206-3fd1-4ed3-a9f7-4b1374927387.json b/src/enm/study-NWKI-c00c3206-3fd1-4ed3-a9f7-4b1374927387.json
new file mode 100644
index 0000000..95471cf
--- /dev/null
+++ b/src/enm/study-NWKI-c00c3206-3fd1-4ed3-a9f7-4b1374927387.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c00c3206-3fd1-4ed3-a9f7-4b1374927387",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-438d1468-d5d7-3977-9dab-15a3a05add38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c0ad98c0-9298-490c-ae70-a1a9a015d197.json b/src/enm/study-NWKI-c0ad98c0-9298-490c-ae70-a1a9a015d197.json
new file mode 100644
index 0000000..dd4d0a6
--- /dev/null
+++ b/src/enm/study-NWKI-c0ad98c0-9298-490c-ae70-a1a9a015d197.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-c0ad98c0-9298-490c-ae70-a1a9a015d197",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e0386856-5e55-330a-9b5e-364c00de2f2b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12.3,
+ "errorValue": 2.9
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c0b96f94-f4be-4ef2-8626-e84110817c99.json b/src/enm/study-NWKI-c0b96f94-f4be-4ef2-8626-e84110817c99.json
new file mode 100644
index 0000000..f0c0f04
--- /dev/null
+++ b/src/enm/study-NWKI-c0b96f94-f4be-4ef2-8626-e84110817c99.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-c0b96f94-f4be-4ef2-8626-e84110817c99",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8f7f774c-d727-33a9-adc6-9068524faf1c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DCOOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "O=CO[H]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "COOH"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c0c037fe-f4fb-4abc-9969-0dc3e4006d91.json b/src/enm/study-NWKI-c0c037fe-f4fb-4abc-9969-0dc3e4006d91.json
new file mode 100644
index 0000000..88332db
--- /dev/null
+++ b/src/enm/study-NWKI-c0c037fe-f4fb-4abc-9969-0dc3e4006d91.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-c0c037fe-f4fb-4abc-9969-0dc3e4006d91",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5ae4ae3d-db28-3647-9a7a-0c2e3d8076aa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 60
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c0ef8f7c-d2d0-4048-ac36-008db15fd81c.json b/src/enm/study-NWKI-c0ef8f7c-d2d0-4048-ac36-008db15fd81c.json
new file mode 100644
index 0000000..d4ff1ed
--- /dev/null
+++ b/src/enm/study-NWKI-c0ef8f7c-d2d0-4048-ac36-008db15fd81c.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-c0ef8f7c-d2d0-4048-ac36-008db15fd81c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-895a506b-c331-3576-bf9e-cbcde5822c11"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "cMEM"
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 81
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c1234f21-498a-475e-872e-24a5202362ab.json b/src/enm/study-NWKI-c1234f21-498a-475e-872e-24a5202362ab.json
new file mode 100644
index 0000000..5c8b25b
--- /dev/null
+++ b/src/enm/study-NWKI-c1234f21-498a-475e-872e-24a5202362ab.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c1234f21-498a-475e-872e-24a5202362ab",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c1478b66-7fc6-4181-ad1e-cb95b0d84dca.json b/src/enm/study-NWKI-c1478b66-7fc6-4181-ad1e-cb95b0d84dca.json
new file mode 100644
index 0000000..ec3e28d
--- /dev/null
+++ b/src/enm/study-NWKI-c1478b66-7fc6-4181-ad1e-cb95b0d84dca.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-c1478b66-7fc6-4181-ad1e-cb95b0d84dca",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b110d018-6de0-303b-afcc-6a5e1f5911aa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 132
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c15e1b66-8c5c-4c14-bc32-cc68e87e3ca1.json b/src/enm/study-NWKI-c15e1b66-8c5c-4c14-bc32-cc68e87e3ca1.json
new file mode 100644
index 0000000..0db759a
--- /dev/null
+++ b/src/enm/study-NWKI-c15e1b66-8c5c-4c14-bc32-cc68e87e3ca1.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c15e1b66-8c5c-4c14-bc32-cc68e87e3ca1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c186d7c2-0f51-4d53-969d-56fe3692dc68.json b/src/enm/study-NWKI-c186d7c2-0f51-4d53-969d-56fe3692dc68.json
new file mode 100644
index 0000000..3bb83fe
--- /dev/null
+++ b/src/enm/study-NWKI-c186d7c2-0f51-4d53-969d-56fe3692dc68.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c186d7c2-0f51-4d53-969d-56fe3692dc68",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9fb12a3a-3a26-3f95-82ed-371f58d92dfe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 173,
+ "errorValue": 17
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c1ae6c51-2308-42fd-90c7-a73c8acb6fdc.json b/src/enm/study-NWKI-c1ae6c51-2308-42fd-90c7-a73c8acb6fdc.json
new file mode 100644
index 0000000..5ec5c79
--- /dev/null
+++ b/src/enm/study-NWKI-c1ae6c51-2308-42fd-90c7-a73c8acb6fdc.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c1ae6c51-2308-42fd-90c7-a73c8acb6fdc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 200,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c1bb1427-0626-4b72-896e-ab772919fce2.json b/src/enm/study-NWKI-c1bb1427-0626-4b72-896e-ab772919fce2.json
new file mode 100644
index 0000000..64cb638
--- /dev/null
+++ b/src/enm/study-NWKI-c1bb1427-0626-4b72-896e-ab772919fce2.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-c1bb1427-0626-4b72-896e-ab772919fce2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bbb67d89-eaff-38ab-ba4f-403bfb064a0c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DED-2DSuccAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Ethylene_Diamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "NCCN"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ethylene_Diamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c215b9a1-98b2-4937-8747-aec9b78f4ef4.json b/src/enm/study-NWKI-c215b9a1-98b2-4937-8747-aec9b78f4ef4.json
new file mode 100644
index 0000000..559560f
--- /dev/null
+++ b/src/enm/study-NWKI-c215b9a1-98b2-4937-8747-aec9b78f4ef4.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-c215b9a1-98b2-4937-8747-aec9b78f4ef4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2a046d54-ea47-31b2-a370-e886e5a0a6bb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "BiotinCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c2463846-6b9a-4c71-a4b3-dedea84d7645.json b/src/enm/study-NWKI-c2463846-6b9a-4c71-a4b3-dedea84d7645.json
new file mode 100644
index 0000000..2409d39
--- /dev/null
+++ b/src/enm/study-NWKI-c2463846-6b9a-4c71-a4b3-dedea84d7645.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c2463846-6b9a-4c71-a4b3-dedea84d7645",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 5,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c27eb7d0-84da-440c-a01a-4f42f78e80fe.json b/src/enm/study-NWKI-c27eb7d0-84da-440c-a01a-4f42f78e80fe.json
new file mode 100644
index 0000000..59df3f1
--- /dev/null
+++ b/src/enm/study-NWKI-c27eb7d0-84da-440c-a01a-4f42f78e80fe.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c27eb7d0-84da-440c-a01a-4f42f78e80fe",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0a6e319e-71fc-37f7-b88d-fbda2e07ccc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 2000,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 88
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c2f5256d-cedb-47c6-9caf-8dc827cf445f.json b/src/enm/study-NWKI-c2f5256d-cedb-47c6-9caf-8dc827cf445f.json
new file mode 100644
index 0000000..fd4aaf5
--- /dev/null
+++ b/src/enm/study-NWKI-c2f5256d-cedb-47c6-9caf-8dc827cf445f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c2f5256d-cedb-47c6-9caf-8dc827cf445f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-395bf212-b710-3385-9c23-715a7055b015"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "BET",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 300
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c327ffa8-dbc1-4ce7-813d-d595b6d2eba8.json b/src/enm/study-NWKI-c327ffa8-dbc1-4ce7-813d-d595b6d2eba8.json
new file mode 100644
index 0000000..0e59a9b
--- /dev/null
+++ b/src/enm/study-NWKI-c327ffa8-dbc1-4ce7-813d-d595b6d2eba8.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c327ffa8-dbc1-4ce7-813d-d595b6d2eba8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6.25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c333c3a5-ccab-4104-af6d-dc079e051b30.json b/src/enm/study-NWKI-c333c3a5-ccab-4104-af6d-dc079e051b30.json
new file mode 100644
index 0000000..6744ecb
--- /dev/null
+++ b/src/enm/study-NWKI-c333c3a5-ccab-4104-af6d-dc079e051b30.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-c333c3a5-ccab-4104-af6d-dc079e051b30",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ad44f58f-8080-3017-9f8d-485fad044849"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DRhodamine-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Rhodamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Rhodamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c363d3ac-5a15-4fb4-a84c-c04fc482857a.json b/src/enm/study-NWKI-c363d3ac-5a15-4fb4-a84c-c04fc482857a.json
new file mode 100644
index 0000000..8206e28
--- /dev/null
+++ b/src/enm/study-NWKI-c363d3ac-5a15-4fb4-a84c-c04fc482857a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-c363d3ac-5a15-4fb4-a84c-c04fc482857a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-666817c2-87cb-3826-92f8-e79a7b37957d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 67
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c42bcc42-46a4-4f5a-8ada-254aa78f8c67.json b/src/enm/study-NWKI-c42bcc42-46a4-4f5a-8ada-254aa78f8c67.json
new file mode 100644
index 0000000..8847669
--- /dev/null
+++ b/src/enm/study-NWKI-c42bcc42-46a4-4f5a-8ada-254aa78f8c67.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c42bcc42-46a4-4f5a-8ada-254aa78f8c67",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c4a6e3f7-9b6d-4a08-9a7b-2371e6d964d7.json b/src/enm/study-NWKI-c4a6e3f7-9b6d-4a08-9a7b-2371e6d964d7.json
new file mode 100644
index 0000000..e51d487
--- /dev/null
+++ b/src/enm/study-NWKI-c4a6e3f7-9b6d-4a08-9a7b-2371e6d964d7.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-c4a6e3f7-9b6d-4a08-9a7b-2371e6d964d7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bbb67d89-eaff-38ab-ba4f-403bfb064a0c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -12.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c4ab521d-9cd7-4933-b4aa-e881f92846a8.json b/src/enm/study-NWKI-c4ab521d-9cd7-4933-b4aa-e881f92846a8.json
new file mode 100644
index 0000000..ca639b9
--- /dev/null
+++ b/src/enm/study-NWKI-c4ab521d-9cd7-4933-b4aa-e881f92846a8.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-c4ab521d-9cd7-4933-b4aa-e881f92846a8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a32cb420-7aa2-3130-9612-edfe833d83fc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
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+ "Method details": null,
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+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 25
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c4b706f3-7240-4d55-9642-56dbc3083ce6.json b/src/enm/study-NWKI-c4b706f3-7240-4d55-9642-56dbc3083ce6.json
new file mode 100644
index 0000000..1fda38b
--- /dev/null
+++ b/src/enm/study-NWKI-c4b706f3-7240-4d55-9642-56dbc3083ce6.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c4b706f3-7240-4d55-9642-56dbc3083ce6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cc55dabc-3794-3853-9cf1-1e0bcf31fb69"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 27.2,
+ "errorValue": 3.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c4d59b68-76c2-4d23-85af-6b8a34e09c6e.json b/src/enm/study-NWKI-c4d59b68-76c2-4d23-85af-6b8a34e09c6e.json
new file mode 100644
index 0000000..70c8a00
--- /dev/null
+++ b/src/enm/study-NWKI-c4d59b68-76c2-4d23-85af-6b8a34e09c6e.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c4d59b68-76c2-4d23-85af-6b8a34e09c6e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c4fd9f71-f95f-4a63-b75b-0e545eeb6199.json b/src/enm/study-NWKI-c4fd9f71-f95f-4a63-b75b-0e545eeb6199.json
new file mode 100644
index 0000000..248bb9d
--- /dev/null
+++ b/src/enm/study-NWKI-c4fd9f71-f95f-4a63-b75b-0e545eeb6199.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-c4fd9f71-f95f-4a63-b75b-0e545eeb6199",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4e021275-ae4e-3d24-bdb8-40c6d8d9d6fc"
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+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
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+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ "Remark": null,
+ "pH": null
+ },
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+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c54c86ac-49f3-4655-9faf-4055521df1e8.json b/src/enm/study-NWKI-c54c86ac-49f3-4655-9faf-4055521df1e8.json
new file mode 100644
index 0000000..8c9efc2
--- /dev/null
+++ b/src/enm/study-NWKI-c54c86ac-49f3-4655-9faf-4055521df1e8.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-c54c86ac-49f3-4655-9faf-4055521df1e8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c3ff049e-e72a-35fe-9bbf-77f018259d63"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "BET",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
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+ },
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+ },
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+ "effects": [
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+ "loQualifier": ">=",
+ "loValue": 0.0,
+ "upQualifier": "<=",
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c55f2582-d7a3-4263-aac5-8b336397ca1c.json b/src/enm/study-NWKI-c55f2582-d7a3-4263-aac5-8b336397ca1c.json
new file mode 100644
index 0000000..05a9dd3
--- /dev/null
+++ b/src/enm/study-NWKI-c55f2582-d7a3-4263-aac5-8b336397ca1c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c55f2582-d7a3-4263-aac5-8b336397ca1c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f6f54a71-9459-397b-b0f7-b27538cff042"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
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+ "year": "0",
+ "owner": "NanoWiki"
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+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
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+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 306,
+ "errorValue": 42
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c572805a-4c79-4717-8365-b8f801d9901a.json b/src/enm/study-NWKI-c572805a-4c79-4717-8365-b8f801d9901a.json
new file mode 100644
index 0000000..007dd12
--- /dev/null
+++ b/src/enm/study-NWKI-c572805a-4c79-4717-8365-b8f801d9901a.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-c572805a-4c79-4717-8365-b8f801d9901a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5172b34a-a6f6-398f-ace6-1d30e6bc9efa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
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+ ]
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+ "TESTMAT_FORM": null
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+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c5820914-4974-473c-84f0-7795422f6ae2.json b/src/enm/study-NWKI-c5820914-4974-473c-84f0-7795422f6ae2.json
new file mode 100644
index 0000000..d476323
--- /dev/null
+++ b/src/enm/study-NWKI-c5820914-4974-473c-84f0-7795422f6ae2.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-c5820914-4974-473c-84f0-7795422f6ae2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-82c12809-d7af-3061-a531-1db744c521f0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
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+ },
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+ },
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+ "endpoint": "ATOMIC COMPOSITION",
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
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+ "Remark": null,
+ "TYPE": {
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+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c62b9663-f3c5-446d-9096-d7cd0c27a11f.json b/src/enm/study-NWKI-c62b9663-f3c5-446d-9096-d7cd0c27a11f.json
new file mode 100644
index 0000000..ea1abe5
--- /dev/null
+++ b/src/enm/study-NWKI-c62b9663-f3c5-446d-9096-d7cd0c27a11f.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-c62b9663-f3c5-446d-9096-d7cd0c27a11f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9f37da26-8619-3eb1-9c29-e5f9ea09de54"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "effects": [
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+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 64,
+ "errorValue": 1.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c645880a-bdc5-42fe-acc0-6952484b5edb.json b/src/enm/study-NWKI-c645880a-bdc5-42fe-acc0-6952484b5edb.json
new file mode 100644
index 0000000..937ed87
--- /dev/null
+++ b/src/enm/study-NWKI-c645880a-bdc5-42fe-acc0-6952484b5edb.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-c645880a-bdc5-42fe-acc0-6952484b5edb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-369d200e-2bfc-392d-ae00-ceb41fabd459"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn200546k",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 1.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c65ca657-472d-4e5b-a8ad-ca5d8b33d057.json b/src/enm/study-NWKI-c65ca657-472d-4e5b-a8ad-ca5d8b33d057.json
new file mode 100644
index 0000000..ec3b920
--- /dev/null
+++ b/src/enm/study-NWKI-c65ca657-472d-4e5b-a8ad-ca5d8b33d057.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-c65ca657-472d-4e5b-a8ad-ca5d8b33d057",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c8d9772c-e50e-3c71-986c-e45692150d71"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ "r_isUsedforClassification": "false",
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+ "r_value": null
+ },
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+ "ELEMENT_OR_GROUP": {
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+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "COATING_DESCRIPTION": {
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+ "loValue": "PVA-2DCOOH"
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+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "O=CO[H]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
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+ "result": {
+ "unit": null,
+ "textValue": "COOH"
+ }
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+ ]
+}
diff --git a/src/enm/study-NWKI-c6ca1bd3-e533-4859-92a8-d494ba6b7a08.json b/src/enm/study-NWKI-c6ca1bd3-e533-4859-92a8-d494ba6b7a08.json
new file mode 100644
index 0000000..8178033
--- /dev/null
+++ b/src/enm/study-NWKI-c6ca1bd3-e533-4859-92a8-d494ba6b7a08.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-c6ca1bd3-e533-4859-92a8-d494ba6b7a08",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ef8660fd-e624-3a94-91bc-ad5a6e47bcf3"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "SAMPLING": null,
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+ "endpoint": "ATOMIC COMPOSITION",
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+ "textValue": "Fe3O4"
+ }
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+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "COATING_DESCRIPTION": {
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+ "loValue": "Arabino_Galactan"
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+ "ELEMENT_OR_GROUP": {
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Arabino_Galactan"
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+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c6fe8e37-e6f1-44d8-8a80-99c26d6b73ca.json b/src/enm/study-NWKI-c6fe8e37-e6f1-44d8-8a80-99c26d6b73ca.json
new file mode 100644
index 0000000..9122964
--- /dev/null
+++ b/src/enm/study-NWKI-c6fe8e37-e6f1-44d8-8a80-99c26d6b73ca.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-c6fe8e37-e6f1-44d8-8a80-99c26d6b73ca",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-82bed004-9895-3bdf-822f-0b9906d2ee06"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
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+ "interpretation": {
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+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DDArg7COOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "D-2DArginine-2D7-2DCOOH"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
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+ }
+ },
+ "result": {
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+ "textValue": "D-2DArginine-2D7-2DCOOH"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c74426f1-d3f0-47f1-9dab-39c735b1d5db.json b/src/enm/study-NWKI-c74426f1-d3f0-47f1-9dab-39c735b1d5db.json
new file mode 100644
index 0000000..a718c87
--- /dev/null
+++ b/src/enm/study-NWKI-c74426f1-d3f0-47f1-9dab-39c735b1d5db.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-c74426f1-d3f0-47f1-9dab-39c735b1d5db",
+ "owner": {
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+ "name": "NanoWiki"
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+ "citation": {
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+ "year": "0",
+ "owner": "NanoWiki"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c7865053-f199-4816-9f79-de2f3d849b70.json b/src/enm/study-NWKI-c7865053-f199-4816-9f79-de2f3d849b70.json
new file mode 100644
index 0000000..0c3ef69
--- /dev/null
+++ b/src/enm/study-NWKI-c7865053-f199-4816-9f79-de2f3d849b70.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-c7865053-f199-4816-9f79-de2f3d849b70",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d3c8fab1-762e-32b8-a46e-cf4158f8ec49"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "SEQ_NUM": null
+ },
+ "result": {
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+ "loValue": 70
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c7a4a433-7264-40b6-8aaf-20f0c90e5fa4.json b/src/enm/study-NWKI-c7a4a433-7264-40b6-8aaf-20f0c90e5fa4.json
new file mode 100644
index 0000000..1b9d747
--- /dev/null
+++ b/src/enm/study-NWKI-c7a4a433-7264-40b6-8aaf-20f0c90e5fa4.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-c7a4a433-7264-40b6-8aaf-20f0c90e5fa4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cc55dabc-3794-3853-9cf1-1e0bcf31fb69"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "Remark": null,
+ "pH": null
+ },
+ "result": {
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+ "loValue": -58
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c7a9d6f8-0d62-4aa7-b9e4-611475a74e48.json b/src/enm/study-NWKI-c7a9d6f8-0d62-4aa7-b9e4-611475a74e48.json
new file mode 100644
index 0000000..70f71be
--- /dev/null
+++ b/src/enm/study-NWKI-c7a9d6f8-0d62-4aa7-b9e4-611475a74e48.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-c7a9d6f8-0d62-4aa7-b9e4-611475a74e48",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-438d1468-d5d7-3977-9dab-15a3a05add38"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c7ab52cf-dcbf-4b3a-b246-25604905b5c6.json b/src/enm/study-NWKI-c7ab52cf-dcbf-4b3a-b246-25604905b5c6.json
new file mode 100644
index 0000000..9668dd8
--- /dev/null
+++ b/src/enm/study-NWKI-c7ab52cf-dcbf-4b3a-b246-25604905b5c6.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-c7ab52cf-dcbf-4b3a-b246-25604905b5c6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-afc33b0f-f6ce-3c1b-8a3d-cede13515323"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c7f84ccb-8474-4b7c-8674-aa196eac6741.json b/src/enm/study-NWKI-c7f84ccb-8474-4b7c-8674-aa196eac6741.json
new file mode 100644
index 0000000..5dabca5
--- /dev/null
+++ b/src/enm/study-NWKI-c7f84ccb-8474-4b7c-8674-aa196eac6741.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-c7f84ccb-8474-4b7c-8674-aa196eac6741",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3b09fdd1-3024-3be3-b1c6-332b44f75f99"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c8075a01-07fe-4205-b282-e58f993175ab.json b/src/enm/study-NWKI-c8075a01-07fe-4205-b282-e58f993175ab.json
new file mode 100644
index 0000000..30a1e03
--- /dev/null
+++ b/src/enm/study-NWKI-c8075a01-07fe-4205-b282-e58f993175ab.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c8075a01-07fe-4205-b282-e58f993175ab",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 200,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-c8207d31-f8f9-48db-ba39-15668b625d56.json b/src/enm/study-NWKI-c8207d31-f8f9-48db-ba39-15668b625d56.json
new file mode 100644
index 0000000..cbc8c02
--- /dev/null
+++ b/src/enm/study-NWKI-c8207d31-f8f9-48db-ba39-15668b625d56.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-c8207d31-f8f9-48db-ba39-15668b625d56",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5f88a526-3e3f-3da5-8082-8d1da0cdfefa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
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+ "title": "4.5 Particle size distribution (Granulometry)"
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new file mode 100644
index 0000000..58d38c8
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+++ b/src/enm/study-NWKI-c84603a4-4444-4b84-b8e8-c7f3ca1c0bf0.json
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+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
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+ "endpoint": "Particle Size",
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new file mode 100644
index 0000000..ed4cb96
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+++ b/src/enm/study-NWKI-c864edd3-9ac3-4f4a-bbd6-ba8038476061.json
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+{
+ "uuid": "NWKI-c864edd3-9ac3-4f4a-bbd6-ba8038476061",
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
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diff --git a/src/enm/study-NWKI-c8c7a34c-83af-4fe7-a02c-0a417ab17eea.json b/src/enm/study-NWKI-c8c7a34c-83af-4fe7-a02c-0a417ab17eea.json
new file mode 100644
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+++ b/src/enm/study-NWKI-c8c7a34c-83af-4fe7-a02c-0a417ab17eea.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-c8c7a34c-83af-4fe7-a02c-0a417ab17eea",
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+ "owner": "NanoWiki"
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+ "category": {
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+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
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+ ""
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diff --git a/src/enm/study-NWKI-c8d35a03-2511-4004-a35b-70ca09de5d0c.json b/src/enm/study-NWKI-c8d35a03-2511-4004-a35b-70ca09de5d0c.json
new file mode 100644
index 0000000..bea2fcf
--- /dev/null
+++ b/src/enm/study-NWKI-c8d35a03-2511-4004-a35b-70ca09de5d0c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-c8d35a03-2511-4004-a35b-70ca09de5d0c",
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+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
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+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
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+ "Cell line": "HaCaT",
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+ "unit": "mg/L"
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+ "loValue": 74.3
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index 0000000..972e935
--- /dev/null
+++ b/src/enm/study-NWKI-c8f1ee43-48b3-4305-b131-8bd700da8beb.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-c8f1ee43-48b3-4305-b131-8bd700da8beb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
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+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
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+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
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+ },
+ "Incubation Time": {
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+ }
+ },
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+ "loValue": 90
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+ ]
+}
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new file mode 100644
index 0000000..f5c86e4
--- /dev/null
+++ b/src/enm/study-NWKI-c8fbf5fb-579e-4848-9157-f0ab7864a30d.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-c8fbf5fb-579e-4848-9157-f0ab7864a30d",
+ "owner": {
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
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diff --git a/src/enm/study-NWKI-c9a98eea-c9b4-485b-891f-e715ffbe4792.json b/src/enm/study-NWKI-c9a98eea-c9b4-485b-891f-e715ffbe4792.json
new file mode 100644
index 0000000..23b718e
--- /dev/null
+++ b/src/enm/study-NWKI-c9a98eea-c9b4-485b-891f-e715ffbe4792.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-c9a98eea-c9b4-485b-891f-e715ffbe4792",
+ "owner": {
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+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
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+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
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diff --git a/src/enm/study-NWKI-c9b7dc82-8a66-49fb-8374-769b7beb12d5.json b/src/enm/study-NWKI-c9b7dc82-8a66-49fb-8374-769b7beb12d5.json
new file mode 100644
index 0000000..d8508f0
--- /dev/null
+++ b/src/enm/study-NWKI-c9b7dc82-8a66-49fb-8374-769b7beb12d5.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-c9b7dc82-8a66-49fb-8374-769b7beb12d5",
+ "owner": {
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+ "name": "NanoWiki"
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+ "owner": "NanoWiki"
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+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
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+ ""
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+ "textValue": "PVA"
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diff --git a/src/enm/study-NWKI-ca3d7a1a-7879-4241-b1da-bdf2fba9e10f.json b/src/enm/study-NWKI-ca3d7a1a-7879-4241-b1da-bdf2fba9e10f.json
new file mode 100644
index 0000000..f0807b2
--- /dev/null
+++ b/src/enm/study-NWKI-ca3d7a1a-7879-4241-b1da-bdf2fba9e10f.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-ca3d7a1a-7879-4241-b1da-bdf2fba9e10f",
+ "owner": {
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+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
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+ ""
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+ ]
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diff --git a/src/enm/study-NWKI-ca5604bc-2495-46fd-9dd5-9a6ad63058f6.json b/src/enm/study-NWKI-ca5604bc-2495-46fd-9dd5-9a6ad63058f6.json
new file mode 100644
index 0000000..6f0a982
--- /dev/null
+++ b/src/enm/study-NWKI-ca5604bc-2495-46fd-9dd5-9a6ad63058f6.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-ca5604bc-2495-46fd-9dd5-9a6ad63058f6",
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
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+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ca95fac8-a830-415a-8228-5640a8690cba.json b/src/enm/study-NWKI-ca95fac8-a830-415a-8228-5640a8690cba.json
new file mode 100644
index 0000000..dd0f0db
--- /dev/null
+++ b/src/enm/study-NWKI-ca95fac8-a830-415a-8228-5640a8690cba.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-ca95fac8-a830-415a-8228-5640a8690cba",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-984a9c7f-2372-3b8f-9ff5-93a9f94f2eb7"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -13.2,
+ "errorValue": 1.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cac867ed-e155-4f41-b9d5-1f5d0b4fe602.json b/src/enm/study-NWKI-cac867ed-e155-4f41-b9d5-1f5d0b4fe602.json
new file mode 100644
index 0000000..39f220f
--- /dev/null
+++ b/src/enm/study-NWKI-cac867ed-e155-4f41-b9d5-1f5d0b4fe602.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-cac867ed-e155-4f41-b9d5-1f5d0b4fe602",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 200,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cae065a9-5659-4188-a9f1-c0992c8f9148.json b/src/enm/study-NWKI-cae065a9-5659-4188-a9f1-c0992c8f9148.json
new file mode 100644
index 0000000..6e20d3f
--- /dev/null
+++ b/src/enm/study-NWKI-cae065a9-5659-4188-a9f1-c0992c8f9148.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-cae065a9-5659-4188-a9f1-c0992c8f9148",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e6ef5597-a3f9-3f21-afff-db5f654ef534"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
+ "upValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cb2fb3aa-2d41-467d-897a-48c64f399e43.json b/src/enm/study-NWKI-cb2fb3aa-2d41-467d-897a-48c64f399e43.json
new file mode 100644
index 0000000..51ce754
--- /dev/null
+++ b/src/enm/study-NWKI-cb2fb3aa-2d41-467d-897a-48c64f399e43.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-cb2fb3aa-2d41-467d-897a-48c64f399e43",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 8
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cb6f500d-8d1c-4196-94b8-1a8b9bcd30f6.json b/src/enm/study-NWKI-cb6f500d-8d1c-4196-94b8-1a8b9bcd30f6.json
new file mode 100644
index 0000000..e72a4ec
--- /dev/null
+++ b/src/enm/study-NWKI-cb6f500d-8d1c-4196-94b8-1a8b9bcd30f6.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-cb6f500d-8d1c-4196-94b8-1a8b9bcd30f6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-41e63d70-d7c0-3bd2-9a65-e99dcdedb1a5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -51.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cc5b881d-450b-46a0-acf0-0b59464a24f8.json b/src/enm/study-NWKI-cc5b881d-450b-46a0-acf0-0b59464a24f8.json
new file mode 100644
index 0000000..be600a7
--- /dev/null
+++ b/src/enm/study-NWKI-cc5b881d-450b-46a0-acf0-0b59464a24f8.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-cc5b881d-450b-46a0-acf0-0b59464a24f8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7998492c-3902-3cc2-9f92-cdfae53cfc02"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 3,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cd054b32-9679-4de6-9770-3e0b6935bd20.json b/src/enm/study-NWKI-cd054b32-9679-4de6-9770-3e0b6935bd20.json
new file mode 100644
index 0000000..da53f89
--- /dev/null
+++ b/src/enm/study-NWKI-cd054b32-9679-4de6-9770-3e0b6935bd20.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-cd054b32-9679-4de6-9770-3e0b6935bd20",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b14e37d1-8dbb-36d7-925c-4093c91a0e92"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cd0f4a3a-377f-456a-b142-1f5d7726f318.json b/src/enm/study-NWKI-cd0f4a3a-377f-456a-b142-1f5d7726f318.json
new file mode 100644
index 0000000..f5afc15
--- /dev/null
+++ b/src/enm/study-NWKI-cd0f4a3a-377f-456a-b142-1f5d7726f318.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-cd0f4a3a-377f-456a-b142-1f5d7726f318",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-666817c2-87cb-3826-92f8-e79a7b37957d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cd4bbc5e-2a02-47f5-be5c-c2cb8d013a8b.json b/src/enm/study-NWKI-cd4bbc5e-2a02-47f5-be5c-c2cb8d013a8b.json
new file mode 100644
index 0000000..711faee
--- /dev/null
+++ b/src/enm/study-NWKI-cd4bbc5e-2a02-47f5-be5c-c2cb8d013a8b.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-cd4bbc5e-2a02-47f5-be5c-c2cb8d013a8b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cddd50dd-d01f-41e3-8223-bf8bb3f790d9.json b/src/enm/study-NWKI-cddd50dd-d01f-41e3-8223-bf8bb3f790d9.json
new file mode 100644
index 0000000..963ad90
--- /dev/null
+++ b/src/enm/study-NWKI-cddd50dd-d01f-41e3-8223-bf8bb3f790d9.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-cddd50dd-d01f-41e3-8223-bf8bb3f790d9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-18aebb90-aacb-3e15-b516-4d3683e9c27b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 40,
+ "upQualifier": "<=",
+ "upValue": 300
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ce2bfbe2-1161-4c0e-ba26-281cd1f4c497.json b/src/enm/study-NWKI-ce2bfbe2-1161-4c0e-ba26-281cd1f4c497.json
new file mode 100644
index 0000000..9b2555a
--- /dev/null
+++ b/src/enm/study-NWKI-ce2bfbe2-1161-4c0e-ba26-281cd1f4c497.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-ce2bfbe2-1161-4c0e-ba26-281cd1f4c497",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cfea3b7c-ee39-34ef-8349-16b1e7825861"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 0.25
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ce2e0558-33d9-4205-bf48-b1f053a73a96.json b/src/enm/study-NWKI-ce2e0558-33d9-4205-bf48-b1f053a73a96.json
new file mode 100644
index 0000000..481f5bc
--- /dev/null
+++ b/src/enm/study-NWKI-ce2e0558-33d9-4205-bf48-b1f053a73a96.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-ce2e0558-33d9-4205-bf48-b1f053a73a96",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e373781b-461e-35dd-ae27-4169b7d743af"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "FITC"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "FITC"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ce622deb-7190-4284-a5e1-eee219c4d6b0.json b/src/enm/study-NWKI-ce622deb-7190-4284-a5e1-eee219c4d6b0.json
new file mode 100644
index 0000000..74ae839
--- /dev/null
+++ b/src/enm/study-NWKI-ce622deb-7190-4284-a5e1-eee219c4d6b0.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-ce622deb-7190-4284-a5e1-eee219c4d6b0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-895a506b-c331-3576-bf9e-cbcde5822c11"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "Serum": {
+ "loValue": "PBS"
+ },
+ "pH": {
+ "loValue": 7.45
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -36
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ce6412b4-8280-4c33-8930-d44cf9813219.json b/src/enm/study-NWKI-ce6412b4-8280-4c33-8930-d44cf9813219.json
