diff options
| author | Christoph Helma <helma@in-silico.ch> | 2017-02-09 14:25:19 +0100 |
|---|---|---|
| committer | Christoph Helma <helma@in-silico.ch> | 2017-02-09 14:25:19 +0100 |
| commit | db82eef974b8783c40e7daa504feead3f555fdb8 (patch) | |
| tree | a9bf02a6455cb2cb399b15bed3fcd759cb2b3448 | |
| parent | 7ad7c10c1e708f6b5a3473de24dbeab03d0b74a3 (diff) | |
directories restructured
| -rw-r--r-- | Makefile | 83 | ||||
| -rw-r--r-- | TODO | 46 | ||||
| -rw-r--r-- | data/Copy of NOAEL-LOAEL - rat_chron.csv | 579 | ||||
| -rw-r--r-- | data/Copy of NOAEL-LOAEL.xlsx | bin | 0 -> 245908 bytes | |||
| -rw-r--r-- | data/NOAEL-LOAEL_SMILES_rat_chron.csv | 579 | ||||
| -rw-r--r-- | data/NOAEL-LOAEL_dv.xlsx | bin | 0 -> 325917 bytes | |||
| -rw-r--r-- | data/common.csv | 59 | ||||
| -rw-r--r-- | data/functional-groups-smarts.csv | 35 | ||||
| -rw-r--r-- | data/functional-groups.txt (renamed from functional-groups.txt) | 0 | ||||
| -rw-r--r-- | data/functional-groups.yaml (renamed from functional-groups.yaml) | 0 | ||||
| -rw-r--r-- | data/mazzatorta.csv~ | 568 | ||||
| -rw-r--r-- | data/misclassifications.csv | 14 | ||||
| -rw-r--r-- | data/swiss.csv | 2 | ||||
| -rw-r--r-- | data/swiss.csv~ | 494 | ||||
| -rw-r--r-- | data/test.csv~ (renamed from data/test.csv) | 0 | ||||
| -rw-r--r-- | data/training.csv~ (renamed from data/training.csv) | 0 | ||||
| -rw-r--r-- | figures/crossvalidation.pdf (renamed from figure/crossvalidation.pdf) | bin | 30511 -> 30511 bytes | |||
| -rw-r--r-- | figures/dataset-variability.pdf (renamed from figure/dataset-variability.pdf) | bin | 10283 -> 10283 bytes | |||
| -rw-r--r-- | figures/functional-groups.pdf (renamed from figure/functional-groups.pdf) | bin | 6496 -> 6496 bytes | |||
| -rw-r--r-- | figures/pc-small-compounds-highlighted.png (renamed from figure/pc-small-compounds-highlighted.png) | bin | 499180 -> 499180 bytes | |||
| -rw-r--r-- | figures/test-correlation.pdf (renamed from figure/test-correlation.pdf) | bin | 7512 -> 7512 bytes | |||
| -rw-r--r-- | figures/test-prediction.pdf (renamed from figure/test-prediction.pdf) | bin | 10719 -> 10719 bytes | |||
| -rw-r--r-- | loael.md | 2 | ||||
| -rw-r--r-- | references.bibtex | 10 | ||||
| -rwxr-xr-x | scripts/correct-predictions.R | 1 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/create-median-correlation.rb (renamed from create-median-correlation.rb) | 0 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/create-test.rb (renamed from create-test.rb) | 4 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/create-training.rb (renamed from create-training.rb) | 4 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/crossvalidation-plots.R (renamed from crossvalidation-plots.R) | 0 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/crossvalidation.rb (renamed from crossvalidation.rb) | 0 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/dataset-variability.R (renamed from dataset-variability.R) | 0 | ||||
| -rwxr-xr-x | scripts/functional-groups-smarts.rb | 14 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/functional-groups.R (renamed from functional-groups.R) | 0 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/functional-groups.rb (renamed from functional-groups.rb) | 0 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/functional-groups4R.rb (renamed from functional-groups4R.rb) | 0 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/include.rb (renamed from include.rb) | 0 | ||||
| -rwxr-xr-x | scripts/mazzatorta-unique-smiles.rb | 17 | ||||
| -rwxr-xr-x | scripts/misclassification-predictions.rb | 15 | ||||
| -rwxr-xr-x | scripts/misclassifications.rb | 61 | ||||
| -rwxr-xr-x | scripts/noael_loael2mmol.rb | 19 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/test-correlation-plot.R (renamed from test-correlation-plot.R) | 0 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/test-prediction-plot.R (renamed from test-prediction-plot.R) | 0 | ||||
| -rwxr-xr-x | scripts/test-prediction.R | 15 | ||||
| -rwxr-xr-x[-rw-r--r--] | scripts/test-validation.rb (renamed from test-validation.rb) | 0 | ||||
| -rw-r--r-- | unique-smiles.rb | 19 |
45 files changed, 2530 insertions, 110 deletions
@@ -1,9 +1,9 @@ # Variables -datasets = data/median-correlation.csv data/test.csv data/training.csv data/mazzatorta.csv data/swiss.csv data/test.json data/training.json data/mazzatorta.json data/swiss.json +datasets = data/median-correlation.csv data/test_log10.csv data/training_log10.csv data/mazzatorta_log10.csv data/swiss_log10.csv data/test.json data/training.json data/mazzatorta.json data/swiss.json crossvalidations = data/training-cv-0.csv data/training-cv-1.csv data/training-cv-2.csv validations = data/training-test-predictions.csv $(crossvalidations) data/misclassifications.csv -figures = figure/functional-groups.pdf figure/test-prediction.pdf figure/test-correlation.pdf figure/crossvalidation.pdf figure/dataset-variability.pdf +figures = figures/functional-groups.pdf figures/test-prediction.pdf figures/test-correlation.pdf figures/crossvalidation.pdf figures/dataset-variability.pdf # Paper @@ -11,81 +11,82 @@ loael.pdf: loael.md references.bibtex pandoc -r markdown+simple_tables+table_captions+yaml_metadata_block -s -S --bibliography=references.bibtex --latex-engine=pdflatex --filter pandoc-crossref --filter pandoc-citeproc -o loael.pdf loael.md loael.md: loael.Rmd $(figures) $(datasets) $(validations) - Rscript --vanilla -e "library(knitr); knit('loael.Rmd');" + scripts/--vanilla -e "library(knitr); knit('loael.Rmd');" loael.docx: loael.md pandoc --filter pandoc-crossref --filter pandoc-citeproc loael.md -s -o loael.docx # Figures -figure/functional-groups.pdf: data/functional-groups-reduced4R.csv functional-groups.R - Rscript functional-groups.R +figures/functional-groups.pdf: data/functional-groups-reduced4R.csv + scripts/functional-groups.R -figure/dataset-variability.pdf: data/mazzatorta.csv data/swiss.csv dataset-variability.R - Rscript dataset-variability.R +figures/dataset-variability.pdf: data/mazzatorta.csv data/swiss.csv + scripts/dataset-variability.R -figure/crossvalidation.pdf: $(crossvalidations) - Rscript crossvalidation-plots.R +figures/crossvalidation.pdf: $(crossvalidations) + scripts/crossvalidation-plots.R -figure/test-prediction.pdf: data/training-test-predictions.csv data/median-correlation.csv test-prediction-plot.R - Rscript test-prediction-plot.R +figures/test-prediction.pdf: data/training-test-predictions.csv data/median-correlation.csv + scripts/test-prediction-plot.R -figure/test-correlation.pdf: data/training-test-predictions.csv data/median-correlation.csv test-correlation-plot.R - Rscript test-correlation-plot.R +figures/test-correlation.pdf: data/training-test-predictions.csv data/median-correlation.csv + scripts/test-correlation-plot.R # Validations -data/misclassifications.csv: misclassifications.rb data/training-test-predictions.csv - ruby misclassifications.rb +data/misclassifications.csv: data/training-test-predictions.csv + scripts/misclassifications.rb -data/training-test-predictions.csv: test-validation.rb data/test.csv data/training.csv - ruby test-validation.rb training.csv +data/training-test-predictions.csv: data/test_log10.csv data/training_log10.csv + scripts/test-validation.rb training.csv -data/training-cv-0.csv: crossvalidation.rb data/training.csv - ruby crossvalidation.rb training.csv 0 +data/training-cv-0.csv: data/training_log10.csv + scripts/crossvalidation.rb training.csv 0 -data/training-cv-1.csv: crossvalidation.rb data/training.csv - ruby crossvalidation.rb training.csv 1 +data/training-cv-1.csv: data/training_log10.csv + scripts/crossvalidation.rb training.csv 1 -data/training-cv-2.csv: crossvalidation.rb data/training.csv - ruby crossvalidation.rb training.csv 2 +data/training-cv-2.csv: data/training_log10.csv + scripts/crossvalidation.rb training.csv 2 # Datasets -data/functional-groups-reduced4R.csv: data/functional-groups-reduced.csv functional-groups4R.rb - ruby functional-groups4R.rb +data/functional-groups-reduced4R.csv: data/functional-groups-reduced.csv + scripts/functional-groups4R.rb # Medians for dataset correlation -data/median-correlation.csv: create-median-correlation.rb data/mazzatorta.csv data/swiss.csv - ruby create-median-correlation.rb +data/median-correlation.csv: data/mazzatorta.csv data/swiss.csv + scripts/create-median-correlation.rb # Test set -data/test.csv: create-test.rb data/mazzatorta.csv data/swiss.csv - ruby create-test.rb +data/test_log10.csv: data/mazzatorta_log10.csv data/swiss_log10.csv + scripts/create-test.rb data/test.json: data/mazzatorta.json cp data/mazzatorta.json data/test.json # Combined training set -data/training.csv: create-training.rb data/mazzatorta.csv data/swiss.csv - ruby create-training.rb +data/training_log10.csv: data/mazzatorta_log10.csv data/swiss_log10.csv + scripts/create-training.rb data/training.json: data/mazzatorta.json cp data/mazzatorta.json data/training.json -# Datasets with unique smiles -data/mazzatorta.csv: unique-smiles.rb data/LOAEL_mg_corrected_smiles_mmol.csv - ruby unique-smiles.rb data/LOAEL_mg_corrected_smiles_mmol.csv "mazzatorta" +# -log10 transformations +data/mazzatorta_log10.csv: data/mazzatorta.csv + ../lazar/scripts/mmol2-log10.rb data/mazzatorta.csv -data/mazzatorta.json: data/LOAEL_mg_corrected_smiles_mmol.json - cp data/LOAEL_mg_corrected_smiles_mmol.json data/mazzatorta.json +data/swiss_log10.csv: data/swiss.csv + ../lazar/scripts/mmol2-log10.rb data/swiss.csv -data/swiss.csv: unique-smiles.rb data/swissRat_chron_LOAEL_mmol.csv - ruby unique-smiles.rb data/swissRat_chron_LOAEL_mmol.csv "swiss" +# Datasets with unique smiles +data/mazzatorta.csv: data/LOAEL_mg_corrected_smiles_mmol.csv + scripts/mazzatorta-unique-smiles.rb data/LOAEL_mg_corrected_smiles_mmol.csv > data/mazzatorta.csv -data/swiss.json: data/swissRat_chron_LOAEL_mmol.json - cp data/swissRat_chron_LOAEL_mmol.json data/swiss.json +data/swiss.csv: data/NOAEL-LOAEL_SMILES_rat_chron.csv + scripts/noael_loael2mmol.rb data/NOAEL-LOAEL_SMILES_rat_chron.csv > data/swiss.csv clean: - rm figure/*pdf + rm figures/*pdf cd data && rm `ls -I "*LOAEL*" -I "*functional*" -I "*SMARTS*"` @@ -1,46 +0,0 @@ -# lazar - -#confidence intervals -TODO: github tags - -#try to increase predictive accuracies - -##radial svm (wores than pls) -#similarity threshold -#activity specific similarities -#uniquedescriptors -#random forests - -# gui -warning if query compound contains new functional groups - -# analysis -#predictions fit experimental data - -#only combined dataset (training) -#combined -> training dataset - -#functional groups: remove, minfreq - -smarts f functional groups - -#error band (experimental variability) for fig 7 - -# paper -#datasets: - #rat chronic column - #preprocessing remove first sentence - -results: - #CheSMapper remove text, figures - #fig 2 smiles -> smarts, leave out? - - #variability from paolos paper - #https://en.wikipedia.org/wiki/Root_mean_square_deviation - #When the RMSD is normalized by the mean measured value, is usually called coefficient of variation of the RMSD, CV(RMSD). It is analogous to the coefficient of variation with the RMSD taking the place of the standard deviation. - -discussion: mispredictions - -#AD definition - -#line nrs in pdf diff --git a/data/Copy of NOAEL-LOAEL - rat_chron.csv b/data/Copy of NOAEL-LOAEL - rat_chron.csv new file mode 100644 index 0000000..874c76b --- /dev/null +++ b/data/Copy of NOAEL-LOAEL - rat_chron.csv @@ -0,0 +1,579 @@ +ID NOAEL,ID Stoff,compound,author,study year,evaluator,evaluation year,class,function,CASNR,CAS name,SMILES,species,n,regimen,study type,Np_conc,Np_dose,Lp_conc,Lp_dose
+6901,2233,"1,4-Dimethylnaphtalene",Mallet,2011,DAR,2012,,,571-58-4,,,rat,85,fc; food concentration,104 weeks,150,10,500,27
+5829,410,2-(1-naphthyl)acetic acid,Drummond,1996,DAR,2010,auxin,plant growth regulator,86-87-3,1-naphthaleneacetic acid,O=C(O)CC2=CC=CC1=CC=CC=C12,rat,80,fc; food concentration,104 weeks,1000,43.79999924,5000,224.5
+5386,216,"2,4-D",Hansen,1971,JMPR,1996,"alkanoic acid, aryloxy",herbicide,94-75-7,"(2,4-dichlorophenoxy)acetic acid",ClC1=CC(Cl)=C(OCC(O)=O)C=C1,rat,25,fc; food concentration,104 weeks,625,31,1250,62
+5387,216,"2,4-D",Serota,1986,JMPR,1996,"alkanoic acid, aryloxy",herbicide,94-75-7,"(2,4-dichlorophenoxy)acetic acid",ClC1=CC(Cl)=C(OCC(O)=O)C=C1,rat,50,fd; food dose,104 weeks,0,1,0,5
+5388,216,"2,4-D",Jeffries,1995,JMPR,1996,"alkanoic acid, aryloxy",herbicide,94-75-7,"(2,4-dichlorophenoxy)acetic acid",ClC1=CC(Cl)=C(OCC(O)=O)C=C1,rat,50,fd; food dose,104 weeks,0,5,0,75
+880,60,Abamectin,Gordon,1985,DAR,2006,avermectin,Insecticide,71751-41-2,avermectin B1a + avermectin B1b,B1b: C/C(C(C(/C=C/C=C4/C5(O)C(C(O)C(C)=CC5C6=O)OC4)C)OC2CC(OC)C(OC7CC(OC)C(O)C(C)O7)C(C)O2)=C\CC1CC(O6)CC3(OC(C(C)C)C(C)C=C3)O1 ; B1a: C/C(C(C(/C=C/C=C4/C5(O)C(C(O)C(C)=CC5C6=O)OC4)C)OC2CC(OC)C(OC7CC(OC)C(O)C(C)O7)C(C)O2)=C\CC1CC(O6)CC3(OC(C(CC)C)C(C)C=C3,rat,50,fd; food dose,104 weeks,0,1.5,0,2
+5083,266,Acephat,Auletta,1981,JMPR,2002,organophosphorus,insecticide,30560-19-1,N-[methoxy(methylthio)phosphinoyl]acetamide,O=P(SC)(OC)NC(C)=O,rat,75,fc; food concentration,120 weeks,5,0.25,50,2.5
+881,340,Acequinocyl,Inoue,1997,DAR,2005,quinone,acaricide,57960-19-7,"2-(acetyloxy)-3-dodecyl-1,4-naphthalenedione",O=C2C(CCCCCCCCCCCC)=C(OC(C)=O)C(C1=CC=CC=C12)=O,rat,50,fc; food concentration,104 weeks,50,2.299999952,200,9
+882,164,Acetamiprid,Hatch,1999,JMPR,2011,pyridine,insecticide,135410-20-7,(E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine,ClC1=CC=C(CN(C)/C(C)=N/C#N)C=N1,rat,60,fc; food concentration,104 weeks,160,7.099999905,400,17.5
+883,1,Acetochlor,Naylor,1986,DAR,2006,chloroacetanilide,herbicide,34256-82-1,2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)acetamide,O=C(N(COCC)C1=C(CC)C=CC=C1C)CCl,rat,60,fc; food concentration,104 weeks,200,9.399999619,1000,47.5
+2555,1,Acetochlor,Ahmed,1983,DAR,2006,chloroacetanilide,herbicide,34256-82-1,2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)acetamide,O=C(N(COCC)C1=C(CC)C=CC=C1C)CCl,rat,60,fc; food concentration,104 weeks,500,22,1500,69
+2556,1,Acetochlor,Broadmeadow,1989,DAR,2006,chloroacetanilide,herbicide,34256-82-1,2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)acetamide,O=C(N(COCC)C1=C(CC)C=CC=C1C)CCl,rat,50,fc; food concentration,104 weeks,175,6.369999886,1750,66.90000153
+884,184,Acibenzolar-S-methyl,Anonymous,1996,DAR,2013,others,fungicide,135158-54-2,"1,2,3-benzothiadiazole-7-thiocarbxylic acid S-methyl ester",CSC(C1=C2C(N=NS2)=CC=C1)=O,rat,,fc; food concentration,104 weeks,200,7.769999981,2500,96.90000153
+885,33,Aclonifen,Kirsch,1989,DAR,2006,diphenyl ether,herbicide,74070-46-5,2-chloro-6-nitro-3-phenoxybenzenamine,NC1=C(C(OC2=CC=CC=C2)=CC=C1[N+]([O-])=O)Cl,rat,50,fc; food concentration,104 weeks,40,1.600000024,200,8
+2565,33,Aclonifen,Wason,2004,DAR,2006,diphenyl ether,herbicide,74070-46-5,2-chloro-6-nitro-3-phenoxybenzenamine,NC1=C(C(OC2=CC=CC=C2)=CC=C1[N+]([O-])=O)Cl,rat,60,fc; food concentration,104 weeks,200,7.599999905,1600,62
+2505,130,Acrinathrin,Cooper,2004,DAR,2007,pyrethroid,acaricide,101007-06-1;103833-18-7unstatedstereochemistry,"2,2-dimethyl-3-[3-oxo-3-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-1-propenyl]cyclopropanecarboxylate",FC(F)(F)C(C(F)(F)F)OC(/C=C\C1C(C)(C)C1C(OC(C#N)C2=CC=C(OC3=CC=CC=C3)C=C2)=O)=O,rat,60,fc; food concentration,104 weeks,30,1.600000024,150,8.100000381
+2567,130,Acrinathrin,Vallet,1991,DAR,2007,pyrethroid,acaricide,101007-06-1;103833-18-7unstatedstereochemistry,"2,2-dimethyl-3-[3-oxo-3-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-1-propenyl]cyclopropanecarboxylate",FC(F)(F)C(C(F)(F)F)OC(/C=C\C1C(C)(C)C1C(OC(C#N)C2=CC=C(OC3=CC=CC=C3)C=C2)=O)=O,rat,50,fc; food concentration,104 weeks,90,4.599999905,0,0
+886,144,Alachlor,,,UK,1991,chloroacetanilide,herbicide,15972-60-8,"2-chloro-N-(2,6diethylphenyl)-N-(methoxymethyl)acetanilide",O=C(N(C1=C(CC)C=CC=C1CC)COC)CCl,rat,50,fd; food dose,104 weeks,0,0.5,0,2.5
+4797,144,Alachlor,,,UK,1991,chloroacetanilide,herbicide,15972-60-8,"2-chloro-N-(2,6diethylphenyl)-N-(methoxymethyl)acetanilide",O=C(N(C1=C(CC)C=CC=C1CC)COC)CCl,rat,50,fd; food dose,104 weeks,0,0,0,14
+4798,144,Alachlor,,,UK,1991,chloroacetanilide,herbicide,15972-60-8,"2-chloro-N-(2,6diethylphenyl)-N-(methoxymethyl)acetanilide",O=C(N(C1=C(CC)C=CC=C1CC)COC)CCl,rat,,fd; food dose,104 weeks,0,0,0,126
+4505,2159,alpha-Chlorohydrin,Weisburger,1981,USA,2006,,Rodenticide,96-24-2,"3-chloro-1,2-propanediol",,rat,,gc; gavage concentration,72 weeks,0,0,0,30
+4506,2159,alpha-Chlorohydrin,Sunahara,1993,USA,2006,,Rodenticide,96-24-2,"3-chloro-1,2-propanediol",,rat,,wc; water concentration,104 weeks,0,0,0,1.100000024
+6323,2055,Ametoctradin,not given,2008,EU,2012,,Fungicide,865318-97-4,"5-ethyl-6-octyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine",NC2=C(CCCCCCCC)C(CC)=NC1=NC=NN12,rat,60,fc; food concentration,104 weeks,15000,871,0,0
+5801,2160,Amicarbazone,,,USA,2005,triazolone,Herbicide,129909-90-6,"4-amino-N-(1,1-dimethylethyl)-4,5-dihydro-3-(1-methylethyl)-5-oxo-1H-1,2,4-triazole-1-carboxamide",,rat,,fc; food concentration,104 weeks,50,2.299999952,500,25.29999924
+888,198,Amidosulfuron,Dotti,1992,DAR,2006,"urea, sulfonyl",herbicide,120923-37-7,"N-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-N-methylmethanesulfonamide",O=S(N(C)S(C)(=O)=O)(NC(NC1=NC(OC)=CC(OC)=N1)=O)=O,rat,50,fc; food concentration,104 weeks,2000,97.80000305,10000,495.3999939
+2578,991,Aminopyralid,Johnson,2004,DAR,2008,pyridine,Herbicide,150114-71-9;566191-87-5(Kalium-),"4-amino-3,6-dichloro-2-pyridinecarboxylic acid",OC(C1=NC(Cl)=CC(N)=C1Cl)=O,rat,50,fd; food dose,104 weeks,0,500,0,1000
+2600,992,Amisulbrom,Blee,2005,DAR,2012,triazole,Fungicide,348635-87-0,"3-[(3-bromo-6-fluoro-2-methyl-1H-indol-1-yl)sulfonyl]-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide",CN(C)S(N(C=N3)N=C3S(N2C(C)=C(Br)C1=CC=C(F)C=C12)(=O)=O)(=O)=O,rat,70,fc; food concentration,104 weeks,200,11.10000038,2000,112
+890,212,Amitraz,Sutton,1973,JMPR,1998,amidine,insecticide,33089-61-1,"N'-(2,4-dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methylmethanimidamide",CN(/C=N/C(C=CC(C)=C2)=C2C)/C=N/C(C=CC(C)=C1)=C1C,rat,40,fc; food concentration,104 weeks,50,2.5,200,10
+891,75,Amitrol,Keller,1959,JMPR,1997,triazole,herbicide,61-82-5,"1H-1,2,4-triazol-3-amine",NC1=NNC=N1,rat,35,fc; food concentration,104 weeks,10,0.5,50,2.5
+5556,75,Amitrol,Steinhoff,1979,JMPR,1993,triazole,herbicide,61-82-5,"1H-1,2,4-triazol-3-amine",NC1=NNC=N1,rat,75,fc; food concentration,104 weeks,10,0.5,100,5
+892,218,Anilazin,Goodyer,1984,JMPR,1989,triazine,fungicide,101-05-3,"4,6-dichloro-N-(2-chlorophenyl)-1,3,5-triazin-2-amine",ClC2=C(C=CC=C2)NC1=NC(Cl)=NC(Cl)=N1,rat,60,fc; food concentration,104 weeks,2000,100,0,0
+893,402,Asulam,Hunter,1981,DAR,2006,carbamate,herbicide,3337-71-1,methyl [(4-aminophenyl)sulfonyl]carbamate,O=C(OC)NS(C1=CC=C(N)C=C1)(=O)=O,rat,75,fc; food concentration,104 weeks,1000,36,5000,180
+894,408,Atrazin,Mayhew,1986,JMPR,2007,triazine,herbicide,1912-24-9,"6-chloro-N-ethyl-N´-(1-methylethyl)-1,3,5-triazine-2,4-diamine",CCNC1=NC(NC(C)C)=NC(Cl)=N1,rat,70,fc; food concentration,104 weeks,25,1.5,50,3.099999905
+4771,408,Atrazin,,,JMPR,2007,triazine,herbicide,1912-24-9,"6-chloro-N-ethyl-N´-(1-methylethyl)-1,3,5-triazine-2,4-diamine",CCNC1=NC(NC(C)C)=NC(Cl)=N1,rat,,fc; food concentration,104 weeks,70,3.5,200,10
+4814,408,Atrazin,Rudzky,1991,JMPR,2007,triazine,herbicide,1912-24-9,"6-chloro-N-ethyl-N´-(1-methylethyl)-1,3,5-triazine-2,4-diamine",CCNC1=NC(NC(C)C)=NC(Cl)=N1,rat,50,fc; food concentration,104 weeks,50,2.299999952,500,23.60000038
+895,954,Azaconazol,,,UK,1988,azole,Fungicide,60207-31-0,"1-[[2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole",ClC1=C(C3(OCCO3)CN2C=NC=N2)C=CC(Cl)=C1,rat,,fc; food concentration,104 weeks,0,3.200000048,0,12.80000019
+3878,945,Azadirachtin,Kumar,2000,DAR,2009,others,Insecticide,11141-17-6,"dimethyl (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-",B: CC(OC1C(C(OC)=O)(COC2C(O)C(C56C(C7)OC(OC=C8)C8(O)C7C(C)5O6)(C)C3C(C(OC)=O)(O)OC4)C2C34C(OC(/C(C)=C/C)=O)C1)=O,rat,50,fc; food concentration,104 weeks,6400,448,0,0
+2629,980,Azimsulfuron,Inui,1994,DAR,2009,"urea, sulfonyl",Herbicide,120162-55-2,,COC1=NC(NC(NS(C2=C(C3=NN(C)N=N3)C=NN2C)(=O)=O)=O)=NC(OC)=C1,rat,,fc; food concentration,104 weeks,1000,43.29999924,5000,0
+896,422,Azinphos-methyl,Schmidt,1987,JMPR,2007,organophosphorus,insecticide,86-50-0,"0,0-dimethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] phosphorodithioate",S=P(OC)(OC)SCN1N=NC(C=CC=C2)=C2C1=O,rat,60,fc; food concentration,104 weeks,15,0.8999999762,45,2.700000048
+4916,433,Azocyclotin,Bomhard,1979,JMPR,2005,organotin,acaricide,41083-11-8,"1-(tricyclohexylstannyl)-1H-1,2,4-triazole",N4(N=CN=C4)[Sn](C2CCCCC2)(C3CCCCC3)C1CCCCC1,rat,50,fc; food concentration,104 weeks,5,0.2599999905,15,0.7900000215
+2614,298,Azoxystrobin,Milburn,1995,DAR,2009,strobilurin,fungicide,131860-33-8,methyl (E)-2-[[6-(2-cyanophenoxy)-4-pyrimidinyl]oxy]alpha-methoxymethylene)benzeneacetate,O=C(OC)/C(C1=CC=CC=C1OC2=CC(OC3=CC=CC=C3C#N)=NC=N2)=C/OC,rat,52,fc; food concentration,104 weeks,300,18.20000076,1500,82.40000153
+7080,2889,BAM,Wheldon,1971,EFSA,2005,,,,,NC(C1=C(Cl)C=CC=C1Cl)=O,rat,35,fc; food concentration,104 weeks,180,5.699999809,500,17.60000038
+6125,937,Beflubutamid,Barker,2000,DAR,2002,amide,Herbicide,113614-08-7,2-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(phenylmethyl)butanamide,FC(F)(F)C1=C(F)C=CC(OC(CC)C(NCC2=CC=CC=C2)=O)=C1,rat,60,,104 weeks,50,2.200000048,400,17.70000076
+898,435,Benalaxyl,Thompson,1983,JMPR,2005,phenylamide,fungicide,71626-11-4,"methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-DL-alaninate",COC(C(N(C2=C(C)C=CC=C2C)C(CC1=CC=CC=C1)=O)C)=O,rat,65,fc; food concentration,104 weeks,1000,44,0,0
+899,441,Bendiocarb,,,UK,2005,carbamate,insecticide,22781-23-3,"2,2-dimethyl-1,3-benzodioxol-4-yl methylcarbamate",CC2(C)OC1=CC=CC(OC(NC)=O)=C1O2,rat,,fc; food concentration,104 weeks,0,0.400000006,0,0.8000000119
+900,1041,Benfluralin,Moore,1996,DAR,2006,dinitroaniline,Herbicide,1861-40-1,"N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)benzenamine",CCN(CCCC)C1=C([N+]([O-])=O)C=C(C(F)(F)F)C=C1[N+]([O-])=O,rat,60,fc; food concentration,104 weeks,10,0.5,100,5.400000095
+901,76,Benfuracarb,Cox,1984,DAR,2005,carbamate,insecticide,82560-54-1,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl 2-methyl-4-(1-methylethyl)-7-oxo-8-oxa-3-thia-2,4-diazadecanoate",CCOC(CCN(C(C)C)SN(C)C(OC1=CC=CC2=C1OC(C)(C)C2)=O)=O,rat,50,fc; food concentration,104 weeks,100,5.5,0,11
+2396,76,Benfuracarb,Cox,1983,DAR,2005,carbamate,insecticide,82560-54-1,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl 2-methyl-4-(1-methylethyl)-7-oxo-8-oxa-3-thia-2,4-diazadecanoate",CCOC(CCN(C(C)C)SN(C)C(OC1=CC=CC2=C1OC(C)(C)C2)=O)=O,rat,10,fc; food concentration,52 weeks,200,11.89000034,400,24
+2641,76,Benfuracarb,Cox,1986,DAR,2005,carbamate,insecticide,82560-54-1,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl 2-methyl-4-(1-methylethyl)-7-oxo-8-oxa-3-thia-2,4-diazadecanoate",CCOC(CCN(C(C)C)SN(C)C(OC1=CC=CC2=C1OC(C)(C)C2)=O)=O,rat,50,fc; food concentration,104 weeks,25,1.5,0,0
+5369,446,Benomyl,Sherman,1977,JMPR,1995,benzimidazole,fungicide,17804-35-2,methyl [1-[(butylamino)carbonyl]-1H-benzimidazol-2-yl]carbamate,O=C(NCCCC)N1C(NC(OC)=O)=NC2=C1C=CC=C2,rat,36,fc; food concentration,104 weeks,2500,109,0,0
+903,1042,Bensulfuron,Stadler,1986,DAR,2006,"urea, sulfonyl",Herbicide,99283-01-9,"2-[[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]methyl]benzoic acid",COC1=CC(OC)=NC(NC(NS(CC2=CC=CC=C2C(O)=O)(=O)=O)=O)=N1,rat,80,fc; food concentration,104 weeks,750,30,7500,309
+5678,457,Bentazon,Takehara,1984,JMPR,1991,others,herbicide,25057-89-0,"3-(1-methylethyl)-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide",CC(C)N2C(C1=CC=CC=C1NS(=O)2=O)=O,rat,50,fc; food concentration,104 weeks,200,9,800,36
+904,324,Benthiavalicarb-isopropyl,Murata,2001,DAR,2005,carbamate,fungicide,177406-68-7,Isopropyl[(1S)-1-[[[(1R)-1-(6-fluoro-2-benzothiazolyl)ethyl]amino]carbonyl]-2-methylpropyl]carbamic acid,FC1=CC=C2C(SC(C(C)NC(C(C(C)C)NC(OC(C)C)=O)=O)=N2)=C1,rat,80,fc; food concentration,104 weeks,200,9.899999619,5000,249.6000061
+6779,2851,Benzovindiflupyr,Mackay,2012,JMPR,2013,pyrazole,Fungicide,1072957-71-1,"N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide",,rat,64,fc; food concentration,104 weeks,100,4.900000095,600,30.20000076
+2406,988,Bifenazat,Ivett,1999,DAR,2003,others,Acaricide,149877-41-8,"1-methylethyl 2-(4-methoxy[1,1′-biphenyl]-3-yl)hydrazinecarboxylate",COC(C(NNC(OC(C)C)=O)=C2)=CC=C2C1=CC=CC=C1,rat,60,fc; food concentration,104 weeks,20,1,80,3.900000095
+906,90,Bifenox,Ruckman,1987,DAR,2006,diphenyl ether,herbicide,42576-02-3,"methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate",COC(C1=C([N+]([O-])=O)C=CC(OC2=C(Cl)C=C(Cl)C=C2)=C1)=O,rat,50,fc; food concentration,104 weeks,1580,59,5000,187
+908,93,Bifenthrin,McCarthy,1986,DAR,2006,pyrethroid,insecticide,82657-04-3,"[1alpha,3alpha(Z)]-(+/-)-(2-methyl[1,1'-biphenyl]-3-yl)methyl 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate",CC1=C(C3=CC=CC=C3)C=CC=C1COC(C2C(C(C)2C)/C=C(C(F)(F)F)\Cl)=O,rat,50,fc; food concentration,104 weeks,100,4.699999809,200,0
+5671,1030,Bioresmethrin,Vallet,1990,JMPR,1991,pyrethroid,Insecticide,28434-01-7,"[5-(phenylmethyl)-3-furanyl]methyl (1R,3R)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate",CC1(C)C(C(OCC2=COC(CC3=CC=CC=C3)=C2)=O)C1/C=C(C)\C,rat,50,fc; food concentration,104 weeks,50,3,250,15
+4410,2157,Bispyribac,Inoue,1995,DAR,2005,,,125401-92-5,,,rat,58,fc; food concentration,104 weeks,20,1.100000024,200,13.80000019
+2421,72,Bitertanol,Bomhard,1981,DAR,2006,triazole,fungicide,55179-31-2,"beta-([1,1'-biphenyl]-4-yloxy)-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol",CC(C)(C(C(N3C=NC=N3)OC1=CC=C(C2=CC=CC=C2)C=C1)O)C,rat,50,fc; food concentration,104 weeks,100,4.900000095,500,25
+3910,2050,Bixafen,Elligott,2008,DAR,2011,pyrazole,Fungicide,581809-46-3,"N-(3′,4′-dichloro-5-fluoro[1,1′-biphenyl]-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide",ClC1=CC=C(C2=CC(F)=CC=C2NC(C3=CN(C)N=C3C(F)F)=O)C=C1Cl,rat,70,fc; food concentration,104 weeks,50,2.799999952,300,17.39999962
+3911,2050,Bixafen,Elligott,2008,DAR,2011,pyrazole,Fungicide,581809-46-3,"N-(3′,4′-dichloro-5-fluoro[1,1′-biphenyl]-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide",ClC1=CC=C(C2=CC(F)=CC=C2NC(C3=CN(C)N=C3C(F)F)=O)C=C1Cl,rat,70,fc; food concentration,104 weeks,50,2,300,12.10000038
+6611,322,Boscalid,Mellert,2001,DAR,2002,anilide,fungicide,188425-85-6,"2-chloro-N-(4′-chloro[1,1′-biphenyl]-2-yl)-3-pyridinecarboxamide",ClC(N=CC=C3)=C3C(NC1=CC=CC=C1C2=CC=C(Cl)C=C2)=O,rat,20,fc; food concentration,78 weeks,100,4.400000095,500,13
+6629,322,Boscalid,Mellert,2001,DAR,2002,anilide,fungicide,188425-85-6,"2-chloro-N-(4′-chloro[1,1′-biphenyl]-2-yl)-3-pyridinecarboxamide",ClC(N=CC=C3)=C3C(NC1=CC=CC=C1C2=CC=C(Cl)C=C2)=O,rat,50,fc; food concentration,104 weeks,100,4.599999905,500,0
+6634,322,Boscalid,Mellert,2001,DAR,2002,anilide,fungicide,188425-85-6,"2-chloro-N-(4′-chloro[1,1′-biphenyl]-2-yl)-3-pyridinecarboxamide",ClC(N=CC=C3)=C3C(NC1=CC=CC=C1C2=CC=C(Cl)C=C2)=O,rat,20,fc; food concentration,104 weeks,100,4.400000095,500,0
+4954,2181,Bromacil,,,USA,1996,uracil,Herbicide,314-40-9,"5-bromo-6-methyl-3-(1-methylpropyl)-2,4(1H,3H)-pyrimidinedione",,rat,,fc; food concentration,104 weeks,250,9.819999695,2500,103
+911,189,Bromopropylat,Basler,1989,JMPR,1993,benzilate,acaricide,18181-80-1,1-methylethyl 4-bromo-alpha-(4-bromophenyl)-alpha-hydroxybenzeneacetate,CC(OC(C(C1=CC=C(Br)C=C1)(C2=CC=C(Br)C=C2)O)=O)C,rat,80,fc; food concentration,104 weeks,100,3.700000048,700,25.89999962
+5545,189,Bromopropylat,Coulston,1970,JMPR,1993,benzilate,acaricide,18181-80-1,1-methylethyl 4-bromo-alpha-(4-bromophenyl)-alpha-hydroxybenzeneacetate,CC(OC(C(C1=CC=C(Br)C=C1)(C2=CC=C(Br)C=C2)O)=O)C,rat,50,fc; food concentration,104 weeks,0,0,0,0
+2432,190,Bromoxynil,Hamada,1986,DAR,,hydroxybenzonitrile,herbicide,1689-84-5,"3,5-dibromo-4-hydroxybenzonitrile",BrC1=CC(C#N)=CC(Br)=C1O,rat,70,fc; food concentration,104 weeks,60,2.599999905,190,8
+912,998,Bromuconazol,Broadmeadow,1992,DAR,2006,azole,Fungicide,116255-48-2,"1-[[4-bromo-2-(2,4-dichlorophenyl)tetrahydro-2-furanyl]methyl]-1H-1,2,4-triazole",BrC(C3)COC(CN2C=NC=N2)3C1=C(Cl)C=C(Cl)C=C1,rat,40,fc; food concentration,104 weeks,20,0.8799999952,150,6.480000019
+913,192,Bupirimate,Ben-Dyke,1976,DAR,2007,pyrimidine,fungicide,41483-43-6,5-butyl-2-(ethylamino)-6-methyl-4-pyrimidinyl dimethylsulfamate,CCCCC1=C(OS(=O)(N(C)C)=O)N=C(NCC)N=C1C,rat,40,fc; food concentration,104 weeks,1000,25,5000,156
+914,193,Buprofezin,Watanabe,1982,DAR,2006,others,insecticide,953030-84-7,"2-[(1,1-dimethylethyl)imino]tetrahydro-3-(1-methylethyl)-5-phenyl-4H-1,3,5-thiadiazin-4-one",O=C(N1C(C)C)N(C2=CC=CC=C2)CS/C1=N\C(C)(C)C,rat,40,fc; food concentration,104 weeks,20,0.8999999762,200,9
+915,194,Butralin,Fogleman,1974,DAR,2006,"2,6-dinitroaniline",herbicide,33629-47-9,"4-(1,1-dimethylethyl)-N-(1-methylpropyl)-2,6-dinitrobenzenamine",CCC(NC1=C([N+]([O-])=O)C=C(C(C)(C)C)C=C1[N+]([O-])=O)C,rat,35,fc; food concentration,104 weeks,500,20.29999924,1000,40.59999847
+916,78,Cadusafos,Weiner,1986,DAR,2004,organophosphorus,insecticide,95465-99-9,"O-ethyl S,S-bis(1-methylpropyl) phosphorodithioate",O=P(OCC)(SC(C)CC)SC(C)CC,rat,60,fc; food concentration,104 weeks,1,0.04500000179,5,0.2220000029
+917,196,Captan,Benson,1982,DAR,2005,N-trihalomethylthio,fungicide,133-06-2,"3a,4,7,7a-tetrahydro-2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",ClC(Cl)(Cl)SN(C1=O)C(C2C1CC=CC2)=O,rat,50,fd; food dose,104 weeks,0,25,0,100
+2711,196,Captan,Til,1983,DAR,2005,N-trihalomethylthio,fungicide,133-06-2,"3a,4,7,7a-tetrahydro-2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",ClC(Cl)(Cl)SN(C1=O)C(C2C1CC=CC2)=O,rat,50,fc; food concentration,130 weeks,500,24,2000,98
+918,197,Carbaryl,Hamada,1993,DAR,2005,carbamate,insecticide,63-25-2,1-naphthalenyl methylcarbamate,O=C(NC)OC1=C(C=CC=C2)C2=CC=C1,rat,80,fc; food concentration,104 weeks,250,10,1500,60.20000076
+5859,110,Carbendazim,Til,1976,DAR,2009,benzimidazole,fungicide,10605-21-7,methyl 1H-benzimidazol-2-ylcarbamate,O=C(OC)NC2=NC1=CC=CC=C1N2,rat,60,fc; food concentration,104 weeks,10000,599.7999878,0,0
+5860,110,Carbendazim,Sherman,1972,DAR,2009,benzimidazole,fungicide,10605-21-7,methyl 1H-benzimidazol-2-ylcarbamate,O=C(OC)NC2=NC1=CC=CC=C1N2,rat,36,fc; food concentration,104 weeks,500,22,5000,250
+920,113,Carbetamid,Amyes,1988,DAR,2006,carbamate,herbicide,16118-49-3,(R)-N-ethyl-2-[[(phenylamino)carbonyl]oxy]propanamide,O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C,rat,60,fc; food concentration,104 weeks,160,7,1200,55
+921,118,Carbofuran,Spicer,1991,DAR,2004,carbamate,insecticide,1563-66-2,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate",O=C(NC)OC1=C(OC(C)(C)C2)C2=CC=C1,rat,60,fc; food concentration,104 weeks,10,0.4620000124,20,1.169999957
+2483,118,Carbofuran,Goldenthal,1979,DAR,2004,carbamate,insecticide,1563-66-2,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate",O=C(NC)OC1=C(OC(C)(C)C2)C2=CC=C1,rat,90,fc; food concentration,104 weeks,20,1,100,5
+2491,127,Carbosulfan,Norvell,1982,DAR,2004,carbamate,insecticide,55285-14-8,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl [(dibutylamino)thio]methylcarbamate",CCCCN(SN(C(OC2=C1OC(C)(C)CC1=CC=C2)=O)C)CCCC,rat,90,fc; food concentration,104 weeks,20,1,500,25
+923,129,Carboxin,Kehoe,1991,DAR,2006,carboxamide,fungicide,5234-68-4,"5,6-dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide",O=C(C(SCCO2)=C2C)NC1=CC=CC=C1,rat,60,fc; food concentration,104 weeks,20,0.8199999928,200,8.199999809
+924,297,Carfentrazone-ethyl,Hill,1995,USA,1998,others,herbicide,128639-02-1,"Ethyl 2-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorobenzenepropanoate",O=C(OCC)C(Cl)CC1=CC(N2N=C(C)N(C(F)F)C2=O)=C(F)C=C1Cl,rat,70,fc; food concentration,104 weeks,50,3,200,12
+4530,1028,Chlorantraniliprol,,,USA,2008,pyrazole,Insecticide,500008-45-7,3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide,BrC1=NN(C2=NC=CC=C2Cl)C(C(NC3=C(C(NC)=O)C=C(Cl)C=C3C)=O)=C1,rat,,fc; food concentration,104 weeks,0,805,0,0
+5757,135,Chlordan,Ihui,1983,JMPR,1986,cyclodiene organochlorine,insecticide,57-74-9,"1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene",ClC2(C(Cl)3Cl)C(Cl)=C(Cl)C3(Cl)C1C(Cl)C(Cl)CC12,rat,80,fc; food concentration,130 weeks,1,0,5,0
+925,176,Chlorfenapyr,Trutter,1994,JMPR,2012,pyrazole,insecticide,122453-73-0,4-bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile,ClC(C=C2)=CC=C2C1=C(C#N)C(Br)=C(C(F)(F)F)N1COCC,rat,65,fc; food concentration,104 weeks,60,2.900000095,300,15
+926,63,Chlorfenvinphos,Pickering,1980,JMPR,1994,organophosphorus,insecticide,470-90-6,"2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl phosphate",O=P(OCC)(OCC)O/C(C1=CC=C(Cl)C=C1Cl)=C/Cl,rat,50,fc; food concentration,104 weeks,3,0.150000006,30,1.5
+927,154,Chloridazon,Hunter,1977,DAR,2005,pyridazinone,herbicide,1698-60-8,5-amino-4-chloro-2-phenyl-3(2H)-pyridazinone,O=C1C(Cl)=C(N)C=NN1C2=CC=CC=C2,rat,40,fc; food concentration,104 weeks,450,20,1350,60
+2518,154,Chloridazon,Mellert,1993,DAR,2005,pyridazinone,herbicide,1698-60-8,5-amino-4-chloro-2-phenyl-3(2H)-pyridazinone,O=C1C(Cl)=C(N)C=NN1C2=CC=CC=C2,rat,50,fc; food concentration,104 weeks,300,13,1000,50
+928,160,Chlormequat,Schilling,1992,DAR,2007,quaternary ammonium,plant growth regulator,999-81-5,"2-chloro-N,N,N-trimethylethanaminium",C[N+](C)(C)CCCl.[Cl-],rat,20,fc; food concentration,78 weeks,937,43,2811,136
+2532,160,Chlormequat,Mellert,1992,DAR,2007,quaternary ammonium,plant growth regulator,999-81-5,"2-chloro-N,N,N-trimethylethanaminium",C[N+](C)(C)CCCl.[Cl-],rat,50,fc; food concentration,104 weeks,937,42,2811,125
+2732,160,Chlormequat,,1979,DAR,2007,quaternary ammonium,plant growth regulator,999-81-5,"2-chloro-N,N,N-trimethylethanaminium",C[N+](C)(C)CCCl.[Cl-],rat,50,fc; food concentration,104 weeks,0,0,1500,75
+2740,1038,Chloropicrin,Slauter,1995,DAR,2006,others,Fungicide,76-06-2,trichloronitromethane,O=[N+]([O-])C(Cl)(Cl)Cl,rat,30,gc; gavage concentration,104 weeks,0,0.1000000015,0,1
+5653,166,Chlorothalonil,Wilson,1989,JMPR,1990,benzonitrile,fungicide,1897-45-6,"2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile",N#CC1=C(Cl)C(Cl)=C(Cl)C(C#N)=C1Cl,rat,55,fd; food dose,99 weeks,0,1.5,0,3.299999952
+5733,166,Chlorothalonil,Wilson,1985,JMPR,1987,benzonitrile,fungicide,1897-45-6,"2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile",N#CC1=C(Cl)C(Cl)=C(Cl)C(C#N)=C1Cl,rat,60,fc; food concentration,117 weeks,0,0,800,40
+6063,167,Chlorotoluron,Basler,1985,DAR,1999,urea,herbicide,239-592-2,"N'-(3-chloro-4-methylphenyl)-N,N-dimethylurea",CN(C(NC1=CC(Cl)=C(C)C=C1)=O)C,rat,80,fc; food concentration,113 weeks,100,3.700000048,500,0
+930,169,Chlorpropham,Krohmer,1992,JMPR,2000,carbamate,herbicide,101-21-3,1-methylethyl (3-chlorophenyl)carbamate,ClC1=CC=CC(NC(OC(C)C)=O)=C1,rat,60,fd; food dose,104 weeks,0,0,0,30
+931,174,Chlorpyrifos,JMPR,1972,JMPR,1999,organophosphorus,insecticide,2921-88-2,"O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothioate",S=P(OC1=NC(Cl)=C(Cl)C=C1Cl)(OCC)OCC,rat,25,fc; food concentration,104 weeks,0,1,0,10
+5180,174,Chlorpyrifos,Crown,1988,JMPR,1999,organophosphorus,insecticide,2921-88-2,"O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothioate",S=P(OC1=NC(Cl)=C(Cl)C=C1Cl)(OCC)OCC,rat,60,fc; food concentration,104 weeks,5,0.3000000119,100,6
+5185,174,Chlorpyrifos,Young,1988,JMPR,1999,organophosphorus,insecticide,2921-88-2,"O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothioate",S=P(OC1=NC(Cl)=C(Cl)C=C1Cl)(OCC)OCC,rat,60,fd; food dose,104 weeks,0,0.1000000015,0,1
+5652,173,Chlorpyrifos-methyl,Barna-Lloyd,1991,JMPR,1991,organophosphorus,insecticide,5598-13-0,"O,O-dimethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate",ClC1=CC(Cl)=C(OP(OC)(OC)=S)N=C1Cl,rat,60,fc; food concentration,104 weeks,2,0.1000000015,20,1
+932,2034,Chlorsulfuron,Wood,1981,DAR,2007,"urea, triazinylsulfonyl",Herbicide,64902-72-3,"2-chloro-N-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]benzenesulfonamide",O=C(NS(C2=CC=CC=C2Cl)(=O)=O)NC1=NC(C)=NC(OC)=N1,rat,80,fc; food concentration,104 weeks,100,4,500,20
+3922,175,Chlorthal-dimethyl,Lucas,1993,DAR,2006,benzoic acid,herbicide,1861-32-1,"2,3,5,6-tetrachloro-1,4-benzenedicarboxylic acid",O=C(C(C(Cl)=C(Cl)C(C(OC)=O)=C1Cl)=C1Cl)OC,rat,70,fd; food dose,104 weeks,0,1,0,10
+6359,2137,Chromafenozide,Kuwahara,1998,DAR,2011,diacylhydrazine,,143807-66-3,"3,4-dihydro-5-methyl-2H-1-benzopyran-6-carboxylic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide",,rat,50,fc; food concentration,104 weeks,1000,35.79999924,4000,145.1000061
+2746,200,Clethodim,Dougherty,1988,DAR,2006,cyclohexanedione oxime,herbicide,99129-21-2,"(E,E)-(+-)-2-[1-[[(3-chloro-2-propenyl)oxy]imino]propyl]-5-[2-(ethylthio)propyl]-3-hydroxy-2-cyclohexen-1-one",O=C1C(/C(CC)=N\OC/C=C/Cl)=C(O)CC(CC(C)SCC)C1,rat,65,fc; food concentration,104 weeks,500,16,2500,86
+934,451,Clodinafop-propargyl,Fankhauser,1992,DAR,2004,2-(4aryloxyphenoxy)propionic acid,herbicide,105512-06-9,propynyl (R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxypropanoate,CC(C(OCC#C)=O)OC1=CC=C(OC2=C(F)C=C(Cl)C=N2)C=C1,rat,80,fc; food concentration,104 weeks,10,0.3199999928,300,10.19999981
+935,2036,Clofencet,,,USA,1997,others,Plant growth regulator,129025-54-3,"2-(4-chlorophenyl)-3-ethyl-2,5-dihydro-5-oxo-4-pyridazinecarboxylic acid",ClC(C=C2)=CC=C2N1C(CC)=C(C(O)=O)C(C=N1)=O,rat,,fc; food concentration,104 weeks,1000,47,10000,470
+937,201,Clofentezin,Ginocchio,1985,DAR,2005,tetrazine,acaricide,74115-24-5,"3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine",ClC1=C(C2=NN=C(C3=C(Cl)C=CC=C3)N=N2)C=CC=C1,rat,70,fc; food concentration,104 weeks,40,1.720000029,400,17.29999924
+938,202,Clomazone,Morrow,1984,DAR,2005,others,herbicide,81777-89-1,"2-[(2-chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone",ClC1=CC=CC=C1CN2C(C(C)(C)CO2)=O,rat,120,fc; food concentration,104 weeks,1000,50,2000,100
+939,80,Clopyralid,Barna-Lloyd,1985,DAR,2005,pyridine,herbicide,1702-17-6,"3,6-dichloro-2-pyridinecarboxylic acid",ClC1=CC=C(Cl)C(C(O)=O)=N1,rat,70,fd; food dose,104 weeks,0,15,0,150
+2792,80,Clopyralid,Humiston,1977,DAR,2005,pyridine,herbicide,1702-17-6,"3,6-dichloro-2-pyridinecarboxylic acid",ClC1=CC=C(Cl)C(C(O)=O)=N1,rat,40,fc; food concentration,104 weeks,0,0,0,150
+4548,2161,Cloransulam-methyl,,,USA,1997,triazolopyrimidine sulfonanilide,Herbicide,147150-35-4,"3-chloro-2-[[(5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)sulfonyl]amino]benzoic acid",,rat,,fc; food concentration,104 weeks,0,75,0,325
+5978,302,Clothianidin,Biegel,2000,JMPR,2010,guanidine,insecticide,210880-92-5,[C(E)]-N-[(2-chloro-5-thiazolyl)methyl]-N'-methyl-N''-nitroguanidine,CN/C(NCC1=CN=C(Cl)S1)=N\[N+]([O-])=O,rat,80,fc; food concentration,104 weeks,150,9.699999809,500,32.5
+5654,2066,Coumaphos,Eiben,1988,JMPR,1990,organophosphorus,Insecticide,56-72-4,"O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl phosphorothioate",S=P(OCC)(OCC)OC(C=C2)=CC1=C2C(C)=C(Cl)C(O1)=O,rat,50,fc; food concentration,104 weeks,5,0.25,25,1.220000029
+941,203,Cyanamid,Osheroff,1991,DAR,2006,others,herbicide,420-04-2,cyanamide,NC#N,rat,80,gc; gavage concentration,93 weeks,0,1,0,2.5
+6246,2014,Cyantraniliprol,Craig,2011,JMPR,2013,pyrazole,Insecticide,736994-63-1,3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide,BrC1=NN(C3=C(Cl)C=CC=N3)C(C(NC2=C(C)C=C(C#N)C=C2C(NC)=O)=O)=C1,rat,70,fc; food concentration,104 weeks,200,8.300000191,2000,84.80000305
+942,319,Cyazofamid,Nakashima,1999,USA,2004,imidazole,fungicide,120116-88-3,"4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide",CC1=CC=C(C2=C(Cl)N=C(C#N)N2S(N(C)C)(=O)=O)C=C1,rat,50,fc; food concentration,104 weeks,5000,171,0,0
+943,344,Cyclanilid,,,USA,1997,anilide,plant growth regulator,113136-77-9,"1-[[(2,4-dichlorophenyl)amino]carbonyl]cyclopropanecarboxylic acid",OC(C2(CC2)C(NC1=C(Cl)C=C(Cl)C=C1)=O)=O,rat,,fc; food concentration,104 weeks,0,8.100000381,0,25.5
+2824,206,Cycloxydim,Kuehborth,1988,DAR,2006,cyclohexanedione oxime,herbicide,101205-02-1,2-[1-(ethoxyimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexene-1-one,O=C1C(/C(CCC)=N\OCC)=C(O)CC(C2CSCCC2)C1,rat,20,wc; water concentration,78 weeks,100,7,400,28
+2825,206,Cycloxydim,Kuehborth,1988,DAR,2006,cyclohexanedione oxime,herbicide,101205-02-1,2-[1-(ethoxyimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexene-1-one,O=C1C(/C(CCC)=N\OCC)=C(O)CC(C2CSCCC2)C1,rat,50,wc; water concentration,104 weeks,0,0,100,6.400000095
+945,935,Cyflufenamid,Cooper,2001,DAR,2006,amide,Fungicide,180409-60-3,"(Z)-N-[[(cyclopropylmethoxy)amino][2,3-difluoro-6-(trifluoromethyl)phenyl]methylene]benzeneacetamide",O=C(CC3=CC=CC=C3)N/C(C2=C(F)C(F)=CC=C2C(F)(F)F)=N\OCC1CC1,rat,80,fc; food concentration,104 weeks,100,4.400000095,500,22
+6164,1002,Cyflumetofen,Yoshida,2004,DAR,2011,others,Acaricide,400882-07-7,"2-methoxyethyl α-cyano-α-[4-(1,1-dimethylethyl)phenyl]-β-oxo-2-(trifluoromethyl)benzenepropanoate",O=C(C(C2=CC=C(C(C)(C)C)C=C2)(C#N)C(OCCOC)=O)C1=CC=CC=C1C(F)(F)F,rat,30,fc; food concentration,52 weeks,500,18.79999924,1500,0
+6165,1002,Cyflumetofen,Yoshida,2004,DAR,2011,others,Acaricide,400882-07-7,"2-methoxyethyl α-cyano-α-[4-(1,1-dimethylethyl)phenyl]-β-oxo-2-(trifluoromethyl)benzenepropanoate",O=C(C(C2=CC=C(C(C)(C)C)C=C2)(C#N)C(OCCOC)=O)C1=CC=CC=C1C(F)(F)F,rat,50,fc; food concentration,104 weeks,500,16.5,1500,0
+4853,208,Cyfluthrin,Suberg,1983,JMPR,2006,pyrethroid,insecticide,68359-37-5,"cyano(4-fluoro-3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(OC(C#N)C2=CC(OC3=CC=CC=C3)=C(F)C=C2)C1C(/C=C(Cl)/Cl)C(C)1C,rat,65,fc; food concentration,104 weeks,150,6.199999809,450,19.20000076
+4854,208,Cyfluthrin,Wahle,1997,JMPR,2006,pyrethroid,insecticide,68359-37-5,"cyano(4-fluoro-3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(OC(C#N)C2=CC(OC3=CC=CC=C3)=C(F)C=C2)C1C(/C=C(Cl)/Cl)C(C)1C,rat,60,fc; food concentration,104 weeks,225,11.60000038,450,22.79999924
+947,179,Cyhalofop-butyl,,,USA,2002,2-(4aryloxyphenoxy)propionic acid,herbicide,122008-85-9,(2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoic acid + estername,N#CC1=CC(F)=C(OC2=CC=C(OC(C)C(OCCCC)=O)C=C2)C=C1,rat,,fc; food concentration,104 weeks,0,0.8230000138,0,3.440000057
+948,209,"Cyhalothrin, lambda-",Pigott,1984,JMPR,2007,pyrethroid,insecticide,91465-08-6,"[1alpha(S*),3alpha(Z)]-(+/-)-cyano-(3-phenoxyphenyl)methyl 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate",CC(C(C1C(OC(C2=CC=CC(OC3=CC=CC=C3)=C2)C#N)=O)/C=C(C(F)(F)F)\Cl)1C,rat,62,fc; food concentration,104 weeks,50,2.299999952,250,12
+949,210,Cyhexatin,Mertens,2004,JMPR,2005,organotin,acaricide,13121-70-5,tricyclohexylhydroxystannane,O[Sn](C2CCCCC2)(C3CCCCC3)C1CCCCC1,rat,70,fc; food concentration,104 weeks,7.5,0.3400000036,30,1.389999986
+4931,210,Cyhexatin,Eisenlord,1970,JMPR,2005,organotin,acaricide,13121-70-5,tricyclohexylhydroxystannane,O[Sn](C2CCCCC2)(C3CCCCC3)C1CCCCC1,rat,45,fd; food dose,104 weeks,0,3,0,6
+4932,210,Cyhexatin,Warner,1977,JMPR,2005,organotin,acaricide,13121-70-5,tricyclohexylhydroxystannane,O[Sn](C2CCCCC2)(C3CCCCC3)C1CCCCC1,rat,50,fd; food dose,104 weeks,0,0,0,1
+951,211,Cymoxanil,Malleshappa,2003,DAR,2007,urea,fungicide,57966-95-7,2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide,O=C(NC(NCC)=O)/C(C#N)=N\OC,rat,50,fc; food concentration,104 weeks,100,4.699999809,500,23.5
+2889,211,Cymoxanil,Cox,1994,DAR,2007,urea,fungicide,57966-95-7,2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide,O=C(NC(NCC)=O)/C(C#N)=N\OC,rat,72,fc; food concentration,104 weeks,100,4.079999924,700,30.29999924
+952,1615,Cypermethrin,,,JMPR,2006,pyrethroid,Insecticide,52315-07-8,,,rat,,fc; food concentration,104 weeks,0,7.5,0,50
+2664,1616,"Cypermethrin, zeta-",Forbes,1982,DAR,2006,pyrethroid,Insecticide,52315-07-8,"(S)-cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",,rat,52,fc; food concentration,104 weeks,150,7.5,1500,75
+953,214,Cyproconazol,Warren,1988,DAR,2006,triazole,fungicide,94361-06-5,"alpha-(4-chlorophenyl)-alpha-(1-cyclopropylethyl)-1H-1,2,4-triazol-1-ethanol",CC(C(CN2C=NC=N2)(C3=CC=C(C=C3)Cl)O)C1CC1,rat,70,fc; food concentration,104 weeks,50,2.220000029,350,15.53999996
+2954,122,Cyprodinil,Fankhauser,1994,DAR,2005,"pyrimidine, anilino",fungicide,121552-61-2,4-cyclopropyl-6-methyl-N-phenyl-2-pyrimidinamine,CC1=CC(C3CC3)=NC(NC2=CC=CC=C2)=N1,rat,80,fc; food concentration,104 weeks,75,2.700000048,1000,35.59999847
+6717,1613,Cyprosulfamid,Langrand-Lerche,2006,DAR,2012,sulfonamide,Herbicide safener,221667-31-8,N-[[4-[(cyclopropylamino)carbonyl]phenyl]sulfonyl]-2-methoxybenzamide,O=C(NC3CC3)C(C=C2)=CC=C2S(NC(C1=CC=CC=C1OC)=O)(=O)=O,rat,70,fc; food concentration,104 weeks,1000,39,4000,0
+2971,215,Cyromazin,Blair,1982,DAR,2007,"1,3,5-triazine",insecticide,66215-27-8,"N-cyclopropyl-1,3,5-triazine-2,4,6-triamine",NC1=NC(N)=NC(NC2CC2)=N1,rat,70,fc; food concentration,104 weeks,300,14.69999981,3000,156
+5710,221,Daminozid,Johnson,1988,JMPR,1989,others,plant growth regulator,1596-84-5,"butanedioic acid mono(2,2-dimethylhydrazide",CN(NC(CCC(O)=O)=O)C,rat,60,fc; food concentration,105 weeks,5000,243,10000,486
+957,961,Dazomet,Kühborth,1989,DAR,2007,dithiocarbamate,Fungicide,533-74-4,"tetrahydro-3,5-dimethyl-2H-1,3,5-thiadiazine-2-thione",CN(CN1C)CSC1=S,rat,20,fc; food concentration,104 weeks,20,0.8999999762,80,3.599999905
+2984,961,Dazomet,Kühborth,1989,DAR,2007,dithiocarbamate,Fungicide,533-74-4,"tetrahydro-3,5-dimethyl-2H-1,3,5-thiadiazine-2-thione",CN(CN1C)CSC1=S,rat,50,fc; food concentration,104 weeks,20,0.8999999762,80,5.300000191
+958,222,Deltamethrin,Goldenthal,1980,JMPR,2000,pyrethroid,insecticide,52918-63-5,"[1R-[1alpha(S*), 3 alpha]]-cyano (3-phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-dimethylcycropropanecarboxylate",CC1(C)C(/C=C(Br)/Br)C1C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O,rat,90,fc; food concentration,104 weeks,20,1,50,2.5
+5170,222,Deltamethrin,Ryle,1995,JMPR,2000,pyrethroid,insecticide,52918-63-5,"[1R-[1alpha(S*), 3 alpha]]-cyano (3-phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-dimethylcycropropanecarboxylate",CC1(C)C(/C=C(Br)/Br)C1C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O,rat,70,fc; food concentration,104 weeks,25,1.100000024,125,5.400000095
+5694,225,Demeton-S-methyl,Schmidt,1988,JMPR,1989,organophosphorus,insecticide,919-86-8,"S-[2-(ethylthio)ethyl] O,O-dimethyl phosphorothioate",O=P(OC)(OC)SCCSCC,rat,60,fc; food concentration,104 weeks,1,0.05000000075,7,0.349999994
+5706,223,Demeton-S-methyl-sulfon,Suberg,1988,JMPR,1989,organophosphorus,insecticide,17040-19-6,S-[2-(ethylsulfonyl)ethyl],CCS(CCSP(OC)(OC)=O)(=O)=O,rat,60,wc; water concentration,104 weeks,1,0.05999999866,5,0.3000000119
+959,226,Desmedipham,,,UK,1993,"carbamate, bis-",herbicide,13684-56-5,ethyl [3-[[(phenylamino)carbonyl]oxy]phenyl]carbamate,O=C(OCC)NC1=CC=CC(OC(NC2=CC=CC=C2)=O)=C1,rat,,fc; food concentration,104 weeks,0,0,0,3.200000048
+960,231,Diazinon,Kirchner,1991,DAR,2005,organophosphorus,insecticide,333-41-5,"O,O-diethyl O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl]- phosphorothioate",S=P(OCC)(OCC)OC1=NC(C(C)C)=NC(C)=C1,rat,30,fc; food concentration,104 weeks,1.5,0.05999999866,125,5
+3005,231,Diazinon,Angel,,DAR,2005,organophosphorus,insecticide,333-41-5,"O,O-diethyl O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl]- phosphorothioate",S=P(OCC)(OCC)OC1=NC(C(C)C)=NC(C)=C1,rat,50,fc; food concentration,104 weeks,0,0,0,0
+961,232,Dicamba,Goldenthal,1985,DAR,2007,benzoic acid,herbicide,1918-00-9,"3,6-dichloro-2-methoxybenzoic acid",O=C(O)C1=C(OC)C(Cl)=CC=C1Cl,rat,60,fc; food concentration,104 weeks,2500,99,0,0
+3018,233,Dichlobenil,Inoue,1984,DAR,2008,benzonitrile,herbicide,1194-65-6,"2,6-dichlorobenzonitrile",N#CC(C(Cl)=CC=C1)=C1Cl,rat,70,fc; food concentration,104 weeks,0,0,50,3.200000048
+962,235,Dichlorprop-P,Mitsumori,1984,DAR,2004,"alkanoic acid, aryloxy",herbicide,15165-67-0,"(+)-2-(2,4-dichlorophenoxy)propanoic acid",CC(C(O)=O)OC(C=CC(Cl)=C1)=C1Cl,rat,80,fc; food concentration,104 weeks,300,11.01000023,1000,36.5
+3094,236,Dichlorvos,Witherup,1967,DAR,2005,organophosphorus,insecticide,62-73-7,"2,2-dichloroethenyl dimethyl phosphate",O=P(OC)(OC)O/C=C(Cl)\Cl,rat,25,fc; food concentration,104 weeks,4.670000076,0.2300000042,46.70000076,2.299999952
+3096,236,Dichlorvos,NTP,1989,DAR,2005,organophosphorus,insecticide,62-73-7,"2,2-dichloroethenyl dimethyl phosphate",O=P(OC)(OC)O/C=C(Cl)\Cl,rat,50,gc; gavage concentration,104 weeks,0,0,0,0
+4428,237,Diclofop-methyl,Schollmeier,1990,DAR,2009,2-(4aryloxyphenoxy)propionic acid,herbicide,51338-27-3,"Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid",CC(OC1=CC=C(OC2=CC=C(Cl)C=C2Cl)C=C1)C(OC)=O,rat,90,fc; food concentration,104 weeks,2,0.1000000015,6.300000191,0
+4429,237,Diclofop-methyl,Ehling,1996,DAR,2009,2-(4aryloxyphenoxy)propionic acid,herbicide,51338-27-3,"Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid",CC(OC1=CC=C(OC2=CC=C(Cl)C=C2Cl)C=C1)C(OC)=O,rat,80,fc; food concentration,104 weeks,0,0,4.5,0.200000003
+965,238,Dicloran,Lessel,1974,DAR,2006,"aniline, nitro",fungicide,99-30-9,"2,6-dichloro-4-nitrobenzenamine",[O-][N+](C1=CC(Cl)=C(N)C(Cl)=C1)=O,rat,25,no study,104 weeks,0,0,0,0
+3133,238,Dicloran,Woodard,1964,DAR,2006,"aniline, nitro",fungicide,99-30-9,"2,6-dichloro-4-nitrobenzenamine",[O-][N+](C1=CC(Cl)=C(N)C(Cl)=C1)=O,rat,35,fc; food concentration,104 weeks,100,3.369999886,3000,117
+5642,239,Dicofol,Hazelton,1989,JMPR,1992,organochlorine,acaricide,115-32-2,4-chloro-alpha-(4-chlorophenyl)-alpha-(trichloromethyl)benzenemethanol,OC(C1=CC=C(Cl)C=C1)(C2=CC=C(Cl)C=C2)C(Cl)(Cl)Cl,rat,60,fc; food concentration,104 weeks,5,0.2199999988,50,2.200000048
+4419,2158,Didecyldimethylammonium-chlorid,Gill,1991,DAR,2008,,,7173-51-5,,,rat,60,fc; food concentration,104 weeks,750,32,1500,64
+3151,242,Diethofencarb,Cox,1989,DAR,2007,"carbamate, phenyl",fungicide,87130-20-9,"1-methylethyl (3,4-diethoxyphenyl)carbamate",CCOC1=CC=C(C=C1OCC)NC(OC(C)C)=O,rat,80,fc; food concentration,104 weeks,1000,42.70000076,5000,220.3000031
+3164,243,Difenoconazol,Cox,1989,DAR,2006,triazole,fungicide,119446-68-3,"1-[2-[4-(4-chlorophenoxy)-2-chlorophenyl]-4-methyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole",CC2COC(O2)(C4=CC=C(C=C4Cl)OC3=CC=C(Cl)C=C3)CN1C=NC=N1,rat,80,fc; food concentration,104 weeks,20,1,500,24.10000038
+3178,245,Diflubenzuron,Hunter,1976,DAR,2006,"urea, benzoyl",insecticide,35367-38-5,"N-[[(4-chlorophenyl)amino]carbonyl]-2,6-difluorobenzamide",O=C(NC(NC2=CC=C(Cl)C=C2)=O)C1=C(F)C=CC=C1F,rat,60,fc; food concentration,104 weeks,160,5.800000191,0,0
+3179,245,Diflubenzuron,Burdock,1984,DAR,2006,"urea, benzoyl",insecticide,35367-38-5,"N-[[(4-chlorophenyl)amino]carbonyl]-2,6-difluorobenzamide",O=C(NC(NC2=CC=C(Cl)C=C2)=O)C1=C(F)C=CC=C1F,rat,50,fc; food concentration,104 weeks,625,31.20000076,2500,125
+969,246,Diflufenican,Holmes,1987,DAR,2006,anilide,herbicide,83164-33-4,"N-(2,4-difluorophenyl)-2-[3-(trifluormethyl)phenoxy]-3-pyridinecarboxamide",O=C(C2=CC=CN=C2OC3=CC=CC(C(F)(F)F)=C3)NC1=CC=C(F)C=C1F,rat,50,fc; food concentration,104 weeks,500,23.27000046,2500,119.5999985
+970,342,Diflufenzopyr,,,USA,1999,"urea, phenyl",herbicide,109293-97-2,"2-[1-[[[(3,5-difluorophenyl)amino]carbonyl]hydrazono]ethyl]-3-pyridinecarboxylic acid",C/C(C1=NC=CC=C1C(O)=O)=N\NC(NC2=CC(F)=CC(F)=C2)=O,rat,,fc; food concentration,104 weeks,5000,236,10000,472
+971,247,Dimefuron,,,UK,1993,oxadiazolone,herbicide,34205-21-5,"N'-[3-chloro-4-[5-(1,1-dimethylethyl)-2-oxo-1,3,4-oxadiazol-3(2H)-yl]phenyl]-N,N-dimethylurea",O=C(NC1=CC(Cl)=C(N2N=C(C(C)(C)C)OC2=O)C=C1)N(C)C,rat,,fc; food concentration,104 weeks,0,7,0,22
+972,248,Dimethachlor,Fankhauser,1995,DAR,2007,chloroacetanilide,herbicide,50563-36-5,"2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide",COCCN(C1=C(C)C=CC=C1C)C(CCl)=O,rat,70,fc; food concentration,104 weeks,300,11.10000038,4000,157
+3197,249,Dimethenamid,Ruckman,1990,DAR,2005,others,herbicide,87674-68-8,"(RS) 2-chloro-N-(2,4-dimethyl-3-thienyl)-N-(2-methoxy-1-methylethyl)acetamide",O=C(N(C1=C(C)SC=C1C)C(C)COC)CCl,rat,70,fc; food concentration,104 weeks,0,0,100,5
+3207,1039,Dimethipin,Goldenthal,1996,DAR,2005,others,Plant growth regulator,55290-64-7,"2,3-dihydro-5,6-dimethyl-1,4-dithiin 1,1,4,4-tetraoxide",O=S(C(C)=C(C)S(CC1)(=O)=O)1=O,rat,60,fc; food concentration,104 weeks,40,1.799999952,875,50
+975,250,Dimethoat,Hellwig,1986,DAR,2005,organophosphorus,insecticide,60-51-5,"O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] phosphorodithioate",S=P(OC)(OC)SCC(NC)=O,rat,65,fc; food concentration,104 weeks,1,0.03999999911,5,0.200000003
+3276,250,Dimethoat,Lewerenz,1970,DAR,2005,organophosphorus,insecticide,60-51-5,"O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] phosphorodithioate",S=P(OC)(OC)SCC(NC)=O,rat,30,fc; food concentration,104 weeks,0.1000000015,0,1,0
+3330,66,Dimethomorph,Everett,1990,DAR,2005,morpholine,fungicide,110488-70-5,"4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine",O=C(N2CCOCC2)/C=C(C3=CC=C(Cl)C=C3)/C1=CC=C(OC)C(OC)=C1,rat,20,fc; food concentration,104 weeks,200,9,750,36
+3332,66,Dimethomorph,Everett,1991,DAR,2005,morpholine,fungicide,110488-70-5,"4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine",O=C(N2CCOCC2)/C=C(C3=CC=C(Cl)C=C3)/C1=CC=C(OC)C(OC)=C1,rat,50,fc; food concentration,104 weeks,200,9,750,34
+977,990,Dimoxystrobin,Mellert,2001,DAR,2005,strobilurin,Fungicide,149961-52-4,"aE)-2-[(2,5-dimethylphenoxy)methyl]-a-(methoxyimino)-N-methylbenzeneacetamide",CC1=CC=C(C)C=C1OCC2=CC=CC=C2/C(C(NC)=O)=N/OC,rat,20,fc; food concentration,104 weeks,150,7,500,23
+978,252,Dinocap,Maita,1980,JMPR,1998,"benzene, nitro",fungicide,39300-45-3,"(E)-2-(methylheptyl)-4,6-dinitrophenyl 2-butenoate",C/C=C/C(OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1C(C)CCCCCC)=O,rat,80,fc; food concentration,130 weeks,200,6.400000095,2000,64
+979,2037,Dinotefuran,,,USA,2004,guanidine,Insecticide,165252-70-0,N-methyl-N′-nitro-N″-[(tetrahydro-3-furanyl)methyl]guanidine,[O][N](N=C(NC)NCC1COCC1)=O,rat,,fc; food concentration,104 weeks,0,99.69999695,0,991
+980,257,Diphenylamin,Botta,1994,DAR,2007,,fungicide,122-39-4,N-phenylbenzenamine,C1(NC2=CC=CC=C2)=CC=CC=C1,rat,60,fc; food concentration,104 weeks,150,7.5,500,25
+981,258,Diquat,Colley,1985,JMPR,2013,bipyridylium,herbicide,2764-72-9,"6,7-dihydrodipyrido[1,2-a:2´,1´-c]pyrazinediium",[N+]12=CC=CC=C1C3=[N+](C=CC=C3)CC2,rat,60,fc; food concentration,104 weeks,15,0.5799999833,75,2.910000086
+5533,258,Diquat,Rogerson,1978,JMPR,1993,bipyridylium,herbicide,2764-72-9,"6,7-dihydrodipyrido[1,2-a:2´,1´-c]pyrazinediium",[N+]12=CC=CC=C1C3=[N+](C=CC=C3)CC2,rat,35,fc; food concentration,104 weeks,25,1.299999952,75,3.900000095
+3368,260,Dithianon,Brown,1991,DAR,2006,quinone,fungicide,3347-22-6,"5,10-dihydro-5,10-dioxonaphtho[2,3-b]-1,4-dithi-in-2,3-dicarbonitrile",O=C(C2=C1C=CC=C2)C(SC(C#N)=C(C#N)S3)=C3C1=O,rat,70,fc; food concentration,104 weeks,20,1,120,6
+3378,261,Diuron,Schmidt,1985,DAR,2005,"urea, phenyl",herbicide,330-54-1,"N'-(3,4-dichlorophenyl)-N,N-dimethylurea",O=C(N(C)C)NC1=CC(Cl)=C(Cl)C=C1,rat,60,fc; food concentration,104 weeks,0,0,25,1.700000048
+984,83,Dodemorph,Vincenti,2004,DAR,2007,morpholine,fungicide,1593-77-7,"4-cyclododecyl-2,6-dimethylmorpholine",CC(C2)OC(C)CN2C1CCCCCCCCCCC1,rat,70,fc; food concentration,104 weeks,833,45,2500,136
+3420,84,Dodin,Dange,1998,DAR,2009,guanidine,fungicide,2439-10-3,dodecylguanidine monoacetate,N=C(N)NCCCCCCCCCCCC.OC(C)=O,rat,60,fc; food concentration,104 weeks,400,20,800,42
+3467,1619,Emamectin,Gerson,1992,DAR,2008,avermectin,Insecticide,155569-91-8,(4″R)-4″-deoxy-4″-(methylamino)avermectin B1,C/C(C(C(/C=C/C=C4/C5(O)C(C(O)C(C)=CC5C6=O)OC4)C)OC2CC(OC)C(OC7CC(OC)C(NC)C(C)O7)C(C)O2)=C\CC1CC(O6)CC3(OC(C([R])C)C(C)C=C3)O1,rat,20,fd; food dose,52 weeks,0,1,0,2.5
+3472,1619,Emamectin,Lankas,1994,DAR,2008,avermectin,Insecticide,155569-91-8,(4″R)-4″-deoxy-4″-(methylamino)avermectin B1,C/C(C(C(/C=C/C=C4/C5(O)C(C(O)C(C)=CC5C6=O)OC4)C)OC2CC(OC)C(OC7CC(OC)C(NC)C(C)O7)C(C)O2)=C\CC1CC(O6)CC3(OC(C([R])C)C(C)C=C3)O1,rat,75,fc; food concentration,104 weeks,0,0.25,0,1
+5250,85,Endosulfan,US NCI,1978,JMPR,1998,organochlorine,insecticide,115-29-7,"6,7,8,9,10,10,-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide",O=S3OCC1C(CO3)C2(Cl)C(Cl)=C(Cl)C(Cl)1C(Cl)2Cl,rat,50,fc; food concentration,78 weeks,0,0,220,11
+5251,85,Endosulfan,Ruckman,1989,JMPR,1998,organochlorine,insecticide,115-29-7,"6,7,8,9,10,10,-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide",O=S3OCC1C(CO3)C2(Cl)C(Cl)=C(Cl)C(Cl)1C(Cl)2Cl,rat,50,fc; food concentration,104 weeks,15,0.6000000238,75,2.900000095
+5252,85,Endosulfan,Keller,1959,JMPR,1998,organochlorine,insecticide,115-29-7,"6,7,8,9,10,10,-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide",O=S3OCC1C(CO3)C2(Cl)C(Cl)=C(Cl)C(Cl)1C(Cl)2Cl,rat,25,fc; food concentration,104 weeks,30,1.5,100,5
+986,126,Epoxiconazol,Mellert,1992,DAR,2006,triazole,fungicide,133855-98-8,"rel-1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole",FC1=CC=C(C2(CN4C=NC=N4)C(C3=CC=CC=C3Cl)O2)C=C1,rat,20,fc; food concentration,104 weeks,30,1,150,5
+3491,126,Epoxiconazol,Mellert,1992,DAR,2006,triazole,fungicide,133855-98-8,"rel-1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole",FC1=CC=C(C2(CN4C=NC=N4)C(C3=CC=CC=C3Cl)O2)C=C1,rat,50,fc; food concentration,104 weeks,30,2,150,6
+987,267,Esfenvalerat,,,JMPR,2002,pyrethroid,insecticide,66230-04-4,"[S-(R*,R*)]-cyano(3-phenoxyphenyl)methyl 4-chloro-2-(1-methylethyl)benzeneacetate",N#CC(C2=CC(OC3=CC=CC=C3)=CC=C2)OC(C(C(C)C)C1=CC=C(Cl)C=C1)=O,rat,,fc; food concentration,104 weeks,0,7.5,0,25
+5094,267,Esfenvalerat,Gordon,1978,JMPR,2002,pyrethroid,insecticide,66230-04-4,"[S-(R*,R*)]-cyano(3-phenoxyphenyl)methyl 4-chloro-2-(1-methylethyl)benzeneacetate",N#CC(C2=CC(OC3=CC=CC=C3)=CC=C2)OC(C(C(C)C)C1=CC=C(Cl)C=C1)=O,rat,93,fc; food concentration,104 weeks,250,12,500,0
+5095,267,Esfenvalerat,Arai,1980,JMPR,2002,pyrethroid,insecticide,66230-04-4,"[S-(R*,R*)]-cyano(3-phenoxyphenyl)methyl 4-chloro-2-(1-methylethyl)benzeneacetate",N#CC(C2=CC(OC3=CC=CC=C3)=CC=C2)OC(C(C(C)C)C1=CC=C(Cl)C=C1)=O,rat,80,fc; food concentration,104 weeks,150,7.5,500,0
+988,467,Ethaboxam,,,USA,2006,carboxamide,fungicide,162650-77-3,N-(cyano-2-thienylmethyl)-4-ethyl-2-(ethylamino)-5-thiazolecarboxamide,CCC1=C(C(NC(C2=CC=CS2)C#N)=O)SC(NCC)=N1,rat,,fc; food concentration,104 weeks,100,5.5,300,16.39999962
+989,1033,Ethalfluralin,Adams,1981,DAR,2007,dinitroaniline,Herbicide,55283-68-6,"N-ethyl-N-(2-methyl-2-propenyl)-2,6-dinitro-4-(trifluoromethyl)benzenamine",FC(F)(F)C1=CC([N+]([O-])=O)=C(N(CC(C)=C)CC)C([N+]([O-])=O)=C1,rat,30,fc; food concentration,104 weeks,100,4.199999809,250,10.69999981
+3500,1033,Ethalfluralin,Adams,,DAR,2007,dinitroaniline,Herbicide,55283-68-6,"N-ethyl-N-(2-methyl-2-propenyl)-2,6-dinitro-4-(trifluoromethyl)benzenamine",FC(F)(F)C1=CC([N+]([O-])=O)=C(N(CC(C)=C)CC)C([N+]([O-])=O)=C1,rat,15,fc; food concentration,52 weeks,250,9.300000191,750,29
+6466,2424,Ethametsulfuron-methyl,Bogdanffy,1991,DAR,2012,"urea, triazinylsulfonyl",Herbicide,97780-06-8,"methyl 2-[[[[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]amino]carbonyl]amino]sulfonyl]benzoate",,rat,72,fc; food concentration,104 weeks,500,21,5000,210
+3511,268,Ethephon,VanMiller,1989,DAR,2004,others,plant growth regulator,16672-87-0,(2-chloroethyl)phosphonic acid,O=P(O)(O)CCCl,rat,90,fc; food concentration,104 weeks,300,13,3000,131
+5753,270,Ethion,Morrow,1985,JMPR,1986,organophosphorus,insecticide,563-12-2,"S,S′-methylene bis(O,O-diethyl phosphorodithioate)",S=P(OCC)(OCC)SCSP(OCC)(OCC)=S,rat,80,fc; food concentration,104 weeks,4,0.1800000072,40,1.799999952
+6292,2428,Ethiprole,,,USA,2011,"pyrazole, phenyl",Insecticide,181587-01-9,"5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile",,rat,,fc; food concentration,104 weeks,20,0.8500000238,75,3.200000048
+3525,273,Ethoprophos,Spicer,1985,DAR,2004,organophosphorus,insecticide,13194-48-4,"O-ethyl S,S-dipropyl phosphorodithioate",O=P(SCCC)(OCC)SCCC,rat,70,fc; food concentration,104 weeks,1,0.05000000075,10,0.5
+3526,273,Ethoprophos,Williams,1992,DAR,2004,organophosphorus,insecticide,13194-48-4,"O-ethyl S,S-dipropyl phosphorodithioate",O=P(SCCC)(OCC)SCCC,rat,80,fc; food concentration,104 weeks,1,0.03999999911,60,2.440000057
+5239,274,Ethoxyquin,,,JMPR,1998,"quinoline, phenoxy",fungicide,91-53-2,"6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoline",CC2(C)C=C(C)C1=CC(OCC)=CC=C1N2,rat,10,fc; food concentration,104 weeks,125,6,250,12
+3541,87,Etofenprox,Green,1986,DAR,2007,pyrethroid,insecticide,80844-07-1,1-[[2-(4-ethoxyphenyl)-2-methylpropoxy]methyl]-3-phenoxybenzene,CCOC1=CC=C(C(C)(C)COCC2=CC(OC3=CC=CC=C3)=CC=C2)C=C1,rat,50,fc; food concentration,108 weeks,100,3.700000048,700,25.5
+5947,347,Etoxazol,Nakashima,1996,JMPR,2010,others,acaricide,153233-91-1,"2-(2,6-difluorophenyl)-4-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydrooxazole",FC1=CC=CC(F)=C1C(OC3)=NC3C2=CC=C(C(C)(C)C)C=C2OCC,rat,60,fd; food dose,104 weeks,0,64,0,0
+5948,347,Etoxazol,Nakashima,2001,JMPR,2010,others,acaricide,153233-91-1,"2-(2,6-difluorophenyl)-4-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydrooxazole",FC1=CC=CC(F)=C1C(OC3)=NC3C2=CC=C(C(C)(C)C)C=C2OCC,rat,65,fc; food concentration,104 weeks,50,1.830000043,5000,187
+993,1043,Etridiazol,Trutter,1988,DAR,2007,others,Fungicide,2593-15-9,"5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole",ClC(Cl)(Cl)C1=NSC(OCC)=N1,rat,50,fc; food concentration,104 weeks,0,0,100,5
+994,332,Famoxadon,MacKenzie,1996,JMPR,2003,strobilurin,fungicide,131807-57-3,"5-methyl-5-(4-phenoxyl)-3-phenylamino-2,4-oxazolidinedione",O=C(C(O3)(C)C(C=C2)=CC=C2OC1=CC=CC=C1)N(NC4=CC=CC=C4)C3=O,rat,92,fc; food concentration,104 weeks,200,8.399999619,400,17
+6080,305,Fenamidon,Bigot,1999,JMPR,2013,imidazolinone,fungicide,161326-34-7,"(5S)-3,5-dihydro-5-methyl-2-(methylthio)-5-phenyl-3-(phenylamino)-4H-imidazol-4-one",O=C1N(NC3=CC=CC=C3)C(SC)=NC(C)1C2=CC=CC=C2,rat,70,fc; food concentration,104 weeks,60,2.799999952,150,7.099999905
+3557,276,Fenamiphos,Löser,1972,DAR,2005,organophosphorus,Nematicide,22224-92-6,ethyl 3-methyl-4-(methylthio)phenyl (1-methylethyl)phosphoramidate,O=P(OCC)(OC1=CC=C(SC)C(C)=C1)NC(C)C,rat,40,fc; food concentration,104 weeks,10,0.5600000024,30,1.700000048
+3558,276,Fenamiphos,Hayes,1986,DAR,2005,organophosphorus,Nematicide,22224-92-6,ethyl 3-methyl-4-(methylthio)phenyl (1-methylethyl)phosphoramidate,O=P(OCC)(OC1=CC=C(SC)C(C)=C1)NC(C)C,rat,70,fc; food concentration,104 weeks,1.700000048,0.1000000015,7.800000191,0.4600000083
+996,277,Fenarimol,Hoffman,1978,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,20,fc; food concentration,78 weeks,50,2.299999952,130,3.599999905
+5343,277,Fenarimol,Hoffman,1978,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,20,fc; food concentration,52 weeks,130,6.5,350,17.5
+5344,277,Fenarimol,Hoffman,1978,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,40,fc; food concentration,104 weeks,0,0,50,2
+5345,277,Fenarimol,Hoffman,1982,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,25,1.200000048,50,2.5
+5346,277,Fenarimol,Hoffman,1985,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,50,2,0,0
+997,88,Fenazaquin,Cocke,1992,DAR,2006,others,acaricide,120928-09-8,"4-[[4-(1,1-dimethylethyl)phenyl]ethoxy]quinazoline",CC(C)(C1=CC=C(CCOC2=NC=NC3=CC=CC=C23)C=C1)C,rat,60,fc; food concentration,104 weeks,10,0.4600000083,100,4.5
+3571,136,Fenbuconazol,Wolfe,1990,DAR,2006,triazole,fungicide,114369-43-6,"alpha-[2-(4-chlorophenyl)ethyl]-alpha-phenyl-1H-1,2,4-triazole-1-propanenitrile",ClC(C=C2)=CC=C2CCC(C#N)(CN3C=NC=N3)C1=CC=CC=C1,rat,70,fc; food concentration,104 weeks,80,3,800,31
+999,278,Fenbutatin Oxid,Simpson,1973,DAR,2009,organotin,acaricide,13356-08-6,hexakis(2-methyl-2-phenylpropyl)distannoxane,CC(C1=CC=CC=C1)(C)C[Sn](CC(C)(C2=CC=CC=C2)C)(CC(C)(C3=CC=CC=C3)C)O[Sn](CC(C)(C4=CC=CC=C4)C)(CC(C)(C6=CC=CC=C6)C)CC(C)(C5=CC=CC=C5)C,rat,72,fc; food concentration,104 weeks,100,5,300,15
+1000,348,Fenhexamid,Eiben,1996,JMPR,2005,anilide,fungicide,126833-17-8,"Cyclohexanecarboxamide, N-(2,3-dichliro-4-hydroxyphenyl)-1-ethyl-",CC1(C(NC2=CC=C(O)C(Cl)=C2Cl)=O)CCCCC1,rat,50,fc; food concentration,104 weeks,500,28,5000,292
+3583,281,Fenitrothion,Kadota,1974,DAR,2005,organophosphorus,insecticide,122-14-5,"O,O-dimethyl O-(3-methyl-4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC(C)=C([N+]([O-])=O)C=C1,rat,15,fc; food concentration,93 weeks,10,0.5,0,0
+3584,281,Fenitrothion,Kundzins,1974,DAR,2005,organophosphorus,insecticide,122-14-5,"O,O-dimethyl O-(3-methyl-4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC(C)=C([N+]([O-])=O)C=C1,rat,50,fc; food concentration,104 weeks,10,0.5,30,23.10000038
+3603,995,Fenoxaprop,,,DAR,2006,"(4-aryloxyphenoxy)propionic acid, 2-",Herbicide,95617-09-7,2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]propanoic acid,CC(C(O)=O)OC(C=C3)=CC=C3OC2=NC1=CC=C(Cl)C=C1O2,rat,,no study,104 weeks,0,0,0,0
+3605,995,Fenoxaprop,Donaubauer,1985,DAR,2006,"(4-aryloxyphenoxy)propionic acid, 2-",Herbicide,95617-09-7,2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]propanoic acid,CC(C(O)=O)OC(C=C3)=CC=C3OC2=NC1=CC=C(Cl)C=C1O2,rat,116,fc; food concentration,120 weeks,30,1.600000024,180,9.399999619
+1003,283,Fenoxycarb,Goodyer,1992,DAR,2009,carbamate,insecticide,72490-01-8,ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate,O=C(OCC)NCCOC1=CC=C(OC2=CC=CC=C2)C=C1,rat,60,fc; food concentration,104 weeks,200,8.100000381,600,24.70000076
+1004,284,Fenpiclonil,,,UK,1993,"pyrrole, phenyl",fungicide,74738-17-3,"4-(2,3-dichlorophenyl)-1H-pyrrole-3-carbonitrile",ClC1=CC=CC(C2=CNC=C2C#N)=C1Cl,rat,,fc; food concentration,104 weeks,0,30,0,120
+1005,285,Fenpropathrin,Warren,1986,JMPR,2012,pyrethroid,insecticide,39515-41-8,"cyano(3-phenoxyphenyl)methyl 2,2,3,3-tetramethylcyclopropanecarboxylate",CC(C(C(C)3C)C(OC(C1=CC=CC(OC2=CC=CC=C2)=C1)C#N)=O)3C,rat,50,fc; food concentration,104 weeks,150,7,450,21
+1006,89,Fenpropidin,Crome,1989,DAR,2006,others,fungicide,67306-00-7,"(+/-)-1-[3-[4-(1,1-dimethylethyl)phenyl{]-2-methylpropyl]piperidine",CC(CC2=CC=C(C(C)(C)C)C=C2)CN1CCCCC1,rat,80,fc; food concentration,104 weeks,50,2.269999981,250,11.82999992
+1007,286,Fenpropimorph,hunter,1982,DAR,2007,morpholine,fungicide,67564-91-4,"cis-4-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine",CC(CC2=CC=C(C(C)(C)C)C=C2)CN1CC(OC(C1)C)C,rat,75,fc; food concentration,104 weeks,10,0.3000000119,50,1.700000048
+6143,2456,Fenpyrazamine,Sommer,2009,DAR,2011,pyrazole,Fungicide,473798-59-3,"S-2-propen-1-yl 5-amino-2,3-dihydro-2-(1-methylethyl)-4-(2-methylphenyl)-3-oxo-1H-pyrazole-1-carbothioate",,rat,70,fc; food concentration,104 weeks,100,5.289999962,300,0
+1008,287,Fenpyroximate,Aughton,1989,DAR,2006,pyrazole,acaricide,111812-58-9,"(E)-1,1-dimethylethyl 4-[[[[(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino]oxy]methyl]benzoate",O=C(OC(C)(C)C)C1=CC=C(CO/N=C/C2=C(OC3=CC=CC=C3)N(C)N=C2C)C=C1,rat,80,fc; food concentration,104 weeks,25,0.9700000286,75,3
+130,289,Fenthion,Christenson,1990,JMPR,1995,organophosphorus,insecticide,55-38-9,"O,O-dimethyl O-[3-methyl-4-(methylthio)phenyl] phosphorothioate",S=P(OC)(OC)OC1=CC(C)=C(SC)C=C1,rat,50,fc; food concentration,104 weeks,0,0,5,0.200000003
+1009,289,Fenthion,Bomhard,1977,JMPR,1995,organophosphorus,insecticide,55-38-9,"O,O-dimethyl O-[3-methyl-4-(methylthio)phenyl] phosphorothioate",S=P(OC)(OC)OC1=CC(C)=C(SC)C=C1,rat,100,fc; food concentration,104 weeks,3,0.1400000006,15,0.7200000286
+6932,290,Fenvalerat,Arai,1980,JMPR,2012,pyrethroid,insecticide,51630-58-1,cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate,ClC1=CC=C(C(C(C)C)C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O)C=C1,rat,80,fc; food concentration,104 weeks,150,7.5,500,25
+6933,290,Fenvalerat,Gordon,1978,JMPR,2012,pyrethroid,insecticide,51630-58-1,cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate,ClC1=CC=C(C(C(C)C)C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O)C=C1,rat,93,fc; food concentration,78 weeks,250,12.5,500,25
+5330,2013,Ferbam,,,JMPR,1996,dithiocarbamate,Fungicide,14484-64-1,"(OC-6-11)-tris(dimethylcarbamodithioato-κS,κS′)iron",,rat,25,fc; food concentration,104 weeks,250,12.5,2500,125
+3644,137,Fipronil,Aughton,1992,DAR,2005,"pyrazole, phenyl",insecticide,120068-37-3,"5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(1R,S)-(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile",ClC(C=C(C=C1Cl)C(F)(F)F)=C1N2N=C(C(S(C(F)(F)F)=O)=C2N)C#N,rat,65,fc; food concentration,104 weeks,0.5,0.01899999939,1.5,0.05900000036
+4604,91,Flazasulfuron,Kitazawa,1995,USA,2007,"urea, sulfonyl",herbicide,104040-78-0,"N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-3-(trifluoromethyl)-2-pyridinesulfonamide",O=S(C1=C(C(F)(F)F)C=CC=N1)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O,rat,50,fc; food concentration,104 weeks,40,1.299999952,400,13.30000019
+3660,949,Flonicamid,Kuwahara,2002,DAR,2005,,Insecticide,158062-67-0,N-(cyanomethyl)-4-(trifluoromethyl)-3-pyridinecarboxamide,O=C(NCC#N)C1=CN=CC=C1C(F)(F)F,rat,52,fc; food concentration,104 weeks,200,7.320000172,1000,44.09999847
+4608,350,Florasulam,,,USA,2007,triazolopyrimidine sulfonanilide,herbicide,145701-23-1,"N-(2,6-difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide",FC1=CC=CC(F)=C1NS(C3=NN2C(OC)=NC=C(F)C2=N3)(=O)=O,rat,60,fd; food dose,104 weeks,0,250,0,500
+1012,291,Fluazifop-butyl,Amyes,1985,DAR,2007,2-(4aryloxyphenoxy)propionic acid,herbicide,79241-46-6,(2R)-2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acid,CC(C(OCCCC)=O)OC1=CC=C(OC2=CC=C(C(F)(F)F)C=N2)C=C1,rat,70,fc; food concentration,104 weeks,10,0.4699999988,80,3.789999962
+1013,65,Fluazinam,Chambers,1993,DAR,2006,"2,6-dinitroaniline",fungicide,79622-59-6,"3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2-pyridinamine",ClC1=C([N+]([O-])=O)C(NC2=NC=C(C(F)(F)F)C=C2Cl)=C([N+]([O-])=O)C=C1C(F)(F)F,rat,25,fc; food concentration,104 weeks,50,1.899999976,100,3.900000095
+3679,65,Fluazinam,Mayfield,1988,DAR,2006,"2,6-dinitroaniline",fungicide,79622-59-6,"3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2-pyridinamine",ClC1=C([N+]([O-])=O)C(NC2=NC=C(C(F)(F)F)C=C2Cl)=C([N+]([O-])=O)C=C1C(F)(F)F,rat,50,fc; food concentration,104 weeks,10,0.3799999952,100,3.819999933
+5923,1005,Flubendiamid,Enomoto,2004,JMPR,2010,amide,Insecticide,272451-65-7,"N2-[1,1-dimethyl-2-(methylsulfonyl)ethyl]-3-iodo-N1-[2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]-1,2-benzenedicarboxamide",O=C(NC2=CC=C(C(C(F)(F)F)(F)C(F)(F)F)C=C2C)C1=CC=CC(I)=C1C(NC(C)(C)CS(C)(=O)=O)=O,rat,25,fc; food concentration,52 weeks,50,2,2000,79
+5924,1005,Flubendiamid,Enomoto,2004,JMPR,2010,amide,Insecticide,272451-65-7,"N2-[1,1-dimethyl-2-(methylsulfonyl)ethyl]-3-iodo-N1-[2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]-1,2-benzenedicarboxamide",O=C(NC2=CC=C(C(C(F)(F)F)(F)C(F)(F)F)C=C2C)C1=CC=CC(I)=C1C(NC(C)(C)CS(C)(=O)=O)=O,rat,50,fc; food concentration,104 weeks,50,1.700000048,1000,34
+1014,2038,Flucarbazon,,,USA,2000,sulfonamide,Herbicide,145026-88-6,"4,5-dihydro-3-methoxy-4-methyl-5-oxo-N-[[2-(trifluoromethoxy)phenyl]sulfonyl]-1H-1,2,4-triazole-1-carboxamide",FC(F)(F)OC(C=CC=C2)=C2S(NC(N1C(N(C)C(OC)=N1)=O)=O)(=O)=O,rat,,fc; food concentration,104 weeks,0,125,0,1000
+5772,293,Flucythrinat,Brewer,1981,JMPR,1985,pyrethroid,insecticide,70124-77-5,cyano(3-phenoxyphenyl)methyl 4-(difluoromethoxy)-alpha-(1-methylethyl)benzeneacetate,CC(C(C3=CC=C(C=C3)OC(F)F)C(OC(C1=CC=CC(OC2=CC=CC=C2)=C1)C#N)=O)C,rat,50,fc; food concentration,104 weeks,30,0,60,0
+3691,138,Fludioxonil,Chang,1993,DAR,2006,"pyrrole, phenyl",fungicide,131341-86-1,"4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile",FC(O3)(F)OC(C3=CC=C2)=C2C1=CNC=C1C#N,rat,80,fc; food concentration,104 weeks,1000,37,3000,113
+6809,2108,Fluensulfon,Kaiser,2011,JMPR,2013,,Nematicide,318290-98-1,"5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]thiazole",,rat,50,fc; food concentration,104 weeks,30,1.399999976,200,9.600000381
+1016,343,Flufenacet,,,USA,1998,anilide,herbicide,142459-58-3,"N-(4-fluorophenyl)-N-(1-methylethyl)-2-{[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy}acetamide",FC(F)(F)C(S2)=NN=C2OCC(N(C(C)C)C1=CC=C(F)C=C1)=O,rat,,fc; food concentration,104 weeks,0,0,25,1.200000048
+3702,294,Flufenoxuron,Esdaile,1990,DAR,2008,"urea, benzoyl",insecticide,101463-69-8,"N-[[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]amino]carbonyl]-2,6-difluorobenzamide",FC1=C(NC(NC(C3=C(F)C=CC=C3F)=O)=O)C=CC(OC2=C(Cl)C=C(C(F)(F)F)C=C2)=C1,rat,30,fc; food concentration,104 weeks,500,22,5000,230
+3703,294,Flufenoxuron,Esdaile,1990,DAR,2008,"urea, benzoyl",insecticide,101463-69-8,"N-[[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]amino]carbonyl]-2,6-difluorobenzamide",FC1=C(NC(NC(C3=C(F)C=CC=C3F)=O)=O)C=CC(OC2=C(Cl)C=C(C(F)(F)F)C=C2)=C1,rat,50,fc; food concentration,104 weeks,500,22,5000,218
+5322,2076,Flumethrin,Bomhard,1987,JMPR,1996,pyrethroid,Acaricide,69770-45-2,"cyano(4-fluoro-3-phenoxyphenyl)methyl 3-[2-chloro-2-(4-chlorophenyl)ethenyl]-2,2-dimethylcyclopropanecarboxylate",O=C(OC(C#N)C3=CC(OC4=CC=CC=C4)=C(F)C=C3)C(C(C)2C)C2/C=C(Cl)/C1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,10,0.5,50,2.5
+1018,139,Flumioxazin,Anonymous,1993,DAR,2013,dicarboximide,herbicide,103361-09-7,"2-[7-fluoro-3,4-dihydro-3-oxo-4-(2-propynyl)-3H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione",O=C(C(CCCC4)=C4C3=O)N3C(C(F)=C2)=CC1=C2OCC(N1CC#C)=O,rat,74,fc; food concentration,104 weeks,50,1.799999952,500,18
+1019,1031,Fluometuron,Burdock,1982,DAR,2007,"urea, phenyl",Herbicide,2164-17-2,"N,N-dimethyl-N′-[3-(trifluoromethyl)phenyl]urea",FC(F)(F)C1=CC(NC(N(C)C)=O)=CC=C1,rat,60,fc; food concentration,104 weeks,10,0.5529999733,300,17.17300034
+1605,1031,Fluometuron,Hofmann,1966,DAR,2007,"urea, phenyl",Herbicide,2164-17-2,"N,N-dimethyl-N′-[3-(trifluoromethyl)phenyl]urea",FC(F)(F)C1=CC(NC(N(C)C)=O)=CC=C1,rat,25,gc; gavage concentration,52 weeks,0,10,0,30
+1020,468,Fluopicolid,Cooper,2003,DAR,2006,pyridine,fungicide,239110-15-7,"2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]benzamide",O=C(C2=C(Cl)C=CC=C2Cl)NCC1=NC=C(C(F)(F)F)C=C1Cl,rat,60,fc; food concentration,104 weeks,200,8.399999619,750,31.5
+6312,2052,Fluopyram,Kennel,2008,EU,2010,,Fungicide,658066-35-4,N-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-2-(trifluoromethyl)benzamide,O=C(NCCC2=NC=C(C(F)(F)F)C=C2Cl)C1=CC=CC=C1C(F)(F)F,rat,70,fc; food concentration,104 weeks,30,1.200000048,150,6
+1021,326,Fluoxastrobin,Schladt,2001,DAR,2005,strobilurin,fungicide,361377-29-9,"(1E)-[2-[[6-(2-chlorophenoxy)-5-fluoro-4-pyrimidinyl]oxy]phenyl](5,6-dihydro-1,4,2-dioxazin-3-yl)methanone O-methyloxime",CO\N=C(C4=NOCCO4)/C(C=CC=C3)=C3OC1=C(F)C(OC2=CC=CC=C2Cl)=NC=N1,rat,50,fc; food concentration,104 weeks,500,35,2500,181
+1022,163,Fluquinconazol,Scowen,1993,DAR,2006,triazole,fungicide,136426-54-5,"3-(2,4-dichlorophenyl)-6-fluoro-2-((1H)-1,2,4-triazol-1-yl)-4(3H)-quinazolinone",O=C2C1=CC(F)=CC=C1N=C(N4N=CN=C4)N2C3=C(Cl)C=C(Cl)C=C3,rat,50,fc; food concentration,104 weeks,10,0.4399999976,100,4.769999981
+1023,296,Flurochloridon,Sprague,1985,DAR,2006,others,herbicide,61213-25-0,3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]-2-pyrrolidinone,FC(F)(C1=CC=CC(N2CC(C(C2=O)Cl)CCl)=C1)F,rat,70,fc; food concentration,104 weeks,100,3.900000095,400,15.69999981
+1024,300,Fluroxypyr,,,USA,1998,"alkanoic acid, aryloxy",herbicide,69377-81-7,"[(4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]acetic acid",OC(COC1=C(C(N)=C(C(F)=N1)Cl)Cl)=O,rat,,fc; food concentration,104 weeks,0,100,0,500
+1025,1035,Flurprimidol,Kehr,1987,DAR,2007,pyrimidine,Plant growth regulator,56425-91-3,α-(1-methylethyl)-α-[4-(trifluoromethoxy)phenyl]-5-pyrimidinemethanol,CC(C)C(C2=CN=CN=C2)(O)C1=CC=C(OC(F)(F)F)C=C1,rat,60,fc; food concentration,104 weeks,90,3.599999905,300,9.800000191
+3734,1035,Flurprimidol,Kehr,1987,DAR,2007,pyrimidine,Plant growth regulator,56425-91-3,α-(1-methylethyl)-α-[4-(trifluoromethoxy)phenyl]-5-pyrimidinemethanol,CC(C)C(C2=CN=CN=C2)(O)C1=CC=C(OC(F)(F)F)C=C1,rat,30,fc; food concentration,78 weeks,0,0,1000,43.09999847
+1026,978,Flurtamon,,,UK,2000,others,Herbicide,96525-23-4,5-[methylamino]-2-phenyl-4-[3-(trifluoromethyl)phenyl]-3(2H)furanone,O=C1C(C3=CC=CC(C(F)(F)F)=C3)=C(NC)OC1C2=CC=CC=C2,rat,,fc; food concentration,104 weeks,0,2.839999914,0,18.39999962
+1027,333,Flusilazol,Pastoor,1986,JMPR,2007,triazole,fungicide,85509-19-9,"1-[[bis(4-fluorophenyl)(methyl)silyl]methyl]-1H-1,2,4-triazole",C[Si](C2=CC=C(C=C2)F)(C3=CC=C(F)C=C3)CN1C=NC=N1,rat,70,fc; food concentration,104 weeks,50,2,250,10
+4820,333,Flusilazol,Keller,1992,JMPR,2007,triazole,fungicide,85509-19-9,"1-[[bis(4-fluorophenyl)(methyl)silyl]methyl]-1H-1,2,4-triazole",C[Si](C2=CC=C(C=C2)F)(C3=CC=C(F)C=C3)CN1C=NC=N1,rat,65,fc; food concentration,104 weeks,0,0,125,5
+1028,2039,Fluthiacet,,,USA,1999,others,Herbicide,149253-65-6,"[[2-chloro-4-fluoro-5-[(tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]thio]acetic acid",ClC(C(SCC(O)=O)=C3)=CC(F)=C3\N=C2/SC(N1CCCCN12)=O,rat,,fc; food concentration,104 weeks,50,2.099999905,3000,130
+6895,2019,Flutianil,Anonymous,2009,DAR,2013,others,Fungicide,958647-10-4,(2Z)-2-[[2-fluoro-5-(trifluoromethyl)phenyl]thio]-2-[3-(2-methoxyphenyl)-2-thiazolidinylidene]acetonitrile,COC1=C(N3/C(SCC3)=C(C#N)/SC2=CC(C(F)(F)F)=CC=C2F)C=CC=C1,rat,63,fc; food concentration,104 weeks,6000,249,0,0
+2801,94,Flutolanil,Katoh,1982,DAR,2006,anilide,fungicide,66332-96-5,N-[3-(1-methylethoxy)phenyl]-2-(trifluoromethyl)benzamide,O=C(NC2=CC(OC(C)C)=CC=C2)C1=C(C(F)(F)F)C=CC=C1,rat,50,fc; food concentration,104 weeks,200,8.699999809,2000,87
+3742,335,Flutriafol,Milburn,1986,DAR,2006,triazole,fungicide,76674-21-0,"(+-)-alpha-(2-fluorophenyl)-alpha-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol",OC(C2=CC=C(F)C=C2)(C3=C(F)C=CC=C3)CN1C=NC=N1,rat,64,fc; food concentration,104 weeks,20,1.049999952,200,10.19999981
+6177,2109,Fluxapyroxad,Buesen,2009,DAR,2011,pyrazole,Fungicide,907204-31-3,"3-(difluoromethyl)-1-methyl-N-(3′,4′,5′-trifluoro[1,1′-biphenyl]-2-yl)-1H-pyrazole-4-carboxamide",,rat,60,fc; food concentration,104 weeks,50,2.099999905,250,0
+3755,338,Folpet,Crown,1989,DAR,2005,N-trihalomethylthio,fungicide,133-07-3,"2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",O=C2N(SC(Cl)(Cl)Cl)C(C1=CC=CC=C12)=O,rat,20,fc; food concentration,104 weeks,250,11.39999962,1500,0
+3756,338,Folpet,Crown,1985,DAR,2005,N-trihalomethylthio,fungicide,133-07-3,"2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",O=C2N(SC(Cl)(Cl)Cl)C(C1=CC=CC=C12)=O,rat,60,fc; food concentration,104 weeks,0,0,500,25
+3757,338,Folpet,Cox,1985,DAR,2005,N-trihalomethylthio,fungicide,133-07-3,"2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",O=C2N(SC(Cl)(Cl)Cl)C(C1=CC=CC=C12)=O,rat,50,fc; food concentration,104 weeks,800,40,3200,0
+1032,2046,Fomesafen,,,UK,1995,amide,Herbicide,72178-02-0,5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitrobenzamide,ClC1=CC(C(F)(F)F)=CC=C1OC2=CC=C([N+]([O-])=O)C(C(NS(C)(=O)=O)=O)=C2,rat,,fc; food concentration,104 weeks,0,0.25,0,5
+4649,316,Foramsulfuron,Higgs,2000,DAR,2001,"urea, sulfonyl",Herbicide,173159-57-4,"2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-4-(formylamino)-N,N-dimethylbenzamide",O=CNC1=CC=C(C(N(C)C)=O)C(S(NC(NC2=NC(OC)=CC(OC)=N2)=O)(=O)=O)=C1,rat,70,fc; food concentration,104 weeks,20000,849,0,0
+1033,989,Forchlorfenuron,,,USA,2004,urea,Plant growth regulator,68157-60-8,N-(2-chloro-4-pyridinyl)-N′-phenylurea,ClC1=CC(NC(NC2=CC=CC=C2)=O)=CC=N1,rat,,fc; food concentration,104 weeks,150,7,2000,93
+1034,1024,Formetanat,Mallyon,1988,DAR,2005,carbamate,Acaricide,23422-53-9,"N,N-dimethyl-N′-[3-[[(methylamino)carbonyl]oxy]phenyl]methanimidamide",CNC(OC1=CC=CC(/N=C/N(C)C)=C1)=O,rat,50,fc; food concentration,104 weeks,50,2.299999952,250,11.5