new file mode 100644
index 0000000..91955de
--- /dev/null
+++ b/src/enm/study-NWKI-ce6412b4-8280-4c33-8930-d44cf9813219.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-ce6412b4-8280-4c33-8930-d44cf9813219",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93a9eb3-83df-3522-b417-7b3a379054a6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 280
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ce73ec54-2cbf-4476-add4-d2ad07ccc89f.json b/src/enm/study-NWKI-ce73ec54-2cbf-4476-add4-d2ad07ccc89f.json
new file mode 100644
index 0000000..7e7a773
--- /dev/null
+++ b/src/enm/study-NWKI-ce73ec54-2cbf-4476-add4-d2ad07ccc89f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-ce73ec54-2cbf-4476-add4-d2ad07ccc89f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ce97c205-4d65-4d45-8c55-00427a250663.json b/src/enm/study-NWKI-ce97c205-4d65-4d45-8c55-00427a250663.json
new file mode 100644
index 0000000..ecb3486
--- /dev/null
+++ b/src/enm/study-NWKI-ce97c205-4d65-4d45-8c55-00427a250663.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-ce97c205-4d65-4d45-8c55-00427a250663",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2581f636-c16f-3680-9b3a-2bf0c8cab0b1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -54.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cf25b134-5092-45c7-b48f-807252da6799.json b/src/enm/study-NWKI-cf25b134-5092-45c7-b48f-807252da6799.json
new file mode 100644
index 0000000..c067ed9
--- /dev/null
+++ b/src/enm/study-NWKI-cf25b134-5092-45c7-b48f-807252da6799.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-cf25b134-5092-45c7-b48f-807252da6799",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-33eda014-7b69-358a-93f0-e0ceef166a52"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "conditions": {
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+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -39.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cf2e640c-3ae5-4149-bd89-81fe25149e93.json b/src/enm/study-NWKI-cf2e640c-3ae5-4149-bd89-81fe25149e93.json
new file mode 100644
index 0000000..3d47bf2
--- /dev/null
+++ b/src/enm/study-NWKI-cf2e640c-3ae5-4149-bd89-81fe25149e93.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-cf2e640c-3ae5-4149-bd89-81fe25149e93",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b1b44fa-70c1-3034-9c4b-7efb334762e0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cf538ea0-cd50-4731-88f6-fccfee1145ad.json b/src/enm/study-NWKI-cf538ea0-cd50-4731-88f6-fccfee1145ad.json
new file mode 100644
index 0000000..e1646bf
--- /dev/null
+++ b/src/enm/study-NWKI-cf538ea0-cd50-4731-88f6-fccfee1145ad.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-cf538ea0-cd50-4731-88f6-fccfee1145ad",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9f37da26-8619-3eb1-9c29-e5f9ea09de54"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 221,
+ "errorValue": 0.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cf70e3af-ea76-4f8d-87cf-e51296a88be4.json b/src/enm/study-NWKI-cf70e3af-ea76-4f8d-87cf-e51296a88be4.json
new file mode 100644
index 0000000..38562b8
--- /dev/null
+++ b/src/enm/study-NWKI-cf70e3af-ea76-4f8d-87cf-e51296a88be4.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-cf70e3af-ea76-4f8d-87cf-e51296a88be4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3d8aaa66-97d9-351b-9771-691300d5e97c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-cfd7a3eb-b360-4bac-9b3e-16b4698b9103.json b/src/enm/study-NWKI-cfd7a3eb-b360-4bac-9b3e-16b4698b9103.json
new file mode 100644
index 0000000..8f54c49
--- /dev/null
+++ b/src/enm/study-NWKI-cfd7a3eb-b360-4bac-9b3e-16b4698b9103.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-cfd7a3eb-b360-4bac-9b3e-16b4698b9103",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cc55dabc-3794-3853-9cf1-1e0bcf31fb69"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "SiO2"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "SiO2"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH_Coating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "COOH"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "O=CO[H]"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "COOH"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d01537d1-37be-4bd6-904e-f63663b50e3f.json b/src/enm/study-NWKI-d01537d1-37be-4bd6-904e-f63663b50e3f.json
new file mode 100644
index 0000000..6fea173
--- /dev/null
+++ b/src/enm/study-NWKI-d01537d1-37be-4bd6-904e-f63663b50e3f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-d01537d1-37be-4bd6-904e-f63663b50e3f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-1af17b5b-947a-3fd2-a000-cadf542dea4d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 116,
+ "errorValue": 26
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d03c4839-a764-49e5-9117-f1f25c396c3e.json b/src/enm/study-NWKI-d03c4839-a764-49e5-9117-f1f25c396c3e.json
new file mode 100644
index 0000000..06b3699
--- /dev/null
+++ b/src/enm/study-NWKI-d03c4839-a764-49e5-9117-f1f25c396c3e.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-d03c4839-a764-49e5-9117-f1f25c396c3e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 45
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d09421ea-de27-446c-8dd4-c475e3a51de7.json b/src/enm/study-NWKI-d09421ea-de27-446c-8dd4-c475e3a51de7.json
new file mode 100644
index 0000000..034d299
--- /dev/null
+++ b/src/enm/study-NWKI-d09421ea-de27-446c-8dd4-c475e3a51de7.json
@@ -0,0 +1,93 @@
+{
+ "uuid": "NWKI-d09421ea-de27-446c-8dd4-c475e3a51de7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e5b618fd-dd48-3562-9a55-737ac7a68466"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG-2DED-2DVT750"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Ethylene_Diamine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "NCCN"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Ethylene_Diamine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d09c69c6-09df-4b84-952f-ba478fa185fd.json b/src/enm/study-NWKI-d09c69c6-09df-4b84-952f-ba478fa185fd.json
new file mode 100644
index 0000000..32be288
--- /dev/null
+++ b/src/enm/study-NWKI-d09c69c6-09df-4b84-952f-ba478fa185fd.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-d09c69c6-09df-4b84-952f-ba478fa185fd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e0ffe4e6-978c-367d-a011-bd700587c9fe"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d17c12f1-7406-4114-82b4-2e1bc70fb96f.json b/src/enm/study-NWKI-d17c12f1-7406-4114-82b4-2e1bc70fb96f.json
new file mode 100644
index 0000000..2d49af7
--- /dev/null
+++ b/src/enm/study-NWKI-d17c12f1-7406-4114-82b4-2e1bc70fb96f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-d17c12f1-7406-4114-82b4-2e1bc70fb96f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-666817c2-87cb-3826-92f8-e79a7b37957d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 60
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d19e51b2-561d-460c-8614-c85e7e887e92.json b/src/enm/study-NWKI-d19e51b2-561d-460c-8614-c85e7e887e92.json
new file mode 100644
index 0000000..337d2a5
--- /dev/null
+++ b/src/enm/study-NWKI-d19e51b2-561d-460c-8614-c85e7e887e92.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-d19e51b2-561d-460c-8614-c85e7e887e92",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a4b3e23-3327-3421-b20a-2e71939b44b1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DGlutamicAcid"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d1eaef56-d795-4c70-8af6-5c4da695891e.json b/src/enm/study-NWKI-d1eaef56-d795-4c70-8af6-5c4da695891e.json
new file mode 100644
index 0000000..69831cf
--- /dev/null
+++ b/src/enm/study-NWKI-d1eaef56-d795-4c70-8af6-5c4da695891e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-d1eaef56-d795-4c70-8af6-5c4da695891e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f1cc0abb-2905-3699-be62-b238a21e6bad"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 0.0,
+ "upQualifier": "<=",
+ "upValue": 50
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d21a01d9-18f0-4c76-ac87-ce5792d8a1f6.json b/src/enm/study-NWKI-d21a01d9-18f0-4c76-ac87-ce5792d8a1f6.json
new file mode 100644
index 0000000..939a7f5
--- /dev/null
+++ b/src/enm/study-NWKI-d21a01d9-18f0-4c76-ac87-ce5792d8a1f6.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-d21a01d9-18f0-4c76-ac87-ce5792d8a1f6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d24f4f01-e311-4e37-a276-ee42155aa89f.json b/src/enm/study-NWKI-d24f4f01-e311-4e37-a276-ee42155aa89f.json
new file mode 100644
index 0000000..18cdcad
--- /dev/null
+++ b/src/enm/study-NWKI-d24f4f01-e311-4e37-a276-ee42155aa89f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-d24f4f01-e311-4e37-a276-ee42155aa89f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d32092e6-7b57-448b-b8d1-2c6b2eaf9e28.json b/src/enm/study-NWKI-d32092e6-7b57-448b-b8d1-2c6b2eaf9e28.json
new file mode 100644
index 0000000..1889acd
--- /dev/null
+++ b/src/enm/study-NWKI-d32092e6-7b57-448b-b8d1-2c6b2eaf9e28.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-d32092e6-7b57-448b-b8d1-2c6b2eaf9e28",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4832de65-5a92-3849-8061-729a2d83017e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 38
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d363ac4e-29fd-4673-9b2a-5dfc42af0fbc.json b/src/enm/study-NWKI-d363ac4e-29fd-4673-9b2a-5dfc42af0fbc.json
new file mode 100644
index 0000000..e46b0b5
--- /dev/null
+++ b/src/enm/study-NWKI-d363ac4e-29fd-4673-9b2a-5dfc42af0fbc.json
@@ -0,0 +1,54 @@
+{
+ "uuid": "NWKI-d363ac4e-29fd-4673-9b2a-5dfc42af0fbc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2af8ed34-029d-3644-8327-23a596cfae0d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_BOILING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000257",
+ "title": "4.3 Boiling point"
+ },
+ "endpoint": "Boiling Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Boiling point",
+ "conditions": {
+ "Atm. Pressure": null,
+ "Decomposition": null
+ },
+ "result": {
+ "unit": "°C",
+ "loValue": 2230
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d37b40f8-aadf-497e-b6f0-13a752fc4839.json b/src/enm/study-NWKI-d37b40f8-aadf-497e-b6f0-13a752fc4839.json
new file mode 100644
index 0000000..8240bd9
--- /dev/null
+++ b/src/enm/study-NWKI-d37b40f8-aadf-497e-b6f0-13a752fc4839.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-d37b40f8-aadf-497e-b6f0-13a752fc4839",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-82bed004-9895-3bdf-822f-0b9906d2ee06"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d3946e40-9b64-499d-9782-b80aaeba64d0.json b/src/enm/study-NWKI-d3946e40-9b64-499d-9782-b80aaeba64d0.json
new file mode 100644
index 0000000..c8fa752
--- /dev/null
+++ b/src/enm/study-NWKI-d3946e40-9b64-499d-9782-b80aaeba64d0.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-d3946e40-9b64-499d-9782-b80aaeba64d0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 0
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d4333b24-64e1-448c-8b0a-880633a58698.json b/src/enm/study-NWKI-d4333b24-64e1-448c-8b0a-880633a58698.json
new file mode 100644
index 0000000..c79c708
--- /dev/null
+++ b/src/enm/study-NWKI-d4333b24-64e1-448c-8b0a-880633a58698.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-d4333b24-64e1-448c-8b0a-880633a58698",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f9f316e8-e8a9-37f9-877f-86519b3af20e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DFITC-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d47eb16a-4a2e-4b2e-9dde-a413623cd2e1.json b/src/enm/study-NWKI-d47eb16a-4a2e-4b2e-9dde-a413623cd2e1.json
new file mode 100644
index 0000000..5f5a5e8
--- /dev/null
+++ b/src/enm/study-NWKI-d47eb16a-4a2e-4b2e-9dde-a413623cd2e1.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-d47eb16a-4a2e-4b2e-9dde-a413623cd2e1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d4e7916c-9c3c-439c-96e6-e7fde7d866a2.json b/src/enm/study-NWKI-d4e7916c-9c3c-439c-96e6-e7fde7d866a2.json
new file mode 100644
index 0000000..a8aef54
--- /dev/null
+++ b/src/enm/study-NWKI-d4e7916c-9c3c-439c-96e6-e7fde7d866a2.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-d4e7916c-9c3c-439c-96e6-e7fde7d866a2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-61515bd0-5a80-3428-a093-01be1d677862"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 23.1,
+ "errorValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d4f7c4f3-c00a-4572-a2fa-5f174ec7d412.json b/src/enm/study-NWKI-d4f7c4f3-c00a-4572-a2fa-5f174ec7d412.json
new file mode 100644
index 0000000..0f01f76
--- /dev/null
+++ b/src/enm/study-NWKI-d4f7c4f3-c00a-4572-a2fa-5f174ec7d412.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-d4f7c4f3-c00a-4572-a2fa-5f174ec7d412",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c05becdf-4b9b-3599-9922-89235b2e10da"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -37
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d51a019b-52b5-4263-98aa-a3f9535c9db8.json b/src/enm/study-NWKI-d51a019b-52b5-4263-98aa-a3f9535c9db8.json
new file mode 100644
index 0000000..1cc6157
--- /dev/null
+++ b/src/enm/study-NWKI-d51a019b-52b5-4263-98aa-a3f9535c9db8.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-d51a019b-52b5-4263-98aa-a3f9535c9db8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0a6e319e-71fc-37f7-b88d-fbda2e07ccc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1000,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 92
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d55980e2-2f36-417f-8243-9eb758f57dd3.json b/src/enm/study-NWKI-d55980e2-2f36-417f-8243-9eb758f57dd3.json
new file mode 100644
index 0000000..f5c7575
--- /dev/null
+++ b/src/enm/study-NWKI-d55980e2-2f36-417f-8243-9eb758f57dd3.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-d55980e2-2f36-417f-8243-9eb758f57dd3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 50,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d59c481d-eb03-4319-8994-a0e250e3edfe.json b/src/enm/study-NWKI-d59c481d-eb03-4319-8994-a0e250e3edfe.json
new file mode 100644
index 0000000..1b11723
--- /dev/null
+++ b/src/enm/study-NWKI-d59c481d-eb03-4319-8994-a0e250e3edfe.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-d59c481d-eb03-4319-8994-a0e250e3edfe",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9f46a2dd-dda3-3c99-81c0-8d904172c345"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -73.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d5b02413-e80f-4df6-baa6-1da0cc43ef92.json b/src/enm/study-NWKI-d5b02413-e80f-4df6-baa6-1da0cc43ef92.json
new file mode 100644
index 0000000..299fc2f
--- /dev/null
+++ b/src/enm/study-NWKI-d5b02413-e80f-4df6-baa6-1da0cc43ef92.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-d5b02413-e80f-4df6-baa6-1da0cc43ef92",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97a6970a-0e83-3890-ae6e-5e83b99c0325"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
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+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+}
diff --git a/src/enm/study-NWKI-d5b501c9-3b68-4aaa-ab10-597a10525c6b.json b/src/enm/study-NWKI-d5b501c9-3b68-4aaa-ab10-597a10525c6b.json
new file mode 100644
index 0000000..f0c3ca9
--- /dev/null
+++ b/src/enm/study-NWKI-d5b501c9-3b68-4aaa-ab10-597a10525c6b.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-d5b501c9-3b68-4aaa-ab10-597a10525c6b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2a046d54-ea47-31b2-a370-e886e5a0a6bb"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
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+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ },
+ "interpretation": {
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+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "loValue": "BiotinCoating"
+ },
+ "DESCRIPTION": {
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+ },
+ "ELEMENT_OR_GROUP": {
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+ "textValue": "FITC"
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+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d5e6f259-f334-47d7-882b-339469b2d6c7.json b/src/enm/study-NWKI-d5e6f259-f334-47d7-882b-339469b2d6c7.json
new file mode 100644
index 0000000..6d2e6ca
--- /dev/null
+++ b/src/enm/study-NWKI-d5e6f259-f334-47d7-882b-339469b2d6c7.json
@@ -0,0 +1,55 @@
+{
+ "uuid": "NWKI-d5e6f259-f334-47d7-882b-339469b2d6c7",
+ "owner": {
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+ "year": "0",
+ "owner": "NanoWiki"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_MELTING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000256",
+ "title": "4.2 Melting point / freezing point"
+ },
+ "endpoint": "Melting Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "reliability": {
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+ "endpoint": "Melting Point",
+ "conditions": {
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+ "Sublimation": null
+ },
+ "result": {
+ "unit": "°C",
+ "loQualifier": ">=",
+ "loValue": 1600
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d6228eb8-afa7-438c-92b2-d9b264aee538.json b/src/enm/study-NWKI-d6228eb8-afa7-438c-92b2-d9b264aee538.json
new file mode 100644
index 0000000..fcab7a7
--- /dev/null
+++ b/src/enm/study-NWKI-d6228eb8-afa7-438c-92b2-d9b264aee538.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-d6228eb8-afa7-438c-92b2-d9b264aee538",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a40c7554-4bd8-3938-82a9-bf9db1f7bc13"
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+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
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+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ },
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+ },
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+ },
+ "effects": [
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+ "pH": {
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+ }
+ },
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+ "loValue": -45.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d6634dea-1f89-439a-b8e2-14039dea0262.json b/src/enm/study-NWKI-d6634dea-1f89-439a-b8e2-14039dea0262.json
new file mode 100644
index 0000000..6e01994
--- /dev/null
+++ b/src/enm/study-NWKI-d6634dea-1f89-439a-b8e2-14039dea0262.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-d6634dea-1f89-439a-b8e2-14039dea0262",
+ "owner": {
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+ "uuid": "NWKI-ea2bb63b-fd2a-32c2-a41a-d0280abaf29f"
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+ "name": "NanoWiki"
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ },
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+ "loQualifier": ">=",
+ "loValue": 15,
+ "upQualifier": "<=",
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+ }
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+ ]
+}
diff --git a/src/enm/study-NWKI-d67ffc65-30bd-4fa7-8a1a-c2f9560de597.json b/src/enm/study-NWKI-d67ffc65-30bd-4fa7-8a1a-c2f9560de597.json
new file mode 100644
index 0000000..31da2d2
--- /dev/null
+++ b/src/enm/study-NWKI-d67ffc65-30bd-4fa7-8a1a-c2f9560de597.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-d67ffc65-30bd-4fa7-8a1a-c2f9560de597",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3d8aaa66-97d9-351b-9771-691300d5e97c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "Shape",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Anatase"
+ },
+ "effects": [
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+ "endpoint": "SHAPE",
+ "conditions": {
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+ },
+ "result": {
+ "unit": null,
+ "textValue": "Anatase"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d7937308-6dab-41ce-a8fc-7752c77293a2.json b/src/enm/study-NWKI-d7937308-6dab-41ce-a8fc-7752c77293a2.json
new file mode 100644
index 0000000..f146d6a
--- /dev/null
+++ b/src/enm/study-NWKI-d7937308-6dab-41ce-a8fc-7752c77293a2.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-d7937308-6dab-41ce-a8fc-7752c77293a2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5ae4ae3d-db28-3647-9a7a-0c2e3d8076aa"
+ },
+ "company": {
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+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
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+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "pH": null
+ },
+ "result": {
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+ "loValue": -6.05
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+ ]
+}
diff --git a/src/enm/study-NWKI-d7aafa0b-c408-44e1-b288-9a479cb3dca1.json b/src/enm/study-NWKI-d7aafa0b-c408-44e1-b288-9a479cb3dca1.json
new file mode 100644
index 0000000..67738f0
--- /dev/null
+++ b/src/enm/study-NWKI-d7aafa0b-c408-44e1-b288-9a479cb3dca1.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-d7aafa0b-c408-44e1-b288-9a479cb3dca1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5e5ed57f-33d3-39bb-9511-3604a0babf5e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn2021056",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "loValue": 12,
+ "errorValue": 2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d80cd93a-4e4b-4957-a555-d6ef17f06b1b.json b/src/enm/study-NWKI-d80cd93a-4e4b-4957-a555-d6ef17f06b1b.json
new file mode 100644
index 0000000..febdd08
--- /dev/null
+++ b/src/enm/study-NWKI-d80cd93a-4e4b-4957-a555-d6ef17f06b1b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-d80cd93a-4e4b-4957-a555-d6ef17f06b1b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1000,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 70
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d8375116-28d0-4f57-84f8-91fe10910712.json b/src/enm/study-NWKI-d8375116-28d0-4f57-84f8-91fe10910712.json
new file mode 100644
index 0000000..d37ce18
--- /dev/null
+++ b/src/enm/study-NWKI-d8375116-28d0-4f57-84f8-91fe10910712.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-d8375116-28d0-4f57-84f8-91fe10910712",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c93a144a-cd6d-3fe0-ab86-13adb168ccb1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_MELTING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000256",
+ "title": "4.2 Melting point / freezing point"
+ },
+ "endpoint": "Melting Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "result": {
+ "unit": "Celsius"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d8519fb8-dff7-4317-82e5-cdf3c99eeea8.json b/src/enm/study-NWKI-d8519fb8-dff7-4317-82e5-cdf3c99eeea8.json
new file mode 100644
index 0000000..060b909
--- /dev/null
+++ b/src/enm/study-NWKI-d8519fb8-dff7-4317-82e5-cdf3c99eeea8.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-d8519fb8-dff7-4317-82e5-cdf3c99eeea8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6cde234d-f073-3e1d-acd2-0ea10a01763f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "pH": {
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+ },
+ "result": {
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+ "loValue": -44.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d86e6d2d-7cb2-4b9d-b196-3d6188634cc1.json b/src/enm/study-NWKI-d86e6d2d-7cb2-4b9d-b196-3d6188634cc1.json
new file mode 100644
index 0000000..2c1dd2e
--- /dev/null
+++ b/src/enm/study-NWKI-d86e6d2d-7cb2-4b9d-b196-3d6188634cc1.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-d86e6d2d-7cb2-4b9d-b196-3d6188634cc1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-758c06ae-dc1f-3cbe-a409-91d14e5113d1"
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+ "title": "4.30 Nanomaterial surface chemistry"
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+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "loValue": "VT750"
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+ }
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+}
diff --git a/src/enm/study-NWKI-d88abc39-2ed8-4835-ad25-b23982c9ad4a.json b/src/enm/study-NWKI-d88abc39-2ed8-4835-ad25-b23982c9ad4a.json
new file mode 100644
index 0000000..a123273
--- /dev/null
+++ b/src/enm/study-NWKI-d88abc39-2ed8-4835-ad25-b23982c9ad4a.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-d88abc39-2ed8-4835-ad25-b23982c9ad4a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-08b685e5-70fa-39b5-87ad-092df4a60568"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "MEDIUM": null,
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+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -56.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d9006c65-1eec-4cc1-b274-1738400627ff.json b/src/enm/study-NWKI-d9006c65-1eec-4cc1-b274-1738400627ff.json
new file mode 100644
index 0000000..d391ef1
--- /dev/null
+++ b/src/enm/study-NWKI-d9006c65-1eec-4cc1-b274-1738400627ff.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-d9006c65-1eec-4cc1-b274-1738400627ff",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-1c2fcc25-c597-3fab-b383-fb203ef4a69a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ },
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 9.48,
+ "errorValue": 1.26
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d9b323b6-cc7b-4d29-a03b-aad51389d92b.json b/src/enm/study-NWKI-d9b323b6-cc7b-4d29-a03b-aad51389d92b.json
new file mode 100644
index 0000000..1470390
--- /dev/null
+++ b/src/enm/study-NWKI-d9b323b6-cc7b-4d29-a03b-aad51389d92b.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-d9b323b6-cc7b-4d29-a03b-aad51389d92b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-47d254de-8242-3374-9ed3-085227d473cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG-2DED-2DAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "ED"
+ },
+ "ELEMENT_OR_GROUP": {
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+ },
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+ "TYPE": {
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+ "loValue": "COATING"
+ }
+ },
+ "result": {
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+ "textValue": "ED"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d9c32176-7528-4879-8bc4-930c8e965db1.json b/src/enm/study-NWKI-d9c32176-7528-4879-8bc4-930c8e965db1.json
new file mode 100644
index 0000000..e145651
--- /dev/null
+++ b/src/enm/study-NWKI-d9c32176-7528-4879-8bc4-930c8e965db1.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-d9c32176-7528-4879-8bc4-930c8e965db1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5454d5cb-1033-3d6f-a31e-038752525533"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 200
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d9cdbe0d-05e6-4d3b-8c05-1f957e5b317e.json b/src/enm/study-NWKI-d9cdbe0d-05e6-4d3b-8c05-1f957e5b317e.json
new file mode 100644
index 0000000..8ee8ba2
--- /dev/null
+++ b/src/enm/study-NWKI-d9cdbe0d-05e6-4d3b-8c05-1f957e5b317e.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-d9cdbe0d-05e6-4d3b-8c05-1f957e5b317e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8196e92b-c46d-3c14-9410-e87992810710"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ },
+ "reliability": {
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "loValue": "ED-2DPVA"
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+ "DESCRIPTION": {
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+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
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+ "TYPE": {
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+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-d9f7009b-c7da-4a61-b3d8-7d475465a081.json b/src/enm/study-NWKI-d9f7009b-c7da-4a61-b3d8-7d475465a081.json
new file mode 100644
index 0000000..447892e
--- /dev/null
+++ b/src/enm/study-NWKI-d9f7009b-c7da-4a61-b3d8-7d475465a081.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-d9f7009b-c7da-4a61-b3d8-7d475465a081",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9a41ca03-303d-3116-89fb-2335cc1bad2d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Diameter",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 11
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-da0a27f7-bbfd-4f1f-a3a1-10d6a5994c9b.json b/src/enm/study-NWKI-da0a27f7-bbfd-4f1f-a3a1-10d6a5994c9b.json
new file mode 100644
index 0000000..97f0241
--- /dev/null
+++ b/src/enm/study-NWKI-da0a27f7-bbfd-4f1f-a3a1-10d6a5994c9b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-da0a27f7-bbfd-4f1f-a3a1-10d6a5994c9b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9f37da26-8619-3eb1-9c29-e5f9ea09de54"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-da126db9-3a18-4d18-8c38-71486a8dac52.json b/src/enm/study-NWKI-da126db9-3a18-4d18-8c38-71486a8dac52.json
new file mode 100644
index 0000000..ecd5a0b
--- /dev/null
+++ b/src/enm/study-NWKI-da126db9-3a18-4d18-8c38-71486a8dac52.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-da126db9-3a18-4d18-8c38-71486a8dac52",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-1c2fcc25-c597-3fab-b383-fb203ef4a69a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
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+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
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+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 46.7,
+ "errorValue": 6.28
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-da94bc66-2353-4c5b-b79a-394b815a1032.json b/src/enm/study-NWKI-da94bc66-2353-4c5b-b79a-394b815a1032.json
new file mode 100644
index 0000000..a692557
--- /dev/null
+++ b/src/enm/study-NWKI-da94bc66-2353-4c5b-b79a-394b815a1032.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-da94bc66-2353-4c5b-b79a-394b815a1032",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-80364e0e-be06-3645-a3ae-880ae0edddef"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "effects": [
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+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 119,
+ "errorValue": 16
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-daba0539-9011-4d0a-90d4-556ebd9d1a46.json b/src/enm/study-NWKI-daba0539-9011-4d0a-90d4-556ebd9d1a46.json
new file mode 100644
index 0000000..94e3115
--- /dev/null
+++ b/src/enm/study-NWKI-daba0539-9011-4d0a-90d4-556ebd9d1a46.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-daba0539-9011-4d0a-90d4-556ebd9d1a46",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-144a9226-4b93-36a9-ba2d-6b6c4903357b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "sfMEM"
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 160
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-daea095e-5bc5-4f7a-9955-3ea3f5987627.json b/src/enm/study-NWKI-daea095e-5bc5-4f7a-9955-3ea3f5987627.json
new file mode 100644
index 0000000..c70eb84
--- /dev/null
+++ b/src/enm/study-NWKI-daea095e-5bc5-4f7a-9955-3ea3f5987627.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-daea095e-5bc5-4f7a-9955-3ea3f5987627",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-506de59a-ae92-361b-a934-0fdfa41101c0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DVT680-2DProtamine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "VT680"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "VT680"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-db709cf9-ea1c-469d-b877-19ab2945430c.json b/src/enm/study-NWKI-db709cf9-ea1c-469d-b877-19ab2945430c.json
new file mode 100644
index 0000000..5505dac
--- /dev/null
+++ b/src/enm/study-NWKI-db709cf9-ea1c-469d-b877-19ab2945430c.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-db709cf9-ea1c-469d-b877-19ab2945430c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4dd2cfcb-0daf-33f7-ba67-f629e3019271"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -56
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-db74fd62-6078-4d38-acf0-c905ddd6f566.json b/src/enm/study-NWKI-db74fd62-6078-4d38-acf0-c905ddd6f566.json
new file mode 100644
index 0000000..88ab243
--- /dev/null
+++ b/src/enm/study-NWKI-db74fd62-6078-4d38-acf0-c905ddd6f566.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-db74fd62-6078-4d38-acf0-c905ddd6f566",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-705f070c-0c34-3638-803b-c5e85749bf53"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 32.7,
+ "errorValue": 8.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-db7f8f08-cfb5-434d-a143-e629224adfec.json b/src/enm/study-NWKI-db7f8f08-cfb5-434d-a143-e629224adfec.json
new file mode 100644
index 0000000..aea14e0
--- /dev/null
+++ b/src/enm/study-NWKI-db7f8f08-cfb5-434d-a143-e629224adfec.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-db7f8f08-cfb5-434d-a143-e629224adfec",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a28e83ea-54da-3391-9bca-4a8891680403"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 5.6,
+ "errorValue": 0.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-dbe3c3e5-d791-431b-b958-7e6330adee08.json b/src/enm/study-NWKI-dbe3c3e5-d791-431b-b958-7e6330adee08.json
new file mode 100644
index 0000000..5ddef68
--- /dev/null
+++ b/src/enm/study-NWKI-dbe3c3e5-d791-431b-b958-7e6330adee08.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-dbe3c3e5-d791-431b-b958-7e6330adee08",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8c5b9350-2c03-3173-9615-cabfbe6929c9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "BET",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 200
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-dcbe96d3-af8b-48e5-94c2-7c081c1b978a.json b/src/enm/study-NWKI-dcbe96d3-af8b-48e5-94c2-7c081c1b978a.json
new file mode 100644
index 0000000..41f3fda
--- /dev/null
+++ b/src/enm/study-NWKI-dcbe96d3-af8b-48e5-94c2-7c081c1b978a.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-dcbe96d3-af8b-48e5-94c2-7c081c1b978a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b4d33a5-b573-3dbe-9ec3-9d2a9bc42a2e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 86.8,
+ "errorValue": 9.83
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-dcebdf50-3012-4f47-920f-e1b23004e3c2.json b/src/enm/study-NWKI-dcebdf50-3012-4f47-920f-e1b23004e3c2.json
new file mode 100644
index 0000000..59752b6
--- /dev/null
+++ b/src/enm/study-NWKI-dcebdf50-3012-4f47-920f-e1b23004e3c2.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-dcebdf50-3012-4f47-920f-e1b23004e3c2",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8f7f774c-d727-33a9-adc6-9068524faf1c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 36
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-dd496293-9be8-440a-bc07-9291cd70f0ac.json b/src/enm/study-NWKI-dd496293-9be8-440a-bc07-9291cd70f0ac.json
new file mode 100644
index 0000000..f77e90b
--- /dev/null
+++ b/src/enm/study-NWKI-dd496293-9be8-440a-bc07-9291cd70f0ac.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-dd496293-9be8-440a-bc07-9291cd70f0ac",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-144a9226-4b93-36a9-ba2d-6b6c4903357b"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "Serum": {
+ "loValue": "PBS"
+ },
+ "pH": {
+ "loValue": 7.11
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -22.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-dd500fc2-bd1d-4d86-8287-c900b9ea8e2e.json b/src/enm/study-NWKI-dd500fc2-bd1d-4d86-8287-c900b9ea8e2e.json
new file mode 100644
index 0000000..93c183c
--- /dev/null
+++ b/src/enm/study-NWKI-dd500fc2-bd1d-4d86-8287-c900b9ea8e2e.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-dd500fc2-bd1d-4d86-8287-c900b9ea8e2e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d1c31022-c044-30fa-931e-07d96b6f04b5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loQualifier": ">=",
+ "loValue": 45,
+ "upQualifier": "<=",
+ "upValue": 43
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-dd55b7cb-0a21-4d3c-98f7-fe0d8d20f242.json b/src/enm/study-NWKI-dd55b7cb-0a21-4d3c-98f7-fe0d8d20f242.json
new file mode 100644
index 0000000..9ee7bf3
--- /dev/null
+++ b/src/enm/study-NWKI-dd55b7cb-0a21-4d3c-98f7-fe0d8d20f242.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-dd55b7cb-0a21-4d3c-98f7-fe0d8d20f242",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 150,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-dd5da5bf-8a6f-44c0-9779-5fd77bb917e1.json b/src/enm/study-NWKI-dd5da5bf-8a6f-44c0-9779-5fd77bb917e1.json
new file mode 100644
index 0000000..d118e46
--- /dev/null
+++ b/src/enm/study-NWKI-dd5da5bf-8a6f-44c0-9779-5fd77bb917e1.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-dd5da5bf-8a6f-44c0-9779-5fd77bb917e1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 50,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ddc8bdc0-b096-4f84-93ae-9f97c6c45e49.json b/src/enm/study-NWKI-ddc8bdc0-b096-4f84-93ae-9f97c6c45e49.json
new file mode 100644
index 0000000..191f580
--- /dev/null
+++ b/src/enm/study-NWKI-ddc8bdc0-b096-4f84-93ae-9f97c6c45e49.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-ddc8bdc0-b096-4f84-93ae-9f97c6c45e49",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bbb67d89-eaff-38ab-ba4f-403bfb064a0c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DED-2DSuccAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Succinylated_Amino_SPARK680"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Succinylated_Amino_SPARK680"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-de386b5b-748e-498c-9d9a-2b344e887980.json b/src/enm/study-NWKI-de386b5b-748e-498c-9d9a-2b344e887980.json
new file mode 100644
index 0000000..eb5a8c1
--- /dev/null
+++ b/src/enm/study-NWKI-de386b5b-748e-498c-9d9a-2b344e887980.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-de386b5b-748e-498c-9d9a-2b344e887980",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 18
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-de90d49e-4055-46b1-9c9f-3106a61306d8.json b/src/enm/study-NWKI-de90d49e-4055-46b1-9c9f-3106a61306d8.json
new file mode 100644