+1035,351,Fosetyl-Aluminium,Spicer,1981,DAR,2005,organophosphorus,fungicide,39148-24-8,ethyl hydrogen phosphonate,[O-]P(OCC)([H])=O.[O-]P(OCC)([H])=O.[O-]P(OCC)([H])=O.[Al+3],rat,80,fc; food concentration,104 weeks,8000,348,30000,1305
+1036,984,Fosthiazat,,,USA,2004,organophosphorus,Nematicide,98886-44-3,O-ethyl S-(1-methylpropyl) (2-oxo-3-thiazolidinyl)phosphonothioate,O=C1N(P(OCC)(SC(C)CC)=O)CCS1,rat,,fc; food concentration,104 weeks,0,0,1,0.3799999952
+1037,354,Fuberidazol,Eiben,1993,DAR,2006,benzimidazole,fungicide,3878-19-1,2-(2-furanyl)-1H-bezimidazole,C2(C3=CC=CO3)=NC1=CC=CC=C1N2,rat,60,fc; food concentration,104 weeks,80,4.599999905,400,23
+1038,2040,Furfural,NTP,1990,USA,2006,others,Fungicide,98-01-1,2-furancarboxaldehyde,O=CC1=CC=CO1,rat,,fc; food concentration,104 weeks,0,30,0,60
+3793,303,Glufosinat,Suter,1986,DAR,2004,"amino acid, phosphinico",herbicide,51276-47-2,(+/-)-2-amino-4-(hydroxymethylphosphinyl)butanoic acid,CP(CCC(N)C(O)=O)(O)=O,rat,80,fc; food concentration,130 weeks,500,24.39999962,0,0
+3794,303,Glufosinat,Schmidt,1998,DAR,2004,"amino acid, phosphinico",herbicide,51276-47-2,(+/-)-2-amino-4-(hydroxymethylphosphinyl)butanoic acid,CP(CCC(N)C(O)=O)(O)=O,rat,60,fc; food concentration,104 weeks,1000,57.09999847,5000,228.8999939
+1040,309,Glyphosat,Stout,1990,JMPR,2004,"amino acid, phosphinico",herbicide,1071-83-6,N-(phosphonomethyl)glycine,OC(CNCP(O)(O)=O)=O,rat,60,fd; food dose,104 weeks,8000,362,20000,940
+4976,309,Glyphosat,Milburn,1996,JMPR,2004,"amino acid, phosphinico",herbicide,1071-83-6,N-(phosphonomethyl)glycine,OC(CNCP(O)(O)=O)=O,rat,24,fc; food concentration,52 weeks,2000,141,8000,560
+4977,309,Glyphosat,Atkinson,1993,JMPR,2004,"amino acid, phosphinico",herbicide,1071-83-6,N-(phosphonomethyl)glycine,OC(CNCP(O)(O)=O)=O,rat,85,fd; food dose,104 weeks,0,100,0,300
+4978,309,Glyphosat,Brammer,2001,JMPR,2004,"amino acid, phosphinico",herbicide,1071-83-6,N-(phosphonomethyl)glycine,OC(CNCP(O)(O)=O)=O,rat,52,fc; food concentration,104 weeks,6000,361,20000,1214
+1041,310,Guazatine,Heath,1991,DAR,2007,guanidine,fungicide,108173-90-6,guazatine,NC(NCCCCCCCCNC(N)=N)=N,rat,50,fc; food concentration,104 weeks,150,8,350,18.5
+6347,2104,Halosulfuron-methyl,not given,1992,EU,2011,pyrazole,Herbicide,100784-20-1,,,rat,85,fc; food concentration,105 weeks,1000,56.29999924,2500,0
+3844,96,Haloxyfop,Yano,1984,DAR,2009,2-(4aryloxyphenoxy)propionic acid,herbicide,72619-32-0,(+-)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acid,CC(C(O)=O)OC2=CC=C(C=C2)OC1=C(Cl)C=C(C(F)(F)F)C=N1,rat,90,fd; food dose,104 weeks,0,0.06499999762,0,0.1000000015
+5111,314,"HCH, gamma- (Lindan)",Amyes,1990,JMPR,2002,organochlorine,insecticide,58-89-9,,ClC1C(Cl)C(Cl)C(Cl)C(Cl)C1Cl,rat,50,fc; food concentration,52 weeks,10,0.4699999988,100,4.699999809
+5661,70,Hexaconazol,Hext,1988,JMPR,1990,triazole,fungicide,79983-71-4,"(+-)-alpha-butyl-alpha-(2,4-dichlorophenyl)-1H-1,2,4-triazole-1-ethanol",CCCCC(CN1C=NC=N1)(C2=CC=C(C=C2Cl)Cl)O,rat,64,fc; food concentration,104 weeks,10,0.4699999988,100,0
+1043,364,Hexythiazox,Spicer,1984,DAR,2006,carboxamide,acaricide,78587-05-0,trans-5-(4-chlorophenyl--N-cyclohexyl-4-methyl-2-oxo-3-thiazolidinecarboxamide,CC1C(C3=CC=C(C=C3)Cl)SC(N1C(NC2CCCCC2)=O)=O,rat,80,fc; food concentration,104 weeks,60,3.200000048,430,23.10000038
+5811,2501,Hydramethylnon,,,USA,,,,,,,rat,50,fc; food concentration,104 weeks,50,2.400000095,100,4.900000095
+3822,964,Hymexazol,Barker,1992,DAR,2007,,Fungicide,10004-44-1,5-methyl-3(2H)-isoxazolone,OC1=NOC(C)=C1,rat,70,fc; food concentration,104 weeks,400,20,2000,99
+3895,365,Imazalil,Lina,1984,DAR,2009,imidazole,fungicide,35554-44-0,"(+/-)-1-[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole",ClC(C=C(Cl)C=C2)=C2C(OCC=C)CN1C=NC=C1,rat,,,78 weeks,0,3.900000095,0,15.89999962
+3896,365,Imazalil,Til,1985,DAR,2009,imidazole,fungicide,35554-44-0,"(+/-)-1-[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole",ClC(C=C(Cl)C=C2)=C2C(OCC=C)CN1C=NC=C1,rat,,,130 weeks,0,3.599999905,0,15
+4664,366,Imazamox,,,USA,1997,imidazolinone,herbicide,114311-32-9,"(+/-)-2-[4,5-dihydro-4-methyl-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5-(methoxymethyl)-3-pyridine carboxylic acid",O=C(O)C1=C(C2=NC(C)(C(C)C)C(N2)=O)N=CC(COC)=C1,rat,,fc; food concentration,104 weeks,20000,1167,0,0
+6818,2819,Imazapic,Fischer,1994,JMPR,2013,imidazolinone,Herbicide,104098-48-8,"2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5-methyl-3-pyridinecarboxylic acid",,rat,65,fc; food concentration,104 weeks,20000,1029,0,0
+6827,2508,Imazapyr,Daly,1988,JMPR,2013,imidazolinone,Herbicide,81334-34-1,"2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-3-pyridinecarboxylic acid",,rat,65,fc; food concentration,104 weeks,10000,503,0,0
+1044,2008,Imazaquin,Dickie,1985,DAR,2008,imidazolinone,Herbicide,81335-37-7,"2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-3-quinolinecarboxylic acid",O=C(O)C2=C(N=C(C=CC=C3)C3=C2)C(N1)=NC(C)(C(C)C)C1=O,rat,65,fc; food concentration,104 weeks,5000,250,10000,500
+1045,2047,Imazethapyr,,,UK,1996,imidazolinone,Herbicide,81335-77-5,"2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5-ethyl-3-pyridinecarboxylic acid",CCC1=CC(C(O)=O)=C(C2=NC(C)(C(C)C)C(N2)=O)N=C1,rat,,fc; food concentration,104 weeks,0,43.5,0,0
+6214,987,Imazosulfuron,Atkinson,1991,DAR,1998,"urea, sulfonyl",Herbicide,122548-33-8,"2-chloro-N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]imidazo[1,2-a]pyridine-3-sulfonamide",COC1=NC(NC(NS(C2=C(Cl)N=C3N2C=CC=C3)(=O)=O)=O)=NC(OC)=C1,rat,80,fc; food concentration,104 weeks,2000,106.0999985,20000,0
+3940,98,Imidacloprid,Eiben,1991,DAR,2006,pyridine,insecticide,138261-41-3,1-[(6-chloro-3-pyridinyl)methyl]-N-nitro-2-imidazolidinimine,ClC2=CC=C(C=N2)CN1CCN/C1=N\[N+]([O-])=O,rat,50,fc; food concentration,104 weeks,100,5.699999809,300,24.89999962
+6226,2015,Indaziflam,,,USA,2010,triazine,Herbicide,950782-86-2,"N-[(1R,2S)-2,3-dihydro-2,6-dimethyl-1H-inden-1-yl]-6-(1-fluoroethyl)-1,3,5-triazine-2,4-diamine",CC1=CC=C(CC3C)C(C3NC2=NC(N)=NC(C(F)C)=N2)=C1,rat,,fc; food concentration,104 weeks,300,12,3000,0
+1047,355,Indoxacarb,,,JMPR,2005,carbamate,insecticide,173584-44-6,"(S)-methyl 7-chloro-2.5-dihydro-2[[(methoxy-carbonyl) [4-(trifluoromethoxy)phenyl]amino] carbonyl-indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate",ClC1=CC=C(C2=NN(C(N(C(OC)=O)C4=CC=C(OC(F)(F)F)C=C4)=O)COC(C(OC)=O)2C3)C3=C1,rat,72,fc; food concentration,104 weeks,60,2.099999905,125,3.599999905
+6597,311,Iodosulfuron-methyl-Natrium,Wason,1998,DAR,2000,"urea, triazinylsulfonyl",herbicide,144550-36-7,"Methyl-4-iodo-2-[3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-uriedo-sulfonyl)-benzoate, sodium salt",IC1=CC=C(C(OC)=O)C(S([N-]C(NC2=NC(C)=NC(OC)=N2)=O)(=O)=O)=C1.[Na+],rat,70,fc; food concentration,104 weeks,70,2.960000038,700,29.70000076
+6442,2041,Ipconazol,Anonymous,2006,DAR,2011,triazole,Fungicide,125225-28-7,"2-[(4-chlorophenyl)methyl]-5-(1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol",OC(C(C(C)C)CC2)(CN3N=CN=C3)C2CC1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,300,13.30000019,0,0
+5332,368,Iprodion,Chambers,1992,JMPR,1995,dicarboximide,fungicide,36734-19-7,"3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide",CC(NC(N1CC(N(C2=CC(Cl)=CC(Cl)=C2)C1=O)=O)=O)C,rat,60,fc; food concentration,52 weeks,150,6,300,12
+5625,368,Iprodion,Hastings,1976,JMPR,1992,dicarboximide,fungicide,36734-19-7,"3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide",CC(NC(N1CC(N(C2=CC(Cl)=CC(Cl)=C2)C1=O)=O)=O)C,rat,60,fc; food concentration,104 weeks,1000,0,0,0
+6562,371,Isoproturon,Heisler,1990,DAR,1999,"urea, phenyl",herbicide,34123-59-6,"N,N-dimethyl-N'-[4-(1-methylethyl)phenyl]urea",CC(C)C1=CC=C(NC(N(C)C)=O)C=C1,rat,50,fc; food concentration,130 weeks,0,0,100,0
+6563,371,Isoproturon,Hunter,1981,DAR,1999,"urea, phenyl",herbicide,34123-59-6,"N,N-dimethyl-N'-[4-(1-methylethyl)phenyl]urea",CC(C)C1=CC=C(NC(N(C)C)=O)C=C1,rat,50,fc; food concentration,104 weeks,80,3.099999905,400,0
+6184,2022,Isopyrazam,Milburn,2008,DAR,2011,pyrazole,Fungicide,881685-58-1,"3-(difluoromethyl)-1-methyl-N-[1,2,3,4-tetrahydro-9-(1-methylethyl)-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide",CC(C)C1C2CCC1C3=C2C(NC(C4=CN(C)N=C4C(F)F)=O)=CC=C3,rat,64,fc; food concentration,104 weeks,0,0,100,5.5
+1050,1044,Isoxaben,Gries,1987,DAR,2006,amide,Herbicide,82558-50-7,"N-[3-(1-ethyl-1-methylpropyl)-5-isoxazolyl]-2,6-dimethoxybenzamide",COC1=CC=CC(OC)=C1C(NC2=CC(C(CC)(C)CC)=NO2)=O,rat,60,fc; food concentration,104 weeks,1250,51,12500,527
+3965,1044,Isoxaben,Lake,1985,DAR,2006,amide,Herbicide,82558-50-7,"N-[3-(1-ethyl-1-methylpropyl)-5-isoxazolyl]-2,6-dimethoxybenzamide",COC1=CC=CC(OC)=C1C(NC2=CC(C(CC)(C)CC)=NO2)=O,rat,30,fc; food concentration,52 weeks,1250,58,12500,600
+4701,360,Isoxaflutol,Chase,1995,JMPR,2013,triketone,herbicide,141112-29-0,(5-cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone,FC(F)(F)C(C=C3S(C)(=O)=O)=CC=C3C(C1=C(C2CC2)ON=C1)=O,rat,75,fd; food dose,104 weeks,0,2,0,20
+4717,2165,Kasugamycin,,,USA,2005,,Bactericide,6980-18-3,"3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-D-chiro-inositol",,rat,,fc; food concentration,104 weeks,300,11.30000019,3000,116
+5890,148,Kresoxim-methyl,Kamp,2008,DAR,2010,strobilurin,fungicide,143390-89-0,(E)-alpha-(methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetic acid methyl ester,COC(/C(C(C=CC=C2)=C2COC1=C(C)C=CC=C1)=N/OC)=O,rat,,fc; food concentration,104 weeks,0,0,16000,752.0999756
+5891,148,Kresoxim-methyl,Mellert,1994,DAR,2010,strobilurin,fungicide,143390-89-0,(E)-alpha-(methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetic acid methyl ester,COC(/C(C(C=CC=C2)=C2COC1=C(C)C=CC=C1)=N/OC)=O,rat,70,fc; food concentration,104 weeks,800,36,8000,375
+3970,373,Lenacil,Thirlwell,2002,DAR,2008,uracil,herbicide,2164-08-1,"3-cyclohexyl-6,7-dihydro-1H-cyclopentapyrimidine-2,4(3H,5H)-dione",O=C2NC1=C(C(N2C3CCCCC3)=O)CCC1,rat,20,fc; food concentration,52 weeks,2500,139.1000061,25000,0
+3971,373,Lenacil,Thirlwell,2002,DAR,2008,uracil,herbicide,2164-08-1,"3-cyclohexyl-6,7-dihydro-1H-cyclopentapyrimidine-2,4(3H,5H)-dione",O=C2NC1=C(C(N2C3CCCCC3)=O)CCC1,rat,50,fc; food concentration,104 weeks,250,12,2500,118
+1052,374,Linuron,,,USA,1995,urea,herbicide,330-55-2,"N'-(3,4-dichlorophenyl)-1-methoxy-1-methylurea",O=C(NC1=CC(Cl)=C(Cl)C=C1)N(C)OC,rat,,fc; food concentration,104 weeks,50,2.5,125,6.25
+6381,374,Linuron,,,USA,1995,urea,herbicide,330-55-2,"N'-(3,4-dichlorophenyl)-1-methoxy-1-methylurea",O=C(NC1=CC(Cl)=C(Cl)C=C1)N(C)OC,rat,,fc; food concentration,104 weeks,125,6.25,625,31.25
+6382,374,Linuron,,,USA,1995,urea,herbicide,330-55-2,"N'-(3,4-dichlorophenyl)-1-methoxy-1-methylurea",O=C(NC1=CC(Cl)=C(Cl)C=C1)N(C)OC,rat,,fc; food concentration,78 weeks,25,1.25,125,6.25
+1053,119,Lufenuron,Bachmann,1993,DAR,2007,"urea, benzoyl",insecticide,103055-07-8,"N-[[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenil]amino]carbonyl]-2,6-difluorobenzamide",O=C(NC(NC2=CC(Cl)=C(OC(F)(F)C(F)C(F)(F)F)C=C2Cl)=O)C1=C(F)C=CC=C1F,rat,80,fc; food concentration,104 weeks,50,1.929999948,500,20.39999962
+4005,377,Malathion,Daly,1996,DAR,2004,organophosphorus,insecticide,121-75-5,diethyl [(dimethoxyphosphinothioyl)thio]butanedioate,O=C(OCC)C(CC(OCC)=O)SP(OC)(OC)=S,rat,90,fc; food concentration,104 weeks,50,3,500,29
+4007,377,Malathion,Rucci,1980,DAR,2004,organophosphorus,insecticide,121-75-5,diethyl [(dimethoxyphosphinothioyl)thio]butanedioate,O=C(OCC)C(CC(OCC)=O)SP(OC)(OC)=S,rat,50,fc; food concentration,104 weeks,100,17,1000,143
+4398,99,Maleinsäurehydrazid,Van der Heijden,1981,DAR,1997,others,plant growth regulator,10071-13-3;123-33-1,"1,2-dihydro-3,6-pyridazinedione",OC1=CC=C(O)N=N1,rat,55,fc; food concentration,120 weeks,0,0,10000,0
+4399,99,Maleinsäurehydrazid,Perry,1991,DAR,1997,others,plant growth regulator,10071-13-3;123-33-1,"1,2-dihydro-3,6-pyridazinedione",OC1=CC=C(O)N=N1,rat,70,fd; food dose,104 weeks,0,25,0,500
+1056,378,Mancozeb,Stadler,1990,JMPR,1993,dithiocarbamate,fungicide,8018-01-7,"[[1,2-ethanediylbis[carbamodithioato]](2-)]manganese mixture with [[1,2-ethanediylbis[carbamodithioato]](2-)]zinc",S=C1S[Mn+2]SC(NCCN1)=S,rat,72,fc; food concentration,104 weeks,125,4.800000191,750,28.79999924
+5519,378,Mancozeb,Hooks,1992,JMPR,1993,dithiocarbamate,fungicide,8018-01-7,"[[1,2-ethanediylbis[carbamodithioato]](2-)]manganese mixture with [[1,2-ethanediylbis[carbamodithioato]](2-)]zinc",S=C1S[Mn+2]SC(NCCN1)=S,rat,70,fc; food concentration,104 weeks,100,4,400,0
+1057,946,Mandipropamid,Pinto,2005,DAR,2008,amide,Fungicide,374726-62-2,4-chloro-N-[2-[3-methoxy-4-(2-propynyloxy)phenyl]ethyl]-a-(2-propynyloxy)benzeneacetamide,C#CCOC(C(NCCC2=CC=C(OCC#C)C(OC)=C2)=O)C1=CC=C(Cl)C=C1,rat,64,fc; food concentration,104 weeks,50,3,250,15.19999981
+5510,379,Maneb,Leuschner,1979,JMPR,1993,dithiocarbamate,fungicide,12427-38-2,"[1,2-ethanediylbis[carbamodithioato](2-)]manganese",[S]C(NCCNC(S[Mn])=S)=S,rat,90,fc; food concentration,130 weeks,300,20,1000,67
+7039,375,MCPA,Kirsch,1988,JMPR,2012,"alkanoic acid, aryloxy",herbicide,94-74-6,(4-chloro-2-methylphenoxy)acetic acid,O=C(O)COC(C=CC(Cl)=C1)=C1C,rat,50,fc; food concentration,104 weeks,80,4.800000191,320,19
+1058,381,Mecoprop,,,UK,1994,"propionic acid, aryloxyphenoxy",herbicide,7085-19-0,(+/-)-2-(4-chloro-2-methylphenoxy)propanoic acid,O=C(O)C(C)OC1=C(C)C=C(Cl)C=C1,rat,,fc; food concentration,104 weeks,0,1.100000024,0,5.5
+4036,325,Mepiquat chlorid,Mellert,1994,DAR,2006,quaternary ammonium,plant growth regulator,24307-26-4,"1,1-dimethylpiperidinium chloride",C[N+]1(C)CCCCC1.[Cl-],rat,20,fc; food concentration,104 weeks,2316,106,5790,268
+4038,325,Mepiquat chlorid,Leuschner,1979,DAR,2006,quaternary ammonium,plant growth regulator,24307-26-4,"1,1-dimethylpiperidinium chloride",C[N+]1(C)CCCCC1.[Cl-],rat,100,fc; food concentration,104 weeks,3000,186,9000,684
+4052,1612,Meptyldinocap,Ferguson,1999,DAR,2008,dinitrophenol,Fungicide,131-72-6,"2-(1-methylheptyl)-4,6-dinitrophenyl (2E)-2-butenoate",CC(CCCCCC)C1=C(OC(/C=C\C)=O)C([N+]([O-])=O)=CC([N+]([O-])=O)=C1,rat,20,fc; food concentration,52 weeks,200,11.5,2000,120.8000031
+4053,1612,Meptyldinocap,Maita,1980,DAR,2008,dinitrophenol,Fungicide,131-72-6,"2-(1-methylheptyl)-4,6-dinitrophenyl (2E)-2-butenoate",CC(CCCCCC)C1=C(OC(/C=C\C)=O)C([N+]([O-])=O)=CC([N+]([O-])=O)=C1,rat,80,fc; food concentration,130 weeks,200,6.400000095,2000,71
+4733,370,Mesosulfuron-methyl,,,USA,2004,"urea, sulfonyl",herbicide,208465-21-8,"methyl, 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-4-[[(methylsulfonyl)amino]methyl]benzoic acid",O=S(NCC1=CC=C(C(OC)=O)C(S(NC(NC2=NC(OC)=CC(OC)=N2)=O)(=O)=O)=C1)(C)=O,rat,,fc; food concentration,104 weeks,0,764,0,0
+6471,307,Mesotrione,Brammer,1997,DAR,2004,triketone,herbicide,104206-82-8,"2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione",O=C(C2=CC=C(S(=O)(C)=O)C=C2[N+]([O-])=O)C1C(CCCC1=O)=O,rat,64,fc; food concentration,104 weeks,0,0,7.5,0.4799999893
+6765,1008,Metaflumizon,Kelly,2003,DAR,2009,urea,Insecticide,139968-49-3,2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]hydrazinecarboxamide,O=C(NC3=CC=C(OC(F)(F)F)C=C3)N/N=C(C2=CC=C(C(F)(F)F)C=C2)/CC1=CC=C(C#N)C=C1,rat,80,gd; gavage dose,104 weeks,0,60,0,200
+5126,383,Metalaxyl,Ahby,1980,JMPR,2002,arylalanine,fungicide,57837-19-1,"methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-DL-alaninate",CC1=C(N(C(C(OC)=O)C)C(COC)=O)C(C)=CC=C1,rat,80,fc; food concentration,104 weeks,1250,43,0,0
+4063,102,Metaldehyd,Gill,1992,DAR,2006,others,molluscicide,108-62-3,"2,4,6,8-tetramethyl-1,3,5,7-tetraoxacyclo-octane",CC1OC(C)OC(C)OC(C)O1,rat,60,fc; food concentration,104 weeks,50,2,1000,44
+4064,102,Metaldehyd,Verschuuren,1975,DAR,2006,others,molluscicide,108-62-3,"2,4,6,8-tetramethyl-1,3,5,7-tetraoxacyclo-octane",CC1OC(C)OC(C)OC(C)O1,rat,25,fc; food concentration,108 weeks,0,0,200,0
+1061,1037,Metam,Rattray,1994,DAR,2007,dithiocarbamate,Fungicide,144-54-7,methylcarbamodithioic acid,S=C(S)NC,rat,64,wc; water concentration,104 weeks,19,1.5,56,4.300000191
+1062,384,Metamitron,Leser,1998,DAR,2007,"1,2,4-triazinone",herbicide,41394-05-2,"4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one",O=C1C(C2=CC=CC=C2)=NN=C(C)N1N,rat,60,fc; food concentration,104 weeks,100,4.900000095,400,19.5
+4082,384,Metamitron,Bomhard,1978,DAR,2007,"1,2,4-triazinone",herbicide,41394-05-2,"4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one",O=C1C(C2=CC=CC=C2)=NN=C(C)N1N,rat,50,fc; food concentration,104 weeks,250,13.30000019,1250,74.59999847
+1063,385,Metazachlor,Krishnappa,2002,DAR,2005,imidazole,herbicide,67129-08-2,"2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide",O=C(N(C2=C(C)C=CC=C2C)CN1N=CC=C1)CCl,rat,80,fc; food concentration,104 weeks,200,8.5,2000,87
+4098,385,Metazachlor,Hunter,1983,DAR,2005,imidazole,herbicide,67129-08-2,"2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide",O=C(N(C2=C(C)C=CC=C2C)CN1N=CC=C1)CCl,rat,75,fc; food concentration,113 weeks,0,0,500,17.60000038
+4099,385,Metazachlor,Hunter,1983,DAR,2005,imidazole,herbicide,67129-08-2,"2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide",O=C(N(C2=C(C)C=CC=C2C)CN1N=CC=C1)CCl,rat,75,fc; food concentration,104 weeks,100,3.200000048,0,0
+1064,140,Metconazol,Taupin,1992,DAR,2005,triazole,fungicide,125116-23-6,"5-[(4-chlorophenyl)methyl]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol",OC1(CN3C=NC=N3)C(C)(C)CCC1CC2=CC=C(Cl)C=C2,rat,30,fc; food concentration,104 weeks,100,4.300000191,300,13.10000038
+4136,140,Metconazol,Taupin,1992,DAR,2005,triazole,fungicide,125116-23-6,"5-[(4-chlorophenyl)methyl]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol",OC1(CN3C=NC=N3)C(C)(C)CCC1CC2=CC=C(Cl)C=C2,rat,50,fc; food concentration,104 weeks,100,4.599999905,300,13.80000019
+1065,388,Methamidophos,Hayes,1984,JMPR,2002,organophosphorus,insecticide,10265-92-6,"O,S-dimethyl phosphoramidothioate",O=P(SC)(OC)N,rat,50,fc; food concentration,104 weeks,2,0.1000000015,6,0.2899999917
+1066,390,Methidathion,Johnston,1967,JMPR,1992,organophosphorus,insecticide,950-37-8,"S-[(5-methoxy-2-oxo-1,2,4-thiadiazol-3(2H)-yl)methyl] O,O-dimethyl phosphorodithioate",S=P(OC)(OC)SCN1C(SC(OC)=N1)=O,rat,25,fc; food concentration,104 weeks,4,0.1599999964,16,0.6399999857
+5611,390,Methidathion,Yau,1986,JMPR,1992,organophosphorus,insecticide,950-37-8,"S-[(5-methoxy-2-oxo-1,2,4-thiadiazol-3(2H)-yl)methyl] O,O-dimethyl phosphorodithioate",S=P(OC)(OC)SCN1C(SC(OC)=N1)=O,rat,65,fc; food concentration,104 weeks,4,0.1599999964,40,1.720000029
+1067,391,Methiocarb,Krötlinger,1981,DAR,2005,carbamate,insecticide,2032-65-7,"3,5-dimethyl-4-(methylthio)phenyl methylcarbamate",O=C(OC1=CC(C)=C(SC)C(C)=C1)NC,rat,60,fc; food concentration,104 weeks,200,9.300000191,600,28
+1068,392,Methomyl,Kaplan,1981,DAR,2004,"carbamate, oxime",insecticide,16752-77-5,methyl N-[[(methylamino)carbonyl]oxy]ethanimidothioate,CNC(O/N=C(C)\SC)=O,rat,80,fc; food concentration,104 weeks,100,4.800000191,400,19.20000076
+5145,2079,Methopren,Wazeter,1975,JMPR,2001,others,Insecticide,40596-69-8,"1-methylethyl (2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate",CC(C)OC(/C=C(C)/C=C/CC(C)CCCC(C)(C)OC)=O,rat,50,fc; food concentration,104 weeks,1000,50,5000,250
+1069,356,Methoxyfenozid,Anderson,1998,JMPR,2003,others,insecticide,161050-58-4,"Benzoic acid, 3-methoxy-2-methyl-, 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl) hydrazide",CC1=C(OC)C=CC=C1C(NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O)=O,rat,70,fc; food concentration,104 weeks,200,10,8000,411
+4159,103,Methylbromid,Mertens,1997,DAR,2006,others,insecticide,74-83-9,bromomethane,BrC([H])([H])[H],rat,70,cc; capsule concentration,104 weeks,50,2.200000048,250,11
+4160,103,Methylbromid,Mitsumori,1990,DAR,2006,others,insecticide,74-83-9,bromomethane,BrC([H])([H])[H],rat,60,fc; food concentration,104 weeks,200,7,500,17
+1070,395,Metiram,Hunter,1981,JMPR,1993,"dithiocarbamate, alkylenebis",fungicide,9006-42-2,metiram (composition not specified),"[S]C(NCCNC(S[Zn])=S)=S.[S]C(NCCNC(S[Zn])=S)=S.N.N.[F,Cl,Br,I]",rat,50,fc; food concentration,104 weeks,80,3.099999905,320,12.30000019
+6875,396,Metobromuron,Kirsch,1986,DAR,2012,"urea, phenyl",herbicide,3060-89-7,N'-(4-bromophenyl)-N-methoxy-N-methylurea,BrC1=CC=C(NC(N(C)OC)=O)C=C1,rat,60,fc; food concentration,104 weeks,50,3.099999905,150,3.720000029
+1071,2042,Metofluthrin,,,USA,2006,,,240494-70-6,"[2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl 2,2-dimethyl-3-(1-propenyl)cyclopropanecarboxylate",COCC1=C(F)C(F)=C(COC(C2C(/C=C/C)C(C)2C)=O)C(F)=C1F,rat,,fc; food concentration,104 weeks,200,8.199999809,900,38.09999847
+6395,397,"Metolachlor, S-",Sorenson,1983,USA,1995,chloroacetanilide,herbicide,87392-12-9,(S)-2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-metylethyl)acetamide,O=C(N(C1=C(C)C=CC=C1CC)C(C)COC)CCl,rat,60,fc; food concentration,104 weeks,300,15,3000,150
+1072,141,Metosulam,Zempel,1992,DAR,2009,triazolopyrimidine sulfonanilide,herbicide,139528-85-1,"N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide",CC1=C(Cl)C(NS(C2=NN3C(N=C(OC)C=C3OC)=N2)(=O)=O)=C(Cl)C=C1,rat,60,fd; food dose,104 weeks,0,5,0,30
+1073,947,Metrafenon,Kelly,2002,DAR,2005,benzophenone,Fungicide,220899-03-6,"(3-bromo-6-methoxy-2-methylphenyl)(2,3,4-trimethoxy-6-methylphenyl)methanone",BrC1=C(C)C(C(C2=C(C)C=C(OC)C(OC)=C2OC)=O)=C(OC)C=C1,rat,65,fc; food concentration,104 weeks,500,25,5000,260
+1074,400,Metribuzin,Christenson,1993,DAR,2005,"1,2,4-triazinone",herbicide,21087-64-9,"4-amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one",O=C1C(C(C)(C)C)=NN=C(SC)N1N,rat,50,fc; food concentration,104 weeks,30,1.299999952,300,13
+4183,400,Metribuzin,Löser,1974,DAR,2005,"1,2,4-triazinone",herbicide,21087-64-9,"4-amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one",O=C1C(C(C)(C)C)=NN=C(SC)N1N,rat,40,fc; food concentration,104 weeks,100,5.300000191,300,14.39999962
+4184,400,Metribuzin,Deshmukh,2000,DAR,2005,"1,2,4-triazinone",herbicide,21087-64-9,"4-amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one",O=C1C(C(C)(C)C)=NN=C(SC)N1N,rat,80,wc; water concentration,104 weeks,20,1.600000024,100,0
+7060,401,Metsulfuron-methyl,Hamada,1985,DAR,2013,"urea, triazinylsulfonyl",herbicide,74223-64-6,"methyl-2-[[[[(4-methoxy-6-methyl-1,3,5-triazin-zyl)-amino]carbonyl]amino]sulfonil]benzoate",O=C(OC)C1=CC=CC=C1S(NC(NC2=NC(C)=NC(OC)=N2)=O)(=O)=O,rat,90,fc; food concentration,104 weeks,500,23,5000,119
+1075,152,Mevinphos,Plutnick,1994,JMPR,1996,organophosphorus,insecticide,7786-34-7,methyl 3-[(dimethoxyphosphinyl)oxy]-2-butenoate,O=P(OC)(OC)O/C(C)=C/C(OC)=O,rat,80,gd; gavage dose,104 weeks,0,0.02500000037,0,0.349999994
+6135,934,Milbemectin,Matsunuma,1989,DAR,,avermectin,Insecticide,51596-10-2,"(6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-ethylmilbemycin B mixture with (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-methylmilbemycin B",A4: O=C2OC(CC5(OC(CC)C©CC5)O4)CC4C/C=C©/CC©/C=C/C=C(CO3)/C1(O)C3C(O)C©=CC12 A3: O=C2OC(CC5(OC(C)C(C)CC5)O4)CC4C/C=C(C)/CC(C)/C=C/C=C(CO3)/C1(O)C3C(O)C(C)=CC12,rat,65,fc; food concentration,104 weeks,15,0.6999999881,150,6.800000191
+1076,405,Monolinuron,,,UK,1995,"urea, phenyl",herbicide,1746-81-2,N'-(4-chlorophenyl)-N-methoxy-N-methylurea,O=C(N(OC)C)NC1=CC=C(Cl)C=C1,rat,,fc; food concentration,104 weeks,0,0.5,0,2
+2359,406,Myclobutanil,Shellenberger,1986,DAR,2006,triazole,fungicide,88671-89-0,"alpha-butyl-alpha-(4-chlorophenyl)-1H-1,2,4-triazole-1-propanenitrile",CCCCC(C#N)(C2=CC=C(C=C2)Cl)CN1C=NC=N1,rat,54,fc; food concentration,104 weeks,35,2.5,140,9.899999619
+4195,406,Myclobutanil,Wolfe,1993,DAR,2006,triazole,fungicide,88671-89-0,"alpha-butyl-alpha-(4-chlorophenyl)-1H-1,2,4-triazole-1-propanenitrile",CCCCC(C#N)(C2=CC=C(C=C2)Cl)CN1C=NC=N1,rat,60,fc; food concentration,104 weeks,0,0,2500,106
+1078,411,Napropamid,Pettersen,1991,DAR,2006,alkanamide,herbicide,15299-99-7,"N,N-diethyl-2(1-naphthalenyloxy)propanamide",O=C(N(CC)CC)C(OC1=CC=CC2=C1C=CC=C2)C,rat,60,fd; food dose,104 weeks,250,10.47999954,1100,47.56000137
+4199,411,Napropamid,Trutter,1978,DAR,2006,alkanamide,herbicide,15299-99-7,"N,N-diethyl-2(1-naphthalenyloxy)propanamide",O=C(N(CC)CC)C(OC1=CC=CC2=C1C=CC=C2)C,rat,60,fd; food dose,104 weeks,0,30,0,100
+1079,64,Nicosulfuron,Broadmeadow,1991,DAR,2006,"urea, sulfonyl",herbicide,111991-09-4,"2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-N,N-dimethyl-3-pyridinecarboxamide",O=S(C1=C(C(N(C)C)=O)C=CC=N1)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O,rat,60,fc; food concentration,104 weeks,5000,199,50000,2088
+4218,142,Novaluron,Thirlwell,2000,DAR,2008,"urea, benzoyl",insecticide,116714-46-6,"(+-)-N-[[[3-chkloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy]phenyl]amino]carbonyl]-2,6-difluorobenzamide",FC(C=CC=C2F)=C2C(NC(NC1=CC=C(OC(F)(F)C(F)OC(F)(F)F)C(Cl)=C1)=O)=O,rat,72,fc; food concentration,104 weeks,25,1.100000024,700,30.60000038
+4446,439,Orthophenylphenol,Hodge,1952,DAR,2008,others,fungicide,90-43-7,o-hydroxybiphenyl,OC1=C(C2=CC=CC=C2)C=CC=C1,rat,25,fc; food concentration,104 weeks,2000,100,20000,1000
+4447,439,Orthophenylphenol,Washle,1996,DAR,2008,others,fungicide,90-43-7,o-hydroxybiphenyl,OC1=C(C2=CC=CC=C2)C=CC=C1,rat,70,fc; food concentration,104 weeks,800,39,4000,200
+4448,439,Orthophenylphenol,Hiraga,1984,DAR,2008,others,fungicide,90-43-7,o-hydroxybiphenyl,OC1=C(C2=CC=CC=C2)C=CC=C1,rat,20,fc; food concentration,93 weeks,6250,269,12500,531
+6734,1009,Orthosulfamuron,,2004,DAR,2012,"urea, sulfonyl",Herbicide,213464-77-8,"2-[[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]amino]-N,N-dimethylbenzamide",CN(C)C(C(C=CC=C2)=C2NS(NC(NC1=NC(OC)=CC(OC)=N1)=O)(=O)=O)=O,rat,50,fd; food dose,104 weeks,0,5,0,500
+4233,421,Oryzalin,Kitchen,1978,DAR,2009,"2,6-dinitroaniline",herbicide,19044-88-3,"4-(dipropylamino)-3,5-dinitrobenzenesulfonamide",NS(C1=CC([N+]([O-])=O)=C(N(CCC)CCC)C([N+]([O-])=O)=C1)(=O)=O,rat,15,fc; food concentration,52 weeks,0,0,300,14
+4234,421,Oryzalin,Carter,1980,DAR,2009,"2,6-dinitroaniline",herbicide,19044-88-3,"4-(dipropylamino)-3,5-dinitrobenzenesulfonamide",NS(C1=CC([N+]([O-])=O)=C(N(CCC)CCC)C([N+]([O-])=O)=C1)(=O)=O,rat,30,fc; food concentration,104 weeks,300,12,900,36
+6469,983,Oxadiargyl,Aughton,1997,APPLICANT,2012,oxadiazolone,Herbicide,39807-15-3,"3-[2,4-dichloro-5-(2-propynyloxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one",CC(C)(C)C(OC2=O)=NN2C1=CC(OCC#C)=C(Cl)C=C1Cl,rat,50,,104 weeks,0,0,0,0
+1081,999,Oxadiazon,Shirasu,1987,DAR,2007,oxadiazolone,Herbicide,19666-30-9,"3-[2,4-dichloro-5-(1-methylethoxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one",O=C(OC(C(C)(C)C)=N2)N2C1=CC(OC(C)C)=C(Cl)C=C1Cl,rat,80,fc; food concentration,104 weeks,10,0.3600000143,100,3.599999905
+4253,424,Oxamyl,Malley,1991,DAR,2004,"carbamate, oxime",insecticide,23135-22-0,methyl 2-(dimethylamino)-N-[[(methylamino)carbonyl]oxy]-2-oxoethanimidothioate,CNC(ON=C(SC)C(N(C)C)=O)=O,rat,62,fc; food concentration,104 weeks,50,1.970000029,100,4.190000057
+4255,424,Oxamyl,Sherman,1972,DAR,2004,"carbamate, oxime",insecticide,23135-22-0,methyl 2-(dimethylamino)-N-[[(methylamino)carbonyl]oxy]-2-oxoethanimidothioate,CNC(ON=C(SC)C(N(C)C)=O)=O,rat,36,fc; food concentration,104 weeks,50,2.299999952,100,4.900000095
+6116,124,Oxychinolin,NTP,1981,DAR,2011,others,fungicide,148-24-3,8-quinolinol,OC1=C2C(C=CC=N2)=CC=C1,rat,50,fc; food concentration,104 weeks,1500,73,3000,0
+1083,224,Oxydemeton-methyl,Hayes,1984,DAR,2005,organophosphorus,insecticide,301-12-2,"S-[2-(ethylsulfinyl)ethyl] O,O-dimethyl phosphorothioate",O=P(OC)(OC)SCCS(CC)=O,rat,50,fc; food concentration,120 weeks,1,0.02999999933,10,0.2199999988
+1084,425,Oxyfluorfen,Auelleta,1977,DAR,2007,diphenyl ether,herbicide,42874-03-3,2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene,FC(F)(F)C1=CC(Cl)=C(OC2=CC=C([N+]([O-])=O)C(OCC)=C2)C=C1,rat,50,fc; food concentration,104 weeks,40,1.799999952,1109,53
+1085,426,Paclobutrazol,Shaw,1986,DAR,2006,triazole,plant growth regulator,76738-62-0,"(R*,R*)-(+-)-beta-[(4-chlorophenyl)methyl]-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol",CC(C)(C(C(N2C=NC=N2)CC1=CC=C(C=C1)Cl)O)C,rat,60,fc; food concentration,104 weeks,50,2.200000048,250,11
+5044,986,Paraquat,Yoshida,1982,JMPR,2003,quaternary ammonium,Herbicide,4685-14-7,"1,1′-dimethyl-4,4′-bipyridinium",C[N+](C=C2)=CC=C2C1=CC=[N+](C)C=C1,rat,80,fc; food concentration,104 weeks,30,0.7699999809,100,2.549999952
+5045,986,Paraquat,Toyoshima,1982,JMPR,2003,quaternary ammonium,Herbicide,4685-14-7,"1,1′-dimethyl-4,4′-bipyridinium",C[N+](C=C2)=CC=C2C1=CC=[N+](C)C=C1,rat,62,fc; food concentration,104 weeks,100,3,300,8.869999886
+5046,986,Paraquat,Ishmael,1983,JMPR,2003,quaternary ammonium,Herbicide,4685-14-7,"1,1′-dimethyl-4,4′-bipyridinium",C[N+](C=C2)=CC=C2C1=CC=[N+](C)C=C1,rat,70,fc; food concentration,113 weeks,25,1.25,75,3.75
+5454,429,Parathion,Daly,1984,JMPR,1995,organophosphorus,insecticide,56-38-2,"O,O-diethyl O-(4-nitrophenyl) phosphorothioate",CCOP(OC1=CC=C([N+]([!#8])=O)C=C1)(OCC)=S,rat,60,fc; food concentration,120 weeks,5,0.25,50,2.5
+5455,429,Parathion,Eiben,1987,JMPR,1995,organophosphorus,insecticide,56-38-2,"O,O-diethyl O-(4-nitrophenyl) phosphorothioate",CCOP(OC1=CC=C([N+]([!#8])=O)C=C1)(OCC)=S,rat,50,fc; food concentration,52 weeks,8,0.400000006,32,1.600000024
+1086,428,Parathion-methyl,Daly,1983,JMPR,1995,organophosphorus,insecticide,298-00-0,"O,O-dimethyl O-(4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC=C([N+]([O-])=O)C=C1,rat,60,fc; food concentration,104 weeks,5,0.25,50,2.5
+5443,428,Parathion-methyl,Daly,1991,JMPR,1995,organophosphorus,insecticide,298-00-0,"O,O-dimethyl O-(4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC=C([N+]([O-])=O)C=C1,rat,70,fc; food concentration,52 weeks,2.5,0.1099999994,12.5,0.5500000119
+5444,428,Parathion-methyl,Bomhard,1981,JMPR,1995,organophosphorus,insecticide,298-00-0,"O,O-dimethyl O-(4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC=C([N+]([O-])=O)C=C1,rat,50,fc; food concentration,104 weeks,2,0.1000000015,10,0.5
+3304,430,Penconazol,Basler,1985,DAR,2007,triazole,fungicide,66246-88-6,"1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole",CCCC(C2=CC=C(C=C2Cl)Cl)CN1C=NC=N1,rat,80,fc; food concentration,104 weeks,300,15.30000019,0,0
+1088,431,Pencycuron,Shirasu,1981,DAR,2006,"urea, phenyl",fungicide,66063-05-6,N-[(4-chlorophenyl)methyl]-N-cyclopentyl-N'-phenylurea,ClC1=CC=C(CN(C(NC3=CC=CC=C3)=O)C2CCCC2)C=C1,rat,80,fc; food concentration,104 weeks,500,18,5000,180
+6336,2059,Penflufen,Rascle,2009,EU,2011,anilide,Fungicide,494793-67-8,"N-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide",CC(C)CC(C)C1=CC=CC=C1NC(C2=C(F)N(C)N=C2C)=O,rat,80,fc; food concentration,104 weeks,100,4,2000,0
+4484,1608,Penoxsulam,Johnson,2002,DAR,2010,sulfonamide,Herbicide,219714-96-2,"2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide",O=S(NC1=NN2C(C(OC)=CN=C2OC)=N1)(C3=C(OCC(F)F)C=CC=C3C(F)(F)F)=O,rat,65,fd; food dose,104 weeks,0,5,0,50
+6488,1010,Penthiopyrad,Blumbach,2006,DAR,2011,pyrazole,Fungicide,183675-82-3,"N-[2-(1,3-dimethylbutyl)-3-thienyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide",O=C(C2=CN(C)N=C2C(F)(F)F)NC1=C(C(C)CC(C)C)SC=C1,rat,50,fd; food dose,104 weeks,0,27,0,83
+6489,1010,Penthiopyrad,Blumbach,2006,DAR,2011,pyrazole,Fungicide,183675-82-3,"N-[2-(1,3-dimethylbutyl)-3-thienyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide",O=C(C2=CN(C)N=C2C(F)(F)F)NC1=C(C(C)CC(C)C)SC=C1,rat,20,fd; food dose,52 weeks,0,25,0,100
+1089,67,Permethrin,Braun,1977,JMPR,1999,pyrethroid,insecticide,52645-53-1,"(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(C2C(/C=C(Cl)/Cl)C(C)2C)OCC1=CC(OC3=CC=CC=C3)=CC=C1,rat,60,fc; food concentration,104 weeks,100,5,500,25
+5217,67,Permethrin,Richards,1977,JMPR,1999,pyrethroid,insecticide,52645-53-1,"(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(C2C(/C=C(Cl)/Cl)C(C)2C)OCC1=CC(OC3=CC=CC=C3)=CC=C1,rat,60,fc; food concentration,104 weeks,500,25,1000,50
+6131,940,Pethoxamid,Waterson,2000,DAR,2002,amide,Herbicide,106700-29-2,2-chloro-N-(2-ethoxyethyl)-N-(2-methyl-1-phenyl-1-propenyl)acetamide,C/C(C)=C(N(C(CCl)=O)CCOCC)/C1=CC=CC=C1,rat,80,fc; food concentration,104 weeks,25,1,400,17
+5722,2096,Phenothrin,Resnick,1981,JMPR,1988,pyrethroid,Insecticide,26002-80-2,"(3-phenoxyphenyl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate",O=C(C(C(C)3C)C3/C=C(C)/C)OCC1=CC=CC(OC2=CC=CC=C2)=C1,rat,80,fc; food concentration,105 weeks,1000,50,3000,150
+1090,440,Phorat,,,JMPR,2004,organophosphorus,insecticide,298-02-2,"O,O-diethyl S-[(ethylthio)methyl] phosphorodithioate",CCSCSP(OCC)(OCC)=S,rat,50,fc; food concentration,104 weeks,1,0.05000000075,3,0.1599999964
+4290,442,Phosalon,Barker,1993,DAR,2005,organophosphorus,insecticide,2310-17-0,"S-[(6-chloro-2-oxo-3(2H)-benzoxazolyl)methyl] O,O-diethyl phosphorodithioate",CCOP(OCC)(SCN1C(OC2=C1C=CC(Cl)=C2)=O)=S,rat,50,fc; food concentration,104 weeks,50,1.799999952,500,23.39999962
+4303,443,Phosmet,Johnston,1966,DAR,2005,organophosphorus,insecticide,732-11-6,"S-[(1,3-dihydro1,3-dioxo-2H-isoindol-2-yl)methyl] O,O-dimethyl phosphorodithioate",S=P(OC)(OC)SCN1C(C(C=CC=C2)=C2C1=O)=O,rat,25,fc; food concentration,104 weeks,0,0,40,4
+4304,443,Phosmet,Chang,1988,DAR,2005,organophosphorus,insecticide,732-11-6,"S-[(1,3-dihydro1,3-dioxo-2H-isoindol-2-yl)methyl] O,O-dimethyl phosphorodithioate",S=P(OC)(OC)SCN1C(C(C=CC=C2)=C2C1=O)=O,rat,60,fc; food concentration,104 weeks,20,1.100000024,40,1.799999952
+5747,444,Phosphamidon,Mayhew,1986,JMPR,1986,organophosphorus,insecticide,13171-21-6,2-chloro-3-(diethylamino)-1-methyl-3-oxo-1-propenyl dimethyl phosphate,CCN(C(/C(Cl)=C(OP(OC)(OC)=O)/C)=O)CC,rat,60,fc; food concentration,104 weeks,1,0,30,0
+1093,1032,Picloram,Landry,1986,DAR,2007,pyridine,Herbicide,1918-02-1,"4-amino-3,5,6-trichloro-2-pyridinecarboxylic acid",O=C(O)C1=NC(Cl)=C(Cl)C(N)=C1Cl,rat,60,fd; food dose,104 weeks,0,60,0,200
+4309,1032,Picloram,Cosse,1992,DAR,2007,pyridine,Herbicide,1918-02-1,"4-amino-3,5,6-trichloro-2-pyridinecarboxylic acid",O=C(O)C1=NC(Cl)=C(Cl)C(N)=C1Cl,rat,50,fd; food dose,104 weeks,0,0,0,250
+6547,981,Picolinafen,Kelly,1999,DAR,2000,anilide,Herbicide,137641-05-5,N-(4-fluorophenyl)-6-[3-(trifluoromethyl)phenoxy]-2-pyridinecarboxamide,FC(F)(F)C1=CC(OC2=CC=CC(C(NC3=CC=C(F)C=C3)=O)=N2)=CC=C1,rat,65,fc; food concentration,104 weeks,50,2.400000095,250,12.10000038
+6078,317,Picoxystrobin,Rattray,1999,JMPR,2012,strobilurin,fungicide,117428-22-5,methyl (αE)-α-(methoxymethylene)-2-[[[6-(trifluoromethyl)-2-pyridinyl]oxy]methyl]benzeneacetate,FC(F)(F)C1=CC=CC(OCC2=C(/C(C(OC)=O)=C\OC)C=CC=C2)=N1,rat,64,fc; food concentration,104 weeks,200,12,750,46
+7016,317,Picoxystrobin,Craig,2011,JMPR,2012,strobilurin,fungicide,117428-22-5,methyl (αE)-α-(methoxymethylene)-2-[[[6-(trifluoromethyl)-2-pyridinyl]oxy]methyl]benzeneacetate,FC(F)(F)C1=CC=CC(OCC2=C(/C(C(OC)=O)=C\OC)C=CC=C2)=N1,rat,80,fc; food concentration,104 weeks,1000,45,3500,162
+1094,933,Pinoxaden,Bachmann,2003,DAR,2006,others,Herbicide,243973-20-8,"8-(2,6-diethyl-4-methylphenyl)-1,2,4,5-tetrahydro-7-oxo-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl 2,2-dimethylpropanoate",CCC1=C(C2=C(OC(C(C)(C)C)=O)N(CCOCC3)N3C2=O)C(CC)=CC(C)=C1,rat,90,gc; gavage concentration,104 weeks,0,10,0,100
+1095,447,Piperonylbutoxid,Graham,1987,JMPR,1995,others,insecticide,51-03-6,"5-((2-(2-butoxyethoxy)ethoxy)methyl)-6-propyl-1,3-benzodioxole",CCCCOCCOCCOCC1=C(CCC)C=C(OCO2)C2=C1,rat,60,fd; food dose,104 weeks,0,30,0,100
+4328,448,Pirimicarb,Tinston,1992,DAR,2004,carbamate,insecticide,23103-98-2,"2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl dimethylcarbamate",CN(C)C1=NC(C)=C(C)C(OC(N(C)C)=O)=N1,rat,64,fc; food concentration,104 weeks,75,3.700000048,250,12.30000019
+1097,450,Pirimiphos-methyl,Gore,1974,DAR,2005,organophosphorus,insecticide,29232-93-7,"O-[2-(diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl phosphorothioate",S=P(OC)(OC)OC1=NC(N(CC)CC)=NC(C)=C1,rat,40,fc; food concentration,104 weeks,10,0.400000006,50,2.099999905
+1098,2048,Prallethrin,,,UK,1995,pyrethroid,Insecticide,23031-36-9,"2-methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate",O=C(C2C(/C=C(C)/C)C(C)2C)OC1CC(C(CC#C)=C1C)=O,rat,,fc; food concentration,104 weeks,0,3.269999981,0,16.5
+4348,453,Prochloraz,Colley,1982,DAR,2007,imidazole,fungicide,67747-09-5,"N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide",CCCN(C(N2C=CN=C2)=O)CCOC1=C(Cl)C=C(Cl)C=C1Cl,rat,60,fc; food concentration,104 weeks,150,5,625,21.5
+1100,455,Procymidon,Keller,1986,JMPR,2007,dicarboximide,fungicide,32809-16-8,"3-(3,5-dichlorophenyl)-1,5-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione",CC12CC(C(N(C3=CC(Cl)=CC(Cl)=C3)C2=O)=O)1C,rat,50,fc; food concentration,104 weeks,300,14,1000,48
+1101,456,Profenofos,Burdock,1981,JMPR,2007,organophosphorus,insecticide,41198-08-7,O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate,O=P(OCC)(SCCC)OC1=C(Cl)C=C(Br)C=C1,rat,60,fc; food concentration,104 weeks,100,5.699999809,0,0
+4361,313,Prohexadione,Inoue,1993,DAR,2009,others,plant growth regulator,127277-53-6,"calcium 3,5-dioxo-4-(1-oxopropyl)cyclohexanecarboxylate",O=C([O-])C(CC([O-])=C1C(CC)=O)CC1=O.[Ca+2],rat,80,fc; food concentration,104 weeks,2000,93.90000153,10000,469
+1102,460,Propamocarb,McFarlane,1998,DAR,2005,carbamate,fungicide,24579-73-5,propyl [3-(dimethylamino)propyl]carbamate,O=C(OCCC)NCCCN(C)C.[H]Cl,rat,70,fc; food concentration,104 weeks,2800,84,22400,682
+4377,460,Propamocarb,Hunter,1983,DAR,2005,carbamate,fungicide,24579-73-5,propyl [3-(dimethylamino)propyl]carbamate,O=C(OCCC)NCCCN(C)C.[H]Cl,rat,50,fc; food concentration,104 weeks,1000,25.60000038,0,0
+4378,460,Propamocarb,Blair,2001,DAR,2005,carbamate,fungicide,24579-73-5,propyl [3-(dimethylamino)propyl]carbamate,O=C(OCCC)NCCCN(C)C.[H]Cl,rat,70,fc; food concentration,104 weeks,0,0,2000,150
+4379,460,Propamocarb,Schoenmakers,2002,DAR,2005,carbamate,fungicide,24579-73-5,propyl [3-(dimethylamino)propyl]carbamate,O=C(OCCC)NCCCN(C)C.[H]Cl,rat,20,fc; food concentration,52 weeks,375,29,1500,114
+4127,1609,Propanil,Bellinger,1994,DAR,2008,anilide,Herbicide,709-98-8,"N-(3,4-dichlorophenyl)propanamide",O=C(CC)NC1=CC(Cl)=C(Cl)C=C1,rat,70,fc; food concentration,104 weeks,0,0,200,9
+1103,461,Propaquizafop,Buser,1989,DAR,2006,2-(4aryloxyphenoxy)propionic acid,herbicide,111479-05-1,(R)-2-[[(1-methylethylidene)amino]oxy]ethyl 2-[4-[(6-chloro-2-quinoxalinyloxy]-phenoxy]propanoate,ClC1=CC=C2C(N=CC(OC3=CC=C(OC(C)C(OCCO/N=C(C)/C)=O)C=C3)=N2)=C1,rat,70,fd; food dose,104 weeks,0,1.5,0,5
+4118,461,Propaquizafop,Buser,1991,DAR,2006,2-(4aryloxyphenoxy)propionic acid,herbicide,111479-05-1,(R)-2-[[(1-methylethylidene)amino]oxy]ethyl 2-[4-[(6-chloro-2-quinoxalinyloxy]-phenoxy]propanoate,ClC1=CC=C2C(N=CC(OC3=CC=C(OC(C)C(OCCO/N=C(C)/C)=O)C=C3)=N2)=C1,rat,50,fd; food dose,104 weeks,0,5,0,25
+1104,462,Propargit,Ober,1966,DAR,2007,others,acaricide,2312-35-8,"2-[4(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl sulfite",CC(C)(C2=CC=C(C=C2)OC1CCCCC1OS(OCC#C)=O)C,rat,25,fd; food dose,104 weeks,0,5,0,15
+4108,462,Propargit,Trutter,1991,DAR,2007,others,acaricide,2312-35-8,"2-[4(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl sulfite",CC(C)(C2=CC=C(C=C2)OC1CCCCC1OS(OCC#C)=O)C,rat,60,fc; food concentration,104 weeks,80,3.460000038,400,24.20000076
+4109,462,Propargit,Goldenthal,1993,DAR,2007,others,acaricide,2312-35-8,"2-[4(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl sulfite",CC(C)(C2=CC=C(C=C2)OC1CCCCC1OS(OCC#C)=O)C,rat,60,fc; food concentration,104 weeks,0,0,0,0
+4110,462,Propargit,Goldenthal,1998,DAR,2007,others,acaricide,2312-35-8,"2-[4(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl sulfite",CC(C)(C2=CC=C(C=C2)OC1CCCCC1OS(OCC#C)=O)C,rat,55,fc; food concentration,87 weeks,80,3.730000019,400,25.20000076
+4759,2167,Propazin,,,USA,1998,triazine,Herbicide,139-40-2,"6-chloro-N,N′-bis(1-methylethyl)-1,3,5-triazine-2,4-diamine",,rat,60,fc; food concentration,104 weeks,100,5.199999809,1000,51
+5585,3,Propham,Eiben,1988,JMPR,1992,"carbamate, phenyl",herbicide,122-42-9,1-methylethyl phenylcarbamate,O=C(OC(C)C)NC1=CC=CC=C1,rat,20,fc; food concentration,52 weeks,100,5.800000191,0,0