index 0000000..efd15e7
--- /dev/null
+++ b/src/enm/study-NWKI-de90d49e-4055-46b1-9c9f-3106a61306d8.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-de90d49e-4055-46b1-9c9f-3106a61306d8",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ae63c430-7a80-35c3-828d-c859d81ce698"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 132,
+ "errorValue": 11
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-deb78580-7dbc-452a-a12b-e4b55b84ff8f.json b/src/enm/study-NWKI-deb78580-7dbc-452a-a12b-e4b55b84ff8f.json
new file mode 100644
index 0000000..d5476b2
--- /dev/null
+++ b/src/enm/study-NWKI-deb78580-7dbc-452a-a12b-e4b55b84ff8f.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-deb78580-7dbc-452a-a12b-e4b55b84ff8f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c8d9772c-e50e-3c71-986c-e45692150d71"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DCOOH"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-df09fcef-098d-4e01-9d19-0304cd36e96d.json b/src/enm/study-NWKI-df09fcef-098d-4e01-9d19-0304cd36e96d.json
new file mode 100644
index 0000000..3ea6823
--- /dev/null
+++ b/src/enm/study-NWKI-df09fcef-098d-4e01-9d19-0304cd36e96d.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-df09fcef-098d-4e01-9d19-0304cd36e96d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ad1d5068-29cd-3d8c-9ed0-44ed4ce06ddd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DVT680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-df697673-f97c-4bc6-9187-ea0a8cad201c.json b/src/enm/study-NWKI-df697673-f97c-4bc6-9187-ea0a8cad201c.json
new file mode 100644
index 0000000..05f6d7f
--- /dev/null
+++ b/src/enm/study-NWKI-df697673-f97c-4bc6-9187-ea0a8cad201c.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-df697673-f97c-4bc6-9187-ea0a8cad201c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ca37d03d-af78-3982-8ca0-76025e71fcf1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.87
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-dfd0dabb-2867-4d2b-92c4-f80fc12f933f.json b/src/enm/study-NWKI-dfd0dabb-2867-4d2b-92c4-f80fc12f933f.json
new file mode 100644
index 0000000..bdd8da8
--- /dev/null
+++ b/src/enm/study-NWKI-dfd0dabb-2867-4d2b-92c4-f80fc12f933f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-dfd0dabb-2867-4d2b-92c4-f80fc12f933f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 10,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e0b3dbc7-92eb-47b2-bacc-66c8ee3e589b.json b/src/enm/study-NWKI-e0b3dbc7-92eb-47b2-bacc-66c8ee3e589b.json
new file mode 100644
index 0000000..f0b859a
--- /dev/null
+++ b/src/enm/study-NWKI-e0b3dbc7-92eb-47b2-bacc-66c8ee3e589b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-e0b3dbc7-92eb-47b2-bacc-66c8ee3e589b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 12.5,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e1028d25-5223-4684-b42a-bbdcbbdbfedd.json b/src/enm/study-NWKI-e1028d25-5223-4684-b42a-bbdcbbdbfedd.json
new file mode 100644
index 0000000..2bed1d3
--- /dev/null
+++ b/src/enm/study-NWKI-e1028d25-5223-4684-b42a-bbdcbbdbfedd.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-e1028d25-5223-4684-b42a-bbdcbbdbfedd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b5385309-1812-33ad-a4cf-66d8d3a26bcc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 99,
+ "errorValue": 9
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e140d5a5-9f7f-455e-a1c9-82ae07a4ba3e.json b/src/enm/study-NWKI-e140d5a5-9f7f-455e-a1c9-82ae07a4ba3e.json
new file mode 100644
index 0000000..e6b0e45
--- /dev/null
+++ b/src/enm/study-NWKI-e140d5a5-9f7f-455e-a1c9-82ae07a4ba3e.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-e140d5a5-9f7f-455e-a1c9-82ae07a4ba3e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4dd2cfcb-0daf-33f7-ba67-f629e3019271"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
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diff --git a/src/enm/study-NWKI-e147c87e-1b3f-4f86-96b9-20917e46a195.json b/src/enm/study-NWKI-e147c87e-1b3f-4f86-96b9-20917e46a195.json
new file mode 100644
index 0000000..bf2dfb2
--- /dev/null
+++ b/src/enm/study-NWKI-e147c87e-1b3f-4f86-96b9-20917e46a195.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-e147c87e-1b3f-4f86-96b9-20917e46a195",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ea2bb63b-fd2a-32c2-a41a-d0280abaf29f"
+ },
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
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+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
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+ "Cell line": "Escherichia coli cells"
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+ "loValue": 3.51
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diff --git a/src/enm/study-NWKI-e1a5e9f3-2a77-4fb7-80b2-e84689f62c50.json b/src/enm/study-NWKI-e1a5e9f3-2a77-4fb7-80b2-e84689f62c50.json
new file mode 100644
index 0000000..f84dccc
--- /dev/null
+++ b/src/enm/study-NWKI-e1a5e9f3-2a77-4fb7-80b2-e84689f62c50.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-e1a5e9f3-2a77-4fb7-80b2-e84689f62c50",
+ "owner": {
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+ "name": "NanoWiki"
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+ "owner": "NanoWiki"
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+ "topcategory": "P-CHEM",
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+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
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+ "loValue": "Fe3O4"
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+ "textValue": "Fe3O4"
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+ {
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+ "loQualifier": " ",
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+ "loQualifier": " ",
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
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+ "textValue": "Cross-2Dlinked_dextran"
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diff --git a/src/enm/study-NWKI-e1b6ba8e-5535-43b7-b82d-8356c6004d19.json b/src/enm/study-NWKI-e1b6ba8e-5535-43b7-b82d-8356c6004d19.json
new file mode 100644
index 0000000..e0c118b
--- /dev/null
+++ b/src/enm/study-NWKI-e1b6ba8e-5535-43b7-b82d-8356c6004d19.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-e1b6ba8e-5535-43b7-b82d-8356c6004d19",
+ "owner": {
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
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+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
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diff --git a/src/enm/study-NWKI-e21b970a-2792-4017-bb1b-f2446adad084.json b/src/enm/study-NWKI-e21b970a-2792-4017-bb1b-f2446adad084.json
new file mode 100644
index 0000000..ebbe332
--- /dev/null
+++ b/src/enm/study-NWKI-e21b970a-2792-4017-bb1b-f2446adad084.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-e21b970a-2792-4017-bb1b-f2446adad084",
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+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1021/nn2021056",
+ "year": "0",
+ "owner": "NanoWiki"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
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diff --git a/src/enm/study-NWKI-e22dd986-7128-4270-ad57-28d619a2db06.json b/src/enm/study-NWKI-e22dd986-7128-4270-ad57-28d619a2db06.json
new file mode 100644
index 0000000..0def525
--- /dev/null
+++ b/src/enm/study-NWKI-e22dd986-7128-4270-ad57-28d619a2db06.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-e22dd986-7128-4270-ad57-28d619a2db06",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7181cc57-548a-3117-b59a-bfff2933c0b5"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
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+ "title": "http://dx.doi.org/10.3109/17435390.2015.1017022",
+ "year": "0",
+ "owner": "NanoWiki"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Average Length",
+ "guideline": [
+ ""
+ ]
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+ "parameters": {
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diff --git a/src/enm/study-NWKI-e2383ba1-c0f4-4bc1-9050-279188cbb332.json b/src/enm/study-NWKI-e2383ba1-c0f4-4bc1-9050-279188cbb332.json
new file mode 100644
index 0000000..1577a9b
--- /dev/null
+++ b/src/enm/study-NWKI-e2383ba1-c0f4-4bc1-9050-279188cbb332.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-e2383ba1-c0f4-4bc1-9050-279188cbb332",
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+ "year": "0",
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+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
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+ },
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+ "DISTRIBUTION_TYPE": null,
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+ "loQualifier": ">=",
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+ "upQualifier": "<=",
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+}
diff --git a/src/enm/study-NWKI-e26d4379-6272-4aed-80f4-68e4c557dca5.json b/src/enm/study-NWKI-e26d4379-6272-4aed-80f4-68e4c557dca5.json
new file mode 100644
index 0000000..a56bd96
--- /dev/null
+++ b/src/enm/study-NWKI-e26d4379-6272-4aed-80f4-68e4c557dca5.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-e26d4379-6272-4aed-80f4-68e4c557dca5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-aeeb6004-b180-3b01-a9ab-68b64e19011b"
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+ "name": "NanoWiki"
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+ "title": "http://dx.doi.org/10.1021/nn2021056",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
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+ },
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diff --git a/src/enm/study-NWKI-e30588db-ff9b-42fa-ae5f-eba1238b82aa.json b/src/enm/study-NWKI-e30588db-ff9b-42fa-ae5f-eba1238b82aa.json
new file mode 100644
index 0000000..30c316e
--- /dev/null
+++ b/src/enm/study-NWKI-e30588db-ff9b-42fa-ae5f-eba1238b82aa.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-e30588db-ff9b-42fa-ae5f-eba1238b82aa",
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+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
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+ },
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+ }
+ }
+ ]
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diff --git a/src/enm/study-NWKI-e30bfa97-fb24-4adc-a85c-e377c1f4a28b.json b/src/enm/study-NWKI-e30bfa97-fb24-4adc-a85c-e377c1f4a28b.json
new file mode 100644
index 0000000..165a2a6
--- /dev/null
+++ b/src/enm/study-NWKI-e30bfa97-fb24-4adc-a85c-e377c1f4a28b.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-e30bfa97-fb24-4adc-a85c-e377c1f4a28b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0a6e319e-71fc-37f7-b88d-fbda2e07ccc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
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+ "Method details": null,
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+ },
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+ },
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+ "loValue": 44,
+ "errorValue": 1.8
+ }
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+}
diff --git a/src/enm/study-NWKI-e320cebf-22f8-447a-9546-62c66dff6321.json b/src/enm/study-NWKI-e320cebf-22f8-447a-9546-62c66dff6321.json
new file mode 100644
index 0000000..8299932
--- /dev/null
+++ b/src/enm/study-NWKI-e320cebf-22f8-447a-9546-62c66dff6321.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-e320cebf-22f8-447a-9546-62c66dff6321",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
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+ },
+ "interpretation": {
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+ "effects": [
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+ "conditions": {
+ "Doses/concentrations": {
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+ "unit": "mg/L"
+ }
+ },
+ "result": {
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+ "loValue": 0.0
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+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e32cde8a-54cd-420c-9af5-7b6aa10f7709.json b/src/enm/study-NWKI-e32cde8a-54cd-420c-9af5-7b6aa10f7709.json
new file mode 100644
index 0000000..6b033ab
--- /dev/null
+++ b/src/enm/study-NWKI-e32cde8a-54cd-420c-9af5-7b6aa10f7709.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-e32cde8a-54cd-420c-9af5-7b6aa10f7709",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 150,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e33e16a3-e454-4cb2-bcc4-38d655c6eebd.json b/src/enm/study-NWKI-e33e16a3-e454-4cb2-bcc4-38d655c6eebd.json
new file mode 100644
index 0000000..d477778
--- /dev/null
+++ b/src/enm/study-NWKI-e33e16a3-e454-4cb2-bcc4-38d655c6eebd.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-e33e16a3-e454-4cb2-bcc4-38d655c6eebd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ff85c0ea-c908-35c8-9f1c-bfd037800a31"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 31.2,
+ "errorValue": 4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e3c1dfe2-2c80-4060-8c50-af6421bfd759.json b/src/enm/study-NWKI-e3c1dfe2-2c80-4060-8c50-af6421bfd759.json
new file mode 100644
index 0000000..b76ae6c
--- /dev/null
+++ b/src/enm/study-NWKI-e3c1dfe2-2c80-4060-8c50-af6421bfd759.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-e3c1dfe2-2c80-4060-8c50-af6421bfd759",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e518c122-5f4f-3611-8b30-56b671883e5c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -6.75
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e43d32f2-ae16-4616-bf39-1621decccad1.json b/src/enm/study-NWKI-e43d32f2-ae16-4616-bf39-1621decccad1.json
new file mode 100644
index 0000000..00a8569
--- /dev/null
+++ b/src/enm/study-NWKI-e43d32f2-ae16-4616-bf39-1621decccad1.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-e43d32f2-ae16-4616-bf39-1621decccad1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-69b604fb-e892-31ba-a6f5-feb6cb04effb"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e45646a0-dfc1-45c9-84b2-d7ce19efcc2f.json b/src/enm/study-NWKI-e45646a0-dfc1-45c9-84b2-d7ce19efcc2f.json
new file mode 100644
index 0000000..7a6c478
--- /dev/null
+++ b/src/enm/study-NWKI-e45646a0-dfc1-45c9-84b2-d7ce19efcc2f.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-e45646a0-dfc1-45c9-84b2-d7ce19efcc2f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-44b3fa7b-1667-3f4a-9e31-7a5202320cf3"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -48.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e48a654a-65fd-429c-b366-efbd13e1d798.json b/src/enm/study-NWKI-e48a654a-65fd-429c-b366-efbd13e1d798.json
new file mode 100644
index 0000000..a6e0e24
--- /dev/null
+++ b/src/enm/study-NWKI-e48a654a-65fd-429c-b366-efbd13e1d798.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-e48a654a-65fd-429c-b366-efbd13e1d798",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0494174f-9fc2-3296-8ffb-4fadaceb0348"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 18,
+ "errorValue": 5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e49fd474-935c-4ca5-b755-884722787ee5.json b/src/enm/study-NWKI-e49fd474-935c-4ca5-b755-884722787ee5.json
new file mode 100644
index 0000000..142f11d
--- /dev/null
+++ b/src/enm/study-NWKI-e49fd474-935c-4ca5-b755-884722787ee5.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-e49fd474-935c-4ca5-b755-884722787ee5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6cab56b4-69d9-36e0-8c17-f467d08b2555"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e4bf86b6-5269-409e-a8ae-f551158f8cb3.json b/src/enm/study-NWKI-e4bf86b6-5269-409e-a8ae-f551158f8cb3.json
new file mode 100644
index 0000000..94d859a
--- /dev/null
+++ b/src/enm/study-NWKI-e4bf86b6-5269-409e-a8ae-f551158f8cb3.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-e4bf86b6-5269-409e-a8ae-f551158f8cb3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-02981dd4-b7d0-34c8-a0ab-dd19a5a40865"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
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+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe3O4"
+ },
+ "Remark": null,
+ "TYPE": {
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+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "DextranCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Dextran"
+ },
+ "ELEMENT_OR_GROUP": {
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+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e536a891-5802-420c-8cfa-c23251726ee4.json b/src/enm/study-NWKI-e536a891-5802-420c-8cfa-c23251726ee4.json
new file mode 100644
index 0000000..3e57dd7
--- /dev/null
+++ b/src/enm/study-NWKI-e536a891-5802-420c-8cfa-c23251726ee4.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-e536a891-5802-420c-8cfa-c23251726ee4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4fa19c49-f3b1-3e34-8aa4-3da258933bf8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12.8,
+ "errorValue": 3.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e5772c16-6c45-4b96-8873-b920f0af25de.json b/src/enm/study-NWKI-e5772c16-6c45-4b96-8873-b920f0af25de.json
new file mode 100644
index 0000000..568f70f
--- /dev/null
+++ b/src/enm/study-NWKI-e5772c16-6c45-4b96-8873-b920f0af25de.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-e5772c16-6c45-4b96-8873-b920f0af25de",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-863267cf-faf0-349b-8046-6074d2e718b5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.soilbio.2013.01.016",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 61
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e5f9a72e-5f64-4fa9-b350-a64ec8ada63f.json b/src/enm/study-NWKI-e5f9a72e-5f64-4fa9-b350-a64ec8ada63f.json
new file mode 100644
index 0000000..2d503fe
--- /dev/null
+++ b/src/enm/study-NWKI-e5f9a72e-5f64-4fa9-b350-a64ec8ada63f.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-e5f9a72e-5f64-4fa9-b350-a64ec8ada63f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-506de59a-ae92-361b-a934-0fdfa41101c0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -6.11
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e623f359-40a7-45d7-8dd2-703a80de86c4.json b/src/enm/study-NWKI-e623f359-40a7-45d7-8dd2-703a80de86c4.json
new file mode 100644
index 0000000..5b68e62
--- /dev/null
+++ b/src/enm/study-NWKI-e623f359-40a7-45d7-8dd2-703a80de86c4.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-e623f359-40a7-45d7-8dd2-703a80de86c4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-916751bb-8457-3844-87c0-ada4c6afd1ab"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "Serum": {
+ "loValue": "cMEM"
+ },
+ "pH": {
+ "loValue": 7.83
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e66100d6-ab2b-4207-9ed1-aae1e2a8caf4.json b/src/enm/study-NWKI-e66100d6-ab2b-4207-9ed1-aae1e2a8caf4.json
new file mode 100644
index 0000000..e4e1814
--- /dev/null
+++ b/src/enm/study-NWKI-e66100d6-ab2b-4207-9ed1-aae1e2a8caf4.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-e66100d6-ab2b-4207-9ed1-aae1e2a8caf4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 0.75,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e66557c3-f380-4f87-ad2c-7a943571224a.json b/src/enm/study-NWKI-e66557c3-f380-4f87-ad2c-7a943571224a.json
new file mode 100644
index 0000000..7cc85b4
--- /dev/null
+++ b/src/enm/study-NWKI-e66557c3-f380-4f87-ad2c-7a943571224a.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-e66557c3-f380-4f87-ad2c-7a943571224a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-7031754f-5bb6-3594-8a32-0c03256cdf61"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -47.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e6c69c36-e724-4af9-8501-a313510dc632.json b/src/enm/study-NWKI-e6c69c36-e724-4af9-8501-a313510dc632.json
new file mode 100644
index 0000000..3f78d76
--- /dev/null
+++ b/src/enm/study-NWKI-e6c69c36-e724-4af9-8501-a313510dc632.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-e6c69c36-e724-4af9-8501-a313510dc632",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a968835-50ab-33df-bf5e-42de32d01c15"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e754b05e-be94-4cce-a33d-19173e404ca1.json b/src/enm/study-NWKI-e754b05e-be94-4cce-a33d-19173e404ca1.json
new file mode 100644
index 0000000..6176831
--- /dev/null
+++ b/src/enm/study-NWKI-e754b05e-be94-4cce-a33d-19173e404ca1.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-e754b05e-be94-4cce-a33d-19173e404ca1",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-83a75181-9103-3ef9-aec7-fa38074580f6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -71.8,
+ "errorValue": 11.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e7692ca8-09d6-4c84-a069-6f57200ab2e0.json b/src/enm/study-NWKI-e7692ca8-09d6-4c84-a069-6f57200ab2e0.json
new file mode 100644
index 0000000..807770a
--- /dev/null
+++ b/src/enm/study-NWKI-e7692ca8-09d6-4c84-a069-6f57200ab2e0.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-e7692ca8-09d6-4c84-a069-6f57200ab2e0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8a968835-50ab-33df-bf5e-42de32d01c15"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 102
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e79f5a52-5c63-4532-87d0-62e15f4ea72b.json b/src/enm/study-NWKI-e79f5a52-5c63-4532-87d0-62e15f4ea72b.json
new file mode 100644
index 0000000..cab652d
--- /dev/null
+++ b/src/enm/study-NWKI-e79f5a52-5c63-4532-87d0-62e15f4ea72b.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-e79f5a52-5c63-4532-87d0-62e15f4ea72b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-395bf212-b710-3385-9c23-715a7055b015"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "LDH Release",
+ "guideline": [
+ "Lactate Dehydrogenase Activity"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Lactate Dehydrogenase Activity"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "LDH_Release",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e802e276-7b5c-46b5-b825-5e61aa184245.json b/src/enm/study-NWKI-e802e276-7b5c-46b5-b825-5e61aa184245.json
new file mode 100644
index 0000000..7e73a9e
--- /dev/null
+++ b/src/enm/study-NWKI-e802e276-7b5c-46b5-b825-5e61aa184245.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-e802e276-7b5c-46b5-b825-5e61aa184245",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 24
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 15
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e84ae886-79f5-4736-b2ff-187f21424841.json b/src/enm/study-NWKI-e84ae886-79f5-4736-b2ff-187f21424841.json
new file mode 100644
index 0000000..18949fe
--- /dev/null
+++ b/src/enm/study-NWKI-e84ae886-79f5-4736-b2ff-187f21424841.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-e84ae886-79f5-4736-b2ff-187f21424841",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d8f70c6c-3496-3ad3-8ab3-e4f08a178d30"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 150,
+ "errorValue": 0.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e87408ad-fb53-45b5-88ce-d6c95bcefafb.json b/src/enm/study-NWKI-e87408ad-fb53-45b5-88ce-d6c95bcefafb.json
new file mode 100644
index 0000000..6e15872
--- /dev/null
+++ b/src/enm/study-NWKI-e87408ad-fb53-45b5-88ce-d6c95bcefafb.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-e87408ad-fb53-45b5-88ce-d6c95bcefafb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93603a1-8e0d-372a-8acf-48533b86ecb5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "Concentration in cell",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_cell",
+ "conditions": {
+ "Concentration in culture medium": {
+ "loValue": 100,
+ "unit": "ng/g"
+ },
+ "Time": {
+ "loValue": 1,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 27
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e8912d4d-3491-46ef-8171-8fe1442e9136.json b/src/enm/study-NWKI-e8912d4d-3491-46ef-8171-8fe1442e9136.json
new file mode 100644
index 0000000..7cd5346
--- /dev/null
+++ b/src/enm/study-NWKI-e8912d4d-3491-46ef-8171-8fe1442e9136.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-e8912d4d-3491-46ef-8171-8fe1442e9136",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93a9eb3-83df-3522-b417-7b3a379054a6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Diameter",
+ "guideline": [
+ ""
+ ]
+ },
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+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "endpoint": "Diameter",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 9.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e8a0ef87-e997-4b5c-8e9d-38d04fc062a5.json b/src/enm/study-NWKI-e8a0ef87-e997-4b5c-8e9d-38d04fc062a5.json
new file mode 100644
index 0000000..7fdb358
--- /dev/null
+++ b/src/enm/study-NWKI-e8a0ef87-e997-4b5c-8e9d-38d04fc062a5.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-e8a0ef87-e997-4b5c-8e9d-38d04fc062a5",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-2a046d54-ea47-31b2-a370-e886e5a0a6bb"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
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+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
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+ "SAMPLING": null,
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+ },
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+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "loQualifier": " ",
+ "loValue": "BiotinCoating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "RCOOH"
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+ "ELEMENT_OR_GROUP": {
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+ "loValue": "O=CO[H]"
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+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "RCOOH"
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+ ]
+}
diff --git a/src/enm/study-NWKI-e8a71c08-fd85-4399-af9f-bc3233a8e111.json b/src/enm/study-NWKI-e8a71c08-fd85-4399-af9f-bc3233a8e111.json
new file mode 100644
index 0000000..a6c96f7
--- /dev/null
+++ b/src/enm/study-NWKI-e8a71c08-fd85-4399-af9f-bc3233a8e111.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-e8a71c08-fd85-4399-af9f-bc3233a8e111",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3481f716-18fa-39b3-aa54-4acb67877194"
+ },
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
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+ "Method details": null,
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+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "loValue": "CLIO-2DGlycine"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Glycine"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "C(C(=O)O)N"
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+ "loValue": "COATING"
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+ },
+ "result": {
+ "unit": null,
+ "textValue": "Glycine"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e8fcf88e-c52d-4be4-992d-fd731ffc5144.json b/src/enm/study-NWKI-e8fcf88e-c52d-4be4-992d-fd731ffc5144.json
new file mode 100644
index 0000000..6e24069
--- /dev/null
+++ b/src/enm/study-NWKI-e8fcf88e-c52d-4be4-992d-fd731ffc5144.json
@@ -0,0 +1,73 @@
+{
+ "uuid": "NWKI-e8fcf88e-c52d-4be4-992d-fd731ffc5144",
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+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
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+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ },
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+ "loValue": "COOH-2DAmphPolymer"
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+ "DESCRIPTION": {
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+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "COOH"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e93beeb2-1448-497f-9931-56afc2834747.json b/src/enm/study-NWKI-e93beeb2-1448-497f-9931-56afc2834747.json
new file mode 100644
index 0000000..896a987
--- /dev/null
+++ b/src/enm/study-NWKI-e93beeb2-1448-497f-9931-56afc2834747.json
@@ -0,0 +1,55 @@
+{
+ "uuid": "NWKI-e93beeb2-1448-497f-9931-56afc2834747",
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_MELTING_SECTION",
+ "term": "http://semanticscience.org/resource/CHEMINF_000256",
+ "title": "4.2 Melting point / freezing point"
+ },
+ "endpoint": "Melting Point",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "endpoint": "Melting Point",
+ "conditions": {
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+ "Sublimation": null
+ },
+ "result": {
+ "unit": "°C",
+ "loQualifier": ">=",
+ "loValue": 1600
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e950a396-9e0d-43e3-a6fd-9d3b5c32f83e.json b/src/enm/study-NWKI-e950a396-9e0d-43e3-a6fd-9d3b5c32f83e.json
new file mode 100644
index 0000000..43a4885
--- /dev/null
+++ b/src/enm/study-NWKI-e950a396-9e0d-43e3-a6fd-9d3b5c32f83e.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-e950a396-9e0d-43e3-a6fd-9d3b5c32f83e",
+ "owner": {
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+ "name": "NanoWiki"
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+ "year": "0",
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+ },
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+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 29.5,
+ "errorValue": 6.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e96f3a5f-d334-4e90-9523-ed67d33e6f76.json b/src/enm/study-NWKI-e96f3a5f-d334-4e90-9523-ed67d33e6f76.json
new file mode 100644
index 0000000..c2d3147
--- /dev/null
+++ b/src/enm/study-NWKI-e96f3a5f-d334-4e90-9523-ed67d33e6f76.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-e96f3a5f-d334-4e90-9523-ed67d33e6f76",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-09e3ff87-f9a0-34dc-955e-e8b8474fb12b"
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+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.envpol.2008.11.004",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
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+ "effects": [
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+ "endpoint": "PARTICLE SIZE",
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+ },
+ "result": {
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+ "loValue": 285
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e9ae71d3-fd50-4f4e-bef9-9063b1f1297d.json b/src/enm/study-NWKI-e9ae71d3-fd50-4f4e-bef9-9063b1f1297d.json
new file mode 100644
index 0000000..ace4bbb
--- /dev/null
+++ b/src/enm/study-NWKI-e9ae71d3-fd50-4f4e-bef9-9063b1f1297d.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-e9ae71d3-fd50-4f4e-bef9-9063b1f1297d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-605f4f43-028b-3a42-ae94-9852a9f6f5f8"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ "Type of method": null
+ },
+ "reliability": {
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+ },
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+ },
+ "effects": [
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+ "endpoint": "ZETA POTENTIAL",
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+ "pH": {
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+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -48,
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e9c11fe6-5416-4cfc-a156-9a90788b2709.json b/src/enm/study-NWKI-e9c11fe6-5416-4cfc-a156-9a90788b2709.json
new file mode 100644
index 0000000..f647097
--- /dev/null
+++ b/src/enm/study-NWKI-e9c11fe6-5416-4cfc-a156-9a90788b2709.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-e9c11fe6-5416-4cfc-a156-9a90788b2709",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0455b6e1-5203-37bb-a98b-20460acceda1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DCY35-2DTat"
+ },
+ "DESCRIPTION": {
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+ "loValue": "Tat"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Tat"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e9eecdcb-5179-4160-8e90-268db1c378a7.json b/src/enm/study-NWKI-e9eecdcb-5179-4160-8e90-268db1c378a7.json
new file mode 100644
index 0000000..28ee2a5
--- /dev/null
+++ b/src/enm/study-NWKI-e9eecdcb-5179-4160-8e90-268db1c378a7.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-e9eecdcb-5179-4160-8e90-268db1c378a7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c5e226b0-d405-32d5-a652-7f7f1f0eb55d"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "TESTMAT_FORM": null
+ },
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+ "r_isUsedforClassification": "false",
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+ },
+ "interpretation": {
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+ },
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+ {
+ "endpoint": "PARTICLE SIZE",
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+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 91.9,
+ "errorValue": 4.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-e9f56dd0-29d1-4ddc-a4fe-6c740f8a07de.json b/src/enm/study-NWKI-e9f56dd0-29d1-4ddc-a4fe-6c740f8a07de.json
new file mode 100644
index 0000000..33cac40
--- /dev/null
+++ b/src/enm/study-NWKI-e9f56dd0-29d1-4ddc-a4fe-6c740f8a07de.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-e9f56dd0-29d1-4ddc-a4fe-6c740f8a07de",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fdab53f4-57f3-3501-9bfc-a4ae95c4ec44"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Colon HT29",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 8
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ea31baba-b673-423e-a37c-4b9d21494550.json b/src/enm/study-NWKI-ea31baba-b673-423e-a37c-4b9d21494550.json
new file mode 100644
index 0000000..e0ca260
--- /dev/null
+++ b/src/enm/study-NWKI-ea31baba-b673-423e-a37c-4b9d21494550.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-ea31baba-b673-423e-a37c-4b9d21494550",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4beee533-65e4-364a-adb7-7a520180de61"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "ZnO"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "ZnO"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Triethoxycaprylsilane_Coating"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "Triethoxycaprylsilane"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Triethoxycaprylsilane"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ea56f38e-663f-4bdc-ab4a-1d9f204e7477.json b/src/enm/study-NWKI-ea56f38e-663f-4bdc-ab4a-1d9f204e7477.json
new file mode 100644
index 0000000..bced761
--- /dev/null
+++ b/src/enm/study-NWKI-ea56f38e-663f-4bdc-ab4a-1d9f204e7477.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-ea56f38e-663f-4bdc-ab4a-1d9f204e7477",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c7bee4e3-8884-3e29-ad8b-38decf6146fd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -14
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ea6de4e4-954d-44f6-9b52-82cbd8a646a0.json b/src/enm/study-NWKI-ea6de4e4-954d-44f6-9b52-82cbd8a646a0.json
new file mode 100644
index 0000000..03ebde1
--- /dev/null
+++ b/src/enm/study-NWKI-ea6de4e4-954d-44f6-9b52-82cbd8a646a0.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-ea6de4e4-954d-44f6-9b52-82cbd8a646a0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-eb7ec2b5-8964-4b78-88ac-4095399c8b33.json b/src/enm/study-NWKI-eb7ec2b5-8964-4b78-88ac-4095399c8b33.json
new file mode 100644
index 0000000..f51556d
--- /dev/null
+++ b/src/enm/study-NWKI-eb7ec2b5-8964-4b78-88ac-4095399c8b33.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-eb7ec2b5-8964-4b78-88ac-4095399c8b33",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3ccb7313-0905-322a-ac62-09adb667bc0f"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 300
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ebafaab1-1dc2-41af-8065-393cb37943a0.json b/src/enm/study-NWKI-ebafaab1-1dc2-41af-8065-393cb37943a0.json
new file mode 100644
index 0000000..11744ae
--- /dev/null
+++ b/src/enm/study-NWKI-ebafaab1-1dc2-41af-8065-393cb37943a0.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-ebafaab1-1dc2-41af-8065-393cb37943a0",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-bb97285c-a58f-34c0-aa16-d5eac02280fa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -73.7,
+ "errorValue": 17.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ec8a860b-5c0c-4f89-a591-eacdf9757dcd.json b/src/enm/study-NWKI-ec8a860b-5c0c-4f89-a591-eacdf9757dcd.json
new file mode 100644
index 0000000..e27010b
--- /dev/null
+++ b/src/enm/study-NWKI-ec8a860b-5c0c-4f89-a591-eacdf9757dcd.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-ec8a860b-5c0c-4f89-a591-eacdf9757dcd",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-61515bd0-5a80-3428-a093-01be1d677862"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 112,
+ "errorValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ed524437-e91a-4ca4-951c-b3962ee96a20.json b/src/enm/study-NWKI-ed524437-e91a-4ca4-951c-b3962ee96a20.json
new file mode 100644
index 0000000..201fcd5
--- /dev/null
+++ b/src/enm/study-NWKI-ed524437-e91a-4ca4-951c-b3962ee96a20.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-ed524437-e91a-4ca4-951c-b3962ee96a20",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b110d018-6de0-303b-afcc-6a5e1f5911aa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ed96c06b-0775-4992-9d55-9cb401e8b27c.json b/src/enm/study-NWKI-ed96c06b-0775-4992-9d55-9cb401e8b27c.json
new file mode 100644
index 0000000..f176988
--- /dev/null
+++ b/src/enm/study-NWKI-ed96c06b-0775-4992-9d55-9cb401e8b27c.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "NWKI-ed96c06b-0775-4992-9d55-9cb401e8b27c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e518c122-5f4f-3611-8b30-56b671883e5c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DED-2DAminoSPARK680"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PVA"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-edb48b72-618c-48f2-bda2-27e0c54780ca.json b/src/enm/study-NWKI-edb48b72-618c-48f2-bda2-27e0c54780ca.json