+5586,3,Propham,Eiben,1989,JMPR,1992,"carbamate, phenyl",herbicide,122-42-9,1-methylethyl phenylcarbamate,O=C(OC(C)C)NC1=CC=CC=C1,rat,20,fc; food concentration,104 weeks,100,5.699999809,500,29
+1105,454,Propiconazol,Hunter,1985,JMPR,2004,triazole,fungicide,60207-90-1,"1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole",CCCC1COC(C2=CC=C(Cl)C=C2Cl)(CN3N=CN=C3)O1,rat,70,fc; food concentration,104 weeks,500,18,2500,96
+1106,61,Propineb,Loser,1974,JMPR,1993,dithiocarbamate,fungicide,12071-83-9,"[[(1-methyl-1,2-ethanediyl)bis[carbamodithioato]](2-)]zinc homopolymer",[S]C(NC(C)CNC(S[Zn])=S)=S,rat,40,fc; food concentration,104 weeks,50,2.5,100,5
+5495,61,Propineb,Loser,1974,JMPR,1993,dithiocarbamate,fungicide,12071-83-9,"[[(1-methyl-1,2-ethanediyl)bis[carbamodithioato]](2-)]zinc homopolymer",[S]C(NC(C)CNC(S[Zn])=S)=S,rat,25,fc; food concentration,104 weeks,10,0.5,100,5
+4389,2032,Propisochlor,Korom,1995,DAR,2009,chloroacetanilide,Herbicide,86763-47-5,2-chloro-N-(2-ethyl-6-methylphenyl)-N-[(1-methylethoxy)methyl]acetamide,O=C(N(C1=C(C)C=CC=C1CC)COC(C)C)CCl,rat,40,fd; food dose,52 weeks,0,63,0,200
+4390,2032,Propisochlor,Korom,1995,DAR,2009,chloroacetanilide,Herbicide,86763-47-5,2-chloro-N-(2-ethyl-6-methylphenyl)-N-[(1-methylethoxy)methyl]acetamide,O=C(N(C1=C(C)C=CC=C1CC)COC(C)C)CCl,rat,60,fd; food dose,104 weeks,0,20,0,63
+5686,4,Propoxur,Jurek,1978,JMPR,1989,carbamate,insecticide,114-26-1,2-(1-methylethoxy)phenyl methylcarbamate,O=C(NC)OC(C=CC=C1)=C1OC(C)C,rat,20,fc; food concentration,78 weeks,200,0,800,0
+5687,4,Propoxur,,,JMPR,1989,carbamate,insecticide,114-26-1,2-(1-methylethoxy)phenyl methylcarbamate,O=C(NC)OC(C=CC=C1)=C1OC(C)C,rat,50,fc; food concentration,104 weeks,200,9.600000381,1000,48
+6508,315,Propoxycarbazon-Natrium,Wahle,1999,DAR,2001,"urea, triazinylsulfonyl",herbicide,181274-15-7,"sodium, methyl 2-[[[(4,5-dihydro-4-methyl-5-oxo-3-propoxy-1H-1,2,4-triazol-1-yl)carbonyl]amino]sulfonyl]benzoate",O=S(C1=C(C(OC)=O)C=CC=C1)([N-]C(N2N=C(OCCC)N(C)C2=O)=O)=O.[Na+],rat,50,fd; food dose,104 weeks,0,43,0,500
+5486,1610,Propylenethiourea,Weber,1979,JMPR,1993,,,,,,rat,40,fc; food concentration,104 weeks,10,0.5,100,5
+5489,1610,Propylenethiourea,Bomhard,1980,JMPR,1993,,,,,,rat,50,fc; food concentration,104 weeks,10,0.5600000024,100,5.599999905
+1107,5,Propyzamid,,,UK,1996,carboxamide,herbicide,23950-58-5,"3,5-dichloro-N-(1,1-dimethyl-2-propynyl)benzamide",O=C(NC(C)(C)C#C)C1=CC(Cl)=CC(Cl)=C1,rat,,fc; food concentration,104 weeks,0,8.460000038,0,42.5
+1108,939,Proquinazid,Malley,2002,DAR,2006,,Fungicide,189278-12-4,6-iodo-2-propoxy-3-propyl-4(3H)-quinazolinone,IC1=CC=C(N=C(OCCC)N(CCC)C2=O)C2=C1,rat,80,fc; food concentration,104 weeks,30,1.200000048,300,12
+1109,6,Prosulfocarb,Pettersen,1988,DAR,2005,thiocarbamate,herbicide,52888-80-9,S-(phenylmethyl) dipropylcarbamothioate,O=C(SCC1=CC=CC=C1)N(CCC)CCC,rat,60,fc; food concentration,104 weeks,10,0.5,45,2.299999952
+6983,115,Prosulfuron,,,DAR,2013,"urea, triazinylsulfonyl",herbicide,94125-34-5,"N-[[3.(4.methoxy-6-methyl-1,3,5-triazin-2-yl)-amino]carbonyl]-2-(3,3,3-trifluoropropyl)benzene sulfonamide",O=S(C1=C(CCC(F)(F)F)C=CC=C1)(NC(NC2=NC(C)=NC(OC)=N2)=O)=O,rat,,fc; food concentration,104 weeks,0,8.600000381,0,88
+1110,329,Prothioconazol,Wirnitzer,2001,DAR,2004,triazole,fungicide,178928-70-6,"2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione",ClC1=C(CC(C3(CC3)Cl)(O)CN2N=CNC2=S)C=CC=C1,rat,50,gc; gavage concentration,104 weeks,0,5,0,50
+3977,329,Prothioconazol,Wirnitzer,2000,DAR,2004,triazole,fungicide,178928-70-6,"2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione",ClC1=C(CC(C3(CC3)Cl)(O)CN2N=CNC2=S)C=CC=C1,rat,20,gc; gavage concentration,52 weeks,0,50,0,750
+3995,2155,"Prothioconazol, desthio",Wirnitzer,2000,DAR,2004,,,,,,rat,60,fc; food concentration,104 weeks,20,1.100000024,140,8
+1111,121,Pymetrozin,,1995,DAR,2013,"1,2,4-triazinone",insecticide,123312-89-0,"(E)-4,5-dihydro-6-methyl-4-[(3-pyridinylmethylene)amino]-1,2,4-triazin-3(2H)-one",O=C1N(/N=C/C2=CC=CN=C2)CC(C)=NN1,rat,80,fc; food concentration,104 weeks,100,3.75999999,1000,39.29999924
+6536,318,Pyraclostrobin,Mellert,1990,DAR,2003,strobilurin,fungicide,175013-18-0,"carbamic acid, [2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]methoxy-, methyl ester",CON(C(OC)=O)C(C=CC=C3)=C3COC2=NN(C=C2)C1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,75,3.400000095,200,9
+1113,1012,Pyrasulfotol,,,USA,2007,pyrazole,Herbicide,365400-11-9,"(5-hydroxy-1,3-dimethyl-1H-pyrazol-4-yl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone",CS(C1=CC(C(F)(F)F)=CC=C1C(C2=C(O)N(C)N=C2C)=O)(=O)=O,rat,,fc; food concentration,104 weeks,25,1,250,10
+5573,8,Pyrazophos,Otaka,1983,JMPR,1992,organophosphorus,fungicide,13457-18-6,"ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate",O=C(C(C(C)=N2)=CN1C2=CC(OP(OCC)(OCC)=S)=N1)OCC,rat,40,fc; food concentration,52 weeks,20,1,200,11
+5578,8,Pyrazophos,Til,1979,JMPR,1992,organophosphorus,fungicide,13457-18-6,"ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate",O=C(C(C(C)=N2)=CN1C2=CC(OP(OCC)(OCC)=S)=N1)OCC,rat,30,fc; food concentration,104 weeks,50,2.5,0,0
+5579,8,Pyrazophos,Tennekes,1991,JMPR,1992,organophosphorus,fungicide,13457-18-6,"ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate",O=C(C(C(C)=N2)=CN1C2=CC(OP(OCC)(OCC)=S)=N1)OCC,rat,50,fc; food concentration,117 weeks,2,0.1000000015,80,4
+3955,10,Pyrethrine,Goldenthal,1990,DAR,2007,pyrethrin,insecticide,8003-34-7,Pyrethrins,,rat,60,fc; food concentration,104 weeks,100,4.400000095,1000,43
+1114,106,Pyridaben,Holmes,1990,DAR,2007,pyridazinone,insecticide,96489-71-3,"4-chloro-2-(1,1-dimethylethyl)-5-[[[4-(1,1-dimethylethyl)phenyl]methyl]thio]-3(2H)-pyridazinone",CC(C)(C)C1=CC=C(CSC2=C(Cl)C(N(C(C)(C)C)N=C2)=O)C=C1,rat,85,fc; food concentration,104 weeks,28,1.129999995,80,5
+1115,2043,Pyridalyl,,,USA,2008,others,Insecticide,179101-81-6,"2-[3-[2,6-dichloro-4-[(3,3-dichloro-2-propenyl)oxy]phenoxy]propoxy]-5-(trifluoromethyl)pyridine",FC(F)(F)C1=CC=C(OCCCOC2=C(Cl)C=C(OC/C=C(Cl)\Cl)C=C2Cl)N=C1,rat,,fc; food concentration,104 weeks,0,3.400000095,0,17.10000038
+6969,11,Pyridate,Anonymous,,DAR,2013,others,herbicide,55512-33-9,O-(6-chloro-3-phenyl-4-pyridazinyl) S-octyl carbonothioate,CCCCCCCCSC(OC1=C(C2=CC=CC=C2)N=NC(Cl)=C1)=O,rat,75,fd; food dose,104 weeks,0,18,0,115
+3862,143,Pyrimethanil,Rees,1993,DAR,2004,"pyrimidine, anilino",fungicide,53112-28-0,"4,6-dimethyl-N-phenyl-2-pyrimidinamine",CC1=NC(NC2=CC=CC=C2)=NC(C)=C1,rat,70,fc; food concentration,104 weeks,400,17,5000,221
+6455,2152,Pyriofenon,Anonymous,2010,DAR,2012,,Fungicide,688046-61-9,"(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)methanone",,rat,20,fc; food concentration,52 weeks,200,8.510000229,1000,42.90000153
+6456,2152,Pyriofenon,Anonymous,2010,DAR,2012,,Fungicide,688046-61-9,"(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)methanone",,rat,50,fc; food concentration,104 weeks,200,7.25,1000,36.40000153
+1117,107,Pyriproxyfen,Osheroff,1991,DAR,2005,diphenyl ether,insecticide,95737-68-1,2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine,CC(COC2=CC=C(OC3=CC=CC=C3)C=C2)OC1=CC=CC=N1,rat,80,fc; food concentration,104 weeks,600,27.20000076,3000,138.6999969
+6586,993,Pyroxsulam,Stebbins,2008,DAR,2012,sulfonamide,Herbicide,422556-08-9,"N-(5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)-3-pyridinesulfonamide",O=S(NC1=NN2C(N=C(OC)C=C2OC)=N1)(C3=C(OC)N=CC=C3C(F)(F)F)=O,rat,65,fd; food dose,104 weeks,0,100,0,1000
+1119,1045,Quinmerac,Schilling,1990,DAR,2007,"quinoline, carboxylic acid",Herbicide,90717-03-6,7-chloro-3-methyl-8-quinolinecarboxylic acid,ClC1=CC=C(C=C(C)C=N2)C2=C1C(O)=O,rat,50,fc; food concentration,104 weeks,6000,317,0,0
+3454,1045,Quinmerac,Schilling,1990,DAR,2007,"quinoline, carboxylic acid",Herbicide,90717-03-6,7-chloro-3-methyl-8-quinolinecarboxylic acid,ClC1=CC=C(C=C(C)C=N2)C2=C1C(O)=O,rat,25,fc; food concentration,52 weeks,6000,364,12000,740
+1120,973,Quinoclamine,Husband,1991,DAR,2006,quinone,Algicide,2797-51-5,"2-amino-3-chloro-1,4-naphthalenedione",O=C2C(N)=C(Cl)C(C1=CC=CC=C12)=O,rat,50,fc; food concentration,104 weeks,4,0.2099999934,52,2.890000105
+1121,334,Quinoxyfen,Redmond,1995,JMPR,2006,"quinoline, phenoxy",fungicide,124495-18-7,"5,7-dichloro-4-(4-fluorophenoxy)quinoline",FC(C=C3)=CC=C3OC1=CC=NC2=C1C(Cl)=CC(Cl)=C2,rat,50,fd; food dose,104 weeks,0,20,0,80
+1122,14,Quintozen,Goldenthal,1991,JMPR,1995,"benzene, nitro",fungicide,82-68-8,pentachloronitrobenzene,[O-][N+](C(C(Cl)=C(Cl)C(Cl)=C1Cl)=C1Cl)=O,rat,50,fc; food concentration,104 weeks,20,0.8999999762,3000,141
+1123,15,Quizalofop-ethyl,Barnard,1985,DAR,2007,"propionic acid, aryloxyphenoxy",herbicide,76578-14-8,"2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propionsäure, ethylester",CCOC(C(OC3=CC=C(C=C3)OC2=NC1=CC=C(Cl)C=C1N=C2)C)=O,rat,50,fc; food concentration,104 weeks,25,0.8999999762,100,15.5
+3433,2153,Quizalofop-P-tefuryl,Goldenthal,1994,DAR,2007,"(4-aryloxyphenoxy)propionic acid, 2-",Herbicide,119738-06-6,(tetrahydro-2-furanyl)methyl (2R)-2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propanoate,,rat,65,fc; food concentration,104 weeks,25,1.299999952,750,39.5
+1124,114,Rimsulfuron,Keller,1991,DAR,2003,"urea, sulfonyl",herbicide,122931-48-0,"N-[[4,6-dimethoxy-2-pyrimidyl)amino]carbonyl]-3-(etylsulfonyl)-2-pyridinesulfonamide",O=S(C1=C(S(CC)(=O)=O)C=CC=N1)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O,rat,62,fc; food concentration,104 weeks,300,11.80000019,3000,121
+4742,2023,Saflufenacil,Kaspers,2007,JMPR,2011,uracil,Herbicide,372137-35-4,"2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]benzamide",O=C(NS(N(C(C)C)C)(=O)=O)C1=CC(N2C(C=C(C(F)(F)F)N(C)C2=O)=O)=C(F)C=C1Cl,rat,50,fc; food concentration,104 weeks,100,6.199999809,500,31.39999962
+6259,2017,Sedaxan,Perry,2010,DAR,2011,pyrazole,Fungicide,874967-67-6,"N-[2-[1,1′-bicyclopropyl]-2-ylphenyl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide",O=C(C2=CN(C)N=C2C(F)F)NC1=C(C3CC3C4CC4)C=CC=C1,rat,64,fc; food concentration,104 weeks,200,11,1200,67
+3396,2091,Sintofen,Richard,1996,DAR,2007,others,Plant growth regulator,130561-48-7,"1-(4-chlorophenyl)-1,4-dihydro-5-(2-methoxyethoxy)-4-oxo-3-cinnolinecarboxylic acid",,rat,80,fc; food concentration,104 weeks,300,12.60000038,1700,0
+6644,1029,Spinetoram,Yano,2007,DAR,2012,spinosyn,Insecticide,187166-40-1,"(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-α-L-mannopyranosyl)oxy]-13-[[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2,3,3a,4,5,5a,5b,6,9,10,11,12,13,14,16a,16b-hexadecahydro-14-methyl-1H-as-i",C[C@H]([C@@H](N(C)C)CC5)O[C@H]5O[C@@H]2[C@@H](C)C(C1=C[C@]3([H])[C@](CC[C@@]4([H])[C@]([H])3C[C@H](O[C@@H]6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C4)([H])[C@@]([H])1CC(O[C@@H](CC)CCC2)=O)=O,rat,65,fc; food concentration,104 weeks,250,10.80000019,500,21.60000038
+1125,357,Spinosad,Bond,1995,JMPR,2001,others,insecticide,168316-95-8,"(2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-2-[(6-deoxy-2,3,4-tri-O-methyl-α-L-mannopyranosyl)oxy]-13-[[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-14-methyl-1H-as-indaceno[3,",Spinosyn D: O=C2C(C)C(OC1CCC(N(C)C)C(C)O1)CCCC(CC)OC(CC3C2=CC4C3C=C(C)C5C4CC(OC6C(OC)C(OC)C(OC)C(C)O6)C5)=O Spinosyn A: O=C2C(C)C(OC1CCC(N(C)C)C(C)O1)CCCC(CC)OC(CC3C2=CC4C3C=CC5C4CC(OC6C(OC)C(OC)C(OC)C(C)O6)C5)=O,rat,65,fc; food concentration,104 weeks,50,2.400000095,200,9.5
+1126,320,Spirodiclofen,Wimitzer,2000,DAR,2004,tetronic acid,acaricide,148477-71-8,"Butonic acid, 2,2-dimethyl-,3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5] dec-3-en-4-yl ester",O=C1OC3(CCCCC3)C(OC(C(C)(C)CC)=O)=C1C2=C(Cl)C=C(Cl)C=C2,rat,50,fc; food concentration,108 weeks,100,4.110000134,350,14.72000027
+3356,1021,Spiromesifen,Schladt,2001,DAR,2004,tetronic acid,Insecticide,283594-90-1,"2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate",CC1=CC(C)=CC(C)=C1C2=C(OC(CC(C)(C)C)=O)C3(CCCC3)OC2=O,rat,25,fc; food concentration,52 weeks,125,6.5,300,15.89999962
+3357,1021,Spiromesifen,Schladt,2001,DAR,2004,tetronic acid,Insecticide,283594-90-1,"2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate",CC1=CC(C)=CC(C)=C1C2=C(OC(CC(C)(C)C)=O)C3(CCCC3)OC2=O,rat,50,fc; food concentration,104 weeks,125,6.099999905,300,14.80000019
+3308,994,Spirotetramat,Wahle,2005,DAR,2008,tetramic acid,Insecticide,203313-25-1,"cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate",CC1=CC=C(C)C=C1C(C(N3)=O)=C(OC(OCC)=O)C23CCC(OC)CC2,rat,25,fc; food concentration,52 weeks,250,13.19999981,3500,189
+3309,994,Spirotetramat,Wahle,2006,DAR,2008,tetramic acid,Insecticide,203313-25-1,"cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate",CC1=CC=C(C)C=C1C(C(N3)=O)=C(OC(OCC)=O)C23CCC(OC)CC2,rat,55,fc; food concentration,104 weeks,250,13.19999981,3500,189
+3271,345,Spiroxamine,Eiben,1994,DAR,2009,others,fungicide,118134-30-8,"8-(1,1-dimethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro[4.5]decane -2-methanamine",CC(C)(C)C1CCC2(OC(CN(CCC)CC)CO2)CC1,rat,50,fc; food concentration,104 weeks,70,4.21999979,490,32.81000137
+1130,161,Sulcotrione,Pavkov,1990,DAR,2006,triketone,herbicide,99105-77-8,"2-[2-chloro-4-(metylsulfonyl)benzoyl]-1,3-cyclohexandione",CS(C(C=C2Cl)=CC=C2C(C(C(CCC1)=O)C1=O)=O)(=O)=O,rat,60,fc; food concentration,104 weeks,50,2,1900,72
+3255,161,Sulcotrione,Potrepka,1991,DAR,2006,triketone,herbicide,99105-77-8,"2-[2-chloro-4-(metylsulfonyl)benzoyl]-1,3-cyclohexandione",CS(C(C=C2Cl)=CC=C2C(C(C(CCC1)=O)C1=O)=O)(=O)=O,rat,50,fc; food concentration,104 weeks,1,0.03999999911,10,0.400000006
+1131,2044,Sulfentrazon,,,USA,1997,anilide,Herbicide,122836-35-5,"N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide",CS(NC1=C(Cl)C=C(Cl)C(N2C(N(C(F)F)C(C)=N2)=O)=C1)(=O)=O,rat,60,fc; food concentration,104 weeks,600,36.40000153,1000,67
+6955,170,Sulfosulfuron,Naylor,1997,DAR,2013,"urea, sulfonyl",herbicide,141776-32-1,"N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide",O=S(C1=C(S(CC)(=O)=O)N=C2N1C=CC=C2)(NC(NC3=NC(OC)=CC(OC)=N3)=O)=O,rat,,fc; food concentration,104 weeks,500,24.39999962,5000,1296.5
+6408,2018,Sulfoxaflor,Stebbins,2010,DAR,2012,others,Insecticide,946578-00-3,N-[methyloxido[1-[6-(trifluoromethyl)-3-pyridinyl]ethyl]-λ4-sulfanylidene]cyanamide,FC(F)(F)C1=CC=C(C(S(C)(=O)=NC#N)C)C=N1,rat,60,fc; food concentration,104 weeks,25,1.039999962,100,4.239999771
+3245,336,tau-Fluvalinat,Goldenthal,1984,DAR,2009,pyrethroid,insecticide,102851-06-9,cyano(3-phenoxyphenyl)methyl N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valinate,FC(F)(F)C1=CC=C(N[C@@H]([C@H](C)C)C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O)C(Cl)=C1,rat,85,gd; gavage dose,104 weeks,0,0.5,0,1
+3228,23,Tebuconazol,Bomhard,1988,DAR,2006,triazole,fungicide,107534-96-3,"(+-)-alpha-[2-(4-chlorophenyl)ethyl]-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol",CC(C)(C(CCC1=CC=C(Cl)C=C1)(CN2C=NC=N2)O)C,rat,60,fc; food concentration,104 weeks,300,15.89999962,1000,55
+3216,117,Tebufenozid,Trutter,1992,DAR,2005,carboxamide,insecticide,112410-23-8,"3,5-diemthylbenzoic acid 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide",O=C(NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O)C1=CC=C(C=C1)CC,rat,70,fc; food concentration,104 weeks,100,4.800000191,1000,48.40000153
+1135,69,Tebufenpyrad,Mitchell,1992,DAR,2007,carboxamide,acaricide,119168-77-3,"4-chloro-N[[4-(1,1-dimethylethyl)phenyl]methyl]-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide",CN1N=C(C(Cl)=C1C(NCC2=CC=C(C=C2)C(C)(C)C)=O)CC,rat,65,fc; food concentration,104 weeks,20,0.8000000119,150,6.5
+5469,25,Tecnazen,Ben-Dyke,1978,JMPR,1994,"benzene, nitro",fungicide,117-18-0,"1,2,4,5-tetrachloro-3-nitrobenzene",ClC1=C(Cl)C=C(Cl)C(Cl)=C1[N+]([O-])=O,rat,65,fc; food concentration,104 weeks,1500,56,0,0
+3111,26,Teflubenzuron,Suter,1987,DAR,2007,"urea, benzoyl",insecticide,83121-18-0,"N-[[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl]-2,6-difluorobenzamide",FC1=CC=CC(F)=C1C(NC(NC2=CC(Cl)=C(C(Cl)=C2F)F)=O)=O,rat,70,fc; food concentration,120 weeks,100,4.800000191,500,24.79999924
+3112,26,Teflubenzuron,Tennekes,1989,DAR,2007,"urea, benzoyl",insecticide,83121-18-0,"N-[[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl]-2,6-difluorobenzamide",FC1=CC=CC(F)=C1C(NC(NC2=CC(Cl)=C(C(Cl)=C2F)F)=O)=O,rat,60,fc; food concentration,104 weeks,0,0,2500,122.5
+1138,1027,Tefluthrin,Stonard,1986,DAR,2006,pyrethroid,Insecticide,79538-32-2,"(2,3,5,6-tetrafluoro-4-methylphenyl)methyl (1R,3R)-rel-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]-2,2-dimethylcyclopropanecarboxylate",FC(F)(F)/C(Cl)=C/C1C(C)(C)C1C(OCC2=C(F)C(F)=C(C)C(F)=C2F)=O,rat,76,fc; food concentration,104 weeks,25,1.5,100,5.900000095
+1139,950,Tembotrion,Kennel,2005,DAR,2008,triketone,Herbicide,335104-84-2,"2-[2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoyl]-1,3-cyclohexanedione",O=C(CCC1)C(C(C2=CC=C(S(=O)(C)=O)C(COCC(F)(F)F)=C2Cl)=O)C1=O,rat,75,fc; food concentration,104 weeks,2,0.03999999911,20,1.049999952
+4877,2169,Temephos,Tegeris,1977,JMPR,2006,organophosphorus,Insect attractant,3383-96-8,"O,O′-(thiodi-4,1-phenylene) bis(O,O-dimethyl phosphorothioate)",,rat,60,fc; food concentration,104 weeks,300,15,0,0
+5067,28,Terbufos,Daly,1987,JMPR,2003,organophosphorus,insecticide,13071-79-9,"S-[[(1,1-dimethylethyl)thio]methyl] O,O-diethyl phosphorodithioate",S=P(OCC)(OCC)SCSC(C)(C)C,rat,30,fc; food concentration,52 weeks,1,0.0549999997,0,0
+5071,28,Terbufos,Rapp,1974,JMPR,2003,organophosphorus,insecticide,13071-79-9,"S-[[(1,1-dimethylethyl)thio]methyl] O,O-diethyl phosphorodithioate",S=P(OCC)(OCC)SCSC(C)(C)C,rat,60,fc; food concentration,104 weeks,1,0.05000000075,2,0.1000000015
+3044,30,Terbuthylazin,Gfeller,1983,DAR,2007,triazine,herbicide,5915-41-3,"6-chloro-N-(1,1-dimethylethyl)-N'-ethyl-1,3,5-triazine-2,4-diamine",ClC1=NC(NCC)=NC(NC(C)(C)C)=N1,rat,80,fc; food concentration,104 weeks,0,0,30,1.24000001
+3045,30,Terbuthylazin,Gfeller,1983,DAR,2007,triazine,herbicide,5915-41-3,"6-chloro-N-(1,1-dimethylethyl)-N'-ethyl-1,3,5-triazine-2,4-diamine",ClC1=NC(NCC)=NC(NC(C)(C)C)=N1,rat,80,fc; food concentration,104 weeks,6,0.349999994,30,1.590000033
+3046,30,Terbuthylazin,Ramesh,2001,DAR,2007,triazine,herbicide,5915-41-3,"6-chloro-N-(1,1-dimethylethyl)-N'-ethyl-1,3,5-triazine-2,4-diamine",ClC1=NC(NCC)=NC(NC(C)(C)C)=N1,rat,50,fc; food concentration,104 weeks,10,0.400000006,40,1.700000048
+1140,109,Tetraconazol,Crome,1992,DAR,2005,triazole,fungicide,112281-77-3,"(+-)-1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1H-1,2,4-triazole",FC(C(F)(OCC(C2=CC=C(C=C2Cl)Cl)CN1C=NC=N1)F)F,rat,50,fc; food concentration,104 weeks,10,0.5,80,3.400000095
+4897,37,Thiabendazol,Woodard,1964,JMPR,1970,benzimidazole,fungicide,148-79-8,2-(4-thiazolyl)-1H-benzimidazole,C2(C3=CSC=N3)=NC1=CC=CC=C1N2,rat,35,fd; food dose,104 weeks,0,10,0,40
+1142,358,Thiacloprid,Bomhard,1998,JMPR,2006,pyridine,insecticide,111988-49-9,3-(2-chloro-5-pyridylmethyl)-2-cyaniminothiazolidine,N#C/N=C1SCCN/1CC2=CC=C(Cl)N=C2,rat,50,fc; food concentration,108 weeks,25,1.200000048,50,2.5
+5913,308,Thiamethoxam,Bachmann,1998,JMPR,2010,guanidine,insecticide,153719-23-4,"3-[(2-chloro-5-thiazolyl)methyl]tetrahydro-5-methyl-N-nitro-4H-1,3,5-oxadiazin-4-imine",ClC1=NC=C(CN2/C(N(C)COC2)=N/[N+]([O-])=O)S1,rat,70,fc; food concentration,104 weeks,1000,50.29999924,3000,155
+1143,2045,Thiazopyr,,,USA,1997,pyridine,Herbicide,117718-60-2,"methyl 2-(difluoromethyl)-5-(4,5-dihydro-2-thiazolyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate",FC(F)C1=NC(C(F)(F)F)=C(C2=NCCS2)C(CC(C)C)=C1C(OC)=O,rat,,fc; food concentration,104 weeks,0,4.400000095,0,44.20000076
+6704,1016,Thiencarbazon-methyl,Schladt,2007,DAR,2012,triazole,Herbicide,317815-83-1,"methyl 4-[[[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carbonyl]amino]sulfonyl]-5-methyl-3-thiophenecarboxylic acid",O=S(NC(N1N=C(OC)N(C)C1=O)=O)(C2=C(C)SC=C2C(OC)=O)=O,rat,70,fc; food concentration,104 weeks,2500,115,5000,234
+1144,1040,Thiobencarb,Cummins,1984,DAR,2005,thiocarbamate,Herbicide,28249-77-6,S-[(4-chlorophenyl)methyl] diethylcarbamothioate,O=C(N(CC)CC)SCC1=CC=C(Cl)C=C1,rat,100,fc; food concentration,104 weeks,20,0.8999999762,100,4.300000191
+1145,40,Thiodicarb,Atkinson,1994,DAR,2005,"carbamate, oxime",insecticide,59669-26-0,"dimethyl N,N′-[thiobis[(methylimino)carbonyloxy]]bis[ethanimidothioate]",CS/C(C)=N/OC(N(SN(C(O/N=C(SC)\C)=O)C)C)=O,rat,15,fc; food concentration,52 weeks,0,0,60,5
+2988,40,Thiodicarb,DePass,1981,DAR,2005,"carbamate, oxime",insecticide,59669-26-0,"dimethyl N,N′-[thiobis[(methylimino)carbonyloxy]]bis[ethanimidothioate]",CS/C(C)=N/OC(N(SN(C(O/N=C(SC)\C)=O)C)C)=O,rat,120,fd; food dose,104 weeks,0,3,0,10
+2989,40,Thiodicarb,Atkinson,1994,DAR,2005,"carbamate, oxime",insecticide,59669-26-0,"dimethyl N,N′-[thiobis[(methylimino)carbonyloxy]]bis[ethanimidothioate]",CS/C(C)=N/OC(N(SN(C(O/N=C(SC)\C)=O)C)C)=O,rat,50,fc; food concentration,104 weeks,60,3,200,12
+1146,42,Thiophanat-methyl,Hashimoto,1972,JMPR,1995,"urea, thio",fungicide,23564-05-8,"dimethyl [1,2-phenylenebis(iminocarbonothioyl]bis[carbamate]",S=C(NC(OC)=O)NC(C=CC=C1)=C1NC(NC(OC)=O)=S,rat,35,fc; food concentration,104 weeks,160,8,640,32
+5422,42,Thiophanat-methyl,Takaori,1993,JMPR,1995,"urea, thio",fungicide,23564-05-8,"dimethyl [1,2-phenylenebis(iminocarbonothioyl]bis[carbamate]",S=C(NC(OC)=O)NC(C=CC=C1)=C1NC(NC(OC)=O)=S,rat,60,fc; food concentration,104 weeks,200,8.800000191,1200,53
+1147,43,Thiram,Miata,1991,JMPR,1992,dithiocarbamate,fungicide,137-26-8,tetramethylthioperoxydicarbonic diamide,S=C(SSC(N(C)C)=S)N(C)C,rat,64,fc; food concentration,104 weeks,30,1.200000048,300,12
+5565,43,Thiram,Kehoe,1991,JMPR,1992,dithiocarbamate,fungicide,137-26-8,tetramethylthioperoxydicarbonic diamide,S=C(SSC(N(C)C)=S)N(C)C,rat,60,fc; food concentration,104 weeks,30,1.5,150,7.300000191
+1148,111,Tolclofos-methyl,Pence,1982,DAR,2003,organophosphorus,fungicide,57018-04-9,"O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl phosphorothioate",COP(OC1=C(Cl)C=C(C)C=C1Cl)(OC)=S,rat,65,fc; food concentration,104 weeks,1000,42,0,0
+6859,2767,Tolfenpyrad,Chida,1999,JMPR,2013,pyrazole,Insecticide,129558-76-5,4-chloro-3-ethyl-1-methyl-N-[[4-(4-methylphenoxy)phenyl]methyl]-1H-pyrazole-5-carboxamide,,rat,60,fc; food concentration,104 weeks,15,0.5609999895,40,1.5
+1149,44,Tolylfluanid,Krötlinger,1982,DAR,2005,others,fungicide,731-27-1,"1,1-dichloro-N-[(dimethylamino)sulfonyl)]-1-fluroro-N-(4-methylphenyl)methanesulfenamide",CN(C)S(N(SC(F)(Cl)Cl)C1=CC=C(C)C=C1)(=O)=O,rat,50,fc; food concentration,104 weeks,300,20,1500,100
+2936,44,Tolylfluanid,Leser,1996,DAR,2005,others,fungicide,731-27-1,"1,1-dichloro-N-[(dimethylamino)sulfonyl)]-1-fluroro-N-(4-methylphenyl)methanesulfenamide",CN(C)S(N(SC(F)(Cl)Cl)C1=CC=C(C)C=C1)(=O)=O,rat,50,fc; food concentration,104 weeks,300,18,1500,90
+1150,936,Topramezon,Kspers,2002,DAR,2006,pyrazole,Herbicide,210631-68-8,"[3-(4,5-dihydro-3-isoxazolyl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)methanone",CC1=C(C2=NOCC2)C(S(C)(=O)=O)=CC=C1C(C3=C(O)N(C)N=C3)=O,rat,50,fc; food concentration,104 weeks,6,0.400000006,60,3.599999905
+1151,46,Tralkoxydim,Stonard,1994,DAR,2006,cyclohexanedione oxime,herbicide,87820-88-0,"2-[1-(ethoxyimino)propyl]-3-hydroxy-5-(2,4,6-trimethylphenyl)-2-cyclohexen-1-one",O=C1C(/C(CC)=N/OCC)=C(O)CC(C2=C(C)C=C(C)C=C2C)C1,rat,64,fc; food concentration,104 weeks,50,2.299999952,500,23
+1152,2049,Transfluthrin,,,UK,1997,pyrethrin,Insecticide,118712-89-3,"(2,3,5,6-tetrafluorophenyl)methyl (1R,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(C2C(/C=C(Cl)/Cl)C(C)2C)OCC1=C(F)C(F)=CC(F)=C1F,rat,,fc; food concentration,104 weeks,0,1,0,10
+1153,47,Triadimefon,Bomhard,1991,JMPR,2004,triazole,fungicide,43121-43-3,"1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triizol-1yl)-2-butanone",O=C(C(C)(C)C)C(N2C=NC=N2)OC1=CC=C(Cl)C=C1,rat,60,fc; food concentration,104 weeks,300,16.39999962,1800,114
+5001,47,Triadimefon,Bomhard,1978,JMPR,2004,triazole,fungicide,43121-43-3,"1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triizol-1yl)-2-butanone",O=C(C(C)(C)C)C(N2C=NC=N2)OC1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,50,2.380000114,500,24.29999924
+1154,62,Triadimenol,Kroetlinger,1994,DAR,2006,triazole,fungicide,55219-65-3,"beta-(4-chlorophenoxy)-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol",ClC1=CC=C(OC(N2N=CN=C2)C(O)C(C)(C)C)C=C1,rat,60,fc; food concentration,104 weeks,125,5,500,19
+1155,2009,Tri-allat,Stout,1989,DAR,2007,thiocarbamate,Herbicide,2303-17-5,"S-(2,3,3-trichloro-2-propenyl) bis(1-methylethyl)carbamothioate",O=C(SC/C(Cl)=C(Cl)\Cl)N(C(C)C)C(C)C,rat,60,fc; food concentration,104 weeks,50,2.5,250,13
+2864,2009,Tri-allat,Marias,1976,DAR,2007,thiocarbamate,Herbicide,2303-17-5,"S-(2,3,3-trichloro-2-propenyl) bis(1-methylethyl)carbamothioate",O=C(SC/C(Cl)=C(Cl)\Cl)N(C(C)C)C(C)C,rat,50,fc; food concentration,104 weeks,100,4.300000191,200,8.600000381
+1156,48,Triasulfuron,,,UK,1992,"urea, triazinylsulfonyl",herbicide,82097-50-5,"2-(2-chloroethoxy)-N-[[4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]benzenesulfonamide",ClCCOC1=CC=CC=C1S(NC(NC2=NC(OC)=NC(C)=N2)=O)(=O)=O,rat,,fc; food concentration,104 weeks,0,0.3000000119,0,30
+1157,146,Triazamate,Wolfe,1992,UK,1998,triazole,insecticide,112143-82-5,"ethyl[[1-[(dimethylamino)carbonyl]-3-(1,1-dimethylethyl)1H-1,2,4triazol-=5-yl]thio]acetate",O=C(OCC)CSC1=NC(C(C)(C)C)=NN1C(N(C)C)=O,rat,70,fc; food concentration,104 weeks,10,0.4499999881,250,12
+1158,49,Triazophos,Tennekes,1990,JMPR,2002,organophosphorus,insecticide,24017-47-8,"O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) phosphorothioate",CCOP(OC2=NN(C=N2)C1=CC=CC=C1)(OCC)=S,rat,80,fc; food concentration,104 weeks,3,0.150000006,27,1.299999952
+1159,943,Triazoxid,Eiben,1988,DAR,2007,imidazole,Fungicide,72459-58-6,"7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide",[O-][N+]2=NC(N3C=CN=C3)=NC1=CC=C(Cl)C=C12,rat,60,fc; food concentration,104 weeks,0,0,0,0.05000000075
+1160,1997,Tribenuron,Tobia,1987,DAR,2003,,,106040-48-6,,O=C(O)C1=CC=CC=C1S(=O)(NC(N(C2=NC(OC)=NC(C)=N2)C)=O)=O,rat,72,fc; food concentration,104 weeks,250,10,1250,55
+2834,51,Trichlorfon,Hayes,1989,DAR,2004,organophosphorus,insecticide,52-68-6,"dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate",OC(C(Cl)(Cl)Cl)P(OC)(OC)=O,rat,50,fc; food concentration,104 weeks,100,4.5,300,13.30000019
+2836,51,Trichlorfon,Christenson,1989,DAR,2004,organophosphorus,insecticide,52-68-6,"dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate",OC(C(Cl)(Cl)Cl)P(OC)(OC)=O,rat,50,fc; food concentration,104 weeks,0,0,0,0
+1161,975,Triclopyr,Philips,1984,DAR,2003,pyridine,Herbicide,55335-06-3,"[(3,5,6-trichloro-2-pyridinyl)oxy]acetic acid",O=C(O)COC1=NC(Cl)=C(Cl)C=C1Cl,rat,50,fd; food dose,104 weeks,0,30,0,0
+2776,975,Triclopyr,Eisenbrandt,1987,DAR,2003,pyridine,Herbicide,55335-06-3,"[(3,5,6-trichloro-2-pyridinyl)oxy]acetic acid",O=C(O)COC1=NC(Cl)=C(Cl)C=C1Cl,rat,50,fd; food dose,104 weeks,0,3,0,1
+1162,1034,Tricyclazol,Howard,1977,DAR,2007,triazole,Fungicide,41814-78-2,"5-methyl-1,2,4-triazolo[3,4-b]benzothiazole",CC1=C(N2C(S3)=NN=C2)C3=CC=C1,rat,40,fc; food concentration,104 weeks,275,11,620,26
+5017,352,Trifloxystrobin,Gerspach,1997,JMPR,2004,strobilurin,fungicide,141517-21-7,"(E,E)-alpha-(methoxyimino)-2-[[[[1-[3(trifluoromethyl)phenyl]-ethylidene]amino]oxy]methyl]-benzeneacetic acid methyl ester",CO\N=C(C(OC)=O)/C1=C(CO/N=C(C)/C2=CC=CC(C(F)(F)F)=C2)C=CC=C1,rat,50,fc; food concentration,104 weeks,250,9.800000191,750,29.70000076
+1164,53,Triflumizole,Virgo,1984,DAR,2006,imidazole,fungicide,68694-11-1,(E)-1-[1-[[4-chloro-2-(trifluoromethyl)phenyl]imino]-2-propoxyethyl]-1H-imidazole (CA),CCCOC/C(N2C=CN=C2)=N\C1=CC=C(C=C1C(F)(F)F)Cl,rat,70,fc; food concentration,104 weeks,100,3.5,400,14
+1165,112,Triflumuron,Krötlinger,1984,DAR,2005,"urea, benzoyl",insecticide,64628-44-0,2-chloro-N-[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]benzamide,FC(F)(F)OC(C=C2)=CC=C2NC(NC(C1=C(Cl)C=CC=C1)=O)=O,rat,50,fc; food concentration,104 weeks,20,0.8199999928,200,8.449999809
+1166,54,Trifluralin,Emmerson,1980,DAR,2003,dinitroaniline,herbicide,1582-09-8,"2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine",O=[N+]([O-])C1=CC(C(F)(F)F)=CC([N+]([O-])=O)=C1N(CCC)CCC,rat,30,fc; food concentration,104 weeks,0,0,813,30
+2682,54,Trifluralin,Worth,1966,DAR,2003,dinitroaniline,herbicide,1582-09-8,"2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine",O=[N+]([O-])C1=CC(C(F)(F)F)=CC([N+]([O-])=O)=C1N(CCC)CCC,rat,6,fc; food concentration,104 weeks,2000,84,20000,480
+2683,54,Trifluralin,Thomas,1978,DAR,2003,dinitroaniline,herbicide,1582-09-8,"2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine",O=[N+]([O-])C1=CC(C(F)(F)F)=CC([N+]([O-])=O)=C1N(CCC)CCC,rat,50,fc; food concentration,104 weeks,0,0,0,0
+6108,2786,Triflusulfuron,Biegel,1993,DAR,2007,,,,,,rat,62,fc; food concentration,104 weeks,100,4.059999943,750,30.60000038
+1167,116,Triflusulfuron-methyl,Biegel,1993,DAR,2007,"urea, triazinylsulfonyl",herbicide,126535-15-7,"2-(((((4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)-3-methylbenzoic acid",O=S(C1=C(C)C=CC=C1C(OC)=O)(NC(NC2=NC(OCC(F)(F)F)=NC(N(C)C)=N2)=O)=O,rat,62,fc; food concentration,104 weeks,100,4.059999943,750,30.60000038
+1168,55,Triforin,Everett,1992,JMPR,1997,others,fungicide,26644-46-2,"N,N'-[1,4-piperazinediylbis(2,2,2-trichloroethyidene)]bisformamide",ClC(Cl)(Cl)C(N1CCN(C(NC=O)C(Cl)(Cl)Cl)CC1)NC=O,rat,70,fc; food concentration,104 weeks,200,10,2000,100
+5274,55,Triforin,Hill,1974,JMPR,1997,others,fungicide,26644-46-2,"N,N'-[1,4-piperazinediylbis(2,2,2-trichloroethyidene)]bisformamide",ClC(Cl)(Cl)C(N1CCN(C(NC=O)C(Cl)(Cl)Cl)CC1)NC=O,rat,35,fc; food concentration,104 weeks,625,31,3120,160
+1169,71,Trinexapac-ethyl,Giknis,1992,DAR,2005,benzoic acid,plant growth regulator,95266-40-3,"ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate",O=C/1CC(C(O)=O)CC(C1=C(C2CC2)\O)=O,rat,90,fc; food concentration,104 weeks,3000,116,10000,393
+1170,147,Triticonazol,Aughton,1994,DAR,2005,triazole,fungicide,131983-72-7,"5-[(4-chlorophenyl)methylene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol",OC1(CN3N=CN=C3)C(C)(C)CC/C1=C\C2=CC=C(Cl)C=C2,rat,,fc; food concentration,104 weeks,750,29.39999962,5000,203.6000061
+6139,944,Tritosulfuron,Mellert,2001,DAR,2002,"urea, triazinylsulfonyl",Herbicide,142469-14-5,"N-[[[4-methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-yl]amino]carbonyl]-2-(trifluoromethyl)benzenesulfonamide",FC(F)(F)C1=CC=CC=C1S(NC(NC2=NC(C(F)(F)F)=NC(OC)=N2)=O)(=O)=O,rat,50,fc; food concentration,104 weeks,1000,48,3500,0
+6518,944,Tritosulfuron,Mellert,2001,DAR,2002,"urea, triazinylsulfonyl",Herbicide,142469-14-5,"N-[[[4-methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-yl]amino]carbonyl]-2-(trifluoromethyl)benzenesulfonamide",FC(F)(F)C1=CC=CC=C1S(NC(NC2=NC(C(F)(F)F)=NC(OC)=N2)=O)(=O)=O,rat,20,fc; food concentration,52 weeks,1000,51.70000076,3500,0
+6687,2051,Valifenalat,Webley,2004,EFSA,2012,acylamino acid,Fungicide,283159-90-0,"N-[(1-methylethoxy)carbonyl]-L-valyl-3-(4-chlorophenyl)-β-alanine, methyl ester",CC(C)OC(NC(C(C)C)C(NC(C1=CC=C(Cl)C=C1)CC(OC)=O)=O)=O,rat,50,fd; food dose,104 weeks,0,150,0,1000
+1171,57,Vinclozolin,Mellert,1993,JMPR,1995,dicarboximide,fungicide,50471-44-8,"(+-)-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione",O=C(OC(C)1C=C)N(C2=CC(Cl)=CC(Cl)=C2)C1=O,rat,20,fc; food concentration,104 weeks,50,2.799999952,150,8
+5410,57,Vinclozolin,Mellert,1994,JMPR,1995,dicarboximide,fungicide,50471-44-8,"(+-)-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione",O=C(OC(C)1C=C)N(C2=CC(Cl)=CC(Cl)=C2)C1=O,rat,50,fc; food concentration,104 weeks,0,0,50,2.700000048
+5480,58,Zineb,Blackwell-Smith,1953,JMPR,1993,"dithiocarbamate, alkylenebis",fungicide,12122-67-7,"[[1,2-ethanediylbis[carbamodithioato]](2-)]zinc",[S]C(NCCNC(S[Zn])=S)=S,rat,10,fc; food concentration,104 weeks,0,0,500,0
+5310,59,Ziram,NTP,1983,JMPR,1996,"dithiocarbamate, dimethyl",fungicide,137-30-4,"(T-4)-bis(dimethyldithiocarbamato-S,S')zinc",CN(C)C(S[Zn]SC(N(C)C)=S)=S,rat,50,fc; food concentration,104 weeks,0,0,300,13
+5311,59,Ziram,Powell,1994,JMPR,1996,"dithiocarbamate, dimethyl",fungicide,137-30-4,"(T-4)-bis(dimethyldithiocarbamato-S,S')zinc",CN(C)C(S[Zn]SC(N(C)C)=S)=S,rat,70,fc; food concentration,104 weeks,0,0,60,2.5
+1172,312,Zoxamid,Ivett,1998,JMPR,2007,carboxamide,fungicide,156052-68-5,"N-(1-chloro-3-methyl-e-oxopent-3-yl)-3,5-dichloro-4-methylbezamide",CC(C(Cl)=C1)=C(Cl)C=C1C(NC(C)(CC)C(CCl)=O)=O,rat,70,fc; food concentration,104 weeks,20000,1058,0,0
\ No newline at end of file diff --git a/data/Copy of NOAEL-LOAEL.xlsx b/data/Copy of NOAEL-LOAEL.xlsx Binary files differnew file mode 100644 index 0000000..be6065a --- /dev/null +++ b/data/Copy of NOAEL-LOAEL.xlsx diff --git a/data/NOAEL-LOAEL_SMILES_rat_chron.csv b/data/NOAEL-LOAEL_SMILES_rat_chron.csv new file mode 100644 index 0000000..a6b3005 --- /dev/null +++ b/data/NOAEL-LOAEL_SMILES_rat_chron.csv @@ -0,0 +1,579 @@ +ID NOAEL,ID Stoff,compound,author,study year,evaluator,evaluation year,class,function,CASNR,CAS name,SMILES,species,n,regimen,study type,Np_conc,Np_dose,Lp_conc,Lp_dose
+6901,2233,"1,4-Dimethylnaphtalene",Mallet,2011,DAR,2012,,,571-58-4,,CC1=CC=C(C2=CC=CC=C12)C,rat,85,fc; food concentration,104 weeks,150,10,500,27
+5829,410,2-(1-naphthyl)acetic acid,Drummond,1996,DAR,2010,auxin,plant growth regulator,86-87-3,1-naphthaleneacetic acid,O=C(O)CC2=CC=CC1=CC=CC=C12,rat,80,fc; food concentration,104 weeks,1000,43.79999924,5000,224.5
+5386,216,"2,4-D",Hansen,1971,JMPR,1996,"alkanoic acid, aryloxy",herbicide,94-75-7,"(2,4-dichlorophenoxy)acetic acid",ClC1=CC(Cl)=C(OCC(O)=O)C=C1,rat,25,fc; food concentration,104 weeks,625,31,1250,62
+5387,216,"2,4-D",Serota,1986,JMPR,1996,"alkanoic acid, aryloxy",herbicide,94-75-7,"(2,4-dichlorophenoxy)acetic acid",ClC1=CC(Cl)=C(OCC(O)=O)C=C1,rat,50,fd; food dose,104 weeks,0,1,0,5
+5388,216,"2,4-D",Jeffries,1995,JMPR,1996,"alkanoic acid, aryloxy",herbicide,94-75-7,"(2,4-dichlorophenoxy)acetic acid",ClC1=CC(Cl)=C(OCC(O)=O)C=C1,rat,50,fd; food dose,104 weeks,0,5,0,75
+880,60,Abamectin,Gordon,1985,DAR,2006,avermectin,insecticide,71751-41-2,avermectin B1a + avermectin B1b,CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C.CC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)O)OC)OC)C)OC7(C4)C=CC(C(O7)C(C)C)C)O,rat,50,fd; food dose,104 weeks,0,1.5,0,2
+5083,266,Acephat,Auletta,1981,JMPR,2002,organophosphorus,insecticide,30560-19-1,N-[methoxy(methylthio)phosphinoyl]acetamide,O=P(SC)(OC)NC(C)=O,rat,75,fc; food concentration,120 weeks,5,0.25,50,2.5
+881,340,Acequinocyl,Inoue,1997,DAR,2005,quinone,acaricide,57960-19-7,"2-(acetyloxy)-3-dodecyl-1,4-naphthalenedione",O=C2C(CCCCCCCCCCCC)=C(OC(C)=O)C(C1=CC=CC=C12)=O,rat,50,fc; food concentration,104 weeks,50,2.299999952,200,9
+882,164,Acetamiprid,Hatch,1999,JMPR,2011,pyridine,insecticide,135410-20-7,(E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine,ClC1=CC=C(CN(C)/C(C)=N/C#N)C=N1,rat,60,fc; food concentration,104 weeks,160,7.099999905,400,17.5
+883,1,Acetochlor,Naylor,1986,DAR,2006,chloroacetanilide,herbicide,34256-82-1,2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)acetamide,O=C(N(COCC)C1=C(CC)C=CC=C1C)CCl,rat,60,fc; food concentration,104 weeks,200,9.399999619,1000,47.5
+2555,1,Acetochlor,Ahmed,1983,DAR,2006,chloroacetanilide,herbicide,34256-82-1,2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)acetamide,O=C(N(COCC)C1=C(CC)C=CC=C1C)CCl,rat,60,fc; food concentration,104 weeks,500,22,1500,69
+2556,1,Acetochlor,Broadmeadow,1989,DAR,2006,chloroacetanilide,herbicide,34256-82-1,2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)acetamide,O=C(N(COCC)C1=C(CC)C=CC=C1C)CCl,rat,50,fc; food concentration,104 weeks,175,6.369999886,1750,66.90000153
+884,184,Acibenzolar-S-methyl,Anonymous,1996,DAR,2013,others,fungicide,135158-54-2,"1,2,3-benzothiadiazole-7-thiocarbxylic acid S-methyl ester",CSC(C1=C2C(N=NS2)=CC=C1)=O,rat,,fc; food concentration,104 weeks,200,7.769999981,2500,96.90000153
+885,33,Aclonifen,Kirsch,1989,DAR,2006,diphenyl ether,herbicide,74070-46-5,2-chloro-6-nitro-3-phenoxybenzenamine,NC1=C(C(OC2=CC=CC=C2)=CC=C1[N+]([O-])=O)Cl,rat,50,fc; food concentration,104 weeks,40,1.600000024,200,8
+2565,33,Aclonifen,Wason,2004,DAR,2006,diphenyl ether,herbicide,74070-46-5,2-chloro-6-nitro-3-phenoxybenzenamine,NC1=C(C(OC2=CC=CC=C2)=CC=C1[N+]([O-])=O)Cl,rat,60,fc; food concentration,104 weeks,200,7.599999905,1600,62
+2505,130,Acrinathrin,Cooper,2004,DAR,2007,pyrethroid,acaricide,101007-06-1;103833-18-7unstatedstereochemistry,"2,2-dimethyl-3-[3-oxo-3-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-1-propenyl]cyclopropanecarboxylate",FC(F)(F)C(C(F)(F)F)OC(/C=C\C1C(C)(C)C1C(OC(C#N)C2=CC=C(OC3=CC=CC=C3)C=C2)=O)=O,rat,60,fc; food concentration,104 weeks,30,1.600000024,150,8.100000381
+2567,130,Acrinathrin,Vallet,1991,DAR,2007,pyrethroid,acaricide,101007-06-1;103833-18-7unstatedstereochemistry,"2,2-dimethyl-3-[3-oxo-3-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-1-propenyl]cyclopropanecarboxylate",FC(F)(F)C(C(F)(F)F)OC(/C=C\C1C(C)(C)C1C(OC(C#N)C2=CC=C(OC3=CC=CC=C3)C=C2)=O)=O,rat,50,fc; food concentration,104 weeks,90,4.599999905,0,0
+886,144,Alachlor,,,UK,1991,chloroacetanilide,herbicide,15972-60-8,"2-chloro-N-(2,6diethylphenyl)-N-(methoxymethyl)acetanilide",O=C(N(C1=C(CC)C=CC=C1CC)COC)CCl,rat,50,fd; food dose,104 weeks,0,0.5,0,2.5
+4797,144,Alachlor,,,UK,1991,chloroacetanilide,herbicide,15972-60-8,"2-chloro-N-(2,6diethylphenyl)-N-(methoxymethyl)acetanilide",O=C(N(C1=C(CC)C=CC=C1CC)COC)CCl,rat,50,fd; food dose,104 weeks,0,0,0,14
+4798,144,Alachlor,,,UK,1991,chloroacetanilide,herbicide,15972-60-8,"2-chloro-N-(2,6diethylphenyl)-N-(methoxymethyl)acetanilide",O=C(N(C1=C(CC)C=CC=C1CC)COC)CCl,rat,,fd; food dose,104 weeks,0,0,0,126
+4505,2159,alpha-Chlorohydrin,Weisburger,1981,USA,2006,,rodenticide,96-24-2,"3-chloro-1,2-propanediol",C(C(CCl)O)O,rat,,gc; gavage concentration,72 weeks,0,0,0,30
+4506,2159,alpha-Chlorohydrin,Sunahara,1993,USA,2006,,rodenticide,96-24-2,"3-chloro-1,2-propanediol",C(C(CCl)O)O,rat,,wc; water concentration,104 weeks,0,0,0,1.100000024
+6323,2055,Ametoctradin,not given,2008,EU,2012,,fungicide,865318-97-4,"5-ethyl-6-octyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine",NC2=C(CCCCCCCC)C(CC)=NC1=NC=NN12,rat,60,fc; food concentration,104 weeks,15000,871,0,0
+5801,2160,Amicarbazone,,,USA,2005,triazolone,herbicide,129909-90-6,"4-amino-N-(1,1-dimethylethyl)-4,5-dihydro-3-(1-methylethyl)-5-oxo-1H-1,2,4-triazole-1-carboxamide",CC(C)C1=NN(C(=O)N1N)C(=O)NC(C)(C)C,rat,,fc; food concentration,104 weeks,50,2.299999952,500,25.29999924
+888,198,Amidosulfuron,Dotti,1992,DAR,2006,"urea, sulfonyl",herbicide,120923-37-7,"N-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-N-methylmethanesulfonamide",O=S(N(C)S(C)(=O)=O)(NC(NC1=NC(OC)=CC(OC)=N1)=O)=O,rat,50,fc; food concentration,104 weeks,2000,97.80000305,10000,495.3999939
+2578,991,Aminopyralid,Johnson,2004,DAR,2008,pyridine,herbicide,150114-71-9;566191-87-5(Kalium-),"4-amino-3,6-dichloro-2-pyridinecarboxylic acid",OC(C1=NC(Cl)=CC(N)=C1Cl)=O,rat,50,fd; food dose,104 weeks,0,500,0,1000
+2600,992,Amisulbrom,Blee,2005,DAR,2012,triazole,fungicide,348635-87-0,"3-[(3-bromo-6-fluoro-2-methyl-1H-indol-1-yl)sulfonyl]-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide",CN(C)S(N(C=N3)N=C3S(N2C(C)=C(Br)C1=CC=C(F)C=C12)(=O)=O)(=O)=O,rat,70,fc; food concentration,104 weeks,200,11.10000038,2000,112
+890,212,Amitraz,Sutton,1973,JMPR,1998,amidine,insecticide,33089-61-1,"N'-(2,4-dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methylmethanimidamide",CN(/C=N/C(C=CC(C)=C2)=C2C)/C=N/C(C=CC(C)=C1)=C1C,rat,40,fc; food concentration,104 weeks,50,2.5,200,10
+891,75,Amitrol,Keller,1959,JMPR,1997,triazole,herbicide,61-82-5,"1H-1,2,4-triazol-3-amine",NC1=NNC=N1,rat,35,fc; food concentration,104 weeks,10,0.5,50,2.5
+5556,75,Amitrol,Steinhoff,1979,JMPR,1993,triazole,herbicide,61-82-5,"1H-1,2,4-triazol-3-amine",NC1=NNC=N1,rat,75,fc; food concentration,104 weeks,10,0.5,100,5
+892,218,Anilazin,Goodyer,1984,JMPR,1989,triazine,fungicide,101-05-3,"4,6-dichloro-N-(2-chlorophenyl)-1,3,5-triazin-2-amine",ClC2=C(C=CC=C2)NC1=NC(Cl)=NC(Cl)=N1,rat,60,fc; food concentration,104 weeks,2000,100,0,0
+893,402,Asulam,Hunter,1981,DAR,2006,carbamate,herbicide,3337-71-1,methyl [(4-aminophenyl)sulfonyl]carbamate,O=C(OC)NS(C1=CC=C(N)C=C1)(=O)=O,rat,75,fc; food concentration,104 weeks,1000,36,5000,180
+894,408,Atrazin,Mayhew,1986,JMPR,2007,triazine,herbicide,1912-24-9,"6-chloro-N-ethyl-N´-(1-methylethyl)-1,3,5-triazine-2,4-diamine",CCNC1=NC(NC(C)C)=NC(Cl)=N1,rat,70,fc; food concentration,104 weeks,25,1.5,50,3.099999905
+4771,408,Atrazin,,,JMPR,2007,triazine,herbicide,1912-24-9,"6-chloro-N-ethyl-N´-(1-methylethyl)-1,3,5-triazine-2,4-diamine",CCNC1=NC(NC(C)C)=NC(Cl)=N1,rat,,fc; food concentration,104 weeks,70,3.5,200,10
+4814,408,Atrazin,Rudzky,1991,JMPR,2007,triazine,herbicide,1912-24-9,"6-chloro-N-ethyl-N´-(1-methylethyl)-1,3,5-triazine-2,4-diamine",CCNC1=NC(NC(C)C)=NC(Cl)=N1,rat,50,fc; food concentration,104 weeks,50,2.299999952,500,23.60000038
+895,954,Azaconazol,,,UK,1988,azole,fungicide,60207-31-0,"1-[[2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole",ClC1=C(C3(OCCO3)CN2C=NC=N2)C=CC(Cl)=C1,rat,,fc; food concentration,104 weeks,0,3.200000048,0,12.80000019
+3878,945,Azadirachtin,Kumar,2000,DAR,2009,others,insecticide,11141-17-6,"dimethyl (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-",CC=C(C)C(=O)OC1CC(C2(COC3C2C14COC(C4C(C3O)(C)C56C7CC(C5(O6)C)C8(C=COC8O7)O)(C(=O)OC)O)C(=O)OC)OC(=O)C,rat,50,fc; food concentration,104 weeks,6400,448,0,0
+2629,980,Azimsulfuron,Inui,1994,DAR,2009,"urea, sulfonyl",herbicide,120162-55-2,,COC1=NC(NC(NS(C2=C(C3=NN(C)N=N3)C=NN2C)(=O)=O)=O)=NC(OC)=C1,rat,,fc; food concentration,104 weeks,1000,43.29999924,5000,0
+896,422,Azinphos-methyl,Schmidt,1987,JMPR,2007,organophosphorus,insecticide,86-50-0,"0,0-dimethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] phosphorodithioate",S=P(OC)(OC)SCN1N=NC(C=CC=C2)=C2C1=O,rat,60,fc; food concentration,104 weeks,15,0.8999999762,45,2.700000048
+4916,433,Azocyclotin,Bomhard,1979,JMPR,2005,organotin,acaricide,41083-11-8,"1-(tricyclohexylstannyl)-1H-1,2,4-triazole",N4(N=CN=C4)[Sn](C2CCCCC2)(C3CCCCC3)C1CCCCC1,rat,50,fc; food concentration,104 weeks,5,0.2599999905,15,0.7900000215
+2614,298,Azoxystrobin,Milburn,1995,DAR,2009,strobilurin,fungicide,131860-33-8,methyl (E)-2-[[6-(2-cyanophenoxy)-4-pyrimidinyl]oxy]alpha-methoxymethylene)benzeneacetate,O=C(OC)/C(C1=CC=CC=C1OC2=CC(OC3=CC=CC=C3C#N)=NC=N2)=C/OC,rat,52,fc; food concentration,104 weeks,300,18.20000076,1500,82.40000153
+7080,2889,BAM,Wheldon,1971,EFSA,2005,,,,,NC(C1=C(Cl)C=CC=C1Cl)=O,rat,35,fc; food concentration,104 weeks,180,5.699999809,500,17.60000038
+6125,937,Beflubutamid,Barker,2000,DAR,2002,amide,herbicide,113614-08-7,2-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(phenylmethyl)butanamide,FC(F)(F)C1=C(F)C=CC(OC(CC)C(NCC2=CC=CC=C2)=O)=C1,rat,60,,104 weeks,50,2.200000048,400,17.70000076
+898,435,Benalaxyl,Thompson,1983,JMPR,2005,phenylamide,fungicide,71626-11-4,"methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-DL-alaninate",COC(C(N(C2=C(C)C=CC=C2C)C(CC1=CC=CC=C1)=O)C)=O,rat,65,fc; food concentration,104 weeks,1000,44,0,0
+899,441,Bendiocarb,,,UK,2005,carbamate,insecticide,22781-23-3,"2,2-dimethyl-1,3-benzodioxol-4-yl methylcarbamate",CC2(C)OC1=CC=CC(OC(NC)=O)=C1O2,rat,,fc; food concentration,104 weeks,0,0.400000006,0,0.8000000119
+900,1041,Benfluralin,Moore,1996,DAR,2006,dinitroaniline,herbicide,1861-40-1,"N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)benzenamine",CCN(CCCC)C1=C([N+]([O-])=O)C=C(C(F)(F)F)C=C1[N+]([O-])=O,rat,60,fc; food concentration,104 weeks,10,0.5,100,5.400000095
+901,76,Benfuracarb,Cox,1984,DAR,2005,carbamate,insecticide,82560-54-1,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl 2-methyl-4-(1-methylethyl)-7-oxo-8-oxa-3-thia-2,4-diazadecanoate",CCOC(CCN(C(C)C)SN(C)C(OC1=CC=CC2=C1OC(C)(C)C2)=O)=O,rat,50,fc; food concentration,104 weeks,100,5.5,0,11
+2396,76,Benfuracarb,Cox,1983,DAR,2005,carbamate,insecticide,82560-54-1,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl 2-methyl-4-(1-methylethyl)-7-oxo-8-oxa-3-thia-2,4-diazadecanoate",CCOC(CCN(C(C)C)SN(C)C(OC1=CC=CC2=C1OC(C)(C)C2)=O)=O,rat,10,fc; food concentration,52 weeks,200,11.89000034,400,24
+2641,76,Benfuracarb,Cox,1986,DAR,2005,carbamate,insecticide,82560-54-1,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl 2-methyl-4-(1-methylethyl)-7-oxo-8-oxa-3-thia-2,4-diazadecanoate",CCOC(CCN(C(C)C)SN(C)C(OC1=CC=CC2=C1OC(C)(C)C2)=O)=O,rat,50,fc; food concentration,104 weeks,25,1.5,0,0
+5369,446,Benomyl,Sherman,1977,JMPR,1995,benzimidazole,fungicide,17804-35-2,methyl [1-[(butylamino)carbonyl]-1H-benzimidazol-2-yl]carbamate,O=C(NCCCC)N1C(NC(OC)=O)=NC2=C1C=CC=C2,rat,36,fc; food concentration,104 weeks,2500,109,0,0
+903,1042,Bensulfuron,Stadler,1986,DAR,2006,"urea, sulfonyl",herbicide,99283-01-9,"2-[[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]methyl]benzoic acid",COC1=CC(OC)=NC(NC(NS(CC2=CC=CC=C2C(O)=O)(=O)=O)=O)=N1,rat,80,fc; food concentration,104 weeks,750,30,7500,309
+5678,457,Bentazon,Takehara,1984,JMPR,1991,others,herbicide,25057-89-0,"3-(1-methylethyl)-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide",CC(C)N2C(C1=CC=CC=C1NS(=O)2=O)=O,rat,50,fc; food concentration,104 weeks,200,9,800,36
+904,324,Benthiavalicarb-isopropyl,Murata,2001,DAR,2005,carbamate,fungicide,177406-68-7,Isopropyl[(1S)-1-[[[(1R)-1-(6-fluoro-2-benzothiazolyl)ethyl]amino]carbonyl]-2-methylpropyl]carbamic acid,FC1=CC=C2C(SC(C(C)NC(C(C(C)C)NC(OC(C)C)=O)=O)=N2)=C1,rat,80,fc; food concentration,104 weeks,200,9.899999619,5000,249.6000061
+6779,2851,Benzovindiflupyr,Mackay,2012,JMPR,2013,pyrazole,fungicide,1072957-71-1,"N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide",CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC3=C2C4CCC3C4=C(Cl)Cl,rat,64,fc; food concentration,104 weeks,100,4.900000095,600,30.20000076
+2406,988,Bifenazat,Ivett,1999,DAR,2003,others,acaricide,149877-41-8,"1-methylethyl 2-(4-methoxy[1,1′-biphenyl]-3-yl)hydrazinecarboxylate",COC(C(NNC(OC(C)C)=O)=C2)=CC=C2C1=CC=CC=C1,rat,60,fc; food concentration,104 weeks,20,1,80,3.900000095
+906,90,Bifenox,Ruckman,1987,DAR,2006,diphenyl ether,herbicide,42576-02-3,"methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate",COC(C1=C([N+]([O-])=O)C=CC(OC2=C(Cl)C=C(Cl)C=C2)=C1)=O,rat,50,fc; food concentration,104 weeks,1580,59,5000,187
+908,93,Bifenthrin,McCarthy,1986,DAR,2006,pyrethroid,insecticide,82657-04-3,"[1alpha,3alpha(Z)]-(+/-)-(2-methyl[1,1'-biphenyl]-3-yl)methyl 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate",CC1=C(C3=CC=CC=C3)C=CC=C1COC(C2C(C(C)2C)/C=C(C(F)(F)F)\Cl)=O,rat,50,fc; food concentration,104 weeks,100,4.699999809,200,0
+5671,1030,Bioresmethrin,Vallet,1990,JMPR,1991,pyrethroid,insecticide,28434-01-7,"[5-(phenylmethyl)-3-furanyl]methyl (1R,3R)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate",CC1(C)C(C(OCC2=COC(CC3=CC=CC=C3)=C2)=O)C1/C=C(C)\C,rat,50,fc; food concentration,104 weeks,50,3,250,15
+4410,2157,Bispyribac,Inoue,1995,DAR,2005,,,125401-92-5,,COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+],rat,58,fc; food concentration,104 weeks,20,1.100000024,200,13.80000019
+2421,72,Bitertanol,Bomhard,1981,DAR,2006,triazole,fungicide,55179-31-2,"beta-([1,1'-biphenyl]-4-yloxy)-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol",CC(C)(C(C(N3C=NC=N3)OC1=CC=C(C2=CC=CC=C2)C=C1)O)C,rat,50,fc; food concentration,104 weeks,100,4.900000095,500,25
+3910,2050,Bixafen,Elligott,2008,DAR,2011,pyrazole,fungicide,581809-46-3,"N-(3′,4′-dichloro-5-fluoro[1,1′-biphenyl]-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide",ClC1=CC=C(C2=CC(F)=CC=C2NC(C3=CN(C)N=C3C(F)F)=O)C=C1Cl,rat,70,fc; food concentration,104 weeks,50,2.799999952,300,17.39999962
+3911,2050,Bixafen,Elligott,2008,DAR,2011,pyrazole,fungicide,581809-46-3,"N-(3′,4′-dichloro-5-fluoro[1,1′-biphenyl]-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide",ClC1=CC=C(C2=CC(F)=CC=C2NC(C3=CN(C)N=C3C(F)F)=O)C=C1Cl,rat,70,fc; food concentration,104 weeks,50,2,300,12.10000038
+6611,322,Boscalid,Mellert,2001,DAR,2002,anilide,fungicide,188425-85-6,"2-chloro-N-(4′-chloro[1,1′-biphenyl]-2-yl)-3-pyridinecarboxamide",ClC(N=CC=C3)=C3C(NC1=CC=CC=C1C2=CC=C(Cl)C=C2)=O,rat,20,fc; food concentration,78 weeks,100,4.400000095,500,13
+6629,322,Boscalid,Mellert,2001,DAR,2002,anilide,fungicide,188425-85-6,"2-chloro-N-(4′-chloro[1,1′-biphenyl]-2-yl)-3-pyridinecarboxamide",ClC(N=CC=C3)=C3C(NC1=CC=CC=C1C2=CC=C(Cl)C=C2)=O,rat,50,fc; food concentration,104 weeks,100,4.599999905,500,0
+6634,322,Boscalid,Mellert,2001,DAR,2002,anilide,fungicide,188425-85-6,"2-chloro-N-(4′-chloro[1,1′-biphenyl]-2-yl)-3-pyridinecarboxamide",ClC(N=CC=C3)=C3C(NC1=CC=CC=C1C2=CC=C(Cl)C=C2)=O,rat,20,fc; food concentration,104 weeks,100,4.400000095,500,0
+4954,2181,Bromacil,,,USA,1996,uracil,herbicide,314-40-9,"5-bromo-6-methyl-3-(1-methylpropyl)-2,4(1H,3H)-pyrimidinedione",CCC(C)N1C(=O)C(=C(NC1=O)C)Br,rat,,fc; food concentration,104 weeks,250,9.819999695,2500,103
+911,189,Bromopropylat,Basler,1989,JMPR,1993,benzilate,acaricide,18181-80-1,1-methylethyl 4-bromo-alpha-(4-bromophenyl)-alpha-hydroxybenzeneacetate,CC(OC(C(C1=CC=C(Br)C=C1)(C2=CC=C(Br)C=C2)O)=O)C,rat,80,fc; food concentration,104 weeks,100,3.700000048,700,25.89999962
+5545,189,Bromopropylat,Coulston,1970,JMPR,1993,benzilate,acaricide,18181-80-1,1-methylethyl 4-bromo-alpha-(4-bromophenyl)-alpha-hydroxybenzeneacetate,CC(OC(C(C1=CC=C(Br)C=C1)(C2=CC=C(Br)C=C2)O)=O)C,rat,50,fc; food concentration,104 weeks,0,0,0,0
+2432,190,Bromoxynil,Hamada,1986,DAR,,hydroxybenzonitrile,herbicide,1689-84-5,"3,5-dibromo-4-hydroxybenzonitrile",BrC1=CC(C#N)=CC(Br)=C1O,rat,70,fc; food concentration,104 weeks,60,2.599999905,190,8
+912,998,Bromuconazol,Broadmeadow,1992,DAR,2006,azole,fungicide,116255-48-2,"1-[[4-bromo-2-(2,4-dichlorophenyl)tetrahydro-2-furanyl]methyl]-1H-1,2,4-triazole",BrC(C3)COC(CN2C=NC=N2)3C1=C(Cl)C=C(Cl)C=C1,rat,40,fc; food concentration,104 weeks,20,0.8799999952,150,6.480000019
+913,192,Bupirimate,Ben-Dyke,1976,DAR,2007,pyrimidine,fungicide,41483-43-6,5-butyl-2-(ethylamino)-6-methyl-4-pyrimidinyl dimethylsulfamate,CCCCC1=C(OS(=O)(N(C)C)=O)N=C(NCC)N=C1C,rat,40,fc; food concentration,104 weeks,1000,25,5000,156
+914,193,Buprofezin,Watanabe,1982,DAR,2006,others,insecticide,953030-84-7,"2-[(1,1-dimethylethyl)imino]tetrahydro-3-(1-methylethyl)-5-phenyl-4H-1,3,5-thiadiazin-4-one",O=C(N1C(C)C)N(C2=CC=CC=C2)CS/C1=N\C(C)(C)C,rat,40,fc; food concentration,104 weeks,20,0.8999999762,200,9
+915,194,Butralin,Fogleman,1974,DAR,2006,"2,6-dinitroaniline",herbicide,33629-47-9,"4-(1,1-dimethylethyl)-N-(1-methylpropyl)-2,6-dinitrobenzenamine",CCC(NC1=C([N+]([O-])=O)C=C(C(C)(C)C)C=C1[N+]([O-])=O)C,rat,35,fc; food concentration,104 weeks,500,20.29999924,1000,40.59999847
+916,78,Cadusafos,Weiner,1986,DAR,2004,organophosphorus,insecticide,95465-99-9,"O-ethyl S,S-bis(1-methylpropyl) phosphorodithioate",O=P(OCC)(SC(C)CC)SC(C)CC,rat,60,fc; food concentration,104 weeks,1,0.04500000179,5,0.2220000029
+917,196,Captan,Benson,1982,DAR,2005,N-trihalomethylthio,fungicide,133-06-2,"3a,4,7,7a-tetrahydro-2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",ClC(Cl)(Cl)SN(C1=O)C(C2C1CC=CC2)=O,rat,50,fd; food dose,104 weeks,0,25,0,100
+2711,196,Captan,Til,1983,DAR,2005,N-trihalomethylthio,fungicide,133-06-2,"3a,4,7,7a-tetrahydro-2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",ClC(Cl)(Cl)SN(C1=O)C(C2C1CC=CC2)=O,rat,50,fc; food concentration,130 weeks,500,24,2000,98
+918,197,Carbaryl,Hamada,1993,DAR,2005,carbamate,insecticide,63-25-2,1-naphthalenyl methylcarbamate,O=C(NC)OC1=C(C=CC=C2)C2=CC=C1,rat,80,fc; food concentration,104 weeks,250,10,1500,60.20000076
+5859,110,Carbendazim,Til,1976,DAR,2009,benzimidazole,fungicide,10605-21-7,methyl 1H-benzimidazol-2-ylcarbamate,O=C(OC)NC2=NC1=CC=CC=C1N2,rat,60,fc; food concentration,104 weeks,10000,599.7999878,0,0
+5860,110,Carbendazim,Sherman,1972,DAR,2009,benzimidazole,fungicide,10605-21-7,methyl 1H-benzimidazol-2-ylcarbamate,O=C(OC)NC2=NC1=CC=CC=C1N2,rat,36,fc; food concentration,104 weeks,500,22,5000,250
+920,113,Carbetamid,Amyes,1988,DAR,2006,carbamate,herbicide,16118-49-3,(R)-N-ethyl-2-[[(phenylamino)carbonyl]oxy]propanamide,O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C,rat,60,fc; food concentration,104 weeks,160,7,1200,55
+921,118,Carbofuran,Spicer,1991,DAR,2004,carbamate,insecticide,1563-66-2,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate",O=C(NC)OC1=C(OC(C)(C)C2)C2=CC=C1,rat,60,fc; food concentration,104 weeks,10,0.4620000124,20,1.169999957
+2483,118,Carbofuran,Goldenthal,1979,DAR,2004,carbamate,insecticide,1563-66-2,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate",O=C(NC)OC1=C(OC(C)(C)C2)C2=CC=C1,rat,90,fc; food concentration,104 weeks,20,1,100,5
+2491,127,Carbosulfan,Norvell,1982,DAR,2004,carbamate,insecticide,55285-14-8,"2,3-dihydro-2,2-dimethyl-7-benzofuranyl [(dibutylamino)thio]methylcarbamate",CCCCN(SN(C(OC2=C1OC(C)(C)CC1=CC=C2)=O)C)CCCC,rat,90,fc; food concentration,104 weeks,20,1,500,25
+923,129,Carboxin,Kehoe,1991,DAR,2006,carboxamide,fungicide,5234-68-4,"5,6-dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide",O=C(C(SCCO2)=C2C)NC1=CC=CC=C1,rat,60,fc; food concentration,104 weeks,20,0.8199999928,200,8.199999809
+924,297,Carfentrazone-ethyl,Hill,1995,USA,1998,others,herbicide,128639-02-1,"Ethyl 2-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorobenzenepropanoate",O=C(OCC)C(Cl)CC1=CC(N2N=C(C)N(C(F)F)C2=O)=C(F)C=C1Cl,rat,70,fc; food concentration,104 weeks,50,3,200,12
+4530,1028,Chlorantraniliprol,,,USA,2008,pyrazole,insecticide,500008-45-7,3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide,BrC1=NN(C2=NC=CC=C2Cl)C(C(NC3=C(C(NC)=O)C=C(Cl)C=C3C)=O)=C1,rat,,fc; food concentration,104 weeks,0,805,0,0
+5757,135,Chlordan,Ihui,1983,JMPR,1986,cyclodiene organochlorine,insecticide,57-74-9,"1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene",ClC2(C(Cl)3Cl)C(Cl)=C(Cl)C3(Cl)C1C(Cl)C(Cl)CC12,rat,80,fc; food concentration,130 weeks,1,0,5,0
+925,176,Chlorfenapyr,Trutter,1994,JMPR,2012,pyrazole,insecticide,122453-73-0,4-bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile,ClC(C=C2)=CC=C2C1=C(C#N)C(Br)=C(C(F)(F)F)N1COCC,rat,65,fc; food concentration,104 weeks,60,2.900000095,300,15
+926,63,Chlorfenvinphos,Pickering,1980,JMPR,1994,organophosphorus,insecticide,470-90-6,"2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl phosphate",O=P(OCC)(OCC)O/C(C1=CC=C(Cl)C=C1Cl)=C/Cl,rat,50,fc; food concentration,104 weeks,3,0.150000006,30,1.5
+927,154,Chloridazon,Hunter,1977,DAR,2005,pyridazinone,herbicide,1698-60-8,5-amino-4-chloro-2-phenyl-3(2H)-pyridazinone,O=C1C(Cl)=C(N)C=NN1C2=CC=CC=C2,rat,40,fc; food concentration,104 weeks,450,20,1350,60
+2518,154,Chloridazon,Mellert,1993,DAR,2005,pyridazinone,herbicide,1698-60-8,5-amino-4-chloro-2-phenyl-3(2H)-pyridazinone,O=C1C(Cl)=C(N)C=NN1C2=CC=CC=C2,rat,50,fc; food concentration,104 weeks,300,13,1000,50
+928,160,Chlormequat,Schilling,1992,DAR,2007,quaternary ammonium,plant growth regulator,999-81-5,"2-chloro-N,N,N-trimethylethanaminium",C[N+](C)(C)CCCl.[Cl-],rat,20,fc; food concentration,78 weeks,937,43,2811,136
+2532,160,Chlormequat,Mellert,1992,DAR,2007,quaternary ammonium,plant growth regulator,999-81-5,"2-chloro-N,N,N-trimethylethanaminium",C[N+](C)(C)CCCl.[Cl-],rat,50,fc; food concentration,104 weeks,937,42,2811,125
+2732,160,Chlormequat,,1979,DAR,2007,quaternary ammonium,plant growth regulator,999-81-5,"2-chloro-N,N,N-trimethylethanaminium",C[N+](C)(C)CCCl.[Cl-],rat,50,fc; food concentration,104 weeks,0,0,1500,75
+2740,1038,Chloropicrin,Slauter,1995,DAR,2006,others,fungicide,76-06-2,trichloronitromethane,O=[N+]([O-])C(Cl)(Cl)Cl,rat,30,gc; gavage concentration,104 weeks,0,0.1000000015,0,1
+5653,166,Chlorothalonil,Wilson,1989,JMPR,1990,benzonitrile,fungicide,1897-45-6,"2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile",N#CC1=C(Cl)C(Cl)=C(Cl)C(C#N)=C1Cl,rat,55,fd; food dose,99 weeks,0,1.5,0,3.299999952
+5733,166,Chlorothalonil,Wilson,1985,JMPR,1987,benzonitrile,fungicide,1897-45-6,"2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile",N#CC1=C(Cl)C(Cl)=C(Cl)C(C#N)=C1Cl,rat,60,fc; food concentration,117 weeks,0,0,800,40
+6063,167,Chlorotoluron,Basler,1985,DAR,1999,urea,herbicide,239-592-2,"N'-(3-chloro-4-methylphenyl)-N,N-dimethylurea",CN(C(NC1=CC(Cl)=C(C)C=C1)=O)C,rat,80,fc; food concentration,113 weeks,100,3.700000048,500,0
+930,169,Chlorpropham,Krohmer,1992,JMPR,2000,carbamate,herbicide,101-21-3,1-methylethyl (3-chlorophenyl)carbamate,ClC1=CC=CC(NC(OC(C)C)=O)=C1,rat,60,fd; food dose,104 weeks,0,0,0,30
+931,174,Chlorpyrifos,JMPR,1972,JMPR,1999,organophosphorus,insecticide,2921-88-2,"O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothioate",S=P(OC1=NC(Cl)=C(Cl)C=C1Cl)(OCC)OCC,rat,25,fc; food concentration,104 weeks,0,1,0,10
+5180,174,Chlorpyrifos,Crown,1988,JMPR,1999,organophosphorus,insecticide,2921-88-2,"O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothioate",S=P(OC1=NC(Cl)=C(Cl)C=C1Cl)(OCC)OCC,rat,60,fc; food concentration,104 weeks,5,0.3000000119,100,6
+5185,174,Chlorpyrifos,Young,1988,JMPR,1999,organophosphorus,insecticide,2921-88-2,"O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothioate",S=P(OC1=NC(Cl)=C(Cl)C=C1Cl)(OCC)OCC,rat,60,fd; food dose,104 weeks,0,0.1000000015,0,1
+5652,173,Chlorpyrifos-methyl,Barna-Lloyd,1991,JMPR,1991,organophosphorus,insecticide,5598-13-0,"O,O-dimethyl O-(3,5,6-trichloro-2-pyridinyl)phosphorothioate",ClC1=CC(Cl)=C(OP(OC)(OC)=S)N=C1Cl,rat,60,fc; food concentration,104 weeks,2,0.1000000015,20,1
+932,2034,Chlorsulfuron,Wood,1981,DAR,2007,"urea, triazinylsulfonyl",herbicide,64902-72-3,"2-chloro-N-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]benzenesulfonamide",O=C(NS(C2=CC=CC=C2Cl)(=O)=O)NC1=NC(C)=NC(OC)=N1,rat,80,fc; food concentration,104 weeks,100,4,500,20
+3922,175,Chlorthal-dimethyl,Lucas,1993,DAR,2006,benzoic acid,herbicide,1861-32-1,"2,3,5,6-tetrachloro-1,4-benzenedicarboxylic acid",O=C(C(C(Cl)=C(Cl)C(C(OC)=O)=C1Cl)=C1Cl)OC,rat,70,fd; food dose,104 weeks,0,1,0,10
+6359,2137,Chromafenozide,Kuwahara,1998,DAR,2011,diacylhydrazine,,143807-66-3,"3,4-dihydro-5-methyl-2H-1-benzopyran-6-carboxylic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide",CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C,rat,50,fc; food concentration,104 weeks,1000,35.79999924,4000,145.1000061
+2746,200,Clethodim,Dougherty,1988,DAR,2006,cyclohexanedione oxime,herbicide,99129-21-2,"(E,E)-(+-)-2-[1-[[(3-chloro-2-propenyl)oxy]imino]propyl]-5-[2-(ethylthio)propyl]-3-hydroxy-2-cyclohexen-1-one",O=C1C(/C(CC)=N\OC/C=C/Cl)=C(O)CC(CC(C)SCC)C1,rat,65,fc; food concentration,104 weeks,500,16,2500,86
+934,451,Clodinafop-propargyl,Fankhauser,1992,DAR,2004,2-(4aryloxyphenoxy)propionic acid,herbicide,105512-06-9,propynyl (R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxypropanoate,CC(C(OCC#C)=O)OC1=CC=C(OC2=C(F)C=C(Cl)C=N2)C=C1,rat,80,fc; food concentration,104 weeks,10,0.3199999928,300,10.19999981
+935,2036,Clofencet,,,USA,1997,others,plant growth regulator,129025-54-3,"2-(4-chlorophenyl)-3-ethyl-2,5-dihydro-5-oxo-4-pyridazinecarboxylic acid",ClC(C=C2)=CC=C2N1C(CC)=C(C(O)=O)C(C=N1)=O,rat,,fc; food concentration,104 weeks,1000,47,10000,470
+937,201,Clofentezin,Ginocchio,1985,DAR,2005,tetrazine,acaricide,74115-24-5,"3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine",ClC1=C(C2=NN=C(C3=C(Cl)C=CC=C3)N=N2)C=CC=C1,rat,70,fc; food concentration,104 weeks,40,1.720000029,400,17.29999924
+938,202,Clomazone,Morrow,1984,DAR,2005,others,herbicide,81777-89-1,"2-[(2-chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone",ClC1=CC=CC=C1CN2C(C(C)(C)CO2)=O,rat,120,fc; food concentration,104 weeks,1000,50,2000,100
+939,80,Clopyralid,Barna-Lloyd,1985,DAR,2005,pyridine,herbicide,1702-17-6,"3,6-dichloro-2-pyridinecarboxylic acid",ClC1=CC=C(Cl)C(C(O)=O)=N1,rat,70,fd; food dose,104 weeks,0,15,0,150
+2792,80,Clopyralid,Humiston,1977,DAR,2005,pyridine,herbicide,1702-17-6,"3,6-dichloro-2-pyridinecarboxylic acid",ClC1=CC=C(Cl)C(C(O)=O)=N1,rat,40,fc; food concentration,104 weeks,0,0,0,150
+4548,2161,Cloransulam-methyl,,,USA,1997,triazolopyrimidine sulfonanilide,herbicide,147150-35-4,"3-chloro-2-[[(5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)sulfonyl]amino]benzoic acid",CCOC1=NC(=CC2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3Cl)C(=O)OC)F,rat,,fc; food concentration,104 weeks,0,75,0,325
+5978,302,Clothianidin,Biegel,2000,JMPR,2010,guanidine,insecticide,210880-92-5,[C(E)]-N-[(2-chloro-5-thiazolyl)methyl]-N'-methyl-N''-nitroguanidine,CN/C(NCC1=CN=C(Cl)S1)=N\[N+]([O-])=O,rat,80,fc; food concentration,104 weeks,150,9.699999809,500,32.5
+5654,2066,Coumaphos,Eiben,1988,JMPR,1990,organophosphorus,insecticide,56-72-4,"O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl phosphorothioate",S=P(OCC)(OCC)OC(C=C2)=CC1=C2C(C)=C(Cl)C(O1)=O,rat,50,fc; food concentration,104 weeks,5,0.25,25,1.220000029
+941,203,Cyanamid,Osheroff,1991,DAR,2006,others,herbicide,420-04-2,cyanamide,NC#N,rat,80,gc; gavage concentration,93 weeks,0,1,0,2.5
+6246,2014,Cyantraniliprol,Craig,2011,JMPR,2013,pyrazole,insecticide,736994-63-1,3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide,BrC1=NN(C3=C(Cl)C=CC=N3)C(C(NC2=C(C)C=C(C#N)C=C2C(NC)=O)=O)=C1,rat,70,fc; food concentration,104 weeks,200,8.300000191,2000,84.80000305
+942,319,Cyazofamid,Nakashima,1999,USA,2004,imidazole,fungicide,120116-88-3,"4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide",CC1=CC=C(C2=C(Cl)N=C(C#N)N2S(N(C)C)(=O)=O)C=C1,rat,50,fc; food concentration,104 weeks,5000,171,0,0
+943,344,Cyclanilid,,,USA,1997,anilide,plant growth regulator,113136-77-9,"1-[[(2,4-dichlorophenyl)amino]carbonyl]cyclopropanecarboxylic acid",OC(C2(CC2)C(NC1=C(Cl)C=C(Cl)C=C1)=O)=O,rat,,fc; food concentration,104 weeks,0,8.100000381,0,25.5
+2824,206,Cycloxydim,Kuehborth,1988,DAR,2006,cyclohexanedione oxime,herbicide,101205-02-1,2-[1-(ethoxyimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexene-1-one,O=C1C(/C(CCC)=N\OCC)=C(O)CC(C2CSCCC2)C1,rat,20,wc; water concentration,78 weeks,100,7,400,28
+2825,206,Cycloxydim,Kuehborth,1988,DAR,2006,cyclohexanedione oxime,herbicide,101205-02-1,2-[1-(ethoxyimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexene-1-one,O=C1C(/C(CCC)=N\OCC)=C(O)CC(C2CSCCC2)C1,rat,50,wc; water concentration,104 weeks,0,0,100,6.400000095
+945,935,Cyflufenamid,Cooper,2001,DAR,2006,amide,fungicide,180409-60-3,"(Z)-N-[[(cyclopropylmethoxy)amino][2,3-difluoro-6-(trifluoromethyl)phenyl]methylene]benzeneacetamide",O=C(CC3=CC=CC=C3)N/C(C2=C(F)C(F)=CC=C2C(F)(F)F)=N\OCC1CC1,rat,80,fc; food concentration,104 weeks,100,4.400000095,500,22
+6164,1002,Cyflumetofen,Yoshida,2004,DAR,2011,others,acaricide,400882-07-7,"2-methoxyethyl α-cyano-α-[4-(1,1-dimethylethyl)phenyl]-β-oxo-2-(trifluoromethyl)benzenepropanoate",O=C(C(C2=CC=C(C(C)(C)C)C=C2)(C#N)C(OCCOC)=O)C1=CC=CC=C1C(F)(F)F,rat,30,fc; food concentration,52 weeks,500,18.79999924,1500,0
+6165,1002,Cyflumetofen,Yoshida,2004,DAR,2011,others,acaricide,400882-07-7,"2-methoxyethyl α-cyano-α-[4-(1,1-dimethylethyl)phenyl]-β-oxo-2-(trifluoromethyl)benzenepropanoate",O=C(C(C2=CC=C(C(C)(C)C)C=C2)(C#N)C(OCCOC)=O)C1=CC=CC=C1C(F)(F)F,rat,50,fc; food concentration,104 weeks,500,16.5,1500,0
+4853,208,Cyfluthrin,Suberg,1983,JMPR,2006,pyrethroid,insecticide,68359-37-5,"cyano(4-fluoro-3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(OC(C#N)C2=CC(OC3=CC=CC=C3)=C(F)C=C2)C1C(/C=C(Cl)/Cl)C(C)1C,rat,65,fc; food concentration,104 weeks,150,6.199999809,450,19.20000076
+4854,208,Cyfluthrin,Wahle,1997,JMPR,2006,pyrethroid,insecticide,68359-37-5,"cyano(4-fluoro-3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(OC(C#N)C2=CC(OC3=CC=CC=C3)=C(F)C=C2)C1C(/C=C(Cl)/Cl)C(C)1C,rat,60,fc; food concentration,104 weeks,225,11.60000038,450,22.79999924
+947,179,Cyhalofop-butyl,,,USA,2002,2-(4aryloxyphenoxy)propionic acid,herbicide,122008-85-9,(2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoic acid + estername,N#CC1=CC(F)=C(OC2=CC=C(OC(C)C(OCCCC)=O)C=C2)C=C1,rat,,fc; food concentration,104 weeks,0,0.8230000138,0,3.440000057
+948,209,"Cyhalothrin, lambda-",Pigott,1984,JMPR,2007,pyrethroid,insecticide,91465-08-6,"[1alpha(S*),3alpha(Z)]-(+/-)-cyano-(3-phenoxyphenyl)methyl 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate",CC(C(C1C(OC(C2=CC=CC(OC3=CC=CC=C3)=C2)C#N)=O)/C=C(C(F)(F)F)\Cl)1C,rat,62,fc; food concentration,104 weeks,50,2.299999952,250,12
+949,210,Cyhexatin,Mertens,2004,JMPR,2005,organotin,acaricide,13121-70-5,tricyclohexylhydroxystannane,O[Sn](C2CCCCC2)(C3CCCCC3)C1CCCCC1,rat,70,fc; food concentration,104 weeks,7.5,0.3400000036,30,1.389999986
+4931,210,Cyhexatin,Eisenlord,1970,JMPR,2005,organotin,acaricide,13121-70-5,tricyclohexylhydroxystannane,O[Sn](C2CCCCC2)(C3CCCCC3)C1CCCCC1,rat,45,fd; food dose,104 weeks,0,3,0,6
+4932,210,Cyhexatin,Warner,1977,JMPR,2005,organotin,acaricide,13121-70-5,tricyclohexylhydroxystannane,O[Sn](C2CCCCC2)(C3CCCCC3)C1CCCCC1,rat,50,fd; food dose,104 weeks,0,0,0,1
+951,211,Cymoxanil,Malleshappa,2003,DAR,2007,urea,fungicide,57966-95-7,2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide,O=C(NC(NCC)=O)/C(C#N)=N\OC,rat,50,fc; food concentration,104 weeks,100,4.699999809,500,23.5
+2889,211,Cymoxanil,Cox,1994,DAR,2007,urea,fungicide,57966-95-7,2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide,O=C(NC(NCC)=O)/C(C#N)=N\OC,rat,72,fc; food concentration,104 weeks,100,4.079999924,700,30.29999924
+952,1615,Cypermethrin,,,JMPR,2006,pyrethroid,insecticide,52315-07-8,,CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C,rat,,fc; food concentration,104 weeks,0,7.5,0,50
+2664,1616,"Cypermethrin, zeta-",Forbes,1982,DAR,2006,pyrethroid,insecticide,52315-07-8,"(S)-cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C,rat,52,fc; food concentration,104 weeks,150,7.5,1500,75
+953,214,Cyproconazol,Warren,1988,DAR,2006,triazole,fungicide,94361-06-5,"alpha-(4-chlorophenyl)-alpha-(1-cyclopropylethyl)-1H-1,2,4-triazol-1-ethanol",CC(C(CN2C=NC=N2)(C3=CC=C(C=C3)Cl)O)C1CC1,rat,70,fc; food concentration,104 weeks,50,2.220000029,350,15.53999996
+2954,122,Cyprodinil,Fankhauser,1994,DAR,2005,"pyrimidine, anilino",fungicide,121552-61-2,4-cyclopropyl-6-methyl-N-phenyl-2-pyrimidinamine,CC1=CC(C3CC3)=NC(NC2=CC=CC=C2)=N1,rat,80,fc; food concentration,104 weeks,75,2.700000048,1000,35.59999847
+6717,1613,Cyprosulfamid,Langrand-Lerche,2006,DAR,2012,sulfonamide,herbicide safener,221667-31-8,N-[[4-[(cyclopropylamino)carbonyl]phenyl]sulfonyl]-2-methoxybenzamide,O=C(NC3CC3)C(C=C2)=CC=C2S(NC(C1=CC=CC=C1OC)=O)(=O)=O,rat,70,fc; food concentration,104 weeks,1000,39,4000,0
+2971,215,Cyromazin,Blair,1982,DAR,2007,"1,3,5-triazine",insecticide,66215-27-8,"N-cyclopropyl-1,3,5-triazine-2,4,6-triamine",NC1=NC(N)=NC(NC2CC2)=N1,rat,70,fc; food concentration,104 weeks,300,14.69999981,3000,156
+5710,221,Daminozid,Johnson,1988,JMPR,1989,others,plant growth regulator,1596-84-5,"butanedioic acid mono(2,2-dimethylhydrazide",CN(NC(CCC(O)=O)=O)C,rat,60,fc; food concentration,105 weeks,5000,243,10000,486
+957,961,Dazomet,Kühborth,1989,DAR,2007,dithiocarbamate,fungicide,533-74-4,"tetrahydro-3,5-dimethyl-2H-1,3,5-thiadiazine-2-thione",CN(CN1C)CSC1=S,rat,20,fc; food concentration,104 weeks,20,0.8999999762,80,3.599999905
+2984,961,Dazomet,Kühborth,1989,DAR,2007,dithiocarbamate,fungicide,533-74-4,"tetrahydro-3,5-dimethyl-2H-1,3,5-thiadiazine-2-thione",CN(CN1C)CSC1=S,rat,50,fc; food concentration,104 weeks,20,0.8999999762,80,5.300000191
+958,222,Deltamethrin,Goldenthal,1980,JMPR,2000,pyrethroid,insecticide,52918-63-5,"[1R-[1alpha(S*), 3 alpha]]-cyano (3-phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-dimethylcycropropanecarboxylate",CC1(C)C(/C=C(Br)/Br)C1C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O,rat,90,fc; food concentration,104 weeks,20,1,50,2.5
+5170,222,Deltamethrin,Ryle,1995,JMPR,2000,pyrethroid,insecticide,52918-63-5,"[1R-[1alpha(S*), 3 alpha]]-cyano (3-phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-dimethylcycropropanecarboxylate",CC1(C)C(/C=C(Br)/Br)C1C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O,rat,70,fc; food concentration,104 weeks,25,1.100000024,125,5.400000095
+5694,225,Demeton-S-methyl,Schmidt,1988,JMPR,1989,organophosphorus,insecticide,919-86-8,"S-[2-(ethylthio)ethyl] O,O-dimethyl phosphorothioate",O=P(OC)(OC)SCCSCC,rat,60,fc; food concentration,104 weeks,1,0.05000000075,7,0.349999994
+5706,223,Demeton-S-methyl-sulfon,Suberg,1988,JMPR,1989,organophosphorus,insecticide,17040-19-6,S-[2-(ethylsulfonyl)ethyl],CCS(CCSP(OC)(OC)=O)(=O)=O,rat,60,wc; water concentration,104 weeks,1,0.05999999866,5,0.3000000119
+959,226,Desmedipham,,,UK,1993,"carbamate, bis-",herbicide,13684-56-5,ethyl [3-[[(phenylamino)carbonyl]oxy]phenyl]carbamate,O=C(OCC)NC1=CC=CC(OC(NC2=CC=CC=C2)=O)=C1,rat,,fc; food concentration,104 weeks,0,0,0,3.200000048
+960,231,Diazinon,Kirchner,1991,DAR,2005,organophosphorus,insecticide,333-41-5,"O,O-diethyl O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl]- phosphorothioate",S=P(OCC)(OCC)OC1=NC(C(C)C)=NC(C)=C1,rat,30,fc; food concentration,104 weeks,1.5,0.05999999866,125,5
+3005,231,Diazinon,Angel,,DAR,2005,organophosphorus,insecticide,333-41-5,"O,O-diethyl O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl]- phosphorothioate",S=P(OCC)(OCC)OC1=NC(C(C)C)=NC(C)=C1,rat,50,fc; food concentration,104 weeks,0,0,0,0
+961,232,Dicamba,Goldenthal,1985,DAR,2007,benzoic acid,herbicide,1918-00-9,"3,6-dichloro-2-methoxybenzoic acid",O=C(O)C1=C(OC)C(Cl)=CC=C1Cl,rat,60,fc; food concentration,104 weeks,2500,99,0,0
+3018,233,Dichlobenil,Inoue,1984,DAR,2008,benzonitrile,herbicide,1194-65-6,"2,6-dichlorobenzonitrile",N#CC(C(Cl)=CC=C1)=C1Cl,rat,70,fc; food concentration,104 weeks,0,0,50,3.200000048
+962,235,Dichlorprop-P,Mitsumori,1984,DAR,2004,"alkanoic acid, aryloxy",herbicide,15165-67-0,"(+)-2-(2,4-dichlorophenoxy)propanoic acid",CC(C(O)=O)OC(C=CC(Cl)=C1)=C1Cl,rat,80,fc; food concentration,104 weeks,300,11.01000023,1000,36.5
+3094,236,Dichlorvos,Witherup,1967,DAR,2005,organophosphorus,insecticide,62-73-7,"2,2-dichloroethenyl dimethyl phosphate",O=P(OC)(OC)O/C=C(Cl)\Cl,rat,25,fc; food concentration,104 weeks,4.670000076,0.2300000042,46.70000076,2.299999952
+3096,236,Dichlorvos,NTP,1989,DAR,2005,organophosphorus,insecticide,62-73-7,"2,2-dichloroethenyl dimethyl phosphate",O=P(OC)(OC)O/C=C(Cl)\Cl,rat,50,gc; gavage concentration,104 weeks,0,0,0,0
+4428,237,Diclofop-methyl,Schollmeier,1990,DAR,2009,2-(4aryloxyphenoxy)propionic acid,herbicide,51338-27-3,"Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid",CC(OC1=CC=C(OC2=CC=C(Cl)C=C2Cl)C=C1)C(OC)=O,rat,90,fc; food concentration,104 weeks,2,0.1000000015,6.300000191,0
+4429,237,Diclofop-methyl,Ehling,1996,DAR,2009,2-(4aryloxyphenoxy)propionic acid,herbicide,51338-27-3,"Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid",CC(OC1=CC=C(OC2=CC=C(Cl)C=C2Cl)C=C1)C(OC)=O,rat,80,fc; food concentration,104 weeks,0,0,4.5,0.200000003
+965,238,Dicloran,Lessel,1974,DAR,2006,"aniline, nitro",fungicide,99-30-9,"2,6-dichloro-4-nitrobenzenamine",[O-][N+](C1=CC(Cl)=C(N)C(Cl)=C1)=O,rat,25,no study,104 weeks,0,0,0,0
+3133,238,Dicloran,Woodard,1964,DAR,2006,"aniline, nitro",fungicide,99-30-9,"2,6-dichloro-4-nitrobenzenamine",[O-][N+](C1=CC(Cl)=C(N)C(Cl)=C1)=O,rat,35,fc; food concentration,104 weeks,100,3.369999886,3000,117
+5642,239,Dicofol,Hazelton,1989,JMPR,1992,organochlorine,acaricide,115-32-2,4-chloro-alpha-(4-chlorophenyl)-alpha-(trichloromethyl)benzenemethanol,OC(C1=CC=C(Cl)C=C1)(C2=CC=C(Cl)C=C2)C(Cl)(Cl)Cl,rat,60,fc; food concentration,104 weeks,5,0.2199999988,50,2.200000048
+4419,2158,Didecyldimethylammonium-chlorid,Gill,1991,DAR,2008,,,7173-51-5,,CCCCCCCCCC[N+](C)(C)CCCCCCCCCC.[Cl-],rat,60,fc; food concentration,104 weeks,750,32,1500,64
+3151,242,Diethofencarb,Cox,1989,DAR,2007,"carbamate, phenyl",fungicide,87130-20-9,"1-methylethyl (3,4-diethoxyphenyl)carbamate",CCOC1=CC=C(C=C1OCC)NC(OC(C)C)=O,rat,80,fc; food concentration,104 weeks,1000,42.70000076,5000,220.3000031
+3164,243,Difenoconazol,Cox,1989,DAR,2006,triazole,fungicide,119446-68-3,"1-[2-[4-(4-chlorophenoxy)-2-chlorophenyl]-4-methyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole",CC2COC(O2)(C4=CC=C(C=C4Cl)OC3=CC=C(Cl)C=C3)CN1C=NC=N1,rat,80,fc; food concentration,104 weeks,20,1,500,24.10000038
+3178,245,Diflubenzuron,Hunter,1976,DAR,2006,"urea, benzoyl",insecticide,35367-38-5,"N-[[(4-chlorophenyl)amino]carbonyl]-2,6-difluorobenzamide",O=C(NC(NC2=CC=C(Cl)C=C2)=O)C1=C(F)C=CC=C1F,rat,60,fc; food concentration,104 weeks,160,5.800000191,0,0
+3179,245,Diflubenzuron,Burdock,1984,DAR,2006,"urea, benzoyl",insecticide,35367-38-5,"N-[[(4-chlorophenyl)amino]carbonyl]-2,6-difluorobenzamide",O=C(NC(NC2=CC=C(Cl)C=C2)=O)C1=C(F)C=CC=C1F,rat,50,fc; food concentration,104 weeks,625,31.20000076,2500,125
+969,246,Diflufenican,Holmes,1987,DAR,2006,anilide,herbicide,83164-33-4,"N-(2,4-difluorophenyl)-2-[3-(trifluormethyl)phenoxy]-3-pyridinecarboxamide",O=C(C2=CC=CN=C2OC3=CC=CC(C(F)(F)F)=C3)NC1=CC=C(F)C=C1F,rat,50,fc; food concentration,104 weeks,500,23.27000046,2500,119.5999985
+970,342,Diflufenzopyr,,,USA,1999,"urea, phenyl",herbicide,109293-97-2,"2-[1-[[[(3,5-difluorophenyl)amino]carbonyl]hydrazono]ethyl]-3-pyridinecarboxylic acid",C/C(C1=NC=CC=C1C(O)=O)=N\NC(NC2=CC(F)=CC(F)=C2)=O,rat,,fc; food concentration,104 weeks,5000,236,10000,472
+971,247,Dimefuron,,,UK,1993,oxadiazolone,herbicide,34205-21-5,"N'-[3-chloro-4-[5-(1,1-dimethylethyl)-2-oxo-1,3,4-oxadiazol-3(2H)-yl]phenyl]-N,N-dimethylurea",O=C(NC1=CC(Cl)=C(N2N=C(C(C)(C)C)OC2=O)C=C1)N(C)C,rat,,fc; food concentration,104 weeks,0,7,0,22
+972,248,Dimethachlor,Fankhauser,1995,DAR,2007,chloroacetanilide,herbicide,50563-36-5,"2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide",COCCN(C1=C(C)C=CC=C1C)C(CCl)=O,rat,70,fc; food concentration,104 weeks,300,11.10000038,4000,157
+3197,249,Dimethenamid,Ruckman,1990,DAR,2005,others,herbicide,87674-68-8,"(RS) 2-chloro-N-(2,4-dimethyl-3-thienyl)-N-(2-methoxy-1-methylethyl)acetamide",O=C(N(C1=C(C)SC=C1C)C(C)COC)CCl,rat,70,fc; food concentration,104 weeks,0,0,100,5
+3207,1039,Dimethipin,Goldenthal,1996,DAR,2005,others,plant growth regulator,55290-64-7,"2,3-dihydro-5,6-dimethyl-1,4-dithiin 1,1,4,4-tetraoxide",O=S(C(C)=C(C)S(CC1)(=O)=O)1=O,rat,60,fc; food concentration,104 weeks,40,1.799999952,875,50
+975,250,Dimethoat,Hellwig,1986,DAR,2005,organophosphorus,insecticide,60-51-5,"O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] phosphorodithioate",S=P(OC)(OC)SCC(NC)=O,rat,65,fc; food concentration,104 weeks,1,0.03999999911,5,0.200000003
+3276,250,Dimethoat,Lewerenz,1970,DAR,2005,organophosphorus,insecticide,60-51-5,"O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] phosphorodithioate",S=P(OC)(OC)SCC(NC)=O,rat,30,fc; food concentration,104 weeks,0.1000000015,0,1,0
+3330,66,Dimethomorph,Everett,1990,DAR,2005,morpholine,fungicide,110488-70-5,"4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine",O=C(N2CCOCC2)/C=C(C3=CC=C(Cl)C=C3)/C1=CC=C(OC)C(OC)=C1,rat,20,fc; food concentration,104 weeks,200,9,750,36
+3332,66,Dimethomorph,Everett,1991,DAR,2005,morpholine,fungicide,110488-70-5,"4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine",O=C(N2CCOCC2)/C=C(C3=CC=C(Cl)C=C3)/C1=CC=C(OC)C(OC)=C1,rat,50,fc; food concentration,104 weeks,200,9,750,34
+977,990,Dimoxystrobin,Mellert,2001,DAR,2005,strobilurin,fungicide,149961-52-4,"aE)-2-[(2,5-dimethylphenoxy)methyl]-a-(methoxyimino)-N-methylbenzeneacetamide",CC1=CC=C(C)C=C1OCC2=CC=CC=C2/C(C(NC)=O)=N/OC,rat,20,fc; food concentration,104 weeks,150,7,500,23
+978,252,Dinocap,Maita,1980,JMPR,1998,"benzene, nitro",fungicide,39300-45-3,"(E)-2-(methylheptyl)-4,6-dinitrophenyl 2-butenoate",C/C=C/C(OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1C(C)CCCCCC)=O,rat,80,fc; food concentration,130 weeks,200,6.400000095,2000,64
+979,2037,Dinotefuran,,,USA,2004,guanidine,insecticide,165252-70-0,N-methyl-N′-nitro-N″-[(tetrahydro-3-furanyl)methyl]guanidine,[O][N](N=C(NC)NCC1COCC1)=O,rat,,fc; food concentration,104 weeks,0,99.69999695,0,991
+980,257,Diphenylamin,Botta,1994,DAR,2007,,fungicide,122-39-4,N-phenylbenzenamine,C1(NC2=CC=CC=C2)=CC=CC=C1,rat,60,fc; food concentration,104 weeks,150,7.5,500,25
+981,258,Diquat,Colley,1985,JMPR,2013,bipyridylium,herbicide,2764-72-9,"6,7-dihydrodipyrido[1,2-a:2´,1´-c]pyrazinediium",[N+]12=CC=CC=C1C3=[N+](C=CC=C3)CC2,rat,60,fc; food concentration,104 weeks,15,0.5799999833,75,2.910000086
+5533,258,Diquat,Rogerson,1978,JMPR,1993,bipyridylium,herbicide,2764-72-9,"6,7-dihydrodipyrido[1,2-a:2´,1´-c]pyrazinediium",[N+]12=CC=CC=C1C3=[N+](C=CC=C3)CC2,rat,35,fc; food concentration,104 weeks,25,1.299999952,75,3.900000095
+3368,260,Dithianon,Brown,1991,DAR,2006,quinone,fungicide,3347-22-6,"5,10-dihydro-5,10-dioxonaphtho[2,3-b]-1,4-dithi-in-2,3-dicarbonitrile",O=C(C2=C1C=CC=C2)C(SC(C#N)=C(C#N)S3)=C3C1=O,rat,70,fc; food concentration,104 weeks,20,1,120,6
+3378,261,Diuron,Schmidt,1985,DAR,2005,"urea, phenyl",herbicide,330-54-1,"N'-(3,4-dichlorophenyl)-N,N-dimethylurea",O=C(N(C)C)NC1=CC(Cl)=C(Cl)C=C1,rat,60,fc; food concentration,104 weeks,0,0,25,1.700000048
+984,83,Dodemorph,Vincenti,2004,DAR,2007,morpholine,fungicide,1593-77-7,"4-cyclododecyl-2,6-dimethylmorpholine",CC(C2)OC(C)CN2C1CCCCCCCCCCC1,rat,70,fc; food concentration,104 weeks,833,45,2500,136
+3420,84,Dodin,Dange,1998,DAR,2009,guanidine,fungicide,2439-10-3,dodecylguanidine monoacetate,N=C(N)NCCCCCCCCCCCC.OC(C)=O,rat,60,fc; food concentration,104 weeks,400,20,800,42
+3467,1619,Emamectin,Gerson,1992,DAR,2008,avermectin,insecticide,155569-91-8,(4″R)-4″-deoxy-4″-(methylamino)avermectin B1,CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)NC)OC)OC)C)C.C1=CC=C(C=C1)C(=O)O,rat,20,fd; food dose,52 weeks,0,1,0,2.5
+3472,1619,Emamectin,Lankas,1994,DAR,2008,avermectin,insecticide,155569-91-8,(4″R)-4″-deoxy-4″-(methylamino)avermectin B1,CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)NC)OC)OC)C)C.C1=CC=C(C=C1)C(=O)O,rat,75,fc; food concentration,104 weeks,0,0.25,0,1
+5250,85,Endosulfan,US NCI,1978,JMPR,1998,organochlorine,insecticide,115-29-7,"6,7,8,9,10,10,-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide",O=S3OCC1C(CO3)C2(Cl)C(Cl)=C(Cl)C(Cl)1C(Cl)2Cl,rat,50,fc; food concentration,78 weeks,0,0,220,11
+5251,85,Endosulfan,Ruckman,1989,JMPR,1998,organochlorine,insecticide,115-29-7,"6,7,8,9,10,10,-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide",O=S3OCC1C(CO3)C2(Cl)C(Cl)=C(Cl)C(Cl)1C(Cl)2Cl,rat,50,fc; food concentration,104 weeks,15,0.6000000238,75,2.900000095
+5252,85,Endosulfan,Keller,1959,JMPR,1998,organochlorine,insecticide,115-29-7,"6,7,8,9,10,10,-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide",O=S3OCC1C(CO3)C2(Cl)C(Cl)=C(Cl)C(Cl)1C(Cl)2Cl,rat,25,fc; food concentration,104 weeks,30,1.5,100,5
+986,126,Epoxiconazol,Mellert,1992,DAR,2006,triazole,fungicide,133855-98-8,"rel-1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole",FC1=CC=C(C2(CN4C=NC=N4)C(C3=CC=CC=C3Cl)O2)C=C1,rat,20,fc; food concentration,104 weeks,30,1,150,5
+3491,126,Epoxiconazol,Mellert,1992,DAR,2006,triazole,fungicide,133855-98-8,"rel-1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole",FC1=CC=C(C2(CN4C=NC=N4)C(C3=CC=CC=C3Cl)O2)C=C1,rat,50,fc; food concentration,104 weeks,30,2,150,6
+987,267,Esfenvalerat,,,JMPR,2002,pyrethroid,insecticide,66230-04-4,"[S-(R*,R*)]-cyano(3-phenoxyphenyl)methyl 4-chloro-2-(1-methylethyl)benzeneacetate",N#CC(C2=CC(OC3=CC=CC=C3)=CC=C2)OC(C(C(C)C)C1=CC=C(Cl)C=C1)=O,rat,,fc; food concentration,104 weeks,0,7.5,0,25
+5094,267,Esfenvalerat,Gordon,1978,JMPR,2002,pyrethroid,insecticide,66230-04-4,"[S-(R*,R*)]-cyano(3-phenoxyphenyl)methyl 4-chloro-2-(1-methylethyl)benzeneacetate",N#CC(C2=CC(OC3=CC=CC=C3)=CC=C2)OC(C(C(C)C)C1=CC=C(Cl)C=C1)=O,rat,93,fc; food concentration,104 weeks,250,12,500,0
+5095,267,Esfenvalerat,Arai,1980,JMPR,2002,pyrethroid,insecticide,66230-04-4,"[S-(R*,R*)]-cyano(3-phenoxyphenyl)methyl 4-chloro-2-(1-methylethyl)benzeneacetate",N#CC(C2=CC(OC3=CC=CC=C3)=CC=C2)OC(C(C(C)C)C1=CC=C(Cl)C=C1)=O,rat,80,fc; food concentration,104 weeks,150,7.5,500,0