new file mode 100644
index 0000000..2d768cf
--- /dev/null
+++ b/src/enm/study-NWKI-edb48b72-618c-48f2-bda2-27e0c54780ca.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-edb48b72-618c-48f2-bda2-27e0c54780ca",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e078849d-6137-33fc-b103-d458cb77184a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "TEM",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 42,
+ "errorValue": 3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ee0e465d-b789-499c-aba3-c7c6f017fec6.json b/src/enm/study-NWKI-ee0e465d-b789-499c-aba3-c7c6f017fec6.json
new file mode 100644
index 0000000..78aa0d0
--- /dev/null
+++ b/src/enm/study-NWKI-ee0e465d-b789-499c-aba3-c7c6f017fec6.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-ee0e465d-b789-499c-aba3-c7c6f017fec6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0b16e14c-47ab-3075-afc4-0713d06aa54c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -16.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ee6e915f-27fe-47f6-b0a2-b6a34d63360c.json b/src/enm/study-NWKI-ee6e915f-27fe-47f6-b0a2-b6a34d63360c.json
new file mode 100644
index 0000000..980fcf6
--- /dev/null
+++ b/src/enm/study-NWKI-ee6e915f-27fe-47f6-b0a2-b6a34d63360c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-ee6e915f-27fe-47f6-b0a2-b6a34d63360c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-57943982-0642-388c-be22-f1770d3b620c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 66
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-eeeeb0a4-1916-4f36-8179-13e6ae2acafb.json b/src/enm/study-NWKI-eeeeb0a4-1916-4f36-8179-13e6ae2acafb.json
new file mode 100644
index 0000000..6e7dee8
--- /dev/null
+++ b/src/enm/study-NWKI-eeeeb0a4-1916-4f36-8179-13e6ae2acafb.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-eeeeb0a4-1916-4f36-8179-13e6ae2acafb",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-812e122b-8bee-350d-8aea-aaaa88ce84dd"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 50,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-eef63f55-589e-4f39-9981-16b5e109b518.json b/src/enm/study-NWKI-eef63f55-589e-4f39-9981-16b5e109b518.json
new file mode 100644
index 0000000..1542ad2
--- /dev/null
+++ b/src/enm/study-NWKI-eef63f55-589e-4f39-9981-16b5e109b518.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-eef63f55-589e-4f39-9981-16b5e109b518",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-82c12809-d7af-3061-a531-1db744c521f0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 37
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ef4230e8-9345-4e2d-8ff8-ab9347a680f4.json b/src/enm/study-NWKI-ef4230e8-9345-4e2d-8ff8-ab9347a680f4.json
new file mode 100644
index 0000000..27959e0
--- /dev/null
+++ b/src/enm/study-NWKI-ef4230e8-9345-4e2d-8ff8-ab9347a680f4.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-ef4230e8-9345-4e2d-8ff8-ab9347a680f4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-52edeff5-900d-3f5a-86ba-550e9b368239"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 5,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ef4d1512-aa17-48f1-be53-08cfb0868848.json b/src/enm/study-NWKI-ef4d1512-aa17-48f1-be53-08cfb0868848.json
new file mode 100644
index 0000000..5504411
--- /dev/null
+++ b/src/enm/study-NWKI-ef4d1512-aa17-48f1-be53-08cfb0868848.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-ef4d1512-aa17-48f1-be53-08cfb0868848",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ef516d0f-83b9-4325-9568-401a03384707.json b/src/enm/study-NWKI-ef516d0f-83b9-4325-9568-401a03384707.json
new file mode 100644
index 0000000..a57ae76
--- /dev/null
+++ b/src/enm/study-NWKI-ef516d0f-83b9-4325-9568-401a03384707.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-ef516d0f-83b9-4325-9568-401a03384707",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-984a9c7f-2372-3b8f-9ff5-93a9f94f2eb7"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn202116p",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 40,
+ "errorValue": 12
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-efd2642b-ae04-4bf4-a43e-d43799c9bdce.json b/src/enm/study-NWKI-efd2642b-ae04-4bf4-a43e-d43799c9bdce.json
new file mode 100644
index 0000000..6118637
--- /dev/null
+++ b/src/enm/study-NWKI-efd2642b-ae04-4bf4-a43e-d43799c9bdce.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-efd2642b-ae04-4bf4-a43e-d43799c9bdce",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 1,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f00c75cc-5a1b-47b5-8ae1-8ae1db6d98ae.json b/src/enm/study-NWKI-f00c75cc-5a1b-47b5-8ae1-8ae1db6d98ae.json
new file mode 100644
index 0000000..6e390b6
--- /dev/null
+++ b/src/enm/study-NWKI-f00c75cc-5a1b-47b5-8ae1-8ae1db6d98ae.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f00c75cc-5a1b-47b5-8ae1-8ae1db6d98ae",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 12.5,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f083093f-b798-43b1-a9a5-774ca6a07ace.json b/src/enm/study-NWKI-f083093f-b798-43b1-a9a5-774ca6a07ace.json
new file mode 100644
index 0000000..993f896
--- /dev/null
+++ b/src/enm/study-NWKI-f083093f-b798-43b1-a9a5-774ca6a07ace.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f083093f-b798-43b1-a9a5-774ca6a07ace",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 50,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f0c20fa3-8c0b-4395-b633-0116213e3792.json b/src/enm/study-NWKI-f0c20fa3-8c0b-4395-b633-0116213e3792.json
new file mode 100644
index 0000000..5ca4601
--- /dev/null
+++ b/src/enm/study-NWKI-f0c20fa3-8c0b-4395-b633-0116213e3792.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-f0c20fa3-8c0b-4395-b633-0116213e3792",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-4358aa69-dec1-387a-b7ea-2238198ccdff"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null,
+ "Serum": {
+ "loValue": "cMEM"
+ }
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 166
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f17de7b3-3545-4488-a373-01a207c8230b.json b/src/enm/study-NWKI-f17de7b3-3545-4488-a373-01a207c8230b.json
new file mode 100644
index 0000000..0f633d7
--- /dev/null
+++ b/src/enm/study-NWKI-f17de7b3-3545-4488-a373-01a207c8230b.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-f17de7b3-3545-4488-a373-01a207c8230b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a2d5a729-4ed1-3f1b-a5fd-3bd090a48aa5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn301622h",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 7
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -56,
+ "errorValue": 5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f1c00d50-7b3c-4380-9611-7796fcb6605a.json b/src/enm/study-NWKI-f1c00d50-7b3c-4380-9611-7796fcb6605a.json
new file mode 100644
index 0000000..eeb7d68
--- /dev/null
+++ b/src/enm/study-NWKI-f1c00d50-7b3c-4380-9611-7796fcb6605a.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f1c00d50-7b3c-4380-9611-7796fcb6605a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8ef21404-e101-37c8-8206-32f526d75012"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f1e1f762-cb0e-4758-8242-9dbeba51898c.json b/src/enm/study-NWKI-f1e1f762-cb0e-4758-8242-9dbeba51898c.json
new file mode 100644
index 0000000..0a77700
--- /dev/null
+++ b/src/enm/study-NWKI-f1e1f762-cb0e-4758-8242-9dbeba51898c.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f1e1f762-cb0e-4758-8242-9dbeba51898c",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-72ead9c0-f7c1-36f4-98c4-92faa7e81863"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 0.375,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f2c1af5b-2d28-4124-a88c-53fefaa4fff6.json b/src/enm/study-NWKI-f2c1af5b-2d28-4124-a88c-53fefaa4fff6.json
new file mode 100644
index 0000000..d3b0335
--- /dev/null
+++ b/src/enm/study-NWKI-f2c1af5b-2d28-4124-a88c-53fefaa4fff6.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f2c1af5b-2d28-4124-a88c-53fefaa4fff6",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-de03994b-9d74-3e39-aa41-e7df34384442"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 50,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f348dc52-e4ed-4222-8b25-8c60b5a9b082.json b/src/enm/study-NWKI-f348dc52-e4ed-4222-8b25-8c60b5a9b082.json
new file mode 100644
index 0000000..a5c5ef3
--- /dev/null
+++ b/src/enm/study-NWKI-f348dc52-e4ed-4222-8b25-8c60b5a9b082.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-f348dc52-e4ed-4222-8b25-8c60b5a9b082",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f3be029d-68f6-310a-87a4-ceffee1b4eda"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Mean Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 62
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f34bd7ea-23f0-4914-9e8d-fc373f03a50e.json b/src/enm/study-NWKI-f34bd7ea-23f0-4914-9e8d-fc373f03a50e.json
new file mode 100644
index 0000000..c8ebcc6
--- /dev/null
+++ b/src/enm/study-NWKI-f34bd7ea-23f0-4914-9e8d-fc373f03a50e.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-f34bd7ea-23f0-4914-9e8d-fc373f03a50e",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d1c31022-c044-30fa-931e-07d96b6f04b5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1080/10934520600966177",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 40,
+ "upQualifier": "<=",
+ "upValue": 47
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f39c022c-a485-442c-8921-f798d46857cc.json b/src/enm/study-NWKI-f39c022c-a485-442c-8921-f798d46857cc.json
new file mode 100644
index 0000000..4250c79
--- /dev/null
+++ b/src/enm/study-NWKI-f39c022c-a485-442c-8921-f798d46857cc.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-f39c022c-a485-442c-8921-f798d46857cc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8667bfb7-a5da-3eb0-b9d7-86e2c8f06f19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 60,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f3f409b5-312e-4c14-bd8b-86983cbb69be.json b/src/enm/study-NWKI-f3f409b5-312e-4c14-bd8b-86983cbb69be.json
new file mode 100644
index 0000000..3c79f57
--- /dev/null
+++ b/src/enm/study-NWKI-f3f409b5-312e-4c14-bd8b-86983cbb69be.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f3f409b5-312e-4c14-bd8b-86983cbb69be",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c4c91023-5b41-3d6d-bb4f-ee1152926be0"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 2500,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 45
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f4b25191-fdc0-42ad-a381-8d7a2d240077.json b/src/enm/study-NWKI-f4b25191-fdc0-42ad-a381-8d7a2d240077.json
new file mode 100644
index 0000000..8b0456d
--- /dev/null
+++ b/src/enm/study-NWKI-f4b25191-fdc0-42ad-a381-8d7a2d240077.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-f4b25191-fdc0-42ad-a381-8d7a2d240077",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-509caa0e-0b8c-30e9-9592-48c6a83fe4ec"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/tx800289z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f574b0be-00ea-4407-b36f-f23425acddc7.json b/src/enm/study-NWKI-f574b0be-00ea-4407-b36f-f23425acddc7.json
new file mode 100644
index 0000000..fe318ef
--- /dev/null
+++ b/src/enm/study-NWKI-f574b0be-00ea-4407-b36f-f23425acddc7.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-f574b0be-00ea-4407-b36f-f23425acddc7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e6ef5597-a3f9-3f21-afff-db5f654ef534"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.29
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f5b23bcd-efc3-4a65-ab24-d34b0d2c6e92.json b/src/enm/study-NWKI-f5b23bcd-efc3-4a65-ab24-d34b0d2c6e92.json
new file mode 100644
index 0000000..fd5296e
--- /dev/null
+++ b/src/enm/study-NWKI-f5b23bcd-efc3-4a65-ab24-d34b0d2c6e92.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f5b23bcd-efc3-4a65-ab24-d34b0d2c6e92",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-0a6e319e-71fc-37f7-b88d-fbda2e07ccc1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.chemosphere.2011.04.067",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "Cell number determination"
+ ]
+ },
+ "parameters": {
+ "Cell line": "HaCaT",
+ "Method type": "Cell number determination"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f5b27205-883e-4ca5-9b36-dcff899424e7.json b/src/enm/study-NWKI-f5b27205-883e-4ca5-9b36-dcff899424e7.json
new file mode 100644
index 0000000..c99a23b
--- /dev/null
+++ b/src/enm/study-NWKI-f5b27205-883e-4ca5-9b36-dcff899424e7.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-f5b27205-883e-4ca5-9b36-dcff899424e7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c10e9034-a37c-37f8-afa4-b0e1081c6856"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 13.5,
+ "errorValue": 4.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f5ca7f44-a8bf-4334-b09e-5ef6d04d3dac.json b/src/enm/study-NWKI-f5ca7f44-a8bf-4334-b09e-5ef6d04d3dac.json
new file mode 100644
index 0000000..fcd5501
--- /dev/null
+++ b/src/enm/study-NWKI-f5ca7f44-a8bf-4334-b09e-5ef6d04d3dac.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-f5ca7f44-a8bf-4334-b09e-5ef6d04d3dac",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-395bf212-b710-3385-9c23-715a7055b015"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "DNA_in_Tail",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 100
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f5e2ff69-a30f-4e11-b174-919b40b307a3.json b/src/enm/study-NWKI-f5e2ff69-a30f-4e11-b174-919b40b307a3.json
new file mode 100644
index 0000000..4ee19d0
--- /dev/null
+++ b/src/enm/study-NWKI-f5e2ff69-a30f-4e11-b174-919b40b307a3.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f5e2ff69-a30f-4e11-b174-919b40b307a3",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-417f0133-8f2c-3255-bdcf-7d71ac295d00"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 100,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f5f44a99-a481-4795-83f3-f4a111bb155d.json b/src/enm/study-NWKI-f5f44a99-a481-4795-83f3-f4a111bb155d.json
new file mode 100644
index 0000000..05a41c4
--- /dev/null
+++ b/src/enm/study-NWKI-f5f44a99-a481-4795-83f3-f4a111bb155d.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-f5f44a99-a481-4795-83f3-f4a111bb155d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e518c122-5f4f-3611-8b30-56b671883e5c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f618f090-2592-422e-834b-c043e330167f.json b/src/enm/study-NWKI-f618f090-2592-422e-834b-c043e330167f.json
new file mode 100644
index 0000000..a62856c
--- /dev/null
+++ b/src/enm/study-NWKI-f618f090-2592-422e-834b-c043e330167f.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-f618f090-2592-422e-834b-c043e330167f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-57a03b07-0bb6-306c-ba30-71d5bc626385"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1016/j.soilbio.2013.01.016",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f698f09b-0fe8-49a5-9653-1e19d87e87d4.json b/src/enm/study-NWKI-f698f09b-0fe8-49a5-9653-1e19d87e87d4.json
new file mode 100644
index 0000000..35709bc
--- /dev/null
+++ b/src/enm/study-NWKI-f698f09b-0fe8-49a5-9653-1e19d87e87d4.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f698f09b-0fe8-49a5-9653-1e19d87e87d4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b110d018-6de0-303b-afcc-6a5e1f5911aa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Specific Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loValue": 90
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f70949ca-c8fc-4c53-9289-cfb49bbe721b.json b/src/enm/study-NWKI-f70949ca-c8fc-4c53-9289-cfb49bbe721b.json
new file mode 100644
index 0000000..af5b6a2
--- /dev/null
+++ b/src/enm/study-NWKI-f70949ca-c8fc-4c53-9289-cfb49bbe721b.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-f70949ca-c8fc-4c53-9289-cfb49bbe721b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ec00c05f-0b35-3c5a-b16f-7a3560213764"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": null,
+ "loValue": -9.34
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f72b366c-8a43-46dc-a05b-1a27ef7bf17d.json b/src/enm/study-NWKI-f72b366c-8a43-46dc-a05b-1a27ef7bf17d.json
new file mode 100644
index 0000000..5acea5b
--- /dev/null
+++ b/src/enm/study-NWKI-f72b366c-8a43-46dc-a05b-1a27ef7bf17d.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-f72b366c-8a43-46dc-a05b-1a27ef7bf17d",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-97103918-5eeb-36a3-9981-3aa6dcef5d4c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 150,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f78a6697-ef20-470a-9472-b92cb085f363.json b/src/enm/study-NWKI-f78a6697-ef20-470a-9472-b92cb085f363.json
new file mode 100644
index 0000000..f1823aa
--- /dev/null
+++ b/src/enm/study-NWKI-f78a6697-ef20-470a-9472-b92cb085f363.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-f78a6697-ef20-470a-9472-b92cb085f363",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-8667bfb7-a5da-3eb0-b9d7-86e2c8f06f19"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3762/bjnano.5.151",
+ "year": "2014",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Percentage Viable Cells",
+ "guideline": [
+ "MTT reduction assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "MTT reduction assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Percentage_Viable_Cells",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 600,
+ "unit": "µg/mL"
+ },
+ "Incubation Time": {
+ "loValue": 4
+ }
+ },
+ "result": {
+ "unit": null,
+ "loValue": 95
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f7a33447-5ffe-43d7-a7cd-744d88a99dde.json b/src/enm/study-NWKI-f7a33447-5ffe-43d7-a7cd-744d88a99dde.json
new file mode 100644
index 0000000..009e69b
--- /dev/null
+++ b/src/enm/study-NWKI-f7a33447-5ffe-43d7-a7cd-744d88a99dde.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-f7a33447-5ffe-43d7-a7cd-744d88a99dde",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ea48c37d-840a-30d2-9740-1198a7e2c3b6"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "Surface Area",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ "Remark": null
+ },
+ "result": {
+ "unit": "m^2/g",
+ "loQualifier": ">=",
+ "loValue": 175,
+ "upQualifier": "<=",
+ "upValue": 225
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f7b60875-d81f-4dcb-87d0-2eaf6608c658.json b/src/enm/study-NWKI-f7b60875-d81f-4dcb-87d0-2eaf6608c658.json
new file mode 100644
index 0000000..5bb85ce
--- /dev/null
+++ b/src/enm/study-NWKI-f7b60875-d81f-4dcb-87d0-2eaf6608c658.json
@@ -0,0 +1,65 @@
+{
+ "uuid": "NWKI-f7b60875-d81f-4dcb-87d0-2eaf6608c658",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-916751bb-8457-3844-87c0-ada4c6afd1ab"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/ja309812z",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "Serum": {
+ "loValue": "sfMEM"
+ },
+ "pH": {
+ "loValue": 8.11
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f7d03856-5343-4baa-ad7a-c1c3722a2e5a.json b/src/enm/study-NWKI-f7d03856-5343-4baa-ad7a-c1c3722a2e5a.json
new file mode 100644
index 0000000..419d383
--- /dev/null
+++ b/src/enm/study-NWKI-f7d03856-5343-4baa-ad7a-c1c3722a2e5a.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-f7d03856-5343-4baa-ad7a-c1c3722a2e5a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c0927a67-d21d-37e8-932d-fb1607e58aee"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390903276933",
+ "year": "2009",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
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+ "code": "BAO_0002167_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002167",
+ "title": "BAO_0002167 Genotoxicity Assay"
+ },
+ "endpoint": "DNA in Tail",
+ "guideline": [
+ "Fpg-2Dmodified Comet Assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "Caco-2 cell",
+ "Method type": "Fpg-2Dmodified Comet Assay"
+ },
+ "reliability": {
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+ "r_value": null
+ },
+ "interpretation": {
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+ "loValue": 20,
+ "unit": "ug/cm^2"
+ },
+ "FPG Content": {
+ "loValue": 100
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f7eebb4f-c892-4007-a01e-e2bad43b52c4.json b/src/enm/study-NWKI-f7eebb4f-c892-4007-a01e-e2bad43b52c4.json
new file mode 100644
index 0000000..27431f9
--- /dev/null
+++ b/src/enm/study-NWKI-f7eebb4f-c892-4007-a01e-e2bad43b52c4.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-f7eebb4f-c892-4007-a01e-e2bad43b52c4",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-5172b34a-a6f6-398f-ace6-1d30e6bc9efa"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
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+ "SAMPLING": null,
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+ "ELEMENT_OR_GROUP": {
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+ "loValue": "Fe3O4"
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+ "unit": null,
+ "textValue": "Fe3O4"
+ }
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+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "CLIO-2DNH2"
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+ "loQualifier": " ",
+ "loValue": "Cross-2Dlinked_dextran"
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+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
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+}
diff --git a/src/enm/study-NWKI-f7f637bc-76dc-43a5-92ed-d770c4e059dc.json b/src/enm/study-NWKI-f7f637bc-76dc-43a5-92ed-d770c4e059dc.json
new file mode 100644
index 0000000..aa6c615
--- /dev/null
+++ b/src/enm/study-NWKI-f7f637bc-76dc-43a5-92ed-d770c4e059dc.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-f7f637bc-76dc-43a5-92ed-d770c4e059dc",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-fd891814-04d2-30bc-a0b6-cc3149bf75ec"
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+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
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+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es9016975",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
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+ "Type of method": null
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+ "Remark": null,
+ "pH": null
+ },
+ "result": {
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+ }
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+}
diff --git a/src/enm/study-NWKI-f803a531-0d74-4334-8b07-4dd5b902f43a.json b/src/enm/study-NWKI-f803a531-0d74-4334-8b07-4dd5b902f43a.json
new file mode 100644
index 0000000..00c1ef4
--- /dev/null
+++ b/src/enm/study-NWKI-f803a531-0d74-4334-8b07-4dd5b902f43a.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-f803a531-0d74-4334-8b07-4dd5b902f43a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d7e38d71-0fcb-3a23-8cbe-aae4ce82b33a"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
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+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
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+ "result": {
+ "unit": "nm",
+ "loValue": 3.37,
+ "errorValue": 0.57
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f888f18c-4f44-4365-94ba-0bdeb0e73501.json b/src/enm/study-NWKI-f888f18c-4f44-4365-94ba-0bdeb0e73501.json
new file mode 100644
index 0000000..9e53eca
--- /dev/null
+++ b/src/enm/study-NWKI-f888f18c-4f44-4365-94ba-0bdeb0e73501.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-f888f18c-4f44-4365-94ba-0bdeb0e73501",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-b6c86895-1b73-39ec-8bd2-0106e77a7673"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
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+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
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+ "SEQ_NUM": null
+ },
+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f88dbef8-0f07-4a03-8bec-575095c52cab.json b/src/enm/study-NWKI-f88dbef8-0f07-4a03-8bec-575095c52cab.json
new file mode 100644
index 0000000..dc499be
--- /dev/null
+++ b/src/enm/study-NWKI-f88dbef8-0f07-4a03-8bec-575095c52cab.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-f88dbef8-0f07-4a03-8bec-575095c52cab",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-ce7a2667-21e4-3bd2-b1b6-bd8c298e9df4"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn3010087",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
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+ "r_isUsedforClassification": "false",
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+ "result": {
+ "unit": "nm",
+ "loValue": 24.6,
+ "errorValue": 5.3
+ }
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+ ]
+}
diff --git a/src/enm/study-NWKI-f96d66db-233b-4b6f-906f-302f75470d03.json b/src/enm/study-NWKI-f96d66db-233b-4b6f-906f-302f75470d03.json
new file mode 100644
index 0000000..c527736
--- /dev/null
+++ b/src/enm/study-NWKI-f96d66db-233b-4b6f-906f-302f75470d03.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "NWKI-f96d66db-233b-4b6f-906f-302f75470d03",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3fb9be70-8c15-3b78-94e7-5c3c88799818"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
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+ "TESTMAT_FORM": null
+ },
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+ "result": {
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+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-f9da39f2-c4fe-4158-b508-d51ee55e8122.json b/src/enm/study-NWKI-f9da39f2-c4fe-4158-b508-d51ee55e8122.json
new file mode 100644
index 0000000..46bf611
--- /dev/null
+++ b/src/enm/study-NWKI-f9da39f2-c4fe-4158-b508-d51ee55e8122.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-f9da39f2-c4fe-4158-b508-d51ee55e8122",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-9a0a7a86-fd00-3835-9795-a4da7d9d1544"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
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+ },
+ "interpretation": {
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+ "ELEMENT_OR_GROUP": {
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+ "TYPE": {
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+ }
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+ "unit": null,
+ "textValue": "Fe3O4"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
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+ "COATING_DESCRIPTION": {
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+ "loValue": "CLIO-2DCY7"
+ },
+ "DESCRIPTION": {
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+ "TYPE": {
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+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Cross-2Dlinked_dextran"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-fa7823ae-a58c-4fe5-82c5-cc4d9d952d9b.json b/src/enm/study-NWKI-fa7823ae-a58c-4fe5-82c5-cc4d9d952d9b.json
new file mode 100644
index 0000000..b105b51
--- /dev/null
+++ b/src/enm/study-NWKI-fa7823ae-a58c-4fe5-82c5-cc4d9d952d9b.json
@@ -0,0 +1,61 @@
+{
+ "uuid": "NWKI-fa7823ae-a58c-4fe5-82c5-cc4d9d952d9b",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-d39efcf3-d871-34c2-ac1c-b48f35bde877"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
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+ },
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+ "r_purposeFlag": null,
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+ "endpoint": "ZETA POTENTIAL",
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+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -39,
+ "errorValue": 4.98
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-fa9d23f2-583d-433a-8e54-b769125b6eac.json b/src/enm/study-NWKI-fa9d23f2-583d-433a-8e54-b769125b6eac.json
new file mode 100644
index 0000000..9ad215b
--- /dev/null
+++ b/src/enm/study-NWKI-fa9d23f2-583d-433a-8e54-b769125b6eac.json
@@ -0,0 +1,60 @@
+{
+ "uuid": "NWKI-fa9d23f2-583d-433a-8e54-b769125b6eac",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-f9f316e8-e8a9-37f9-877f-86519b3af20e"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
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+ "Method details": null,
+ "SAMPLING": null,
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+ "Type of method": null
+ },
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+ },
+ "interpretation": {
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+ "effects": [
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+ "pH": null
+ },
+ "result": {
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+ "loValue": -9.46
+ }
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+}
diff --git a/src/enm/study-NWKI-fb0daa9b-a135-4e67-80bb-58735b271757.json b/src/enm/study-NWKI-fb0daa9b-a135-4e67-80bb-58735b271757.json
new file mode 100644
index 0000000..628652a
--- /dev/null
+++ b/src/enm/study-NWKI-fb0daa9b-a135-4e67-80bb-58735b271757.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-fb0daa9b-a135-4e67-80bb-58735b271757",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-6b07ffd5-b573-3889-a64c-ae7cc99ff977"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": -60,
+ "upQualifier": "<=",
+ "upValue": 45
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-fc270c92-d071-4d31-b421-6639903b6777.json b/src/enm/study-NWKI-fc270c92-d071-4d31-b421-6639903b6777.json
new file mode 100644
index 0000000..4af707d
--- /dev/null
+++ b/src/enm/study-NWKI-fc270c92-d071-4d31-b421-6639903b6777.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-fc270c92-d071-4d31-b421-6639903b6777",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 6.25,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-fc688bd6-96d8-4219-a59a-2b95903bea30.json b/src/enm/study-NWKI-fc688bd6-96d8-4219-a59a-2b95903bea30.json
new file mode 100644
index 0000000..9fa4517
--- /dev/null
+++ b/src/enm/study-NWKI-fc688bd6-96d8-4219-a59a-2b95903bea30.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-fc688bd6-96d8-4219-a59a-2b95903bea30",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-a28e83ea-54da-3391-9bca-4a8891680403"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Hydrodynamic size",
+ "guideline": [
+ "DLS"
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "Method type": "DLS",
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "MASS MEDIAN AERODYNAMIC DIAMETER",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 105,
+ "errorValue": 26
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-fc6a8459-0f8c-4910-8e68-1628be59ff93.json b/src/enm/study-NWKI-fc6a8459-0f8c-4910-8e68-1628be59ff93.json
new file mode 100644
index 0000000..cf70775
--- /dev/null
+++ b/src/enm/study-NWKI-fc6a8459-0f8c-4910-8e68-1628be59ff93.json
@@ -0,0 +1,62 @@
+{
+ "uuid": "NWKI-fc6a8459-0f8c-4910-8e68-1628be59ff93",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-cd7cf8fc-ebd1-3b60-827c-aa33e4d5d433"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nl0730155",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": {
+ "loValue": 6.5
+ }
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -53.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-fc98e120-6aeb-496f-ae14-dafbad45794a.json b/src/enm/study-NWKI-fc98e120-6aeb-496f-ae14-dafbad45794a.json
new file mode 100644
index 0000000..371d87d
--- /dev/null
+++ b/src/enm/study-NWKI-fc98e120-6aeb-496f-ae14-dafbad45794a.json
@@ -0,0 +1,92 @@
+{
+ "uuid": "NWKI-fc98e120-6aeb-496f-ae14-dafbad45794a",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-17c74ed1-b289-3ca1-8477-390a588cb28c"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SURFACE_CHEMISTRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "4.30 Nanomaterial surface chemistry"
+ },
+ "endpoint": "Unknown",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": null,
+ "DESCRIPTION": null,
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " ",
+ "loValue": "Fe2O3"
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "CORE"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Fe2O3"
+ }
+ },
+ {
+ "endpoint": "ATOMIC COMPOSITION",
+ "conditions": {
+ "COATING_DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PVA-2DPEG"
+ },
+ "DESCRIPTION": {
+ "loQualifier": " ",
+ "loValue": "PEG"
+ },
+ "ELEMENT_OR_GROUP": {
+ "loQualifier": " "
+ },
+ "Remark": null,
+ "TYPE": {
+ "loQualifier": " ",
+ "loValue": "COATING"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "PEG"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-fd6b8b11-9ff1-4d65-be4b-ff9a0f15245f.json b/src/enm/study-NWKI-fd6b8b11-9ff1-4d65-be4b-ff9a0f15245f.json
new file mode 100644
index 0000000..0be1ebb
--- /dev/null
+++ b/src/enm/study-NWKI-fd6b8b11-9ff1-4d65-be4b-ff9a0f15245f.json
@@ -0,0 +1,58 @@
+{
+ "uuid": "NWKI-fd6b8b11-9ff1-4d65-be4b-ff9a0f15245f",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e4dab3d9-2699-3a0b-9e9c-f257088142cc"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1002/smll.201002366",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Toxicity Classifier",
+ "guideline": [
+ "PI uptake assay"
+ ]
+ },
+ "parameters": {
+ "Cell line": "BEAS-2B",
+ "Method type": "PI uptake assay"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Non-toxic"
+ },
+ "effects": [
+ {
+ "endpoint": "Toxicity Classifier",
+ "conditions": {
+ "Doses/concentrations": {
+ "loValue": 0.375,
+ "unit": "mg/L"
+ }
+ },
+ "result": {
+ "unit": null,
+ "textValue": "Non-toxic"
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-fda09e56-a29d-43ed-9863-8c0f8cbe0261.json b/src/enm/study-NWKI-fda09e56-a29d-43ed-9863-8c0f8cbe0261.json
new file mode 100644
index 0000000..0657cb5
--- /dev/null
+++ b/src/enm/study-NWKI-fda09e56-a29d-43ed-9863-8c0f8cbe0261.json
@@ -0,0 +1,52 @@
+{
+ "uuid": "NWKI-fda09e56-a29d-43ed-9863-8c0f8cbe0261",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e93603a1-8e0d-372a-8acf-48533b86ecb5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/es051043o",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "UNKNOWN_TOXICITY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0000015",
+ "title": "7.99 Toxicity (other)"
+ },
+ "endpoint": "Concentration in culture medium",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Concentration_in_culture_medium",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/g",
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ff0b4348-41cb-40e4-8d13-f8d63fd01973.json b/src/enm/study-NWKI-ff0b4348-41cb-40e4-8d13-f8d63fd01973.json
new file mode 100644
index 0000000..b35f333
--- /dev/null
+++ b/src/enm/study-NWKI-ff0b4348-41cb-40e4-8d13-f8d63fd01973.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-ff0b4348-41cb-40e4-8d13-f8d63fd01973",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-80f9ab46-f8fe-36de-9335-17c9d1dbdba5"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.3109/17435390.2015.1017022",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Diameter",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Diameter",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "μm",
+ "loValue": 1.1,
+ "errorValue": 0.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ff65f97b-b115-4b5e-982e-66757a1be5ef.json b/src/enm/study-NWKI-ff65f97b-b115-4b5e-982e-66757a1be5ef.json
new file mode 100644
index 0000000..51cb2c0
--- /dev/null
+++ b/src/enm/study-NWKI-ff65f97b-b115-4b5e-982e-66757a1be5ef.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "NWKI-ff65f97b-b115-4b5e-982e-66757a1be5ef",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-3e42f6e5-635a-3f1e-a51a-39ce26751ec9"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1038/nnano.2011.10",
+ "year": "2011",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "Log Reciprocal EC50",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "Cell line": "Escherichia coli cells"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "Log_Reciprocal_EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 2.82
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ff7e7c54-4e86-462d-b849-1ca11d72beb9.json b/src/enm/study-NWKI-ff7e7c54-4e86-462d-b849-1ca11d72beb9.json
new file mode 100644
index 0000000..28f4ea2
--- /dev/null
+++ b/src/enm/study-NWKI-ff7e7c54-4e86-462d-b849-1ca11d72beb9.json
@@ -0,0 +1,59 @@
+{
+ "uuid": "NWKI-ff7e7c54-4e86-462d-b849-1ca11d72beb9",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-c8d9772c-e50e-3c71-986c-e45692150d71"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1073/pnas.0802878105",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Primary Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": 20,
+ "upQualifier": "<=",
+ "upValue": 60
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ff824497-26e7-4518-af8a-3db0dbd9caf7.json b/src/enm/study-NWKI-ff824497-26e7-4518-af8a-3db0dbd9caf7.json
new file mode 100644
index 0000000..f7d8945
--- /dev/null
+++ b/src/enm/study-NWKI-ff824497-26e7-4518-af8a-3db0dbd9caf7.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "NWKI-ff824497-26e7-4518-af8a-3db0dbd9caf7",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-21dbebfb-695f-3ff4-b7a4-bead2b52cf13"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": null,
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "Zeta Potential",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DATA_GATHERING_INSTRUMENTS": null,
+ "Method details": null,
+ "SAMPLING": null,
+ "TESTMAT_FORM": null,
+ "Type of method": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ "MEDIUM": null,
+ "Remark": null,
+ "pH": null
+ },
+ "result": {
+ "unit": "nm",
+ "loQualifier": ">=",
+ "loValue": -45,
+ "upQualifier": "<=",
+ "upValue": 55