+988,467,Ethaboxam,,,USA,2006,carboxamide,fungicide,162650-77-3,N-(cyano-2-thienylmethyl)-4-ethyl-2-(ethylamino)-5-thiazolecarboxamide,CCC1=C(C(NC(C2=CC=CS2)C#N)=O)SC(NCC)=N1,rat,,fc; food concentration,104 weeks,100,5.5,300,16.39999962
+989,1033,Ethalfluralin,Adams,1981,DAR,2007,dinitroaniline,herbicide,55283-68-6,"N-ethyl-N-(2-methyl-2-propenyl)-2,6-dinitro-4-(trifluoromethyl)benzenamine",FC(F)(F)C1=CC([N+]([O-])=O)=C(N(CC(C)=C)CC)C([N+]([O-])=O)=C1,rat,30,fc; food concentration,104 weeks,100,4.199999809,250,10.69999981
+3500,1033,Ethalfluralin,Adams,,DAR,2007,dinitroaniline,herbicide,55283-68-6,"N-ethyl-N-(2-methyl-2-propenyl)-2,6-dinitro-4-(trifluoromethyl)benzenamine",FC(F)(F)C1=CC([N+]([O-])=O)=C(N(CC(C)=C)CC)C([N+]([O-])=O)=C1,rat,15,fc; food concentration,52 weeks,250,9.300000191,750,29
+6466,2424,Ethametsulfuron-methyl,Bogdanffy,1991,DAR,2012,"urea, triazinylsulfonyl",herbicide,97780-06-8,"methyl 2-[[[[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]amino]carbonyl]amino]sulfonyl]benzoate",CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC,rat,72,fc; food concentration,104 weeks,500,21,5000,210
+3511,268,Ethephon,VanMiller,1989,DAR,2004,others,plant growth regulator,16672-87-0,(2-chloroethyl)phosphonic acid,O=P(O)(O)CCCl,rat,90,fc; food concentration,104 weeks,300,13,3000,131
+5753,270,Ethion,Morrow,1985,JMPR,1986,organophosphorus,insecticide,563-12-2,"S,S′-methylene bis(O,O-diethyl phosphorodithioate)",S=P(OCC)(OCC)SCSP(OCC)(OCC)=S,rat,80,fc; food concentration,104 weeks,4,0.1800000072,40,1.799999952
+6292,2428,Ethiprole,,,USA,2011,"pyrazole, phenyl",insecticide,181587-01-9,"5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile",CCS(=O)C1=C(N(N=C1C#N)C2=C(C=C(C=C2Cl)C(F)(F)F)Cl)N,rat,,fc; food concentration,104 weeks,20,0.8500000238,75,3.200000048
+3525,273,Ethoprophos,Spicer,1985,DAR,2004,organophosphorus,insecticide,13194-48-4,"O-ethyl S,S-dipropyl phosphorodithioate",O=P(SCCC)(OCC)SCCC,rat,70,fc; food concentration,104 weeks,1,0.05000000075,10,0.5
+3526,273,Ethoprophos,Williams,1992,DAR,2004,organophosphorus,insecticide,13194-48-4,"O-ethyl S,S-dipropyl phosphorodithioate",O=P(SCCC)(OCC)SCCC,rat,80,fc; food concentration,104 weeks,1,0.03999999911,60,2.440000057
+5239,274,Ethoxyquin,,,JMPR,1998,"quinoline, phenoxy",fungicide,91-53-2,"6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoline",CC2(C)C=C(C)C1=CC(OCC)=CC=C1N2,rat,10,fc; food concentration,104 weeks,125,6,250,12
+3541,87,Etofenprox,Green,1986,DAR,2007,pyrethroid,insecticide,80844-07-1,1-[[2-(4-ethoxyphenyl)-2-methylpropoxy]methyl]-3-phenoxybenzene,CCOC1=CC=C(C(C)(C)COCC2=CC(OC3=CC=CC=C3)=CC=C2)C=C1,rat,50,fc; food concentration,108 weeks,100,3.700000048,700,25.5
+5947,347,Etoxazol,Nakashima,1996,JMPR,2010,others,acaricide,153233-91-1,"2-(2,6-difluorophenyl)-4-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydrooxazole",FC1=CC=CC(F)=C1C(OC3)=NC3C2=CC=C(C(C)(C)C)C=C2OCC,rat,60,fd; food dose,104 weeks,0,64,0,0
+5948,347,Etoxazol,Nakashima,2001,JMPR,2010,others,acaricide,153233-91-1,"2-(2,6-difluorophenyl)-4-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydrooxazole",FC1=CC=CC(F)=C1C(OC3)=NC3C2=CC=C(C(C)(C)C)C=C2OCC,rat,65,fc; food concentration,104 weeks,50,1.830000043,5000,187
+993,1043,Etridiazol,Trutter,1988,DAR,2007,others,fungicide,2593-15-9,"5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole",ClC(Cl)(Cl)C1=NSC(OCC)=N1,rat,50,fc; food concentration,104 weeks,0,0,100,5
+994,332,Famoxadon,MacKenzie,1996,JMPR,2003,strobilurin,fungicide,131807-57-3,"5-methyl-5-(4-phenoxyl)-3-phenylamino-2,4-oxazolidinedione",O=C(C(O3)(C)C(C=C2)=CC=C2OC1=CC=CC=C1)N(NC4=CC=CC=C4)C3=O,rat,92,fc; food concentration,104 weeks,200,8.399999619,400,17
+6080,305,Fenamidon,Bigot,1999,JMPR,2013,imidazolinone,fungicide,161326-34-7,"(5S)-3,5-dihydro-5-methyl-2-(methylthio)-5-phenyl-3-(phenylamino)-4H-imidazol-4-one",O=C1N(NC3=CC=CC=C3)C(SC)=NC(C)1C2=CC=CC=C2,rat,70,fc; food concentration,104 weeks,60,2.799999952,150,7.099999905
+3557,276,Fenamiphos,Löser,1972,DAR,2005,organophosphorus,nematicide,22224-92-6,ethyl 3-methyl-4-(methylthio)phenyl (1-methylethyl)phosphoramidate,O=P(OCC)(OC1=CC=C(SC)C(C)=C1)NC(C)C,rat,40,fc; food concentration,104 weeks,10,0.5600000024,30,1.700000048
+3558,276,Fenamiphos,Hayes,1986,DAR,2005,organophosphorus,nematicide,22224-92-6,ethyl 3-methyl-4-(methylthio)phenyl (1-methylethyl)phosphoramidate,O=P(OCC)(OC1=CC=C(SC)C(C)=C1)NC(C)C,rat,70,fc; food concentration,104 weeks,1.700000048,0.1000000015,7.800000191,0.4600000083
+996,277,Fenarimol,Hoffman,1978,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,20,fc; food concentration,78 weeks,50,2.299999952,130,3.599999905
+5343,277,Fenarimol,Hoffman,1978,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,20,fc; food concentration,52 weeks,130,6.5,350,17.5
+5344,277,Fenarimol,Hoffman,1978,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,40,fc; food concentration,104 weeks,0,0,50,2
+5345,277,Fenarimol,Hoffman,1982,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,25,1.200000048,50,2.5
+5346,277,Fenarimol,Hoffman,1985,JMPR,1995,pyrimidine,fungicide,60168-88-9,(+-)-alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol,OC(C2=C(Cl)C=CC=C2)(C3=CN=CN=C3)C1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,50,2,0,0
+997,88,Fenazaquin,Cocke,1992,DAR,2006,others,acaricide,120928-09-8,"4-[[4-(1,1-dimethylethyl)phenyl]ethoxy]quinazoline",CC(C)(C1=CC=C(CCOC2=NC=NC3=CC=CC=C23)C=C1)C,rat,60,fc; food concentration,104 weeks,10,0.4600000083,100,4.5
+3571,136,Fenbuconazol,Wolfe,1990,DAR,2006,triazole,fungicide,114369-43-6,"alpha-[2-(4-chlorophenyl)ethyl]-alpha-phenyl-1H-1,2,4-triazole-1-propanenitrile",ClC(C=C2)=CC=C2CCC(C#N)(CN3C=NC=N3)C1=CC=CC=C1,rat,70,fc; food concentration,104 weeks,80,3,800,31
+999,278,Fenbutatin Oxid,Simpson,1973,DAR,2009,organotin,acaricide,13356-08-6,hexakis(2-methyl-2-phenylpropyl)distannoxane,CC(C1=CC=CC=C1)(C)C[Sn](CC(C)(C2=CC=CC=C2)C)(CC(C)(C3=CC=CC=C3)C)O[Sn](CC(C)(C4=CC=CC=C4)C)(CC(C)(C6=CC=CC=C6)C)CC(C)(C5=CC=CC=C5)C,rat,72,fc; food concentration,104 weeks,100,5,300,15
+1000,348,Fenhexamid,Eiben,1996,JMPR,2005,anilide,fungicide,126833-17-8,"Cyclohexanecarboxamide, N-(2,3-dichliro-4-hydroxyphenyl)-1-ethyl-",CC1(C(NC2=CC=C(O)C(Cl)=C2Cl)=O)CCCCC1,rat,50,fc; food concentration,104 weeks,500,28,5000,292
+3583,281,Fenitrothion,Kadota,1974,DAR,2005,organophosphorus,insecticide,122-14-5,"O,O-dimethyl O-(3-methyl-4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC(C)=C([N+]([O-])=O)C=C1,rat,15,fc; food concentration,93 weeks,10,0.5,0,0
+3584,281,Fenitrothion,Kundzins,1974,DAR,2005,organophosphorus,insecticide,122-14-5,"O,O-dimethyl O-(3-methyl-4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC(C)=C([N+]([O-])=O)C=C1,rat,50,fc; food concentration,104 weeks,10,0.5,30,23.10000038
+3603,995,Fenoxaprop,,,DAR,2006,"(4-aryloxyphenoxy)propionic acid, 2-",herbicide,95617-09-7,2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]propanoic acid,CC(C(O)=O)OC(C=C3)=CC=C3OC2=NC1=CC=C(Cl)C=C1O2,rat,,no study,104 weeks,0,0,0,0
+3605,995,Fenoxaprop,Donaubauer,1985,DAR,2006,"(4-aryloxyphenoxy)propionic acid, 2-",herbicide,95617-09-7,2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]propanoic acid,CC(C(O)=O)OC(C=C3)=CC=C3OC2=NC1=CC=C(Cl)C=C1O2,rat,116,fc; food concentration,120 weeks,30,1.600000024,180,9.399999619
+1003,283,Fenoxycarb,Goodyer,1992,DAR,2009,carbamate,insecticide,72490-01-8,ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate,O=C(OCC)NCCOC1=CC=C(OC2=CC=CC=C2)C=C1,rat,60,fc; food concentration,104 weeks,200,8.100000381,600,24.70000076
+1004,284,Fenpiclonil,,,UK,1993,"pyrrole, phenyl",fungicide,74738-17-3,"4-(2,3-dichlorophenyl)-1H-pyrrole-3-carbonitrile",ClC1=CC=CC(C2=CNC=C2C#N)=C1Cl,rat,,fc; food concentration,104 weeks,0,30,0,120
+1005,285,Fenpropathrin,Warren,1986,JMPR,2012,pyrethroid,insecticide,39515-41-8,"cyano(3-phenoxyphenyl)methyl 2,2,3,3-tetramethylcyclopropanecarboxylate",CC(C(C(C)3C)C(OC(C1=CC=CC(OC2=CC=CC=C2)=C1)C#N)=O)3C,rat,50,fc; food concentration,104 weeks,150,7,450,21
+1006,89,Fenpropidin,Crome,1989,DAR,2006,others,fungicide,67306-00-7,"(+/-)-1-[3-[4-(1,1-dimethylethyl)phenyl{]-2-methylpropyl]piperidine",CC(CC2=CC=C(C(C)(C)C)C=C2)CN1CCCCC1,rat,80,fc; food concentration,104 weeks,50,2.269999981,250,11.82999992
+1007,286,Fenpropimorph,hunter,1982,DAR,2007,morpholine,fungicide,67564-91-4,"cis-4-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine",CC(CC2=CC=C(C(C)(C)C)C=C2)CN1CC(OC(C1)C)C,rat,75,fc; food concentration,104 weeks,10,0.3000000119,50,1.700000048
+6143,2456,Fenpyrazamine,Sommer,2009,DAR,2011,pyrazole,fungicide,473798-59-3,"S-2-propen-1-yl 5-amino-2,3-dihydro-2-(1-methylethyl)-4-(2-methylphenyl)-3-oxo-1H-pyrazole-1-carbothioate",CC1=CC=CC=C1C2=C(N(N(C2=O)C(C)C)C(=O)SCC=C)N,rat,70,fc; food concentration,104 weeks,100,5.289999962,300,0
+1008,287,Fenpyroximate,Aughton,1989,DAR,2006,pyrazole,acaricide,111812-58-9,"(E)-1,1-dimethylethyl 4-[[[[(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino]oxy]methyl]benzoate",O=C(OC(C)(C)C)C1=CC=C(CO/N=C/C2=C(OC3=CC=CC=C3)N(C)N=C2C)C=C1,rat,80,fc; food concentration,104 weeks,25,0.9700000286,75,3
+130,289,Fenthion,Christenson,1990,JMPR,1995,organophosphorus,insecticide,55-38-9,"O,O-dimethyl O-[3-methyl-4-(methylthio)phenyl] phosphorothioate",S=P(OC)(OC)OC1=CC(C)=C(SC)C=C1,rat,50,fc; food concentration,104 weeks,0,0,5,0.200000003
+1009,289,Fenthion,Bomhard,1977,JMPR,1995,organophosphorus,insecticide,55-38-9,"O,O-dimethyl O-[3-methyl-4-(methylthio)phenyl] phosphorothioate",S=P(OC)(OC)OC1=CC(C)=C(SC)C=C1,rat,100,fc; food concentration,104 weeks,3,0.1400000006,15,0.7200000286
+6932,290,Fenvalerat,Arai,1980,JMPR,2012,pyrethroid,insecticide,51630-58-1,cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate,ClC1=CC=C(C(C(C)C)C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O)C=C1,rat,80,fc; food concentration,104 weeks,150,7.5,500,25
+6933,290,Fenvalerat,Gordon,1978,JMPR,2012,pyrethroid,insecticide,51630-58-1,cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate,ClC1=CC=C(C(C(C)C)C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O)C=C1,rat,93,fc; food concentration,78 weeks,250,12.5,500,25
+5330,2013,Ferbam,,,JMPR,1996,dithiocarbamate,fungicide,14484-64-1,"(OC-6-11)-tris(dimethylcarbamodithioato-κS,κS′)iron",CN(C)C(=S)[S-].CN(C)C(=S)[S-].CN(C)C(=S)[S-].[Fe+3],rat,25,fc; food concentration,104 weeks,250,12.5,2500,125
+3644,137,Fipronil,Aughton,1992,DAR,2005,"pyrazole, phenyl",insecticide,120068-37-3,"5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(1R,S)-(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile",ClC(C=C(C=C1Cl)C(F)(F)F)=C1N2N=C(C(S(C(F)(F)F)=O)=C2N)C#N,rat,65,fc; food concentration,104 weeks,0.5,0.01899999939,1.5,0.05900000036
+4604,91,Flazasulfuron,Kitazawa,1995,USA,2007,"urea, sulfonyl",herbicide,104040-78-0,"N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-3-(trifluoromethyl)-2-pyridinesulfonamide",O=S(C1=C(C(F)(F)F)C=CC=N1)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O,rat,50,fc; food concentration,104 weeks,40,1.299999952,400,13.30000019
+3660,949,Flonicamid,Kuwahara,2002,DAR,2005,,insecticide,158062-67-0,N-(cyanomethyl)-4-(trifluoromethyl)-3-pyridinecarboxamide,O=C(NCC#N)C1=CN=CC=C1C(F)(F)F,rat,52,fc; food concentration,104 weeks,200,7.320000172,1000,44.09999847
+4608,350,Florasulam,,,USA,2007,triazolopyrimidine sulfonanilide,herbicide,145701-23-1,"N-(2,6-difluorophenyl)-8-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide",FC1=CC=CC(F)=C1NS(C3=NN2C(OC)=NC=C(F)C2=N3)(=O)=O,rat,60,fd; food dose,104 weeks,0,250,0,500
+1012,291,Fluazifop-butyl,Amyes,1985,DAR,2007,2-(4aryloxyphenoxy)propionic acid,herbicide,79241-46-6,(2R)-2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acid,CC(C(OCCCC)=O)OC1=CC=C(OC2=CC=C(C(F)(F)F)C=N2)C=C1,rat,70,fc; food concentration,104 weeks,10,0.4699999988,80,3.789999962
+1013,65,Fluazinam,Chambers,1993,DAR,2006,"2,6-dinitroaniline",fungicide,79622-59-6,"3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2-pyridinamine",ClC1=C([N+]([O-])=O)C(NC2=NC=C(C(F)(F)F)C=C2Cl)=C([N+]([O-])=O)C=C1C(F)(F)F,rat,25,fc; food concentration,104 weeks,50,1.899999976,100,3.900000095
+3679,65,Fluazinam,Mayfield,1988,DAR,2006,"2,6-dinitroaniline",fungicide,79622-59-6,"3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2-pyridinamine",ClC1=C([N+]([O-])=O)C(NC2=NC=C(C(F)(F)F)C=C2Cl)=C([N+]([O-])=O)C=C1C(F)(F)F,rat,50,fc; food concentration,104 weeks,10,0.3799999952,100,3.819999933
+5923,1005,Flubendiamid,Enomoto,2004,JMPR,2010,amide,insecticide,272451-65-7,"N2-[1,1-dimethyl-2-(methylsulfonyl)ethyl]-3-iodo-N1-[2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]-1,2-benzenedicarboxamide",O=C(NC2=CC=C(C(C(F)(F)F)(F)C(F)(F)F)C=C2C)C1=CC=CC(I)=C1C(NC(C)(C)CS(C)(=O)=O)=O,rat,25,fc; food concentration,52 weeks,50,2,2000,79
+5924,1005,Flubendiamid,Enomoto,2004,JMPR,2010,amide,insecticide,272451-65-7,"N2-[1,1-dimethyl-2-(methylsulfonyl)ethyl]-3-iodo-N1-[2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]-1,2-benzenedicarboxamide",O=C(NC2=CC=C(C(C(F)(F)F)(F)C(F)(F)F)C=C2C)C1=CC=CC(I)=C1C(NC(C)(C)CS(C)(=O)=O)=O,rat,50,fc; food concentration,104 weeks,50,1.700000048,1000,34
+1014,2038,Flucarbazon,,,USA,2000,sulfonamide,herbicide,145026-88-6,"4,5-dihydro-3-methoxy-4-methyl-5-oxo-N-[[2-(trifluoromethoxy)phenyl]sulfonyl]-1H-1,2,4-triazole-1-carboxamide",FC(F)(F)OC(C=CC=C2)=C2S(NC(N1C(N(C)C(OC)=N1)=O)=O)(=O)=O,rat,,fc; food concentration,104 weeks,0,125,0,1000
+5772,293,Flucythrinat,Brewer,1981,JMPR,1985,pyrethroid,insecticide,70124-77-5,cyano(3-phenoxyphenyl)methyl 4-(difluoromethoxy)-alpha-(1-methylethyl)benzeneacetate,CC(C(C3=CC=C(C=C3)OC(F)F)C(OC(C1=CC=CC(OC2=CC=CC=C2)=C1)C#N)=O)C,rat,50,fc; food concentration,104 weeks,30,0,60,0
+3691,138,Fludioxonil,Chang,1993,DAR,2006,"pyrrole, phenyl",fungicide,131341-86-1,"4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile",FC(O3)(F)OC(C3=CC=C2)=C2C1=CNC=C1C#N,rat,80,fc; food concentration,104 weeks,1000,37,3000,113
+6809,2108,Fluensulfon,Kaiser,2011,JMPR,2013,,nematicide,318290-98-1,"5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]thiazole",C1=C(SC(=N1)S(=O)(=O)CCC(=C(F)F)F)Cl,rat,50,fc; food concentration,104 weeks,30,1.399999976,200,9.600000381
+1016,343,Flufenacet,,,USA,1998,anilide,herbicide,142459-58-3,"N-(4-fluorophenyl)-N-(1-methylethyl)-2-{[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy}acetamide",FC(F)(F)C(S2)=NN=C2OCC(N(C(C)C)C1=CC=C(F)C=C1)=O,rat,,fc; food concentration,104 weeks,0,0,25,1.200000048
+3702,294,Flufenoxuron,Esdaile,1990,DAR,2008,"urea, benzoyl",insecticide,101463-69-8,"N-[[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]amino]carbonyl]-2,6-difluorobenzamide",FC1=C(NC(NC(C3=C(F)C=CC=C3F)=O)=O)C=CC(OC2=C(Cl)C=C(C(F)(F)F)C=C2)=C1,rat,30,fc; food concentration,104 weeks,500,22,5000,230
+3703,294,Flufenoxuron,Esdaile,1990,DAR,2008,"urea, benzoyl",insecticide,101463-69-8,"N-[[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]amino]carbonyl]-2,6-difluorobenzamide",FC1=C(NC(NC(C3=C(F)C=CC=C3F)=O)=O)C=CC(OC2=C(Cl)C=C(C(F)(F)F)C=C2)=C1,rat,50,fc; food concentration,104 weeks,500,22,5000,218
+5322,2076,Flumethrin,Bomhard,1987,JMPR,1996,pyrethroid,acaricide,69770-45-2,"cyano(4-fluoro-3-phenoxyphenyl)methyl 3-[2-chloro-2-(4-chlorophenyl)ethenyl]-2,2-dimethylcyclopropanecarboxylate",O=C(OC(C#N)C3=CC(OC4=CC=CC=C4)=C(F)C=C3)C(C(C)2C)C2/C=C(Cl)/C1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,10,0.5,50,2.5
+1018,139,Flumioxazin,Anonymous,1993,DAR,2013,dicarboximide,herbicide,103361-09-7,"2-[7-fluoro-3,4-dihydro-3-oxo-4-(2-propynyl)-3H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione",O=C(C(CCCC4)=C4C3=O)N3C(C(F)=C2)=CC1=C2OCC(N1CC#C)=O,rat,74,fc; food concentration,104 weeks,50,1.799999952,500,18
+1019,1031,Fluometuron,Burdock,1982,DAR,2007,"urea, phenyl",herbicide,2164-17-2,"N,N-dimethyl-N′-[3-(trifluoromethyl)phenyl]urea",FC(F)(F)C1=CC(NC(N(C)C)=O)=CC=C1,rat,60,fc; food concentration,104 weeks,10,0.5529999733,300,17.17300034
+1605,1031,Fluometuron,Hofmann,1966,DAR,2007,"urea, phenyl",herbicide,2164-17-2,"N,N-dimethyl-N′-[3-(trifluoromethyl)phenyl]urea",FC(F)(F)C1=CC(NC(N(C)C)=O)=CC=C1,rat,25,gc; gavage concentration,52 weeks,0,10,0,30
+1020,468,Fluopicolid,Cooper,2003,DAR,2006,pyridine,fungicide,239110-15-7,"2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]benzamide",O=C(C2=C(Cl)C=CC=C2Cl)NCC1=NC=C(C(F)(F)F)C=C1Cl,rat,60,fc; food concentration,104 weeks,200,8.399999619,750,31.5
+6312,2052,Fluopyram,Kennel,2008,EU,2010,,fungicide,658066-35-4,N-[2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl]-2-(trifluoromethyl)benzamide,O=C(NCCC2=NC=C(C(F)(F)F)C=C2Cl)C1=CC=CC=C1C(F)(F)F,rat,70,fc; food concentration,104 weeks,30,1.200000048,150,6
+1021,326,Fluoxastrobin,Schladt,2001,DAR,2005,strobilurin,fungicide,361377-29-9,"(1E)-[2-[[6-(2-chlorophenoxy)-5-fluoro-4-pyrimidinyl]oxy]phenyl](5,6-dihydro-1,4,2-dioxazin-3-yl)methanone O-methyloxime",CO\N=C(C4=NOCCO4)/C(C=CC=C3)=C3OC1=C(F)C(OC2=CC=CC=C2Cl)=NC=N1,rat,50,fc; food concentration,104 weeks,500,35,2500,181
+1022,163,Fluquinconazol,Scowen,1993,DAR,2006,triazole,fungicide,136426-54-5,"3-(2,4-dichlorophenyl)-6-fluoro-2-((1H)-1,2,4-triazol-1-yl)-4(3H)-quinazolinone",O=C2C1=CC(F)=CC=C1N=C(N4N=CN=C4)N2C3=C(Cl)C=C(Cl)C=C3,rat,50,fc; food concentration,104 weeks,10,0.4399999976,100,4.769999981
+1023,296,Flurochloridon,Sprague,1985,DAR,2006,others,herbicide,61213-25-0,3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]-2-pyrrolidinone,FC(F)(C1=CC=CC(N2CC(C(C2=O)Cl)CCl)=C1)F,rat,70,fc; food concentration,104 weeks,100,3.900000095,400,15.69999981
+1024,300,Fluroxypyr,,,USA,1998,"alkanoic acid, aryloxy",herbicide,69377-81-7,"[(4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]acetic acid",OC(COC1=C(C(N)=C(C(F)=N1)Cl)Cl)=O,rat,,fc; food concentration,104 weeks,0,100,0,500
+1025,1035,Flurprimidol,Kehr,1987,DAR,2007,pyrimidine,plant growth regulator,56425-91-3,α-(1-methylethyl)-α-[4-(trifluoromethoxy)phenyl]-5-pyrimidinemethanol,CC(C)C(C2=CN=CN=C2)(O)C1=CC=C(OC(F)(F)F)C=C1,rat,60,fc; food concentration,104 weeks,90,3.599999905,300,9.800000191
+3734,1035,Flurprimidol,Kehr,1987,DAR,2007,pyrimidine,plant growth regulator,56425-91-3,α-(1-methylethyl)-α-[4-(trifluoromethoxy)phenyl]-5-pyrimidinemethanol,CC(C)C(C2=CN=CN=C2)(O)C1=CC=C(OC(F)(F)F)C=C1,rat,30,fc; food concentration,78 weeks,0,0,1000,43.09999847
+1026,978,Flurtamon,,,UK,2000,others,herbicide,96525-23-4,5-[methylamino]-2-phenyl-4-[3-(trifluoromethyl)phenyl]-3(2H)furanone,O=C1C(C3=CC=CC(C(F)(F)F)=C3)=C(NC)OC1C2=CC=CC=C2,rat,,fc; food concentration,104 weeks,0,2.839999914,0,18.39999962
+1027,333,Flusilazol,Pastoor,1986,JMPR,2007,triazole,fungicide,85509-19-9,"1-[[bis(4-fluorophenyl)(methyl)silyl]methyl]-1H-1,2,4-triazole",C[Si](C2=CC=C(C=C2)F)(C3=CC=C(F)C=C3)CN1C=NC=N1,rat,70,fc; food concentration,104 weeks,50,2,250,10
+4820,333,Flusilazol,Keller,1992,JMPR,2007,triazole,fungicide,85509-19-9,"1-[[bis(4-fluorophenyl)(methyl)silyl]methyl]-1H-1,2,4-triazole",C[Si](C2=CC=C(C=C2)F)(C3=CC=C(F)C=C3)CN1C=NC=N1,rat,65,fc; food concentration,104 weeks,0,0,125,5
+1028,2039,Fluthiacet,,,USA,1999,others,herbicide,149253-65-6,"[[2-chloro-4-fluoro-5-[(tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]thio]acetic acid",ClC(C(SCC(O)=O)=C3)=CC(F)=C3\N=C2/SC(N1CCCCN12)=O,rat,,fc; food concentration,104 weeks,50,2.099999905,3000,130
+6895,2019,Flutianil,Anonymous,2009,DAR,2013,others,fungicide,958647-10-4,(2Z)-2-[[2-fluoro-5-(trifluoromethyl)phenyl]thio]-2-[3-(2-methoxyphenyl)-2-thiazolidinylidene]acetonitrile,COC1=C(N3/C(SCC3)=C(C#N)/SC2=CC(C(F)(F)F)=CC=C2F)C=CC=C1,rat,63,fc; food concentration,104 weeks,6000,249,0,0
+2801,94,Flutolanil,Katoh,1982,DAR,2006,anilide,fungicide,66332-96-5,N-[3-(1-methylethoxy)phenyl]-2-(trifluoromethyl)benzamide,O=C(NC2=CC(OC(C)C)=CC=C2)C1=C(C(F)(F)F)C=CC=C1,rat,50,fc; food concentration,104 weeks,200,8.699999809,2000,87
+3742,335,Flutriafol,Milburn,1986,DAR,2006,triazole,fungicide,76674-21-0,"(+-)-alpha-(2-fluorophenyl)-alpha-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol",OC(C2=CC=C(F)C=C2)(C3=C(F)C=CC=C3)CN1C=NC=N1,rat,64,fc; food concentration,104 weeks,20,1.049999952,200,10.19999981
+6177,2109,Fluxapyroxad,Buesen,2009,DAR,2011,pyrazole,fungicide,907204-31-3,"3-(difluoromethyl)-1-methyl-N-(3′,4′,5′-trifluoro[1,1′-biphenyl]-2-yl)-1H-pyrazole-4-carboxamide",CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F,rat,60,fc; food concentration,104 weeks,50,2.099999905,250,0
+3755,338,Folpet,Crown,1989,DAR,2005,N-trihalomethylthio,fungicide,133-07-3,"2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",O=C2N(SC(Cl)(Cl)Cl)C(C1=CC=CC=C12)=O,rat,20,fc; food concentration,104 weeks,250,11.39999962,1500,0
+3756,338,Folpet,Crown,1985,DAR,2005,N-trihalomethylthio,fungicide,133-07-3,"2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",O=C2N(SC(Cl)(Cl)Cl)C(C1=CC=CC=C12)=O,rat,60,fc; food concentration,104 weeks,0,0,500,25
+3757,338,Folpet,Cox,1985,DAR,2005,N-trihalomethylthio,fungicide,133-07-3,"2-[(trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione",O=C2N(SC(Cl)(Cl)Cl)C(C1=CC=CC=C12)=O,rat,50,fc; food concentration,104 weeks,800,40,3200,0
+1032,2046,Fomesafen,,,UK,1995,amide,herbicide,72178-02-0,5-[2-chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitrobenzamide,ClC1=CC(C(F)(F)F)=CC=C1OC2=CC=C([N+]([O-])=O)C(C(NS(C)(=O)=O)=O)=C2,rat,,fc; food concentration,104 weeks,0,0.25,0,5
+4649,316,Foramsulfuron,Higgs,2000,DAR,2001,"urea, sulfonyl",herbicide,173159-57-4,"2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-4-(formylamino)-N,N-dimethylbenzamide",O=CNC1=CC=C(C(N(C)C)=O)C(S(NC(NC2=NC(OC)=CC(OC)=N2)=O)(=O)=O)=C1,rat,70,fc; food concentration,104 weeks,20000,849,0,0
+1033,989,Forchlorfenuron,,,USA,2004,urea,plant growth regulator,68157-60-8,N-(2-chloro-4-pyridinyl)-N′-phenylurea,ClC1=CC(NC(NC2=CC=CC=C2)=O)=CC=N1,rat,,fc; food concentration,104 weeks,150,7,2000,93
+1034,1024,Formetanat,Mallyon,1988,DAR,2005,carbamate,acaricide,23422-53-9,"N,N-dimethyl-N′-[3-[[(methylamino)carbonyl]oxy]phenyl]methanimidamide",CNC(OC1=CC=CC(/N=C/N(C)C)=C1)=O,rat,50,fc; food concentration,104 weeks,50,2.299999952,250,11.5
+1035,351,Fosetyl-Aluminium,Spicer,1981,DAR,2005,organophosphorus,fungicide,39148-24-8,ethyl hydrogen phosphonate,[O-]P(OCC)([H])=O.[O-]P(OCC)([H])=O.[O-]P(OCC)([H])=O.[Al+3],rat,80,fc; food concentration,104 weeks,8000,348,30000,1305
+1036,984,Fosthiazat,,,USA,2004,organophosphorus,nematicide,98886-44-3,O-ethyl S-(1-methylpropyl) (2-oxo-3-thiazolidinyl)phosphonothioate,O=C1N(P(OCC)(SC(C)CC)=O)CCS1,rat,,fc; food concentration,104 weeks,0,0,1,0.3799999952
+1037,354,Fuberidazol,Eiben,1993,DAR,2006,benzimidazole,fungicide,3878-19-1,2-(2-furanyl)-1H-bezimidazole,C2(C3=CC=CO3)=NC1=CC=CC=C1N2,rat,60,fc; food concentration,104 weeks,80,4.599999905,400,23
+1038,2040,Furfural,NTP,1990,USA,2006,others,fungicide,98-01-1,2-furancarboxaldehyde,O=CC1=CC=CO1,rat,,fc; food concentration,104 weeks,0,30,0,60
+3793,303,Glufosinat,Suter,1986,DAR,2004,"amino acid, phosphinico",herbicide,51276-47-2,(+/-)-2-amino-4-(hydroxymethylphosphinyl)butanoic acid,CP(CCC(N)C(O)=O)(O)=O,rat,80,fc; food concentration,130 weeks,500,24.39999962,0,0
+3794,303,Glufosinat,Schmidt,1998,DAR,2004,"amino acid, phosphinico",herbicide,51276-47-2,(+/-)-2-amino-4-(hydroxymethylphosphinyl)butanoic acid,CP(CCC(N)C(O)=O)(O)=O,rat,60,fc; food concentration,104 weeks,1000,57.09999847,5000,228.8999939
+1040,309,Glyphosat,Stout,1990,JMPR,2004,"amino acid, phosphinico",herbicide,1071-83-6,N-(phosphonomethyl)glycine,OC(CNCP(O)(O)=O)=O,rat,60,fd; food dose,104 weeks,8000,362,20000,940
+4976,309,Glyphosat,Milburn,1996,JMPR,2004,"amino acid, phosphinico",herbicide,1071-83-6,N-(phosphonomethyl)glycine,OC(CNCP(O)(O)=O)=O,rat,24,fc; food concentration,52 weeks,2000,141,8000,560
+4977,309,Glyphosat,Atkinson,1993,JMPR,2004,"amino acid, phosphinico",herbicide,1071-83-6,N-(phosphonomethyl)glycine,OC(CNCP(O)(O)=O)=O,rat,85,fd; food dose,104 weeks,0,100,0,300
+4978,309,Glyphosat,Brammer,2001,JMPR,2004,"amino acid, phosphinico",herbicide,1071-83-6,N-(phosphonomethyl)glycine,OC(CNCP(O)(O)=O)=O,rat,52,fc; food concentration,104 weeks,6000,361,20000,1214
+1041,310,Guazatine,Heath,1991,DAR,2007,guanidine,fungicide,108173-90-6,guazatine,NC(NCCCCCCCCNC(N)=N)=N,rat,50,fc; food concentration,104 weeks,150,8,350,18.5
+6347,2104,Halosulfuron-methyl,not given,1992,EU,2011,pyrazole,herbicide,100784-20-1,,CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC,rat,85,fc; food concentration,105 weeks,1000,56.29999924,2500,0
+3844,96,Haloxyfop,Yano,1984,DAR,2009,2-(4aryloxyphenoxy)propionic acid,herbicide,72619-32-0,(+-)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acid,CC(C(O)=O)OC2=CC=C(C=C2)OC1=C(Cl)C=C(C(F)(F)F)C=N1,rat,90,fd; food dose,104 weeks,0,0.06499999762,0,0.1000000015
+5111,314,"HCH, gamma- (Lindan)",Amyes,1990,JMPR,2002,organochlorine,insecticide,58-89-9,,ClC1C(Cl)C(Cl)C(Cl)C(Cl)C1Cl,rat,50,fc; food concentration,52 weeks,10,0.4699999988,100,4.699999809
+5661,70,Hexaconazol,Hext,1988,JMPR,1990,triazole,fungicide,79983-71-4,"(+-)-alpha-butyl-alpha-(2,4-dichlorophenyl)-1H-1,2,4-triazole-1-ethanol",CCCCC(CN1C=NC=N1)(C2=CC=C(C=C2Cl)Cl)O,rat,64,fc; food concentration,104 weeks,10,0.4699999988,100,0
+1043,364,Hexythiazox,Spicer,1984,DAR,2006,carboxamide,acaricide,78587-05-0,trans-5-(4-chlorophenyl--N-cyclohexyl-4-methyl-2-oxo-3-thiazolidinecarboxamide,CC1C(C3=CC=C(C=C3)Cl)SC(N1C(NC2CCCCC2)=O)=O,rat,80,fc; food concentration,104 weeks,60,3.200000048,430,23.10000038
+5811,2501,Hydramethylnon,,,USA,,,,,,CC1(CNC(=NC1)NN=C(C=CC2=CC=C(C=C2)C(F)(F)F)C=CC3=CC=C(C=C3)C(F)(F)F)C,rat,50,fc; food concentration,104 weeks,50,2.400000095,100,4.900000095
+3822,964,Hymexazol,Barker,1992,DAR,2007,,fungicide,10004-44-1,5-methyl-3(2H)-isoxazolone,OC1=NOC(C)=C1,rat,70,fc; food concentration,104 weeks,400,20,2000,99
+3895,365,Imazalil,Lina,1984,DAR,2009,imidazole,fungicide,35554-44-0,"(+/-)-1-[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole",ClC(C=C(Cl)C=C2)=C2C(OCC=C)CN1C=NC=C1,rat,,,78 weeks,0,3.900000095,0,15.89999962
+3896,365,Imazalil,Til,1985,DAR,2009,imidazole,fungicide,35554-44-0,"(+/-)-1-[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole",ClC(C=C(Cl)C=C2)=C2C(OCC=C)CN1C=NC=C1,rat,,,130 weeks,0,3.599999905,0,15
+4664,366,Imazamox,,,USA,1997,imidazolinone,herbicide,114311-32-9,"(+/-)-2-[4,5-dihydro-4-methyl-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5-(methoxymethyl)-3-pyridine carboxylic acid",O=C(O)C1=C(C2=NC(C)(C(C)C)C(N2)=O)N=CC(COC)=C1,rat,,fc; food concentration,104 weeks,20000,1167,0,0
+6818,2819,Imazapic,Fischer,1994,JMPR,2013,imidazolinone,herbicide,104098-48-8,"2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5-methyl-3-pyridinecarboxylic acid",CC1=CN=C(C(=C1)C(=O)O)C2=NC(C(=O)N2)(C)C(C)C,rat,65,fc; food concentration,104 weeks,20000,1029,0,0
+6827,2508,Imazapyr,Daly,1988,JMPR,2013,imidazolinone,herbicide,81334-34-1,"2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-3-pyridinecarboxylic acid",CC(C)C1(C(=O)NC(=N1)C2=C(C=CC=N2)C(=O)O)C,rat,65,fc; food concentration,104 weeks,10000,503,0,0
+1044,2008,Imazaquin,Dickie,1985,DAR,2008,imidazolinone,herbicide,81335-37-7,"2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-3-quinolinecarboxylic acid",O=C(O)C2=C(N=C(C=CC=C3)C3=C2)C(N1)=NC(C)(C(C)C)C1=O,rat,65,fc; food concentration,104 weeks,5000,250,10000,500
+1045,2047,Imazethapyr,,,UK,1996,imidazolinone,herbicide,81335-77-5,"2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5-ethyl-3-pyridinecarboxylic acid",CCC1=CC(C(O)=O)=C(C2=NC(C)(C(C)C)C(N2)=O)N=C1,rat,,fc; food concentration,104 weeks,0,43.5,0,0
+6214,987,Imazosulfuron,Atkinson,1991,DAR,1998,"urea, sulfonyl",herbicide,122548-33-8,"2-chloro-N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]imidazo[1,2-a]pyridine-3-sulfonamide",COC1=NC(NC(NS(C2=C(Cl)N=C3N2C=CC=C3)(=O)=O)=O)=NC(OC)=C1,rat,80,fc; food concentration,104 weeks,2000,106.0999985,20000,0
+3940,98,Imidacloprid,Eiben,1991,DAR,2006,pyridine,insecticide,138261-41-3,1-[(6-chloro-3-pyridinyl)methyl]-N-nitro-2-imidazolidinimine,ClC2=CC=C(C=N2)CN1CCN/C1=N\[N+]([O-])=O,rat,50,fc; food concentration,104 weeks,100,5.699999809,300,24.89999962
+6226,2015,Indaziflam,,,USA,2010,triazine,herbicide,950782-86-2,"N-[(1R,2S)-2,3-dihydro-2,6-dimethyl-1H-inden-1-yl]-6-(1-fluoroethyl)-1,3,5-triazine-2,4-diamine",CC1=CC=C(CC3C)C(C3NC2=NC(N)=NC(C(F)C)=N2)=C1,rat,,fc; food concentration,104 weeks,300,12,3000,0
+1047,355,Indoxacarb,,,JMPR,2005,carbamate,insecticide,173584-44-6,"(S)-methyl 7-chloro-2.5-dihydro-2[[(methoxy-carbonyl) [4-(trifluoromethoxy)phenyl]amino] carbonyl-indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate",ClC1=CC=C(C2=NN(C(N(C(OC)=O)C4=CC=C(OC(F)(F)F)C=C4)=O)COC(C(OC)=O)2C3)C3=C1,rat,72,fc; food concentration,104 weeks,60,2.099999905,125,3.599999905
+6597,311,Iodosulfuron-methyl-Natrium,Wason,1998,DAR,2000,"urea, triazinylsulfonyl",herbicide,144550-36-7,"Methyl-4-iodo-2-[3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-uriedo-sulfonyl)-benzoate, sodium salt",IC1=CC=C(C(OC)=O)C(S([N-]C(NC2=NC(C)=NC(OC)=N2)=O)(=O)=O)=C1.[Na+],rat,70,fc; food concentration,104 weeks,70,2.960000038,700,29.70000076
+6442,2041,Ipconazol,Anonymous,2006,DAR,2011,triazole,fungicide,125225-28-7,"2-[(4-chlorophenyl)methyl]-5-(1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol",OC(C(C(C)C)CC2)(CN3N=CN=C3)C2CC1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,300,13.30000019,0,0
+5332,368,Iprodion,Chambers,1992,JMPR,1995,dicarboximide,fungicide,36734-19-7,"3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide",CC(NC(N1CC(N(C2=CC(Cl)=CC(Cl)=C2)C1=O)=O)=O)C,rat,60,fc; food concentration,52 weeks,150,6,300,12
+5625,368,Iprodion,Hastings,1976,JMPR,1992,dicarboximide,fungicide,36734-19-7,"3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide",CC(NC(N1CC(N(C2=CC(Cl)=CC(Cl)=C2)C1=O)=O)=O)C,rat,60,fc; food concentration,104 weeks,1000,0,0,0
+6562,371,Isoproturon,Heisler,1990,DAR,1999,"urea, phenyl",herbicide,34123-59-6,"N,N-dimethyl-N'-[4-(1-methylethyl)phenyl]urea",CC(C)C1=CC=C(NC(N(C)C)=O)C=C1,rat,50,fc; food concentration,130 weeks,0,0,100,0
+6563,371,Isoproturon,Hunter,1981,DAR,1999,"urea, phenyl",herbicide,34123-59-6,"N,N-dimethyl-N'-[4-(1-methylethyl)phenyl]urea",CC(C)C1=CC=C(NC(N(C)C)=O)C=C1,rat,50,fc; food concentration,104 weeks,80,3.099999905,400,0
+6184,2022,Isopyrazam,Milburn,2008,DAR,2011,pyrazole,fungicide,881685-58-1,"3-(difluoromethyl)-1-methyl-N-[1,2,3,4-tetrahydro-9-(1-methylethyl)-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide",CC(C)C1C2CCC1C3=C2C(NC(C4=CN(C)N=C4C(F)F)=O)=CC=C3,rat,64,fc; food concentration,104 weeks,0,0,100,5.5
+1050,1044,Isoxaben,Gries,1987,DAR,2006,amide,herbicide,82558-50-7,"N-[3-(1-ethyl-1-methylpropyl)-5-isoxazolyl]-2,6-dimethoxybenzamide",COC1=CC=CC(OC)=C1C(NC2=CC(C(CC)(C)CC)=NO2)=O,rat,60,fc; food concentration,104 weeks,1250,51,12500,527
+3965,1044,Isoxaben,Lake,1985,DAR,2006,amide,herbicide,82558-50-7,"N-[3-(1-ethyl-1-methylpropyl)-5-isoxazolyl]-2,6-dimethoxybenzamide",COC1=CC=CC(OC)=C1C(NC2=CC(C(CC)(C)CC)=NO2)=O,rat,30,fc; food concentration,52 weeks,1250,58,12500,600
+4701,360,Isoxaflutol,Chase,1995,JMPR,2013,triketone,herbicide,141112-29-0,(5-cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone,FC(F)(F)C(C=C3S(C)(=O)=O)=CC=C3C(C1=C(C2CC2)ON=C1)=O,rat,75,fd; food dose,104 weeks,0,2,0,20
+4717,2165,Kasugamycin,,,USA,2005,,bactericide,6980-18-3,"3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-D-chiro-inositol",CC1C(CC(C(O1)OC2C(C(C(C(C2O)O)O)O)O)N)N=C(C(=O)O)N,rat,,fc; food concentration,104 weeks,300,11.30000019,3000,116
+5890,148,Kresoxim-methyl,Kamp,2008,DAR,2010,strobilurin,fungicide,143390-89-0,(E)-alpha-(methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetic acid methyl ester,COC(/C(C(C=CC=C2)=C2COC1=C(C)C=CC=C1)=N/OC)=O,rat,,fc; food concentration,104 weeks,0,0,16000,752.0999756
+5891,148,Kresoxim-methyl,Mellert,1994,DAR,2010,strobilurin,fungicide,143390-89-0,(E)-alpha-(methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetic acid methyl ester,COC(/C(C(C=CC=C2)=C2COC1=C(C)C=CC=C1)=N/OC)=O,rat,70,fc; food concentration,104 weeks,800,36,8000,375
+3970,373,Lenacil,Thirlwell,2002,DAR,2008,uracil,herbicide,2164-08-1,"3-cyclohexyl-6,7-dihydro-1H-cyclopentapyrimidine-2,4(3H,5H)-dione",O=C2NC1=C(C(N2C3CCCCC3)=O)CCC1,rat,20,fc; food concentration,52 weeks,2500,139.1000061,25000,0
+3971,373,Lenacil,Thirlwell,2002,DAR,2008,uracil,herbicide,2164-08-1,"3-cyclohexyl-6,7-dihydro-1H-cyclopentapyrimidine-2,4(3H,5H)-dione",O=C2NC1=C(C(N2C3CCCCC3)=O)CCC1,rat,50,fc; food concentration,104 weeks,250,12,2500,118
+1052,374,Linuron,,,USA,1995,urea,herbicide,330-55-2,"N'-(3,4-dichlorophenyl)-1-methoxy-1-methylurea",O=C(NC1=CC(Cl)=C(Cl)C=C1)N(C)OC,rat,,fc; food concentration,104 weeks,50,2.5,125,6.25
+6381,374,Linuron,,,USA,1995,urea,herbicide,330-55-2,"N'-(3,4-dichlorophenyl)-1-methoxy-1-methylurea",O=C(NC1=CC(Cl)=C(Cl)C=C1)N(C)OC,rat,,fc; food concentration,104 weeks,125,6.25,625,31.25
+6382,374,Linuron,,,USA,1995,urea,herbicide,330-55-2,"N'-(3,4-dichlorophenyl)-1-methoxy-1-methylurea",O=C(NC1=CC(Cl)=C(Cl)C=C1)N(C)OC,rat,,fc; food concentration,78 weeks,25,1.25,125,6.25
+1053,119,Lufenuron,Bachmann,1993,DAR,2007,"urea, benzoyl",insecticide,103055-07-8,"N-[[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenil]amino]carbonyl]-2,6-difluorobenzamide",O=C(NC(NC2=CC(Cl)=C(OC(F)(F)C(F)C(F)(F)F)C=C2Cl)=O)C1=C(F)C=CC=C1F,rat,80,fc; food concentration,104 weeks,50,1.929999948,500,20.39999962
+4005,377,Malathion,Daly,1996,DAR,2004,organophosphorus,insecticide,121-75-5,diethyl [(dimethoxyphosphinothioyl)thio]butanedioate,O=C(OCC)C(CC(OCC)=O)SP(OC)(OC)=S,rat,90,fc; food concentration,104 weeks,50,3,500,29
+4007,377,Malathion,Rucci,1980,DAR,2004,organophosphorus,insecticide,121-75-5,diethyl [(dimethoxyphosphinothioyl)thio]butanedioate,O=C(OCC)C(CC(OCC)=O)SP(OC)(OC)=S,rat,50,fc; food concentration,104 weeks,100,17,1000,143
+4398,99,Maleinsäurehydrazid,Van der Heijden,1981,DAR,1997,others,plant growth regulator,10071-13-3;123-33-1,"1,2-dihydro-3,6-pyridazinedione",OC1=CC=C(O)N=N1,rat,55,fc; food concentration,120 weeks,0,0,10000,0
+4399,99,Maleinsäurehydrazid,Perry,1991,DAR,1997,others,plant growth regulator,10071-13-3;123-33-1,"1,2-dihydro-3,6-pyridazinedione",OC1=CC=C(O)N=N1,rat,70,fd; food dose,104 weeks,0,25,0,500
+1056,378,Mancozeb,Stadler,1990,JMPR,1993,dithiocarbamate,fungicide,8018-01-7,"[[1,2-ethanediylbis[carbamodithioato]](2-)]manganese mixture with [[1,2-ethanediylbis[carbamodithioato]](2-)]zinc",S=C1S[Mn+2]SC(NCCN1)=S,rat,72,fc; food concentration,104 weeks,125,4.800000191,750,28.79999924
+5519,378,Mancozeb,Hooks,1992,JMPR,1993,dithiocarbamate,fungicide,8018-01-7,"[[1,2-ethanediylbis[carbamodithioato]](2-)]manganese mixture with [[1,2-ethanediylbis[carbamodithioato]](2-)]zinc",S=C1S[Mn+2]SC(NCCN1)=S,rat,70,fc; food concentration,104 weeks,100,4,400,0
+1057,946,Mandipropamid,Pinto,2005,DAR,2008,amide,fungicide,374726-62-2,4-chloro-N-[2-[3-methoxy-4-(2-propynyloxy)phenyl]ethyl]-a-(2-propynyloxy)benzeneacetamide,C#CCOC(C(NCCC2=CC=C(OCC#C)C(OC)=C2)=O)C1=CC=C(Cl)C=C1,rat,64,fc; food concentration,104 weeks,50,3,250,15.19999981
+5510,379,Maneb,Leuschner,1979,JMPR,1993,dithiocarbamate,fungicide,12427-38-2,"[1,2-ethanediylbis[carbamodithioato](2-)]manganese",[S]C(NCCNC(S[Mn])=S)=S,rat,90,fc; food concentration,130 weeks,300,20,1000,67
+7039,375,MCPA,Kirsch,1988,JMPR,2012,"alkanoic acid, aryloxy",herbicide,94-74-6,(4-chloro-2-methylphenoxy)acetic acid,O=C(O)COC(C=CC(Cl)=C1)=C1C,rat,50,fc; food concentration,104 weeks,80,4.800000191,320,19
+1058,381,Mecoprop,,,UK,1994,"propionic acid, aryloxyphenoxy",herbicide,7085-19-0,(+/-)-2-(4-chloro-2-methylphenoxy)propanoic acid,O=C(O)C(C)OC1=C(C)C=C(Cl)C=C1,rat,,fc; food concentration,104 weeks,0,1.100000024,0,5.5
+4036,325,Mepiquat chlorid,Mellert,1994,DAR,2006,quaternary ammonium,plant growth regulator,24307-26-4,"1,1-dimethylpiperidinium chloride",C[N+]1(C)CCCCC1.[Cl-],rat,20,fc; food concentration,104 weeks,2316,106,5790,268
+4038,325,Mepiquat chlorid,Leuschner,1979,DAR,2006,quaternary ammonium,plant growth regulator,24307-26-4,"1,1-dimethylpiperidinium chloride",C[N+]1(C)CCCCC1.[Cl-],rat,100,fc; food concentration,104 weeks,3000,186,9000,684
+4052,1612,Meptyldinocap,Ferguson,1999,DAR,2008,dinitrophenol,fungicide,131-72-6,"2-(1-methylheptyl)-4,6-dinitrophenyl (2E)-2-butenoate",CC(CCCCCC)C1=C(OC(/C=C\C)=O)C([N+]([O-])=O)=CC([N+]([O-])=O)=C1,rat,20,fc; food concentration,52 weeks,200,11.5,2000,120.8000031
+4053,1612,Meptyldinocap,Maita,1980,DAR,2008,dinitrophenol,fungicide,131-72-6,"2-(1-methylheptyl)-4,6-dinitrophenyl (2E)-2-butenoate",CC(CCCCCC)C1=C(OC(/C=C\C)=O)C([N+]([O-])=O)=CC([N+]([O-])=O)=C1,rat,80,fc; food concentration,130 weeks,200,6.400000095,2000,71
+4733,370,Mesosulfuron-methyl,,,USA,2004,"urea, sulfonyl",herbicide,208465-21-8,"methyl, 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-4-[[(methylsulfonyl)amino]methyl]benzoic acid",O=S(NCC1=CC=C(C(OC)=O)C(S(NC(NC2=NC(OC)=CC(OC)=N2)=O)(=O)=O)=C1)(C)=O,rat,,fc; food concentration,104 weeks,0,764,0,0
+6471,307,Mesotrione,Brammer,1997,DAR,2004,triketone,herbicide,104206-82-8,"2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione",O=C(C2=CC=C(S(=O)(C)=O)C=C2[N+]([O-])=O)C1C(CCCC1=O)=O,rat,64,fc; food concentration,104 weeks,0,0,7.5,0.4799999893
+6765,1008,Metaflumizon,Kelly,2003,DAR,2009,urea,insecticide,139968-49-3,2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]hydrazinecarboxamide,O=C(NC3=CC=C(OC(F)(F)F)C=C3)N/N=C(C2=CC=C(C(F)(F)F)C=C2)/CC1=CC=C(C#N)C=C1,rat,80,gd; gavage dose,104 weeks,0,60,0,200
+5126,383,Metalaxyl,Ahby,1980,JMPR,2002,arylalanine,fungicide,57837-19-1,"methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-DL-alaninate",CC1=C(N(C(C(OC)=O)C)C(COC)=O)C(C)=CC=C1,rat,80,fc; food concentration,104 weeks,1250,43,0,0
+4063,102,Metaldehyd,Gill,1992,DAR,2006,others,molluscicide,108-62-3,"2,4,6,8-tetramethyl-1,3,5,7-tetraoxacyclo-octane",CC1OC(C)OC(C)OC(C)O1,rat,60,fc; food concentration,104 weeks,50,2,1000,44
+4064,102,Metaldehyd,Verschuuren,1975,DAR,2006,others,molluscicide,108-62-3,"2,4,6,8-tetramethyl-1,3,5,7-tetraoxacyclo-octane",CC1OC(C)OC(C)OC(C)O1,rat,25,fc; food concentration,108 weeks,0,0,200,0
+1061,1037,Metam,Rattray,1994,DAR,2007,dithiocarbamate,fungicide,144-54-7,methylcarbamodithioic acid,S=C(S)NC,rat,64,wc; water concentration,104 weeks,19,1.5,56,4.300000191
+1062,384,Metamitron,Leser,1998,DAR,2007,"1,2,4-triazinone",herbicide,41394-05-2,"4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one",O=C1C(C2=CC=CC=C2)=NN=C(C)N1N,rat,60,fc; food concentration,104 weeks,100,4.900000095,400,19.5
+4082,384,Metamitron,Bomhard,1978,DAR,2007,"1,2,4-triazinone",herbicide,41394-05-2,"4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one",O=C1C(C2=CC=CC=C2)=NN=C(C)N1N,rat,50,fc; food concentration,104 weeks,250,13.30000019,1250,74.59999847
+1063,385,Metazachlor,Krishnappa,2002,DAR,2005,imidazole,herbicide,67129-08-2,"2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide",O=C(N(C2=C(C)C=CC=C2C)CN1N=CC=C1)CCl,rat,80,fc; food concentration,104 weeks,200,8.5,2000,87
+4098,385,Metazachlor,Hunter,1983,DAR,2005,imidazole,herbicide,67129-08-2,"2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide",O=C(N(C2=C(C)C=CC=C2C)CN1N=CC=C1)CCl,rat,75,fc; food concentration,113 weeks,0,0,500,17.60000038
+4099,385,Metazachlor,Hunter,1983,DAR,2005,imidazole,herbicide,67129-08-2,"2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide",O=C(N(C2=C(C)C=CC=C2C)CN1N=CC=C1)CCl,rat,75,fc; food concentration,104 weeks,100,3.200000048,0,0
+1064,140,Metconazol,Taupin,1992,DAR,2005,triazole,fungicide,125116-23-6,"5-[(4-chlorophenyl)methyl]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol",OC1(CN3C=NC=N3)C(C)(C)CCC1CC2=CC=C(Cl)C=C2,rat,30,fc; food concentration,104 weeks,100,4.300000191,300,13.10000038
+4136,140,Metconazol,Taupin,1992,DAR,2005,triazole,fungicide,125116-23-6,"5-[(4-chlorophenyl)methyl]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol",OC1(CN3C=NC=N3)C(C)(C)CCC1CC2=CC=C(Cl)C=C2,rat,50,fc; food concentration,104 weeks,100,4.599999905,300,13.80000019