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-NWKI-ff8b50e6-08e4-4741-a71a-e37ccd013707.json b/src/enm/study-NWKI-ff8b50e6-08e4-4741-a71a-e37ccd013707.json
new file mode 100644
index 0000000..fce9b5a
--- /dev/null
+++ b/src/enm/study-NWKI-ff8b50e6-08e4-4741-a71a-e37ccd013707.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "NWKI-ff8b50e6-08e4-4741-a71a-e37ccd013707",
+ "owner": {
+ "substance": {
+ "uuid": "NWKI-e7bdb2a3-0b3f-3a38-8d6b-1babc6d92da1"
+ },
+ "company": {
+ "uuid": "NWKI-9f4e86d0-c85d-3e83-8249-a856659087da",
+ "name": "NanoWiki"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1021/nn2021056",
+ "year": "0",
+ "owner": "NanoWiki"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "Particle Size",
+ "guideline": [
+ ""
+ ]
+ },
+ "parameters": {
+ "DISTRIBUTION_TYPE": null,
+ "TESTMAT_FORM": null
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PARTICLE SIZE",
+ "conditions": {
+ "Remark": null,
+ "SEQ_NUM": null
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 15.5,
+ "errorValue": 4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-001d8891-b389-444b-83a7-c3432b81624c.json b/src/enm/study-XLSX-001d8891-b389-444b-83a7-c3432b81624c.json
new file mode 100644
index 0000000..6d9dcb3
--- /dev/null
+++ b/src/enm/study-XLSX-001d8891-b389-444b-83a7-c3432b81624c.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-001d8891-b389-444b-83a7-c3432b81624c",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-295d65e6-0d6e-3987-a67f-e4482fa28c71"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "099",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "099",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "round"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-00f20ed0-d6be-485d-be1f-0fd5cfea6f45.json b/src/enm/study-XLSX-00f20ed0-d6be-485d-be1f-0fd5cfea6f45.json
new file mode 100644
index 0000000..3536888
--- /dev/null
+++ b/src/enm/study-XLSX-00f20ed0-d6be-485d-be1f-0fd5cfea6f45.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-00f20ed0-d6be-485d-be1f-0fd5cfea6f45",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-38666e26-8f8e-37a4-b97c-728a1e5aa0f2"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "038",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "038",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ },
+ "result": {
+ "unit": "(m2/g)",
+ "loValue": 226.4
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-012fa9ed-275d-43bf-996d-20ee50308991.json b/src/enm/study-XLSX-012fa9ed-275d-43bf-996d-20ee50308991.json
new file mode 100644
index 0000000..c65c5aa
--- /dev/null
+++ b/src/enm/study-XLSX-012fa9ed-275d-43bf-996d-20ee50308991.json
@@ -0,0 +1,1016 @@
+{
+ "uuid": "XLSX-012fa9ed-275d-43bf-996d-20ee50308991",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-aacdfad8-f3d3-39f2-b662-0d8084e283ef"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "Cell viability - cell membrane damage: Lactate dehydrogenase assay (LDH) (CytoTox 96® Non-radioactive cytotoxicity assay - Promega, G1780) ",
+ "guideline": [
+ "Cytotoxicity using human monocyte-derived macrophages (HMDM)"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "N",
+ "CLO_0000031": "HMDM",
+ "CLO_0000031 EFO_0004443": "Karolinska University Hospital, Stockholm, Sweden - buffy coats from healthy adult blood donors ",
+ "Cell culture conditions - Serum": "FBS (Gibco, 10500) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": "0,05%",
+ "Cell line/Type - Full name": "Primary human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "Y",
+ "NPO_1961": "Y",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, R0833)"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 97.542
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.65
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.321
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 82.461
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 68.18
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 58.725
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 39.835
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 98.295
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 97.724
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 93.735
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 64.729
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 53.187
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 43.117
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 99.92
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 91.437
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "Concentration": {
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+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 82.094
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 56.049
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 25.874
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 23.828
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 28.389
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 88.264
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+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 5,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "unit": "h"
+ }
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+ "result": {
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 25,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 61.029
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+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
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+ "result": {
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+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 75,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
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+ "result": {
+ "unit": "%",
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+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "unit": "h"
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+ },
+ "result": {
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+ "loValue": 28.98
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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index 0000000..dc51167
--- /dev/null
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+{
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index 0000000..25638f2
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+++ b/src/enm/study-XLSX-05e344f8-3e92-4433-b1df-25613c1b2284.json
@@ -0,0 +1,75 @@
+{
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+++ b/src/enm/study-XLSX-075a1a1e-f09b-463e-ace6-453b2109941a.json
@@ -0,0 +1,75 @@
+{
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+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
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+ "WST-1"
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diff --git a/src/enm/study-XLSX-0768a016-0b68-4992-a896-ce2a9dadca36.json b/src/enm/study-XLSX-0768a016-0b68-4992-a896-ce2a9dadca36.json
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index 0000000..72d091b
--- /dev/null
+++ b/src/enm/study-XLSX-0768a016-0b68-4992-a896-ce2a9dadca36.json
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+{
+ "uuid": "XLSX-0768a016-0b68-4992-a896-ce2a9dadca36",
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+ "name": "FP7 MARINA"
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+ "year": "2015",
+ "owner": "P32 - KI"
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+ "topcategory": "TOX",
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+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "Cell viability - cell membrane damage: Lactate dehydrogenase assay (LDH) (CytoTox 96® Non-radioactive cytotoxicity assay - Promega, G1780) ",
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+ "unit": "%",
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+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 1,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.376
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 5,
+ "unit": "µg/ml"
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+ "unit": "h"
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+ },
+ {
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+ "loValue": 10,
+ "unit": "µg/ml"
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+ "loValue": 6,
+ "unit": "h"
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+ },
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+ "unit": "%",
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+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 25,
+ "unit": "µg/ml"
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+ "loValue": 6,
+ "unit": "h"
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+ },
+ {
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ },
+ {
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+ "unit": "µg/ml"
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ "unit": "h"
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+ "unit": "µg/ml"
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+ {
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+ "unit": "h"
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+ }
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+ {
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+ "unit": "h"
+ }
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "unit": "µg/ml"
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 43.694
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-07ccb8b4-5cc7-4b87-8627-c6e3c1833de3.json b/src/enm/study-XLSX-07ccb8b4-5cc7-4b87-8627-c6e3c1833de3.json
new file mode 100644
index 0000000..144eccf
--- /dev/null
+++ b/src/enm/study-XLSX-07ccb8b4-5cc7-4b87-8627-c6e3c1833de3.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-07ccb8b4-5cc7-4b87-8627-c6e3c1833de3",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-3ff81e94-3d5d-3e58-a761-b0bd7c94de3b"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "107",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "107",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 87
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-0833c070-e1d1-42cf-90da-eda8083970fa.json b/src/enm/study-XLSX-0833c070-e1d1-42cf-90da-eda8083970fa.json
new file mode 100644
index 0000000..6e89101
--- /dev/null
+++ b/src/enm/study-XLSX-0833c070-e1d1-42cf-90da-eda8083970fa.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "XLSX-0833c070-e1d1-42cf-90da-eda8083970fa",
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+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "185",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "185",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "16HBE",
+ "Dispersion protocol": "Tip",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.05
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 211.139
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 350.807
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 5.587
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-1005b3f5-639d-48e8-8f4e-962006996f96.json b/src/enm/study-XLSX-1005b3f5-639d-48e8-8f4e-962006996f96.json
new file mode 100644
index 0000000..90dbe4d
--- /dev/null
+++ b/src/enm/study-XLSX-1005b3f5-639d-48e8-8f4e-962006996f96.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-1005b3f5-639d-48e8-8f4e-962006996f96",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-7677801c-4895-3ffd-807a-832c589341df"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "151",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "151",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "elongated and rounded"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-10528600-01ff-4fcb-8ffd-eb1c14622464.json b/src/enm/study-XLSX-10528600-01ff-4fcb-8ffd-eb1c14622464.json
new file mode 100644
index 0000000..2a4c507
--- /dev/null
+++ b/src/enm/study-XLSX-10528600-01ff-4fcb-8ffd-eb1c14622464.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-10528600-01ff-4fcb-8ffd-eb1c14622464",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-a0d9ab63-ee03-3224-984a-4bd276e3ea3a"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "143",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "143",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-11423ba7-45fe-47f7-aa2f-1021853503a8.json b/src/enm/study-XLSX-11423ba7-45fe-47f7-aa2f-1021853503a8.json
new file mode 100644
index 0000000..46394d0
--- /dev/null
+++ b/src/enm/study-XLSX-11423ba7-45fe-47f7-aa2f-1021853503a8.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-11423ba7-45fe-47f7-aa2f-1021853503a8",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-acb82e6d-63d6-3cf4-a796-a281b1ba835f"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "012",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "012",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Bath"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 44.8
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 44.8
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 500
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-115502dc-3a59-4d3c-b0e6-14ae7f7dd05e.json b/src/enm/study-XLSX-115502dc-3a59-4d3c-b0e6-14ae7f7dd05e.json
new file mode 100644
index 0000000..69cb005
--- /dev/null
+++ b/src/enm/study-XLSX-115502dc-3a59-4d3c-b0e6-14ae7f7dd05e.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "XLSX-115502dc-3a59-4d3c-b0e6-14ae7f7dd05e",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d6285533-0204-3884-a3d8-1dffdcde6324"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "075",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "075",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Bath"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 25.08
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 25.08
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-116c7102-9677-4acb-9923-e13a326e0848.json b/src/enm/study-XLSX-116c7102-9677-4acb-9923-e13a326e0848.json
new file mode 100644
index 0000000..28c31d8
--- /dev/null
+++ b/src/enm/study-XLSX-116c7102-9677-4acb-9923-e13a326e0848.json
@@ -0,0 +1,696 @@
+{
+ "uuid": "XLSX-116c7102-9677-4acb-9923-e13a326e0848",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-b4e4a8e9-6d27-3218-a243-7aa30560adb1"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "",
+ "guideline": [
+ "ELISA / TNF-α release in culture medium"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "Y",
+ "CLO_0000031": "HMDM (primary cells)",
+ "CLO_0000031 EFO_0004443": "ATCC",
+ "Cell culture conditions - Serum": "FBS (Gibco/413105K) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": 0.1,
+ "Cell line/Type - Full name": "human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "N",
+ "NPO_1961": "N",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, RNBB2729 "
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 19.209
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 51.34
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 54.146
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 54.248
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 51.382
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 40.765
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 21.658
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 8.806
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 17.204
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 25.185
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 38.635
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 53.932
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 58.479
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 49.172
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 28.59
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 11.051
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 4.515
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 5.748
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 17.559
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 63.942
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 13.506
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 7.371
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 5.037
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 4.846
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 16.168
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 25.371
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 42.205
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 87.953
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 37.918
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 14.972
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 9.695
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 8.52
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-11ef2efa-2bf7-48b3-8c89-e3b993f25ff8.json b/src/enm/study-XLSX-11ef2efa-2bf7-48b3-8c89-e3b993f25ff8.json
new file mode 100644
index 0000000..f6394e6
--- /dev/null
+++ b/src/enm/study-XLSX-11ef2efa-2bf7-48b3-8c89-e3b993f25ff8.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-11ef2efa-2bf7-48b3-8c89-e3b993f25ff8",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-56c58705-05c6-304f-bb42-a3a328e06319"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "182",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "182",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Mainly 2 euhedral morphologies: aspect ratio of 1 (20–250 nm and 400 nm) and 2:7,5 (50-350 nm)"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.68
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-124615d0-026f-447e-989d-130ae65fc29a.json b/src/enm/study-XLSX-124615d0-026f-447e-989d-130ae65fc29a.json
new file mode 100644
index 0000000..f872a35
--- /dev/null
+++ b/src/enm/study-XLSX-124615d0-026f-447e-989d-130ae65fc29a.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "XLSX-124615d0-026f-447e-989d-130ae65fc29a",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-7d5a7a1b-5069-3256-b796-2361afcf3bfe"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "032",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "032",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Vortexing"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 11
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 846
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-1510c9ea-dae8-44cd-a1f6-d15ce9cfb6aa.json b/src/enm/study-XLSX-1510c9ea-dae8-44cd-a1f6-d15ce9cfb6aa.json
new file mode 100644
index 0000000..b9a0217
--- /dev/null
+++ b/src/enm/study-XLSX-1510c9ea-dae8-44cd-a1f6-d15ce9cfb6aa.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-1510c9ea-dae8-44cd-a1f6-d15ce9cfb6aa",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-190fb54d-9b65-3d58-b65e-b3aae9a1f182"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "154",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "154",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Vortexing"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 10
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 1338
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-151a3b5f-21cc-4eae-a99e-5a3776271a9f.json b/src/enm/study-XLSX-151a3b5f-21cc-4eae-a99e-5a3776271a9f.json
new file mode 100644
index 0000000..a2fe805
--- /dev/null
+++ b/src/enm/study-XLSX-151a3b5f-21cc-4eae-a99e-5a3776271a9f.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-151a3b5f-21cc-4eae-a99e-5a3776271a9f",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-ade46bc8-d87f-3f9b-afd0-11ca32e5caeb"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "178",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "178",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Bath"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 101
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 170
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 180
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-15394a5e-dc9c-4109-a703-48bfece9354e.json b/src/enm/study-XLSX-15394a5e-dc9c-4109-a703-48bfece9354e.json
new file mode 100644
index 0000000..3637bf3
--- /dev/null
+++ b/src/enm/study-XLSX-15394a5e-dc9c-4109-a703-48bfece9354e.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-15394a5e-dc9c-4109-a703-48bfece9354e",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-00cd0ac9-9adc-38a5-9520-89ddd591f75f"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "192",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "192",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-15ffea9f-f9f9-4601-bf6a-4176fd20c40d.json b/src/enm/study-XLSX-15ffea9f-f9f9-4601-bf6a-4176fd20c40d.json
new file mode 100644
index 0000000..4a4220c
--- /dev/null
+++ b/src/enm/study-XLSX-15ffea9f-f9f9-4601-bf6a-4176fd20c40d.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-15ffea9f-f9f9-4601-bf6a-4176fd20c40d",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d4f2714a-a7f6-305a-af41-18d8129fef13"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "184",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "184",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ },
+ "result": {
+ "unit": "m2/g",
+ "loValue": 77.992
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-166efb6a-eae4-481e-810b-57e1a6712b78.json b/src/enm/study-XLSX-166efb6a-eae4-481e-810b-57e1a6712b78.json
new file mode 100644
index 0000000..7a7c325
--- /dev/null
+++ b/src/enm/study-XLSX-166efb6a-eae4-481e-810b-57e1a6712b78.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-166efb6a-eae4-481e-810b-57e1a6712b78",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d3a9ce39-6c15-3e4b-a5ce-5ea23e45ff16"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "111",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "111",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "NRK-52E",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 101.589
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 111.998
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.416
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-16b44d12-07d4-4c81-97f8-e5068e683d8a.json b/src/enm/study-XLSX-16b44d12-07d4-4c81-97f8-e5068e683d8a.json
new file mode 100644
index 0000000..3bb068e
--- /dev/null
+++ b/src/enm/study-XLSX-16b44d12-07d4-4c81-97f8-e5068e683d8a.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-16b44d12-07d4-4c81-97f8-e5068e683d8a",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-ad0a7571-a887-3611-a508-f32ad71f20be"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "079",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0010001_SECTION",
+ "term": "http://purl.bioontology.org/ontology/bao#BAO_0010001",
+ "title": "BAO_0010001 ATP Assay"
+ },
+ "endpoint": "079",
+ "guideline": [
+ "ATP"
+ ]
+ },
+ "parameters": {
+ "Cell line": "U-87 MG",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 1.732
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 4.308
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.103
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-178be221-af2d-46a4-a9c4-6cd303bf0f89.json b/src/enm/study-XLSX-178be221-af2d-46a4-a9c4-6cd303bf0f89.json
new file mode 100644
index 0000000..3d2997b
--- /dev/null
+++ b/src/enm/study-XLSX-178be221-af2d-46a4-a9c4-6cd303bf0f89.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-178be221-af2d-46a4-a9c4-6cd303bf0f89",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-2acfa382-5109-3e49-9fd4-ef8d139be4b2"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "101",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "101",
+ "guideline": [
+ "WST-1"
+ ]
+ },
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index 0000000..a9d1517
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+{
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+ "endpoint": "Cell viability - cell membrane damage: Lactate dehydrogenase assay (LDH) (CytoTox 96® Non-radioactive cytotoxicity assay - Promega, G1780) ",
+ "guideline": [
+ "Cytotoxicity using human monocyte-derived macrophages (HMDM)"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "N",
+ "CLO_0000031": "HMDM",
+ "CLO_0000031 EFO_0004443": "Karolinska University Hospital, Stockholm, Sweden - buffy coats from healthy adult blood donors ",
+ "Cell culture conditions - Serum": "FBS (Gibco, 10500) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": "0,05%",
+ "Cell line/Type - Full name": "Primary human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "Y",
+ "NPO_1961": "Y",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, R0833)"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.244
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 97.04
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 92.331
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 92.2
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.548
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 91.351
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 88.663
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100.657
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 102.033
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 102.058
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 101.331
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 103.58
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 103.111
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 102.116
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 106.119
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 99.162
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 101.619
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 93.146
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 91.801
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 98.457
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 78.147
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 85.847
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 84.564
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 68.466
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 69.795
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 71.551
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 42.512
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 58.861
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 95.042
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 99.02
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 77.547
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 73.485
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 64.706
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 72.679
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 56.168
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 109.581
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 116.075
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 95.767
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 90.067
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100.967
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.509
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.421
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-29a4590d-58e8-4505-af16-6b3317e95381.json b/src/enm/study-XLSX-29a4590d-58e8-4505-af16-6b3317e95381.json
new file mode 100644
index 0000000..7fb8791
--- /dev/null
+++ b/src/enm/study-XLSX-29a4590d-58e8-4505-af16-6b3317e95381.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-29a4590d-58e8-4505-af16-6b3317e95381",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-a1b25bf2-6046-3c16-ba1c-3efb11b5a4d6"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
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index 0000000..c54cacc
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index 0000000..be087f7
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+{
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index 0000000..75b738d
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+{
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+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 8.032
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 9.734
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.068
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-301fd1d5-cd81-4641-917c-7628be4bf734.json b/src/enm/study-XLSX-301fd1d5-cd81-4641-917c-7628be4bf734.json
new file mode 100644
index 0000000..dd021cd
--- /dev/null
+++ b/src/enm/study-XLSX-301fd1d5-cd81-4641-917c-7628be4bf734.json
@@ -0,0 +1,696 @@
+{
+ "uuid": "XLSX-301fd1d5-cd81-4641-917c-7628be4bf734",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-93b2da85-fc0c-315f-8d3b-77f1a7776fb4"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "",
+ "guideline": [
+ "ELISA / TNF-α release in culture medium"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "Y",
+ "CLO_0000031": "HMDM (primary cells)",
+ "CLO_0000031 EFO_0004443": "ATCC",
+ "Cell culture conditions - Serum": "FBS (Gibco/413105K) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": 0.1,
+ "Cell line/Type - Full name": "human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "N",
+ "NPO_1961": "N",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, RNBB2729 "
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 3.092
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 9.627
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 3.7
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 12.022
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 13.495
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 11.939
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 9.904
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 9.839
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 0.874
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.035
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.071
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.04
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.536
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.801
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 6.024
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 3.218
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 9.147
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 13.019
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 12.83
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 12.336
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 18.473
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 25.681
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 22.385
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 18.916
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 21.04
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 29.97
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 26.508
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 30.14
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 43.317
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 44.152
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 51.261
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 63.261
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-3064e0bc-9082-44a7-a4bd-3add51baca08.json b/src/enm/study-XLSX-3064e0bc-9082-44a7-a4bd-3add51baca08.json
new file mode 100644
index 0000000..d531eea
--- /dev/null
+++ b/src/enm/study-XLSX-3064e0bc-9082-44a7-a4bd-3add51baca08.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-3064e0bc-9082-44a7-a4bd-3add51baca08",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d3a9ce39-6c15-3e4b-a5ce-5ea23e45ff16"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "113",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "113",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "subangular to rounded"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.567
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-30e50959-2e9e-4681-8da4-fc1ab241354c.json b/src/enm/study-XLSX-30e50959-2e9e-4681-8da4-fc1ab241354c.json
new file mode 100644
index 0000000..2e4cca6
--- /dev/null
+++ b/src/enm/study-XLSX-30e50959-2e9e-4681-8da4-fc1ab241354c.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-30e50959-2e9e-4681-8da4-fc1ab241354c",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-673c8355-a823-3bf2-a319-0d8af43e4d90"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "144",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "144",
+ "guideline": [
+ "LDH"
+ ]
+ },
+ "parameters": {
+ "Cell line": "A549",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 132.853
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 151.197
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.734
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-3161393e-b37f-4ff5-a4fd-359e79dc7cef.json b/src/enm/study-XLSX-3161393e-b37f-4ff5-a4fd-359e79dc7cef.json
new file mode 100644
index 0000000..253f17c
--- /dev/null
+++ b/src/enm/study-XLSX-3161393e-b37f-4ff5-a4fd-359e79dc7cef.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-3161393e-b37f-4ff5-a4fd-359e79dc7cef",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-0bfa2e41-c6b6-3cbf-8a1e-73bf006768ab"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
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index 0000000..9d38dc9
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+ "SPECIFIC SURFACE AREA"
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index 0000000..ed7169e
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+{
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index 0000000..c97ea97
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+{
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index 0000000..45c240b
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index 0000000..94e35ea
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+++ b/src/enm/study-XLSX-40fba3c0-4cba-47d5-a250-c23a2297fa4c.json
@@ -0,0 +1,72 @@
+{
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index 0000000..c6e9e78
--- /dev/null
+++ b/src/enm/study-XLSX-41595fe0-3c7b-4725-b209-f0267aa83da7.json
@@ -0,0 +1,75 @@
+{
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+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
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index 0000000..79fb7a2
--- /dev/null
+++ b/src/enm/study-XLSX-41d9609b-1d68-442f-9896-03cc648e1240.json
@@ -0,0 +1,53 @@
+{
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+ "title": "4.27 Nanomaterial aspect ratio/shape"
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+ "endpoint": "022",
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index 0000000..6757584
--- /dev/null
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+{
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+ "title": "4.28 Nanomaterial specific surface area"
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+ "endpoint": "031",
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index 0000000..fb98c70
--- /dev/null
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+{
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+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
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new file mode 100644
index 0000000..3310d09
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+{
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+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "027",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "027",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "sphere"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-45aeb6a7-b132-404a-8702-f5988da7f94a.json b/src/enm/study-XLSX-45aeb6a7-b132-404a-8702-f5988da7f94a.json
new file mode 100644
index 0000000..50bb303
--- /dev/null
+++ b/src/enm/study-XLSX-45aeb6a7-b132-404a-8702-f5988da7f94a.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-45aeb6a7-b132-404a-8702-f5988da7f94a",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-7d5a7a1b-5069-3256-b796-2361afcf3bfe"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "032",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "032",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Irregular entangled kinked and mostly bent "
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 79
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-45bd15a8-3413-4050-ae56-b76fd52cd676.json b/src/enm/study-XLSX-45bd15a8-3413-4050-ae56-b76fd52cd676.json
new file mode 100644
index 0000000..d840a61
--- /dev/null
+++ b/src/enm/study-XLSX-45bd15a8-3413-4050-ae56-b76fd52cd676.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-45bd15a8-3413-4050-ae56-b76fd52cd676",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-bbff7bfc-273b-3dfb-be71-5afb33113e53"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "022",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "022",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ },
+ "result": {
+ "unit": "m2/g",
+ "loValue": 7.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-47c449e6-57f0-416d-8b3b-bdf758f07c90.json b/src/enm/study-XLSX-47c449e6-57f0-416d-8b3b-bdf758f07c90.json
new file mode 100644
index 0000000..9252a40
--- /dev/null
+++ b/src/enm/study-XLSX-47c449e6-57f0-416d-8b3b-bdf758f07c90.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-47c449e6-57f0-416d-8b3b-bdf758f07c90",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-de76fc02-ef1f-310a-b61f-6aab5b586412"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "118",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "118",
+ "guideline": [
+ "LDH"
+ ]
+ },
+ "parameters": {
+ "Cell line": "THP-1 macrophage",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
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+ "result": {
+ "unit": "ug/ml",
+ "loValue": 97.777
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 120.819
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.922
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4983675e-d2fd-4212-bc78-f424507604c4.json b/src/enm/study-XLSX-4983675e-d2fd-4212-bc78-f424507604c4.json
new file mode 100644
index 0000000..c850523
--- /dev/null
+++ b/src/enm/study-XLSX-4983675e-d2fd-4212-bc78-f424507604c4.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "XLSX-4983675e-d2fd-4212-bc78-f424507604c4",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-2aef353b-440f-32a7-8447-1974997a69a8"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "190",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "190",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
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+ "result": {
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+ "loQualifier": ">=",
+ "loValue": 26.3,
+ "upQualifier": "<=",
+ "upValue": 28.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4a8aca48-c975-468b-9be8-03c6e735baa7.json b/src/enm/study-XLSX-4a8aca48-c975-468b-9be8-03c6e735baa7.json
new file mode 100644
index 0000000..b8692b4
--- /dev/null
+++ b/src/enm/study-XLSX-4a8aca48-c975-468b-9be8-03c6e735baa7.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-4a8aca48-c975-468b-9be8-03c6e735baa7",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5d7807f7-a13b-392f-88af-fe7885a67502"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "170",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "170",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Bath"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
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+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
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+ "result": {
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+ "loValue": 106
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 178
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 160
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4b3b96a6-c670-4ed6-90b8-2afe609f597f.json b/src/enm/study-XLSX-4b3b96a6-c670-4ed6-90b8-2afe609f597f.json
new file mode 100644
index 0000000..25712f6
--- /dev/null
+++ b/src/enm/study-XLSX-4b3b96a6-c670-4ed6-90b8-2afe609f597f.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-4b3b96a6-c670-4ed6-90b8-2afe609f597f",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d7934c3e-9eac-34bc-8c60-4cf0c46e92a3"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "008",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "008",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Bath"
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_studyResultType": "experimental result",
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
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+ "result": {
+ "unit": "nm",
+ "loValue": 18.8
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 18.8
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 35
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4b73086a-515b-40b6-8e23-358337ba64f2.json b/src/enm/study-XLSX-4b73086a-515b-40b6-8e23-358337ba64f2.json
new file mode 100644
index 0000000..f971bef
--- /dev/null
+++ b/src/enm/study-XLSX-4b73086a-515b-40b6-8e23-358337ba64f2.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-4b73086a-515b-40b6-8e23-358337ba64f2",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-aa7e2fd6-c054-35ed-a9d9-1f40c1d179a3"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "138",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "138",
+ "guideline": [
+ "LDH"
+ ]
+ },
+ "parameters": {
+ "Cell line": "NRK-52E",
+ "Dispersion protocol": "Tip",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
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+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 27626.677
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 155892.087
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 5130.616
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4be76f8a-a3f8-4a4e-99f1-6b0cb81cd1e5.json b/src/enm/study-XLSX-4be76f8a-a3f8-4a4e-99f1-6b0cb81cd1e5.json
new file mode 100644
index 0000000..57feef5
--- /dev/null
+++ b/src/enm/study-XLSX-4be76f8a-a3f8-4a4e-99f1-6b0cb81cd1e5.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-4be76f8a-a3f8-4a4e-99f1-6b0cb81cd1e5",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5e44448d-216f-3b91-891a-a7e1de030a13"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "186",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "186",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -43.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4ce6ad29-3317-407c-8c7b-62a0701762c2.json b/src/enm/study-XLSX-4ce6ad29-3317-407c-8c7b-62a0701762c2.json
new file mode 100644
index 0000000..cc75144
--- /dev/null
+++ b/src/enm/study-XLSX-4ce6ad29-3317-407c-8c7b-62a0701762c2.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-4ce6ad29-3317-407c-8c7b-62a0701762c2",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5efaa24e-6eb5-3f1f-a9f4-680bc92364d6"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "123",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "123",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Stirring"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 17
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 17
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 41.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4cead62b-dda7-4f5f-945f-ceb75c9a2eda.json b/src/enm/study-XLSX-4cead62b-dda7-4f5f-945f-ceb75c9a2eda.json
new file mode 100644
index 0000000..37c9d2c
--- /dev/null
+++ b/src/enm/study-XLSX-4cead62b-dda7-4f5f-945f-ceb75c9a2eda.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-4cead62b-dda7-4f5f-945f-ceb75c9a2eda",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-36cbb933-ec3a-3d8b-b80f-0d5b6e76edc5"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "028",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "028",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "sphere"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4dd12e6c-c554-44e6-8428-732407473c6b.json b/src/enm/study-XLSX-4dd12e6c-c554-44e6-8428-732407473c6b.json
new file mode 100644
index 0000000..55a52a2
--- /dev/null
+++ b/src/enm/study-XLSX-4dd12e6c-c554-44e6-8428-732407473c6b.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-4dd12e6c-c554-44e6-8428-732407473c6b",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-6fac9681-a5c7-337c-9e35-87c04579f0e6"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "083",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "083",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -30
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4de28065-48d6-4388-82dd-ea35142f27f2.json b/src/enm/study-XLSX-4de28065-48d6-4388-82dd-ea35142f27f2.json
new file mode 100644
index 0000000..d25d64f
--- /dev/null
+++ b/src/enm/study-XLSX-4de28065-48d6-4388-82dd-ea35142f27f2.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-4de28065-48d6-4388-82dd-ea35142f27f2",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-00cd0ac9-9adc-38a5-9520-89ddd591f75f"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "192",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "192",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "polyhedral with irregular morphology"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4e10f71e-e821-4cb6-9cb1-ffa7d05a9294.json b/src/enm/study-XLSX-4e10f71e-e821-4cb6-9cb1-ffa7d05a9294.json
new file mode 100644
index 0000000..7e840dd
--- /dev/null
+++ b/src/enm/study-XLSX-4e10f71e-e821-4cb6-9cb1-ffa7d05a9294.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-4e10f71e-e821-4cb6-9cb1-ffa7d05a9294",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5efaa24e-6eb5-3f1f-a9f4-680bc92364d6"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "122",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "122",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "NRK-52E",
+ "Dispersion protocol": "Stirring",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 7.983
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 16.998
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.361
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-4fad36a5-e05a-4e18-9e4d-9dd542742970.json b/src/enm/study-XLSX-4fad36a5-e05a-4e18-9e4d-9dd542742970.json
new file mode 100644
index 0000000..a9baf58
--- /dev/null
+++ b/src/enm/study-XLSX-4fad36a5-e05a-4e18-9e4d-9dd542742970.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-4fad36a5-e05a-4e18-9e4d-9dd542742970",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d6285533-0204-3884-a3d8-1dffdcde6324"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "074",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0010001_SECTION",
+ "term": "http://purl.bioontology.org/ontology/bao#BAO_0010001",
+ "title": "BAO_0010001 ATP Assay"
+ },
+ "endpoint": "074",
+ "guideline": [
+ "ATP"
+ ]
+ },
+ "parameters": {
+ "Cell line": "U-87 MG",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 48,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 90.3
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 295.564
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 8.211
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-502d510d-75f3-4178-ad7b-66d35eca34fc.json b/src/enm/study-XLSX-502d510d-75f3-4178-ad7b-66d35eca34fc.json
new file mode 100644
index 0000000..0943a29
--- /dev/null
+++ b/src/enm/study-XLSX-502d510d-75f3-4178-ad7b-66d35eca34fc.json
@@ -0,0 +1,696 @@
+{
+ "uuid": "XLSX-502d510d-75f3-4178-ad7b-66d35eca34fc",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-fa48e134-54cf-3417-a63a-6f744191cec2"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "",
+ "guideline": [
+ "ELISA / TNF-α release in culture medium"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "Y",
+ "CLO_0000031": "HMDM (primary cells)",
+ "CLO_0000031 EFO_0004443": "ATCC",
+ "Cell culture conditions - Serum": "FBS (Gibco/413105K) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": 0.1,
+ "Cell line/Type - Full name": "human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "N",
+ "NPO_1961": "N",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, RNBB2729 "
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 19.209
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 49.533
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 53.391
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 50.428
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 28.303
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 16.896
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 7.728
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 6.272
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 17.204
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 33.116
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 41.917
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 50.258
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 40.343
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 20.83
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 9.504
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 5.553
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 4.515
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 8.867
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 13.772
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 29.028
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 15.238
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 5.522
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 4.2
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 4.228
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 16.168
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 26.755
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 30.424
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
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+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 61.664
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "Concentration": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "Concentration": {
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+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
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+ "unit": "h"
+ }
+ },
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+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "loValue": 75,
+ "unit": "µg/ml"
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+ "Time point": {
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 7.709
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 7.886
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-503e5833-d2b4-49c6-9f7e-beb12dffa851.json b/src/enm/study-XLSX-503e5833-d2b4-49c6-9f7e-beb12dffa851.json
new file mode 100644
index 0000000..f01ab55
--- /dev/null
+++ b/src/enm/study-XLSX-503e5833-d2b4-49c6-9f7e-beb12dffa851.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-503e5833-d2b4-49c6-9f7e-beb12dffa851",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d6285533-0204-3884-a3d8-1dffdcde6324"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "065",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0010001_SECTION",
+ "term": "http://purl.bioontology.org/ontology/bao#BAO_0010001",
+ "title": "BAO_0010001 ATP Assay"
+ },
+ "endpoint": "065",
+ "guideline": [
+ "ATP"
+ ]
+ },
+ "parameters": {
+ "Cell line": "SK-OV-3",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 1,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 48.037
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 145.919
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 3.915
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-505f7983-f6cc-4965-b267-6bf2ebf5d4ac.json b/src/enm/study-XLSX-505f7983-f6cc-4965-b267-6bf2ebf5d4ac.json
new file mode 100644
index 0000000..996f80f
--- /dev/null
+++ b/src/enm/study-XLSX-505f7983-f6cc-4965-b267-6bf2ebf5d4ac.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-505f7983-f6cc-4965-b267-6bf2ebf5d4ac",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-a44564c5-1458-3e3b-aca7-d63f5221d2a8"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "181",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "181",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "A549",
+ "Dispersion protocol": "Tip",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
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+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 8.755
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 14.497
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.23
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-52342ee4-a212-41f4-919b-4b2657948373.json b/src/enm/study-XLSX-52342ee4-a212-41f4-919b-4b2657948373.json
new file mode 100644
index 0000000..37b93ad
--- /dev/null
+++ b/src/enm/study-XLSX-52342ee4-a212-41f4-919b-4b2657948373.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-52342ee4-a212-41f4-919b-4b2657948373",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-dce22e5a-6ef2-3fd1-b1c8-9ebdb7bd5d2f"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "057",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0010001_SECTION",
+ "term": "http://purl.bioontology.org/ontology/bao#BAO_0010001",
+ "title": "BAO_0010001 ATP Assay"
+ },
+ "endpoint": "057",
+ "guideline": [
+ "ATP"
+ ]
+ },
+ "parameters": {
+ "Cell line": "SK-OV-3",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 72,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
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+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 4.761
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 10.851
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.244
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-53055f0e-f399-401f-8e00-752d041dc2ad.json b/src/enm/study-XLSX-53055f0e-f399-401f-8e00-752d041dc2ad.json
new file mode 100644
index 0000000..076c98e
--- /dev/null
+++ b/src/enm/study-XLSX-53055f0e-f399-401f-8e00-752d041dc2ad.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-53055f0e-f399-401f-8e00-752d041dc2ad",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-0d71a921-0e8d-3f25-8deb-20478b7e884b"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "127",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "127",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Stirring"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 124
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-53347e92-6eda-4e2b-be15-4210fb3bec01.json b/src/enm/study-XLSX-53347e92-6eda-4e2b-be15-4210fb3bec01.json
new file mode 100644
index 0000000..f5f0cf3
--- /dev/null
+++ b/src/enm/study-XLSX-53347e92-6eda-4e2b-be15-4210fb3bec01.json
@@ -0,0 +1,696 @@
+{
+ "uuid": "XLSX-53347e92-6eda-4e2b-be15-4210fb3bec01",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-7011cea0-1011-3f8b-9e8a-b3289fed836a"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "",
+ "guideline": [
+ "ELISA / TNF-α release in culture medium"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "Y",
+ "CLO_0000031": "HMDM (primary cells)",
+ "CLO_0000031 EFO_0004443": "ATCC",
+ "Cell culture conditions - Serum": "FBS (Gibco/413105K) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": 0.1,
+ "Cell line/Type - Full name": "human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "N",
+ "NPO_1961": "N",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, RNBB2729 "
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
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+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "loValue": 1,
+ "unit": "µg/ml"
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "unit": "µg/ml"
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+ }
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+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ }
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+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "loValue": 25,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
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+ "unit": "h"
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+ },
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ {
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ "unit": "µg/ml"
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+ "endpoint": "TNF-α (ng/ml)",
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+ "unit": "µg/ml"
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+ {
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ },
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "unit": "µg/ml"
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+ "unit": "µg/ml"
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
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+ "loValue": 50,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 2",
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+ "unit": "h"
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+ },
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+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "unit": "h"
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+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "loValue": 100,
+ "unit": "µg/ml"
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+ "unit": "h"
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
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+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
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+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.002
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.786
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.57
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.735
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.29
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.206
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 9.502
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 8.808
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 8.957
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 8.306
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 8.244
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 9.507
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 14.416
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 15.438
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-53a8f685-15f3-401d-bfd8-04ba11b01caf.json b/src/enm/study-XLSX-53a8f685-15f3-401d-bfd8-04ba11b01caf.json
new file mode 100644
index 0000000..eef99af
--- /dev/null
+++ b/src/enm/study-XLSX-53a8f685-15f3-401d-bfd8-04ba11b01caf.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-53a8f685-15f3-401d-bfd8-04ba11b01caf",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-f1b0af03-df66-3849-93cc-4ca706c0f751"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "163",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "163",
+ "guideline": [
+ "LDH"
+ ]
+ },
+ "parameters": {
+ "Cell line": "NRK-52E",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 23.412
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 25.849
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.097
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-54374c80-9b0b-422b-b7d6-1b88ff2559d7.json b/src/enm/study-XLSX-54374c80-9b0b-422b-b7d6-1b88ff2559d7.json
new file mode 100644
index 0000000..657cf6f
--- /dev/null
+++ b/src/enm/study-XLSX-54374c80-9b0b-422b-b7d6-1b88ff2559d7.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-54374c80-9b0b-422b-b7d6-1b88ff2559d7",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-95020ff3-17ee-3889-8a9f-f2555dc4a930"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "004",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "004",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Bath"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 6.4
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 6.4
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 18
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-565b07e5-e902-4963-874c-29d6481bc951.json b/src/enm/study-XLSX-565b07e5-e902-4963-874c-29d6481bc951.json
new file mode 100644
index 0000000..78b1386
--- /dev/null
+++ b/src/enm/study-XLSX-565b07e5-e902-4963-874c-29d6481bc951.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-565b07e5-e902-4963-874c-29d6481bc951",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-75ca4d9f-546f-3d7d-a24e-d0d54809cbb3"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "039",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "039",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 225
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-5660a7b2-635d-448e-9ed0-9a27c74b8a35.json b/src/enm/study-XLSX-5660a7b2-635d-448e-9ed0-9a27c74b8a35.json
new file mode 100644
index 0000000..255f24a
--- /dev/null
+++ b/src/enm/study-XLSX-5660a7b2-635d-448e-9ed0-9a27c74b8a35.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-5660a7b2-635d-448e-9ed0-9a27c74b8a35",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-0bfa2e41-c6b6-3cbf-8a1e-73bf006768ab"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "026",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "026",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "THP-1 macrophage",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 48,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 1499.586
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 1890.503
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 15.637
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-57070dcb-b8f4-417c-bd32-821515cb654b.json b/src/enm/study-XLSX-57070dcb-b8f4-417c-bd32-821515cb654b.json
new file mode 100644
index 0000000..dd328c1
--- /dev/null
+++ b/src/enm/study-XLSX-57070dcb-b8f4-417c-bd32-821515cb654b.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-57070dcb-b8f4-417c-bd32-821515cb654b",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-3dac4f9c-8c47-3085-9781-e70583adb12f"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "167",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "167",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Vortexing"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 106
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 178
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 313
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-5735a27c-52fb-4fca-bd17-13780345dcf5.json b/src/enm/study-XLSX-5735a27c-52fb-4fca-bd17-13780345dcf5.json
new file mode 100644
index 0000000..3ca5ee3
--- /dev/null
+++ b/src/enm/study-XLSX-5735a27c-52fb-4fca-bd17-13780345dcf5.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-5735a27c-52fb-4fca-bd17-13780345dcf5",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-f1b0af03-df66-3849-93cc-4ca706c0f751"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "166",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "166",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 24.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-5897d5fa-1a6b-4b73-9c96-702bcfce3fb5.json b/src/enm/study-XLSX-5897d5fa-1a6b-4b73-9c96-702bcfce3fb5.json
new file mode 100644
index 0000000..aa52ed8
--- /dev/null
+++ b/src/enm/study-XLSX-5897d5fa-1a6b-4b73-9c96-702bcfce3fb5.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-5897d5fa-1a6b-4b73-9c96-702bcfce3fb5",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-bbff7bfc-273b-3dfb-be71-5afb33113e53"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "022",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "022",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -35.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-59f17980-2a41-4525-a518-68576d2ebba8.json b/src/enm/study-XLSX-59f17980-2a41-4525-a518-68576d2ebba8.json
new file mode 100644
index 0000000..483c8bd
--- /dev/null
+++ b/src/enm/study-XLSX-59f17980-2a41-4525-a518-68576d2ebba8.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-59f17980-2a41-4525-a518-68576d2ebba8",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-12620892-23e5-37f4-9644-a82c4240d695"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "150",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "150",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-5ce7f13f-0535-4b46-bf94-28c7566e42e6.json b/src/enm/study-XLSX-5ce7f13f-0535-4b46-bf94-28c7566e42e6.json
new file mode 100644
index 0000000..6917546
--- /dev/null
+++ b/src/enm/study-XLSX-5ce7f13f-0535-4b46-bf94-28c7566e42e6.json
@@ -0,0 +1,1016 @@
+{
+ "uuid": "XLSX-5ce7f13f-0535-4b46-bf94-28c7566e42e6",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-93b2da85-fc0c-315f-8d3b-77f1a7776fb4"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "Cell viability - cell membrane damage: Lactate dehydrogenase assay (LDH) (CytoTox 96® Non-radioactive cytotoxicity assay - Promega, G1780) ",
+ "guideline": [
+ "Cytotoxicity using human monocyte-derived macrophages (HMDM)"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "N",
+ "CLO_0000031": "HMDM",
+ "CLO_0000031 EFO_0004443": "Karolinska University Hospital, Stockholm, Sweden - buffy coats from healthy adult blood donors ",
+ "Cell culture conditions - Serum": "FBS (Gibco, 10500) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": "0,05%",
+ "Cell line/Type - Full name": "Primary human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "Y",
+ "NPO_1961": "Y",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, R0833)"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 99.413
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 99.916
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 99.495
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 98.373
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 97.147
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 93.705
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 82.427
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 99.36
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 99.216
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.477
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.174
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.889
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 93.054
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 77.011
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 93.623
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 97.956
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "Concentration": {
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+ "loValue": 10,
+ "unit": "µg/ml"
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.911
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 75.319
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 50,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 66.08
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 41.821
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 100,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 39.382
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 1,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 89.377
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 89.038
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 25,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 82.868
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 70.673
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 75,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 55.286
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 36.018
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 92.006
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 86.708
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 87.863
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 90.631
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 81.019
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 70.953
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 54.229
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 0,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 3",
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+ "unit": "h"
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+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 116.133
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 127.122
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 105.346
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+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 25,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 97.885
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 24,
+ "unit": "h"
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new file mode 100644
index 0000000..f48cd96
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@@ -0,0 +1,75 @@
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index 0000000..dd91dbb
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index 0000000..0d2461e
--- /dev/null
+++ b/src/enm/study-XLSX-6132171d-adcc-40b1-b878-f7348210ef70.json
@@ -0,0 +1,53 @@
+{
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index 0000000..e0913c9
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+{
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index 0000000..3bcc805
--- /dev/null
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+{
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new file mode 100644
index 0000000..546774d
--- /dev/null
+++ b/src/enm/study-XLSX-643341e8-2f22-493d-9800-e380396d8836.json
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+{
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--- /dev/null
+++ b/src/enm/study-XLSX-6510c098-2038-48d8-8484-9594fb095335.json
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+{
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new file mode 100644
index 0000000..5e7c3cd
--- /dev/null
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+{
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index 0000000..ed15e42
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+ "substance": {
+ "uuid": "XLSX-7394378e-b717-3418-a3f7-27db3cbbd8d0"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "035",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "035",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Tip"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 67
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 4048
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 798
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-7677b950-92fc-4190-b1da-9830605be921.json b/src/enm/study-XLSX-7677b950-92fc-4190-b1da-9830605be921.json
new file mode 100644
index 0000000..3f917ad
--- /dev/null
+++ b/src/enm/study-XLSX-7677b950-92fc-4190-b1da-9830605be921.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-7677b950-92fc-4190-b1da-9830605be921",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-de76fc02-ef1f-310a-b61f-6aab5b586412"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "119",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "119",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -46.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-7801fc1f-f78e-439b-86d8-605aac5829f9.json b/src/enm/study-XLSX-7801fc1f-f78e-439b-86d8-605aac5829f9.json
new file mode 100644
index 0000000..a1d3fb5
--- /dev/null
+++ b/src/enm/study-XLSX-7801fc1f-f78e-439b-86d8-605aac5829f9.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-7801fc1f-f78e-439b-86d8-605aac5829f9",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-12620892-23e5-37f4-9644-a82c4240d695"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "150",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "150",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "elongated and rounded"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-782237c1-fdd9-4a31-98f2-9cac8437cafa.json b/src/enm/study-XLSX-782237c1-fdd9-4a31-98f2-9cac8437cafa.json
new file mode 100644
index 0000000..3a0f5d8
--- /dev/null
+++ b/src/enm/study-XLSX-782237c1-fdd9-4a31-98f2-9cac8437cafa.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-782237c1-fdd9-4a31-98f2-9cac8437cafa",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5d7807f7-a13b-392f-88af-fe7885a67502"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "170",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "170",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Mainly 2 euhedral morphologies: aspect ratio of 1 (20–250 nm and 400 nm) and 2:7,5 (50-350 nm)"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.68
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-78a5f27b-1b7b-4416-8ff7-b981d833eac7.json b/src/enm/study-XLSX-78a5f27b-1b7b-4416-8ff7-b981d833eac7.json
new file mode 100644
index 0000000..138a032
--- /dev/null
+++ b/src/enm/study-XLSX-78a5f27b-1b7b-4416-8ff7-b981d833eac7.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-78a5f27b-1b7b-4416-8ff7-b981d833eac7",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-2acfa382-5109-3e49-9fd4-ef8d139be4b2"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "103",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "103",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Vortexing"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 25
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 30
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 20
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-7942c6c5-07a2-4d75-8ee1-7994d617ded4.json b/src/enm/study-XLSX-7942c6c5-07a2-4d75-8ee1-7994d617ded4.json
new file mode 100644
index 0000000..d88ebee
--- /dev/null
+++ b/src/enm/study-XLSX-7942c6c5-07a2-4d75-8ee1-7994d617ded4.json
@@ -0,0 +1,57 @@
+{
+ "uuid": "XLSX-7942c6c5-07a2-4d75-8ee1-7994d617ded4",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-95020ff3-17ee-3889-8a9f-f2555dc4a930"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "002",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "002",
+ "guideline": [
+ "LDH"
+ ]
+ },
+ "parameters": {
+ "Cell line": "THP-1 macrophage",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 48,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.0
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-79993424-da62-4832-a593-a3fddf1215dc.json b/src/enm/study-XLSX-79993424-da62-4832-a593-a3fddf1215dc.json
new file mode 100644
index 0000000..3719b28
--- /dev/null
+++ b/src/enm/study-XLSX-79993424-da62-4832-a593-a3fddf1215dc.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-79993424-da62-4832-a593-a3fddf1215dc",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-673c8355-a823-3bf2-a319-0d8af43e4d90"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "149",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "149",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-7b6bef82-33d5-496b-8a67-98dc25612972.json b/src/enm/study-XLSX-7b6bef82-33d5-496b-8a67-98dc25612972.json
new file mode 100644
index 0000000..87ae39b
--- /dev/null