+1065,388,Methamidophos,Hayes,1984,JMPR,2002,organophosphorus,insecticide,10265-92-6,"O,S-dimethyl phosphoramidothioate",O=P(SC)(OC)N,rat,50,fc; food concentration,104 weeks,2,0.1000000015,6,0.2899999917
+1066,390,Methidathion,Johnston,1967,JMPR,1992,organophosphorus,insecticide,950-37-8,"S-[(5-methoxy-2-oxo-1,2,4-thiadiazol-3(2H)-yl)methyl] O,O-dimethyl phosphorodithioate",S=P(OC)(OC)SCN1C(SC(OC)=N1)=O,rat,25,fc; food concentration,104 weeks,4,0.1599999964,16,0.6399999857
+5611,390,Methidathion,Yau,1986,JMPR,1992,organophosphorus,insecticide,950-37-8,"S-[(5-methoxy-2-oxo-1,2,4-thiadiazol-3(2H)-yl)methyl] O,O-dimethyl phosphorodithioate",S=P(OC)(OC)SCN1C(SC(OC)=N1)=O,rat,65,fc; food concentration,104 weeks,4,0.1599999964,40,1.720000029
+1067,391,Methiocarb,Krötlinger,1981,DAR,2005,carbamate,insecticide,2032-65-7,"3,5-dimethyl-4-(methylthio)phenyl methylcarbamate",O=C(OC1=CC(C)=C(SC)C(C)=C1)NC,rat,60,fc; food concentration,104 weeks,200,9.300000191,600,28
+1068,392,Methomyl,Kaplan,1981,DAR,2004,"carbamate, oxime",insecticide,16752-77-5,methyl N-[[(methylamino)carbonyl]oxy]ethanimidothioate,CNC(O/N=C(C)\SC)=O,rat,80,fc; food concentration,104 weeks,100,4.800000191,400,19.20000076
+5145,2079,Methopren,Wazeter,1975,JMPR,2001,others,insecticide,40596-69-8,"1-methylethyl (2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate",CC(C)OC(/C=C(C)/C=C/CC(C)CCCC(C)(C)OC)=O,rat,50,fc; food concentration,104 weeks,1000,50,5000,250
+1069,356,Methoxyfenozid,Anderson,1998,JMPR,2003,others,insecticide,161050-58-4,"Benzoic acid, 3-methoxy-2-methyl-, 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl) hydrazide",CC1=C(OC)C=CC=C1C(NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O)=O,rat,70,fc; food concentration,104 weeks,200,10,8000,411
+4159,103,Methylbromid,Mertens,1997,DAR,2006,others,insecticide,74-83-9,bromomethane,BrC([H])([H])[H],rat,70,cc; capsule concentration,104 weeks,50,2.200000048,250,11
+4160,103,Methylbromid,Mitsumori,1990,DAR,2006,others,insecticide,74-83-9,bromomethane,BrC([H])([H])[H],rat,60,fc; food concentration,104 weeks,200,7,500,17
+1070,395,Metiram,Hunter,1981,JMPR,1993,"dithiocarbamate, alkylenebis",fungicide,9006-42-2,metiram (composition not specified),C(CNC(=S)[S-])NC(=S)[S-].[Zn+2],rat,50,fc; food concentration,104 weeks,80,3.099999905,320,12.30000019
+6875,396,Metobromuron,Kirsch,1986,DAR,2012,"urea, phenyl",herbicide,3060-89-7,N'-(4-bromophenyl)-N-methoxy-N-methylurea,BrC1=CC=C(NC(N(C)OC)=O)C=C1,rat,60,fc; food concentration,104 weeks,50,3.099999905,150,3.720000029
+1071,2042,Metofluthrin,,,USA,2006,,,240494-70-6,"[2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl 2,2-dimethyl-3-(1-propenyl)cyclopropanecarboxylate",COCC1=C(F)C(F)=C(COC(C2C(/C=C/C)C(C)2C)=O)C(F)=C1F,rat,,fc; food concentration,104 weeks,200,8.199999809,900,38.09999847
+6395,397,"Metolachlor, S-",Sorenson,1983,USA,1995,chloroacetanilide,herbicide,87392-12-9,(S)-2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-metylethyl)acetamide,O=C(N(C1=C(C)C=CC=C1CC)C(C)COC)CCl,rat,60,fc; food concentration,104 weeks,300,15,3000,150
+1072,141,Metosulam,Zempel,1992,DAR,2009,triazolopyrimidine sulfonanilide,herbicide,139528-85-1,"N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide",CC1=C(Cl)C(NS(C2=NN3C(N=C(OC)C=C3OC)=N2)(=O)=O)=C(Cl)C=C1,rat,60,fd; food dose,104 weeks,0,5,0,30
+1073,947,Metrafenon,Kelly,2002,DAR,2005,benzophenone,fungicide,220899-03-6,"(3-bromo-6-methoxy-2-methylphenyl)(2,3,4-trimethoxy-6-methylphenyl)methanone",BrC1=C(C)C(C(C2=C(C)C=C(OC)C(OC)=C2OC)=O)=C(OC)C=C1,rat,65,fc; food concentration,104 weeks,500,25,5000,260
+1074,400,Metribuzin,Christenson,1993,DAR,2005,"1,2,4-triazinone",herbicide,21087-64-9,"4-amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one",O=C1C(C(C)(C)C)=NN=C(SC)N1N,rat,50,fc; food concentration,104 weeks,30,1.299999952,300,13
+4183,400,Metribuzin,Löser,1974,DAR,2005,"1,2,4-triazinone",herbicide,21087-64-9,"4-amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one",O=C1C(C(C)(C)C)=NN=C(SC)N1N,rat,40,fc; food concentration,104 weeks,100,5.300000191,300,14.39999962
+4184,400,Metribuzin,Deshmukh,2000,DAR,2005,"1,2,4-triazinone",herbicide,21087-64-9,"4-amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one",O=C1C(C(C)(C)C)=NN=C(SC)N1N,rat,80,wc; water concentration,104 weeks,20,1.600000024,100,0
+7060,401,Metsulfuron-methyl,Hamada,1985,DAR,2013,"urea, triazinylsulfonyl",herbicide,74223-64-6,"methyl-2-[[[[(4-methoxy-6-methyl-1,3,5-triazin-zyl)-amino]carbonyl]amino]sulfonil]benzoate",O=C(OC)C1=CC=CC=C1S(NC(NC2=NC(C)=NC(OC)=N2)=O)(=O)=O,rat,90,fc; food concentration,104 weeks,500,23,5000,119
+1075,152,Mevinphos,Plutnick,1994,JMPR,1996,organophosphorus,insecticide,7786-34-7,methyl 3-[(dimethoxyphosphinyl)oxy]-2-butenoate,O=P(OC)(OC)O/C(C)=C/C(OC)=O,rat,80,gd; gavage dose,104 weeks,0,0.02500000037,0,0.349999994
+6135,934,Milbemectin,Matsunuma,1989,DAR,,avermectin,insecticide,51596-10-2,"(6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-ethylmilbemycin B mixture with (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-methylmilbemycin B",CC1CCC2(CC3CC(O2)CC=C(CC(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)C)OC1C,rat,65,fc; food concentration,104 weeks,15,0.6999999881,150,6.800000191
+1076,405,Monolinuron,,,UK,1995,"urea, phenyl",herbicide,1746-81-2,N'-(4-chlorophenyl)-N-methoxy-N-methylurea,O=C(N(OC)C)NC1=CC=C(Cl)C=C1,rat,,fc; food concentration,104 weeks,0,0.5,0,2
+2359,406,Myclobutanil,Shellenberger,1986,DAR,2006,triazole,fungicide,88671-89-0,"alpha-butyl-alpha-(4-chlorophenyl)-1H-1,2,4-triazole-1-propanenitrile",CCCCC(C#N)(C2=CC=C(C=C2)Cl)CN1C=NC=N1,rat,54,fc; food concentration,104 weeks,35,2.5,140,9.899999619
+4195,406,Myclobutanil,Wolfe,1993,DAR,2006,triazole,fungicide,88671-89-0,"alpha-butyl-alpha-(4-chlorophenyl)-1H-1,2,4-triazole-1-propanenitrile",CCCCC(C#N)(C2=CC=C(C=C2)Cl)CN1C=NC=N1,rat,60,fc; food concentration,104 weeks,0,0,2500,106
+1078,411,Napropamid,Pettersen,1991,DAR,2006,alkanamide,herbicide,15299-99-7,"N,N-diethyl-2(1-naphthalenyloxy)propanamide",O=C(N(CC)CC)C(OC1=CC=CC2=C1C=CC=C2)C,rat,60,fd; food dose,104 weeks,250,10.47999954,1100,47.56000137
+4199,411,Napropamid,Trutter,1978,DAR,2006,alkanamide,herbicide,15299-99-7,"N,N-diethyl-2(1-naphthalenyloxy)propanamide",O=C(N(CC)CC)C(OC1=CC=CC2=C1C=CC=C2)C,rat,60,fd; food dose,104 weeks,0,30,0,100
+1079,64,Nicosulfuron,Broadmeadow,1991,DAR,2006,"urea, sulfonyl",herbicide,111991-09-4,"2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-N,N-dimethyl-3-pyridinecarboxamide",O=S(C1=C(C(N(C)C)=O)C=CC=N1)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O,rat,60,fc; food concentration,104 weeks,5000,199,50000,2088
+4218,142,Novaluron,Thirlwell,2000,DAR,2008,"urea, benzoyl",insecticide,116714-46-6,"(+-)-N-[[[3-chkloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy]phenyl]amino]carbonyl]-2,6-difluorobenzamide",FC(C=CC=C2F)=C2C(NC(NC1=CC=C(OC(F)(F)C(F)OC(F)(F)F)C(Cl)=C1)=O)=O,rat,72,fc; food concentration,104 weeks,25,1.100000024,700,30.60000038
+4446,439,Orthophenylphenol,Hodge,1952,DAR,2008,others,fungicide,90-43-7,o-hydroxybiphenyl,OC1=C(C2=CC=CC=C2)C=CC=C1,rat,25,fc; food concentration,104 weeks,2000,100,20000,1000
+4447,439,Orthophenylphenol,Washle,1996,DAR,2008,others,fungicide,90-43-7,o-hydroxybiphenyl,OC1=C(C2=CC=CC=C2)C=CC=C1,rat,70,fc; food concentration,104 weeks,800,39,4000,200
+4448,439,Orthophenylphenol,Hiraga,1984,DAR,2008,others,fungicide,90-43-7,o-hydroxybiphenyl,OC1=C(C2=CC=CC=C2)C=CC=C1,rat,20,fc; food concentration,93 weeks,6250,269,12500,531
+6734,1009,Orthosulfamuron,,2004,DAR,2012,"urea, sulfonyl",herbicide,213464-77-8,"2-[[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]amino]-N,N-dimethylbenzamide",CN(C)C(C(C=CC=C2)=C2NS(NC(NC1=NC(OC)=CC(OC)=N1)=O)(=O)=O)=O,rat,50,fd; food dose,104 weeks,0,5,0,500
+4233,421,Oryzalin,Kitchen,1978,DAR,2009,"2,6-dinitroaniline",herbicide,19044-88-3,"4-(dipropylamino)-3,5-dinitrobenzenesulfonamide",NS(C1=CC([N+]([O-])=O)=C(N(CCC)CCC)C([N+]([O-])=O)=C1)(=O)=O,rat,15,fc; food concentration,52 weeks,0,0,300,14
+4234,421,Oryzalin,Carter,1980,DAR,2009,"2,6-dinitroaniline",herbicide,19044-88-3,"4-(dipropylamino)-3,5-dinitrobenzenesulfonamide",NS(C1=CC([N+]([O-])=O)=C(N(CCC)CCC)C([N+]([O-])=O)=C1)(=O)=O,rat,30,fc; food concentration,104 weeks,300,12,900,36
+6469,983,Oxadiargyl,Aughton,1997,APPLICANT,2012,oxadiazolone,herbicide,39807-15-3,"3-[2,4-dichloro-5-(2-propynyloxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one",CC(C)(C)C(OC2=O)=NN2C1=CC(OCC#C)=C(Cl)C=C1Cl,rat,50,,104 weeks,0,0,0,0
+1081,999,Oxadiazon,Shirasu,1987,DAR,2007,oxadiazolone,herbicide,19666-30-9,"3-[2,4-dichloro-5-(1-methylethoxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one",O=C(OC(C(C)(C)C)=N2)N2C1=CC(OC(C)C)=C(Cl)C=C1Cl,rat,80,fc; food concentration,104 weeks,10,0.3600000143,100,3.599999905
+4253,424,Oxamyl,Malley,1991,DAR,2004,"carbamate, oxime",insecticide,23135-22-0,methyl 2-(dimethylamino)-N-[[(methylamino)carbonyl]oxy]-2-oxoethanimidothioate,CNC(ON=C(SC)C(N(C)C)=O)=O,rat,62,fc; food concentration,104 weeks,50,1.970000029,100,4.190000057
+4255,424,Oxamyl,Sherman,1972,DAR,2004,"carbamate, oxime",insecticide,23135-22-0,methyl 2-(dimethylamino)-N-[[(methylamino)carbonyl]oxy]-2-oxoethanimidothioate,CNC(ON=C(SC)C(N(C)C)=O)=O,rat,36,fc; food concentration,104 weeks,50,2.299999952,100,4.900000095
+6116,124,Oxychinolin,NTP,1981,DAR,2011,others,fungicide,148-24-3,8-quinolinol,OC1=C2C(C=CC=N2)=CC=C1,rat,50,fc; food concentration,104 weeks,1500,73,3000,0
+1083,224,Oxydemeton-methyl,Hayes,1984,DAR,2005,organophosphorus,insecticide,301-12-2,"S-[2-(ethylsulfinyl)ethyl] O,O-dimethyl phosphorothioate",O=P(OC)(OC)SCCS(CC)=O,rat,50,fc; food concentration,120 weeks,1,0.02999999933,10,0.2199999988
+1084,425,Oxyfluorfen,Auelleta,1977,DAR,2007,diphenyl ether,herbicide,42874-03-3,2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene,FC(F)(F)C1=CC(Cl)=C(OC2=CC=C([N+]([O-])=O)C(OCC)=C2)C=C1,rat,50,fc; food concentration,104 weeks,40,1.799999952,1109,53
+1085,426,Paclobutrazol,Shaw,1986,DAR,2006,triazole,plant growth regulator,76738-62-0,"(R*,R*)-(+-)-beta-[(4-chlorophenyl)methyl]-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol",CC(C)(C(C(N2C=NC=N2)CC1=CC=C(C=C1)Cl)O)C,rat,60,fc; food concentration,104 weeks,50,2.200000048,250,11
+5044,986,Paraquat,Yoshida,1982,JMPR,2003,quaternary ammonium,herbicide,4685-14-7,"1,1′-dimethyl-4,4′-bipyridinium",C[N+](C=C2)=CC=C2C1=CC=[N+](C)C=C1,rat,80,fc; food concentration,104 weeks,30,0.7699999809,100,2.549999952
+5045,986,Paraquat,Toyoshima,1982,JMPR,2003,quaternary ammonium,herbicide,4685-14-7,"1,1′-dimethyl-4,4′-bipyridinium",C[N+](C=C2)=CC=C2C1=CC=[N+](C)C=C1,rat,62,fc; food concentration,104 weeks,100,3,300,8.869999886
+5046,986,Paraquat,Ishmael,1983,JMPR,2003,quaternary ammonium,herbicide,4685-14-7,"1,1′-dimethyl-4,4′-bipyridinium",C[N+](C=C2)=CC=C2C1=CC=[N+](C)C=C1,rat,70,fc; food concentration,113 weeks,25,1.25,75,3.75
+5454,429,Parathion,Daly,1984,JMPR,1995,organophosphorus,insecticide,56-38-2,"O,O-diethyl O-(4-nitrophenyl) phosphorothioate",CCOP(=S)(OCC)OC1=CC=C(C=C1)[N+](=O)[O-],rat,60,fc; food concentration,120 weeks,5,0.25,50,2.5
+5455,429,Parathion,Eiben,1987,JMPR,1995,organophosphorus,insecticide,56-38-2,"O,O-diethyl O-(4-nitrophenyl) phosphorothioate",CCOP(=S)(OCC)OC1=CC=C(C=C1)[N+](=O)[O-],rat,50,fc; food concentration,52 weeks,8,0.400000006,32,1.600000024
+1086,428,Parathion-methyl,Daly,1983,JMPR,1995,organophosphorus,insecticide,298-00-0,"O,O-dimethyl O-(4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC=C([N+]([O-])=O)C=C1,rat,60,fc; food concentration,104 weeks,5,0.25,50,2.5
+5443,428,Parathion-methyl,Daly,1991,JMPR,1995,organophosphorus,insecticide,298-00-0,"O,O-dimethyl O-(4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC=C([N+]([O-])=O)C=C1,rat,70,fc; food concentration,52 weeks,2.5,0.1099999994,12.5,0.5500000119
+5444,428,Parathion-methyl,Bomhard,1981,JMPR,1995,organophosphorus,insecticide,298-00-0,"O,O-dimethyl O-(4-nitrophenyl) phosphorothioate",S=P(OC)(OC)OC1=CC=C([N+]([O-])=O)C=C1,rat,50,fc; food concentration,104 weeks,2,0.1000000015,10,0.5
+3304,430,Penconazol,Basler,1985,DAR,2007,triazole,fungicide,66246-88-6,"1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole",CCCC(C2=CC=C(C=C2Cl)Cl)CN1C=NC=N1,rat,80,fc; food concentration,104 weeks,300,15.30000019,0,0
+1088,431,Pencycuron,Shirasu,1981,DAR,2006,"urea, phenyl",fungicide,66063-05-6,N-[(4-chlorophenyl)methyl]-N-cyclopentyl-N'-phenylurea,ClC1=CC=C(CN(C(NC3=CC=CC=C3)=O)C2CCCC2)C=C1,rat,80,fc; food concentration,104 weeks,500,18,5000,180
+6336,2059,Penflufen,Rascle,2009,EU,2011,anilide,fungicide,494793-67-8,"N-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide",CC(C)CC(C)C1=CC=CC=C1NC(C2=C(F)N(C)N=C2C)=O,rat,80,fc; food concentration,104 weeks,100,4,2000,0
+4484,1608,Penoxsulam,Johnson,2002,DAR,2010,sulfonamide,herbicide,219714-96-2,"2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide",O=S(NC1=NN2C(C(OC)=CN=C2OC)=N1)(C3=C(OCC(F)F)C=CC=C3C(F)(F)F)=O,rat,65,fd; food dose,104 weeks,0,5,0,50
+6488,1010,Penthiopyrad,Blumbach,2006,DAR,2011,pyrazole,fungicide,183675-82-3,"N-[2-(1,3-dimethylbutyl)-3-thienyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide",O=C(C2=CN(C)N=C2C(F)(F)F)NC1=C(C(C)CC(C)C)SC=C1,rat,50,fd; food dose,104 weeks,0,27,0,83
+6489,1010,Penthiopyrad,Blumbach,2006,DAR,2011,pyrazole,fungicide,183675-82-3,"N-[2-(1,3-dimethylbutyl)-3-thienyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide",O=C(C2=CN(C)N=C2C(F)(F)F)NC1=C(C(C)CC(C)C)SC=C1,rat,20,fd; food dose,52 weeks,0,25,0,100
+1089,67,Permethrin,Braun,1977,JMPR,1999,pyrethroid,insecticide,52645-53-1,"(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(C2C(/C=C(Cl)/Cl)C(C)2C)OCC1=CC(OC3=CC=CC=C3)=CC=C1,rat,60,fc; food concentration,104 weeks,100,5,500,25
+5217,67,Permethrin,Richards,1977,JMPR,1999,pyrethroid,insecticide,52645-53-1,"(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(C2C(/C=C(Cl)/Cl)C(C)2C)OCC1=CC(OC3=CC=CC=C3)=CC=C1,rat,60,fc; food concentration,104 weeks,500,25,1000,50
+6131,940,Pethoxamid,Waterson,2000,DAR,2002,amide,herbicide,106700-29-2,2-chloro-N-(2-ethoxyethyl)-N-(2-methyl-1-phenyl-1-propenyl)acetamide,C/C(C)=C(N(C(CCl)=O)CCOCC)/C1=CC=CC=C1,rat,80,fc; food concentration,104 weeks,25,1,400,17
+5722,2096,Phenothrin,Resnick,1981,JMPR,1988,pyrethroid,insecticide,26002-80-2,"(3-phenoxyphenyl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate",O=C(C(C(C)3C)C3/C=C(C)/C)OCC1=CC=CC(OC2=CC=CC=C2)=C1,rat,80,fc; food concentration,105 weeks,1000,50,3000,150
+1090,440,Phorat,,,JMPR,2004,organophosphorus,insecticide,298-02-2,"O,O-diethyl S-[(ethylthio)methyl] phosphorodithioate",CCSCSP(OCC)(OCC)=S,rat,50,fc; food concentration,104 weeks,1,0.05000000075,3,0.1599999964
+4290,442,Phosalon,Barker,1993,DAR,2005,organophosphorus,insecticide,2310-17-0,"S-[(6-chloro-2-oxo-3(2H)-benzoxazolyl)methyl] O,O-diethyl phosphorodithioate",CCOP(OCC)(SCN1C(OC2=C1C=CC(Cl)=C2)=O)=S,rat,50,fc; food concentration,104 weeks,50,1.799999952,500,23.39999962
+4303,443,Phosmet,Johnston,1966,DAR,2005,organophosphorus,insecticide,732-11-6,"S-[(1,3-dihydro1,3-dioxo-2H-isoindol-2-yl)methyl] O,O-dimethyl phosphorodithioate",S=P(OC)(OC)SCN1C(C(C=CC=C2)=C2C1=O)=O,rat,25,fc; food concentration,104 weeks,0,0,40,4
+4304,443,Phosmet,Chang,1988,DAR,2005,organophosphorus,insecticide,732-11-6,"S-[(1,3-dihydro1,3-dioxo-2H-isoindol-2-yl)methyl] O,O-dimethyl phosphorodithioate",S=P(OC)(OC)SCN1C(C(C=CC=C2)=C2C1=O)=O,rat,60,fc; food concentration,104 weeks,20,1.100000024,40,1.799999952
+5747,444,Phosphamidon,Mayhew,1986,JMPR,1986,organophosphorus,insecticide,13171-21-6,2-chloro-3-(diethylamino)-1-methyl-3-oxo-1-propenyl dimethyl phosphate,CCN(C(/C(Cl)=C(OP(OC)(OC)=O)/C)=O)CC,rat,60,fc; food concentration,104 weeks,1,0,30,0
+1093,1032,Picloram,Landry,1986,DAR,2007,pyridine,herbicide,1918-02-1,"4-amino-3,5,6-trichloro-2-pyridinecarboxylic acid",O=C(O)C1=NC(Cl)=C(Cl)C(N)=C1Cl,rat,60,fd; food dose,104 weeks,0,60,0,200
+4309,1032,Picloram,Cosse,1992,DAR,2007,pyridine,herbicide,1918-02-1,"4-amino-3,5,6-trichloro-2-pyridinecarboxylic acid",O=C(O)C1=NC(Cl)=C(Cl)C(N)=C1Cl,rat,50,fd; food dose,104 weeks,0,0,0,250
+6547,981,Picolinafen,Kelly,1999,DAR,2000,anilide,herbicide,137641-05-5,N-(4-fluorophenyl)-6-[3-(trifluoromethyl)phenoxy]-2-pyridinecarboxamide,FC(F)(F)C1=CC(OC2=CC=CC(C(NC3=CC=C(F)C=C3)=O)=N2)=CC=C1,rat,65,fc; food concentration,104 weeks,50,2.400000095,250,12.10000038
+6078,317,Picoxystrobin,Rattray,1999,JMPR,2012,strobilurin,fungicide,117428-22-5,methyl (αE)-α-(methoxymethylene)-2-[[[6-(trifluoromethyl)-2-pyridinyl]oxy]methyl]benzeneacetate,FC(F)(F)C1=CC=CC(OCC2=C(/C(C(OC)=O)=C\OC)C=CC=C2)=N1,rat,64,fc; food concentration,104 weeks,200,12,750,46
+7016,317,Picoxystrobin,Craig,2011,JMPR,2012,strobilurin,fungicide,117428-22-5,methyl (αE)-α-(methoxymethylene)-2-[[[6-(trifluoromethyl)-2-pyridinyl]oxy]methyl]benzeneacetate,FC(F)(F)C1=CC=CC(OCC2=C(/C(C(OC)=O)=C\OC)C=CC=C2)=N1,rat,80,fc; food concentration,104 weeks,1000,45,3500,162
+1094,933,Pinoxaden,Bachmann,2003,DAR,2006,others,herbicide,243973-20-8,"8-(2,6-diethyl-4-methylphenyl)-1,2,4,5-tetrahydro-7-oxo-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl 2,2-dimethylpropanoate",CCC1=C(C2=C(OC(C(C)(C)C)=O)N(CCOCC3)N3C2=O)C(CC)=CC(C)=C1,rat,90,gc; gavage concentration,104 weeks,0,10,0,100
+1095,447,Piperonylbutoxid,Graham,1987,JMPR,1995,others,insecticide,51-03-6,"5-((2-(2-butoxyethoxy)ethoxy)methyl)-6-propyl-1,3-benzodioxole",CCCCOCCOCCOCC1=C(CCC)C=C(OCO2)C2=C1,rat,60,fd; food dose,104 weeks,0,30,0,100
+4328,448,Pirimicarb,Tinston,1992,DAR,2004,carbamate,insecticide,23103-98-2,"2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl dimethylcarbamate",CN(C)C1=NC(C)=C(C)C(OC(N(C)C)=O)=N1,rat,64,fc; food concentration,104 weeks,75,3.700000048,250,12.30000019
+1097,450,Pirimiphos-methyl,Gore,1974,DAR,2005,organophosphorus,insecticide,29232-93-7,"O-[2-(diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl phosphorothioate",S=P(OC)(OC)OC1=NC(N(CC)CC)=NC(C)=C1,rat,40,fc; food concentration,104 weeks,10,0.400000006,50,2.099999905
+1098,2048,Prallethrin,,,UK,1995,pyrethroid,insecticide,23031-36-9,"2-methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate",O=C(C2C(/C=C(C)/C)C(C)2C)OC1CC(C(CC#C)=C1C)=O,rat,,fc; food concentration,104 weeks,0,3.269999981,0,16.5
+4348,453,Prochloraz,Colley,1982,DAR,2007,imidazole,fungicide,67747-09-5,"N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide",CCCN(C(N2C=CN=C2)=O)CCOC1=C(Cl)C=C(Cl)C=C1Cl,rat,60,fc; food concentration,104 weeks,150,5,625,21.5
+1100,455,Procymidon,Keller,1986,JMPR,2007,dicarboximide,fungicide,32809-16-8,"3-(3,5-dichlorophenyl)-1,5-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione",CC12CC(C(N(C3=CC(Cl)=CC(Cl)=C3)C2=O)=O)1C,rat,50,fc; food concentration,104 weeks,300,14,1000,48
+1101,456,Profenofos,Burdock,1981,JMPR,2007,organophosphorus,insecticide,41198-08-7,O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate,O=P(OCC)(SCCC)OC1=C(Cl)C=C(Br)C=C1,rat,60,fc; food concentration,104 weeks,100,5.699999809,0,0
+4361,313,Prohexadione,Inoue,1993,DAR,2009,others,plant growth regulator,127277-53-6,"calcium 3,5-dioxo-4-(1-oxopropyl)cyclohexanecarboxylate",O=C([O-])C(CC([O-])=C1C(CC)=O)CC1=O.[Ca+2],rat,80,fc; food concentration,104 weeks,2000,93.90000153,10000,469
+1102,460,Propamocarb,McFarlane,1998,DAR,2005,carbamate,fungicide,24579-73-5,propyl [3-(dimethylamino)propyl]carbamate,O=C(OCCC)NCCCN(C)C.[H]Cl,rat,70,fc; food concentration,104 weeks,2800,84,22400,682
+4377,460,Propamocarb,Hunter,1983,DAR,2005,carbamate,fungicide,24579-73-5,propyl [3-(dimethylamino)propyl]carbamate,O=C(OCCC)NCCCN(C)C.[H]Cl,rat,50,fc; food concentration,104 weeks,1000,25.60000038,0,0
+4378,460,Propamocarb,Blair,2001,DAR,2005,carbamate,fungicide,24579-73-5,propyl [3-(dimethylamino)propyl]carbamate,O=C(OCCC)NCCCN(C)C.[H]Cl,rat,70,fc; food concentration,104 weeks,0,0,2000,150
+4379,460,Propamocarb,Schoenmakers,2002,DAR,2005,carbamate,fungicide,24579-73-5,propyl [3-(dimethylamino)propyl]carbamate,O=C(OCCC)NCCCN(C)C.[H]Cl,rat,20,fc; food concentration,52 weeks,375,29,1500,114
+4127,1609,Propanil,Bellinger,1994,DAR,2008,anilide,herbicide,709-98-8,"N-(3,4-dichlorophenyl)propanamide",O=C(CC)NC1=CC(Cl)=C(Cl)C=C1,rat,70,fc; food concentration,104 weeks,0,0,200,9
+1103,461,Propaquizafop,Buser,1989,DAR,2006,2-(4aryloxyphenoxy)propionic acid,herbicide,111479-05-1,(R)-2-[[(1-methylethylidene)amino]oxy]ethyl 2-[4-[(6-chloro-2-quinoxalinyloxy]-phenoxy]propanoate,ClC1=CC=C2C(N=CC(OC3=CC=C(OC(C)C(OCCO/N=C(C)/C)=O)C=C3)=N2)=C1,rat,70,fd; food dose,104 weeks,0,1.5,0,5
+4118,461,Propaquizafop,Buser,1991,DAR,2006,2-(4aryloxyphenoxy)propionic acid,herbicide,111479-05-1,(R)-2-[[(1-methylethylidene)amino]oxy]ethyl 2-[4-[(6-chloro-2-quinoxalinyloxy]-phenoxy]propanoate,ClC1=CC=C2C(N=CC(OC3=CC=C(OC(C)C(OCCO/N=C(C)/C)=O)C=C3)=N2)=C1,rat,50,fd; food dose,104 weeks,0,5,0,25
+1104,462,Propargit,Ober,1966,DAR,2007,others,acaricide,2312-35-8,"2-[4(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl sulfite",CC(C)(C2=CC=C(C=C2)OC1CCCCC1OS(OCC#C)=O)C,rat,25,fd; food dose,104 weeks,0,5,0,15
+4108,462,Propargit,Trutter,1991,DAR,2007,others,acaricide,2312-35-8,"2-[4(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl sulfite",CC(C)(C2=CC=C(C=C2)OC1CCCCC1OS(OCC#C)=O)C,rat,60,fc; food concentration,104 weeks,80,3.460000038,400,24.20000076
+4109,462,Propargit,Goldenthal,1993,DAR,2007,others,acaricide,2312-35-8,"2-[4(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl sulfite",CC(C)(C2=CC=C(C=C2)OC1CCCCC1OS(OCC#C)=O)C,rat,60,fc; food concentration,104 weeks,0,0,0,0
+4110,462,Propargit,Goldenthal,1998,DAR,2007,others,acaricide,2312-35-8,"2-[4(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl sulfite",CC(C)(C2=CC=C(C=C2)OC1CCCCC1OS(OCC#C)=O)C,rat,55,fc; food concentration,87 weeks,80,3.730000019,400,25.20000076
+4759,2167,Propazin,,,USA,1998,triazine,herbicide,139-40-2,"6-chloro-N,N′-bis(1-methylethyl)-1,3,5-triazine-2,4-diamine",CC(C)NC1=NC(=NC(=N1)Cl)NC(C)C,rat,60,fc; food concentration,104 weeks,100,5.199999809,1000,51
+5585,3,Propham,Eiben,1988,JMPR,1992,"carbamate, phenyl",herbicide,122-42-9,1-methylethyl phenylcarbamate,O=C(OC(C)C)NC1=CC=CC=C1,rat,20,fc; food concentration,52 weeks,100,5.800000191,0,0
+5586,3,Propham,Eiben,1989,JMPR,1992,"carbamate, phenyl",herbicide,122-42-9,1-methylethyl phenylcarbamate,O=C(OC(C)C)NC1=CC=CC=C1,rat,20,fc; food concentration,104 weeks,100,5.699999809,500,29
+1105,454,Propiconazol,Hunter,1985,JMPR,2004,triazole,fungicide,60207-90-1,"1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole",CCCC1COC(C2=CC=C(Cl)C=C2Cl)(CN3N=CN=C3)O1,rat,70,fc; food concentration,104 weeks,500,18,2500,96
+1106,61,Propineb,Loser,1974,JMPR,1993,dithiocarbamate,fungicide,12071-83-9,"[[(1-methyl-1,2-ethanediyl)bis[carbamodithioato]](2-)]zinc homopolymer",[S]C(NC(C)CNC(S[Zn])=S)=S,rat,40,fc; food concentration,104 weeks,50,2.5,100,5
+5495,61,Propineb,Loser,1974,JMPR,1993,dithiocarbamate,fungicide,12071-83-9,"[[(1-methyl-1,2-ethanediyl)bis[carbamodithioato]](2-)]zinc homopolymer",[S]C(NC(C)CNC(S[Zn])=S)=S,rat,25,fc; food concentration,104 weeks,10,0.5,100,5
+4389,2032,Propisochlor,Korom,1995,DAR,2009,chloroacetanilide,herbicide,86763-47-5,2-chloro-N-(2-ethyl-6-methylphenyl)-N-[(1-methylethoxy)methyl]acetamide,O=C(N(C1=C(C)C=CC=C1CC)COC(C)C)CCl,rat,40,fd; food dose,52 weeks,0,63,0,200
+4390,2032,Propisochlor,Korom,1995,DAR,2009,chloroacetanilide,herbicide,86763-47-5,2-chloro-N-(2-ethyl-6-methylphenyl)-N-[(1-methylethoxy)methyl]acetamide,O=C(N(C1=C(C)C=CC=C1CC)COC(C)C)CCl,rat,60,fd; food dose,104 weeks,0,20,0,63
+5686,4,Propoxur,Jurek,1978,JMPR,1989,carbamate,insecticide,114-26-1,2-(1-methylethoxy)phenyl methylcarbamate,O=C(NC)OC(C=CC=C1)=C1OC(C)C,rat,20,fc; food concentration,78 weeks,200,0,800,0
+5687,4,Propoxur,,,JMPR,1989,carbamate,insecticide,114-26-1,2-(1-methylethoxy)phenyl methylcarbamate,O=C(NC)OC(C=CC=C1)=C1OC(C)C,rat,50,fc; food concentration,104 weeks,200,9.600000381,1000,48
+6508,315,Propoxycarbazon-Natrium,Wahle,1999,DAR,2001,"urea, triazinylsulfonyl",herbicide,181274-15-7,"sodium, methyl 2-[[[(4,5-dihydro-4-methyl-5-oxo-3-propoxy-1H-1,2,4-triazol-1-yl)carbonyl]amino]sulfonyl]benzoate",O=S(C1=C(C(OC)=O)C=CC=C1)([N-]C(N2N=C(OCCC)N(C)C2=O)=O)=O.[Na+],rat,50,fd; food dose,104 weeks,0,43,0,500
+5486,1610,Propylenethiourea,Weber,1979,JMPR,1993,,,,,C1CNC(=S)NC1,rat,40,fc; food concentration,104 weeks,10,0.5,100,5
+5489,1610,Propylenethiourea,Bomhard,1980,JMPR,1993,,,,,C1CNC(=S)NC1,rat,50,fc; food concentration,104 weeks,10,0.5600000024,100,5.599999905
+1107,5,Propyzamid,,,UK,1996,carboxamide,herbicide,23950-58-5,"3,5-dichloro-N-(1,1-dimethyl-2-propynyl)benzamide",O=C(NC(C)(C)C#C)C1=CC(Cl)=CC(Cl)=C1,rat,,fc; food concentration,104 weeks,0,8.460000038,0,42.5
+1108,939,Proquinazid,Malley,2002,DAR,2006,,fungicide,189278-12-4,6-iodo-2-propoxy-3-propyl-4(3H)-quinazolinone,IC1=CC=C(N=C(OCCC)N(CCC)C2=O)C2=C1,rat,80,fc; food concentration,104 weeks,30,1.200000048,300,12
+1109,6,Prosulfocarb,Pettersen,1988,DAR,2005,thiocarbamate,herbicide,52888-80-9,S-(phenylmethyl) dipropylcarbamothioate,O=C(SCC1=CC=CC=C1)N(CCC)CCC,rat,60,fc; food concentration,104 weeks,10,0.5,45,2.299999952
+6983,115,Prosulfuron,,,DAR,2013,"urea, triazinylsulfonyl",herbicide,94125-34-5,"N-[[3.(4.methoxy-6-methyl-1,3,5-triazin-2-yl)-amino]carbonyl]-2-(3,3,3-trifluoropropyl)benzene sulfonamide",O=S(C1=C(CCC(F)(F)F)C=CC=C1)(NC(NC2=NC(C)=NC(OC)=N2)=O)=O,rat,,fc; food concentration,104 weeks,0,8.600000381,0,88
+1110,329,Prothioconazol,Wirnitzer,2001,DAR,2004,triazole,fungicide,178928-70-6,"2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione",ClC1=C(CC(C3(CC3)Cl)(O)CN2N=CNC2=S)C=CC=C1,rat,50,gc; gavage concentration,104 weeks,0,5,0,50
+3977,329,Prothioconazol,Wirnitzer,2000,DAR,2004,triazole,fungicide,178928-70-6,"2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione",ClC1=C(CC(C3(CC3)Cl)(O)CN2N=CNC2=S)C=CC=C1,rat,20,gc; gavage concentration,52 weeks,0,50,0,750
+3995,2155,"Prothioconazol, desthio",Wirnitzer,2000,DAR,2004,,,,,C1CC1(C(CC2=CC=CC=C2Cl)(CN3C=NC=N3)O)Cl,rat,60,fc; food concentration,104 weeks,20,1.100000024,140,8
+1111,121,Pymetrozin,,1995,DAR,2013,"1,2,4-triazinone",insecticide,123312-89-0,"(E)-4,5-dihydro-6-methyl-4-[(3-pyridinylmethylene)amino]-1,2,4-triazin-3(2H)-one",O=C1N(/N=C/C2=CC=CN=C2)CC(C)=NN1,rat,80,fc; food concentration,104 weeks,100,3.75999999,1000,39.29999924
+6536,318,Pyraclostrobin,Mellert,1990,DAR,2003,strobilurin,fungicide,175013-18-0,"carbamic acid, [2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]methoxy-, methyl ester",CON(C(OC)=O)C(C=CC=C3)=C3COC2=NN(C=C2)C1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,75,3.400000095,200,9
+1113,1012,Pyrasulfotol,,,USA,2007,pyrazole,herbicide,365400-11-9,"(5-hydroxy-1,3-dimethyl-1H-pyrazol-4-yl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone",CS(C1=CC(C(F)(F)F)=CC=C1C(C2=C(O)N(C)N=C2C)=O)(=O)=O,rat,,fc; food concentration,104 weeks,25,1,250,10
+5573,8,Pyrazophos,Otaka,1983,JMPR,1992,organophosphorus,fungicide,13457-18-6,"ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate",O=C(C(C(C)=N2)=CN1C2=CC(OP(OCC)(OCC)=S)=N1)OCC,rat,40,fc; food concentration,52 weeks,20,1,200,11
+5578,8,Pyrazophos,Til,1979,JMPR,1992,organophosphorus,fungicide,13457-18-6,"ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate",O=C(C(C(C)=N2)=CN1C2=CC(OP(OCC)(OCC)=S)=N1)OCC,rat,30,fc; food concentration,104 weeks,50,2.5,0,0
+5579,8,Pyrazophos,Tennekes,1991,JMPR,1992,organophosphorus,fungicide,13457-18-6,"ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate",O=C(C(C(C)=N2)=CN1C2=CC(OP(OCC)(OCC)=S)=N1)OCC,rat,50,fc; food concentration,117 weeks,2,0.1000000015,80,4
+3955,10,Pyrethrine,Goldenthal,1990,DAR,2007,pyrethrin,insecticide,8003-34-7,Pyrethrins,CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C,rat,60,fc; food concentration,104 weeks,100,4.400000095,1000,43
+1114,106,Pyridaben,Holmes,1990,DAR,2007,pyridazinone,insecticide,96489-71-3,"4-chloro-2-(1,1-dimethylethyl)-5-[[[4-(1,1-dimethylethyl)phenyl]methyl]thio]-3(2H)-pyridazinone",CC(C)(C)C1=CC=C(CSC2=C(Cl)C(N(C(C)(C)C)N=C2)=O)C=C1,rat,85,fc; food concentration,104 weeks,28,1.129999995,80,5
+1115,2043,Pyridalyl,,,USA,2008,others,insecticide,179101-81-6,"2-[3-[2,6-dichloro-4-[(3,3-dichloro-2-propenyl)oxy]phenoxy]propoxy]-5-(trifluoromethyl)pyridine",FC(F)(F)C1=CC=C(OCCCOC2=C(Cl)C=C(OC/C=C(Cl)\Cl)C=C2Cl)N=C1,rat,,fc; food concentration,104 weeks,0,3.400000095,0,17.10000038
+6969,11,Pyridate,Anonymous,,DAR,2013,others,herbicide,55512-33-9,O-(6-chloro-3-phenyl-4-pyridazinyl) S-octyl carbonothioate,CCCCCCCCSC(OC1=C(C2=CC=CC=C2)N=NC(Cl)=C1)=O,rat,75,fd; food dose,104 weeks,0,18,0,115
+3862,143,Pyrimethanil,Rees,1993,DAR,2004,"pyrimidine, anilino",fungicide,53112-28-0,"4,6-dimethyl-N-phenyl-2-pyrimidinamine",CC1=NC(NC2=CC=CC=C2)=NC(C)=C1,rat,70,fc; food concentration,104 weeks,400,17,5000,221
+6455,2152,Pyriofenon,Anonymous,2010,DAR,2012,,fungicide,688046-61-9,"(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)methanone",CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC,rat,20,fc; food concentration,52 weeks,200,8.510000229,1000,42.90000153
+6456,2152,Pyriofenon,Anonymous,2010,DAR,2012,,fungicide,688046-61-9,"(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)methanone",CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC,rat,50,fc; food concentration,104 weeks,200,7.25,1000,36.40000153
+1117,107,Pyriproxyfen,Osheroff,1991,DAR,2005,diphenyl ether,insecticide,95737-68-1,2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine,CC(COC2=CC=C(OC3=CC=CC=C3)C=C2)OC1=CC=CC=N1,rat,80,fc; food concentration,104 weeks,600,27.20000076,3000,138.6999969
+6586,993,Pyroxsulam,Stebbins,2008,DAR,2012,sulfonamide,herbicide,422556-08-9,"N-(5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)-3-pyridinesulfonamide",O=S(NC1=NN2C(N=C(OC)C=C2OC)=N1)(C3=C(OC)N=CC=C3C(F)(F)F)=O,rat,65,fd; food dose,104 weeks,0,100,0,1000
+1119,1045,Quinmerac,Schilling,1990,DAR,2007,"quinoline, carboxylic acid",herbicide,90717-03-6,7-chloro-3-methyl-8-quinolinecarboxylic acid,ClC1=CC=C(C=C(C)C=N2)C2=C1C(O)=O,rat,50,fc; food concentration,104 weeks,6000,317,0,0
+3454,1045,Quinmerac,Schilling,1990,DAR,2007,"quinoline, carboxylic acid",herbicide,90717-03-6,7-chloro-3-methyl-8-quinolinecarboxylic acid,ClC1=CC=C(C=C(C)C=N2)C2=C1C(O)=O,rat,25,fc; food concentration,52 weeks,6000,364,12000,740
+1120,973,Quinoclamine,Husband,1991,DAR,2006,quinone,algicide,2797-51-5,"2-amino-3-chloro-1,4-naphthalenedione",O=C2C(N)=C(Cl)C(C1=CC=CC=C12)=O,rat,50,fc; food concentration,104 weeks,4,0.2099999934,52,2.890000105
+1121,334,Quinoxyfen,Redmond,1995,JMPR,2006,"quinoline, phenoxy",fungicide,124495-18-7,"5,7-dichloro-4-(4-fluorophenoxy)quinoline",FC(C=C3)=CC=C3OC1=CC=NC2=C1C(Cl)=CC(Cl)=C2,rat,50,fd; food dose,104 weeks,0,20,0,80
+1122,14,Quintozen,Goldenthal,1991,JMPR,1995,"benzene, nitro",fungicide,82-68-8,pentachloronitrobenzene,[O-][N+](C(C(Cl)=C(Cl)C(Cl)=C1Cl)=C1Cl)=O,rat,50,fc; food concentration,104 weeks,20,0.8999999762,3000,141
+1123,15,Quizalofop-ethyl,Barnard,1985,DAR,2007,"propionic acid, aryloxyphenoxy",herbicide,76578-14-8,"2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propionsäure, ethylester",CCOC(C(OC3=CC=C(C=C3)OC2=NC1=CC=C(Cl)C=C1N=C2)C)=O,rat,50,fc; food concentration,104 weeks,25,0.8999999762,100,15.5
+3433,2153,Quizalofop-P-tefuryl,Goldenthal,1994,DAR,2007,"(4-aryloxyphenoxy)propionic acid, 2-",herbicide,119738-06-6,(tetrahydro-2-furanyl)methyl (2R)-2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propanoate,CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl,rat,65,fc; food concentration,104 weeks,25,1.299999952,750,39.5
+1124,114,Rimsulfuron,Keller,1991,DAR,2003,"urea, sulfonyl",herbicide,122931-48-0,"N-[[4,6-dimethoxy-2-pyrimidyl)amino]carbonyl]-3-(etylsulfonyl)-2-pyridinesulfonamide",O=S(C1=C(S(CC)(=O)=O)C=CC=N1)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O,rat,62,fc; food concentration,104 weeks,300,11.80000019,3000,121
+4742,2023,Saflufenacil,Kaspers,2007,JMPR,2011,uracil,herbicide,372137-35-4,"2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]benzamide",O=C(NS(N(C(C)C)C)(=O)=O)C1=CC(N2C(C=C(C(F)(F)F)N(C)C2=O)=O)=C(F)C=C1Cl,rat,50,fc; food concentration,104 weeks,100,6.199999809,500,31.39999962
+6259,2017,Sedaxan,Perry,2010,DAR,2011,pyrazole,fungicide,874967-67-6,"N-[2-[1,1′-bicyclopropyl]-2-ylphenyl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide",O=C(C2=CN(C)N=C2C(F)F)NC1=C(C3CC3C4CC4)C=CC=C1,rat,64,fc; food concentration,104 weeks,200,11,1200,67
+3396,2091,Sintofen,Richard,1996,DAR,2007,others,plant growth regulator,130561-48-7,"1-(4-chlorophenyl)-1,4-dihydro-5-(2-methoxyethoxy)-4-oxo-3-cinnolinecarboxylic acid",COCCOC1=CC=CC2=C1C(=O)C(=NN2C3=CC=C(C=C3)Cl)C(=O)O,rat,80,fc; food concentration,104 weeks,300,12.60000038,1700,0
+6644,1029,Spinetoram,Yano,2007,DAR,2012,spinosyn,insecticide,187166-40-1,"(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-α-L-mannopyranosyl)oxy]-13-[[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2,3,3a,4,5,5a,5b,6,9,10,11,12,13,14,16a,16b-hexadecahydro-14-methyl-1H-as-i",C[C@H]([C@@H](N(C)C)CC5)O[C@H]5O[C@@H]2[C@@H](C)C(C1=C[C@]3([H])[C@](CC[C@@]4([H])[C@]([H])3C[C@H](O[C@@H]6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C4)([H])[C@@]([H])1CC(O[C@@H](CC)CCC2)=O)=O,rat,65,fc; food concentration,104 weeks,250,10.80000019,500,21.60000038
+1125,357,Spinosad,Bond,1995,JMPR,2001,others,insecticide,168316-95-8,"(2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-2-[(6-deoxy-2,3,4-tri-O-methyl-α-L-mannopyranosyl)oxy]-13-[[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-14-methyl-1H-as-indaceno[3,",CCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C(=CC3C2CC(=O)O1)C)OC5C(C(C(C(O5)C)OC)OC)OC)C)OC6CCC(C(O6)C)N(C)C,rat,65,fc; food concentration,104 weeks,50,2.400000095,200,9.5
+1126,320,Spirodiclofen,Wimitzer,2000,DAR,2004,tetronic acid,acaricide,148477-71-8,"Butonic acid, 2,2-dimethyl-,3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5] dec-3-en-4-yl ester",O=C1OC3(CCCCC3)C(OC(C(C)(C)CC)=O)=C1C2=C(Cl)C=C(Cl)C=C2,rat,50,fc; food concentration,108 weeks,100,4.110000134,350,14.72000027
+3356,1021,Spiromesifen,Schladt,2001,DAR,2004,tetronic acid,insecticide,283594-90-1,"2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate",CC1=CC(C)=CC(C)=C1C2=C(OC(CC(C)(C)C)=O)C3(CCCC3)OC2=O,rat,25,fc; food concentration,52 weeks,125,6.5,300,15.89999962
+3357,1021,Spiromesifen,Schladt,2001,DAR,2004,tetronic acid,insecticide,283594-90-1,"2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate",CC1=CC(C)=CC(C)=C1C2=C(OC(CC(C)(C)C)=O)C3(CCCC3)OC2=O,rat,50,fc; food concentration,104 weeks,125,6.099999905,300,14.80000019
+3308,994,Spirotetramat,Wahle,2005,DAR,2008,tetramic acid,insecticide,203313-25-1,"cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate",CC1=CC=C(C)C=C1C(C(N3)=O)=C(OC(OCC)=O)C23CCC(OC)CC2,rat,25,fc; food concentration,52 weeks,250,13.19999981,3500,189
+3309,994,Spirotetramat,Wahle,2006,DAR,2008,tetramic acid,insecticide,203313-25-1,"cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate",CC1=CC=C(C)C=C1C(C(N3)=O)=C(OC(OCC)=O)C23CCC(OC)CC2,rat,55,fc; food concentration,104 weeks,250,13.19999981,3500,189
+3271,345,Spiroxamine,Eiben,1994,DAR,2009,others,fungicide,118134-30-8,"8-(1,1-dimethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro[4.5]decane -2-methanamine",CC(C)(C)C1CCC2(OC(CN(CCC)CC)CO2)CC1,rat,50,fc; food concentration,104 weeks,70,4.21999979,490,32.81000137
+1130,161,Sulcotrione,Pavkov,1990,DAR,2006,triketone,herbicide,99105-77-8,"2-[2-chloro-4-(metylsulfonyl)benzoyl]-1,3-cyclohexandione",CS(C(C=C2Cl)=CC=C2C(C(C(CCC1)=O)C1=O)=O)(=O)=O,rat,60,fc; food concentration,104 weeks,50,2,1900,72
+3255,161,Sulcotrione,Potrepka,1991,DAR,2006,triketone,herbicide,99105-77-8,"2-[2-chloro-4-(metylsulfonyl)benzoyl]-1,3-cyclohexandione",CS(C(C=C2Cl)=CC=C2C(C(C(CCC1)=O)C1=O)=O)(=O)=O,rat,50,fc; food concentration,104 weeks,1,0.03999999911,10,0.400000006
+1131,2044,Sulfentrazon,,,USA,1997,anilide,herbicide,122836-35-5,"N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide",CS(NC1=C(Cl)C=C(Cl)C(N2C(N(C(F)F)C(C)=N2)=O)=C1)(=O)=O,rat,60,fc; food concentration,104 weeks,600,36.40000153,1000,67
+6955,170,Sulfosulfuron,Naylor,1997,DAR,2013,"urea, sulfonyl",herbicide,141776-32-1,"N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide",O=S(C1=C(S(CC)(=O)=O)N=C2N1C=CC=C2)(NC(NC3=NC(OC)=CC(OC)=N3)=O)=O,rat,,fc; food concentration,104 weeks,500,24.39999962,5000,1296.5
+6408,2018,Sulfoxaflor,Stebbins,2010,DAR,2012,others,insecticide,946578-00-3,N-[methyloxido[1-[6-(trifluoromethyl)-3-pyridinyl]ethyl]-λ4-sulfanylidene]cyanamide,FC(F)(F)C1=CC=C(C(S(C)(=O)=NC#N)C)C=N1,rat,60,fc; food concentration,104 weeks,25,1.039999962,100,4.239999771
+3245,336,tau-Fluvalinat,Goldenthal,1984,DAR,2009,pyrethroid,insecticide,102851-06-9,cyano(3-phenoxyphenyl)methyl N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valinate,FC(F)(F)C1=CC=C(N[C@@H]([C@H](C)C)C(OC(C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O)C(Cl)=C1,rat,85,gd; gavage dose,104 weeks,0,0.5,0,1
+3228,23,Tebuconazol,Bomhard,1988,DAR,2006,triazole,fungicide,107534-96-3,"(+-)-alpha-[2-(4-chlorophenyl)ethyl]-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol",CC(C)(C(CCC1=CC=C(Cl)C=C1)(CN2C=NC=N2)O)C,rat,60,fc; food concentration,104 weeks,300,15.89999962,1000,55
+3216,117,Tebufenozid,Trutter,1992,DAR,2005,carboxamide,insecticide,112410-23-8,"3,5-diemthylbenzoic acid 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide",O=C(NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O)C1=CC=C(C=C1)CC,rat,70,fc; food concentration,104 weeks,100,4.800000191,1000,48.40000153
+1135,69,Tebufenpyrad,Mitchell,1992,DAR,2007,carboxamide,acaricide,119168-77-3,"4-chloro-N[[4-(1,1-dimethylethyl)phenyl]methyl]-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide",CN1N=C(C(Cl)=C1C(NCC2=CC=C(C=C2)C(C)(C)C)=O)CC,rat,65,fc; food concentration,104 weeks,20,0.8000000119,150,6.5
+5469,25,Tecnazen,Ben-Dyke,1978,JMPR,1994,"benzene, nitro",fungicide,117-18-0,"1,2,4,5-tetrachloro-3-nitrobenzene",ClC1=C(Cl)C=C(Cl)C(Cl)=C1[N+]([O-])=O,rat,65,fc; food concentration,104 weeks,1500,56,0,0
+3111,26,Teflubenzuron,Suter,1987,DAR,2007,"urea, benzoyl",insecticide,83121-18-0,"N-[[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl]-2,6-difluorobenzamide",FC1=CC=CC(F)=C1C(NC(NC2=CC(Cl)=C(C(Cl)=C2F)F)=O)=O,rat,70,fc; food concentration,120 weeks,100,4.800000191,500,24.79999924
+3112,26,Teflubenzuron,Tennekes,1989,DAR,2007,"urea, benzoyl",insecticide,83121-18-0,"N-[[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl]-2,6-difluorobenzamide",FC1=CC=CC(F)=C1C(NC(NC2=CC(Cl)=C(C(Cl)=C2F)F)=O)=O,rat,60,fc; food concentration,104 weeks,0,0,2500,122.5
+1138,1027,Tefluthrin,Stonard,1986,DAR,2006,pyrethroid,insecticide,79538-32-2,"(2,3,5,6-tetrafluoro-4-methylphenyl)methyl (1R,3R)-rel-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]-2,2-dimethylcyclopropanecarboxylate",FC(F)(F)/C(Cl)=C/C1C(C)(C)C1C(OCC2=C(F)C(F)=C(C)C(F)=C2F)=O,rat,76,fc; food concentration,104 weeks,25,1.5,100,5.900000095
+1139,950,Tembotrion,Kennel,2005,DAR,2008,triketone,herbicide,335104-84-2,"2-[2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoyl]-1,3-cyclohexanedione",O=C(CCC1)C(C(C2=CC=C(S(=O)(C)=O)C(COCC(F)(F)F)=C2Cl)=O)C1=O,rat,75,fc; food concentration,104 weeks,2,0.03999999911,20,1.049999952
+4877,2169,Temephos,Tegeris,1977,JMPR,2006,organophosphorus,insect attractant,3383-96-8,"O,O′-(thiodi-4,1-phenylene) bis(O,O-dimethyl phosphorothioate)",COP(=S)(OC)OC1=CC=C(C=C1)SC2=CC=C(C=C2)OP(=S)(OC)OC,rat,60,fc; food concentration,104 weeks,300,15,0,0
+5067,28,Terbufos,Daly,1987,JMPR,2003,organophosphorus,insecticide,13071-79-9,"S-[[(1,1-dimethylethyl)thio]methyl] O,O-diethyl phosphorodithioate",S=P(OCC)(OCC)SCSC(C)(C)C,rat,30,fc; food concentration,52 weeks,1,0.0549999997,0,0