+++ b/src/enm/study-XLSX-7b6bef82-33d5-496b-8a67-98dc25612972.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-7b6bef82-33d5-496b-8a67-98dc25612972",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d4f2714a-a7f6-305a-af41-18d8129fef13"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "184",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "184",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": 40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-7b7d74b3-17f0-4d27-b99d-e8f9783c78f9.json b/src/enm/study-XLSX-7b7d74b3-17f0-4d27-b99d-e8f9783c78f9.json
new file mode 100644
index 0000000..7cd9f93
--- /dev/null
+++ b/src/enm/study-XLSX-7b7d74b3-17f0-4d27-b99d-e8f9783c78f9.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-7b7d74b3-17f0-4d27-b99d-e8f9783c78f9",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-53ac37fa-9e10-3f71-9d74-bc47f28880ff"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "185",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "185",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ },
+ "result": {
+ "unit": "m2/g",
+ "loValue": 77.992
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-7da1da69-ac0c-430b-a5de-f15d0c51d1dd.json b/src/enm/study-XLSX-7da1da69-ac0c-430b-a5de-f15d0c51d1dd.json
new file mode 100644
index 0000000..de06eb0
--- /dev/null
+++ b/src/enm/study-XLSX-7da1da69-ac0c-430b-a5de-f15d0c51d1dd.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-7da1da69-ac0c-430b-a5de-f15d0c51d1dd",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-2aef353b-440f-32a7-8447-1974997a69a8"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "190",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "190",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "polyhedral with irregular morphology"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-7de5aa9c-02e2-410a-a1ac-cc5518f2ddd6.json b/src/enm/study-XLSX-7de5aa9c-02e2-410a-a1ac-cc5518f2ddd6.json
new file mode 100644
index 0000000..506d325
--- /dev/null
+++ b/src/enm/study-XLSX-7de5aa9c-02e2-410a-a1ac-cc5518f2ddd6.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-7de5aa9c-02e2-410a-a1ac-cc5518f2ddd6",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d6285533-0204-3884-a3d8-1dffdcde6324"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "070",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0010001_SECTION",
+ "term": "http://purl.bioontology.org/ontology/bao#BAO_0010001",
+ "title": "BAO_0010001 ATP Assay"
+ },
+ "endpoint": "070",
+ "guideline": [
+ "ATP"
+ ]
+ },
+ "parameters": {
+ "Cell line": "U-87 MG",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": "0,5",
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 42.557
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 117.994
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 3.017
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-7ee9bf0a-db20-45b9-bb5a-0a162e9fd458.json b/src/enm/study-XLSX-7ee9bf0a-db20-45b9-bb5a-0a162e9fd458.json
new file mode 100644
index 0000000..95c3314
--- /dev/null
+++ b/src/enm/study-XLSX-7ee9bf0a-db20-45b9-bb5a-0a162e9fd458.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-7ee9bf0a-db20-45b9-bb5a-0a162e9fd458",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-f1b0af03-df66-3849-93cc-4ca706c0f751"
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+ "company": {
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--- /dev/null
+++ b/src/enm/study-XLSX-832963bb-ee15-45e0-83de-ed54449e8369.json
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+{
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+{
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+{
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+{
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+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 4.559
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-8780e971-9a1e-4c96-b7dd-df6906f459c1.json b/src/enm/study-XLSX-8780e971-9a1e-4c96-b7dd-df6906f459c1.json
new file mode 100644
index 0000000..aac3386
--- /dev/null
+++ b/src/enm/study-XLSX-8780e971-9a1e-4c96-b7dd-df6906f459c1.json
@@ -0,0 +1,1016 @@
+{
+ "uuid": "XLSX-8780e971-9a1e-4c96-b7dd-df6906f459c1",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-7011cea0-1011-3f8b-9e8a-b3289fed836a"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "Cell viability - cell membrane damage: Lactate dehydrogenase assay (LDH) (CytoTox 96® Non-radioactive cytotoxicity assay - Promega, G1780) ",
+ "guideline": [
+ "Cytotoxicity using human monocyte-derived macrophages (HMDM)"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "N",
+ "CLO_0000031": "HMDM",
+ "CLO_0000031 EFO_0004443": "Karolinska University Hospital, Stockholm, Sweden - buffy coats from healthy adult blood donors ",
+ "Cell culture conditions - Serum": "FBS (Gibco, 10500) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": "0,05%",
+ "Cell line/Type - Full name": "Primary human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "Y",
+ "NPO_1961": "Y",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, R0833)"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.294
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 95.395
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 93.312
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.568
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 102.257
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.158
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 102.301
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 98.551
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 98.341
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 98.816
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 97.54
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100.042
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 98.508
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.204
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 91.546
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.817
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 93.689
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 95.606
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 98.021
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 95.369
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100.478
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100.029
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 97.715
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.152
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.331
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 94.293
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 82.224
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 83.231
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 90.843
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 86.566
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 82.579
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 84.673
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 89.69
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 91.093
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 92.472
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 102.679
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 98.516
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 95.758
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.941
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 94.554
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 75,
+ "unit": "µg/ml"
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new file mode 100644
index 0000000..7587b92
--- /dev/null
+++ b/src/enm/study-XLSX-87c24669-daee-4ac4-965e-a572347ed807.json
@@ -0,0 +1,75 @@
+{
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index 0000000..270db70
--- /dev/null
+++ b/src/enm/study-XLSX-880c0005-b5fa-4e6d-8f57-46dfbed10eaf.json
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+{
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diff --git a/src/enm/study-XLSX-880d9d94-b9be-4703-bf64-b4e72f1f0ba8.json b/src/enm/study-XLSX-880d9d94-b9be-4703-bf64-b4e72f1f0ba8.json
new file mode 100644
index 0000000..5b89a30
--- /dev/null
+++ b/src/enm/study-XLSX-880d9d94-b9be-4703-bf64-b4e72f1f0ba8.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "XLSX-880d9d94-b9be-4703-bf64-b4e72f1f0ba8",
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index 0000000..6ab81a2
--- /dev/null
+++ b/src/enm/study-XLSX-89e92622-b378-4c27-a247-69e57ddec991.json
@@ -0,0 +1,72 @@
+{
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new file mode 100644
index 0000000..62fc4c7
--- /dev/null
+++ b/src/enm/study-XLSX-8a271daf-f41f-4db8-8e04-e8a5da3184e1.json
@@ -0,0 +1,75 @@
+{
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new file mode 100644
index 0000000..6eda8f5
--- /dev/null
+++ b/src/enm/study-XLSX-8af9c4ff-0461-4138-b733-8e3b4df15e36.json
@@ -0,0 +1,75 @@
+{
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+ "year": "2015",
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+ "title": "NPO_1709 LDH Release Assay"
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+ "endpoint": "173",
+ "guideline": [
+ "LDH"
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diff --git a/src/enm/study-XLSX-8bfb303d-bf11-40fa-8492-af33b2e6b811.json b/src/enm/study-XLSX-8bfb303d-bf11-40fa-8492-af33b2e6b811.json
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index 0000000..9709d31
--- /dev/null
+++ b/src/enm/study-XLSX-8bfb303d-bf11-40fa-8492-af33b2e6b811.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-8bfb303d-bf11-40fa-8492-af33b2e6b811",
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+ "name": "MODENA"
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+ "year": "2015",
+ "owner": "MODENA"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "083",
+ "guideline": [
+ "Shape"
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new file mode 100644
index 0000000..d0a282f
--- /dev/null
+++ b/src/enm/study-XLSX-8c3d195c-d59b-4530-b812-9b3ffcb05fd0.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-8c3d195c-d59b-4530-b812-9b3ffcb05fd0",
+ "owner": {
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+ "name": "MODENA"
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+ "year": "2015",
+ "owner": "MODENA"
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+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "021",
+ "guideline": [
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+ ]
+ },
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diff --git a/src/enm/study-XLSX-8c62011c-fc3c-4f25-bb5e-80cef1c29bad.json b/src/enm/study-XLSX-8c62011c-fc3c-4f25-bb5e-80cef1c29bad.json
new file mode 100644
index 0000000..a9b0edf
--- /dev/null
+++ b/src/enm/study-XLSX-8c62011c-fc3c-4f25-bb5e-80cef1c29bad.json
@@ -0,0 +1,53 @@
+{
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+ "title": "4.29 Nanomaterial zeta potential"
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+ "endpoint": "141",
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diff --git a/src/enm/study-XLSX-8c7190f0-de46-4f3c-a435-b4954125d617.json b/src/enm/study-XLSX-8c7190f0-de46-4f3c-a435-b4954125d617.json
new file mode 100644
index 0000000..4bd953f
--- /dev/null
+++ b/src/enm/study-XLSX-8c7190f0-de46-4f3c-a435-b4954125d617.json
@@ -0,0 +1,75 @@
+{
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+ "title": "BAO_0003009 Cell Viability Assay"
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+++ b/src/enm/study-XLSX-941c33b0-476d-4bbf-9ff2-cd195483746b.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-941c33b0-476d-4bbf-9ff2-cd195483746b",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-7394378e-b717-3418-a3f7-27db3cbbd8d0"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "034",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "034",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "NRK-52E",
+ "Dispersion protocol": "Tip",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 664.216
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 4318.666
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 146.178
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-95750335-a736-4142-9e08-b20fd61a57ce.json b/src/enm/study-XLSX-95750335-a736-4142-9e08-b20fd61a57ce.json
new file mode 100644
index 0000000..fa3654e
--- /dev/null
+++ b/src/enm/study-XLSX-95750335-a736-4142-9e08-b20fd61a57ce.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-95750335-a736-4142-9e08-b20fd61a57ce",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d6285533-0204-3884-a3d8-1dffdcde6324"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "075",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "075",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": ""
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-95aee53d-3b33-4256-a631-60d4914942ee.json b/src/enm/study-XLSX-95aee53d-3b33-4256-a631-60d4914942ee.json
new file mode 100644
index 0000000..8030e93
--- /dev/null
+++ b/src/enm/study-XLSX-95aee53d-3b33-4256-a631-60d4914942ee.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-95aee53d-3b33-4256-a631-60d4914942ee",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-9eb0db98-07c0-37fb-9fc3-7126d72252c4"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "131",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "131",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "THP-1 macrophage",
+ "Dispersion protocol": "Stirring",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 7.888
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 18.856
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.439
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-95ced9d3-da9a-4a70-9023-75dd5ca53e4d.json b/src/enm/study-XLSX-95ced9d3-da9a-4a70-9023-75dd5ca53e4d.json
new file mode 100644
index 0000000..7ddc8d4
--- /dev/null
+++ b/src/enm/study-XLSX-95ced9d3-da9a-4a70-9023-75dd5ca53e4d.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-95ced9d3-da9a-4a70-9023-75dd5ca53e4d",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-a0d9ab63-ee03-3224-984a-4bd276e3ea3a"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "143",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "143",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "elongated"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.7
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-988b517f-37db-4a85-a9cd-5dd7ca6a7451.json b/src/enm/study-XLSX-988b517f-37db-4a85-a9cd-5dd7ca6a7451.json
new file mode 100644
index 0000000..951a8ee
--- /dev/null
+++ b/src/enm/study-XLSX-988b517f-37db-4a85-a9cd-5dd7ca6a7451.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-988b517f-37db-4a85-a9cd-5dd7ca6a7451",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-3dac4f9c-8c47-3085-9781-e70583adb12f"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "167",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "167",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "NCI-H292",
+ "Dispersion protocol": "Vortexing",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 2.051
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 2.632
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.023
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-99fae757-27bf-4193-9f98-119ee64ce72a.json b/src/enm/study-XLSX-99fae757-27bf-4193-9f98-119ee64ce72a.json
new file mode 100644
index 0000000..8765aa4
--- /dev/null
+++ b/src/enm/study-XLSX-99fae757-27bf-4193-9f98-119ee64ce72a.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-99fae757-27bf-4193-9f98-119ee64ce72a",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-92788191-34d9-39b4-aa9c-503da51fc1a6"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "134",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "134",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Tip"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 21
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 25
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 228.3
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-9b36b98c-5251-4eb7-a94d-e133bdfe2037.json b/src/enm/study-XLSX-9b36b98c-5251-4eb7-a94d-e133bdfe2037.json
new file mode 100644
index 0000000..d0702e2
--- /dev/null
+++ b/src/enm/study-XLSX-9b36b98c-5251-4eb7-a94d-e133bdfe2037.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-9b36b98c-5251-4eb7-a94d-e133bdfe2037",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-64e97bde-be4b-34fb-b216-85724e66b02a"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "153",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "153",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "irregular"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.36
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-9c8b990c-b31c-493e-8d3e-e1d4fa9ab680.json b/src/enm/study-XLSX-9c8b990c-b31c-493e-8d3e-e1d4fa9ab680.json
new file mode 100644
index 0000000..f6c3adc
--- /dev/null
+++ b/src/enm/study-XLSX-9c8b990c-b31c-493e-8d3e-e1d4fa9ab680.json
@@ -0,0 +1,1016 @@
+{
+ "uuid": "XLSX-9c8b990c-b31c-493e-8d3e-e1d4fa9ab680",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-ffd24485-3b05-3afe-b6ff-547800723f71"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "Cell viability - cell membrane damage: Lactate dehydrogenase assay (LDH) (CytoTox 96® Non-radioactive cytotoxicity assay - Promega, G1780) ",
+ "guideline": [
+ "Cytotoxicity using human monocyte-derived macrophages (HMDM)"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "N",
+ "CLO_0000031": "HMDM",
+ "CLO_0000031 EFO_0004443": "Karolinska University Hospital, Stockholm, Sweden - buffy coats from healthy adult blood donors ",
+ "Cell culture conditions - Serum": "FBS (Gibco, 10500) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": "0,05%",
+ "Cell line/Type - Full name": "Primary human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "Y",
+ "NPO_1961": "Y",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, R0833)"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 108.781
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 106.652
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 10,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 107.078
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 112.329
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
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+ "loValue": 102.237
+ }
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+ {
+ "endpoint": "% cell viability",
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+ "unit": "µg/ml"
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+ "Replicate": "Replicate 2",
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "unit": "h"
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+ "result": {
+ "unit": "%",
+ "loValue": 95.211
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "unit": "µg/ml"
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+ "Replicate": "Replicate 2",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 91.927
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 92.629
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 93.728
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 88.661
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "unit": "h"
+ }
+ },
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+ "loValue": 100.11
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 6,
+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 50,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
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+ },
+ {
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+ "loValue": 75,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 100,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 0,
+ "unit": "µg/ml"
+ },
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "unit": "µg/ml"
+ },
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
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+ "unit": "h"
+ }
+ },
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+ },
+ {
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+ "unit": "µg/ml"
+ },
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "% cell viability",
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+ "unit": "µg/ml"
+ },
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+ "unit": "h"
+ }
+ },
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+ },
+ {
+ "endpoint": "% cell viability",
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+ "loValue": 100,
+ "unit": "µg/ml"
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+ "Replicate": "Replicate 1",
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ },
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+ "loValue": 0,
+ "unit": "µg/ml"
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+ "unit": "h"
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+ },
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+ },
+ {
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+ "unit": "µg/ml"
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+ "unit": "µg/ml"
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+ },
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+ }
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+ "unit": "h"
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+ },
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ {
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ "unit": "h"
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ {
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+ "unit": "µg/ml"
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+ "unit": "h"
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+ },
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+ },
+ {
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+ "unit": "µg/ml"
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
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+ "unit": "µg/ml"
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
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+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 96.042
+ }
+ },
+ {
+ "endpoint": "% cell viability",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "%",
+ "loValue": 92.458
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-9d7cf58e-ab64-4366-9860-e81db77b8916.json b/src/enm/study-XLSX-9d7cf58e-ab64-4366-9860-e81db77b8916.json
new file mode 100644
index 0000000..5a26cda
--- /dev/null
+++ b/src/enm/study-XLSX-9d7cf58e-ab64-4366-9860-e81db77b8916.json
@@ -0,0 +1,51 @@
+{
+ "uuid": "XLSX-9d7cf58e-ab64-4366-9860-e81db77b8916",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-dce22e5a-6ef2-3fd1-b1c8-9ebdb7bd5d2f"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "063",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "063",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Heterogeneous"
+ },
+ "effects": [
+ {
+ "endpoint": "",
+ "conditions": {
+ },
+ "result": {
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-9eed2c42-e5da-44ca-98b8-a8683e6eb4d9.json b/src/enm/study-XLSX-9eed2c42-e5da-44ca-98b8-a8683e6eb4d9.json
new file mode 100644
index 0000000..37ef936
--- /dev/null
+++ b/src/enm/study-XLSX-9eed2c42-e5da-44ca-98b8-a8683e6eb4d9.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-9eed2c42-e5da-44ca-98b8-a8683e6eb4d9",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-2acfa382-5109-3e49-9fd4-ef8d139be4b2"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "103",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "103",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "round/oblong"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.2
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-9fb561c6-a921-4171-a484-ecafa9355f43.json b/src/enm/study-XLSX-9fb561c6-a921-4171-a484-ecafa9355f43.json
new file mode 100644
index 0000000..2c8509b
--- /dev/null
+++ b/src/enm/study-XLSX-9fb561c6-a921-4171-a484-ecafa9355f43.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-9fb561c6-a921-4171-a484-ecafa9355f43",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5cd11301-7cf1-3402-aaf8-853e5ed8ccde"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "177",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "177",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Vortexing"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 101
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 170
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 310
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-a047ee3a-7b56-4e5f-bdae-3695eefb80a1.json b/src/enm/study-XLSX-a047ee3a-7b56-4e5f-bdae-3695eefb80a1.json
new file mode 100644
index 0000000..93c084c
--- /dev/null
+++ b/src/enm/study-XLSX-a047ee3a-7b56-4e5f-bdae-3695eefb80a1.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-a047ee3a-7b56-4e5f-bdae-3695eefb80a1",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-9eb0db98-07c0-37fb-9fc3-7126d72252c4"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "130",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "130",
+ "guideline": [
+ "WST-1"
+ ]
+ },
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+{
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+{
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diff --git a/src/enm/study-XLSX-a1429af3-925b-4fd0-9652-3144efbe96bf.json b/src/enm/study-XLSX-a1429af3-925b-4fd0-9652-3144efbe96bf.json
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index 0000000..c424db9
--- /dev/null
+++ b/src/enm/study-XLSX-a1429af3-925b-4fd0-9652-3144efbe96bf.json
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+{
+ "uuid": "XLSX-a1429af3-925b-4fd0-9652-3144efbe96bf",
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--- /dev/null
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+{
+ "uuid": "XLSX-a1d6108c-3461-41dc-bf7a-f83cedb47e41",
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+{
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diff --git a/src/enm/study-XLSX-a336e49f-75ba-477d-acb6-7d6abe0eff8f.json b/src/enm/study-XLSX-a336e49f-75ba-477d-acb6-7d6abe0eff8f.json
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index 0000000..d888e7b
--- /dev/null
+++ b/src/enm/study-XLSX-a336e49f-75ba-477d-acb6-7d6abe0eff8f.json
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+{
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index 0000000..d12fc7b
--- /dev/null
+++ b/src/enm/study-XLSX-a43d29ec-b7f4-40ef-a9fc-9178db646c83.json
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+{
+ "uuid": "XLSX-a43d29ec-b7f4-40ef-a9fc-9178db646c83",
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+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
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diff --git a/src/enm/study-XLSX-a5483c3a-0b3e-400f-aff8-55dd5a1599bd.json b/src/enm/study-XLSX-a5483c3a-0b3e-400f-aff8-55dd5a1599bd.json
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--- /dev/null
+++ b/src/enm/study-XLSX-a5483c3a-0b3e-400f-aff8-55dd5a1599bd.json
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+{
+ "uuid": "XLSX-a5483c3a-0b3e-400f-aff8-55dd5a1599bd",
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+ "year": "2015",
+ "owner": "MODENA"
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+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
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diff --git a/src/enm/study-XLSX-a56cbeaa-ece4-4768-a70c-bc54bb329b78.json b/src/enm/study-XLSX-a56cbeaa-ece4-4768-a70c-bc54bb329b78.json
new file mode 100644
index 0000000..bfcf856
--- /dev/null
+++ b/src/enm/study-XLSX-a56cbeaa-ece4-4768-a70c-bc54bb329b78.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-a56cbeaa-ece4-4768-a70c-bc54bb329b78",
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
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+ "title": "176",
+ "year": "2015",
+ "owner": "MODENA"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
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diff --git a/src/enm/study-XLSX-a5a35727-466c-4ffb-acb8-e33b79af6e3e.json b/src/enm/study-XLSX-a5a35727-466c-4ffb-acb8-e33b79af6e3e.json
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index 0000000..a625582
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+++ b/src/enm/study-XLSX-a5a35727-466c-4ffb-acb8-e33b79af6e3e.json
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+{
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+{
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index 0000000..b23b1f2
--- /dev/null
+++ b/src/enm/study-XLSX-b1b21fdc-b9aa-4783-a17f-379734d0574c.json
@@ -0,0 +1,53 @@
+{
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+{
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+{
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--- /dev/null
+++ b/src/enm/study-XLSX-b65865f0-f8d0-43fa-9395-f8416d794590.json
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+{
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+{
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--- /dev/null
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@@ -0,0 +1,53 @@
+{
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+ {
+ "endpoint": "SLOPE EC50",
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+ "result": {
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diff --git a/src/enm/study-XLSX-c9c7dce2-9d8e-4f47-a93e-aac7c27f5f58.json b/src/enm/study-XLSX-c9c7dce2-9d8e-4f47-a93e-aac7c27f5f58.json
new file mode 100644
index 0000000..3980b8a
--- /dev/null
+++ b/src/enm/study-XLSX-c9c7dce2-9d8e-4f47-a93e-aac7c27f5f58.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-c9c7dce2-9d8e-4f47-a93e-aac7c27f5f58",
+ "owner": {
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
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+ "citation": {
+ "title": "116",
+ "year": "2015",
+ "owner": "MODENA"
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+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "116",
+ "guideline": [
+ "LDH"
+ ]
+ },
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+ "Serum concentration,%": 0.1
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+ "endpoint": "EC25",
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+ "loValue": 240.376
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diff --git a/src/enm/study-XLSX-c9d5a3c3-257e-41cf-a445-b6747c2f7fd2.json b/src/enm/study-XLSX-c9d5a3c3-257e-41cf-a445-b6747c2f7fd2.json
new file mode 100644
index 0000000..c84e19e
--- /dev/null
+++ b/src/enm/study-XLSX-c9d5a3c3-257e-41cf-a445-b6747c2f7fd2.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-c9d5a3c3-257e-41cf-a445-b6747c2f7fd2",
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
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+ "year": "2015",
+ "owner": "MODENA"
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+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "019",
+ "guideline": [
+ "TEM"
+ ]
+ },
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+ "Dispersion protocol": "Vortexing"
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+ },
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+ },
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+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
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+ "result": {
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+ "loValue": 14
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
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+ "result": {
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+}
diff --git a/src/enm/study-XLSX-ca32b798-cba0-4a0a-89cd-5eeebef7dafc.json b/src/enm/study-XLSX-ca32b798-cba0-4a0a-89cd-5eeebef7dafc.json
new file mode 100644
index 0000000..805c8f3
--- /dev/null
+++ b/src/enm/study-XLSX-ca32b798-cba0-4a0a-89cd-5eeebef7dafc.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-ca32b798-cba0-4a0a-89cd-5eeebef7dafc",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-75ca4d9f-546f-3d7d-a24e-d0d54809cbb3"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "039",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "039",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
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+ "r_studyResultType": "experimental result",
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+ },
+ "interpretation": {
+ "result": "Entangled irregular, mostly bent, some no-onions "
+ },
+ "effects": [
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+ "endpoint": "ASPECT RATIO",
+ "conditions": {
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+ "loValue": 125
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diff --git a/src/enm/study-XLSX-ca6e4f24-b2f5-41c0-ad58-13bbfa3265ab.json b/src/enm/study-XLSX-ca6e4f24-b2f5-41c0-ad58-13bbfa3265ab.json
new file mode 100644
index 0000000..a836507
--- /dev/null
+++ b/src/enm/study-XLSX-ca6e4f24-b2f5-41c0-ad58-13bbfa3265ab.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-ca6e4f24-b2f5-41c0-ad58-13bbfa3265ab",
+ "owner": {
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
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+ "year": "2015",
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+ "code": "PC_GRANULOMETRY_SECTION",
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+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "149",
+ "guideline": [
+ "TEM"
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+ "loValue": 21.8
+ }
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diff --git a/src/enm/study-XLSX-caa33b31-8bb6-4f2b-a83c-1f11b0ad7da8.json b/src/enm/study-XLSX-caa33b31-8bb6-4f2b-a83c-1f11b0ad7da8.json
new file mode 100644
index 0000000..9d21ba1
--- /dev/null
+++ b/src/enm/study-XLSX-caa33b31-8bb6-4f2b-a83c-1f11b0ad7da8.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-caa33b31-8bb6-4f2b-a83c-1f11b0ad7da8",
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+ "title": "BAO_0003009 Cell Viability Assay"
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+ "endpoint": "149",
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+ "WST-1"
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+ "Serum concentration,%": 0.1
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new file mode 100644
index 0000000..e0e18be
--- /dev/null
+++ b/src/enm/study-XLSX-cae175fa-1f2f-4d52-8d0b-0af9747925ca.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-cae175fa-1f2f-4d52-8d0b-0af9747925ca",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-9eb0db98-07c0-37fb-9fc3-7126d72252c4"
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
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+ "citation": {
+ "title": "131",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "131",
+ "guideline": [
+ "Shape"
+ ]
+ },
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+ "r_studyResultType": "experimental result",
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+ },
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diff --git a/src/enm/study-XLSX-cb77a276-f477-4d81-8823-5786a7014f6c.json b/src/enm/study-XLSX-cb77a276-f477-4d81-8823-5786a7014f6c.json
new file mode 100644
index 0000000..4650fe2
--- /dev/null
+++ b/src/enm/study-XLSX-cb77a276-f477-4d81-8823-5786a7014f6c.json
@@ -0,0 +1,56 @@
+{
+ "uuid": "XLSX-cb77a276-f477-4d81-8823-5786a7014f6c",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5d7807f7-a13b-392f-88af-fe7885a67502"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
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+ "citation": {
+ "title": "170",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "170",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
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+ },
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ },
+ "result": {
+ "unit": "m2/g",
+ "loQualifier": ">=",
+ "loValue": 11.8,
+ "upQualifier": "<=",
+ "upValue": 13
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-cbb1aca6-72b7-4d98-b3c7-1e02bbe5323a.json b/src/enm/study-XLSX-cbb1aca6-72b7-4d98-b3c7-1e02bbe5323a.json
new file mode 100644
index 0000000..7d8872e
--- /dev/null
+++ b/src/enm/study-XLSX-cbb1aca6-72b7-4d98-b3c7-1e02bbe5323a.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-cbb1aca6-72b7-4d98-b3c7-1e02bbe5323a",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-0d71a921-0e8d-3f25-8deb-20478b7e884b"
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
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+ "year": "2015",
+ "owner": "MODENA"
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+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "126",
+ "guideline": [
+ "WST-1"
+ ]
+ },
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+ "Serum concentration,%": 0
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+ "loValue": 113.814
+ }
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diff --git a/src/enm/study-XLSX-cbe445cd-8bb9-49ef-bd3e-f3659f6bfb25.json b/src/enm/study-XLSX-cbe445cd-8bb9-49ef-bd3e-f3659f6bfb25.json
new file mode 100644
index 0000000..3c0a14c
--- /dev/null
+++ b/src/enm/study-XLSX-cbe445cd-8bb9-49ef-bd3e-f3659f6bfb25.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-cbe445cd-8bb9-49ef-bd3e-f3659f6bfb25",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-4ceef1bf-5f19-34e7-9d3d-51d65be297d7"
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+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "171",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "171",
+ "guideline": [
+ "LDH"
+ ]
+ },
+ "parameters": {
+ "Cell line": "A549",
+ "Dispersion protocol": "Tip",
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+ "Serum concentration,%": 0.1
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+ }
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+ "result": {
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+ }
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diff --git a/src/enm/study-XLSX-cd5d66d7-ae58-4bab-af4d-56f29f986660.json b/src/enm/study-XLSX-cd5d66d7-ae58-4bab-af4d-56f29f986660.json
new file mode 100644
index 0000000..5918609
--- /dev/null
+++ b/src/enm/study-XLSX-cd5d66d7-ae58-4bab-af4d-56f29f986660.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-cd5d66d7-ae58-4bab-af4d-56f29f986660",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-295d65e6-0d6e-3987-a67f-e4482fa28c71"
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+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
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+ },
+ "citation": {
+ "title": "099",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "099",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
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+ "unit": "ug/ml",
+ "loValue": 106.213
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 0.342
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-df2b7cc9-9440-4450-93b4-0b01cfbe0470.json b/src/enm/study-XLSX-df2b7cc9-9440-4450-93b4-0b01cfbe0470.json
new file mode 100644
index 0000000..5678a23
--- /dev/null
+++ b/src/enm/study-XLSX-df2b7cc9-9440-4450-93b4-0b01cfbe0470.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-df2b7cc9-9440-4450-93b4-0b01cfbe0470",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-498d791a-4c0f-3eab-bb2b-bd554637d9af"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "135",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "135",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Vortexing"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 8
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 532
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-df2f83d5-775f-4dd1-86f2-221bc53497ca.json b/src/enm/study-XLSX-df2f83d5-775f-4dd1-86f2-221bc53497ca.json
new file mode 100644
index 0000000..21bf5ba
--- /dev/null
+++ b/src/enm/study-XLSX-df2f83d5-775f-4dd1-86f2-221bc53497ca.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-df2f83d5-775f-4dd1-86f2-221bc53497ca",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-945d75a3-50b7-3655-8979-376d39096378"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "029",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "029",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "A549",
+ "Dispersion protocol": "Tip",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 1025.671
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 24233.231
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 928.302
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-df6f1803-e1f2-46a5-8ad2-04aa026cb430.json b/src/enm/study-XLSX-df6f1803-e1f2-46a5-8ad2-04aa026cb430.json
new file mode 100644
index 0000000..49203b3
--- /dev/null
+++ b/src/enm/study-XLSX-df6f1803-e1f2-46a5-8ad2-04aa026cb430.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-df6f1803-e1f2-46a5-8ad2-04aa026cb430",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-9f84408a-4414-33c9-a0f2-53bd19cf2d65"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "155",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "155",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Irregular euhedral"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.36
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-e0924b3c-5b20-4c17-b35b-9d1487aaf32c.json b/src/enm/study-XLSX-e0924b3c-5b20-4c17-b35b-9d1487aaf32c.json
new file mode 100644
index 0000000..87b1ed9
--- /dev/null
+++ b/src/enm/study-XLSX-e0924b3c-5b20-4c17-b35b-9d1487aaf32c.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "XLSX-e0924b3c-5b20-4c17-b35b-9d1487aaf32c",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-75ca4d9f-546f-3d7d-a24e-d0d54809cbb3"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "039",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "039",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Vortexing"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 11
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 1372
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-e12f73c6-c0a0-43b6-b377-b8e4dcf5616c.json b/src/enm/study-XLSX-e12f73c6-c0a0-43b6-b377-b8e4dcf5616c.json
new file mode 100644
index 0000000..034df7a
--- /dev/null
+++ b/src/enm/study-XLSX-e12f73c6-c0a0-43b6-b377-b8e4dcf5616c.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-e12f73c6-c0a0-43b6-b377-b8e4dcf5616c",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-95020ff3-17ee-3889-8a9f-f2555dc4a930"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "004",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "004",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "average round but not as monodisperse"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-e1efd876-a5b6-47d6-9039-04f1b86cac77.json b/src/enm/study-XLSX-e1efd876-a5b6-47d6-9039-04f1b86cac77.json
new file mode 100644
index 0000000..966bae9
--- /dev/null
+++ b/src/enm/study-XLSX-e1efd876-a5b6-47d6-9039-04f1b86cac77.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-e1efd876-a5b6-47d6-9039-04f1b86cac77",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5cd11301-7cf1-3402-aaf8-853e5ed8ccde"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "177",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "177",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Mainly 2 euhedral morphologies: aspect ratio 1(20–250 nm) and aspect ratio 2:8.5 (10–450 nm)"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.68
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-e25fcdda-3935-448e-a5bf-31932f003ed4.json b/src/enm/study-XLSX-e25fcdda-3935-448e-a5bf-31932f003ed4.json
new file mode 100644
index 0000000..38e4478
--- /dev/null
+++ b/src/enm/study-XLSX-e25fcdda-3935-448e-a5bf-31932f003ed4.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-e25fcdda-3935-448e-a5bf-31932f003ed4",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5d07b463-d3a8-35b1-826e-076f9f2328c8"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "081",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "081",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Stirring"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 5
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 12
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 129
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-e2d1e541-119d-48fd-811e-ef18a2f4611c.json b/src/enm/study-XLSX-e2d1e541-119d-48fd-811e-ef18a2f4611c.json
new file mode 100644
index 0000000..e998db8
--- /dev/null
+++ b/src/enm/study-XLSX-e2d1e541-119d-48fd-811e-ef18a2f4611c.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "XLSX-e2d1e541-119d-48fd-811e-ef18a2f4611c",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-56c58705-05c6-304f-bb42-a3a328e06319"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "182",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "182",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Tip"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 106
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 178
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-e39305cf-0a69-4240-9f35-d79a2d429e40.json b/src/enm/study-XLSX-e39305cf-0a69-4240-9f35-d79a2d429e40.json
new file mode 100644
index 0000000..c4b48e8
--- /dev/null
+++ b/src/enm/study-XLSX-e39305cf-0a69-4240-9f35-d79a2d429e40.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-e39305cf-0a69-4240-9f35-d79a2d429e40",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-251091e3-55d1-36b3-854c-d1933ec46461"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "027",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "027",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Vortexing"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 38.1
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 38.1
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 144
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-e3b26a17-3886-4b42-9f8b-51a75c92d549.json b/src/enm/study-XLSX-e3b26a17-3886-4b42-9f8b-51a75c92d549.json
new file mode 100644
index 0000000..a1026a8
--- /dev/null
+++ b/src/enm/study-XLSX-e3b26a17-3886-4b42-9f8b-51a75c92d549.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-e3b26a17-3886-4b42-9f8b-51a75c92d549",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-36cbb933-ec3a-3d8b-b80f-0d5b6e76edc5"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "028",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "028",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -43.8
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-e3b53d4c-5816-4555-93a5-638024e7e6cc.json b/src/enm/study-XLSX-e3b53d4c-5816-4555-93a5-638024e7e6cc.json
new file mode 100644
index 0000000..c1f3ce0
--- /dev/null
+++ b/src/enm/study-XLSX-e3b53d4c-5816-4555-93a5-638024e7e6cc.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-e3b53d4c-5816-4555-93a5-638024e7e6cc",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-38666e26-8f8e-37a4-b97c-728a1e5aa0f2"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "038",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
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new file mode 100644
index 0000000..b89f2e1
--- /dev/null
+++ b/src/enm/study-XLSX-e4d153a8-15a4-473b-a649-a8f173015876.json
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+{
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index 0000000..86a59bf
--- /dev/null
+++ b/src/enm/study-XLSX-e4ec31d9-12a2-492c-8912-6a1caf42d220.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-e4ec31d9-12a2-492c-8912-6a1caf42d220",
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diff --git a/src/enm/study-XLSX-e56d0702-5753-4c06-91bc-637bf5355ce3.json b/src/enm/study-XLSX-e56d0702-5753-4c06-91bc-637bf5355ce3.json
new file mode 100644
index 0000000..181bf70
--- /dev/null
+++ b/src/enm/study-XLSX-e56d0702-5753-4c06-91bc-637bf5355ce3.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-e56d0702-5753-4c06-91bc-637bf5355ce3",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-38666e26-8f8e-37a4-b97c-728a1e5aa0f2"
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
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+ "citation": {
+ "title": "038",
+ "year": "2015",
+ "owner": "MODENA"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "038",
+ "guideline": [
+ "Shape"
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+ },
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new file mode 100644
index 0000000..d9321a1
--- /dev/null
+++ b/src/enm/study-XLSX-e70a0515-81c5-49ef-b2e4-27897942675a.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-e70a0515-81c5-49ef-b2e4-27897942675a",
+ "owner": {
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
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diff --git a/src/enm/study-XLSX-e7aa3d69-db5c-4a6f-b562-22643a5eaae8.json b/src/enm/study-XLSX-e7aa3d69-db5c-4a6f-b562-22643a5eaae8.json
new file mode 100644
index 0000000..f720af4
--- /dev/null
+++ b/src/enm/study-XLSX-e7aa3d69-db5c-4a6f-b562-22643a5eaae8.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-e7aa3d69-db5c-4a6f-b562-22643a5eaae8",
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+ "code": "ASPECT_RATIO_SHAPE_SECTION",
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+ "title": "4.27 Nanomaterial aspect ratio/shape"
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+ "endpoint": "135",
+ "guideline": [
+ "Shape"
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index 0000000..93a877e
--- /dev/null
+++ b/src/enm/study-XLSX-e7dab684-dd3d-4054-a343-31706a073bf6.json
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+{
+ "uuid": "XLSX-e7dab684-dd3d-4054-a343-31706a073bf6",
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+ "endpoint": "134",
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new file mode 100644
index 0000000..72b6721
--- /dev/null
+++ b/src/enm/study-XLSX-e85460d4-1d0a-4cdf-aea6-7025bca3a403.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-e85460d4-1d0a-4cdf-aea6-7025bca3a403",
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
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+ "year": "2015",
+ "owner": "MODENA"
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+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
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+ "guideline": [
+ "WST-1"
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new file mode 100644
index 0000000..c07cce6
--- /dev/null
+++ b/src/enm/study-XLSX-e899dba3-4875-4fb2-b752-6792181138b8.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-e899dba3-4875-4fb2-b752-6792181138b8",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d7934c3e-9eac-34bc-8c60-4cf0c46e92a3"
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+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "008",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "008",
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+ "Shape"
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+ },
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diff --git a/src/enm/study-XLSX-e8f808ee-cc98-4134-93e3-88d313d6ac48.json b/src/enm/study-XLSX-e8f808ee-cc98-4134-93e3-88d313d6ac48.json
new file mode 100644
index 0000000..cc53359
--- /dev/null
+++ b/src/enm/study-XLSX-e8f808ee-cc98-4134-93e3-88d313d6ac48.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-e8f808ee-cc98-4134-93e3-88d313d6ac48",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-adf890e9-3623-3a0e-b601-11f8e5e2f3cb"
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+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
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+ "citation": {
+ "title": "018",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "018",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
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diff --git a/src/enm/study-XLSX-e9bee75e-8347-4f49-ab8d-f76ca4a4369c.json b/src/enm/study-XLSX-e9bee75e-8347-4f49-ab8d-f76ca4a4369c.json
new file mode 100644
index 0000000..d4165b8
--- /dev/null
+++ b/src/enm/study-XLSX-e9bee75e-8347-4f49-ab8d-f76ca4a4369c.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-e9bee75e-8347-4f49-ab8d-f76ca4a4369c",
+ "owner": {
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+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
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+ "year": "2015",
+ "owner": "MODENA"
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+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "027",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
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+ "reliability": {
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diff --git a/src/enm/study-XLSX-f1d098ec-d929-4410-a1af-f720036f834d.json b/src/enm/study-XLSX-f1d098ec-d929-4410-a1af-f720036f834d.json
new file mode 100644
index 0000000..af34874
--- /dev/null
+++ b/src/enm/study-XLSX-f1d098ec-d929-4410-a1af-f720036f834d.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-f1d098ec-d929-4410-a1af-f720036f834d",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-7394378e-b717-3418-a3f7-27db3cbbd8d0"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "033",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "033",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "A549",
+ "Dispersion protocol": "Tip",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 390.72
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 3988.011
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 143.892
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f2524359-9748-4797-95f8-9064b832b153.json b/src/enm/study-XLSX-f2524359-9748-4797-95f8-9064b832b153.json
new file mode 100644
index 0000000..04188e2
--- /dev/null
+++ b/src/enm/study-XLSX-f2524359-9748-4797-95f8-9064b832b153.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f2524359-9748-4797-95f8-9064b832b153",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d3a9ce39-6c15-3e4b-a5ce-5ea23e45ff16"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "113",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "113",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ },
+ "result": {
+ "unit": "(m2/g)",
+ "loValue": 189.16
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f3369e08-9403-44dd-b930-7e6ad8debaa8.json b/src/enm/study-XLSX-f3369e08-9403-44dd-b930-7e6ad8debaa8.json
new file mode 100644
index 0000000..c11d851
--- /dev/null
+++ b/src/enm/study-XLSX-f3369e08-9403-44dd-b930-7e6ad8debaa8.json
@@ -0,0 +1,63 @@
+{
+ "uuid": "XLSX-f3369e08-9403-44dd-b930-7e6ad8debaa8",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-a44564c5-1458-3e3b-aca7-d63f5221d2a8"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "183",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "183",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Tip"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 106
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 178
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f34d9633-f73f-454a-91ea-ef756cb9ade4.json b/src/enm/study-XLSX-f34d9633-f73f-454a-91ea-ef756cb9ade4.json
new file mode 100644
index 0000000..026cfa6
--- /dev/null
+++ b/src/enm/study-XLSX-f34d9633-f73f-454a-91ea-ef756cb9ade4.json
@@ -0,0 +1,72 @@
+{
+ "uuid": "XLSX-f34d9633-f73f-454a-91ea-ef756cb9ade4",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-2ca46b71-491d-3e73-9b4c-3fb885705274"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "157",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "PC_GRANULOMETRY_SECTION",
+ "term": "http://purl.obolibrary.org/obo/CHMO_0002119",
+ "title": "4.5 Particle size distribution (Granulometry)"
+ },
+ "endpoint": "157",
+ "guideline": [
+ "TEM"
+ ]
+ },
+ "parameters": {
+ "Dispersion protocol": "Vortexing"
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
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+ },
+ "effects": [
+ {
+ "endpoint": "PRIMARY SIZE 1ST DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "PRIMARY SIZE 2ND DIMENSION",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 100
+ }
+ },
+ {
+ "endpoint": "SIZE IN SITU",
+ "conditions": {
+ },
+ "result": {
+ "unit": "nm",
+ "loValue": 465
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f39a60aa-b599-4d09-b344-2b6480f14720.json b/src/enm/study-XLSX-f39a60aa-b599-4d09-b344-2b6480f14720.json
new file mode 100644
index 0000000..1d9b9e7
--- /dev/null
+++ b/src/enm/study-XLSX-f39a60aa-b599-4d09-b344-2b6480f14720.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f39a60aa-b599-4d09-b344-2b6480f14720",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-190fb54d-9b65-3d58-b65e-b3aae9a1f182"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "154",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "154",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Irregular euhedral"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.36
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f40c9a22-a2d2-410b-99d2-fec1b44bcf0a.json b/src/enm/study-XLSX-f40c9a22-a2d2-410b-99d2-fec1b44bcf0a.json
new file mode 100644
index 0000000..fc3f5f7
--- /dev/null
+++ b/src/enm/study-XLSX-f40c9a22-a2d2-410b-99d2-fec1b44bcf0a.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-f40c9a22-a2d2-410b-99d2-fec1b44bcf0a",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-3ff81e94-3d5d-3e58-a761-b0bd7c94de3b"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "106",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0003009_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0003009",
+ "title": "BAO_0003009 Cell Viability Assay"
+ },
+ "endpoint": "106",
+ "guideline": [
+ "WST-1"
+ ]
+ },
+ "parameters": {
+ "Cell line": "A549",
+ "Dispersion protocol": "Vortexing",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 76.229
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 143.961
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 2.709
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f4aabeaa-a7f4-4dfe-ab3b-f554a313d175.json b/src/enm/study-XLSX-f4aabeaa-a7f4-4dfe-ab3b-f554a313d175.json
new file mode 100644
index 0000000..09fc445
--- /dev/null
+++ b/src/enm/study-XLSX-f4aabeaa-a7f4-4dfe-ab3b-f554a313d175.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f4aabeaa-a7f4-4dfe-ab3b-f554a313d175",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-3dac4f9c-8c47-3085-9781-e70583adb12f"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "167",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "167",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Mainly 2 euhedral morphologies: aspect ratio of 1 (20–250 nm and 400 nm) and 2:7,5 (50-350 nm)"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.68
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f4ba2094-beba-4eb3-9a75-1d0955c3af17.json b/src/enm/study-XLSX-f4ba2094-beba-4eb3-9a75-1d0955c3af17.json
new file mode 100644
index 0000000..988a222
--- /dev/null
+++ b/src/enm/study-XLSX-f4ba2094-beba-4eb3-9a75-1d0955c3af17.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f4ba2094-beba-4eb3-9a75-1d0955c3af17",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-5e44448d-216f-3b91-891a-a7e1de030a13"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "186",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "186",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "equi-axed and rounded, or slightly elongated"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.6
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f5800c94-652b-419f-b812-9446748af04c.json b/src/enm/study-XLSX-f5800c94-652b-419f-b812-9446748af04c.json
new file mode 100644
index 0000000..c5d6e67
--- /dev/null
+++ b/src/enm/study-XLSX-f5800c94-652b-419f-b812-9446748af04c.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f5800c94-652b-419f-b812-9446748af04c",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-2acfa382-5109-3e49-9fd4-ef8d139be4b2"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "103",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "103",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f596b79d-58bd-4c59-8255-cb51aa2ffbec.json b/src/enm/study-XLSX-f596b79d-58bd-4c59-8255-cb51aa2ffbec.json
new file mode 100644
index 0000000..3670f8e
--- /dev/null
+++ b/src/enm/study-XLSX-f596b79d-58bd-4c59-8255-cb51aa2ffbec.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f596b79d-58bd-4c59-8255-cb51aa2ffbec",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-d3a9ce39-6c15-3e4b-a5ce-5ea23e45ff16"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "113",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "113",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -47.5
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f5ba28f1-d236-415d-af07-6ffe7b15585e.json b/src/enm/study-XLSX-f5ba28f1-d236-415d-af07-6ffe7b15585e.json
new file mode 100644
index 0000000..026de90
--- /dev/null
+++ b/src/enm/study-XLSX-f5ba28f1-d236-415d-af07-6ffe7b15585e.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-f5ba28f1-d236-415d-af07-6ffe7b15585e",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-adf890e9-3623-3a0e-b601-11f8e5e2f3cb"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "013",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "013",
+ "guideline": [
+ "LDH"
+ ]
+ },
+ "parameters": {
+ "Cell line": "A549",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "EC25",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 1486.452
+ }
+ },
+ {
+ "endpoint": "EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 2076.856
+ }
+ },
+ {
+ "endpoint": "SLOPE EC50",
+ "conditions": {
+ },
+ "result": {
+ "unit": "ug/ml",
+ "loValue": 23.616
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f61dd9c6-563c-40a5-8fcc-52c9f4ad7590.json b/src/enm/study-XLSX-f61dd9c6-563c-40a5-8fcc-52c9f4ad7590.json
new file mode 100644
index 0000000..db56049
--- /dev/null
+++ b/src/enm/study-XLSX-f61dd9c6-563c-40a5-8fcc-52c9f4ad7590.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f61dd9c6-563c-40a5-8fcc-52c9f4ad7590",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-3ff81e94-3d5d-3e58-a761-b0bd7c94de3b"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "107",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "107",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -40
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f680f3e9-24d8-482c-ac04-0ee2884348a4.json b/src/enm/study-XLSX-f680f3e9-24d8-482c-ac04-0ee2884348a4.json
new file mode 100644
index 0000000..778cfee
--- /dev/null
+++ b/src/enm/study-XLSX-f680f3e9-24d8-482c-ac04-0ee2884348a4.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f680f3e9-24d8-482c-ac04-0ee2884348a4",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-945d75a3-50b7-3655-8979-376d39096378"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "031",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "031",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "highly bend"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 79
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f752a9e6-816d-4d83-8211-55fef5b0d24e.json b/src/enm/study-XLSX-f752a9e6-816d-4d83-8211-55fef5b0d24e.json
new file mode 100644
index 0000000..a30e485
--- /dev/null
+++ b/src/enm/study-XLSX-f752a9e6-816d-4d83-8211-55fef5b0d24e.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f752a9e6-816d-4d83-8211-55fef5b0d24e",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-0d71a921-0e8d-3f25-8deb-20478b7e884b"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "127",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ZETA_POTENTIAL_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1302",
+ "title": "4.29 Nanomaterial zeta potential"
+ },
+ "endpoint": "127",
+ "guideline": [
+ "Zeta Potential"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "ZETA POTENTIAL",
+ "conditions": {
+ },
+ "result": {
+ "unit": "mV",
+ "loValue": -32
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f861ae7e-cfc8-4406-b8c1-2bab45c9be8f.json b/src/enm/study-XLSX-f861ae7e-cfc8-4406-b8c1-2bab45c9be8f.json
new file mode 100644
index 0000000..01c8a62
--- /dev/null
+++ b/src/enm/study-XLSX-f861ae7e-cfc8-4406-b8c1-2bab45c9be8f.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f861ae7e-cfc8-4406-b8c1-2bab45c9be8f",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-190fb54d-9b65-3d58-b65e-b3aae9a1f182"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "154",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "SPECIFIC_SURFACE_AREA_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_1235",
+ "title": "4.28 Nanomaterial specific surface area"
+ },
+ "endpoint": "154",
+ "guideline": [
+ "SPECIFIC SURFACE AREA"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "SPECIFIC_SURFACE_AREA",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 99
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f9dc91ff-8f1d-4f73-962d-30cc1fe31699.json b/src/enm/study-XLSX-f9dc91ff-8f1d-4f73-962d-30cc1fe31699.json
new file mode 100644
index 0000000..7a37e8c
--- /dev/null
+++ b/src/enm/study-XLSX-f9dc91ff-8f1d-4f73-962d-30cc1fe31699.json
@@ -0,0 +1,696 @@
+{
+ "uuid": "XLSX-f9dc91ff-8f1d-4f73-962d-30cc1fe31699",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-aacdfad8-f3d3-39f2-b662-0d8084e283ef"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "",
+ "guideline": [
+ "ELISA / TNF-α release in culture medium"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "Y",
+ "CLO_0000031": "HMDM (primary cells)",
+ "CLO_0000031 EFO_0004443": "ATCC",
+ "Cell culture conditions - Serum": "FBS (Gibco/413105K) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": 0.1,
+ "Cell line/Type - Full name": "human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "N",
+ "NPO_1961": "N",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, RNBB2729 "
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 3.092
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 28.881
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 16.978
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 6.298
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.61
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.562
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.905
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 10.723
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 0.874
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.347
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
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+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
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+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 13.103
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
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+ "unit": "h"
+ }
+ },
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
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+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
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+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
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+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
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+ "unit": "h"
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+ },
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
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+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
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+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 16.807
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 10.86
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
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+ "loValue": 21.04
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
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+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
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+ "unit": "h"
+ }
+ },
+ "result": {
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+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 29.266
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 29.534
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 25.48
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 22.79
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 21.142
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-f9df1a98-6f38-473a-a70f-80dcdf8fa5be.json b/src/enm/study-XLSX-f9df1a98-6f38-473a-a70f-80dcdf8fa5be.json
new file mode 100644
index 0000000..6f74bb6
--- /dev/null
+++ b/src/enm/study-XLSX-f9df1a98-6f38-473a-a70f-80dcdf8fa5be.json
@@ -0,0 +1,53 @@
+{
+ "uuid": "XLSX-f9df1a98-6f38-473a-a70f-80dcdf8fa5be",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-7e2b0550-595b-3427-b6f3-b84211a5c402"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "019",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "P-CHEM",
+ "category": {
+ "code": "ASPECT_RATIO_SHAPE_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo/NPO_274",
+ "title": "4.27 Nanomaterial aspect ratio/shape"
+ },
+ "endpoint": "019",
+ "guideline": [
+ "Shape"
+ ]
+ },
+ "parameters": {
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": "Mainly euhedral (some elongated or sub-spherical)"
+ },
+ "effects": [
+ {
+ "endpoint": "ASPECT RATIO",
+ "conditions": {
+ },
+ "result": {
+ "unit": null,
+ "loValue": 1.1
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-fa433d53-df49-4420-854a-fd59b58d39c5.json b/src/enm/study-XLSX-fa433d53-df49-4420-854a-fd59b58d39c5.json
new file mode 100644
index 0000000..b72311b
--- /dev/null
+++ b/src/enm/study-XLSX-fa433d53-df49-4420-854a-fd59b58d39c5.json
@@ -0,0 +1,696 @@
+{
+ "uuid": "XLSX-fa433d53-df49-4420-854a-fd59b58d39c5",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-ffd24485-3b05-3afe-b6ff-547800723f71"
+ },
+ "company": {
+ "uuid": "XLSX-4bb81f08-059d-32ad-b5fd-71c6bcc6e0db",
+ "name": "FP7 MARINA"
+ }
+ },
+ "citation": {
+ "title": "http://dx.doi.org/10.1371/journal.pone.0127174",
+ "year": "2015",
+ "owner": "P32 - KI"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "BAO_0002993_SECTION",
+ "term": "http://purl.obolibrary.org/obo/BAO_0002993",
+ "title": "BAO_0002993 Cytotoxicity Assay"
+ },
+ "endpoint": "",
+ "guideline": [
+ "ELISA / TNF-α release in culture medium"
+ ]
+ },
+ "parameters": {
+ "CHMO:0002774": "Y",
+ "CLO_0000031": "HMDM (primary cells)",
+ "CLO_0000031 EFO_0004443": "ATCC",
+ "Cell culture conditions - Serum": "FBS (Gibco/413105K) ",
+ "Cell culture conditions - Serum concentration in growth medium": 0.1,
+ "Cell culture conditions - Serum concentration in treatment medium": 0.1,
+ "Cell line/Type - Full name": "human monocyte-derived macrophages (HMDM)",
+ "Dispersion agent": "water with 0,05% BSA",
+ "NPO_1952": "N",
+ "NPO_1961": "N",
+ "NPO_1969 OBI_0000272": "NANOGENOTOX Dispersion protocol (http://www.nanogenotox.eu/files/PDF/web%20nanogenotox%20dispersion%20protocol.pdf) ",
+ "OBI_0001911 BAO_0000114": "RPMI (Sigma, RNBB2729 "
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
+ "r_purposeFlag": null,
+ "r_studyResultType": "experimental result",
+ "r_value": null
+ },
+ "interpretation": {
+ "result": null
+ },
+ "effects": [
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.893
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 18.514
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 18.428
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 15.693
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 16.034
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 16.45
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 16.752
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 1",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 16.306
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": -0.343
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 11.593
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 8.816
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 6.91
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 5.42
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 5.461
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 6.527
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 2",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 0.599
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.189
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 3.195
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.978
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.9
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 2.014
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.952
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 1.467
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 3",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 0.401
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 0,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 9.502
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 1,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 7.576
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 5,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 7.826
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 10,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 10.336
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 25,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 10.84
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 50,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 10.924
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 75,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 11.36
+ }
+ },
+ {
+ "endpoint": "TNF-α (ng/ml)",
+ "conditions": {
+ "Concentration": {
+ "loQualifier": "=",
+ "loValue": 100,
+ "unit": "µg/ml"
+ },
+ "Replicate": "Replicate 4",
+ "Time point": {
+ "loQualifier": "=",
+ "loValue": 24,
+ "unit": "h"
+ }
+ },
+ "result": {
+ "unit": "ng/ml",
+ "loValue": 7.389
+ }
+ }
+ ]
+}
diff --git a/src/enm/study-XLSX-fb1ee400-bfaa-4ac1-bd6f-801e8ead9842.json b/src/enm/study-XLSX-fb1ee400-bfaa-4ac1-bd6f-801e8ead9842.json
new file mode 100644
index 0000000..c9a8046
--- /dev/null
+++ b/src/enm/study-XLSX-fb1ee400-bfaa-4ac1-bd6f-801e8ead9842.json
@@ -0,0 +1,75 @@
+{
+ "uuid": "XLSX-fb1ee400-bfaa-4ac1-bd6f-801e8ead9842",
+ "owner": {
+ "substance": {
+ "uuid": "XLSX-673c8355-a823-3bf2-a319-0d8af43e4d90"
+ },
+ "company": {
+ "uuid": "XLSX-c4568d50-2e06-3173-95d2-01adb74e6632",
+ "name": "MODENA"
+ }
+ },
+ "citation": {
+ "title": "148",
+ "year": "2015",
+ "owner": "MODENA"
+ },
+ "protocol": {
+ "topcategory": "TOX",
+ "category": {
+ "code": "NPO_1709_SECTION",
+ "term": "http://purl.bioontology.org/ontology/npo#NPO_1709",
+ "title": "NPO_1709 LDH Release Assay"
+ },
+ "endpoint": "148",
+ "guideline": [
+ "LDH"
+ ]
+ },
+ "parameters": {
+ "Cell line": "THP-1 macrophage",
+ "Dispersion protocol": "Bath",
+ "Exposure duration,h": 24,
+ "Serum concentration,%": 0.1
+ },
+ "reliability": {
+ "r_isRobustStudy": "false",
+ "r_isUsedforClassification": "false",
+ "r_isUsedforMSDS": "false",
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