+5071,28,Terbufos,Rapp,1974,JMPR,2003,organophosphorus,insecticide,13071-79-9,"S-[[(1,1-dimethylethyl)thio]methyl] O,O-diethyl phosphorodithioate",S=P(OCC)(OCC)SCSC(C)(C)C,rat,60,fc; food concentration,104 weeks,1,0.05000000075,2,0.1000000015
+3044,30,Terbuthylazin,Gfeller,1983,DAR,2007,triazine,herbicide,5915-41-3,"6-chloro-N-(1,1-dimethylethyl)-N'-ethyl-1,3,5-triazine-2,4-diamine",ClC1=NC(NCC)=NC(NC(C)(C)C)=N1,rat,80,fc; food concentration,104 weeks,0,0,30,1.24000001
+3045,30,Terbuthylazin,Gfeller,1983,DAR,2007,triazine,herbicide,5915-41-3,"6-chloro-N-(1,1-dimethylethyl)-N'-ethyl-1,3,5-triazine-2,4-diamine",ClC1=NC(NCC)=NC(NC(C)(C)C)=N1,rat,80,fc; food concentration,104 weeks,6,0.349999994,30,1.590000033
+3046,30,Terbuthylazin,Ramesh,2001,DAR,2007,triazine,herbicide,5915-41-3,"6-chloro-N-(1,1-dimethylethyl)-N'-ethyl-1,3,5-triazine-2,4-diamine",ClC1=NC(NCC)=NC(NC(C)(C)C)=N1,rat,50,fc; food concentration,104 weeks,10,0.400000006,40,1.700000048
+1140,109,Tetraconazol,Crome,1992,DAR,2005,triazole,fungicide,112281-77-3,"(+-)-1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1H-1,2,4-triazole",FC(C(F)(OCC(C2=CC=C(C=C2Cl)Cl)CN1C=NC=N1)F)F,rat,50,fc; food concentration,104 weeks,10,0.5,80,3.400000095
+4897,37,Thiabendazol,Woodard,1964,JMPR,1970,benzimidazole,fungicide,148-79-8,2-(4-thiazolyl)-1H-benzimidazole,C2(C3=CSC=N3)=NC1=CC=CC=C1N2,rat,35,fd; food dose,104 weeks,0,10,0,40
+1142,358,Thiacloprid,Bomhard,1998,JMPR,2006,pyridine,insecticide,111988-49-9,3-(2-chloro-5-pyridylmethyl)-2-cyaniminothiazolidine,N#C/N=C1SCCN/1CC2=CC=C(Cl)N=C2,rat,50,fc; food concentration,108 weeks,25,1.200000048,50,2.5
+5913,308,Thiamethoxam,Bachmann,1998,JMPR,2010,guanidine,insecticide,153719-23-4,"3-[(2-chloro-5-thiazolyl)methyl]tetrahydro-5-methyl-N-nitro-4H-1,3,5-oxadiazin-4-imine",ClC1=NC=C(CN2/C(N(C)COC2)=N/[N+]([O-])=O)S1,rat,70,fc; food concentration,104 weeks,1000,50.29999924,3000,155
+1143,2045,Thiazopyr,,,USA,1997,pyridine,herbicide,117718-60-2,"methyl 2-(difluoromethyl)-5-(4,5-dihydro-2-thiazolyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate",FC(F)C1=NC(C(F)(F)F)=C(C2=NCCS2)C(CC(C)C)=C1C(OC)=O,rat,,fc; food concentration,104 weeks,0,4.400000095,0,44.20000076
+6704,1016,Thiencarbazon-methyl,Schladt,2007,DAR,2012,triazole,herbicide,317815-83-1,"methyl 4-[[[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carbonyl]amino]sulfonyl]-5-methyl-3-thiophenecarboxylic acid",O=S(NC(N1N=C(OC)N(C)C1=O)=O)(C2=C(C)SC=C2C(OC)=O)=O,rat,70,fc; food concentration,104 weeks,2500,115,5000,234
+1144,1040,Thiobencarb,Cummins,1984,DAR,2005,thiocarbamate,herbicide,28249-77-6,S-[(4-chlorophenyl)methyl] diethylcarbamothioate,O=C(N(CC)CC)SCC1=CC=C(Cl)C=C1,rat,100,fc; food concentration,104 weeks,20,0.8999999762,100,4.300000191
+1145,40,Thiodicarb,Atkinson,1994,DAR,2005,"carbamate, oxime",insecticide,59669-26-0,"dimethyl N,N′-[thiobis[(methylimino)carbonyloxy]]bis[ethanimidothioate]",CS/C(C)=N/OC(N(SN(C(O/N=C(SC)\C)=O)C)C)=O,rat,15,fc; food concentration,52 weeks,0,0,60,5
+2988,40,Thiodicarb,DePass,1981,DAR,2005,"carbamate, oxime",insecticide,59669-26-0,"dimethyl N,N′-[thiobis[(methylimino)carbonyloxy]]bis[ethanimidothioate]",CS/C(C)=N/OC(N(SN(C(O/N=C(SC)\C)=O)C)C)=O,rat,120,fd; food dose,104 weeks,0,3,0,10
+2989,40,Thiodicarb,Atkinson,1994,DAR,2005,"carbamate, oxime",insecticide,59669-26-0,"dimethyl N,N′-[thiobis[(methylimino)carbonyloxy]]bis[ethanimidothioate]",CS/C(C)=N/OC(N(SN(C(O/N=C(SC)\C)=O)C)C)=O,rat,50,fc; food concentration,104 weeks,60,3,200,12
+1146,42,Thiophanat-methyl,Hashimoto,1972,JMPR,1995,"urea, thio",fungicide,23564-05-8,"dimethyl [1,2-phenylenebis(iminocarbonothioyl]bis[carbamate]",S=C(NC(OC)=O)NC(C=CC=C1)=C1NC(NC(OC)=O)=S,rat,35,fc; food concentration,104 weeks,160,8,640,32
+5422,42,Thiophanat-methyl,Takaori,1993,JMPR,1995,"urea, thio",fungicide,23564-05-8,"dimethyl [1,2-phenylenebis(iminocarbonothioyl]bis[carbamate]",S=C(NC(OC)=O)NC(C=CC=C1)=C1NC(NC(OC)=O)=S,rat,60,fc; food concentration,104 weeks,200,8.800000191,1200,53
+1147,43,Thiram,Miata,1991,JMPR,1992,dithiocarbamate,fungicide,137-26-8,tetramethylthioperoxydicarbonic diamide,S=C(SSC(N(C)C)=S)N(C)C,rat,64,fc; food concentration,104 weeks,30,1.200000048,300,12
+5565,43,Thiram,Kehoe,1991,JMPR,1992,dithiocarbamate,fungicide,137-26-8,tetramethylthioperoxydicarbonic diamide,S=C(SSC(N(C)C)=S)N(C)C,rat,60,fc; food concentration,104 weeks,30,1.5,150,7.300000191
+1148,111,Tolclofos-methyl,Pence,1982,DAR,2003,organophosphorus,fungicide,57018-04-9,"O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl phosphorothioate",COP(OC1=C(Cl)C=C(C)C=C1Cl)(OC)=S,rat,65,fc; food concentration,104 weeks,1000,42,0,0
+6859,2767,Tolfenpyrad,Chida,1999,JMPR,2013,pyrazole,insecticide,129558-76-5,4-chloro-3-ethyl-1-methyl-N-[[4-(4-methylphenoxy)phenyl]methyl]-1H-pyrazole-5-carboxamide,CCC1=NN(C(=C1Cl)C(=O)NCC2=CC=C(C=C2)OC3=CC=C(C=C3)C)C,rat,60,fc; food concentration,104 weeks,15,0.5609999895,40,1.5
+1149,44,Tolylfluanid,Krötlinger,1982,DAR,2005,others,fungicide,731-27-1,"1,1-dichloro-N-[(dimethylamino)sulfonyl)]-1-fluroro-N-(4-methylphenyl)methanesulfenamide",CN(C)S(N(SC(F)(Cl)Cl)C1=CC=C(C)C=C1)(=O)=O,rat,50,fc; food concentration,104 weeks,300,20,1500,100
+2936,44,Tolylfluanid,Leser,1996,DAR,2005,others,fungicide,731-27-1,"1,1-dichloro-N-[(dimethylamino)sulfonyl)]-1-fluroro-N-(4-methylphenyl)methanesulfenamide",CN(C)S(N(SC(F)(Cl)Cl)C1=CC=C(C)C=C1)(=O)=O,rat,50,fc; food concentration,104 weeks,300,18,1500,90
+1150,936,Topramezon,Kspers,2002,DAR,2006,pyrazole,herbicide,210631-68-8,"[3-(4,5-dihydro-3-isoxazolyl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)methanone",CC1=C(C2=NOCC2)C(S(C)(=O)=O)=CC=C1C(C3=C(O)N(C)N=C3)=O,rat,50,fc; food concentration,104 weeks,6,0.400000006,60,3.599999905
+1151,46,Tralkoxydim,Stonard,1994,DAR,2006,cyclohexanedione oxime,herbicide,87820-88-0,"2-[1-(ethoxyimino)propyl]-3-hydroxy-5-(2,4,6-trimethylphenyl)-2-cyclohexen-1-one",O=C1C(/C(CC)=N/OCC)=C(O)CC(C2=C(C)C=C(C)C=C2C)C1,rat,64,fc; food concentration,104 weeks,50,2.299999952,500,23
+1152,2049,Transfluthrin,,,UK,1997,pyrethrin,insecticide,118712-89-3,"(2,3,5,6-tetrafluorophenyl)methyl (1R,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate",O=C(C2C(/C=C(Cl)/Cl)C(C)2C)OCC1=C(F)C(F)=CC(F)=C1F,rat,,fc; food concentration,104 weeks,0,1,0,10
+1153,47,Triadimefon,Bomhard,1991,JMPR,2004,triazole,fungicide,43121-43-3,"1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triizol-1yl)-2-butanone",O=C(C(C)(C)C)C(N2C=NC=N2)OC1=CC=C(Cl)C=C1,rat,60,fc; food concentration,104 weeks,300,16.39999962,1800,114
+5001,47,Triadimefon,Bomhard,1978,JMPR,2004,triazole,fungicide,43121-43-3,"1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triizol-1yl)-2-butanone",O=C(C(C)(C)C)C(N2C=NC=N2)OC1=CC=C(Cl)C=C1,rat,50,fc; food concentration,104 weeks,50,2.380000114,500,24.29999924
+1154,62,Triadimenol,Kroetlinger,1994,DAR,2006,triazole,fungicide,55219-65-3,"beta-(4-chlorophenoxy)-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol",ClC1=CC=C(OC(N2N=CN=C2)C(O)C(C)(C)C)C=C1,rat,60,fc; food concentration,104 weeks,125,5,500,19
+1155,2009,Tri-allat,Stout,1989,DAR,2007,thiocarbamate,herbicide,2303-17-5,"S-(2,3,3-trichloro-2-propenyl) bis(1-methylethyl)carbamothioate",O=C(SC/C(Cl)=C(Cl)\Cl)N(C(C)C)C(C)C,rat,60,fc; food concentration,104 weeks,50,2.5,250,13
+2864,2009,Tri-allat,Marias,1976,DAR,2007,thiocarbamate,herbicide,2303-17-5,"S-(2,3,3-trichloro-2-propenyl) bis(1-methylethyl)carbamothioate",O=C(SC/C(Cl)=C(Cl)\Cl)N(C(C)C)C(C)C,rat,50,fc; food concentration,104 weeks,100,4.300000191,200,8.600000381
+1156,48,Triasulfuron,,,UK,1992,"urea, triazinylsulfonyl",herbicide,82097-50-5,"2-(2-chloroethoxy)-N-[[4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]benzenesulfonamide",ClCCOC1=CC=CC=C1S(NC(NC2=NC(OC)=NC(C)=N2)=O)(=O)=O,rat,,fc; food concentration,104 weeks,0,0.3000000119,0,30
+1157,146,Triazamate,Wolfe,1992,UK,1998,triazole,insecticide,112143-82-5,"ethyl[[1-[(dimethylamino)carbonyl]-3-(1,1-dimethylethyl)1H-1,2,4triazol-=5-yl]thio]acetate",O=C(OCC)CSC1=NC(C(C)(C)C)=NN1C(N(C)C)=O,rat,70,fc; food concentration,104 weeks,10,0.4499999881,250,12
+1158,49,Triazophos,Tennekes,1990,JMPR,2002,organophosphorus,insecticide,24017-47-8,"O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) phosphorothioate",CCOP(OC2=NN(C=N2)C1=CC=CC=C1)(OCC)=S,rat,80,fc; food concentration,104 weeks,3,0.150000006,27,1.299999952
+1159,943,Triazoxid,Eiben,1988,DAR,2007,imidazole,fungicide,72459-58-6,"7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide",[O-][N+]2=NC(N3C=CN=C3)=NC1=CC=C(Cl)C=C12,rat,60,fc; food concentration,104 weeks,0,0,0,0.05000000075
+1160,1997,Tribenuron,Tobia,1987,DAR,2003,,,106040-48-6,,O=C(O)C1=CC=CC=C1S(=O)(NC(N(C2=NC(OC)=NC(C)=N2)C)=O)=O,rat,72,fc; food concentration,104 weeks,250,10,1250,55
+2834,51,Trichlorfon,Hayes,1989,DAR,2004,organophosphorus,insecticide,52-68-6,"dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate",OC(C(Cl)(Cl)Cl)P(OC)(OC)=O,rat,50,fc; food concentration,104 weeks,100,4.5,300,13.30000019
+2836,51,Trichlorfon,Christenson,1989,DAR,2004,organophosphorus,insecticide,52-68-6,"dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate",OC(C(Cl)(Cl)Cl)P(OC)(OC)=O,rat,50,fc; food concentration,104 weeks,0,0,0,0
+1161,975,Triclopyr,Philips,1984,DAR,2003,pyridine,herbicide,55335-06-3,"[(3,5,6-trichloro-2-pyridinyl)oxy]acetic acid",O=C(O)COC1=NC(Cl)=C(Cl)C=C1Cl,rat,50,fd; food dose,104 weeks,0,30,0,0
+2776,975,Triclopyr,Eisenbrandt,1987,DAR,2003,pyridine,herbicide,55335-06-3,"[(3,5,6-trichloro-2-pyridinyl)oxy]acetic acid",O=C(O)COC1=NC(Cl)=C(Cl)C=C1Cl,rat,50,fd; food dose,104 weeks,0,3,0,1
+1162,1034,Tricyclazol,Howard,1977,DAR,2007,triazole,fungicide,41814-78-2,"5-methyl-1,2,4-triazolo[3,4-b]benzothiazole",CC1=C(N2C(S3)=NN=C2)C3=CC=C1,rat,40,fc; food concentration,104 weeks,275,11,620,26
+5017,352,Trifloxystrobin,Gerspach,1997,JMPR,2004,strobilurin,fungicide,141517-21-7,"(E,E)-alpha-(methoxyimino)-2-[[[[1-[3(trifluoromethyl)phenyl]-ethylidene]amino]oxy]methyl]-benzeneacetic acid methyl ester",CO\N=C(C(OC)=O)/C1=C(CO/N=C(C)/C2=CC=CC(C(F)(F)F)=C2)C=CC=C1,rat,50,fc; food concentration,104 weeks,250,9.800000191,750,29.70000076
+1164,53,Triflumizole,Virgo,1984,DAR,2006,imidazole,fungicide,68694-11-1,(E)-1-[1-[[4-chloro-2-(trifluoromethyl)phenyl]imino]-2-propoxyethyl]-1H-imidazole (CA),CCCOC/C(N2C=CN=C2)=N\C1=CC=C(C=C1C(F)(F)F)Cl,rat,70,fc; food concentration,104 weeks,100,3.5,400,14
+1165,112,Triflumuron,Krötlinger,1984,DAR,2005,"urea, benzoyl",insecticide,64628-44-0,2-chloro-N-[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]benzamide,FC(F)(F)OC(C=C2)=CC=C2NC(NC(C1=C(Cl)C=CC=C1)=O)=O,rat,50,fc; food concentration,104 weeks,20,0.8199999928,200,8.449999809
+1166,54,Trifluralin,Emmerson,1980,DAR,2003,dinitroaniline,herbicide,1582-09-8,"2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine",O=[N+]([O-])C1=CC(C(F)(F)F)=CC([N+]([O-])=O)=C1N(CCC)CCC,rat,30,fc; food concentration,104 weeks,0,0,813,30
+2682,54,Trifluralin,Worth,1966,DAR,2003,dinitroaniline,herbicide,1582-09-8,"2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine",O=[N+]([O-])C1=CC(C(F)(F)F)=CC([N+]([O-])=O)=C1N(CCC)CCC,rat,6,fc; food concentration,104 weeks,2000,84,20000,480
+2683,54,Trifluralin,Thomas,1978,DAR,2003,dinitroaniline,herbicide,1582-09-8,"2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine",O=[N+]([O-])C1=CC(C(F)(F)F)=CC([N+]([O-])=O)=C1N(CCC)CCC,rat,50,fc; food concentration,104 weeks,0,0,0,0
+6108,2786,Triflusulfuron,Biegel,1993,DAR,2007,,,,,CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)O,rat,62,fc; food concentration,104 weeks,100,4.059999943,750,30.60000038
+1167,116,Triflusulfuron-methyl,Biegel,1993,DAR,2007,"urea, triazinylsulfonyl",herbicide,126535-15-7,"2-(((((4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)-3-methylbenzoic acid",O=S(C1=C(C)C=CC=C1C(OC)=O)(NC(NC2=NC(OCC(F)(F)F)=NC(N(C)C)=N2)=O)=O,rat,62,fc; food concentration,104 weeks,100,4.059999943,750,30.60000038
+1168,55,Triforin,Everett,1992,JMPR,1997,others,fungicide,26644-46-2,"N,N'-[1,4-piperazinediylbis(2,2,2-trichloroethyidene)]bisformamide",ClC(Cl)(Cl)C(N1CCN(C(NC=O)C(Cl)(Cl)Cl)CC1)NC=O,rat,70,fc; food concentration,104 weeks,200,10,2000,100
+5274,55,Triforin,Hill,1974,JMPR,1997,others,fungicide,26644-46-2,"N,N'-[1,4-piperazinediylbis(2,2,2-trichloroethyidene)]bisformamide",ClC(Cl)(Cl)C(N1CCN(C(NC=O)C(Cl)(Cl)Cl)CC1)NC=O,rat,35,fc; food concentration,104 weeks,625,31,3120,160
+1169,71,Trinexapac-ethyl,Giknis,1992,DAR,2005,benzoic acid,plant growth regulator,95266-40-3,"ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate",O=C/1CC(C(O)=O)CC(C1=C(C2CC2)\O)=O,rat,90,fc; food concentration,104 weeks,3000,116,10000,393
+1170,147,Triticonazol,Aughton,1994,DAR,2005,triazole,fungicide,131983-72-7,"5-[(4-chlorophenyl)methylene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol",OC1(CN3N=CN=C3)C(C)(C)CC/C1=C\C2=CC=C(Cl)C=C2,rat,,fc; food concentration,104 weeks,750,29.39999962,5000,203.6000061
+6139,944,Tritosulfuron,Mellert,2001,DAR,2002,"urea, triazinylsulfonyl",herbicide,142469-14-5,"N-[[[4-methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-yl]amino]carbonyl]-2-(trifluoromethyl)benzenesulfonamide",FC(F)(F)C1=CC=CC=C1S(NC(NC2=NC(C(F)(F)F)=NC(OC)=N2)=O)(=O)=O,rat,50,fc; food concentration,104 weeks,1000,48,3500,0
+6518,944,Tritosulfuron,Mellert,2001,DAR,2002,"urea, triazinylsulfonyl",herbicide,142469-14-5,"N-[[[4-methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-yl]amino]carbonyl]-2-(trifluoromethyl)benzenesulfonamide",FC(F)(F)C1=CC=CC=C1S(NC(NC2=NC(C(F)(F)F)=NC(OC)=N2)=O)(=O)=O,rat,20,fc; food concentration,52 weeks,1000,51.70000076,3500,0
+6687,2051,Valifenalat,Webley,2004,EFSA,2012,acylamino acid,fungicide,283159-90-0,"N-[(1-methylethoxy)carbonyl]-L-valyl-3-(4-chlorophenyl)-β-alanine, methyl ester",CC(C)OC(NC(C(C)C)C(NC(C1=CC=C(Cl)C=C1)CC(OC)=O)=O)=O,rat,50,fd; food dose,104 weeks,0,150,0,1000
+1171,57,Vinclozolin,Mellert,1993,JMPR,1995,dicarboximide,fungicide,50471-44-8,"(+-)-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione",O=C(OC(C)1C=C)N(C2=CC(Cl)=CC(Cl)=C2)C1=O,rat,20,fc; food concentration,104 weeks,50,2.799999952,150,8
+5410,57,Vinclozolin,Mellert,1994,JMPR,1995,dicarboximide,fungicide,50471-44-8,"(+-)-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione",O=C(OC(C)1C=C)N(C2=CC(Cl)=CC(Cl)=C2)C1=O,rat,50,fc; food concentration,104 weeks,0,0,50,2.700000048
+5480,58,Zineb,Blackwell-Smith,1953,JMPR,1993,"dithiocarbamate, alkylenebis",fungicide,12122-67-7,"[[1,2-ethanediylbis[carbamodithioato]](2-)]zinc",[S]C(NCCNC(S[Zn])=S)=S,rat,10,fc; food concentration,104 weeks,0,0,500,0
+5310,59,Ziram,NTP,1983,JMPR,1996,"dithiocarbamate, dimethyl",fungicide,137-30-4,"(T-4)-bis(dimethyldithiocarbamato-S,S')zinc",CN(C)C(S[Zn]SC(N(C)C)=S)=S,rat,50,fc; food concentration,104 weeks,0,0,300,13
+5311,59,Ziram,Powell,1994,JMPR,1996,"dithiocarbamate, dimethyl",fungicide,137-30-4,"(T-4)-bis(dimethyldithiocarbamato-S,S')zinc",CN(C)C(S[Zn]SC(N(C)C)=S)=S,rat,70,fc; food concentration,104 weeks,0,0,60,2.5
+1172,312,Zoxamid,Ivett,1998,JMPR,2007,carboxamide,fungicide,156052-68-5,"N-(1-chloro-3-methyl-e-oxopent-3-yl)-3,5-dichloro-4-methylbezamide",CC(C(Cl)=C1)=C(Cl)C=C1C(NC(C)(CC)C(CCl)=O)=O,rat,70,fc; food concentration,104 weeks,20000,1058,0,0
\ No newline at end of file diff --git a/data/NOAEL-LOAEL_dv.xlsx b/data/NOAEL-LOAEL_dv.xlsx Binary files differnew file mode 100644 index 0000000..2c50100 --- /dev/null +++ b/data/NOAEL-LOAEL_dv.xlsx diff --git a/data/common.csv b/data/common.csv new file mode 100644 index 0000000..db3c68f --- /dev/null +++ b/data/common.csv @@ -0,0 +1,59 @@ +BrC1COC(C1)(Cn1cncn1)c1ccc(cc1Cl)Cl,0.017185,"mazzatorta, swiss" +c1ccc(cc1)Nc1ccccc1,0.14773,"mazzatorta, swiss" +c1scc(n1)c1nc2c([nH]1)cccc2,0.19876,"mazzatorta, swiss" +Cc1nc(Nc2ccccc2)nc(c1)C1CC1,0.15802,"mazzatorta, swiss" +CC(=CC1C(C1(C)C)C(=O)OCc1cccc(c1)Oc1ccccc1)C,0.42802,"mazzatorta, swiss" +CC(Cc1ccc(cc1)C(C)(C)C)CN1CC(C)OC(C1)C,0.0056016,"mazzatorta, swiss" +CCCC1COC(O1)(Cn1cncn1)c1ccc(cc1Cl)Cl,0.28052,"mazzatorta, swiss" +CCCCN(SN(C(=O)Oc1cccc2c1OC(C2)(C)C)C)CCCC,0.065695,"mazzatorta, swiss" +CCCCOCCOCCOCc1cc2OCOc2cc1CCC,0.29547,"mazzatorta, swiss" +C=CCOC(c1ccc(cc1Cl)Cl)Cn1cncc1,0.050475,"mazzatorta, swiss" +CCN(C(=O)C(Oc1cccc2c1cccc2)C)CC,0.36852,"mazzatorta, swiss" +CCOc1ccc2c(c1)C(=CC(N2)(C)C)C,0.055221,"mazzatorta, swiss" +CC(Oc1cccc(c1)NC(=O)c1ccccc1C(F)(F)F)C,0.26909,"mazzatorta, swiss" +CCOC(=O)c1cn2nc(cc2nc1C)OP(=S)(OCC)OCC,0.010713,"mazzatorta, swiss" +CCOC(=O)C(Cc1cc(c(cc1Cl)F)n1nc(n(c1=O)C(F)F)C)Cl,0.029113,"mazzatorta, swiss" +CCOP(=O)(Oc1ccc(c(c1)C)SC)NC(C)C,0.005604,"mazzatorta, swiss" +CCOP(=S)(Oc1nc(Cl)c(cc1Cl)Cl)OCC,0.0028524,"mazzatorta, swiss" +CCOP(=S)(Oc1nc(Cl)c(cc1Cl)Cl)OCC,0.028524,"mazzatorta, swiss" +CCOP(=S)(Oc1ncn(n1)c1ccccc1)OCC,0.0041492,"mazzatorta, swiss" +CCSCSP(=S)(OCC)OCC,0.00061449,"mazzatorta, swiss" +Clc1ccccc1c1nnc(nn1)c1ccccc1Cl,0.057068,"mazzatorta, swiss" +Clc1cc(Cl)c(cc1n1nc(n(c1=O)C(F)F)C)NS(=O)(=O)C,0.17304,"mazzatorta, swiss" +ClC1C(Cl)C(Cl)C(C(C1Cl)Cl)Cl,0.016161,"mazzatorta, swiss" +ClC(=CC1C(C1(C)C)C(=O)OCc1cccc(c1)Oc1ccccc1)Cl,0.063892,"mazzatorta, swiss" +ClC(SN1C(=O)C2C(C1=O)CC=CC2)(Cl)Cl,0.33268,"mazzatorta, swiss" +CNC(=O)Oc1cccc2c1OC(C2)(C)C,0.022599,"mazzatorta, swiss" +CN(C(=O)Oc1nc(nc(c1C)C)N(C)C)C,0.051619,"mazzatorta, swiss" +CN(C(=S)SSC(=S)N(C)C)C,0.04991,"mazzatorta, swiss" +COc1cccc(c1C)C(=O)NN(C(C)(C)C)C(=O)c1cc(C)cc(c1)C,1.1154,"mazzatorta, swiss" +COCC(N(c1c(C)cccc1CC)C(=O)CCl)C,0.52855,"mazzatorta, swiss" +COCN(c1c(CC)cccc1CC)C(=O)CCl,0.051897,"mazzatorta, swiss" +COC(=O)c1c(Cl)c(Cl)c(c(c1Cl)Cl)C(=O)OC,0.030124,"mazzatorta, swiss" +COC(=O)c1c(nc(c(c1CC(C)C)C1=NCCS1)C(F)(F)F)C(F)F,0.11151,"mazzatorta, swiss" +COC(=O)N(c1ccccc1COc1ccn(n1)c1ccc(cc1)Cl)OC,0.023207,"mazzatorta, swiss" +COC(=O)N(C(=O)N1COC2(C(=N1)c1ccc(cc1C2)Cl)C(=O)OC)c1ccc(cc1)OC(F)(F)F,0.0068203,"mazzatorta, swiss" +COC(=O)NC(=S)Nc1ccccc1NC(=S)NC(=O)OC,0.09346,"mazzatorta, swiss" +COC(=O)NS(=O)(=O)c1ccc(cc1)N,0.78179,"mazzatorta, swiss" +CON(C(=O)Nc1ccc(c(c1)Cl)Cl)C,0.025091,"mazzatorta, swiss" +COP(=O)(NC(=O)C)SC,0.013649,"mazzatorta, swiss" +COP(=O)(OC=C(Cl)Cl)OC,0.010408,"mazzatorta, swiss" +COP(=O)(SC)N,0.0020549,"mazzatorta, swiss" +CSc1ccc(cc1C)OP(=S)(OC)OC,0.0025869,"mazzatorta, swiss" +N#Cc1sc2=c(sc1C#N)c(=O)c1c(c2=O)cccc1,0.020248,"mazzatorta, swiss" +N#CC(c1cccc(c1)Oc1ccccc1)OC(=O)C1C(C1(C)C)C=C(Br)Br,0.0049485,"mazzatorta, swiss" +N#CC(c1cccc(c1)Oc1ccccc1)OC(=O)C1C(C1(C)C)C=C(Cl)Cl,0.12011,"mazzatorta, swiss" +N#CC(c1cccc(c1)Oc1ccccc1)OC(=O)C1C(C1(C)C)C=C(Cl)Cl,0.18016,"mazzatorta, swiss" +N#CC(c1cccc(c1)Oc1ccccc1)OC(=O)C(c1ccc(cc1)Cl)C(C)C,0.059538,"mazzatorta, swiss" +Oc1ccccc1c1ccccc1,5.8752,"mazzatorta, swiss" +O=C(c1ccc(cc1S(=O)(=O)C)C(F)(F)F)c1cnoc1C1CC1,0.055661,"mazzatorta, swiss" +O=C(C1(C)CCCCC1)Nc1ccc(c(c1Cl)Cl)O,0.96626,"mazzatorta, swiss" +O=Cc1ccco1,0.62445,"mazzatorta, swiss" +OC(C(C)(C)C)C(n1cncn1)Oc1ccc(cc1)c1ccccc1,0.074093,"mazzatorta, swiss" +O=C(C(C)(C)C)C(n1ncnc1)Oc1ccc(cc1)Cl,0.38809,"mazzatorta, swiss" +O=CNC(C(Cl)(Cl)Cl)N1CCN(CC1)C(C(Cl)(Cl)Cl)NC=O,0.22991,"mazzatorta, swiss" +OC(=O)CNCP(=O)(O)O,1.7744,"mazzatorta, swiss" +OC(=O)COc1ccc(cc1Cl)Cl,0.022621,"mazzatorta, swiss" +OC(=O)C(Oc1ccc(cc1)Oc1ncc(cc1Cl)C(F)(F)F)C,0.00027647,"mazzatorta, swiss" +OC(=O)COc1nc(F)c(c(c1Cl)N)Cl,1.9605,"mazzatorta, swiss" +O=S1OCC2C(CO1)C1(C(C2(Cl)C(=C1Cl)Cl)(Cl)Cl)Cl,0.0071266,"mazzatorta, swiss" diff --git a/data/functional-groups-smarts.csv b/data/functional-groups-smarts.csv new file mode 100644 index 0000000..d9bcd5f --- /dev/null +++ b/data/functional-groups-smarts.csv @@ -0,0 +1,35 @@ +Alkene,'[CX3;$([H2]),$([H1][#6]),$(C([#6])[#6])]=[CX3;$([H2]),$([H1][#6]),$(C([#6])[#6])] ' +Alkylchloride,'[ClX1][CX4]' +Alkylfluoride,'[FX1][CX4]' +Alcohol,'[OX2H][CX4;!$(C([OX2H])[O,S,#7,#15])]' +Dialkylether,'[OX2]([CX4;!$(C([OX2])[O,S,#7,#15,F,Cl,Br,I])])[CX4;!$(C([OX2])[O,S,#7,#15])]' +Alkylarylether,'[OX2](c)[CX4;!$(C([OX2])[O,S,#7,#15,F,Cl,Br,I])]' +Diarylether,'[c][OX2][c]' +Amine,'[NX3+0,NX4+;!$([N]~[!#6]);!$([N]*~[#7,#8,#15,#16])]' +Primary_arom_amine,'[NX3H2+0,NX4H3+]c' +Ketone,'[#6][CX3](=[OX1])[#6]' +Chloroalkene,'[ClX1][CX3]=[CX3]' +Carboxylic_acid,'[CX3;$([R0][#6]),$([H1R0])](=[OX1])[$([OX2H]),$([OX1-])]' +Carboxylic_acid_derivative,'[$([#6X3H0][#6]),$([#6X3H])](=[!#6])[!#6]' +Amide,'[CX3;$([R0][#6]),$([H1R0])](=[OX1])[#7X3;$([H2]),$([H1][#6;!$(C=[O,N,S])]),$([#7]([#6;!$(C=[O,N,S])])[#6;!$(C=[O,N,S])])]' +Secondary_amide,'[CX3;$([R0][#6]),$([H1R0])](=[OX1])[#7X3H1][#6;!$(C=[O,N,S])]' +Imidolactone,'[#6R][#6X3R](=,:[#7X2;$([H1]),$([H0][#6;!$(C=[O,N,S])])])[OX2][#6;!$(C=[O,N,S])]' +Nitrile,'[NX1]#[CX2]' +Vinylogous_ester,'[#6X3](=[OX1])[#6X3]=,:[#6X3][#6;!$(C=[O,N,S])]' +Vinylogous_halide,'[#6X3](=[OX1])[#6X3]=,:[#6X3][FX1,ClX1,BrX1,IX1]' +Carbonic_acid_derivatives,'[!#6][#6X3](=[!#6])[!#6]' +Urethan,'[#7X3][#6](=[OX1])[#8X2][#6]' +Phenol,'[OX2H][c]' +Arylchloride,'[Cl][c]' +Arylfluoride,'[F][c]' +Oxoarene,'[c]=[OX1]' +Heteroaromatic,'[a;!c]' +Nitro,'[$([NX3](=O)=O),$([NX3+](=O)[O-])][!#8]' +Sulfonic_derivative,'[SX4;$([H1]),$([H0][#6])](=[!#6])(=[!#6])[!#6]' +Sulfenic_derivative,'[SX2;$([H1]),$([H0][#6])][!#6]' +Phosphoric_acid_derivative,'[PX4D4](=[!#6])([!#6])([!#6])[!#6]' +Aromatic,'a' +Heterocyclic,'[!#6;!R0]' +Trifluoromethyl,'[FX1][CX4;!$([H0][Cl,Br,I]);!$([F][C]([F])([F])[F])]([FX1])([FX1])' +Michael_acceptor,'[CX3]=[CX3][$([CX3]=[O,N,S]),$(C#[N]),$([S,P]=[OX1]),$([NX3]=O),$([NX3+](=O)[O-])]' +CH-acidic,'[$([CX4;!$([H0]);!$(C[!#6;!$([P,S]=O);!$(N(~O)~O)])][$([CX3]=[O,N,S]),$(C#[N]),$([S,P]=[OX1]),$([NX3]=O),$([NX3+](=O)[O-]);!$(*[S,O,N;H1,H2]);!$([*+0][S,O;X1-])]),$([CX4;!$([H0])]1[CX3]=[CX3][CX3]=[CX3]1)]' diff --git a/functional-groups.txt b/data/functional-groups.txt index e14fd6c..e14fd6c 100644 --- a/functional-groups.txt +++ b/data/functional-groups.txt diff --git a/functional-groups.yaml b/data/functional-groups.yaml index eb6e5f4..eb6e5f4 100644 --- a/functional-groups.yaml +++ b/data/functional-groups.yaml diff --git a/data/mazzatorta.csv~ b/data/mazzatorta.csv~ new file mode 100644 index 0000000..6c4908d --- /dev/null +++ b/data/mazzatorta.csv~ @@ -0,0 +1,568 @@ +SMILES,LOAEL,Dataset +ClC12C3C4(C(C1(Cl)Cl)(C1(C2(C3(Cl)C(C41Cl)(Cl)Cl)Cl)Cl)Cl)Cl,1.9566e-05,mazzatorta +ClC1=C(Cl)C2(C(C1(Cl)C1C2C2CC1C=C2)(Cl)Cl)Cl,2.7404e-05,mazzatorta +ClC1C2OC2C2C1C1(Cl)C(=C(C2(C1(Cl)Cl)Cl)Cl)Cl,6.4215e-05,mazzatorta +ClC1=C(Cl)C2(C(C1(Cl)C1C2C2CC1C1C2O1)(Cl)Cl)Cl,0.00013126,mazzatorta +N#Cc1nn(c(c1S(=O)C(F)(F)F)N)c1c(Cl)cc(cc1Cl)C(F)(F)F,0.00013725,mazzatorta +CCSCCSP(=S)(OCC)OCC,0.00014577,mazzatorta +CCOP(=S)(SCSC(C)(C)C)OCC,0.00017335,mazzatorta +CCOP(=S)(SCSC(C)(C)C)OCC,0.00020802,mazzatorta +ClC1=C(Cl)C2(C(C1(Cl)C1C2C2CC1C1C2O1)(Cl)Cl)Cl,0.00026253,mazzatorta +OC(=O)C(Oc1ccc(cc1)Oc1ncc(cc1Cl)C(F)(F)F)C,0.00027647,mazzatorta +ClC1=C(Cl)C2(C(C1(Cl)C1C2C2CC1C1C2O1)(Cl)Cl)Cl,0.00032816,mazzatorta +CCSCCSP(=S)(OCC)OCC,0.00036443,mazzatorta +ClC1C2OC2C2C1C1(Cl)C(=C(C2(C1(Cl)Cl)Cl)Cl)Cl,0.00051372,mazzatorta +CNC(=O)ON=CC(SC)(C)C,0.00052559,mazzatorta +ClC1CC2C(C1Cl)C1(C(C2(Cl)C(=C1Cl)Cl)(Cl)Cl)Cl,0.00061009,mazzatorta +CCSCSP(=S)(OCC)OCC,0.00061449,mazzatorta +OC1CCCCCc2cc(O)cc(c2C(=O)OC(CCC1)C)O,0.00062036,mazzatorta +ClC1=C(Cl)C2(C(C1(Cl)C1C2C2CC1C1C2O1)(Cl)Cl)Cl,0.00065632,mazzatorta +ClC1CC2C(C1Cl)C1(C(C2(Cl)C(=C1Cl)Cl)(Cl)Cl)Cl,0.00065889,mazzatorta +ClC1C=CC2C1C1(Cl)C(=C(C2(C1(Cl)Cl)Cl)Cl)Cl,0.00066967,mazzatorta +ClC(C(c1ccc(cc1)Cl)c1ccc(cc1)Cl)(Cl)Cl,0.00070525,mazzatorta +COP(=O)(SC)N,0.00070857,mazzatorta +CCSCCSP(=S)(OCC)OCC,0.00080174,mazzatorta +c1ccc(cc1)[Sn](c1ccccc1)c1ccccc1,0.00085711,mazzatorta +CCOP(=O)(SC(CC)C)SC(CC)C,0.00092458,mazzatorta +COP(=S)(Oc1ccc(cc1)N(=O)=O)OC,0.00094982,mazzatorta +ClC1C=CC2C1C1(Cl)C(=C(C2(C1(Cl)Cl)Cl)Cl)Cl,0.0010179,mazzatorta +Clc1c(Cl)c(Cl)c(c(c1Cl)Cl)Cl,0.0010183,mazzatorta +CNC(=O)CSP(=S)(OC)OC,0.0010905,mazzatorta +COC1CC(OC2C(C)C=CC=C3COC4C3(O)C(C=C(C4O)C)C(=O)OC3CC(CC=C2C)OC2(C3)C=CC(C(O2)C(C)C)C)OC(C1OC1CC(OC)C(C(O1)C)NC(=O)C)C,0.001111,mazzatorta +COP(=S)(SCn1nnc2c(c1=O)cccc2)OC,0.0011345,mazzatorta +ClC1CC2C(C1Cl)C1(C(C2(Cl)C(=C1Cl)Cl)(Cl)Cl)Cl,0.0012202,mazzatorta +ClC12C(Cl)(Cl)C3(C4(C1(Cl)C1(C2(Cl)C3(C4(C1(Cl)Cl)Cl)Cl)Cl)Cl)Cl,0.0012831,mazzatorta +CCOP(=S)(Oc1ccc(cc1)N(=O)=O)OCC,0.001442,mazzatorta +CCOP(=S)(Oc1ccccc1C(=O)OC(C)C)NC(C)C,0.0014476,mazzatorta +CCOc1cc(nc(n1)CC)OP(=S)(OC)OC,0.0015396,mazzatorta +COC(=O)C=C(OP(=O)(OC)OC)C,0.0015615,mazzatorta +CSc1ccc(cc1C)OP(=S)(OC)OC,0.0016168,mazzatorta +COP(=S)(Oc1ccc(c(c1)C)[N+](=O)[O-])OC,0.0016592,mazzatorta +ClC1C2(Cl)C3C4C5C1(Cl)C(C2(Cl)C5C3C1C4O1)(Cl)Cl,0.0018377,mazzatorta +CNC(=O)CCSCCSP(=O)(OC)OC,0.0018793,mazzatorta +CNC(=O)C=C(OP(=O)(OC)OC)C,0.0020165,mazzatorta +COP(=O)(SC)N,0.0020549,mazzatorta +CCOP(=S)(Oc1ccc2c(c1)oc(=O)c(c2C)Cl)OCC,0.0022053,mazzatorta +S=C1NCCN1,0.0022514,mazzatorta +CO[C@H]1C[C@H](O[C@H]2[C@@H](C)C=CC=C3CO[C@H]4[C@]3(O)[C@@H](C=C([C@H]4O)C)C(=O)O[C@H]3C[C@@H](CC=C2C)O[C@]2(C3)C=C[C@@H]([C@H](O2)[C@H](CC)C)C)O[C@H]([C@@H]1O[C@H]1C[C@H](OC)[C@H]([C@@H](O1)C)O)C,0.0022907,mazzatorta +S=C1NCCN1,0.0024472,mazzatorta +CSc1ccc(cc1C)OP(=S)(OC)OC,0.0025869,mazzatorta +COc1sc(=O)n(n1)CSP(=S)(OC)OC,0.0026461,mazzatorta +COC(=O)C(Oc1ccc(cc1)Oc1ncc(cc1Cl)C(F)(F)F)C,0.0026615,mazzatorta +COC1CC(OC2C(C)C=CC=C3COC4C3(O)C(C=C(C4O)C)C(=O)OC3CC(CC=C2C)OC2(C3)C=CC(C(O2)C(C)C)C)OC(C1OC1CC(OC)C(C(O1)C)NC(=O)C)C,0.0027775,mazzatorta +CCOP(=S)(Oc1nc(Cl)c(cc1Cl)Cl)OCC,0.0028524,mazzatorta +CCOP(=S)(OCC)SCSc1ccc(cc1)Cl,0.0029166,mazzatorta +c1ccn2c(c1)c1ccccn1CC2,0.0029334,mazzatorta +c1ccn2c(c1)c1ccccn1CC2,0.0029848,mazzatorta +CCCCSP(=O)(SCCCC)SCCCC,0.0039744,mazzatorta +COc1sc(=O)n(n1)CSP(=S)(OC)OC,0.0041345,mazzatorta +CCOP(=S)(Oc1ncn(n1)c1ccccc1)OCC,0.0041492,mazzatorta +CCOP(=O)(OC(=CCl)c1ccc(cc1Cl)Cl)OCC,0.0041717,mazzatorta +Clc1nc(nc(n1)Cl)Nc1ccccc1Cl,0.0041739,mazzatorta +Clc1cccc(n1)C(Cl)(Cl)Cl,0.0043308,mazzatorta +N#CC(c1cccc(c1)Oc1ccccc1)OC(=O)C1C(C1(C)C)C(C(Br)(Br)Br)Br,0.0045112,mazzatorta +CCOP(=S)(Oc1ccc2c(c1)oc(=O)c(c2C)Cl)OCC,0.0046862,mazzatorta +CCOP(=S)(Oc1cc(C)nc(n1)C(C)C)OCC,0.0049286,mazzatorta +CCOP(=O)(Oc1ccc(c(c1)C)SC)NC(C)C,0.0049447,mazzatorta +N#CC(c1cccc(c1)Oc1ccccc1)OC(=O)C1C(C1(C)C)C=C(Br)Br,0.0049485,mazzatorta +N#CC(c1cccc(c1)Oc1ccccc1)OC(=O)C(C(C)C)Nc1ccc(cc1Cl)C(F)(F)F,0.004971,mazzatorta +CCN(C(=O)C(=C(OP(=O)(OC)OC)C)Cl)CC,0.0050052,mazzatorta +CCNc1nc(nc(n1)Cl)NC(C#N)(C)C,0.0051933,mazzatorta +CCOP(=S)(OCC)SCSP(=S)(OCC)OCC,0.0052019,mazzatorta +COP(=O)(OC(C(Br)(Cl)Cl)Br)OC,0.0052523,mazzatorta +COc1sc(=O)n(n1)CSP(=S)(OC)OC,0.0052922,mazzatorta +CCOP(=S)(SCn1c(=O)oc2c1ccc(c2)Cl)OCC,0.0054376,mazzatorta +CC(Cc1ccc(cc1)C(C)(C)C)CN1CC(C)OC(C1)C,0.0056016,mazzatorta +CCOP(=O)(Oc1ccc(c(c1)C)SC)NC(C)C,0.005604,mazzatorta +Fc1ccc(cc1)[Si](c1ccc(cc1)F)(Cn1cncn1)C,0.0063413,mazzatorta +COC(=O)Nc1nc2c([nH]1)cc(cc2)S(=O)c1ccccc1,0.0063422,mazzatorta +ClCC(N1C(=O)c2c(C1=O)cccc2)SP(=S)(OCC)OCC,0.0063477,mazzatorta +COP(=O)(SC)N,0.0063771,mazzatorta +CCP(=S)(Sc1ccccc1)OCC,0.0064142,mazzatorta 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+Clc1ccccc1CC(C1(Cl)CC1)(Cn1nc[nH]c1=S)O,2.1786,swiss +COc1cc(OC)n2c(n1)nc(n2)NS(=O)(=O)c1c(OC)nccc1C(F)(F)F,2.3023,swiss +CO/N=C(\c1ccccc1COc1ccccc1C)/C(=O)OC,2.4002,swiss +COC(=O)CC(c1ccc(cc1)Cl)NC(=O)C(C(C)C)NC(=O)OC(C)C,2.507,swiss +COc1nn(c(=O)n1C)C(=O)NS(=O)(=O)c1ccccc1OC(F)(F)F,2.5233,swiss +COc1cc(OC)nc(n1)NC(=O)NS(=O)(=O)c1n2ccccc2nc1S(=O)(=O)CC,2.7557,swiss +CN(NC(=O)CCC(=O)O)C,3.0343,swiss +CCCOC(=O)NCCCN(C)C.Cl,3.0348,swiss +Oc1ccccc1c1ccccc1,3.1197,swiss +OC(=O)CNCP(=O)(O)O,3.3122,swiss +Cc1cnc2c(c1)ccc(c2C(=O)O)Cl,3.3388,swiss +[O-]P(=O)OCC.[O-]P(=O)OCC.[O-]P(=O)OCC.[Al+3],3.6854,swiss +Oc1ccc(nn1)O,4.4608,swiss +C[N+]1(C)CCCCC1.[Cl-],4.5703,swiss +Clc1cc(N)c(c(n1)C(=O)O)Cl,4.8306,swiss +CNC(=N[N](=O)[O])NCC1COCC1,4.9008,swiss +COc1cc(OC)nc(n1)NC(=O)NS(=O)(=O)c1ncccc1C(=O)N(C)C,5.0877,swiss +OC(=O)CNCP(=O)(O)O,5.5597,swiss +Oc1ccccc1c1ccccc1,5.8752,swiss +OC(=O)CNCP(=O)(O)O,7.1803,swiss diff --git a/data/test.csv b/data/test.csv~ index fc1cdce..fc1cdce 100644 --- a/data/test.csv +++ b/data/test.csv~ diff --git a/data/training.csv b/data/training.csv~ index b788ab5..b788ab5 100644 --- a/data/training.csv +++ b/data/training.csv~ diff --git a/figure/crossvalidation.pdf b/figures/crossvalidation.pdf Binary files differindex 5c31c0c..5c31c0c 100644 --- a/figure/crossvalidation.pdf +++ b/figures/crossvalidation.pdf diff --git a/figure/dataset-variability.pdf b/figures/dataset-variability.pdf Binary files differindex aad1c21..aad1c21 100644 --- a/figure/dataset-variability.pdf +++ b/figures/dataset-variability.pdf diff --git a/figure/functional-groups.pdf b/figures/functional-groups.pdf Binary files differindex ca189c8..ca189c8 100644 --- a/figure/functional-groups.pdf +++ b/figures/functional-groups.pdf diff --git a/figure/pc-small-compounds-highlighted.png b/figures/pc-small-compounds-highlighted.png Binary files differindex a893a65..a893a65 100644 --- a/figure/pc-small-compounds-highlighted.png +++ b/figures/pc-small-compounds-highlighted.png diff --git a/figure/test-correlation.pdf b/figures/test-correlation.pdf Binary files differindex d3f49a7..d3f49a7 100644 --- a/figure/test-correlation.pdf +++ b/figures/test-correlation.pdf diff --git a/figure/test-prediction.pdf b/figures/test-prediction.pdf Binary files differindex 2083f96..2083f96 100644 --- a/figure/test-prediction.pdf +++ b/figures/test-prediction.pdf @@ -163,7 +163,7 @@ of connected atoms. MolPrint2D fingerprints are generated dynamically from chemical structures and do not rely on predefined lists of fragments (such as OpenBabel FP3, FP4 or -MACCs fingerprints or lists of toxocophores/toxicophobes). This has the +MACCs fingerprints or lists of toxocophores/toxicophobes). That has the advantage the they may capture substructures of toxicological relevance that are not included in other fingerprints. Preliminary experiments have shown that predictions with MolPrint2D fingerprints are indeed more accurate than diff --git a/references.bibtex b/references.bibtex index 897490f..797ae9a 100644 --- a/references.bibtex +++ b/references.bibtex @@ -120,3 +120,13 @@ eprint = { journal = {J. of Stat. Soft}, year = {2008} } + +@article{Jeliazkova15, + author = {Nina Jeliazkova and Charalampos Chomenidis and Philip Doganis and Bengt Fadeel and Roland Grafström and Barry Hardy and Janna Hastings and Markus Hegi and Vedrin Jeliazkov and Nikolay Kochev and Pekka Kohonen and Cristian R. Munteanu and Haralambos Sarimveis and Bart Smeets and Pantelis Sopasakis and Georgia Tsiliki and David Vorgrimmler and Egon Willighagen }, + title = {The eNanoMapper database for nanomaterial safety information}, + journal = {Beilstein J. Nanotechnol.}, + pages = {1609–1634}, + number = {6}, + year = {2015}, + doi = {doi:10.3762/bjnano.6.165} +} diff --git a/scripts/correct-predictions.R b/scripts/correct-predictions.R new file mode 100755 index 0000000..f39d4fe --- /dev/null +++ b/scripts/correct-predictions.R @@ -0,0 +1 @@ +correct_predictions = 134 diff --git a/create-median-correlation.rb b/scripts/create-median-correlation.rb index 9a2f6f5..9a2f6f5 100644..100755 --- a/create-median-correlation.rb +++ b/scripts/create-median-correlation.rb diff --git a/create-test.rb b/scripts/create-test.rb index c186a11..782f172 100644..100755 --- a/create-test.rb +++ b/scripts/create-test.rb @@ -1,4 +1,6 @@ -require_relative "include.rb" +#!/usr/bin/env ruby +require_relative '../../lazar/lib/lazar' +include OpenTox old = Dataset.from_csv_file File.join(DATA,"mazzatorta.csv") new = Dataset.from_csv_file File.join(DATA,"swiss.csv") diff --git a/create-training.rb b/scripts/create-training.rb index acba25b..d05bc1c 100644..100755 --- a/create-training.rb +++ b/scripts/create-training.rb @@ -1,4 +1,6 @@ -require_relative 'include.rb' +#!/usr/bin/env ruby +require_relative '../../lazar/lib/lazar' +include OpenTox old = Dataset.from_csv_file File.join(DATA,"mazzatorta.csv") new = Dataset.from_csv_file File.join(DATA,"swiss.csv") diff --git a/crossvalidation-plots.R b/scripts/crossvalidation-plots.R index 2bc259f..2bc259f 100644..100755 --- a/crossvalidation-plots.R +++ b/scripts/crossvalidation-plots.R diff --git a/crossvalidation.rb b/scripts/crossvalidation.rb index 79aeb83..79aeb83 100644..100755 --- a/crossvalidation.rb +++ b/scripts/crossvalidation.rb diff --git a/dataset-variability.R b/scripts/dataset-variability.R index 775fd03..775fd03 100644..100755 --- a/dataset-variability.R +++ b/scripts/dataset-variability.R diff --git a/scripts/functional-groups-smarts.rb b/scripts/functional-groups-smarts.rb new file mode 100755 index 0000000..0fd0520 --- /dev/null +++ b/scripts/functional-groups-smarts.rb @@ -0,0 +1,14 @@ +#!/usr/bin/env ruby +require 'csv' + +smarts = {} +File.open("../functional-groups.txt").each_line do |row| + name,sma = row.chomp.split ": " + smarts[name] = "'#{sma}'" +end + +names = [] +CSV.foreach("../data/functional-groups-reduced4R.csv") do |row| + names << row[0].gsub(" ", "_") +end +names.uniq.each{|name| puts [name,smarts[name]].join ","} diff --git a/functional-groups.R b/scripts/functional-groups.R index 01f2043..01f2043 100644..100755 --- a/functional-groups.R +++ b/scripts/functional-groups.R diff --git a/functional-groups.rb b/scripts/functional-groups.rb index 9da2a18..9da2a18 100644..100755 --- a/functional-groups.rb +++ b/scripts/functional-groups.rb diff --git a/functional-groups4R.rb b/scripts/functional-groups4R.rb index 0b14b7a..0b14b7a 100644..100755 --- a/functional-groups4R.rb +++ b/scripts/functional-groups4R.rb diff --git a/include.rb b/scripts/include.rb index edc3a64..edc3a64 100644..100755 --- a/include.rb +++ b/scripts/include.rb diff --git a/scripts/mazzatorta-unique-smiles.rb b/scripts/mazzatorta-unique-smiles.rb new file mode 100755 index 0000000..0b6db2a --- /dev/null +++ b/scripts/mazzatorta-unique-smiles.rb @@ -0,0 +1,17 @@ +#!/usr/bin/env ruby +require_relative '../../lazar/lib/lazar' +include OpenTox + +csv_in = CSV.read(ARGV[0], :encoding => 'windows-1251:utf-8') +head = csv_in.shift +data = [] +data = [] +csv_in.each do |line| + c = Compound.from_smiles line[0] + # round to 5 significant digits in order to detect duplicates + mmol = line[1].to_f.signif(5) + data << [c.smiles,mmol,"mazzatorta"] #if c +end +data.sort!{|a,b| a[1] <=> b[1]} +puts ["SMILES","LOAEL","Dataset"].join "," +puts data.collect{|row| row.join ","}.join "\n" diff --git a/scripts/misclassification-predictions.rb b/scripts/misclassification-predictions.rb new file mode 100755 index 0000000..8d8c837 --- /dev/null +++ b/scripts/misclassification-predictions.rb @@ -0,0 +1,15 @@ +require_relative "include.rb" +dataset = Dataset.from_csv_file "data/training.csv" +compounds = CSV.read("data/misclassifications.csv")[1..2].collect{|m| Compound.from_smiles(m[0])} +model = Model::LazarRegression.create(dataset, :prediction_algorithm => "OpenTox::Algorithm::Regression.local_fingerprint_regression") +#predictions = compounds.collect{|c| model.predict c} +#predictions.each do |p| +#end +#p compounds[1].smiles +p compounds[1].names +prediction = model.predict compounds[1] +#prediction[:neighbors] = prediction[:neighbors].collect{|n| n.delete(:dataset_ids)} +prediction[:neighbors].each{|n| n.delete(:dataset_ids)} +#prediction[:neighbors] = prediction[:neighbors].collect{|n| n[:tanimoto]} +prediction[:neighbors] = prediction[:neighbors].collect{|n| Compound.find(n["_id"]).smiles} +puts JSON.pretty_generate(prediction) diff --git a/scripts/misclassifications.rb b/scripts/misclassifications.rb new file mode 100755 index 0000000..171077c --- /dev/null +++ b/scripts/misclassifications.rb @@ -0,0 +1,61 @@ +require_relative 'include.rb' + +class Range + def intersection(other) + return nil if (self.max < other.begin or other.max < self.begin) + [self.begin, other.begin].max..[self.max, other.max].min + end + alias_method :&, :intersection +end + +experimental = {} +CSV.foreach(File.join(DATA,"test.csv")) do |row| + experimental[row[0]] ||= [] + experimental[row[0]] << row[1].to_f +end + +predictions = {} +CSV.foreach(File.join(DATA,"training-test-predictions.csv"),:headers => true) do |row| + predictions[row[0]] = [-Math.log10(row[2].to_f),Math.log10(row[3].to_f).abs] +end + +outside_experimental_values = 0 +within_experimental_values = 0 +out = [] +predictions.each do |smi,pred| + exp = experimental[smi].collect{|e| -Math.log10(e)}.uniq + # https://en.wikipedia.org/wiki/Prediction_interval + min = pred[0]-1.96*pred[1] + max = pred[0]+1.96*pred[1] + pred = predictions[smi][0] + ci = predictions[smi][1] + err = nil + if (min..max) & (exp.min..exp.max) + within_experimental_values += 1 + else + outside_experimental_values += 1 + if exp.min < min + err = exp.min - min + elsif exp.max > max + err = exp.max - max + end + end + if err + out << { + :smi => smi, + :experimental => exp, + :min => min, + :max => max, + :prediction => predictions[smi][0], + :ci => predictions[smi][1], + :error => err + } + end +end + + +out.sort!{|a,b| b[:error].abs <=> a[:error].abs} +csv = [["SMILES","Distance"]] + out.collect{|o| [o[:smi], o[:error]]} +File.open("data/misclassifications.csv","w+"){|f| f.puts csv.collect{|r| r.join ", "}.join("\n")} + +#File.open("correct-predictions.R","w+"){|f| f.puts "correct_predictions = #{within_experimental_values}"} diff --git a/scripts/noael_loael2mmol.rb b/scripts/noael_loael2mmol.rb new file mode 100755 index 0000000..3d79aae --- /dev/null +++ b/scripts/noael_loael2mmol.rb @@ -0,0 +1,19 @@ +#!/usr/bin/env ruby +require_relative '../../lazar/lib/lazar' +include OpenTox +csv_in = CSV.read(ARGV[0], :encoding => 'windows-1251:utf-8') +head = csv_in.shift +data = [] +csv_in.each do |line| + smi = line[11] + mg = line[19] + unless mg.to_f == 0.0 + c = Compound.from_smiles smi + # round to 5 significant digits in order to detect duplicates + mmol = c.mg_to_mmol(mg.to_f).signif(5) + data << [c.smiles, mmol,"swiss"] + end +end +data.sort!{|a,b| a[1] <=> b[1]} +puts ["SMILES","LOAEL","Dataset"].join "," +puts data.collect{|row| row.join ","}.join "\n" diff --git a/test-correlation-plot.R b/scripts/test-correlation-plot.R index 74a2739..74a2739 100644..100755 --- a/test-correlation-plot.R +++ b/scripts/test-correlation-plot.R diff --git a/test-prediction-plot.R b/scripts/test-prediction-plot.R index db003d3..db003d3 100644..100755 --- a/test-prediction-plot.R +++ b/scripts/test-prediction-plot.R diff --git a/scripts/test-prediction.R b/scripts/test-prediction.R new file mode 100755 index 0000000..9b1ea76 --- /dev/null +++ b/scripts/test-prediction.R @@ -0,0 +1,15 @@ +training = read.csv("data/training-test-predictions.csv",header=T) +test <- read.csv("data/test.csv",header=T) +n = c("SMILES","LOAEL","Source") + +data = data.frame(factor(test$SMILES),test$LOAEL,factor(test$Dataset)) +names(data) = n +data$Type = "experimental" +comb = data.frame(factor(training$SMILES),training$LOAEL_predicted,factor(training$Dataset)) +names(comb) = n +comb$Type = "predicted" +print(data[comb$SMILES,]) +#data = rbind(data,comb) +#data$LOAEL = -log(data$LOAEL) +#data$SMILES <- reorder(data$SMILES,data$LOAEL) +#print(data) diff --git a/test-validation.rb b/scripts/test-validation.rb index 0bbcc42..0bbcc42 100644..100755 --- a/test-validation.rb +++ b/scripts/test-validation.rb diff --git a/unique-smiles.rb b/unique-smiles.rb deleted file mode 100644 index d35ce90..0000000 --- a/unique-smiles.rb +++ /dev/null @@ -1,19 +0,0 @@ -require_relative "include.rb" - -input = Dataset.from_csv_file File.join(ARGV[0]) -outname = File.join(File.dirname(ARGV[0]),"#{ARGV[1]}.csv") - -data = [] -input.compounds.each_with_index do |cid,i| - c = Compound.find cid - # round to 5 significant digits in order to detect duplicates - v = input.data_entries[i].first.signif(5) - data << [c.smiles,v,ARGV[1]] -end - -data.sort!{|a,b| a[1] <=> b[1]} - -CSV.open(outname,"w+") do |csv| - csv << ["SMILES","LOAEL","Dataset"] - data.each{|r| csv << r} -end |
